LOCUS       JX975347               11581 bp    DNA     linear   BCT 27-AUG-2013
DEFINITION  Salmonella enterica strain G2476 O antigen gene cluster, complete
            sequence.
ACCESSION   JX975347
VERSION     JX975347.1
KEYWORDS    .
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11581)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Reeves,P.R. and Wang,L.
  TITLE     Structural diversity in Salmonella O antigens and its genetic basis
  JOURNAL   FEMS Microbiol. Rev. (2013) In press
   PUBMED   23848592
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11581)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Reeves,P.R. and
            Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-OCT-2012) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..11581
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="G2476"
                     /db_xref="taxon:28901"
                     /note="serogroup: O57"
     misc_feature    1..11581
                     /note="O antigen gene cluster"
     gene            106..1191
                     /gene="rmlB"
     CDS             106..1191
                     /gene="rmlB"
                     /note="RmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase"
                     /protein_id="AFW04877.1"
                     /translation="MKILITGGAGFIGSAVVRHIIKNTQNTVVNIDKLTYAGNLESLS
                     DISESNRYNFEHADICDSAAITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEVARKYWSALGEDKKNSFRFHHISTDEVYGDLPHPDEAGNSVTLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KSLPIYGKGDQIRDWLYVEDHARALYIVVTEGKAGETYNIGGHNEKKNLDVVFTICDL
                     LDEIVPKATSYREQITYVADRPGHDRRYAIDADKISRELGWKPLETFESGIRKTVEWY
                     LANTKWVNNVKSGAYQSWIEQNYEGRQ"
     gene            1191..2090
                     /gene="rmlD"
     CDS             1191..2090
                     /gene="rmlD"
                     /note="RmlD"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-L-mannose-dehydrogenase"
                     /protein_id="AFW04878.1"
                     /translation="MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFCGDFSNPK
                     GVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANETGAWVVHY
                     STDYVFPGTGDIPWQETDITSPLNVYGKTKLAGEKALQDNGPKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALKKPEVAGLYHLVAG
                     GTTTWHDYAALIFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFG
                     LILPQWELGVKRMLTEMFTTTTI"
     gene            2132..3016
                     /gene="rmlA"
     CDS             2132..3016
                     /gene="rmlA"
                     /note="RmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="AFW04879.1"
                     /translation="MEMKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLS
                     TLMLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPNPDGLAQAFIIGEEFI
                     GNDDCALVLGDNIFYGHDLPKLMDVAINKENGATVFAYHVNDPERYGVVEFDQNGTAV
                     SLEEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSARGELEITDINRIYMEQGRLSVA
                     MMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDSQKVMSLAE
                     KLSKNAYGQYLINMIKGR"
     gene            3021..3569
                     /gene="rmlC"
     CDS             3021..3569
                     /gene="rmlC"
                     /note="RmlC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="AFW04880.1"
                     /translation="MKIIETEIPDVFILEPLVFVDERGFFMESFNHRVFETLLDTKVN
                     FVQDNHSKSTKNVVRGLHYQTEPYAQGKLVRCISGAVYDVAVDLRSTSQTYGCWVGVE
                     LSALNMRQLWIPEGFAHGFLTLTDNVEFLYKTTNYYNKESERCIRYNDPDLDIIWPIS
                     NKDNIIVSDKDKKGILFRDIKK"
     gene            3639..5198
                     /gene="wzx"
     CDS             3639..5198
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AFW04881.1"
                     /translation="MLATTVFRSVKYGIVFSIIIMILTFFVRKFFIESFGTELTGFYL
                     LMNQLIGYLNLAELGLTTASIYLFFKPINSGSENEIILFFYVIKKIYKVIAFSILILG
                     IFIAALLPILVTDDINWYNIYIPWVIFVISTALSYLYSAETVLLTASEKLYIVKIISG
                     ISRTACFLIQILILKNDGSFILFCTIEILYVGIQYYLFRNYVSKLHGKSIYKKVKDKS
                     LINDIKKNITNEIKKTFVHKMSGVLIFNTDYIIISLFIGLSTITIYSSYLMFIQAVAI
                     ILSTIVAPLGASIGNYLHRTNIHVAYRKFNIINIGFFALATVACVIYNNSSTNLVQMW
                     MGNSVMFPSDVVILLAINLFCLIARSAVDVFKVAFGYMSDIHLPLIEGFANLLFSLIL
                     VNFYGVKGVIYGTIFSNIAIIMMARPLYLYIYAFKLGAKKFVKDHYRLWIITILFLLI
                     IYKGYDKCLYILINKIAFTQWDINNTLVHFLINQFIFLIVTSIVTSFVYLLFFPKLFL
                     VIISFLRKKYE"
     gene            5191..6057
                     /gene="wdcA"
     CDS             5191..6057
                     /gene="wdcA"
                     /note="WdcA"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04882.1"
                     /translation="MNKIPIIIMTRNDGLFLNECVDSIIKNTEYPYNIYIIDNNSSDS
                     QHLQILEELSLLPNVSIFRNKNNLWVLGVNKYLEMINNKCKSPYFVLTDGDIKFPNIE
                     SAGCWLTRLVSYMIRYQCVGKIGISLNWELIESDPFYEEIYNQEKRLYHENKKIGELF
                     ISPVDTTAAIYRWDWSISGYKFYPDHIRYLRPELYSCRTPKNFNAFHLGWLNYKKKDS
                     TDIKKLDEKIKCFTIIGADLKKTQIAIASNEIKFFNKIFYRPMKVFWSLRRIIFILFY
                     TFRKGIRCYDNH"
     gene            6067..7104
                     /gene="wzy"
     CDS             6067..7104
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AFW04883.1"
                     /translation="MIPYIIVFLIFATIALLNYDRCKLFYSSMIFLGFACVMRGSDVD
                     RDYETYVNIYNYIIHGYSYTIEPTFFIISKISYLVAGTPFFIFILYGLLAIYFKAKFI
                     IDWSPYPLLSVIVYFSNVYLLHEMTQIRIGLASAIGFYSLKYLITNEKRKYFICIFVA
                     TLFHYSMVIFLFLPLFNVRKISSQYKLFYFILIVLLYFLYLFNIDLSLLIKYIDIGLI
                     QSKYNIYKEQVIDNGTNVNVFSVMQILNLLIIFFAMSYSSHFKENRKLILIVKVFSLG
                     PISLIFFSAIPGFALRLSELFTVGQIVLLPMLVKQIRQVKLAYLGVILLSFIILLNNL
                     YYLSLVKAYSI"
     gene            7104..7931
                     /gene="wdcB"
     CDS             7104..7931
                     /gene="wdcB"
                     /note="WdcB"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04884.1"
                     /translation="MNILPIIVLYKCQLENSECINTLLRLDNVSHLKEIFVYNNSPGI
                     ISIPDQYMGINVHKINDHENSGVSKAYNEGLKFAKKMNYEYVLLLDQDTSLPGDALVI
                     YKESLIANKYIKLFCPILKKNTGVICSPLLYRLHRGFPVNHFKAGKYEFDDFTPINSG
                     MLLNVDAALECGGYNEEVFLDFSDFQFIERFKKHNPCFYVVPLILYQDCSGDEVDPSK
                     LLIRFRLYCQCAKKCVREKIQDDFIYFLMVFARAVKMAVKTKRIDFIINFYKYYIRG"
     gene            7933..8682
                     /gene="wdcC"
     CDS             7933..8682
                     /gene="wdcC"
                     /note="WdcC"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04885.1"
                     /translation="MISVCIPTYNGEYYIEEQIDSILSEIGPDDEIIISDDGSTDSTL
                     SIIEEYKDPRIKVYKNSIKNINYFKDRTEILLKKVSLNVQNTLMHCQGDYIYLADQDD
                     IWIKGRIAKTISFLNTNSPTLVVCNCSVIDEDRNVTQDSYFDYISPSSNIFRTMVKSS
                     FHGCCMCFNRSLLDKLFPFPEYSIGHDLWIGLQAMKFKGVLFYSEPLLLYRRHSSTVT
                     MTGNKSSNTLNFKIKYRLMMLKEYLRIDKKR"
     gene            8679..9815
                     /gene="wdcD"
     CDS             8679..9815
                     /gene="wdcD"
                     /note="WdcD"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04886.1"
                     /translation="MKKIAHVIVLPKMAGSQKFCHALLSKINGYKKYILVSGCENVDI
                     DQRQEFINAFESINVEIIWCYYLKRNIGKSDIRGFIELYTIFKKYQFDIVHTNSTKPG
                     ILARIAARMSGVKKIVHTVHGISFYKGQNVIKRLIYWAIECVALQFGDINVCVNNYYL
                     KYYKKFFWKKNISVFNGYDFSELLLYANSNNVKCNNKKDNVFSFLFVGRLDIQKDPIT
                     LIKAFSILASKYPNIILDIVGDGELMEASKELACELGVKDLVRFHGWIKKPYSYFYNC
                     NAFVCPSLYEAFGFIFVEAAYFRKPIIATNVEGIPEVVLNNKMGFLVSPSNYLALAEK
                     MEILVNSRSLCKVMGDFGSRYVIENFDIQKCVKAYQSIYDNDLR"
     gene            9819..11426
                     /gene="wdcE"
     CDS             9819..11426
                     /gene="wdcE"
                     /codon_start=1
                     /transl_table=11
                     /product="WdcE"
                     /protein_id="AFW04887.1"
                     /translation="MIRVCIKIYFPYFISALLFFCFLFYFNKMDVFPFFLGESFCIYA
                     TLLYFEKRIIRGIIWSSFMVIVGFQMASLYTSGDLIIPLTLSNAGEYKALGFNLLIKL
                     FFIVFIFFLFSLPLYSRVFYCYNPYYKFMCLMAVCLPLINGPLLMFGKTLYAYYQQLT
                     FSPSYNYPEIAKKYLKIGIWNNSSSLLKVTKPNIIIIFAEGMSYSVIDSVNNKGLKLT
                     PNIDTLMDNSLVFRNYYNHTAATFRGLRGQLTSAYQYKDGIGAHNDGFFEISNEKVKA
                     TFDKRLVSLPEILSSSGYKTIFLSSTEKNSTLNAMLKTLSFDEVYGMGDFEFYQNDRM
                     TDKQTFLSLKKLVEKNKGNNFFIGVYTSGTHHGMDSPNLRYKDGMNSYYNKFYNFDHQ
                     LGEFINYLDSNGLMENTLLIITADHATFPTPAFNRAFDTDAKYFIDTIPLIIFGAGIK
                     HHIYDAKGANSLALAPTILNILNINNRPNYFLGCSLLDVKCNSRFYNISAIGNSFFMT
                     GPEKYPNYNVKELNVSEEILNFYNVSG"
BASE COUNT     3726 a   1701 c   2149 g   4005 t
ORIGIN
        1 attggtagct gtaagccaag ggcggtagcg tgtgtaacga cttgagtaat taatttttat
       61 tggcaaatta attaccacat taaatacgcc ttatggaata gaaaagtgaa gatacttatt
      121 actggcgggg caggctttat tggatctgct gttgttcgcc atatcattaa gaatacacag
      181 aatactgtag ttaatatcga caaattaacc tacgccggta atcttgaatc cctttctgat
      241 atttctgaaa gtaatcgcta taattttgaa cacgcggata tttgtgattc cgctgcaata
      301 acgcgtattt ttgagcagta ccagccggac gcggtgatgc atttggctgc ggaaagtcat
      361 gtggaccgtt cgattaccgg gccggcagct tttattgaaa ccaatatcgt cggtacttat
      421 gttcttcttg aagttgcgcg taaatattgg tctgcgcttg gtgaagataa aaaaaatagt
      481 ttccgttttc atcatatttc aactgatgaa gtttacggcg atttaccaca tcctgatgaa
      541 gctgggaata gcgttacgct gccgttattt actgaaacga cggcatatgc gccaagtagc
      601 ccctactctg cttcaaaagc atccagcgat catttagttc gagcctggag gcgtacttat
      661 ggtctgccaa caatcgttac caattgttct aataactatg gtccttatca tttccccgaa
      721 aaactgattc cgttggtcat tttgaatgca ctggaaggaa agtctttgcc aatttatggc
      781 aaaggggatc agattcgcga ctggctatat gtagaagatc acgctcgcgc gctttatatt
      841 gtagtgactg aaggtaaggc aggggagact tataacattg gtggacacaa tgagaagaaa
      901 aatctcgatg tggtatttac catctgtgat cttctggatg agattgtacc caaagcgact
      961 tcttatcgtg aacaaatcac ttatgtcgcg gatcgtccag gccatgatcg tcgttatgcc
     1021 attgatgcag ataaaattag tcgcgaatta ggctggaaac cgctggagac ctttgaaagc
     1081 ggtattcgta aaacagtgga atggtatctc gctaatacaa aatgggtaaa caatgttaaa
     1141 agtggggcgt atcagagctg gattgaacag aactatgaag gacgccagta atgaatatct
     1201 tactttttgg taagacaggg caagtaggct gggagttgca acgttctcta gcgccagtgg
     1261 ggaatctgat cgccctggat gtccattcaa aagagttttg cggtgatttt agcaatccaa
     1321 aaggcgttgc cgaaaccgtt cgtaagcttc gtcccgatgt gattgttaac gcagcagcac
     1381 atactgcagt agataaagca gagtctgaac cagaactagc gcagttactt aacgccacca
     1441 gtgtggaagc catcgctaaa gcggctaacg aaactggcgc atgggtagtg cattattcaa
     1501 ctgattatgt attccctggt accggcgata tcccatggca ggaaacggac atcacgtcgc
     1561 cgctaaatgt ctatggcaag accaaactag cgggagaaaa ggccctgcag gataacggcc
     1621 ctaaacacct tatcttccgc accagttggg tttatgcagg taagggcaat aatttcgcaa
     1681 agacaatgct tcgtctggcg aaagagcgtc agacactttc ggtcatcaac gatcagtacg
     1741 gtgcgccaac cggtgcggaa ttactggctg actgcacggc tcatgcgatc cgtgtggcgt
     1801 taaagaaacc agaagtagca ggtctttacc atctggtcgc cggtggaact acaacctggc
     1861 atgactacgc tgcgttaatc tttgacgagg cgcgcaaggc agggataacg cttgcgctta
     1921 ctgagcttaa tgctgtgccg accagcgcct atccgacgcc ggcgagcaga cctggaaatt
     1981 cgcgtcttaa tactgaaaag tttcagcgta attttggcct tattctgccg caatgggaat
     2041 taggggttaa gcgtatgctg actgaaatgt ttacgacgac aaccatctga taaatttaaa
     2101 tgcccataag ggcattttct gtgaatgaga aatggaaatg aaaacgcgta agggcattat
     2161 tttagcgggg ggctccggca ctcgccttta tcctgtgacc atggcggtaa gtaaacaatt
     2221 acttccaatc tatgataaac cgatgattta ctatccgctt tctacactta tgcttgcagg
     2281 cattcgggat atcctgatca tcagtacacc acaggatacg ccgcgttttc aacaactgct
     2341 gggagacggt agtcaatggg gactgaacct tcaatataaa gtacagccaa acccggatgg
     2401 tctggcgcag gcatttatta ttggcgaaga atttattggt aatgatgact gtgcattagt
     2461 gttgggggat aatatcttct atggtcacga tctacctaaa ctgatggacg ttgccattaa
     2521 taaagaaaat ggcgctacgg tatttgctta tcatgtaaac gatccggagc gctacggtgt
     2581 ggttgagttt gaccaaaatg gcacagccgt tagtctggaa gaaaaaccgt tacaaccgaa
     2641 gagtaattat gcagtaacgg ggctgtattt ttatgataac agcgtggtgg agatggcgaa
     2701 aaatcttaag ccttctgctc gcggtgagtt agaaatcacg gatattaacc gtatttatat
     2761 ggaacaagga cgcttgtcag ttgcgatgat ggggcgcggt tatgcctggc tggatacggg
     2821 gacgcatcag agtttgatag aggccagtaa ttttattgcg acgattgagg aacgtcaggg
     2881 attgaaagtc tcttgcccag aagagattgc ttatcgtaaa gggtttattg attcacaaaa
     2941 agttatgagc ttggctgaaa aattatccaa aaatgcatat ggacaatatt taataaatat
     3001 gattaaaggg agatagtatt atgaaaatta ttgaaaccga gatcccagat gtatttattt
     3061 tagagccttt agtattcgta gatgagcgcg gttttttcat ggagagtttt aatcatcggg
     3121 tatttgaaac attattagat actaaagtaa attttgtcca agataaccac tctaaatcaa
     3181 caaaaaatgt tgtcagagga ttacattatc aaactgagcc atatgcacaa ggtaaattag
     3241 tacgttgtat atcaggggcc gtttatgatg ttgcagtaga tttacgttct acttcccaaa
     3301 cttatgggtg ttgggtcgga gttgaattat cagcattaaa tatgaggcaa ctatggatcc
     3361 cagaaggttt tgcccatggt ttccttactt tgacagataa tgtggagttt ttatacaaaa
     3421 caactaacta ttataataaa gaaagcgagc ggtgcattag atataacgat ccagatcttg
     3481 atattatatg gcctatttca aataaggata atataatagt ttctgataaa gataaaaaag
     3541 gtatactgtt tagagatata aaaaaataag gtttttttat catagcgata cataaagata
     3601 ttgctatgat aaatcatttt ttgagccaag gtgcattaat gctcgctaca acagtttttc
     3661 ggtcagtcaa gtatgggata gtattttcca taataatcat gattcttacg ttttttgtaa
     3721 gaaagttttt tatcgaatca tttggtactg aacttactgg tttttattta ttgatgaacc
     3781 aattaatagg ctatcttaat ttggcggaac ttggattaac aaccgcttct atttatttgt
     3841 tttttaagcc tattaactca ggtagtgaaa atgaaattat actttttttc tatgtaataa
     3901 aaaaaatata taaggtaatt gcttttagca ttttaatcct aggtatattt attgctgcat
     3961 tattaccaat cttggtaaca gatgatatca attggtataa tatatatata ccatgggtta
     4021 tttttgttat ttcaacagcg ctttcatatt tgtatagcgc tgaaactgtt ttattaactg
     4081 caagtgaaaa actttatatt gtaaaaataa tttccggtat ttcacgaaca gcatgttttt
     4141 taattcaaat attaatttta aaaaatgatg gatcctttat attattttgt actattgaaa
     4201 ttttatatgt aggtattcaa tattacttat ttagaaatta tgtttcaaaa ttacatggga
     4261 agtctattta taaaaaggta aaagataaaa gtttaattaa tgacattaaa aagaacatta
     4321 caaatgaaat aaagaaaaca ttcgttcata aaatgtcagg agtactaata tttaatacgg
     4381 attatataat cataagtcta tttattggat tatcaacgat tactatttac tcatcgtatc
     4441 taatgtttat acaagcagta gccattattc tatctacaat agtagctccg ttaggtgcat
     4501 ccataggtaa ttatttacat agaacaaata tacatgtggc atatcgtaaa ttcaacataa
     4561 ttaatattgg tttttttgca ttagcaaccg ttgcttgtgt aatatataat aattcatcga
     4621 caaatttggt tcagatgtgg atggggaata gtgttatgtt tccgtctgat gtagtaatac
     4681 tccttgcaat taatcttttt tgtttaattg ccagaagcgc tgttgatgtc tttaaggtag
     4741 cattcggtta tatgtcagat atacacttgc cccttattga agggttcgcg aatctactct
     4801 tttctttaat attagtaaat ttctatggag tcaagggagt tatttatggc acaatatttt
     4861 cgaatattgc catcataatg atggctcgcc cattatatct atatatttat gcattcaaac
     4921 ttggggcaaa gaagttcgtt aaagaccact accgattatg gattataacg atactttttt
     4981 tgctgataat ctataaagga tatgataagt gtttatatat actaattaat aaaattgcat
     5041 ttactcaatg ggatataaat aatacgctcg ttcatttttt aattaatcaa tttatatttt
     5101 tgatagttac atcgatagtc acttcattcg tttatttgct ttttttccct aaactgttcc
     5161 tcgttattat atccttctta aggaagaaat atgaataaga ttcccattat tataatgaca
     5221 agaaatgacg gattgttttt aaatgaatgc gtagattcaa ttataaagaa tactgaatac
     5281 ccatataata tatacattat tgataataat tcttctgata gccagcatct acaaatcttg
     5341 gaagaattat ctttactacc aaatgtttct atatttagaa acaaaaacaa tttatgggta
     5401 ttaggagtta ataaatattt agaaatgata aataataaat gtaaatctcc atattttgta
     5461 ttaaccgatg gagatataaa atttccgaat attgaatcgg caggatgttg gttaactaga
     5521 ttggtttctt atatgataag atatcaatgt gttggtaaga ttggtatttc attaaactgg
     5581 gaactaattg aaagtgatcc attttatgag gaaatttata accaagaaaa aaggctgtac
     5641 catgaaaata aaaagatagg tgagcttttt atttcgccag tagatactac cgctgcgatc
     5701 tatcgttggg attggtctat tagtggctat aaattttatc ctgaccacat aagatatctt
     5761 cgtccagaat tatattcatg tagaactcct aaaaatttta atgcttttca tctgggttgg
     5821 ttgaactata aaaagaaaga cagcactgat atcaaaaagc tagatgaaaa aattaaatgt
     5881 tttactataa ttggcgctga cttaaaaaaa acacaaattg ccattgcaag taacgaaata
     5941 aaattcttta ataagatatt ttatagacct atgaaggttt tctggagcct tagacggatt
     6001 atatttattt tattctatac ttttagaaaa ggcatcaggt gttatgataa tcattgagag
     6061 tttataatga taccatatat aattgtattt cttatttttg caactattgc tttacttaat
     6121 tatgataggt gtaaactatt ttactcctcc atgatttttt tgggttttgc ctgtgtaatg
     6181 agaggaagtg acgtagatag ggattacgag acatatgtaa atatttataa ttatataatt
     6241 catggttata gttatacaat tgaaccaact ttttttataa tctcaaaaat ttcttattta
     6301 gtggctggga cccctttttt tatttttatt ctctatggct tgctggcgat ttactttaag
     6361 gctaagttta taatcgattg gtctccctat cctctacttt ctgttatagt ttacttttca
     6421 aatgtttatc tcttacatga gatgactcaa ataagaatag gtttagccag tgcgattgga
     6481 ttctatagcc taaaatatct tattactaat gaaaaaagaa aatattttat atgtatcttt
     6541 gttgcaaccc tttttcatta ttcaatggtt atttttttgt ttcttccatt attcaatgta
     6601 agaaaaatat cgtcacagta taaattattt tattttattc ttattgtatt attatatttt
     6661 ttgtatctgt ttaatataga tttatcactt ttaataaaat atattgatat aggattaata
     6721 caatcgaaat acaatatata taaggaacag gttatagata atggtactaa tgtaaatgtc
     6781 ttttcagtaa tgcaaatatt aaatttactt attatttttt ttgctatgtc atattcttcg
     6841 cattttaaag aaaatagaaa attaatttta atagtaaagg ttttttcatt aggccctatc
     6901 tcattaatat ttttctctgc aattcctgga tttgcgttaa gattaagtga attatttact
     6961 gtaggacaaa tagtattact tcctatgctt gtgaagcaga tacgacaagt aaaactggct
     7021 tatttaggtg ttatactttt atcgtttatc atactattga ataatttata ttatctgtca
     7081 cttgttaagg catattctat ttaatgaata tattaccaat tatagtttta tataaatgtc
     7141 agcttgaaaa ttcagaatgt ataaatacat tattgagact tgataatgtt tctcatctta
     7201 aggagatttt tgtatataac aattcccctg gtattatatc tattcctgat caatatatgg
     7261 gcataaatgt tcataagatt aatgatcacg aaaattctgg agtaagtaaa gcatataatg
     7321 aagggttgaa gtttgctaaa aagatgaact atgaatatgt tcttttactt gaccaggata
     7381 cgtcgctccc aggtgatgca ttagttattt ataaagagag tttgatagct aataaatata
     7441 ttaaactgtt ttgccctata ctaaaaaaga atactggtgt aatttgttcg ccattactct
     7501 atagattaca tagaggtttt ccggttaatc acttcaaagc aggaaaatac gaatttgatg
     7561 atttcactcc gattaatagt ggcatgcttt taaatgttga tgccgctctt gaatgtggtg
     7621 gttataatga agaagtattc ttggatttta gtgactttca atttattgaa cggttcaaaa
     7681 aacataatcc ttgcttttat gttgttccat taattttata tcaagattgt tctggggatg
     7741 aagttgatcc ctcgaagctg ttgattagat ttagactata ttgtcaatgt gcgaagaaat
     7801 gtgtaagaga aaaaattcag gacgatttta tctatttttt gatggttttt gcaagagcag
     7861 taaaaatggc ggtcaaaact aagagaatag attttattat aaatttttat aaatattata
     7921 ttcgaggatg aaatgatttc tgtttgtata ccaacttaca atggtgaata ttatattgaa
     7981 gagcaaattg atagcattct atcagagata ggccctgatg atgaaataat tatttcagat
     8041 gatggttcaa ccgattctac cttatctatc attgaggagt acaaggatcc ccgcattaag
     8101 gtttataaaa atagcataaa aaatataaat tatttcaaag atcgtactga gattctttta
     8161 aaaaaagtct ctttaaatgt gcaaaataca ttgatgcatt gtcaaggcga ctatatatat
     8221 ttagctgatc aggatgatat ttggataaaa ggacgtattg caaaaactat atcttttttg
     8281 aataccaatt ccccaacttt agtggtttgt aattgttctg ttattgatga agatcgtaac
     8341 gtaacacaag attcgtattt tgattatata agtccaagta gtaatatttt cagaactatg
     8401 gttaaaagtt catttcatgg gtgttgcatg tgtttcaacc gtagtttatt agataaatta
     8461 tttccttttc ctgaatatag cattggtcat gatctatgga ttggattaca ggcaatgaaa
     8521 tttaaagggg ttctttttta ttctgaaccg ttacttttat atcgcaggca ttcatctaca
     8581 gtaactatga ctggtaataa gagttctaat actcttaatt ttaaaatcaa atataggtta
     8641 atgatgttga aagaatattt gagaatagat aaaaaaagat gaagaaaatt gctcatgtta
     8701 tagttttacc aaaaatggca ggctcacaaa agttttgcca tgcgttactg tcaaaaatta
     8761 atggctataa aaaatatata ctagtttctg gctgtgaaaa tgttgatatt gatcagaggc
     8821 aagaatttat aaatgcgttt gaatctatca acgttgaaat catttggtgc tattatctta
     8881 aaaggaatat agggaaatca gatattagag gttttataga gctatataca atttttaaga
     8941 aataccaatt tgatatagtc catactaatt caactaaacc aggtatttta gccagaattg
     9001 ctgctcgtat gtctggcgta aagaaaattg ttcatacagt tcatgggatt tctttctaca
     9061 agggacaaaa tgttataaaa aggcttattt attgggcaat cgaatgtgtt gccttgcagt
     9121 ttggcgatat aaatgtttgc gttaataatt attacctgaa atattataaa aaattctttt
     9181 ggaaaaaaaa tataagtgtt tttaatggtt atgatttttc cgagttacta ttgtatgcga
     9241 atagtaataa tgttaaatgt aataataaaa aagataatgt tttctctttt ttatttgtgg
     9301 gaagactgga tatacaaaag gatcctataa cgctcataaa agctttctca atattggctt
     9361 caaaatatcc aaatataatt ttagatattg tgggtgatgg agaactaatg gaagcaagta
     9421 aagaactagc ttgtgagctc ggagtaaaag atttagtaag atttcatggt tggatcaaaa
     9481 aaccttattc gtatttttat aattgtaatg catttgtttg tccgtcatta tatgaggcgt
     9541 ttggtttcat ctttgtagaa gcagcatatt ttagaaaacc tataatagct actaatgttg
     9601 aaggcatacc tgaagtcgta ctcaataata aaatgggttt tttagtaagt ccatctaatt
     9661 atcttgcatt agctgaaaaa atggagatcc ttgtaaactc tcgaagcttg tgtaaggtta
     9721 tgggagattt cggtagccga tatgttatcg agaatttcga tatccagaaa tgcgtaaaag
     9781 cgtatcaaag tatttatgat aatgatttaa ggtaactaat gattagggtt tgtattaaaa
     9841 tttattttcc atattttatt tctgcactgt tatttttttg ttttttattt tattttaata
     9901 aaatggatgt gtttcctttt tttttagggg aatcgttttg tatatatgca actttattat
     9961 attttgaaaa aagaattata agaggaatta tatggtcatc gtttatggtg attgtaggat
    10021 ttcaaatggc atcgttatat acaagtggag atttaataat tccattgacg ctttctaatg
    10081 ctggcgagta caaggcatta ggatttaatt tacttattaa attatttttc attgtgttca
    10141 tttttttctt attttcgtta cctctatata gtcgagtgtt ttattgctat aatccttatt
    10201 ataaatttat gtgcctcatg gctgtatgtt tgccattgat taacgggcca ttattaatgt
    10261 ttggaaaaac attatacgcg tactaccagc aacttacttt ttcaccttcc tataattatc
    10321 ccgaaattgc aaaaaaatat ttaaaaattg gtatatggaa taatagttca tctcttctta
    10381 aagtaactaa acctaatata attataatat ttgctgaagg tatgtcctat agtgttatag
    10441 atagtgtaaa taataagggt ttgaaactta ccccaaatat agacactcta atggataatt
    10501 ctttggtttt taggaattac tataatcata ctgcagccac attccgtggg ttaagaggac
    10561 aattaacttc tgcatatcaa tataaggatg gtattggagc acacaatgac ggtttttttg
    10621 aaatatctaa tgaaaaagtt aaagcaactt ttgataaaag gctcgtttct ttacctgaga
    10681 tacttagctc atccggctac aaaactatct ttttatcatc cacggaaaaa aatagtactc
    10741 tcaatgcaat gctaaaaaca ttgtcttttg atgaagttta tggaatggga gattttgagt
    10801 tctatcaaaa cgatcgtatg actgataagc aaacattttt atcacttaag aaacttgttg
    10861 aaaaaaataa agggaataat ttttttatcg gtgtttatac ttcaggaaca catcatggta
    10921 tggatagtcc aaatttgcgc tataaagatg gtatgaattc atattacaat aagttttata
    10981 actttgatca tcaattaggg gagtttatta attatcttga ttctaatggt ttaatggaaa
    11041 atacattatt gataattaca gcagatcatg caacatttcc cactccagcg tttaataggg
    11101 cattcgacac ggatgctaaa tattttattg ataccatccc tcttataata tttggcgcag
    11161 ggataaaaca tcatatctat gatgctaagg gcgcaaatag tttagcattg gctccaacga
    11221 ttctaaatat actaaatatt aataaccgcc ctaattattt tctgggatgt tcactattag
    11281 atgttaaatg taatagccga ttttataata tttctgcaat tggaaattct ttctttatga
    11341 caggacctga aaagtatcct aattataatg ttaaagaact gaacgtttct gaagaaatct
    11401 tgaactttta taatgttagt ggttaatcag atgaaaacta tggtcatata ctattttttc
    11461 tgaaagataa gtgagttaac atctaagcca catttcaagc cgcgctctcg tcgcgcggtg
    11521 accacacctg acaggagtat gtaatgtcca agcaacagat cggcgtcgtc ggtatggcag
    11581 t
//
