LOCUS       JX975333               12848 bp    DNA     linear   BCT 27-AUG-2013
DEFINITION  Salmonella enterica strain G1603 O antigen gene cluster, complete
            sequence.
ACCESSION   JX975333
VERSION     JX975333.1
KEYWORDS    .
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12848)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Reeves,P.R. and Wang,L.
  TITLE     Structural diversity in Salmonella O antigens and its genetic basis
  JOURNAL   FEMS Microbiol. Rev. (2013) In press
   PUBMED   23848592
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12848)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Reeves,P.R. and
            Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2012) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..12848
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="G1603"
                     /db_xref="taxon:28901"
                     /note="serogroup: O63"
     misc_feature    1..12848
                     /note="O antigen gene cluster"
     gene            1106..2119
                     /gene="gne"
     CDS             1106..2119
                     /gene="gne"
                     /note="Gne"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-GlcNAc-4-epimerase"
                     /protein_id="AFW04727.1"
                     /translation="MLILVTGGAGYIGSHTIISLLENNYNVIVLDNLCNSSLESIKRV
                     EKITNKKIKFYLGDVRDKVFLESIFCDNKIDAVIHFAALKSVGESNNYPLDYYSNNVT
                     GTLSLLEVMKQFDVSKMIFSSSATVYGAKNIAPNKESDPIGGTTNPYGTSKYMMELIL
                     QDLCKSDPSFSIVSLRYFNPTGAHSSGMIGENPNDIPNNLIPYISKVAQKKLQKLHVF
                     GNDYPTKDGTGIRDYIHVSDLALGHVKALDYIFLNNINYEAFNLGTGRGYSVLEVVRM
                     FEKVSNTLIPFDFCERRNGDIAISWACADLARKKLNWETTRDLKEMLEDVWRWQVKNP
                     NGY"
     gene            2141..3157
                     /gene="weiD"
     CDS             2141..3157
                     /gene="weiD"
                     /note="WeiD"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04728.1"
                     /translation="MNNIAFIITKAEVGGAQKWVNEIAKLIKDDCRVFLITSEEGWLT
                     QSKNFSEVYLLPEIKKKFHLATYLKLINFIRRNNIRTIIASSANAGIYARMSKLFCKF
                     KCIYVSHGWSCLYNGGKLKWVFCEIEKYLSFLTDFVWCISESDKRKAIKEIGIKEKKI
                     ITITNAVPPMPITPRKLLENKVLFVGRLTHPKRPELIARVISKRPDYKLDIIGDGELL
                     ESLKTQFAHFENIRFLGEIKDFSNYQAYDVFALISDSEGLPMSALEAHTAGIPLLLSN
                     VGGCYELIEKNGLLVKNNECDINDKLNEIFSNYELFRSNAKNAIQKFDINNYSRLYKK
                     IIVD"
     gene            3464..4537
                     /gene="rmlB"
     CDS             3464..4537
                     /gene="rmlB"
                     /note="RmlB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase"
                     /protein_id="AFW04729.1"
                     /translation="MKILITGGAGFIGSAVVRHLIKDTQYTVINIDKLTYAGNLETLA
                     DIAESDRYYFEHEDICDAEAMARIFRQHHPDVVMHLAAESHVDRSIIRPTAFVETNIV
                     GTYVLLETARKYWSSLTDKKKAAFRFHHISTDEVYGDLPHPDEVAANTKLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWLRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KPLPIYGKGDQIRDWLYVEDHARALHIVVTQGVVGETYNIGGHNEKKNLEVVHTICDL
                     LDEIVPKEGSYRDQITYVTDRPGHDRRYAIDAGKISRELGWRPLETFESGIRKTINWY
                     LNNAEWCCRIRETGFQHGLLGLK"
     gene            4539..5414
                     /gene="rmlA"
     CDS             4539..5414
                     /gene="rmlA"
                     /note="RmlA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="AFW04730.1"
                     /translation="MKGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLSVLMLA
                     GIQDILIITTPEDQAAFIRLLGNGKQFGINLSYEIQPNPDGVAQAFILGENFIAQDSV
                     CLVLGDNIFFGQGFTPKLRSAAERKNGATIFGYQVMDPERFGVVEFNNKFKAVSIEEK
                     PTHPKSNWAVTGLYFYDNDVIEIAKSIKPSTRGEIEITSVNEIYMNNDCLTVEILGRG
                     FAWLDTGTHDSLIEAGSFVETVQKRQGMMVACPEEIAWRNGWLSGDDVYNLGKSIQKN
                     SYGQYLINLVKKNEY"
     gene            5404..5799
                     /gene="fdtA"
     CDS             5404..5799
                     /gene="fdtA"
                     /note="FdtA"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-3,4-keto-hexulose isomerase"
                     /protein_id="AFW04738.1"
                     /translation="MNIEIIPFQKHGDERGMLVALEQIKNVPFEIKRIYYMFGTKQNV
                     RRGFHAHKNLRQLAIAVCGQCTFLLDDGDEQKTILLNDPEKGLLIEPGIWHEMFDFSD
                     DCILLVLASDIYDECDYIRDYDEFQEWTK"
     gene            5796..6251
                     /gene="fdtC"
     CDS             5796..6251
                     /gene="fdtC"
                     /note="FdtC"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-Fucp3N acetylase"
                     /protein_id="AFW04731.1"
                     /translation="MNYNQFSDVQSKNIGEGTRVWQFSVILPGAVIGAECNICAHTLI
                     ENDVVIGDRVTIKSGVYIWDGITLEDDVFIGPCVSFTNDKIPRSKQYPEQFARTVVKK
                     GASIGANATILPGIVIGEGAMVGAGAVVTKDVPANMVVIGNPAKNIKEV"
     gene            6254..7357
                     /gene="fdtB"
     CDS             6254..7357
                     /gene="fdtB"
                     /note="FdtB"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-xylo-hex-3-ulose aminase"
                     /protein_id="AFW04732.1"
                     /translation="MVDFLDLKKINNKYEKELKEACARVIDSGWYIMGQELVSFEKEY
                     ESWCGVKHAIGVANGLDALTLVLRAWKELGRLKNNDEVIVPANTYIASILAVTLNNLT
                     PVFVEPELETFNIDVTRIERAITDKTKAILPVHLYGQICSMEKIRDLAVKYNLLVLED
                     CAQAHGASIDKIKAGRWGDAGAFSFYPGKNLGAIGDAGLITTNDDVLAETLRALRNYG
                     SHRKYENIYQGFNSRLDEIQAAMLMVKLKYLDSDNNIRKAIAHKYNSEIKNPLISLPF
                     CPNDESHVWHLYVIKCKHREALQSYLAINNIQTLIHYPIPPHKQKAMNFYRSLSLPIT
                     EEIHKCVLSLPISPVMELSEVKKVIDCVNNFNI"
     gene            7354..8634
                     /gene="wzx"
     CDS             7354..8634
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AFW04733.1"
                     /translation="MRNLLSVTFFSGMLTLTRMMSGFVIAKVISVYTGPTGLALLSQL
                     QNFNSIATGLLTSSVNQGVVRYTAENKNRSFKECSQWWKGGLAISLTIVSIFSPIILL
                     FAPSITHFLLGDKKLYPYVIVVIIISPFSILGTLMLSVLNGLQQYRRYIMISIVSVIM
                     SCVMMVLLIQSYGVNGALISASIQNGVIGAIVLIFVSRQPWFKLNLFLGRIDKRHFLG
                     MSSYTLMAIVSAIALPFTQIAIRYIMVNKIGWDRMGQWQAVWKISEVYLSVITISLST
                     YFLPKLATLTSMAQIQGEIKSVSKIVLPVVIIMALCIYFLRDLIITILFTEHFTESHR
                     YFAVQLIGDVVKIMSWLYAYPMISRGMVKIYICTEIIFSILLILLSYFLINIYGAHGA
                     NYAYLITYLIYFFAIFSFMHHLTRRELNENFAGR"
     gene            8612..9730
                     /gene="wdcO"
     CDS             8612..9730
                     /gene="wdcO"
                     /note="WdcO"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04734.1"
                     /translation="MKILLVGEFSGVHTHLSKALKDMGHIVTTISDGDAYKNFPRDIT
                     IPLNKNTSKWAVLKDYIYDYLGIKGLFLYFKKRKTLSELRGFDIVQLINPAPIAAFGS
                     LASLLLLKKLERNNNKLFLCALGDDYRWVSACLSGTYKYSALDNLSVKTFPKYLYTLK
                     YKYGFFYKTLHLLTEKKCRAIIPGLYDYQLAYNGHPKITDIVKLPIEPLKNESSTNAQ
                     GKNNRVVIFHGWQVGKEFRKGNFIFDAAMQIILKKYGEERVQYIVCKSVPYSDYILLV
                     SQADLFLDQVYSYDFGVNALLGMKYSSVVLSGFECYSDGIGINVEPELSALVEKISFL
                     IENPLIVEDIKTKARSHVKIHHDAMSVSRKYLEIWEKY"
     gene            9730..10674
                     /gene="wzy"
     CDS             9730..10674
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AFW04735.1"
                     /translation="MINKNRYKGYYLILSFFLTLIFALRFFYFSHYEILLVSDTLEYY
                     NNFSDIENDLFPYGLEILMPILMFFIKAIGGNFYDFLFFVLTLWLPLIFIIIYRSCYN
                     PLFFIIVFISSFFYMNAVLIIRQYISGVFFIYCMLFAYQHKKISLFLAFLSILSHSYA
                     IVWLIVVGRWFRNFITNKIILSVIIPISLFAVSFSFSSYQLQSVSSFLLQYNMPGLLQ
                     RKIQYYNNNNDPVESVSNISLILVDIIFILSIINLLKQKNEFVLKLSSLLIFNSFCFI
                     MLGSNIVSASRFGFWSYYFSIPSLVILLYYCLNLVKDK"
     gene            10676..11437
                     /gene="wdcP"
     CDS             10676..11437
                     /gene="wdcP"
                     /note="WdcP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04736.1"
                     /translation="MQINVYVISLEDEFLRRNIMREQLNGPFTFINAVDLRKIKSITI
                     TKYLNNDKLPYPKVRTNLTNGEIGCALSHLKALNKFVEDEGEYALILEDDAILPTNYL
                     DVINNICSNSKGYWDFLLLGYSKLDVSETSSFYKMEPINILQKINNISIGEPWKNWTS
                     GTVAYLVSKQAARRFIEVHNRKIFTVADDWAFFKGNFDFKILHCRPLIIFENYAELKS
                     SIELERGTFISYTPYYLKFIRICRGYIRKLFMLMR"
     gene            11440..12537
                     /gene="wdcQ"
     CDS             11440..12537
                     /gene="wdcQ"
                     /note="WdcQ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04737.1"
                     /translation="MNILLVITGLGLGGAEKQVCLLADQFAARGHKVGIVSLTNKTDV
                     KPSNPEVELFILDMKKNVLGFIGTIKRLRVIANNFNPDVIHGHMFHANIMVRFLNALT
                     TRKNKIISTAHNKYEGGALRKCLYRLTDPFNHITTNVSQEALDKFIADKVFLKKKSFT
                     VYNGIDTNYFKFNNNARSYLRQSLNVSEQDILLLAVGRLTEAKDYPNLIKAFKKTPSN
                     YKLIIIGEGDAEAAILKIIENNNLSLRIKLLGVKNNVRDYYSASDIFVLSSAWEGFGL
                     VVAEAMSCERIVIATDSGGVKEVIGNPEFLVPIKNPDALAKKIIDISKLNSSYKEIIC
                     KKNRSFIVDNFSIDNTISKWLHIYKSLNSTI"
BASE COUNT     4101 a   1852 c   2537 g   4358 t
ORIGIN
        1 attgtggctg cagggatcaa agaaatcgtt ctggtgactc atgcgtctaa aaacgccgtt
       61 gagaaccact tcgacacctc ttatgaactt gaatcacttc ttgagcagcg cgttaagcgc
      121 cagcttctgg cggaagtgca atctatctgc ccgccgggcg taactatcat gaacgttcgc
      181 caggcgcagc cgttaggatt ggggcactct attctgtgcg cgcgtccggt ggtgggtgat
      241 aatcctttca tcgtagtact tccggatatt attattgatg atgctaccgc cgatccgctg
      301 cgctataacc ttgcggcgat ggtggcgcgc ttcaatgaaa cgggtcgcag tcaggtactg
      361 gcgaagcgca tgaaaggcga tttatcggag tattctgtta ttcagacgaa agaacctctg
      421 gataatgaag gcaaagtcag ccggattgtg gaatttatcg aaaaaccgga tcagccgcag
      481 acgctggact ccgatttgat ggcagtaggc cgttatgtgc tttcagccga catctgggcg
      541 gaattggaaa gaaccgaacc gggcgcctgg ggccgcatcc agctcacgga tgccattgct
      601 gagctggcga aaaaacagtc ggttgacgca atgctgatga cgggcgacag ctatgactgc
      661 ggtaaaaaaa tgggctacat gcaggcattt gtgaaatacg ggctgcgtaa cctgaaagaa
      721 ggggcgaagt tccgtaagag catagagcag ctattgcatg aataagtatt aacaactgtg
      781 ataaatggtt ggttataaaa ataataacgg cggtgaacat tctaaatggc atggttgctg
      841 aaagggtgtt tactgccgtt ttagttttgg ataaagggct ttagtaacaa ggggttatct
      901 ggagcatttt aatgctgatt ttataagatt tatccttgtt tccggatgca attgataaga
      961 caattagcgt ttaagtttta gtaatctttg ccctgggtga gcgaaggttg tgacagattg
     1021 atatatacgc agtgcactgg tagctgatga gccaggggcg gtagcgtatt taaataagtt
     1081 actagtcttt tgcaggagac aaaagatgtt gattttagtt actggtgggg cgggatatat
     1141 aggttcacat actataatat cgctgttaga aaataattat aacgtcattg tgcttgataa
     1201 tttatgcaat tcatcattgg aatctataaa gcgggttgaa aaaataacta acaaaaaaat
     1261 aaaattttat ttaggagatg ttcgtgataa agttttttta gaaagtattt tttgtgataa
     1321 taaaattgat gcagttatac attttgccgc attaaagtct gttggagaat caaataatta
     1381 tcctttggat tattattcta ataatgtaac agggacactt agcttacttg aagtaatgaa
     1441 acagtttgat gttagtaaaa tgatatttag ctcatcagct acagtttatg gggctaaaaa
     1501 tattgcacct aataaggaga gtgatcccat agggggaaca actaatcctt atggaacatc
     1561 aaaatatatg atggagttaa ttcttcaaga cctttgtaag agtgacccaa gtttctcaat
     1621 tgtttcttta agatacttta atcctactgg tgctcattcc tcagggatga ttggggaaaa
     1681 tcccaatgat atacctaata atcttatacc ttatataagt aaggttgcgc aaaaaaaatt
     1741 acagaagtta catgttttcg ggaatgatta tcccacaaaa gatggaacag gcattagaga
     1801 ttatatacat gtttctgact tggctttagg ccatgtaaaa gcattagatt atattttttt
     1861 aaataatatt aattatgagg cattcaattt aggtactggt cgtggatatt ctgtacttga
     1921 agtagtacgt atgttcgaaa aggtttctaa tacattaatt ccatttgatt tttgtgaaag
     1981 gcgaaatgga gatattgcaa tatcttgggc atgtgctgat ttggcaagaa aaaaattaaa
     2041 ttgggaaaca acaagagatt taaaagaaat gttggaagat gtttggcgtt ggcaagtaaa
     2101 aaatccaaat ggctattaaa ttaccaggtt atgacatctc atgaataata ttgcatttat
     2161 cattacgaaa gcagaagttg gtggcgctca aaaatgggtt aatgaaatag ctaaactaat
     2221 taaggatgat tgcagagtat ttcttatcac ctcagaagag gggtggttaa cccaaagtaa
     2281 aaatttttca gaagtttatt tgcttcctga gataaaaaaa aaatttcatt tggctactta
     2341 tttaaaatta ataaacttca ttaggagaaa taatataaga accatcatcg caagttctgc
     2401 aaatgctgga atatatgcac gaatgtcgaa attattttgt aagttcaagt gtatttacgt
     2461 ttcgcatgga tggtcatgtt tgtataatgg tggtaaatta aaatgggtgt tttgcgagat
     2521 agagaaatac ctttcctttc taacagattt tgtatggtgt atttcggaga gtgataagag
     2581 gaaggctata aaagagattg gtattaaaga aaaaaaaata atcacaatca ctaacgctgt
     2641 tcctcctatg cctataactc caaggaaatt gttagagaat aaagtgcttt ttgttggtcg
     2701 tttaacacac cctaaacgtc cagaacttat tgctcgagtt atatctaaaa ggccagatta
     2761 caagttggat attatcggag atggcgagtt acttgaatct ctaaaaactc aatttgcaca
     2821 tttcgagaat ataagatttc taggcgaaat taaagatttt tctaactatc aggcttatga
     2881 tgtatttgct ttaatttctg atagtgaggg gttaccgatg tcggcacttg aagcgcatac
     2941 ggcaggcata ccgcttcttc taagcaatgt tggtggttgc tatgaattga ttgaaaaaaa
     3001 tggattatta gtaaaaaata atgaatgtga tatcaatgat aaattaaatg aaatattttc
     3061 aaattatgaa ttatttcgtt cgaatgctaa aaatgcaatt cagaagtttg atattaataa
     3121 ttattcgcgg ttatataaga aaattattgt ggattgaaat taatatttga atcgttattt
     3181 tgcttattat tatcattaac tttttgtagc gtttattttt tgctgaaata tggatttgtt
     3241 ttacagatga aacgtagttt attaaataaa atcgcaagac ggctatattt aatttattta
     3301 agaataatat ttatattata gaaactattt tttctgagca aaaagttaga tgctaaatgt
     3361 cgggtggctg ttaaaatgga tatagcagtt gtcagggatt tagatatatt aatctttggg
     3421 ggggtgattt taactagaac actcttctta tttggtgtga aatatgaaaa tacttattac
     3481 tggtggggcg ggctttattg gttctgccgt tgttcgtcat cttatcaaag atactcaata
     3541 tacagtcatt aatattgata aattaactta tgctggtaac cttgaaactc ttgctgatat
     3601 agctgagagt gatcgctatt attttgagca tgaggatatt tgtgacgccg aagcgatggc
     3661 gcgtatcttt agacagcatc atcccgatgt ggtaatgcat ttagccgcgg aaagccatgt
     3721 tgatcgctct attatcaggc cgaccgcttt tgttgaaacc aatatcgtag gtacgtatgt
     3781 actactggaa actgcgcgca aatactggtc ttctttaacg gataagaaaa aagcagcatt
     3841 tcgttttcat cacatttcca ctgatgaagt ctatggtgac ttaccgcatc cggatgaagt
     3901 tgcagctaac accaagttac cgttgtttac cgaaaccacc gcctatgcac caagtagccc
     3961 atattccgcc tctaaagctt caagcgatca tttagtccgt gcttggctgc gcacctacgg
     4021 cctgccaact atcgttacca attgttctaa caactatggt ccgtatcact tcccggagaa
     4081 actcattcct ctggtcattt tgaatgcact ggaaggtaaa cccttgccca tctatggcaa
     4141 aggcgaccaa attcgtgact ggctgtatgt ggaagatcat gcgcgtgcgc ttcatatcgt
     4201 ggtgactcag ggcgtagtgg gtgaaaccta taatattggt ggtcataatg agaagaagaa
     4261 ccttgaggta gtccatacta tctgtgattt gttagatgaa attgtaccga aagaaggttc
     4321 ttaccgtgac caaattacat atgtgactga ccgtccaggg cacgatcgcc gctatgctat
     4381 tgacgctggt aaaattagtc gtgaacttgg ttggaggccg ttagaaacat ttgaaagtgg
     4441 tattcgcaaa actattaatt ggtatttaaa taatgctgaa tggtgctgtc gaattagaga
     4501 gactggcttt cagcatggac tattaggatt gaaataaaat gaaaggtatc attttagctg
     4561 gaggttcagg tactcggttg tatcctatca ccatggggat atcgaagcaa ttattacccg
     4621 tttatgataa accaatgata tattatcctt tgtcggtatt aatgcttgct ggtattcagg
     4681 acatattaat tataactact ccagaagatc aggctgcctt tattcgattg ttaggtaatg
     4741 gtaaacaatt tggcattaat cttagttatg aaatccagcc aaatccagat ggggtagcgc
     4801 aagcatttat tttaggtgaa aattttattg cccaagattc tgtttgtctc gtgcttggcg
     4861 ataatatttt ttttggtcaa ggatttacgc ctaaacttag gtctgcagcg gaacgaaaaa
     4921 atggtgccac tatttttggt tatcaggtta tggatcctga gcgttttgga gtagttgagt
     4981 ttaacaacaa atttaaagcc gtaagtatcg aagaaaagcc tactcatccg aaatcaaact
     5041 gggctgttac tggactgtat ttttatgata acgatgttat tgagatagct aaatcaataa
     5101 aaccgtctac tcgaggcgaa atagaaatta catcagtgaa tgaaatttat atgaataatg
     5161 attgtttgac tgtagagatt ttaggccgag ggtttgcatg gcttgatact ggtacacatg
     5221 atagcttaat tgaagctggt agttttgttg aaacagtgca aaaaagacag ggaatgatgg
     5281 tggcttgtcc ggaggaaata gcttggcgca atggttggtt gagtggcgat gacgtttata
     5341 atttaggtaa aagtattcag aaaaattcgt acggccagta tcttatcaat ttagtgaaaa
     5401 aaaatgaata ttgagataat tccatttcag aaacatggcg acgagcgagg aatgctggtt
     5461 gcacttgaac agattaaaaa tgttcctttt gagataaaac gaatttacta catgtttggt
     5521 accaaacaaa atgttcgcag aggattccat gctcataaga atttgcgtca actcgctata
     5581 gctgtatgtg gtcaatgtac ttttctgtta gatgatggag atgaacagaa aactatactt
     5641 ttaaatgatc ctgaaaaagg cttgttaata gagccaggaa tatggcatga aatgtttgat
     5701 ttttcagatg attgcattct tttagtttta gcaagcgata tttacgatga atgtgattat
     5761 attagagatt acgatgaatt tcaggaatgg actaaatgaa ttataaccaa ttcagtgatg
     5821 tgcaatctaa aaatataggt gaaggaacga gggtatggca gttttctgtt attctgccgg
     5881 gagcggtaat tggtgcggaa tgtaatatat gtgcgcatac tttaatagag aatgatgtcg
     5941 ttatcgggga tagagtcact ataaaatcag gtgtatacat ttgggatggc attacacttg
     6001 aagatgatgt ttttattggc ccgtgcgtat cgtttactaa tgacaaaatt ccccgttcaa
     6061 agcaataccc agaacagttc gcccgtacag ttgtaaaaaa aggtgcttct ataggtgcaa
     6121 atgcgacaat attgcctgga attgtcattg gagagggggc aatggtcggt gcaggagctg
     6181 ttgttactaa agatgtacca gcaaatatgg ttgttattgg aaatccagca aaaaatatta
     6241 aggaagttta attatggttg attttttgga tctaaaaaaa attaataata aatacgaaaa
     6301 agagttaaaa gaagcctgtg ctcgagtaat tgattctggt tggtatataa tggggcagga
     6361 gctagtttct ttcgaaaaag agtatgagag ttggtgtggc gtaaaacatg ctatcggtgt
     6421 ggcgaatggt ctagatgctc tgaccttagt tttgagagct tggaaagaat taggtagact
     6481 taaaaataat gatgaagtta tcgttcctgc taatacttat attgcctcaa tacttgcggt
     6541 tacattaaat aatcttaccc ccgtatttgt agagccggaa cttgaaacat ttaatattga
     6601 tgtcactcga attgaaaggg ctatcactga taaaacaaaa gccattttgc ctgtgcattt
     6661 atatggacaa atttgttcta tggaaaaaat ccgcgatctc gcggtaaaat ataatttgtt
     6721 ggtgcttgaa gattgcgcgc aagcacacgg tgccagtata gataaaatca aggctgggag
     6781 atggggtgat gctggagcgt ttagttttta tccaggtaaa aacttaggtg caattggcga
     6841 tgcaggctta atcacgacaa atgatgatgt attggccgaa acgttaaggg cattgcgaaa
     6901 ctatggttct catcggaaat acgaaaatat ttatcaagga tttaatagca gacttgatga
     6961 aatacaagct gcaatgctaa tggttaaatt aaaatatctt gattctgata acaatatcag
     7021 aaaagcgatt gctcataagt ataatagtga gataaaaaac ccattaatca gtttaccttt
     7081 ttgtccaaat gatgagagcc acgtatggca tctatatgtt ataaaatgca aacatagaga
     7141 ggctttgcaa agttacttgg caattaataa tattcagact ttgattcatt atccaattcc
     7201 acctcataaa caaaaggcga tgaattttta tcgttcgcta tctttaccga taacggaaga
     7261 aatacataaa tgtgttcttt cattacctat tagcccggta atggaattat ctgaagttaa
     7321 aaaagtaatt gactgtgtca ataatttcaa tatatgagaa atttattatc tgttactttc
     7381 ttctccggca tgttgacctt aacaaggatg atgtcgggat ttgttatcgc aaaagtgatt
     7441 tctgtttata ccggaccaac aggattggct ctgctatcgc agttacagaa ttttaacagt
     7501 attgcaactg gactattaac gtcatctgtt aatcagggag tggttcgtta tacggccgaa
     7561 aataaaaata gaagttttaa agaatgttct caatggtgga aaggggggct ggctataagt
     7621 ttaacaatag ttagcatttt ttcaccgata atattattat ttgctccttc tataacacat
     7681 tttttattag gtgataaaaa gttataccca tatgttatag tagtcattat tatttcacct
     7741 ttttctatat tgggaacttt aatgctatca gtacttaatg ggcttcaaca atatcgacga
     7801 tatataatga ttagtattgt ttctgtgata atgtcatgtg taatgatggt gttattgatt
     7861 cagagctatg gggtgaatgg cgcattaata tcagcttcta tacaaaatgg tgttataggt
     7921 gcaatagttc tcatttttgt aagcaggcaa ccttggttta aattaaattt atttcttgga
     7981 cggatagata aaagacactt tttaggcatg tcgagctata ctcttatggc tatagttagt
     8041 gccattgcct taccttttac gcaaatagct attagatata tcatggttaa taaaattggc
     8101 tgggatagga tggggcaatg gcaagcagta tggaaaattt ctgaagtata tttaagtgtt
     8161 attactatat cgctaagcac ttattttcta ccaaagcttg caacattaac ttctatggca
     8221 cagatacagg gagaaataaa atctgttagt aaaatagttt taccagtagt aattattatg
     8281 gctttgtgca tttactttct aagagattta ataattacca ttttatttac ggaacatttt
     8341 actgagtctc ataggtattt cgcagttcaa ttaattggag atgtcgttaa aataatgagt
     8401 tggttatatg cttatccaat gatatctcgt ggtatggtaa aaatatatat ttgtacagaa
     8461 attatttttt caatcttgtt aattttatta tcttattttt tgataaatat ttatggtgcc
     8521 cacggtgcaa actacgccta cttaattaca tatttgatat atttttttgc aatattctct
     8581 tttatgcacc atttaacaag gcgagaatta aatgaaaatt ttgctggtcg gtgagttttc
     8641 tggcgtacat actcatttat ctaaagcatt aaaagatatg ggccatattg taacaactat
     8701 ttctgatgga gatgcgtata aaaactttcc aagagatata actataccgc taaataaaaa
     8761 tacaagcaaa tgggcagttt tgaaagatta tatttatgat tatttaggta tcaaaggact
     8821 atttttatat tttaaaaaaa ggaaaactct ttcagaacta agaggttttg atattgtaca
     8881 acttatcaat ccggctccaa tagctgcttt tggatcttta gctagtttgc ttcttttaaa
     8941 aaaattagaa agaaataata ataaactttt tttatgcgcc ttaggagacg attatcgctg
     9001 ggtaagcgct tgtttaagtg gtacttataa atatagtgcg ttggataatc tttcagttaa
     9061 aactttcccg aaatatttat atacattaaa atataagtat ggtttctttt ataagacttt
     9121 gcacttatta actgaaaaga aatgtagagc tatcatccct ggactttatg actatcaact
     9181 tgcctataac ggccatccta aaattactga tattgtaaaa ttgcctattg agccattaaa
     9241 aaatgaatct agtactaatg cgcagggtaa aaataataga gtagtgattt ttcatggttg
     9301 gcaagttggt aaagaattca gaaaaggtaa ctttatattt gatgccgcaa tgcagataat
     9361 tttaaaaaaa tatggagaag aaagagttca atatatagtt tgtaagtcag taccttattc
     9421 agattatatt ttactcgttt cacaagcaga tctattttta gatcaagttt acagctatga
     9481 ctttggtgtt aacgctctat tgggcatgaa gtattcttca gtagtgttat ctggttttga
     9541 atgttattcg gatggcatcg gtattaatgt ggagccagaa ttatctgctc ttgtagaaaa
     9601 aatatcattt ttaatcgaga atccactcat tgtcgaggac ataaaaacaa aggctcgatc
     9661 tcatgttaaa attcatcatg atgccatgag tgtatcaagg aagtatcttg agatatggga
     9721 aaaatattaa tgataaacaa aaatcgatat aaaggctatt atttaattct ttcgtttttt
     9781 ctgacattaa tttttgcact tcggtttttt tatttttccc attatgagat attattggtc
     9841 agtgatacct tagagtatta taataatttt tctgatatcg aaaatgattt attcccatat
     9901 ggcttagaaa tattgatgcc aattttaatg ttttttataa aagcgatagg gggaaatttt
     9961 tatgactttt tattctttgt tttaacacta tggctcccgt tgatttttat tattatttat
    10021 agaagttgct ataacccatt atttttcata atagttttta tttcttcgtt cttttatatg
    10081 aacgctgtat taattattag gcaatatatt tctggggttt tttttattta ttgtatgctt
    10141 tttgcgtatc aacataaaaa gatatcctta tttttagcat ttttatcaat cttatctcat
    10201 tcctatgcaa tagtatggtt aatagttgtc ggacgttggt ttagaaattt tatcaccaat
    10261 aaaattattt taagtgttat tataccaata tcattatttg ctgtaagctt ctcattttct
    10321 tcttatcaat tgcagtcagt ttcttccttt ctcctccaat acaatatgcc aggtttgtta
    10381 caaaggaaaa tacaatatta taataataat aatgatcctg tagagtcagt ttcaaatata
    10441 agtttgattc ttgttgatat tatatttata ttaagtataa taaacctttt gaaacaaaaa
    10501 aatgaatttg ttttaaagtt atcatctctc ctaattttta attccttttg tttcattatg
    10561 cttggttcaa atattgtttc agcgagtcgt tttggctttt ggtcatacta tttttcaata
    10621 ccttcattag taatactatt gtattattgt cttaatcttg ttaaagataa ataaaatgca
    10681 aataaacgtt tatgttatat ctcttgagga tgagtttcta cgtagaaata taatgcgtga
    10741 gcaattaaat ggaccattta catttataaa tgctgtagat cttcgaaaga ttaaatcaat
    10801 tacaatcact aaatatctta ataacgataa attaccttat cctaaggtac gaacaaattt
    10861 aactaatgga gaaataggct gtgctcttag tcatttaaaa gctttaaata aatttgtaga
    10921 ggacgaggga gaatatgctc ttatacttga ggatgatgct atactgccta ctaactattt
    10981 agatgtaatt aataatattt gttctaattc aaaaggttac tgggattttc tacttttagg
    11041 ttattcgaaa cttgatgtaa gtgaaacatc atctttttat aaaatggaac ctattaatat
    11101 tttacaaaaa attaacaaca ttagtattgg tgaaccttgg aaaaattgga cttcaggtac
    11161 tgttgcttat ttagtaagta agcaagcagc acggcgtttt atcgaagttc ataatagaaa
    11221 aatatttact gttgctgatg attgggcttt ttttaagggg aactttgatt tcaaaattct
    11281 acactgccga ccactgatta tatttgaaaa ttatgctgaa ttaaaaagtt caattgaatt
    11341 agaaagaggt acttttatct cttatactcc ttattattta aaatttatac gtatctgtcg
    11401 aggatatatt cgaaaactgt ttatgttaat gagataacca tgaatatttt actagtaatt
    11461 acaggtttag gtctgggcgg agctgaaaag caagtttgcc ttttagccga tcagtttgca
    11521 gctcgtggtc acaaagtggg gatcgtttca ttaactaata aaactgatgt taaaccaagc
    11581 aatcctgagg ttgagttatt tattcttgac atgaaaaaga atgttttagg atttatcgga
    11641 acaattaagc gtctgcgtgt catcgctaat aatttcaatc ctgatgttat acacggtcac
    11701 atgtttcatg ctaatattat ggtacgtttt cttaatgctt taacaacaag aaagaataaa
    11761 ataatttcca ctgcacataa taaatatgaa ggaggcgctt tacgcaaatg tttatatagg
    11821 ttaactgacc ccttcaatca tataactaca aatgttagtc aagaagcatt agacaaattc
    11881 atcgctgata aagtctttct gaaaaaaaaa tcctttactg tttataatgg tattgatact
    11941 aattatttta agtttaataa caacgctagg agttatctta gacaaagttt aaacgtgtca
    12001 gaacaggata ttcttttgct tgcagtcgga agattgacag aagcgaagga ctatccaaat
    12061 ttaattaaag cattcaaaaa aactccaagc aattataaat tgattattat aggcgaaggg
    12121 gatgctgagg cggctatact gaagattata gaaaataata atctttcttt aagaattaag
    12181 ctattaggag ttaaaaataa tgtaagggat tattattctg ccagtgatat ttttgttctt
    12241 tcttctgcat gggaagggtt tggcttggtt gtcgctgaag ctatgtcttg tgaaagaata
    12301 gttattgcaa cagattcagg tggtgttaaa gaggttattg gtaatccaga gtttttagtg
    12361 ccgatcaaaa atccagacgc cttagcgaaa aaaattattg atatttccaa attgaactcc
    12421 agttataaag aaattatctg taaaaagaat agaagtttta tagttgataa cttttctatc
    12481 gataatacta tcagtaaatg gcttcatatc tataagagtc ttaatagtac tatttaatat
    12541 aatctaattg ttattagatt tattcttgag tttttcatcc atacaagtta cattacagcg
    12601 tttaatatat aatgtatttt gaggtttaaa ttttgattta acgtaatgtt tgttgacagt
    12661 taatttgatg ttggtatttt ctttgttttc caatttttac tggtgataaa ataaattggc
    12721 ttttacttat ctgccccttt gaattaaata aacataatat ttattttgaa ctatatattg
    12781 ttttatagta tccccaacag gagtatgtaa tggccaagca acagatcggc gtcgtcggta
    12841 tggcagtg
//
