LOCUS       JX975329               12707 bp    DNA     linear   BCT 27-AUG-2013
DEFINITION  Salmonella enterica strain G1445 O antigen gene cluster, complete
            sequence.
ACCESSION   JX975329
VERSION     JX975329.1
KEYWORDS    .
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12707)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Reeves,P.R. and Wang,L.
  TITLE     Structural diversity in Salmonella O antigens and its genetic basis
  JOURNAL   FEMS Microbiol. Rev. (2013) In press
   PUBMED   23848592
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12707)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Reeves,P.R. and
            Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2012) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23 Hongda Street, TEDA, Tianjin
            300457, P.R. China
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..12707
                     /organism="Salmonella enterica"
                     /mol_type="genomic DNA"
                     /strain="G1445"
                     /db_xref="taxon:28901"
                     /note="serogroup: O65"
     misc_feature    1..12707
                     /note="O antigen gene cluster"
     gene            113..1249
                     /gene="wejN"
     CDS             113..1249
                     /gene="wejN"
                     /note="WejN"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04678.1"
                     /translation="MKKILFISMNLGKCDYGGALVSNGNLFALKALNKYNVYAVSISK
                     NYSDNISKHIEFSILGSKNKVSTALSNLVGYAGRMNFRAMKEVISLIENVKPDIIYLD
                     SSLLGKIAKICKKKYKDIFIITFFHNVEIDFEFARVRAGRIQFLPSLIATSFAEAEAV
                     KNSDKIIMLHQKDSLRLKEKYGREADYFVPVCIKNSVDKKNAKLTFTKKEKDVIRVGF
                     IGTAFFANVDAVKIIANEIAPKVLNIAHFYICGKGFEKYKTLESSNISVSGYIESLDN
                     FYNDIDIMIFPIYSGAGMKVKIAESLMYNKSIIATPFALIGYEKIIDGVNVVQCESSE
                     SFIFQLKNTYCRHDSIYSRDAYLKYFSEESCHFYFEKIFNDIEL"
     gene            1288..2391
                     /gene="wejO"
     CDS             1288..2391
                     /gene="wejO"
                     /note="WejO"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04679.1"
                     /translation="MKILQVSKFYPPIFGGIEQVALDITMGMAEKNIPIDVLSVNNGP
                     KTTVENNIMRAALFFTFLSTPFSVSYVLMWRKIRNNYDIIHVHLPNPVAVLALLLFPP
                     RAPIIVHWHSDIVKQKIALKFFKPFQKLFLKKAKKIIVTSEIYGRSSPQLNGFRDKIV
                     CVPIGIQSNRLPDNELLLSSLKNKYKNKKIVFSLGRLVYYKGFESLIKAAAYLSDDVM
                     ILIGGEGELYEELYRSIVNNKLEDKVVLLGAIQHQDLAAYYKLCDLFCLPSIHESEAF
                     GVVQLEAMSYGKPVVSTNIKKSGVPWVNKNGVSGLVVNPNDPRELASAISAVLERACD
                     FSIGAFDRYKELFTRDKMIVNLLDIYINLNESK"
     gene            2398..3822
                     /gene="manC"
     CDS             2398..3822
                     /gene="manC"
                     /note="ManC"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphorylase"
                     /protein_id="AFW04680.1"
                     /translation="MILPIILAGGSGSRLWPLSRTLYPKQFLCLKGDLTMLQTTICRL
                     NGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAAARQH
                     TDCDPLMLVLAADHAIANEGAFRDAVRSAMPYADAGKLVTFGIVPDLPETGYGYIRRG
                     DAVPGATDAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRP
                     DILAACEQAMRGVDPDLDFIRVDEEAFLACPQESIDYAVMERTADAVVMPMDAGWSDV
                     GSWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVL
                     IADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGE
                     GLSVQMHHHRAEHWVVVAGTARVTINGEVKLLGENESIYIPLGATHCLENPGKIPLDL
                     IEVRSGSYLEEDDVVRFEDRYGRV"
     gene            3933..5321
                     /gene="manB"
     CDS             3933..5321
                     /gene="manB"
                     /note="ManB"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="AFW04681.1"
                     /translation="MTKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPQTIVLG
                     GDVRLTSESLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVNDAARGSYRQITLRDAYIDHLL
                     GYISVKNLTPLKLVVNSGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIP
                     NPLLPECRDDTRNAVIEHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLE
                     KHPGAKIIHDPRLTWNTEAVVTAAGGTPVMSKTGHAFIKERMRLEDAVYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGQSLGGLVADRMATFPASGEINSRLAEPAAAIAR
                     VERHFAGEALAVDRTDGISMSFADWRFNLRSSNTEPVVRLNVETKKNNELLNKQTAFV
                     ISLLRNKNNDTK"
     gene            5308..6273
                     /gene="wejP"
     CDS             5308..6273
                     /gene="wejP"
                     /codon_start=1
                     /transl_table=11
                     /product="WejP"
                     /protein_id="AFW04682.1"
                     /translation="MIRSNDITFVVQGPIRDATKETLKSIRLNFKESIIILSTWEGSD
                     VQGLDFDTVIYNKDPGSLDIRKNKIVVSQENTNRQIVSTHHGLIKVKTQYAVKLRTDM
                     PILNTNIIKYYKKAQCYESDINFTLLEERVLVSSINTIDPNSYIKFPYHISDWIYFGK
                     TSDLLKIWNGELVPNDEYFTEQNIKEEVCCERGFDFGRFTAEQLVLYSFLRKNRINDY
                     NFYCDVNEYKIEKAIKYTLSNFYCVSPKKLGVCFNKYEDLINIKMSYNSLRHYFGFYL
                     VTINESVWRNYYSKYYSLKTSITEKLEINIRRLALHFMRKLKHEK"
     gene            6263..7381
                     /gene="wejQ"
     CDS             6263..7381
                     /gene="wejQ"
                     /note="WejQ"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFW04683.1"
                     /translation="MKNRLLYIYTHKGYNDSFLKKDVGMVPLCMSNGELVDTLFYCKD
                     KKGTITFDKLNIEFTGCGWLASNFKSILFLLRNIINGRGYDLLVFHLSIRNIIPILIF
                     KSIFKGKLICKMDLNTESAIKYATCHLQSQTIKYKLMKMMVGLTDIFYIETRRNYDII
                     KKGIFGLNISEKLKIMPNGVDENLVKVVSQNGGITPRKEKILTIISRFNCEAKAPYRI
                     FDVIEIMSELNISEWTLNIIGKFPESFITDLRKKAVCHNVNIVCEGYNLELKDVYKHL
                     YKSKVFLCLSIEESYCISLVESAVFNNCIITTNVGVSADLSQKYDRIKILDTYTKEKL
                     KFYIREVIMSEQTEYCDISLKMLELYSWKKIINKTVSD"
     gene            7383..8507
                     /gene="wzy"
     CDS             7383..8507
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AFW04684.1"
                     /translation="MVIYLVLLIFIFSFSIVMMLNPSKRTANKFLGIYVLLLSLFAGL
                     RFHTGWDWEAYDYFFNLLNQANIYDFFSYNIFNYEPGFVLLSYISILLNIPPFLLFAI
                     ITVSLIVSSAHKYLGKFVPYIFCLIYLYYGYFHNFSIVRQGIAAALFAYSIRFLIVRS
                     YKFYFVIIFASLFHISAAMLLAIPLLLVIANRVPFFLLLLLSICMVLLPLSDMLGLKS
                     LMSKIPALNIYLNNSTLSYKVGFSLKYLELLIVFYCYYERKFFLPLINNFGIRQFWIF
                     KGLIIIELMIYSIFNDYSIIYERLSVYFEFSHAIAIAMIVSTFKYKRIQFFLMLILLF
                     FVFARYYQLVYSPVRVPGEMSHLERFENYCSIFNERECQR"
     gene            8495..8896
                     /gene="wejR"
     CDS             8495..8896
                     /gene="wejR"
                     /codon_start=1
                     /transl_table=11
                     /product="WejR"
                     /protein_id="AFW04685.1"
                     /translation="MPKVKMKRIIIDLDNTITIHNGDTYSNKPVNEDVVNKMRFYKEQ
                     GYTITIFTARNMKTFSGNLGKINIHTLPIIIEWLNKNDVPFDEVIVGKPWCGTEGFYV
                     DDRAIRPSEFINLSEKEIKDILGMEERNDHN"
     gene            8883..10505
                     /gene="wejS"
     CDS             8883..10505
                     /gene="wejS"
                     /codon_start=1
                     /transl_table=11
                     /product="WejS"
                     /protein_id="AFW04686.1"
                     /translation="MIIINSAAYVNDDLRAEFGLLPPCFLPLGNKRLYRYQVESLKKN
                     FPNEEIYISLPEEYVIGEFDKIFLEENAIKIIKSPYYLSQGESLSLILKELSIESNER
                     LIINYGDTLFNTFRNDSLNYFYVSKNIGYYNRAPVEINNQKFSIGQNSPAVDNGELVI
                     SGFFCFNDISMLSQCLHNAGCNFLSAIECYYSKVTTQIVMTDDWYDFGHLNSFFTSRT
                     SITTEREFNSLRIDNDCVRKKSSKKQKMLGEANWFINLPSELSIYIPRIFNVKEYDTY
                     AEYTIEYLYNLPLSDMAVFCELPASCWINVFNSCQRFLDISREYSDKSRVLNASDKEE
                     YNKLYLHKTMHRLSEFEKTTSLDLNKSITFNGVKYPSIKDIAYITSEFIKPVCEDDII
                     ITHGDFCFSNILYDFRSQRIKLIDPRGINFYNELSIWGDIRYDLAKLNHSVIGRYDLI
                     IAEHFSLAFDYGKNTINFKLFDDNFKNITDAYLKVFDSFKKLKYSSLEIDCITIHLFL
                     SMLPLHSDSKIRQDAFIANVYRLYSNLELEVL"
     gene            10502..11233
                     /gene="wejT"
     CDS             10502..11233
                     /gene="wejT"
                     /codon_start=1
                     /transl_table=11
                     /product="WejT"
                     /protein_id="AFW04687.1"
                     /translation="MTTIVIPMAGQSSRFYNAGYTVPKYKLRIDNKSVFYYALKGFNS
                     FKEHFFLIIGIKNILDENFVIKEMLKLGFDNYEIVLLDHPTNGQAETVVKGIEACGNK
                     INDIMIFNIDTFRKDINFPVEFDIGECYGYLETFIGTGMNWSNILPKDHGSHEVRMTA
                     EKQGISEYCCTGLYYFKDFSLLSESYYSWLKNNCENNEIYIAPLYNYLIKRGYRICYS
                     VINKNDVIFCGVPDEYKLIKDGFYW"
     gene            11233..12660
                     /gene="wzx"
     CDS             11233..12660
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AFW04688.1"
                     /translation="MTVNKPSTSLGILLTFFYIPAQILFALFFNYSLARSITTGMLND
                     WYVFFSLTSLFSLLELSYPTLAISFFNGKNGRSKGAFSFFIKKSLGVVIPLQIVFTVY
                     YSQMINSSFLIFGVGLILRSIANIINSYLYANKKIIIDKTYKFIYAIIMPVCFIFAHY
                     ILNVQMNITDLTTVWCISSLICLLYSSFFLVFSFKLSGQKNCCGNTFNLPIKNNIKLF
                     FTVLPAIFIYTLSINYIKYFGGPSEESGTILYGVFLQVFNIYNVIVVLVASYFIPMIS
                     KAYHDGDSISSIIFKILDVSITISVSAASFVALFGIEGVTLMLKDKVSNVSYWYIAAV
                     IMIFYIETCQVVLTSIGTGIGIYNYYKQSICSAAFVFALSYIFIPKYGVEGLMFSILF
                     SQLVTCFIFNPIIVLKVAKLSTMRYVARVVMHLGIMITLIFLAVLVKDYNLWTKVIIL
                     TSLLLFFFIFFFVKIKLLLNDYFET"
BASE COUNT     3926 a   2070 c   2638 g   4073 t
ORIGIN
        1 atctagaggt cccccaaatc gatatgtatg cagtgcactg gtagctgatg agccaggggc
       61 ggtagcgtgg ttttaagact gtatgtttac cgataaactc aatgggttat aaatgaaaaa
      121 aatacttttt atatcgatga atttaggtaa atgtgattat ggtggggctt tagtttcaaa
      181 tggaaacctc tttgctttga aagcattaaa taaatataat gtttatgcag tttcaatatc
      241 aaaaaattat agtgataata tatcgaagca tatcgaattt tctattttag ggagtaaaaa
      301 taaagtttca actgctttgt cgaatttggt tggttatgcg gggagaatga attttagagc
      361 aatgaaagaa gtcatttctc ttattgagaa tgttaaacct gatattatat atcttgactc
      421 aagtcttctt ggaaagattg cgaaaatttg caaaaaaaaa tataaagata tttttataat
      481 tacttttttt cataacgtag agattgattt tgagtttgct cgtgttagag ctggtcggat
      541 tcagttttta ccttctttaa ttgccacatc atttgctgaa gcagaagcag taaaaaatag
      601 cgataagatt ataatgttac atcaaaaaga ttctttacgc ttaaaagaaa aatatggccg
      661 tgaagctgat tattttgttc cagtatgcat aaaaaacagc gtagataaaa aaaacgcaaa
      721 attaactttt acaaagaaag aaaaagatgt tattagagtt ggatttattg gaactgcttt
      781 ctttgcgaat gtagatgcag ttaaaataat agccaatgag attgctccca aagtacttaa
      841 tattgcccat ttttatattt gtggcaaggg gtttgaaaaa tataaaacat tagagtctag
      901 taatatatca gtatctgggt atattgaatc attagataat ttttataatg acattgatat
      961 tatgattttt ccaatttatt ccggtgctgg gatgaaagta aaaattgcag agtccttaat
     1021 gtataataaa tcaattatcg caactccatt cgcgcttatt ggatatgaaa aaataataga
     1081 tggtgttaac gttgttcaat gtgagtcttc tgagtcattt atttttcaat tgaaaaatac
     1141 ttattgtcga catgattcta tttatagtcg ggacgcgtat cttaagtatt tttctgaaga
     1201 gtcatgtcac ttttattttg aaaaaatatt taacgatata gagttataga gttgaacaac
     1261 acaaaataaa actaactggt atccacgatg aaaattttac aggtgtcaaa attttatccg
     1321 cctatttttg gaggaattga acaagtagca ctagatatca ctatgggtat ggctgaaaaa
     1381 aatattccta ttgacgttct aagtgttaat aacggtccaa aaaccactgt tgaaaataat
     1441 ataatgcgtg cagcattgtt ttttactttt ctttctactc cattttctgt ttcttatgta
     1501 ttgatgtggc gaaagattcg caacaattat gatatcattc atgtacattt gccaaatcct
     1561 gttgccgttc tggcattgtt attatttcct cctcgtgcgc caataatcgt gcattggcac
     1621 agtgatatag taaaacaaaa aatagccttg aagtttttta aacctttcca gaaattgttc
     1681 ttaaaaaaag caaaaaagat aattgtaaca tctgaaatat atggtcgttc ctccccacaa
     1741 ttaaatggtt ttagagacaa aatagtttgt gttcctatcg gtattcaatc caataggtta
     1801 cctgacaatg agctgttatt gtcttcatta aaaaacaaat acaaaaataa aaaaattgtt
     1861 ttttctcttg gtaggttagt gtattataaa ggatttgaaa gtctaattaa agcagctgct
     1921 tatctatctg atgatgttat gatattaatt ggaggggagg gggaattata tgaggaatta
     1981 tatagaagca tagtaaataa taagttagag gataaagttg tgttgcttgg agcaatacaa
     2041 catcaagatc tggctgcata ttataaatta tgcgatttat tttgccttcc atctattcat
     2101 gaatctgagg catttggggt cgtacagttg gaggctatga gctatgggaa gccagttgta
     2161 tcaactaata taaaaaaaag tggtgttcca tgggtgaata agaatggagt ttcaggactt
     2221 gttgttaacc ctaatgatcc aagagaatta gcttctgcta tttctgctgt gttagaaaga
     2281 gcttgtgatt tttccatagg cgcatttgat aggtataaag agctttttac gcgagataaa
     2341 atgatcgtaa atttacttga tatatatata aaccttaatg agagtaaata gaattatatg
     2401 attcttccta ttatacttgc tggtggttct ggtagccgtt tatggccgct ttctcgcacg
     2461 ctctacccaa aacagtttct gtgcctgaaa ggcgatctca ccatgctgca aaccaccatt
     2521 tgccgtctga acggcgtgga gtgcgaaagc ccggtggtta tctgcaacga acagcaccgc
     2581 tttatcgtcg ccgaacagct ccgccagctc aataagctga cggagaacat tattcttgag
     2641 cccgccgggc gcaataccgc gccggcgatt gcgctggcgg cgctggcggc ggcgcgccag
     2701 catacggact gcgatccgct gatgctggta ctggcggcgg atcatgcgat cgccaatgaa
     2761 ggggccttcc gcgacgcggt gcgcagcgcc atgccctatg ccgacgcggg caaactggtg
     2821 accttcggta tcgtgccgga tctgccggaa accggctatg gctatatccg gcgcggtgat
     2881 gccgtgccgg gcgcgacgga tgcggtggct tttgaggtgg cgcagttcgt tgagaagccg
     2941 gggctggaaa ccgcccaggc ctacgtcgcc agcggcgatt actactggaa cagcggcatg
     3001 tttctgttcc gcgccggacg ctatctggaa gagctgaaaa agttccgccc cgatattctg
     3061 gccgcctgtg aacaggcgat gcgcggcgtc gatccggatc ttgacttcat tcgcgtggat
     3121 gaagaggcct tcctcgcctg tccgcaagag tccattgact atgcggtgat ggagcggacg
     3181 gcggacgcgg tggtgatgcc gatggacgcg ggctggagcg atgtcggctc gtggtcctcg
     3241 ctgtgggaga tcagcgccca caccccggag ggaaacgtcc atcacggcga cgtcatcagc
     3301 cataaaacgg aaaacagcta cgtttacgcc gaatccggcc tggtgaccac cgtcggcgtg
     3361 aaggatctgg tggtggtgca gaccaaagac gcggtgctga ttgccgatcg ccacgcggtg
     3421 caggacgtaa aaaaggtggt ggagaagatc aaggccgacg gacgccatga gcaccacatg
     3481 caccgcgagg tttaccgtcc gtggggcaaa tacgactcca tcgacgcggg cgagcgctat
     3541 caggtgaagc gtattaccgt caagccgggg gaaggactgt cggtgcagat gcaccatcac
     3601 cgcgccgagc actgggtggt ggtggcgggg accgccagag tcaccatcaa cggcgaggtt
     3661 aagctgctcg gtgaaaacga gtccatctat attccgctgg gggcgaccca ctgcctggaa
     3721 aatccgggaa aaataccgct cgatttaatt gaagtgcgtt ctggttcgta tctcgaagag
     3781 gacgacgtgg tgcggttcga ggaccgttac gggcgggtct gacgccttaa attatgcccg
     3841 gtaagcgcaa cgcgccgtcc ggcaatgaac aacaataacg attttggcca tttacggcca
     3901 gggctaactg ttgcctgaag aagggtaaga acatgacaaa attaacctgt ttcaaggcct
     3961 acgacattcg cggcaggctg ggcgaagagc tcaatgaaga tatcgcgtgg cggattggcc
     4021 gcgcctacgg tgaatattta aaaccgcaaa ccatcgtgct gggcggcgac gtgcggctga
     4081 ccagtgagtc cctgaagctg gcgctggcga aagggttaca ggatgcgggc gtcgacgtgc
     4141 tggatatcgg gatgtccggg accgaagaga tttacttcgc cacgttccac cttggcgtgg
     4201 acggcggtat tgaagtgacc gccagccata acccgatgga ctacaacggc atgaagctgg
     4261 tgcgcgaggg cgcgcgcccg ataagcggtg acaccggtct gcgcgacgtt cagcgcctgg
     4321 cggaagctaa cgacttcccg ccggtcaacg acgccgcgcg cggcagctac agacaaatca
     4381 ccctgcgcga cgcctacatc gaccacctgc tcggctacat cagtgttaaa aatctcaccc
     4441 cgctgaagct ggtggtgaat tccggtaacg gcgcggcggg gccggtcatc gacgccatcg
     4501 aagcccgcct gaaggcgctg ggcgcgccag tggagttcat caaaatccac aacaccccgg
     4561 acggcacctt cccgaacggc attcccaacc cgttgctgcc ggagtgtcgc gacgacaccc
     4621 gcaacgccgt tattgaacac ggggcggaca tgggcatcgc ctttgacggc gacttcgacc
     4681 gctgtttcct gtttgatgag aaagggcagt tcattgaggg gtactacatc gtcggcctgc
     4741 tggcggaagc gtttctggaa aaacacccgg gggcgaagat tattcacgac ccgcgcctga
     4801 cctggaacac cgaggcggtg gtgacggcgg cgggcgggac gccggtgatg tcgaaaaccg
     4861 ggcacgcctt tatcaaggag cggatgcgtc ttgaggatgc ggtgtacggc ggcgagatga
     4921 gcgcgcatca ctatttccgc gattttgctt actgcgacag cgggatgatc ccgtggctgc
     4981 tggtggcgga gctggtgtgc ctgaaaggac agtcgctggg cgggctggtg gcggaccgga
     5041 tggcgacgtt cccggcgagc ggggaaatca acagcaggct ggcggagccg gcggcggcga
     5101 ttgcccgggt ggagcggcat tttgccggcg aggcgctggc ggtggaccgt actgacggca
     5161 tcagcatgtc gttcgccgac tggcgcttca acctgcgctc gtcgaacacc gaaccggtgg
     5221 tgcgcctgaa tgtggaaaca aaaaaaaata atgagctctt aaataagcaa acagcctttg
     5281 tcattagctt attgaggaat aaaaacaatg atacgaagta atgatataac gtttgttgta
     5341 caggggccta ttagagatgc gacaaaagaa acgcttaaga gcatcagact taactttaag
     5401 gagtcaataa taatattatc tacatgggag ggaagcgatg tacaagggct tgacttcgat
     5461 acagtaattt acaataaaga tcccggttca ttagatataa gaaaaaataa aatagtagta
     5521 agtcaagaaa atacaaatag gcagatagtc tcaacacatc acgggttgat taaagtaaaa
     5581 actcaatatg ctgttaaatt aagaacagac atgcctattc ttaacacaaa tataataaaa
     5641 tattataaga aagctcagtg ttatgaatct gacattaact tcacattatt agaagaaaga
     5701 gttctggttt cgtctataaa tactatagac ccaaatagct atattaaatt cccataccat
     5761 atatcagatt ggatttattt tggtaaaact agtgatttgt taaaaatttg gaatggggaa
     5821 ttagtaccta acgacgagta tttcaccgag cagaatatta aagaagaagt atgctgtgaa
     5881 agaggatttg attttgggcg gttcacagca gaacaacttg tactatattc ctttttaaga
     5941 aaaaacagaa ttaatgatta taatttttat tgcgatgtta atgaatacaa aatagaaaaa
     6001 gctataaaat atacgctttc aaatttttac tgtgttagtc caaaaaaact gggggtttgt
     6061 tttaataaat atgaagatct cattaatatt aaaatgagtt ataatagttt acgacattat
     6121 tttggttttt acttagtaac tattaatgaa agtgtttgga gaaactacta cagcaaatat
     6181 tacagtctaa aaacctctat tacagaaaaa ttagaaatta atataagaag actggcttta
     6241 cattttatga gaaaattaaa acatgaaaaa tagattgtta tatatttata cgcataaagg
     6301 ttataacgat tcttttttaa agaaagatgt gggcatggta cctttgtgta tgtccaatgg
     6361 tgaattggtt gatacgcttt tttattgcaa agataaaaaa gggacaataa cttttgataa
     6421 gttgaatatt gaatttacag gttgcggatg gctggcaagc aattttaaat ctatattatt
     6481 cttattacga aatattatta atggacgagg gtatgattta ttggtgttcc atttaagcat
     6541 cagaaatatt ataccgatac ttatttttaa aagtatattt aaaggaaaac ttatatgcaa
     6601 aatggattta aatactgaaa gtgctataaa atatgctaca tgccatctcc agagtcaaac
     6661 aataaaatat aagctaatga aaatgatggt cggcctgact gatatttttt atatagagac
     6721 aaggaggaat tatgatataa taaaaaaagg aatatttggt cttaacatta gtgagaagtt
     6781 gaaaataatg cctaatgggg tggatgaaaa tttagttaaa gtagtttctc agaatggggg
     6841 tattactcca cgtaaagaaa agatattaac gatcatatct cgttttaact gcgaagctaa
     6901 ggctccgtat agaatatttg atgtgattga aattatgtct gagctaaaca tttctgaatg
     6961 gacattaaat attattggta aattcccgga atcatttatt actgatttaa ggaaaaaagc
     7021 ggtctgccat aacgtgaata tcgtttgtga aggctataac ttagagctta aggacgttta
     7081 taaacatcta tataaaagta aagtttttct ttgtctttct attgaggaat cctattgtat
     7141 ttcgttagtg gagtcggctg tatttaacaa ttgtattata actactaatg ttggtgtgtc
     7201 tgcagatctt tcgcagaaat atgacagaat aaaaattcta gatacgtata ctaaggagaa
     7261 gttaaaattt tatattcgag aggtaatcat gagcgaacag actgaatact gtgatatttc
     7321 gcttaagatg ttagagctat attcatggaa aaaaattatt aataaaactg taagcgactg
     7381 acatggtaat ctatctggtt cttcttattt ttattttttc tttctctata gtgatgatgt
     7441 taaatccttc gaaaaggact gctaacaaat ttttaggcat atatgtattg ttgctatcac
     7501 tatttgcagg tttaagattt catactggtt gggattggga agcgtatgat tattttttta
     7561 atctattaaa tcaagctaac atttatgatt tttttagtta caatatattt aactatgaac
     7621 ccggttttgt attactttca tatatatcaa tattattaaa tattccacct tttctgcttt
     7681 ttgctataat aactgtatct ctcatcgtat cctctgctca taaatactta ggtaaatttg
     7741 tcccctatat attttgtttg atttatctgt attatggtta ttttcataac ttttcaatag
     7801 tacgacaagg aatagcagct gctttatttg cttactctat tcgttttctt attgttagga
     7861 gttacaaatt ttattttgtc ataatttttg cttcgttatt ccatatatca gcagccatgt
     7921 tactagctat accgttactc cttgtgatag ctaatcgggt tccgtttttt ttactactgc
     7981 tattatctat atgtatggtt cttttgcctt taagtgatat gctgggctta aaatcattaa
     8041 tgtctaaaat accggcatta aatatttacc taaataatag cacgttaagt tacaaagtcg
     8101 gattttcatt aaaataccta gagttgctaa ttgtatttta ttgttattat gaaagaaagt
     8161 tttttttgcc acttataaat aattttggaa taagacagtt ttggatcttt aaagggctca
     8221 ttataattga gctgatgatt tattctattt ttaatgatta tagtatcatt tatgaaagat
     8281 tgagtgtata ttttgaattt tcacacgcta tcgcaatagc aatgatcgtt tcaactttta
     8341 aatataaaag aatacaattt tttctaatgc ttatattgct tttttttgta tttgcaagat
     8401 actatcaatt agtttattcc cctgtccgag tgccaggcga aatgtcacat cttgaacgat
     8461 tcgaaaatta ttgttctatt tttaacgaaa gagaatgcca aaggtaaaaa tgaaaagaat
     8521 cattattgat ttagataata ctattacaat ccacaatgga gatacatata gcaataaacc
     8581 tgtaaatgaa gatgttgtta ataaaatgag gttttataaa gaacagggtt atactataac
     8641 tatatttaca gcaagaaata tgaagacatt ttcaggtaat cttgggaaaa ttaatatcca
     8701 cacacttcct attataattg aatggctgaa taaaaatgat gttcctttcg atgaggtgat
     8761 tgttggaaaa ccttggtgtg ggaccgaagg tttttatgtt gatgatagag caatcaggcc
     8821 atctgaattt atcaatttat cggaaaaaga aataaaggat atacttggta tggaggaaag
     8881 aaatgatcat aattaattct gcagcttatg tcaatgatga tttgagagcc gaatttggtc
     8941 tattgccacc ttgttttttg ccattaggaa ataagcgact atataggtac caagttgagt
     9001 ctctaaaaaa gaattttccc aatgaagaaa tatatatttc tcttcctgaa gagtatgtta
     9061 ttggggagtt tgataaaatt tttttagaag aaaatgctat taagatcatt aaaagtccat
     9121 attatctttc gcaaggggaa agtctttcac taattttaaa agagttatcc atagagagta
     9181 atgagcgact tattattaat tatggtgata ccctattcaa tacattccga aatgatagct
     9241 tgaattattt ttatgtatct aagaacatcg gatattataa tcgagctcct gttgaaatta
     9301 acaatcagaa atttagtata ggacagaata gtccagctgt agataatggt gagttggtta
     9361 tatcaggttt tttctgtttc aacgacattt ctatgcttag tcaatgcttg cataatgctg
     9421 gttgcaattt tttatcagcg attgagtgct attattccaa ggttacaact caaatagtga
     9481 tgacggatga ttggtatgat tttggccatt tgaatagttt ctttacttcg agaactagta
     9541 tcacgactga acgcgagttt aatagtctcc gtattgataa tgattgcgtc cgaaagaaaa
     9601 gcagtaaaaa acagaaaatg ctaggtgaag ctaattggtt tattaacttg ccaagtgagt
     9661 tgtctatata catacctagg atctttaatg ttaaagaata tgatacttat gctgaatata
     9721 ccattgagta tctctataat ttaccattat ctgatatggc tgttttttgt gaattaccgg
     9781 cctcttgctg gataaatgta tttaactcat gtcaaagatt tttggatatt tctagggaat
     9841 attcagataa aagtagggtt ttaaatgcta gtgataaaga agaatataat aaactgtatt
     9901 tacataaaac gatgcataga ttatctgaat ttgaaaagac aacatcgtta gatctaaata
     9961 aatcgattac ttttaatggt gtcaaatatc cttcaattaa ggatatcgca tatatcactt
    10021 ctgaatttat taagccagtg tgtgaagatg atattataat tacgcatggg gacttttgtt
    10081 ttagtaatat tctttacgat ttcagaagtc agcgaattaa attaattgat ccccgtggta
    10141 ttaacttcta taatgaatta agcatatggg gcgatatccg atatgattta gcaaagctaa
    10201 atcattcagt aattggacgt tatgatctaa taattgcaga acacttctca ctcgcatttg
    10261 attatgggaa aaacaccata aattttaaat tatttgatga caatttcaaa aatatcacgg
    10321 atgcttattt aaaagttttt gattcattta aaaaactgaa atattcatct ttggaaatag
    10381 attgtataac aattcatctc tttttatcaa tgctaccact tcattctgat tcgaagatta
    10441 gacaagacgc tttcatcgct aacgtgtatc gactgtatag taatttagaa ttggaggttt
    10501 tatgactacg atcgttattc caatggcagg tcagtcatca cgattctaca atgccggata
    10561 tacagttccc aaatacaaat taagaataga taataaatct gttttttatt atgcacttaa
    10621 aggatttaat tcttttaaag agcatttttt cttgattatt ggtattaaaa atattttaga
    10681 cgaaaacttt gtaattaagg agatgttaaa gcttggcttt gataactacg aaattgtttt
    10741 acttgatcat ccaacaaatg gacaagctga aactgtcgtc aaaggtattg aagcttgcgg
    10801 taataaaatt aacgatatta tgatttttaa tatagatact tttaggaaag acataaactt
    10861 tcccgtagag tttgacattg gcgaatgtta cggttattta gagactttta ttggtacggg
    10921 tatgaactgg agtaatattt tgccaaaaga tcatggttct cacgaagtta gaatgacggc
    10981 agaaaaacag ggtatatctg agtactgctg tacaggacta tattatttta aggactttag
    11041 cttactaagt gaatcatatt acagttggtt gaagaataat tgtgaaaata atgaaatata
    11101 tatagcgccc ttgtacaatt atttgattaa aagaggatat agaatatgtt attcagtgat
    11161 aaataaaaat gatgttattt tttgtggtgt tccggatgaa tataaattaa taaaagatgg
    11221 attttattgg taatgacagt aaataaaccc tctacaagtc taggaatatt attgactttt
    11281 ttttatatac cagcgcaaat cctgtttgcg ttgttcttta attattccct agccaggagt
    11341 attacaacgg gaatgttaaa tgattggtac gttttttttt cacttacatc tctattttct
    11401 ttacttgaac tttcatatcc aacattagct ataagttttt ttaatgggaa aaatgggcgt
    11461 tcgaaaggcg ccttttcttt ctttataaaa aaatcactag gagtagtgat accacttcaa
    11521 atagttttta cagtttacta tagtcagatg attaattcga gtttccttat ttttggagtc
    11581 gggttaattt tacgaagcat tgccaacatt ataaactctt atctctatgc caataaaaaa
    11641 ataataattg ataaaactta taagtttatc tacgctataa ttatgccagt gtgttttatt
    11701 tttgctcact atattcttaa tgtgcagatg aacattactg atctaacaac cgtatggtgc
    11761 ataagctcgt taatatgtct tctatattct tcttttttct tggtatttag ttttaaacta
    11821 tctggccaaa aaaattgctg cggcaacact ttcaatttac caattaaaaa taatataaaa
    11881 ctttttttta cagttttacc agcaatattt atatacacat tatcaattaa ttatattaag
    11941 tattttggag gtccttcaga agaaagtgga actatcttat atggtgtctt tttacaagta
    12001 tttaatattt acaatgtgat tgttgtatta gtagcaagtt attttatacc catgatttcg
    12061 aaggcttatc atgatggcga tagtatcagt tctataattt ttaaaatatt agatgtaagc
    12121 ataactatct ctgtctcggc cgcttcattt gtagctttat ttggtattga aggggtgacc
    12181 ctgatgctaa aagacaaagt aagtaacgtg tcttattggt atattgctgc ggtgattatg
    12241 attttttata tagaaacttg tcaggtagtt ttaacatcaa taggtactgg cataggtatt
    12301 tataattatt ataaacaaag tatatgttca gcggctttcg tttttgcctt atcctatata
    12361 tttattccaa aatatggtgt tgaaggtttg atgtttagta tattattttc acaacttgta
    12421 acttgtttta tttttaatcc aattattgta ttgaaagtag ctaaattgtc aacaatgcgc
    12481 tatgtagcaa gagttgtaat gcatcttggg ataatgataa ctttaatttt ccttgctgtg
    12541 ttggtgaagg attataatct ttggaccaaa gtaataatac ttacatcttt attacttttt
    12601 ttctttattt tcttctttgt gaagataaag cttttattga atgattattt tgagacataa
    12661 cagcgatact gatattatta tatgtcgcag tttaactgac atctaag
//
