LOCUS       EU294174               17769 bp    DNA     linear   BCT 26-AUG-2008
DEFINITION  Shigella dysenteriae O antigen gene cluster, complete sequence.
ACCESSION   EU294174
VERSION     EU294174.1
KEYWORDS    .
SOURCE      Shigella dysenteriae
  ORGANISM  Shigella dysenteriae
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Shigella.
REFERENCE   1  (bases 1 to 17769)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Wang,Q., Reeves,P.R. and Wang,L.
  TITLE     Structure and genetics of Shigella O antigens
  JOURNAL   FEMS Microbiol. Rev. 32 (4), 627-653 (2008)
   PUBMED   18422615
REFERENCE   2  (bases 1 to 17769)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Wang,Q., Reeves,P.R. and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-NOV-2007) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23# HongDa Street, Tianjin
            300457, P. R. China
FEATURES             Location/Qualifiers
     source          1..17769
                     /organism="Shigella dysenteriae"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:622"
                     /note="type: 5"
     gene            1137..2222
                     /gene="rmlB"
     CDS             1137..2222
                     /gene="rmlB"
                     /note="dTDP-D-glucose 4,6-dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlB"
                     /protein_id="ACA24859.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGDLESLA
                     DVSDSERYVFEHADVCDAAVMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPHPDEVNNKEQLPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYIVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGDYQSWIEQNYEGRQ"
     misc_feature    1137..16267
                     /note="O antigen gene cluster"
     gene            2222..3121
                     /gene="rmlD"
     CDS             2222..3121
                     /gene="rmlD"
                     /note="dTDP-4-dehydrorhamnose reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlD"
                     /protein_id="ACA24860.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGNGDMPWLETDATAPRNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            3179..4054
                     /gene="rmlA"
     CDS             3179..4054
                     /gene="rmlA"
                     /note="glucose-1-phosphate thymidylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlA"
                     /protein_id="ACA24861.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDVAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEKVKVLAEPL
                     KKNAYGQYLLKMIKG"
     gene            4062..4604
                     /gene="rmlC"
     CDS             4062..4604
                     /gene="rmlC"
                     /note="dTDP-6-deoxy-D-glucose-3,5 epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlC"
                     /protein_id="ACA24862.1"
                     /translation="MNVIKTEIPDVLIFEPKIFGDERGFFFESFNQKVFEEAVGRKVE
                     FVQDNHSKSCKGVLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVN
                     LSAENKRQLWIPEGFAHGFITLSNIAEFLYKTTDFYSPKHEVCIRYDDESIGIQWPKA
                     TDKMLISSKDKKGLDFTSLM"
     gene            4728..5915
                     /gene="wzx"
     CDS             4728..5915
                     /gene="wzx"
                     /note="O antigen flippase"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="ACA24863.1"
                     /translation="MKINACLSFGTTLCKMITGLLFLAILSHSINNAEYSIIVTSIFF
                     AQLLSVFVDGGINNEVLSLTNKSLDNDIDGYQKLSMNGAVRLVVHLFFSFVLSTYFMF
                     ADGWSAGGVFFWGYISGVLTSILETYSIKLKTEYKYIEDFILNIFCSLFVILSSFFIY
                     IFPQCLMLYLVFFRLIPLAIYRKPLQVFKMIREIDYKLIRDNYIARKHYPIDSIATNI
                     NLQLDSFFLLLLFGRDMYAYYQPLNRLYNSCIGLSAAVVSFAIPYAHLLTSRIKKIYF
                     LVFLFSSSAIIISLSYYFFSRDVVMVFFGEKFSMERQYIFLFSLLIFMRYLCASFGSY
                     LMTNGEQKKRALINLTITILCIPFILISETYSGILVVIIGGQILISYFYVLMIKRGVG
                     HDK"
     gene            5905..6513
                     /gene="wfeZ"
     CDS             5905..6513
                     /gene="wfeZ"
                     /note="acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="WfeZ"
                     /protein_id="ACA24864.1"
                     /translation="MINKTHIIFLKFICRVLIKKNQFESCILRRLYIKLYDIDIGMYS
                     YGCFDPKRVPPKTKIGRYCSFAPTAYIFGRNHGVEFVSLHPYLYNSELGLVKQDTIAI
                     TSRVIEDDVWFGHNSVISPAVKFIGRGAFIATGAVVTSDVPRYAIVAGVPAKIIKYRF
                     EPRVINIIEKSKWWLRTKSELQKMIKLDSGFIFTPGYFDETN"
     gene            6500..7708
                     /gene="wffA"
     CDS             6500..7708
                     /gene="wffA"
                     /note="pyruvyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="WffA"
                     /protein_id="ACA24865.1"
                     /translation="MKPIKICLAWHNINSTNYGVSALAVAQVALLVESASRSKVAIEL
                     ETFGTPFVNELSIRKEVEQRFAVKLTHRDFSLKKFIVDFAKLDFSGLRLFDKYDIVMD
                     IGEGDSFTDIYGIKRFITFSITKYLALRVKKKLILSPQTIGPFNSRISYIIARYLISK
                     CDSVFSRDYKSTKFIHDMGLNCEEVSDVAFTLPYDTLPKIDNSIGINISGLLWNGGYT
                     GDNQFGLTVDYKLFVKEIIELFRVRGKEVHLIGHVIADHLPVEDDYRVCNQIKEMFSL
                     DNGVIVAPKFTSPIQAKTYMSQLTFFTGSRMHATIGALSAGVVTVPIAYSRKFSGVFG
                     SLDYRFTLDAYTLDTKSLVTKLFEYYDNNFEEMQSAMINARIKANQRNEKYVGYLQEL
                     LSNEKNSTSH"
     gene            7683..8864
                     /gene="wffB"
     CDS             7683..8864
                     /gene="wffB"
                     /note="hydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="WffB"
                     /protein_id="ACA24866.1"
                     /translation="MKKIAQVIESGMCVGCGFCTENPNGMDINKEGYYRPISFIDDSL
                     SQLVCPGKSISHNNSMAPYNLLWGPVVSCESGNAVDPDIRHKGSSGGVLTAIAVYLVD
                     SGLVDAIIQVGVSVDNPIRNVTYIMKSQEDILKCAGSRYSPSSPLSVIRSLLGNGTRY
                     AVIGKPCDIAAMRTLVNSRQEFQEQFPYLLSFMCAGVPSEEGTRNILERWHIKHEHLI
                     SFRYRGDGWPGLTKAITDDGEEFTMTYNESWGGVLNRYLQPRCKLCADGIGEAADIVC
                     ADAWYSTTNGYPSFIEKEGRSLTIARTLKGRQLLDLALNKNVISLTPFNISDLEKIQP
                     YQANRKQTANVRRWAVMLLGGSVPNFKGYSLNKLMFRAPIKITLKAFFGTLIRKMKGR
                     I"
     gene            8977..9798
                     /gene="wffC"
     CDS             8977..9798
                     /gene="wffC"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACA24867.1"
                     /translation="MNKVNVIVALYYPNYYQRVREEIISFLQGFDYFIVFVDNNRTVK
                     PNIENNKNVTWIIGSNIGGEFSAWDEGYDLLVNVKNPSDDEIIVFINDTFCHHHFFTC
                     FDRYLYRKAISTCEDNNIYGDVNSIGEFFSVYDRHFSSWVSSYFFLGRKKNIDKLLPL
                     NKQSGMDAEYMRYLSNALVSKRVDVPIFSDKLNQHLTNWLFPVNSKGWYGARNVSQQL
                     ILFKLNAIINEKLLTYNIIEHDLLLTNIYHGKIRTLYNSMRNKLYFFCKNNKLIG"
     gene            9803..11134
                     /gene="wzy"
     CDS             9803..11134
                     /gene="wzy"
                     /note="O antigen polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="ACA24868.1"
                     /translation="MYANKAMPKRHTRERVFLPLLLSMIFICMIINDLPLQQYLGTLG
                     ASPMWGGALFIFMLIVIRSRFVLNLDSTSKYFLYFYLLTFTISLLQCFYYAISRGSVE
                     NEYGGLIFGKLVFASTYYIVYFFTIYTAIFLARRITSSALKFCIINASVLLLLLLILE
                     FFSPNSLSLFHKSMDGYGFGFRQRLLSPEPSMAAFTLNIFLLISIVLVNSKIAKLFMG
                     GALVVGNLFIGSKASLILILMSGVIVFYLNMNLTQKIKSLLILIPVSIAVFYVFLNTI
                     LPALIVDVDKFTSVSTRLITALAALLSLIYYPLGEGYGTYSSYLLGPLDLAVQLAEEL
                     LPFTLNVSEVNKMLMTGESLAAKSGILFSVIQSGVVSLIFFYVIYRNAFRKLCAARLS
                     NYNKIMMRLVLWYSLLSIMFAVNIEVVYAFLLPFIIIDHYAINYMRSYDYE"
     gene            11127..12251
                     /gene="wffD"
     CDS             11127..12251
                     /gene="wffD"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACA24869.1"
                     /translation="MNKILYISLSLDEKNYGGSIVSRNNLKALRALEDSEVKEVAIVK
                     KLKGIYEYELQTNVSKVKIAIDNLKGYAGRSNRDCLLKIKNIIKVFEPKFVYLDSSLL
                     GGIAELSKEISTDIKVITFFHNVEIDFELERLKSGGILYLPSLLPSYLAEKKAIKYSD
                     IIISLHKNDSARLKCIYGRSSDFCVPVCIEDDLSNEVILHKNNSTDSIFRVGFIGTAF
                     FANIKAAEFISKKLSPRFLNNKQIEFIIAGNGFDKYSKLLNRKSVKTLGYINSIEDFY
                     NEVDVIISPVLTGAGMKVKIAEAIKYNKKVIASSFSLIGYETMLNSQNIFSCITLDDY
                     VIAIKKLSTHPMTHSDTREYYLKFFSSQACINYFKYILNS"
     gene            12333..13442
                     /gene="wffE"
     CDS             12333..13442
                     /gene="wffE"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACA24870.1"
                     /translation="MKVLQVSKFYPPVHGGIEQVAFDISEGMFEEHIQAVDILCVDPL
                     GPRIDDRNYKYRVFRQKTFIVLFSTPISISFINKWRKIKDNYDIIHVHLPNPLAVLAI
                     YLFPPKGKIVLHWHSDIVKQKKLFRLFLPLQRWILDRCTYIIVTSPVYGQSSPSLQQY
                     QNKLICIPIGVDTSVMPVDLQEEKLIKSKYKDKKIIFSLGRLVYYKGMDILIDSAKYL
                     PDDYIILIGGGGALLKKLRRQIYDNNLSHKVVVLGSIDYKCLASYYKCCDVFCLPSIH
                     ESEAFGVVQLEAMSFSKPLVSTNIPRSGVPWVNENGTSGIVVEPRSAIALAEGIVKTI
                     ANSEKFSKGAKDRFDMLFTKRLMVNNVYKLYLSIK"
     gene            13451..14878
                     /gene="manC"
     CDS             13451..14878
                     /gene="manC"
                     /note="mannose-1-phosphate guanyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="ManC"
                     /protein_id="ACA24871.1"
                     /translation="MSLLPVIIAGGTGSRLWPLSRVKHPKQFLHLGDDGTMLQTTLNR
                     LQGLKCDNPIVICNEQHRFIVAEQLRQLNKLTQNIILEPVGRNTAPAVTLAALNAIRN
                     KSKQSKLILVLAADHIIKDEDAFCRSVLSAIPYANKGKLITFGIVPNSPETGYGYIKR
                     GHLCSGNNANLAFEVAEFVEKPNIDTAQEFLSSGNYYWNSGMFLFRADRYLDELKKYR
                     PDILEACKKSMIELNGDLDFIRINKDAFCACPDESIDYAVMEKTNDAVVIPMDAGWSD
                     VGSWSSLWEMSNKTIEENVIVGDVVTYDSDSSYLRSGSGLLATVGVKDLVVVQTKDAV
                     LVANRNSVQNVKKIVERLKSENRSEVFTHLEVYRPWGKYESIDNGERYEVKRISVKPG
                     EGISLQMHHHRSEHWIIVSGTAKVTICDETRILSENESIYIPVGAKHCLENPGKIMLE
                     LIEVRSGSYLGEDDVIRFADRYGRT"
     gene            14879..16267
                     /gene="manB"
     CDS             14879..16267
                     /gene="manB"
                     /note="phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="ManB"
                     /protein_id="ACA24872.1"
                     /translation="MHNKIILDKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKP
                     KTIVLGGDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVT
                     ASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDA
                     YVDHLFGYINVKNLTPLKPVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGN
                     FPNGIPNPLLPECHDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLL
                     AEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGE
                     MSAHHYFRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAHP
                     VEAINRVEQHFSREALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLME
                     EKTKLILELLNK"
BASE COUNT     5293 a   3045 c   3877 g   5554 t
ORIGIN
        1 attgtggctg cagggatcaa agaaatcctc ctggtaactc acgcgtccaa gaacgcggtc
       61 gaaaaccact tcgacacctc ttatgaatta gaatctctcc ttgagcagcg cgtgaagcgt
      121 caactgcttg cggaagtgca gtccatctgt ccaccgggcg tgaccattat gaacgtgcgt
      181 cagggcgaac ctttaggttt gggccgctcc attttatgtg cacgacctgc cattggtgac
      241 aacccatttg tcgtggtgct gccagacgtt gtgatcgatg acgccagcgc cgacccgctg
      301 cgctacaacc ttgctgccat gattgcgcgc ttcaacgaaa cgggccgcag ccaggtgctg
      361 gcaaaacgta tgccgggtga cctctctgaa tactctgtca tccagaccaa agagccgctg
      421 gatcgtgagg gtaaagtcag ccgcattgtt gaatttattg aaaaaccaga tcagccgcag
      481 acgctggact cagacatcat ggccgttggt cgctatgtgc tttctgcaga tatttggccg
      541 gaacttgaac gcactcagcc tggtgcatgg gggcgtattc agctgactga tgctattgcc
      601 gaactggcta aaaaacagtc tgttgatgca atgctgatga caggcgacag ctacgactgc
      661 ggtaaaaaaa tgggctatat acaggcgttt gtgaagtatg gactgcgtaa cctaaaagaa
      721 ggggcgaagt tccggaaagg gattgagaag ctgttaagcg aataatgaaa atctgaccgg
      781 atgtaacggt tgataagaaa attataacgg cagtgaagat tcgtggcgaa agtaatttgt
      841 tgcgaatctt cctgccgttg ttttatataa acaatcagaa taacaatgag ttagcaatag
      901 gattttagtc aaagttttcc aggattttcc ttgtttccag agtggattgg taagacaatt
      961 agcgtttgaa tttttcgggt ttagcgcgag taggtaatgc tcgtcacatc gtcggcatgc
     1021 atgcagtgct ctggtagctg taagccaagg gcggtagcgt gcattaatac ctctattaat
     1081 caaactgaga gccgcttatt tcacagcatg ctctgaagta atatggaata aattaagtga
     1141 aaatacttgt tactggtggc gcaggattta ttggttctgc tgtagttcgt cacattataa
     1201 ataatacgca agatagtgtt gttaatgtcg ataaattaac gtacgccgga gacttggaat
     1261 cacttgctga tgtttctgat tccgaacgct atgtttttga acatgcggat gtttgcgatg
     1321 cagctgtaat ggcacggatt tttgctcagc atcagccgga tgcagtgatg cacctggctg
     1381 ctgaaagcca tgttgaccgt tcaattacag gtcctgcggc atttattgaa accaatattg
     1441 ttggtacata tgtccttttg gaagccgctc gcaattactg gtctgctctt gatagcgaca
     1501 agaaaaatag cttccgtttt catcatattt ctactgacga agtctatggt gatttgcctc
     1561 atcctgacga agtaaataat aaagaacaat tacccctctt tactgagacg acagcttacg
     1621 cgccaagcag tccttattcc gcatcaaaag catccagcga tcatttagtc cgtgcgtgga
     1681 aacgtaccta tggtttaccg accattgtga ctaactgttc gaataactac ggtccttatc
     1741 actttccgga aaaattgatt ccactagtaa ttcttaatgc tctggaaggt aaggcattac
     1801 ctatttatgg caaaggggat caaattcgtg actggctgta tgttgaagat catgcgcgtg
     1861 cgttatatat cgtcgtaacc gaaggtaaag cgggtgaaac ttataacatt ggtggacaca
     1921 acgaaaagaa aaacatcgat gtagtgctca ctatttgtga tttgttggat gagattgtac
     1981 cgaaagagaa atcttaccgc gagcaaatta cttatgttgc cgatcgcccg ggacacgatc
     2041 gccgttatgc gattgatgca gagaagatta gccgcgaatt gggctggaaa ccgcaggaaa
     2101 cgtttgagag cgggattcgt aaaacggtgg aatggtacct gtccaataca aaatgggttg
     2161 ataatgtgaa aagtggtgac tatcaatcgt ggattgaaca gaactatgag ggccgccagt
     2221 aatgaatatc ctcctttttg gcaaaacagg gcaggtaggt tgggaactac agcgtgctct
     2281 ggcacctctg ggtaatttga ttgctcttga tgttcactcc actgattact gtggtgattt
     2341 tagtaatcct gaaggtgtag ctgaaaccgt aagaagcatt cggcctgata ttattgtcaa
     2401 cgcagccgct cacaccgcag tagacaaagc agaatcagaa ccggagtttg cacaattact
     2461 taacgcaaca agtgtcgaag cgattgcgaa agcagcaaat gaagttggag cttgggttat
     2521 ccattactcg actgattacg tcttccctgg aaatggcgac atgccatggc tggagacgga
     2581 tgcaaccgca ccgcgaaatg tttacggtga aaccaagtta gctggagaaa aagcattaca
     2641 agagcattgt gcgaagcacc taattttccg tacaagctgg gtctatgcag gtaaaggaaa
     2701 taacttcgcc aaaacgatgt tgcgtctggc aaaagagcgt gaagaattag ccgttattaa
     2761 tgatcagttt ggtgcgccaa caggtgctga actgctggct gattgtacgg cacatgcaat
     2821 tcgtgtggca ctgaataaac cagaagtcgc aggcttgtat catctggtag ccagtggtac
     2881 cacaacctgg cacgattatg ctgcgctggt ttttgaagag gcgcgcaaag caggcattcc
     2941 ccttgcactc aacaagctca atgcagtacc aacaacagcc tatcctacac cagcccgtcg
     3001 cccccataac tctcgcctta atacagaaaa atttcagcag aactttgcgc ttgtcttgcc
     3061 tgactggcag gttggtgtga aacgaatgct caacgaatta tttacgacta cagcaattta
     3121 atagtttttg catcttgttc gtgatggtgg agcaagatga attaaaagga atgatgaaat
     3181 gaaaacgcgt aaaggtatta ttttagcggg tggttctggt actcgtcttt atcctgtgac
     3241 tatggctgtc agtaaacagc tattacctat ttatgataag ccgatgatct attacccgct
     3301 ttctacactg atgttagcgg gtattcgcga tattctgatt atcagtacgc cgcaggatac
     3361 tcctcgtttt caacaactgc tgggtgacgg gagccagtgg gggctaaatc ttcagtataa
     3421 agtgcaaccg agtccagatg gtcttgcgca ggcatttatc atcggtgaag agtttatcgg
     3481 tggtgatgat tgtgctttgg ttcttggtga taatatcttc tacggtcatg atctgccgaa
     3541 gttaatggat gtcgctgtta acaaagaaag tggtgcaacg gtatttgcct atcacgttaa
     3601 tgatcctgaa cgctacggtg tcgttgagtt tgataaaaat ggtacggcga tcagcctgga
     3661 agaaaaaccg ctacaaccaa aaagtaatta tgcggtaacc gggctttatt tctatgataa
     3721 cgacgttgtg gaaatggcga aaaaccttaa gccttctgcc cgcggtgaac tggaaattac
     3781 cgatattaac cgtatttata tggaacaggg gcgtttatct gttgccatga tgggccgtgg
     3841 ttatgcatgg ctggacacgg ggacacatca aagcctgatt gaggcaagca acttcattgc
     3901 aacaattgaa gaacgtcagg ggctgaaagt ttcctgcccg gaagaaattg cttaccgtaa
     3961 agggtttatt gatgctgaga aggtgaaagt attagctgaa ccgctgaaaa aaaatgctta
     4021 tggtcagtat ctgctgaaaa tgattaaagg ttagtaataa aatgaacgtt attaaaacag
     4081 aaattccaga cgtattaatt ttcgaaccga aaatttttgg tgacgagcgc ggtttctttt
     4141 tcgagagctt taaccagaag gtttttgagg aagctgtagg ccgcaaagtt gaatttgttc
     4201 aggataatca ttcgaagtct tgcaaaggtg ttttacgcgg actgcattat cagttagaac
     4261 cttatgctca aggaaaactg gtacgctgtg ttgttggtga agtttttgat gttgcggttg
     4321 atattcgtaa atcgtcacct acctttggca aatgggtagg ggtgaattta tctgctgaga
     4381 ataagcgcca gttatggatc ccggaggggt ttgcgcatgg gttcataacg ttgtcaaata
     4441 tagccgaatt tctttataaa acaacagatt tttattctcc aaaacatgag gtttgcattc
     4501 ggtatgatga tgagagcatt ggtatacaat ggcctaaagc aactgacaag atgttgatat
     4561 cttcaaaaga taaaaaaggt ttggatttta cttctttaat gtgagttatt atatgctaat
     4621 tttatatcta ttaatttctt cgcatgcatc tgaaaattta ttatagctgg ctcaatggac
     4681 attacattga tttctattaa tggatggttt tactcaaagt aaatataatg aaaataaatg
     4741 cttgtttgtc atttggaaca acattatgta agatgatcac tggtcttctc tttttggcaa
     4801 tcttatcgca ttcaataaat aatgctgaat atagcattat tgtaacatcg attttttttg
     4861 cccagttact ctccgttttt gttgatggtg ggatcaataa tgaagttctc tcactaacta
     4921 ataagtcatt agataacgat attgatggat atcagaaact atcaatgaat ggagcagtta
     4981 ggctagttgt tcatttgttt ttttcttttg tgttatcaac ttattttatg tttgctgatg
     5041 gatggagtgc tgggggggtg tttttttggg gatacatttc tggggtacta acctcaatat
     5101 tagaaacata ctctataaaa ttaaaaacag aatataaata tattgaggat tttattttaa
     5161 atattttttg cagtctgttt gttattttat catctttttt tatttacata tttcctcaat
     5221 gtcttatgtt atatcttgtt ttttttagat taatcccttt ggctatatat agaaaaccat
     5281 tgcaagtatt taaaatgata agagaaatag attataaatt aataagggat aattatatcg
     5341 cacggaaaca ttaccctatc gattcgattg cgacaaacat taatttacaa ttagactcgt
     5401 tttttctatt gttattattc ggtagagata tgtatgcata ttatcaacca ttgaatcggt
     5461 tatataattc atgtataggg ttgtcggcag cagttgtatc atttgctatt ccatatgcac
     5521 atttactgac aagtagaata aagaagatat actttttagt tttcttgttt tcatcatcag
     5581 caattataat ttcattatca tattattttt tttctagaga tgtcgtgatg gtattctttg
     5641 gtgaaaaatt ttctatggaa agacaatata tatttctatt tagtttattg atttttatgc
     5701 gatatttatg cgcctcattt ggttcatatt taatgacaaa tggagagcaa aaaaaaagag
     5761 cactcataaa tcttactatt actattttat gcattccatt tatattaatt tctgaaacgt
     5821 attctggaat attggtggtg ataattggag ggcaaatatt aatatcatac ttttacgtac
     5881 taatgatcaa aagaggagtt ggtcatgata aataaaaccc atatcatctt tctgaagttt
     5941 atatgtcgtg ttctcattaa aaaaaatcaa tttgaaagtt gtatattgag acgattatat
     6001 ataaaactat atgatattga tattggtatg tatagctatg gttgttttga ccctaaaaga
     6061 gtgccaccta aaacaaaaat aggaagatat tgttcgtttg caccaacagc atatatattt
     6121 ggacgaaatc atggggttga atttgtctcg ttgcatccat atttatataa ttcagagttg
     6181 ggtttagtaa aacaagacac catagcaata acttcacgag tgatagaaga cgacgtttgg
     6241 tttgggcata atagtgtaat ttcacctgcg gtaaaattta tagggagagg ggcttttatc
     6301 gctactggag cagttgtcac tagcgacgtt cctagatatg cgattgttgc aggagttccg
     6361 gcaaagatca tcaaatatag atttgaaccg agagtgataa atattattga aaagagtaaa
     6421 tggtggttaa gaacgaaatc tgaattacaa aaaatgatta aattagatag tgggtttata
     6481 tttacaccgg ggtattttga tgaaaccaat taaaatttgc ttagcatggc acaatattaa
     6541 ttcgactaac tatggcgtta gtgctcttgc agttgcacaa gttgctcttt tagttgagtc
     6601 tgcgagtcgt tcaaaagttg ctattgaatt ggagactttt ggtacaccgt ttgttaatga
     6661 gttatcaatt agaaaggaag tagagcaaag atttgcagtt aaattaacac atagagattt
     6721 ctcattaaaa aagtttattg ttgattttgc aaaacttgat ttttctggac ttaggttatt
     6781 tgacaaatac gatattgtaa tggacattgg tgagggtgac agttttacgg atatatatgg
     6841 aattaagaga tttattacat tctcaattac aaagtattta gcgttaagag ttaaaaagaa
     6901 actcattctt tcacctcaaa caatcggacc ttttaatagc agaatatcat atataatagc
     6961 gcgttatttg atttcgaaat gtgattcagt tttttctcgt gactataaat ctacgaaatt
     7021 catacatgac atgggattga attgtgaaga agtatcagat gtagcattta ctctaccata
     7081 tgatactttg cccaagatag ataacagtat tggtatcaac atttcaggtt tgttatggaa
     7141 tggtggttac acaggcgata atcagtttgg attgacagtt gattataagt tattcgtcaa
     7201 agagattatt gaattattta gagttagagg gaaggaagtt catttgattg gacatgtcat
     7261 tgcagaccat ctacctgtgg aagatgacta tcgtgtttgc aatcaaatta aagaaatgtt
     7321 ttcattagat aatggagtaa tagtagcacc taaatttaca tcacctatcc aagctaaaac
     7381 ttatatgagt cagttaacat tttttactgg atcacgtatg catgcaacca ttggggcact
     7441 atctgcagga gttgtaacag tacctatagc gtatagtcga aaattctctg gagtatttgg
     7501 tagtttggat tatcgtttta ctttggatgc ttatacatta gataccaaaa gtttagtgac
     7561 aaaattattt gagtattatg ataataattt tgaagaaatg caatctgcaa tgattaatgc
     7621 aagaattaaa gcaaatcaaa gaaacgaaaa atatgttggt tatcttcagg aattattaag
     7681 caatgaaaaa aatagcacaa gtcattgaat ctggaatgtg tgtgggttgt ggattttgca
     7741 ctgaaaaccc caatggtatg gatattaata aagaaggata ttatagacct atttctttca
     7801 ttgatgattc attatcacag ctagtatgcc ctggtaaatc tatttcccat aataacagta
     7861 tggctcctta taacctttta tgggggccgg tagtgagttg tgagagtgga aatgcagttg
     7921 acccagatat acgtcataag gggtcttctg gtggggtttt aaccgccatt gcagtttatc
     7981 ttgttgattc tggattggtt gatgcaataa tacaggttgg tgtttcagtt gataatccaa
     8041 tacgcaatgt aacatatata atgaagagtc aggaagatat attaaaatgt gctggctctc
     8101 gctattcacc ttcatcacca cttagtgtca ttcgttcatt attaggtaat ggtacacggt
     8161 acgctgttat tggtaaaccc tgtgatattg cggctatgcg cacattggtt aatagtcggc
     8221 aagaatttca agagcagttt ccatacctac tttcatttat gtgtgctgga gtgccaagtg
     8281 aagaaggtac aagaaatatt cttgagcgat ggcacataaa acatgaacat ttaatctcgt
     8341 ttcgttatcg aggagacgga tggccaggat tgacaaaagc tattactgat gatggtgaag
     8401 agtttactat gacttataat gaatcatggg gcggtgtact taatcgctac ttacagcctc
     8461 gttgcaaact atgtgctgac ggtattggtg aagctgctga tattgtatgt gcagacgctt
     8521 ggtattctac tactaacggc tatcctagtt ttatagagaa ggagggacgt agtttaacaa
     8581 ttgctcgtac acttaaaggc cgtcaattgt tggatcttgc tttaaataaa aatgtaatat
     8641 cacttacacc ttttaatatt tctgatcttg agaaaattca accataccaa gctaatcgta
     8701 aacagacggc aaatgttcgt cgctgggctg ttatgcttct ggggggaagt gtgccgaatt
     8761 ttaaaggtta tagtcttaat aaattaatgt ttagagcccc aataaaaatt actttaaagg
     8821 cattttttgg tacattgata agaaaaatga agggacgtat ttgaaaacta attatatatt
     8881 cttcggtttt tttgtgagca ttgtacaatc atcactgatt ataaataacc gcaataggaa
     8941 ttattaaacg tgttgaataa caatatggta ttttaaatga ataaagtaaa cgttattgtt
     9001 gcactttatt atccaaatta ctatcagagg gttagggaag agattatttc ttttctgcag
     9061 gggtttgatt attttatagt gtttgtggac aataatagaa cggtcaaacc aaatatagag
     9121 aataataaaa atgtaacgtg gataataggg agtaatattg gtggtgaatt ttctgcttgg
     9181 gatgaaggtt atgacctcct ggttaatgtg aaaaatccgt cagatgatga aattatagtt
     9241 tttattaatg atacattttg tcatcaccat ttttttacat gtttcgatag gtatttatat
     9301 aggaaagcaa tatctacatg tgaagataat aacatttatg gtgatgttaa cagtataggc
     9361 gaatttttta gtgtttatga tcggcatttt tcatcttggg tatcttctta tttttttcta
     9421 ggtagaaaaa aaaacattga taaactttta cctcttaata aacaaagtgg tatggacgca
     9481 gaatatatga gatatcttag taatgcattg gtatctaagc gcgttgatgt tcctatcttt
     9541 tcggataaat tgaatcagca tctcacgaat tggttatttc cagttaatag caagggatgg
     9601 tatggcgcaa gaaacgtatc acagcaactt attctgttta aactgaatgc aataattaat
     9661 gaaaaattgc tcacttataa tataattgaa catgatcttt tattaacaaa tatttatcat
     9721 ggaaaaataa gaacgcttta caattctatg cgtaacaagc tatatttttt ttgcaaaaat
     9781 aataagttga tagggtgata taatgtatgc aaataaagca atgcccaaaa gacatacgag
     9841 agaaagagtg tttttaccac tattactttc gatgattttc atttgcatga taataaatga
     9901 tttgccacta caacaatatc ttggaacttt aggtgcaagt cctatgtggg ggggggcatt
     9961 atttattttt atgttgattg ttattcgtag ccgctttgtt ttaaatcttg attctaccag
    10021 taaatatttt ctctattttt acctattaac atttactata tcgcttttac aatgtttcta
    10081 ttatgccatc tctagaggtt ctgtagaaaa cgagtatggt ggattgattt ttggtaagct
    10141 tgtatttgct tcgacgtatt atatcgttta tttttttact atatacactg ccattttttt
    10201 ggctagaaga ataacatcct ctgctcttaa attttgtatc ataaatgctt ctgttttgtt
    10261 gcttcttctt cttattttgg agtttttttc gccaaactca ttgagtttat ttcataaaag
    10321 tatggatggc tatggctttg gatttagaca aaggttattg tcccctgaac catcaatggc
    10381 tgcgtttact ttaaatattt tcttgttgat aagcatagta ctggttaact caaagatcgc
    10441 taaactattt atgggaggtg cgcttgtagt aggcaaccta tttattggct ctaaagcttc
    10501 gctcatatta attttgatga gtggtgttat tgtgttttat cttaatatga acttaaccca
    10561 aaaaataaaa tcgttactta tattaattcc tgtatcaatt gcagtttttt atgtgttttt
    10621 aaatacgatt cttccagcac tgattgtaga tgtagataaa ttcacaagtg ttagcactcg
    10681 tttaataaca gcccttgcgg ctctgctgag tttaatatac tatccattgg gtgagggcta
    10741 tggtacctat agttcttatc ttttgggacc tcttgattta gctgttcaat tagcagaaga
    10801 actattgcct tttacattaa atgtaagcga ggtcaataaa atgctaatga ctggtgagtc
    10861 gttagcagca aagtcaggta ttcttttttc tgttatccag agtggagtcg tttccctcat
    10921 atttttttac gtgatttatc gaaatgcgtt tagaaaactc tgtgctgcca ggctatctaa
    10981 ttataacaag ataatgatgc ggttggttct atggtattca ttgttatcaa tcatgtttgc
    11041 tgttaatatt gaagttgtct atgctttttt attgccgttt attataattg atcattatgc
    11101 tataaattat atgcgatctt atgattatga ataaaatttt atatatctcg ctctctcttg
    11161 atgagaaaaa ctatggtggc agcatcgtgt ctagaaataa tttaaaagca ttgagggcac
    11221 ttgaagatag tgaggtgaag gaagttgcaa tagttaagaa attaaaaggg atatatgaat
    11281 atgaactaca aactaatgtg tcaaaagtaa aaatagccat agataacctg aagggatatg
    11341 ctggacggtc aaatcgcgat tgtttattga aaattaaaaa tattataaaa gtctttgagc
    11401 ccaaattcgt ttatcttgac tccagtttgc ttgggggaat agctgaacta tctaaagaga
    11461 tatctacaga cataaaagtt attacatttt ttcataatgt cgagattgat tttgaattag
    11521 aaagattgaa gtcaggggga atattgtact tgccttctct tttgccatct tatttagcgg
    11581 aaaaaaaagc tataaaatat agtgatataa taatttcact tcataaaaat gatagtgcta
    11641 ggcttaagtg catatatgga cgttcgtctg atttttgtgt cccagtttgt atagaagatg
    11701 acttgagtaa cgaggtaata ttacataaaa ataatagtac agatagtata tttagagttg
    11761 gttttattgg aactgcattt ttcgcgaata ttaaagctgc agagttcatt tcgaaaaaat
    11821 tatcacctag gtttttgaat aataaacaaa tagaatttat tattgcgggt aatggtttcg
    11881 ataagtactc aaaattactt aatcgtaaaa gcgtaaaaac tctgggctat attaattcaa
    11941 ttgaagactt ttataatgaa gttgatgtta taatatctcc tgtcctgacg ggagcaggca
    12001 tgaaagtgaa aatagcggaa gcgattaaat ataataagaa ggtaattgcc tcgtcatttt
    12061 cattaattgg atatgagact atgttaaata gtcaaaatat tttttcttgc attactctag
    12121 atgattatgt gatagcaatt aaaaagttga gcacacatcc tatgactcac tctgatactc
    12181 gtgaatatta tttgaaattt ttctcaagtc aagcatgtat taactatttt aaatatattt
    12241 tgaactccta atagttaaaa tgctacttct atgtgtgttt attgtgttga gttttttgtt
    12301 ttactgcttt tatgtagtag aggatgatgc tgatgaaggt attgcaagtt agcaagtttt
    12361 acccacctgt acatggagga attgagcaag tcgcgtttga tatcagtgaa ggcatgtttg
    12421 aagaacatat acaggctgtt gatatcttat gtgtagatcc attgggacct cgtattgatg
    12481 ataggaatta taaatatcga gtttttcgac aaaagacttt tattgttcta ttttccactc
    12541 cgatttcaat atcatttata aataaatggc gaaaaataaa agacaattat gatattatcc
    12601 acgtacattt acctaaccct ttagctgttc tcgctatata tctttttcct ccaaaaggta
    12661 aaattgtatt acattggcat agtgatattg ttaagcaaaa aaaattattc agattatttt
    12721 tacctttaca aagatggatt ttggataggt gcacttatat aattgtgact agtccagtgt
    12781 atggtcaatc atctccatcg ctgcaacaat atcaaaataa attaatttgt attcctatag
    12841 gtgtagatac cagtgttatg cctgttgacc tacaagaaga aaaattaatt aaaagtaagt
    12901 ataaagataa aaaaataata ttttcattag ggcgattggt ttattataaa ggtatggata
    12961 ttttaattga ttcagcgaaa tatttacctg atgattacat catattaatt gggggggggg
    13021 gcgcattatt aaaaaaatta aggaggcaga tttatgataa taacttatca cacaaggttg
    13081 ttgttttggg aagtatagat tataaatgct tagcttcata ttataaatgc tgtgatgtat
    13141 tttgtctccc atctatacat gagtctgaag cgtttggtgt ggtacaatta gaagcaatga
    13201 gtttttcaaa gccattagtt tctacgaata tcccccgaag tggtgttcca tgggttaacg
    13261 aaaatggaac atcaggaatt gttgttgagc caaggagtgc tatagctctt gctgaaggga
    13321 ttgttaaaac tattgctaat agtgaaaaat tcagtaaagg agcaaaagat agatttgata
    13381 tgctctttac taagagatta atggttaata atgtatacaa attatattta agtataaagt
    13441 gagtcaaaat atgtctttac ttcctgttat cattgctggt ggtaccggta gtcgtttgtg
    13501 gcctttatca cgagttaagc atccaaagca atttctccat ttaggggatg atggaacaat
    13561 gttacagacg acattaaatc gtcttcaagg gttaaagtgt gataacccaa ttgtaatttg
    13621 caatgagcag catagattta tagttgctga gcaacttcga caattaaata aactcactca
    13681 gaatattatt cttgagcccg tcggccggaa tactgcacca gctgtaactc tcgctgcact
    13741 gaatgcaata cgtaataagt caaaacaatc aaaattaatt ttggttcttg cagctgatca
    13801 tattataaaa gacgaagatg cattttgtag aagtgtgctg agtgctattc catatgcaaa
    13861 caaaggaaaa ttaatcacat ttggtatagt gcctaatagt cccgaaacag gctatggata
    13921 tataaaaaga ggtcatttat gtagtggcaa taatgctaat ttagcttttg aagtggctga
    13981 gttcgttgaa aaacctaaca tagatacagc tcaagagttt ctttcatctg gtaactatta
    14041 ttggaatagt ggtatgtttt tatttcgagc tgataggtat ttagatgaat taaaaaaata
    14101 tagaccagac atacttgagg cctgtaaaaa atcaatgatt gaacttaatg gagatcttga
    14161 ttttattcgt atcaataaag atgctttttg cgcttgccca gatgagtcaa ttgattatgc
    14221 cgttatggag aaaacgaatg atgcggttgt tatcccaatg gatgctggct ggagtgatgt
    14281 ggggtcatgg tcatctttat gggaaatgag taataaaacc attgaagaaa atgtaatagt
    14341 tggtgatgta gtaacttatg attctgacag cagctacctc cgttcaggtt cagggctgct
    14401 tgctacagtt ggggtaaaag atcttgttgt tgttcaaaca aaagatgctg tgttagtagc
    14461 taataggaat tcagttcaga atgtaaaaaa aattgtcgaa aggcttaaat cagaaaatcg
    14521 tagtgaagtt tttacgcatc ttgaagttta tcgtccttgg ggtaaatatg agtctatcga
    14581 taatggtgaa cgctatgaag ttaaacgaat ttccgtaaaa cctggagagg ggatttcatt
    14641 gcaaatgcat caccatcgtt ctgaacattg gataatagtt tcgggtactg caaaagtaac
    14701 aatttgtgat gaaacaagaa ttctcagtga aaatgaatct atttatatac ctgtcggggc
    14761 gaaacattgt ttagagaatc cgggaaaaat tatgttggag cttatagaag ttcgctccgg
    14821 ctcctatcta ggagaagatg atgtcatccg ttttgccgac agatatggaa gaacataaat
    14881 gcacaataag atcatcctag ataaattaac ttgctttaaa gcctacgata ttcgcggaaa
    14941 actaggcgag gaactgaatg aagatatcgc ctggcgcatt ggtcgcgcct atggcgaatt
    15001 tctcaaaccg aaaaccattg tgttaggcgg cgatgtccgc ctcaccagcg aaaccttaaa
    15061 actggcgctg gcgaaaggtt tacaggatgc gggcgtcgat gtgctggata tcggcatgtc
    15121 cggcaccgaa gagatttatt tcgccacgtt ccatctcggc gtggatggcg gcattgaagt
    15181 taccgccagc cataatccga tggattataa cggcatgaag ctggtgcgcg aaggggctcg
    15241 cccgatcagc ggcgataccg gactgcgcga cgtccagcgt ctggcagaag ccaacgactt
    15301 tcctcccgta gatgaaacca aacgcggtcg ctatcagcaa atcaatctgc gtgacgctta
    15361 cgttgatcac ctgttcggtt atatcaacgt caaaaacctc acgccgctca agccggtgat
    15421 taactccggg aacggcgcgg cgggtccggt ggtggacgcc attgaagccc gctttaaagc
    15481 cctcggcgca cctgtggaat taatcaaagt acacaacacg ccggacggca atttccccaa
    15541 cggtattcct aacccgctgc tgccggaatg ccacgacgac acccgcaatg cagtcatcaa
    15601 acacggcgcg gatatgggca ttgcctttga tggcgatttt gaccgctgtt tcctgtttga
    15661 tgaaaaaggg cagtttatcg agggctacta cattgtcggt cttctggcag aagcgttcct
    15721 cgaaaaaaat cccggcgcga agatcatcca cgatccacgt ctctcctgga acaccgttga
    15781 tgtggtgacc gccgcgggcg gcactccggt gatgtcgaaa accggacacg cctttattaa
    15841 agaacgtatg cgcaaggaag acgccatcta cggtggcgaa atgagcgccc accactattt
    15901 ccgtgatttc gcttactgcg acagcggcat gatcccgtgg ctgctggtcg ccgaactggt
    15961 gtgtctgaaa ggaaaaacgc tgggcgaact ggtgcgcgac cggatggcgg cgtttccggc
    16021 aagcggtgag atcaacagca aactggcgca ccccgttgag gcgattaatc gcgtcgaaca
    16081 gcattttagc cgtgaggcgc tggcggtgga tcgcaccgat ggcatcagca tgacctttgc
    16141 cgactggcgc tttaacctgc gctcctccaa caccgaaccg gtggtgcggt tgaatgtgga
    16201 atcgcgcggt gatgtaccgc tgatggaaga aaagacaaaa cttatccttg agttactgaa
    16261 caagtaattc agtaatttca tataaatggg ttttaaaaaa cggaaaagat gagatatccg
    16321 gtgtggtata gccaaggtaa tgctattcag tatctctatg agtgagttaa catctatacc
    16381 acatttaagc cgcacacttg gcggtaacca cccctgacag gagtaaacaa tgtcaaagca
    16441 acagatcggc gtcgtcggta tggcagtgat gggacgcaac ctcgcgctca acatcgaaag
    16501 ccgtggttat accgtctcta ttttcaaccg ttcccgtgat aagacggaag aaattattgc
    16561 cgaaaatcca ggcaagaaac tggttcctta ctatacggtg aaagaattcg ttgaatctct
    16621 tgaaacgcct cgtcgcatcc tgttaatggt gaaagcaggt gcaggcacgg atgctgctat
    16681 tgattccctt aagccatacc tcgataaagg tgacatcatc attgatggtg gtaatacctt
    16741 cttccaggac accattcgtc gtaaccgtga gctttctgcc gaaggtttta acttcatcgg
    16801 taccggtgtt tccggcggtg aagagggggc gctgaaaggg ccttccatca tgcctggtgg
    16861 ccagaaagaa gcctatgaac tggttgcgcc gatcctgacc aaaatcgccg ccgttgctga
    16921 agatggcgaa ccgtgcgtta cctatatcgg tgccgatggc gcgggtcact atgtgaagat
    16981 ggttcacaac ggtattgaat acggtgatat gcaactgatt gctgaagcct attctctcct
    17041 gaaaggcggc ctgaatctct ctaacgaaga actggcacag acctttaccg agtggaataa
    17101 cggtgaactg agcagctacc tgatcgacat caccaaagat atcttcacca aaaaagatga
    17161 agacggtaac tatctggttg atgtgatcct ggatgaagcg gctaacaaag gtaccggtaa
    17221 atggaccagc cagagcgcgc tggatctcgg cgaaccgctg tcgttgatta ctgagtcagt
    17281 gtttgcacgt tatatctcgt ctctgaaaga tcagcgcgtg gccgcgtcta aagttctctc
    17341 tggtccgcaa gcacagccag ctggcgataa agctgagttc atcgagaaag ttcgtcgtgc
    17401 gctgtatctg ggcaaaatcg tttcttacgc tcagggcttc tctcagctgc gtgaggcgtc
    17461 tgaagagtac aactgggatc tgaactacgg cgaaatcgcg aagattttcc gtgctggctg
    17521 cattatccgt gcgcagttcc tgcagaaaat caccgatgct tatgccgaaa atccgcagat
    17581 cgctaacctg ctgctggctc cgtacttcaa gcaaattgcc gatgactacc agcaggcgct
    17641 gcgtgatgtc gttgcttatg cagtacagaa cggtatcccg gttccgacct tcgctgctgc
    17701 ggttgcctat tatgacagct accgtgccgc tgttctgcct gcgaacctga tccgggctca
    17761 gcgcgacta
//
