LOCUS       EU296416               11423 bp    DNA     linear   BCT 26-AUG-2008
DEFINITION  Shigella dysenteriae type 9 O-antigen gene cluster, complete
            sequence.
ACCESSION   EU296416
VERSION     EU296416.1
KEYWORDS    .
SOURCE      Shigella dysenteriae
  ORGANISM  Shigella dysenteriae
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Shigella.
REFERENCE   1  (bases 1 to 11423)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Wang,Q., Reeves,P.R. and Wang,L.
  TITLE     Structure and genetics of Shigella O antigens
  JOURNAL   FEMS Microbiol. Rev. 32 (4), 627-653 (2008)
   PUBMED   18422615
REFERENCE   2  (bases 1 to 11423)
  AUTHORS   Liu,B., Knirel,Y.A., Feng,L., Perepelov,A.V., Senchenkova,S.N.,
            Wang,Q., Reeves,P.R. and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2007) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23# HongDa Street, Tianjin
            300457, P. R. China
FEATURES             Location/Qualifiers
     source          1..11423
                     /organism="Shigella dysenteriae"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:622"
                     /note="type: 9"
     gene            1402..2571
                     /gene="wffO"
     CDS             1402..2571
                     /gene="wffO"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACD37109.1"
                     /translation="MKSVNTKIKIAHLQLMPLLSGVQRVSLQEIENLPPEYFEIDLIC
                     KEGGPLVDALNKKVRKFFIPTLCRNISPVEDLKSLISLYKIFKRERYDIVHTHSSKTG
                     ILGRIAARMAKVPCVVHTVHGFAFESTKKQAIKNLYKWLEMIGAKCSTKIICLHEEDK
                     NICLNILKIKADKIVVIPNGVDINKFTPATNKGKIKEEILSLRESNFVFTMVGRLWPQ
                     KNPLYFVEVAKQIIKNELIPGSIFVLVGDGELMSVIKEHYLEDELLHNRLLLLGWRND
                     ISDILKASDVFVLPSLWEGMPLAILEAQSTGLPCVVSNINGNKSLVTNKVDGYLVELN
                     DINSFINALVNISEKNVYARMSNNCRAKIVSNYNITQRIEKIKIMYYQLLNVNMN"
     misc_feature    1402..9991
                     /note="O-antigen gene cluster"
     gene            4624..5376
                     /gene="wffP"
     CDS             4624..5376
                     /gene="wffP"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACD37110.1"
                     /translation="MKCFVVSLKNSGRRKDFDHRFKIFNYQFFDAITECTSNQFNSAI
                     AKSIYGRCLRKGEIGCSLSHFNIIRDFALNSKENWLLIMEDDAVPESQFIHFINEFEN
                     KHVTTNAEVILLGHSKTSRKHIFVQRLKQPLRNYKNINGISFGENKNVTLCGTVAYLI
                     NKQAANIISGNSQPYWLADDWFLFQNMGIRVYHPQIPLVYEDLSYDSSTENDIYYHHN
                     FIKEPLKNIIHIIIGQYKFWNDSRKLRKSNNK"
     gene            5373..6578
                     /gene="wzy"
     CDS             5373..6578
                     /gene="wzy"
                     /note="O-antigen polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="ACD37111.1"
                     /translation="MSHFGGGLMKSVNNFNFYLAIFIGMFDLTIFSTGNSLGQALTTV
                     LLLFSILSDINKVFLKPFFFVISYIVLALLVSLFHGETSYHYSFIIVKTGLILFNAMV
                     ISQILILYADKKQISNFVNFIFLIQTISLLLYSNELFQMMRGFFLSARSEHLYENFSD
                     SYWYRDATISNQGYSGYALGALPLVIIAVHNIMKSKFFSIRYFVAVVCCGLGVSVAML
                     NGRSVFLFIPLYMIYLMLRPKEICLTYKIIPVILIIVSAIIIVLTNFDISSNFVLAFF
                     EQKDKSYGIDSVDDLMYNHTILHFDITLFGLGKYLLSDGSAFVRSDIGYYRQMGVGGI
                     SLVLFYIFSIWLAVRYVIYRDLSLFILFIILLANFKQEAFNNAMLMYGAFLLAAYWVA
                     RDKIEITKK"
     gene            6575..7693
                     /gene="wffQ"
     CDS             6575..7693
                     /gene="wffQ"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ACD37112.1"
                     /translation="MKIILWHLGRKGAGPKYNLEMALALKKEGYDVYACISKQAENAN
                     DYKKHNINHLSLNTYTGGVSALINSLRLPWLINEFKDYLKINRITHVYCTMPHIWNFF
                     FSKRFKKLDISYLLTIHDAELHSGEENKLIDILMKKDRKNADGIVVLTKHVKEQLKNL
                     GKSIFIIPHPAFSFNNNKNSAKSIVPDQKIKLLFFGRIHHYKGLDILIDAFEKLNKKN
                     NRYSLSIYGSGNISPYQKKILELSNITVHNRWIDDVEIPSIISSHDVCVIPYRDASQS
                     GVIPTVMTCGVPLVVTPVAGLKEQVVHLQTAIFAEEVSSDSVARAIDSLVKDISLYEK
                     ISKNALLYAQEEMGWEKTAYRSVEALISITHNSKKYNQ"
     gene            7775..9055
                     /gene="wzx"
     CDS             7775..9055
                     /gene="wzx"
                     /note="O-antigen flippase"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="ACD37113.1"
                     /translation="MFQNGVNISFYSFIAKATVFLCGPLTLLLISHKLSTEEIAFYYT
                     FFNLIALQQLVELGLGFTLKQCISHAYKIENDVWLYDSKKIVKSYIQFGLYWFIGVSC
                     IIIFVIGPLGLIYYGDYEGSIKWQGAWLGTIGVLAFSIILVPIQIAIEATQNQIAIYR
                     CQVIYSLTNSLSLWVFIYNDFKLYSIPLSMLIANIFLLIALKNHYIKLYNKLAFVKEM
                     DKFWTIFSKLWPLFSRVAIVWGVGFLLWNGFNLISFKIFSPEEAGRIIFSITLARAGF
                     TIAESIICAQTTVVSNMISKGENTEAAKYYRKYQLISFAVLIIGYGFYYVVKCFFSDF
                     YLFDKLMPNSFITSVFVFFVLLLILTTKCNFIRCYKIEPFVKVSVWHGLGVPMSFLLS
                     SLYFPMYLYPCSFVLFISIIWSQLISKRILSKIG"
     gene            9059..9991
                     /gene="wffR"
     CDS             9059..9991
                     /gene="wffR"
                     /note="pyruvyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="WffR"
                     /protein_id="ACD37114.1"
                     /translation="MINNWVALMDSLKNSHSEIANLIGEARIAFIDIPMYFNVGDLLI
                     YFGTEAFIKEYNLNVIYRTGMNVDLKKLKDVDVILFQGGGNFGDLYPHHQQLREKITL
                     KFPNKKIICLPQTLHFNNEEELERSAKIFKKHSDFHLYVRDQESLTIGYQFTDNIKLI
                     PDMAHSLHPLIDINECDINRESYRILHMVRSDKEANSNNANNMLSKRSFDWANIISPS
                     MYLMGRSIIILDKLRYSNSMKFWDKIASDMVFKSINYFMSHNEVYSDRLHGIILAALL
                     GKKIRCFDNNYKKNSRYISCWLKEYPSLKNASDF"
BASE COUNT     3731 a   1756 c   2272 g   3664 t
ORIGIN
        1 attggtagct gtaagccaag ggcggtagcg tgggtatttt gaagcattta tacctcctta
       61 ttcagtgaga agggacagat tacgtaacac tgctttgttg tactaaataa ttcgcatttt
      121 atgttcaaca atcgagatat tccttattac ctaaagctgt ttttcattgt ttatacatga
      181 tcgaagactc cttacataaa taaggagaac aaaatggaac ttaaaaaatt gatggaacat
      241 attctattat acccgattcc agacaagtct ggaaagtgga acataaatta tcggatattc
      301 tactgttgac tatttgtgcc gttatttctg gtgcagaagg ctgggaaaat atagggtttt
      361 tggggaaact catctcgatt ttttgaagca atatggtgat tttgaaaatg gtattcctgt
      421 tcacggtacc attgccagag ttatatcctg tatcagtcct gcaaaatttt acgagtgcct
      481 tattaactgg atgcgtggat gccattcttc aaatgataaa gacgtcatcg caattgatgg
      541 aaaacactcc ggcattctta tgacaagagt cgccgcaagg gagtgattca tgtcattagt
      601 gcgttcttaa caatgcacat tctggttcaa gacagatgag aaatccaatg agattacagc
      661 tatccctgag cttattaaca cgttggatat taaaggaaaa attatcacaa ctgatgcgat
      721 gggttgcctg aaagatattg ctgagaagat acaaaaacag ggaggtgatt atttattcgc
      781 tgtacacgga aaccaggggg ggcttaataa agcctttcag gaaaaatttc cgctgaaaga
      841 attaaataat ccagagcatg acagttacgc aatgagtgaa aagagtcacg gcagagaaga
      901 aatccgtctt tatattgttt gcgatgtccc tgatgaactt attgatttca cgtttgaatg
      961 gaaagggctg aaaaaattct gtgtggcagt ctcctttcgg tcaataatag cagaacaaaa
     1021 gaaagagcca gaaatgacgt tcagatatta tatcagttct gctgatttaa ccgcagaaaa
     1081 gttcgccaca gcaatccgaa accactggta cgtggagaat aagctgcact ggcgtctgga
     1141 tgtggtaatg aattaagacg actgcaaaat aagaagagga aacgcagcag aattattttc
     1201 acggatgcgg tacatcgcta ttaatatttt tacgaatgat aaggtattca aggcagggtt
     1261 aagacgtaag atgcgaaaag cagccatgga cagaaactac ctagcgtcag tccttgtggg
     1321 gaacgggttt tcgtaatttt gccatgggtg ctaaggaaga aacgagaata ttattattcc
     1381 atagattgga tctgtcataa gatgaaatca gttaatacta aaattaaaat tgcacatcta
     1441 caattaatgc ccttgttaag tggtgtccag cgagtatctt tgcaggaaat tgaaaattta
     1501 cctcctgagt attttgagat tgatttaata tgtaaagagg gtgggccgtt agttgatgcg
     1561 ctaaataaaa aagttagaaa gttctttatc ccgactcttt gtagaaatat ttctccggtt
     1621 gaggatttaa aatccttgat tagcttatat aaaatattca aaagagaaag atatgatatt
     1681 gtgcatacac actcttcgaa aacaggtatt ctaggaagaa tagctgcacg tatggctaaa
     1741 gttccgtgtg ttgtgcatac agttcatggt tttgcatttg aaagtacgaa aaaacaggca
     1801 ataaaaaatc tatacaaatg gctggagatg attggtgcaa aatgctctac aaaaataata
     1861 tgtctccatg aggaagacaa aaatatatgt ttaaatatac taaaaataaa agcagataaa
     1921 attgtagtta ttccaaatgg tgttgatata aataagttca ctccagcaac gaataaaggt
     1981 aaaataaaag aagaaatatt aagcttgaga gaatcaaatt ttgtttttac tatggtagga
     2041 cgattatggc cacaaaaaaa tcccttatat tttgttgagg ttgctaaaca aattataaaa
     2101 aatgaactaa tacccggttc gatttttgta ctcgttggtg atggtgaatt gatgagtgta
     2161 ataaaagaac attatcttga agatgagttg ttacataata ggttgttatt attaggttgg
     2221 cgaaatgata tctcagatat tttgaaagct agcgatgtat tcgtactccc ttctctttgg
     2281 gaaggaatgc cattggccat actggaagcc caatcaacag gtttaccatg cgtagtatct
     2341 aacattaatg gaaataaatc attagttacg aataaagtcg atggctactt ggttgaactt
     2401 aacgatatta atagctttat caacgcacta gttaatatta gtgaaaaaaa tgtttatgcc
     2461 agaatgtcta ataattgccg tgcaaaaata gttagtaatt acaatataac acaaagaatt
     2521 gaaaaaataa aaatcatgta ttatcaacta ctaaatgtaa acatgaacta gcatgttttt
     2581 gtaatgtatg tttatttcat ataaggttgc agggaaagaa catcagaagt acactttttg
     2641 tactgaataa ttcgcatttt atgttcaata tttgagatat tccttattac ctaaagctgt
     2701 tttccattgt ttatacatga tcgaatactc cttacataaa taaggagaac aaaatggaac
     2761 ttaaaaaatt gatggaacat atttctatta tccccgattc cagacaagtc tggaaagtgg
     2821 aacataaatt atcggatatt ctactgttga ctatttgtgc tgttatttct ggtgcagaag
     2881 gctggaatga tatagagagt tttggggaaa ctcatctcga ttttttgaag caatatggtg
     2941 attttgaaaa tggtattcct tttcacgata caattgccag ggttgtatcc tgtatcagtc
     3001 ctgcaaaatt tcacgagtgc tttattaact ggatgcgtga ctgccattct tcaaatgata
     3061 aagacgtcat cgcaattgat ggaaaacact ccggcattct tatgacaaga gtcgctgcag
     3121 gggagcgatt catgtcatta gtgcgttctc aacaatgcac agtctggtca tcggacagat
     3181 caagacagat gagaaatcca atgagatcac aactatccct gaacttctta acatattgga
     3241 tattaaagca gggcaagatc gtgaaaagcg tgatataagt cactcttttt atcctggttt
     3301 taactctcac gggtgattaa aatttaatct ttggaataac taaaaagata aaaggacacc
     3361 cagatgagta ttcaaagttt gcttgattat atttctgtga tccctgatgg acgacaacaa
     3421 ggaaaagtta gacataaatt atctgatatt ttgctcctca ccgtctgtgc agtaattgct
     3481 ggtgccgatg agtggcagga aattgaagat tttggacatg aaagactgga atggctaaag
     3541 aaatatggtg attttgctaa tggcattccg gtggatgaca ccattgcacg cgttgtgagt
     3601 aacattgaca gtttggcctt tgaaaagatg tttattgaat ggatgcagga atgccatgaa
     3661 atcactgatg gcgaaattat agcaatagat ggaaagacca taagaggctc ctttgataag
     3721 ggaaaaagaa aaggagcaat ccatatggtg agtgcattct cgaccgaaaa tggtattgta
     3781 ctggggtagg tgaaaacgga agccaaaagt aatgaggtta cagccattcc agagttgctt
     3841 aacctactgg atttaaagaa aagtttgata accattgatg ctatgggctg tcagaaagat
     3901 atcgcttcta aaattaaaga taaaaaggca gattatcttc tggcagtaaa aggcaatcag
     3961 gggaaattac atcatgcatt cgaagaaaaa ttccctgtaa aaatgttctc taattataaa
     4021 ggcgattcat ttgatactca ggagataagc catggaagaa aagaaacacg tttacatatt
     4081 atcagtaacg taacgcctga attttgtgat tttgaatttg aatggaaggg attaaaaaag
     4141 ctttgtgtgg cattgtcatt caggtaaaag aaagaagata aatcagcgga aggtttaatc
     4201 attcgatatt acatttcatc aaaggatatg gatgctaaag aatttgcaca tgctatcaga
     4261 gctcactgga aaatcgagaa taatcatcat tgggtgctcg atgtaaaaat gaatgaagat
     4321 ggaagcagaa taagaagagg aaacgcagcc aaaataatat ctggaataaa gaaaatggcc
     4381 ctgaatttat taagagattg caaaggtttt aagggcgggg taaagagaaa aagaaagaag
     4441 gctgcgttaa atacaagtta catagagaaa gtaattgcat cctgcgcaat gcctggattt
     4501 cggtctgaca aaatgaaaaa tttaacacaa atttaattca tgctcttgcc ctgcggttgt
     4561 ggaagtttga actatagaaa tacttaatca acttaagttc taagtatagg aaatgaatag
     4621 aacatgaaat gttttgtagt gtcattgaag aatagtggtc gtagaaaaga ttttgaccat
     4681 agatttaaaa tttttaatta tcaatttttt gacgctatca ctgaatgcac aagtaatcaa
     4741 ttcaactcag ctattgcaaa atcaatatat ggaaggtgtt tgagaaaagg ggagattggt
     4801 tgttcgttga gccattttaa tattattaga gattttgcat taaactccaa agaaaattgg
     4861 ttgctaatca tggaggatga tgctgttcca gagagtcaat ttattcattt tataaatgaa
     4921 tttgaaaata aacatgtaac tacaaacgct gaagtaatat tattaggtca ttcaaaaaca
     4981 agccgtaagc atatatttgt tcaacgtttg aagcagcccc tgcgtaacta taaaaacata
     5041 aacggaataa gttttggtga aaataaaaat gttacccttt gtgggacagt tgcatatcta
     5101 attaataaac aagccgccaa cataatatct ggtaatagcc aaccgtattg gcttgctgac
     5161 gattggttct tattccaaaa tatggggatt agggtttatc atccacaaat tccgctagtg
     5221 tatgaagatc tctcttatga tagctctaca gaaaatgata tttattacca tcacaatttt
     5281 ataaaagaac ccctaaaaaa tatcatacac ataatcatag ggcaatataa attctggaat
     5341 gactctcgaa agttacggaa atcaaataat aaatgagtca tttcggaggg gggcttatga
     5401 agagtgtaaa taattttaat ttttacttgg ctatttttat aggcatgttt gatttaacta
     5461 tttttagcac aggtaatagc ttagggcaag cacttacaac ggtattgtta ttattttcca
     5521 tattaagtga tatcaacaag gtttttttga aaccattttt ttttgttatt tcatacatag
     5581 ttcttgcgct actggtttct ttatttcatg gggagacatc gtatcattat tcatttatta
     5641 ttgttaaaac agggcttatt ctgttcaatg caatggtaat ttcacaaatt ctaattttgt
     5701 atgctgataa aaaacaaatt tcaaattttg ttaattttat ttttctaatc cagaccattt
     5761 cattattatt atattcaaat gaacttttcc aaatgatgcg cggttttttt ctttcagccc
     5821 gctcagagca tctatatgag aattttagtg attcatattg gtacagagat gcaacaatct
     5881 caaatcaagg atattctgga tatgcattag gcgcacttcc tttagtaatt attgccgtcc
     5941 ataacataat gaaatcaaaa ttctttagta ttagatattt tgttgcagta gtgtgttgcg
     6001 gattaggggt gtcagttgca atgttaaatg gtcgttcagt atttttgttt atcccattat
     6061 atatgatata tcttatgctg aggcctaaag aaatatgtct gacatataaa ataattcctg
     6121 ttattctgat tattgtaagt gcaattatta ttgtacttac aaattttgat atatccagta
     6181 attttgtttt ggcttttttt gaacaaaagg ataaatcata tggcatagat tcagttgatg
     6241 atttaatgta taaccatact atcttacatt ttgatataac gttatttggg ttgggaaaat
     6301 atctactttc cgatggttca gcatttgtta gatctgatat tggatactat agacaaatgg
     6361 gagtcggtgg aatatctttg gtgttatttt atattttcag catatggtta gctgtaagat
     6421 atgttatcta tcgtgattta tcattattta ttttattcat aatattactg gctaatttta
     6481 agcaagaagc atttaataat gcaatgttaa tgtatggtgc ttttttacta gcagcatatt
     6541 gggtagctcg ggataaaata gagataacaa agaaatgaag ataattttgt ggcatttggg
     6601 gcgtaaaggt gctgggccaa aatataactt agaaatggca ctagctttaa aaaaagaagg
     6661 ctatgacgta tatgcttgta tttccaagca ggcggaaaat gcaaatgatt ataagaaaca
     6721 taacattaat cacttatcgc ttaatacata tacggggggt gtttccgcat taatcaattc
     6781 tctgcgatta ccttggttga ttaatgaatt taaagattat ttaaagataa atcgtattac
     6841 gcatgtttat tgtacaatgc cgcatatatg gaatttcttc ttttctaaga ggtttaagaa
     6901 attagacata tcctatttgc tcacaattca tgatgcagaa ttacatagtg gtgaggaaaa
     6961 taaattaatt gatattttga tgaaaaaaga tagaaaaaat gcagatggaa ttgttgttct
     7021 tacaaaacat gtaaaagaac aattaaaaaa tttagggaaa tcaattttta taattccaca
     7081 tccagccttt tcatttaata acaataaaaa cagtgcgaaa agtattgtac ccgaccaaaa
     7141 aataaaattg cttttttttg gtaggattca tcactacaaa gggctggata ttcttattga
     7201 tgcatttgaa aaactgaaca aaaaaaataa caggtatagt ctttctatct acggtagtgg
     7261 gaatatctct ccatatcaaa agaaaattct agaactaagc aatattacag tgcataatcg
     7321 ttggatcgat gatgtagaaa ttccttcaat catctctagc catgatgtct gtgttattcc
     7381 ttatcgggat gcaagtcagt caggagtaat tcctacggta atgacttgtg gtgtgcctct
     7441 tgttgtgacc ccggttgctg ggcttaaaga gcaggttgtt cacttacaaa cagcaatatt
     7501 tgcggaagag gtttcttctg attccgttgc aagagcaata gattcattgg ttaaggatat
     7561 atctttgtat gaaaagatat caaagaatgc tctactatac gctcaggaag agatgggatg
     7621 ggaaaaaacc gcatatcgtt ctgtggaagc tcttatctca attactcata attctaaaaa
     7681 gtataatcaa tgatatctac ttcatatgca tgatagtact attgtattca tggcgacaag
     7741 ttataaaaat tggtaattta atgttaggtg atagatgttt caaaatggcg tcaatatatc
     7801 tttttattct ttcattgcaa aggctacggt atttctatgt ggacctttaa cattacttct
     7861 gatctctcat aaattaagta ctgaagagat cgctttttat tataccttct tcaatttaat
     7921 cgcgttacaa caacttgttg aactaggttt aggttttact ctaaaacagt gtatatcaca
     7981 tgcttataaa attgaaaatg atgtatggtt atatgattcg aagaaaatag ttaaatcata
     8041 tatacaattt ggtttgtact ggtttattgg ggtgtcgtgt attattatat ttgtcattgg
     8101 accattggga ttaatctact atggtgatta tgaaggtagt attaagtggc agggggcttg
     8161 gttaggaact ataggtgttc ttgcatttag tataatactg gttccaatac aaattgctat
     8221 tgaagcaaca caaaatcaaa ttgcaatata tcgttgtcaa gttatatatt ctctcacaaa
     8281 tagtttatct ctttgggtat tcatttataa tgactttaag ttatattcca ttcctctaag
     8341 tatgcttata gcaaacatat ttttgttgat tgcactaaaa aatcattata taaaacttta
     8401 taataaatta gcctttgtta aagaaatgga taaattctgg accatctttt ctaaactttg
     8461 gcctttattt tctagagtag caatagtatg gggtgttggt tttctattgt ggaatgggtt
     8521 taatttaatc tcattcaaaa ttttttcgcc tgaagaggct gggagaatta tctttagtat
     8581 tacgttagct cgtgccggat ttactatagc agagtcaatt atttgcgcac aaactactgt
     8641 tgtttcaaat atgatttcta aaggagaaaa tactgaagct gctaagtatt atcgaaaata
     8701 tcaactgatt tcctttgctg ttttaattat agggtacggc ttttattatg ttgtgaagtg
     8761 ttttttttct gatttttact tgtttgacaa attaatgcca aactcattta taacaagtgt
     8821 atttgttttt tttgtattgt tgcttatctt gacaacaaag tgcaatttta ttcgttgtta
     8881 taaaattgaa cctttcgtta aggtttctgt ttggcatggt ctaggtgtgc caatgagttt
     8941 tcttttatca tcgctttatt tcccgatgta tttatatcct tgttcctttg ttctgtttat
     9001 atcaataatt tggtctcagt taatttctaa gcgcatactt tcaaaaatag ggtaaaaaat
     9061 gattaataat tgggttgcat tgatggattc acttaaaaat agccattcgg aaattgctaa
     9121 tttaataggt gaagctagaa tagcttttat agatattccg atgtatttca atgttggtga
     9181 tttattgata tattttggta cggaggcatt tataaaagaa tataacttaa atgttattta
     9241 tcgcacaggc atgaatgttg acttaaaaaa actaaaggat gtagatgtta ttttgtttca
     9301 aggtggaggc aattttggtg atttatatcc acatcatcaa caattacgag agaaaataac
     9361 attaaaattc ccgaataaaa aaataatatg tttgcctcaa acgttacatt ttaataatga
     9421 agaagagcta gagcgatctg ctaaaatatt taagaaacac tcagattttc atctctatgt
     9481 aagagatcag gaaagcctca ctattggtta tcagtttacg gataatataa aacttatacc
     9541 tgatatggcg catagcttgc atccgctcat agacattaat gagtgtgata taaacagaga
     9601 aagttaccgt attctccata tggttcgttc tgataaagaa gcaaattcaa ataatgctaa
     9661 taatatgcta agtaagcgga gctttgattg ggcgaatatc ataagcccaa gtatgtattt
     9721 gatgggtaga agcataatca ttttggataa gttgcgctat agtaatagta tgaagttttg
     9781 ggataaaata gctagcgaca tggtgtttaa atcaattaat tattttatgt cccataatga
     9841 agtttactcc gacagactgc atggtatcat tttggcagct ttattaggga aaaaaataag
     9901 atgctttgat aataattata aaaaaaatag tcgttatatt tcttgctggc taaaggaata
     9961 tccaagctta aaaaatgcta gtgattttta atttcagcta ataaatttca tatatattag
    10021 aaatacatta tacaaatata tatatccgca tatcgcgcgg taaccccctg ataggagtaa
    10081 acaatgtcaa agcaacagat cggcgtcgtc ggtatggcag tgatggggcg caaccttgcg
    10141 ctcaatatcg aaagccgtgg ttataccgtc tctattttca accgttcccg tgagaagacg
    10201 gaagaagtga ttgccgaaaa tccaggcaag aaactggttc cttattatac ggtgaaagag
    10261 tttgttgaat ctctggaaac gcctcgtcgc atcctgttaa tggtgaaagc aggtgcaggc
    10321 acggatgctg ctattgattc cctcaagcca tacctcgata aaggtgacat catcattgat
    10381 ggtggtaata ccttcttcca ggacaccatt cgccgtaatc gtgagctttc tgctgaaggc
    10441 tttaacttca ttggtaccgg tgtttccgga ggcgaagaag gtgcgttgaa aggtccttcc
    10501 attatgcctg gtgggcagaa agaagcctat gagcttgttg cgccgatcct gaccaaaatc
    10561 gccgcagtgg ctgaagacgg tgagccatgc attacctaca tcggtgccga tggtgcaggt
    10621 cactatgtga agatggttca caacggtatt gaatatggtg atatgcaact gattgctgaa
    10681 gcctattctc tgcttaaagg tggcctgaac ctaaccaaca aagaactagc tcagaccttt
    10741 accgagtgga ataacggtga actaagcagc tacctgatcg acatcaccaa agatatcttc
    10801 accaaaaaag atgaagacgg taactacctg gttgatgtga ttctggatga agcagcaaac
    10861 aaaggtacgg gcaaatggac cagccagagt gcgctggatc tcggtgaacc actgtcgctt
    10921 attaccgagt ctgtgtttgc acgttatatc tcgtctctga aagatcagcg cgttgccgca
    10981 tctaaagttc tctctggccc gcaagcgcag ccagctggtg acaaggctga gttcatcgaa
    11041 aaagttcgtc gtgctctgta tctgggcaaa atcgtttctt acgcccaggg cttctctcag
    11101 ctgcgtgctg cgtctgaaga gtacaactgg gatctgaact acggcgaaat cgcgaagatt
    11161 ttccgtgctg gctgcattat ccgtgcgcag ttcctgcaga aaattaccga tgcttatgcc
    11221 gaaaatccgc agatcgctaa cctgctgctg gctccgtact ttaaacaaat tgccgatgat
    11281 taccagcagg cgctgcgcga tgtcgttgct tatgcagtac agaacggtat cccggttccg
    11341 accttcgccg ctgcggttgc ctattatgac agctaccgtg ccgctgttct gcctgcgaac
    11401 ttgatccagg cacagcgtga cta
//
