LOCUS       CR931655               18532 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain Eddy nr. 53 (serotype 11c).
ACCESSION   CR931655
VERSION     CR931655.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18532)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 18532)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..18532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Eddy nr. 53"
                     /db_xref="taxon:1313"
     gene            <1..166
                     /gene="dexB"
                     /locus_tag="SPC11C_0001"
     CDS             <1..166
                     /gene="dexB"
                     /locus_tag="SPC11C_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI33156.1"
                     /db_xref="GOA:Q4K241"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K241"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVP
                     WDAFCVEMTD"
     gene            complement(297..1706)
                     /gene="tnp"
                     /locus_tag="SPC11C_0002"
     CDS             complement(297..1706)
                     /gene="tnp"
                     /locus_tag="SPC11C_0002"
                     /note="member of homology group 17"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1202 transposase"
                     /protein_id="CAI33157.1"
                     /db_xref="GOA:Q4K259"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="UniProtKB/TrEMBL:Q4K259"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRHRNRNRKPKHAIPDEIKERILKKYLSYETYKPNVRHFCELLAEEEGIQLSDT
                     TVRKILYKKNILSPKSHRKTKKRVRKQAKLNPKQPLDNPILPTAEKFLEDPKKVHPSR
                     PRKKFAGELIQMDASPHAWFGAETSNLHLAIDDASGNILGSYFDKQETLNAYYHVLEQ
                     ILANHGIPLQIKTDKRTVFTYQASNSKKMEDDTYTQFGYACHQLGILLETTSIPQAKG
                     RVERLNQTLQSRLPIELERNNIHTLEEANTFLPSYIQTFNEQFGNKTKLSVFEEAPKP
                     SERNLILARLSERVVDSGHHIRFQNRCYIPTEQGKEVYFIRKTKALVIKAFDGDIYLN
                     IADKIYHTKELLNHELYSKNFEQEPEQKKKDASISLHKPIRGNSHLSNNIFIKIKRIM
                     KSLLVRSLILLNYKYSKMK"
     misc_feature    complement(720..1223)
                     /gene="tnp"
                     /locus_tag="SPC11C_0002"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 6.3e-22"
     misc_feature    complement(1590..1655)
                     /gene="tnp"
                     /locus_tag="SPC11C_0002"
                     /note="Predicted helix-turn-helix motif with score
                     1142.000, SD 3.08 at aa 18-39, sequence
                     KTKKRACVELNLSERQINRLLL"
     gene            2052..3005
                     /gene="tnp"
                     /locus_tag="SPC11C_0003"
     CDS             2052..3005
                     /gene="tnp"
                     /locus_tag="SPC11C_0003"
                     /note="member of homology group 39"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1239 transposase"
                     /protein_id="CAI33158.1"
                     /db_xref="GOA:Q4K0X9"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="UniProtKB/TrEMBL:Q4K0X9"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     misc_feature    2133..2198
                     /gene="tnp"
                     /locus_tag="SPC11C_0003"
                     /note="Predicted helix-turn-helix motif with score
                     1087.000, SD 2.89 at aa 28-49, sequence
                     KSNREIAGLLGKAPQTIHNEVK"
     misc_feature    2559..2996
                     /gene="tnp"
                     /locus_tag="SPC11C_0003"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 6.6e-23"
     gene            3128..4573
                     /gene="wzg"
                     /locus_tag="SPC11C_0004"
     CDS             3128..4573
                     /gene="wzg"
                     /locus_tag="SPC11C_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33159.1"
                     /db_xref="GOA:Q4K257"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K257"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVATAFVLLVALIGLLSIIYKKAEKFTIFLLVLSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNIDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDHASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     EFTALANKKHYSIGNVHLDSEEALAFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EVLKNYSRIIDSLQNSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     misc_feature    3128..3244
                     /gene="wzg"
                     /locus_tag="SPC11C_0004"
                     /note="Signal peptide predicted for SPC0483 by SignalP 2.0
                     HMM (Signal peptide probability 0.994) with cleavage site
                     probability 0.469 between residues 39 and 40"
     misc_feature    3332..3679
                     /gene="wzg"
                     /locus_tag="SPC11C_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 1.2e-63"
     misc_feature    3857..4300
                     /gene="wzg"
                     /locus_tag="SPC11C_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 8e-65"
     gene            4575..5306
                     /gene="wzh"
                     /locus_tag="SPC11C_0005"
     CDS             4575..5306
                     /gene="wzh"
                     /locus_tag="SPC11C_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33160.1"
                     /db_xref="GOA:Q4K256"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K256"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLENNRIPTLNNS
                     RYALIEFSMNTPYRDIRSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKSKLFGEPDKFMKKRAQYFLERDLVHVIASDMHNVDGRPPYMAEAYDLVS
                     QKYGEAKAQDLFIDNPQKIVMDQLI"
     misc_feature    4578..5186
                     /gene="wzh"
                     /locus_tag="SPC11C_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1e-38"
     gene            5312..6007
                     /gene="wzd"
                     /locus_tag="SPC11C_0006"
     CDS             5312..6007
                     /gene="wzd"
                     /locus_tag="SPC11C_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33161.1"
                     /db_xref="GOA:Q4K255"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K255"
                     /translation="MMKEQNTIEIDVFQSLKTLWKHKLIILLVALVTGAVAFAYSTFI
                     VKPEYMSTTRIYVVNRNQGDKPGLTNQDLQAGAYLVKDYREIILSQDVLEKVATNLKL
                     DMPAKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDV
                     TTLEEARPATTPSSPNVRRNTLVGFLGGAAVTVITVLLIELLDTRVKRPEDVEDVLQM
                     PLLGVVPDFDKMK"
     misc_feature    5333..5749
                     /gene="wzd"
                     /locus_tag="SPC11C_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 3.3e-51"
     misc_feature    5855..5932
                     /gene="wzd"
                     /locus_tag="SPC11C_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            6017..6706
                     /gene="wze"
                     /locus_tag="SPC11C_0007"
     CDS             6017..6706
                     /gene="wze"
                     /locus_tag="SPC11C_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33162.1"
                     /db_xref="GOA:Q4K254"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K254"
                     /translation="MPTLEISQAKLEPVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKTTTSINIAWAFARAGYKTLLIDADMRNSVMSGVFKPRERITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKFDTSVEKYGSY
                     GNYGNYRKQKK"
     gene            6721..8088
                     /gene="wchA"
                     /locus_tag="SPC11C_0008"
     CDS             6721..8088
                     /gene="wchA"
                     /locus_tag="SPC11C_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33163.1"
                     /db_xref="GOA:Q4K253"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K253"
                     /translation="MNEKLAKLSVVIAQSFLVILLTVLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALAISISNFFSEDRFSISRRGMIYF
                     LLLYVFLVYVLNLFIKWYWRRAYPNFKGSKKFFLLTATSHIEKVLDRLIESDDVVGKL
                     VAVSVLDKPDFQHDYLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDCILAHNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLIL
                     CSLVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEEKKRELMEQNTM
                     QGGMFKVHDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     misc_feature    6721..6807
                     /gene="wchA"
                     /locus_tag="SPC11C_0008"
                     /note="Signal peptide predicted for SPC0487 by SignalP 2.0
                     HMM (Signal peptide probability 0.901) with cleavage site
                     probability 0.304 between residues 29 and 30"
     misc_feature    7504..8085
                     /gene="wchA"
                     /locus_tag="SPC11C_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 2.8e-156"
     gene            8092..8541
                     /gene="wchJ"
                     /locus_tag="SPC11C_0009"
     CDS             8092..8541
                     /gene="wchJ"
                     /locus_tag="SPC11C_0009"
                     /note="member of homology group 26"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33164.1"
                     /db_xref="GOA:Q4K252"
                     /db_xref="InterPro:IPR013969"
                     /db_xref="UniProtKB/TrEMBL:Q4K252"
                     /translation="MKICLVGSSGGHLTHLYLLKPFWKDKERFWVTFDKEDARSILGN
                     ETFYPCHYPTNRNLKNLIKNTILAFNILRKERPDVIISSGAAVAVPFFYLGKLFGAKT
                     VYIEVFDRIDTPTLTGKLVYPVTDKFIVQWDEMKKVYPKAINLGGIF"
     gene            8541..9020
                     /gene="wchK"
                     /locus_tag="SPC11C_0010"
     CDS             8541..9020
                     /gene="wchK"
                     /locus_tag="SPC11C_0010"
                     /note="member of homology group 27"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33165.1"
                     /db_xref="GOA:Q4K251"
                     /db_xref="InterPro:IPR007235"
                     /db_xref="UniProtKB/TrEMBL:Q4K251"
                     /translation="MIFVTVGTHEQQFNRLIKEVDRLKGEGLIQDEVIIQTGFSDYEP
                     VHCQWKALISYDEMNQYMDEADIVITHGGPATFMGVISKGKRPIVVPRQEKFGEHVND
                     HQMEFCLKLLGEGYDLVVIDEIDKLNENIKYSKVQQVSSHNSKFTNELSDIIENMFI"
     misc_feature    8541..9011
                     /gene="wchK"
                     /locus_tag="SPC11C_0010"
                     /note="HMMPfam hit to PF04101, Glycosyltransferase family,
                     score 1.1e-50"
     gene            9162..10274
                     /gene="wcyK"
                     /locus_tag="SPC11C_0011"
     CDS             9162..10274
                     /gene="wcyK"
                     /locus_tag="SPC11C_0011"
                     /note="member of homology group 116"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33166.1"
                     /db_xref="GOA:Q4K250"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K250"
                     /translation="MKILHIPTGGLFSDGIGTFIYSYLECMNLDKWEVTVLATNIPLL
                     EDKAKFENLGIQVVVLERKKTAIIHYMCQLYKLIRANKYDIIHVHGSSSLMSIELSVA
                     KIAGVPVRIAHSHNTTCDHRKLDKVLRPVFHKLYTQAWACGEGAGKWLFTNREYTIIH
                     NARNIKRYQFSESKRQRFRKKLSLKDTTLALGHVGRFNVQKNHEFLVLLMENLVIQGL
                     DVKLFLVGEGSTLSKIKNMVSEKSLEDRVFFLGHLNDMKSFVSAMDIMLLPSLYEGLP
                     LVSVEWQINGIQCILSDTITKECIYTKQVTSLPIRTPLYWEKAIRDFCPEDRLRQSIE
                     NQRLAREAGYDIELELVKLDTLYNKLIMTIKDRTRK"
     misc_feature    9684..10181
                     /gene="wcyK"
                     /locus_tag="SPC11C_0011"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 9.1e-19"
     gene            10271..10741
                     /gene="wcwR"
                     /locus_tag="SPC11C_0012"
     CDS             10271..10741
                     /gene="wcwR"
                     /locus_tag="SPC11C_0012"
                     /note="member of homology group 147"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33167.1"
                     /db_xref="GOA:Q4K249"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="InterPro:IPR005881"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="UniProtKB/TrEMBL:Q4K249"
                     /translation="MKNDRKAQLIITIFKYGKRHVGRSTFYHKLNYKMYQILNAIFVI
                     GIFNTELPASQNISDNIILFHPYGIIVNGDVTLGNNVVIRQQVTIGNKGMERDVGKSP
                     IIEAGVDIGAGAKIIGGITIGEGSKVGANAVVTKSFPPGSILVGVPARNIALEK"
     misc_feature    10490..10543
                     /gene="wcwR"
                     /locus_tag="SPC11C_0012"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 0.0059"
     misc_feature    10571..10624
                     /gene="wcwR"
                     /locus_tag="SPC11C_0012"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 18"
     misc_feature    10625..10678
                     /gene="wcwR"
                     /locus_tag="SPC11C_0012"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 0.99"
     gene            11006..11725
                     /gene="wcrL"
                     /locus_tag="SPC11C_0013"
     CDS             11006..11725
                     /gene="wcrL"
                     /locus_tag="SPC11C_0013"
                     /note="member of homology group 54"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33168.1"
                     /db_xref="GOA:Q4K248"
                     /db_xref="InterPro:IPR007577"
                     /db_xref="UniProtKB/TrEMBL:Q4K248"
                     /translation="MIPKKIHYCWFGGGPLPTDVKKCIDSWRKFCPNYEIIRWDESNF
                     IISDQNNFVQTAYENKAWAFVSDYARLRIIYENGGIYLDTDVELIRNLDELLEHAAFF
                     GAHQINGLVATGLGFGSKKGTKILKELLRLYDNTDFDPCKKNELACPILNSFVFTDFG
                     YQPSSNIVQTEYFTIYPAEYFDPIYVGANARNLLSEKTYSIHHYSASWTPVRVRIKNK
                     IIRYIGRDKILLLKKILERKR"
     gene            11725..12894
                     /gene="wzy"
                     /locus_tag="SPC11C_0014"
     CDS             11725..12894
                     /gene="wzy"
                     /locus_tag="SPC11C_0014"
                     /note="member of homology group 68"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33169.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q4K247"
                     /translation="MKISLSKVFFLQFCALYIFTILYPRGITLTYSPSADFFTLIYKF
                     CLYFTIAASIIYIFIKILYQRLHLASYTFFILQYYIVSIVITLLLTGTIDSGLQSVFY
                     PICIYLFFNEIQDRVLIIKISDIFLYCLTLLFFINILDLMMNFTNIYHITFLGHVQVI
                     SQFGIIAFFISSYYLMIGNRNRKIAFLLQILTVLNCLYADVFLSKVIAIFMIIYALSF
                     NIKRVFWKRGILISFLTFIITILLLFIDIQGYLIRYLQYFDFTFNGRYQIWRIAYQKF
                     LDSKIYGYGVFSFHFNLPWQDSGAKGINYAHNQLMQLAIDNGVIGIVSFFIMIFYMIF
                     LTRKIRNFRVASLFLFSYFCLFIVMFIESVTYYPYYFIILIFQILYERLEQVGEC"
     misc_feature    12499..12693
                     /gene="wzy"
                     /locus_tag="SPC11C_0014"
                     /note="HMMPfam hit to PF04932, O-Antigen Polymerase, score
                     4.4e-09"
     gene            12888..13388
                     /gene="wcwT"
                     /locus_tag="SPC11C_0015"
     CDS             12888..13388
                     /gene="wcwT"
                     /locus_tag="SPC11C_0015"
                     /note="member of homology group 69"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33170.1"
                     /db_xref="GOA:Q4K246"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="UniProtKB/TrEMBL:Q4K246"
                     /translation="MLNSLIRRFNQIFYSYRVRRKAAVAKGRVYTGGKTFVTSNTYLS
                     ENVSFNGMSMFGEGRISIGRNFHSGINCQIITSFHDYDTGTKIPYDNKYIHKDVIIDD
                     NVWIGNNVIILGGSRIGEGAVIQAGSTVVGEIPPGAIAGGHPARVFKFRNMKHYEELK
                     RLEQFY"
     misc_feature    13176..13229
                     /gene="wcwT"
                     /locus_tag="SPC11C_0015"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 0.41"
     misc_feature    13230..13283
                     /gene="wcwT"
                     /locus_tag="SPC11C_0015"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 2.6"
     gene            13398..14585
                     /gene="wcwU"
                     /locus_tag="SPC11C_0016"
     CDS             13398..14585
                     /gene="wcwU"
                     /locus_tag="SPC11C_0016"
                     /note="member of homology group 70"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol phosphotransferase"
                     /protein_id="CAI33171.1"
                     /db_xref="GOA:Q4K245"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="UniProtKB/TrEMBL:Q4K245"
                     /translation="MNIIRYLKRNGFRYALNVLYQYKIQKILDSIVIRFTKFKKLQNI
                     IVIECHTDFDNNGGAFYDYLIRNNYNKKYKIILLLKNRLVRTLPENVDYFYLKKPSLR
                     KSYLLSLSKFFLFDNDILRKYRKDQKHFYLTHGCFPLKNTIGKITVPNYVDFVLSPSG
                     NVDNIIVKQFGLTSKEQCLHTGFPCHDIFYSKPEPLVFLSDYDKKIIWAPTFRKGGGY
                     NRNDSTASYPLGIPLLETLDELANLNIYLSQRDIVLIVKLHPMQDISDLELKQFSHIK
                     FLTNQDLNRKNTNLYQLLMNSDALLSDYSAISYDYLHLDKPIGYVFSDLNDYKLGLSV
                     DNVDDYIAGDKILSFENLLHFIDNIYLEIDKNKEKRKELFNKIFEKQDGESCERLAQI
                     MEL"
     misc_feature    13971..14582
                     /gene="wcwU"
                     /locus_tag="SPC11C_0016"
                     /note="HMMPfam hit to PF04464,
                     CDP-Glycerol:Poly(glycerophosphate) gl, score 6.1e-12"
     gene            14602..16005
                     /gene="wzx"
                     /locus_tag="SPC11C_0017"
     CDS             14602..16005
                     /gene="wzx"
                     /locus_tag="SPC11C_0017"
                     /note="member of homology group 52"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI33172.1"
                     /db_xref="GOA:Q4K244"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K244"
                     /translation="MSVGMKAALWYTVANFIQKGFVFLSTPILTRILNVNDYGTLMLY
                     QSWFVLFAIFATLNLSQAAYNKGLVEFENDKDNFTFSLLFLSKIITIIVAFLYFTFNI
                     LVKDSTGLTPSFMIFLFSDILFNISIEFYLARQRFEFKYRKAILISTSSSFFIVAIST
                     TILLAIKNDLFIKIVLDAIIRIIFGLYCFYLLFFSGRRQLKIEKKYIKYGFSYSLPLM
                     PHFLSHYILNQSDRLMINMFDGREKLAIYSLAYSVSMIMFLFTSAINQSIMPYTFQAL
                     KKKDYCGIHGSTKWLFVVVGGITALSILFAPELIVILGGNKYKESIWLVPPIAISVYF
                     LFVYSMFSNISFYYKMNKLISLVSIGVALSNIILNYIFINIFGYQAAAYTTLLCYILL
                     AFSHFFLYRFLLKKEEIHEELYNMKMILIISLILLIILFLILVIYNLAIIRYAIIAIV
                     LFLLFTKRNKIITSLKS"
     misc_feature    14611..15429
                     /gene="wzx"
                     /locus_tag="SPC11C_0017"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.4e-19"
     gene            16119..16511
                     /gene="gct"
                     /locus_tag="SPC11C_0018"
     CDS             16119..16511
                     /gene="gct"
                     /locus_tag="SPC11C_0018"
                     /note="member of homology group 28"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol-1-phosphate biosynthetic protein
                     Gct"
                     /protein_id="CAI33173.1"
                     /db_xref="GOA:Q4K243"
                     /db_xref="InterPro:IPR004820"
                     /db_xref="InterPro:IPR004821"
                     /db_xref="InterPro:IPR006409"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="UniProtKB/TrEMBL:Q4K243"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQLGDYLIVVVSSDEFNLKE
                     KNKVCYFNFEHRKNLVEAIRYVDLVIPETSWEQKKTDIKEYRIDTFVMGDDWKGKFDY
                     LKEEGVEVVYLPRTKEISTTKIKEDLAD"
     misc_feature    16131..16499
                     /gene="gct"
                     /locus_tag="SPC11C_0018"
                     /note="HMMPfam hit to PF01467, Cytidylyltransferase, score
                     3.4e-29"
     gene            complement(order(16727..17311,17365..17958))
                     /gene="tnp"
                     /locus_tag="SPC11C_0019"
                     /pseudo
     CDS             complement(join(16727..17311,17365..17958))
                     /gene="tnp"
                     /locus_tag="SPC11C_0019"
                     /note="member of homology group 13"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
     misc_feature    complement(join(17231..17311,17365..17577))
                     /gene="tnp"
                     /locus_tag="SPC11C_0019"
                     /note="HMMPfam hit to PF01610, Transposase, score 3.5e-42"
                     /pseudo
     gene            18173..>18532
                     /gene="aliA"
                     /locus_tag="SPC11C_0020"
     CDS             18173..>18532
                     /gene="aliA"
                     /locus_tag="SPC11C_0020"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33175.1"
                     /db_xref="GOA:Q4K242"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K242"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSKSGSSAKAEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    18173..18265
                     /gene="aliA"
                     /locus_tag="SPC11C_0020"
                     /note="Signal peptide predicted for SPC0500 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.629 between residues 31 and 32"
     misc_feature    18419..18487
                     /gene="aliA"
                     /locus_tag="SPC11C_0020"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     5983 a   2711 c   3669 g   6169 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
      121 aatcttagtt ccatgggatg ctttctgtgt ggaaatgact gactagaatg agcaaacctc
      181 aagtttttga agcttgaggt tttttactat agtggattga aactagaata gtgcacctct
      241 gcttctaaaa cattgttaga aatcgatttg actgtcccga tcgatttgtc ctattcttat
      301 ttcattttgc tatacttgta gttgaggaga attaagctcc tcactagtaa actcttcata
      361 atccttttta tttttatgaa gatattgttt gaaagatgtg agtttccacg gatgggtttg
      421 tggagggata tacttgcgtc tttctttttt tgttctggtt cttgttcaaa gtttttcgaa
      481 tagagttcat gatttagtag ctcctttgtg tgatagattt tgtcagcgat attgaggtag
      541 atgtctccgt caaatgcttt tataactaat gctttcgtct ttctgatgaa atagacttct
      601 tttccttgct cggtagggat atagcaacga ttttggaatc ggatatggtg tccactatcg
      661 acgactctct ccgacagtct agctagaatg agatttcgtt cagagggctt aggagcctcc
      721 tcaaagacag agagttttgt cttgtttcca aactgttcat taaaggtttg gatataggaa
      781 ggcagaaagg tattggcttc ttccaaggta tgaatattgt ttcgttccag ttcgataggc
      841 aggcgagatt gtaatgtctg attgagtctt tcgactctcc ctttagcttg agggatagag
      901 gttgtctcaa ggagaattcc cagttggtga caggcgtatc caaattgtgt ataggtgtcg
      961 tcctccattt tcttagagtt ggaggcttga taggtaaaaa cagttctctt atctgtttta
     1021 atttgaagag gaatgccgtg gttggctaag atttgttcga ggacatgata gtaagcattc
     1081 aaggtttctt gtttgtcaaa ataagagcct aggatattgc cagaagcatc atcaatggct
     1141 aggtgtaagt tagaggtttc tgctccaaac caggcatgag ggctggcatc catttggatg
     1201 agttctccag caaatttctt tctgggtcta ctaggatgta cctttttagg gtcttccagg
     1261 aacttttcag ccgtcggtaa gattggattg tctaggggtt gcttggggtt cagtttagct
     1321 tgttttctta ctctcttctt tgtctttctg tgagacttag gcgacaggat atttttctta
     1381 tagagtattt ttctaacagt tgtatcagag agctgaattc cttcttcttc agctagcaat
     1441 tcacagaaat gacggacatt tggtttatat gtttcatagg agaggtattt ctttaggata
     1501 cgttctttga tttcatcagg gattgcatgt tttggttttc gatttctgtt tctgtgtctg
     1561 aaggcttctt ttcctttctg ttgataggct agtagcagac gattgatttg tctttcagaa
     1621 agattgagtt cgacacaggc ccgtttcttt gttttctttc cttgggctat agcttttatc
     1681 acaagatatt ttttcgtttc attcatattc agttggatcc ttttcatatg actattctac
     1741 caaatgggac atttttacgt tcgatttact aaagacatta tcacattcga attgaaagtt
     1801 ctataatgaa gttagccacc ttaccttagt caagaattag atgtttcact atgtttgagt
     1861 aagttgatga tttcatttga taacaggttt gaaactgtta ggctaggtgg ccaaggctaa
     1921 tcatagcctt ggtttagctg aaaaaacagg ttcaagggtt cctgttgtca aatgaaatgt
     1981 gatttaaggt ataagaaaac acctctgtgc tatacttgtt gttcaccaca aacacaagga
     2041 aaggcacaga gatgcaagaa cattataccc caaaagggaa acatttgaca atagataacc
     2101 gtcgcttgat tgagcggtgg aagaatgaaa ataagtccaa tcgtgaaatt gcaggcttgt
     2161 taggaaaggc gcctcaaacg attcataatg aagtcaaaag aggtacaact ttacaacaag
     2221 tgagaaaagg gctatacaaa aaggtctatt ctgccgatta cgcacaaact gtttaccaat
     2281 tcaatcgaaa acggtcggtg aaaaagttaa ttttaacaaa ggaaatcaga gagaagatct
     2341 tacactatca taagcaaaaa ttttcgcctg aaatgatggt taacaagaag caagtgaaag
     2401 ttggtatttc aaccatctac tactggtttc ataatggtca tttaggattg acgaaggccg
     2461 acatgcttta tcccagaaaa aggaaaggtg tcaagaagca agctagtccg aactttaagc
     2521 cggcaggtaa atctatcgaa gaacgtcctg acgttattaa tcttcgcttg gaaaatggtc
     2581 attatgaaat tgataccgtc ctactgacta agataaaaaa ttattgcctg ttagtcttaa
     2641 ccgaccggcg gagcagacac caaattataa ggttaattcc aaataaaact gctgaatctg
     2701 tcaatcaggc gcttacgtta ctattagggg agcatcgtat tctgtccatt actgcagata
     2761 atggttcgga gttcaaacga ttgtctgagg tatttcctga ggaacatatc tactacgcac
     2821 atgcttactc ttcatgggag agaggttcaa atgaaaatca taatcgatta attcggagat
     2881 ggttacctaa aggaaccaag aaaacgactc cgaaagaagt agcttttatc gaaaattgga
     2941 ttaacaacta ccctaaaaaa tgcttggact acaagtcgcc aagtgaattt cttttgggtg
     3001 gctaacttca acttgaaatt tgggatcaca ttcgaattac acaagatgca gatagtgaga
     3061 aaaaggtgta gacattaccg taaaaaagtg atataattgt aagatgttca atgtataggt
     3121 gttaatcatg agtagacgtt ttaagaaatc aggttcacag aaagtgaagc gaagtgttaa
     3181 tatagttttg ttgactattt atttattgtt agtttgtttt ttattgttct taatctttaa
     3241 gtacaatatc cttgctttta gatatcttaa tctagtggca actgcctttg ttctactagt
     3301 tgccttaata gggctactct cgattatcta taaaaaagct gaaaagttta ccattttttt
     3361 gttggtgctc tctattcttg tcagctcagt gtcgctcttt gcagtacagc agtttgtggg
     3421 actgaccaat cgtttaaatg cgacttctaa ttactcagaa tattcgctca gtgtcgctgt
     3481 tttagcagat agtgagattg agaatgttac gcaactgacg agtgtgacag caccgactgg
     3541 gactgataat gaaaacattc aaaaactact agctgatatc aaatcaagtc agaatatcga
     3601 tttgacggtt aatcaaagtt cgtcttactt ggcagcttac aagagtttga ttgcaggaga
     3661 gactaaggcc attgtcttaa atagtgtctt tgaaaatatc attgaatcgg agtatccaga
     3721 tcacgcatcg aagataaaaa agatttatac caagggattc actaaaaaag tagaagctcc
     3781 taagacttct aagaatcagt ctttcaatat ctatgttagt ggaattgata cttatggtcc
     3841 aattagttcg gtgtcgcgtt cagatgtcaa tatcttgatg actgtcaatc gagataccaa
     3901 gaaaatcctc ttgaccacaa cgccacgtga tgcttatgta ccaatcgcag atggtgggaa
     3961 taatcaaaaa gataaattaa cccatgcagg tatttatgga gttgattcgt ccatccacac
     4021 cttagaaaat ctatatggag tggatatcca ttactatgtc cgtttgaact tcacttcttt
     4081 cttgaagttg atcgatttgt tgggtggggt agatgtttat aatgatcagg aattcacagc
     4141 tcttgctaat aaaaaacact attctattgg taatgtccat ttagattcag aagaggcact
     4201 cgcttttgtt cgtgagcgct actctctagc agatggtgat cgtgaccgtg ggcgcaatca
     4261 acaaaaggtg attgtggcta tccttcaaaa attaacttcg accgaagtgc tgaaaaatta
     4321 tagcagaatc attgatagct tgcaaaattc tatccaaaca aacatgcccc ttgagactat
     4381 gataaacttg gtcaatgctc agttagaaag tggtggaacg tacaaagtaa attcgcaaga
     4441 cttgaagggt aggggacgga cggatcttcc ttcctatgcg atgccagata gtaacctcta
     4501 tatgatggaa attaacgaca gtagccttgc atctgtcaaa actgctattc aggatgtgtt
     4561 ggaggggaga tgaaatgatt gatattcatt cgcacattgt ctttgatgta gatgatggtc
     4621 ccaagtcaag agaggaaagt aaggctctct tgacagaagc ctacaggcag ggggtgcgaa
     4681 ccattgtctc tacctctcac cgtcgcaagg gcatgtttga aactccagaa gagaagatag
     4741 cagaaaactt tcttcaggtt cgggaaatag ctaaggaagt cgcgagtgac ttggtcattg
     4801 cttatggggc tgaaatttac tacacaccag atgttttgga taagctggaa aataatcgga
     4861 ttccgaccct caataatagt cgttatgcct tgatagagtt tagtatgaac accccttatc
     4921 gcgatattcg tagtgccttg agtaaaatat tgatgttggg aattactcca gtcattgccc
     4981 acatcgagcg ctatgatgct cttgaaaata atgaaaaacg cgttcgagag ctgatcgata
     5041 tgggctgtta cacgcaagta aatagttcac atgtcctcaa atccaaactt tttggagaac
     5101 ctgataaatt catgaaaaaa agagcgcagt atttcttgga gcgtgatttg gttcatgtga
     5161 ttgcaagtga tatgcataat gtggacggca gacctcctta tatggcagaa gcatatgacc
     5221 ttgtttccca aaaatacgga gaagcgaagg ctcaggacct ttttatagac aatcctcaaa
     5281 aaattgtaat ggatcaacta atttaggaga aatgatgaaa gaacaaaaca cgatagaaat
     5341 cgatgtattt caatcactta aaaccttatg gaaacacaag ctaatcattt tattagtggc
     5401 acttgtgaca ggggcggtag cctttgcata tagcactttt attgttaagc cagaatatat
     5461 gagcaccacg cgtatttacg tagtcaaccg taatcaagga gataagccag gactgacgaa
     5521 tcaggacttg caggcaggag cttatctggt aaaagactac cgcgaaatta tcctttcgca
     5581 agatgtattg gaaaaggtag cgacaaactt gaaattggat atgccagcaa aaacgttaac
     5641 tagcaaagtg caagtgactg taccagccga cactcgtatc gtctcaatct ctgtcaagga
     5701 taaacaacca gaggaagcca gtcgcattgc taattctcta cgagaagttg ctgcagaaaa
     5761 gatcatcgct gtaacgcgag tatctgatgt aacgacgctt gaagaagcgc gaccagctac
     5821 gactccctct tctccaaatg ttcgacgcaa caccttagtt ggttttcttg gaggagccgc
     5881 cgtaacagta attactgttc ttttgattga gttgctcgat acccgtgtaa aacgtcctga
     5941 agatgttgaa gatgtactgc aaatgccact tctaggagtc gttccagatt ttgataaaat
     6001 gaaataggag gaagttatgc caacgttaga aatctcacag gcgaaattag aacctgtgaa
     6061 aaaggcagag gaatattata atgctttgtg cacgaaccta cagttaagtg gagatgattt
     6121 gaaagtattt tctatcactt ctgtgaaagc aggagaagga aaaacaacga cttccatcaa
     6181 tatcgcttgg gcttttgcgc gtgcaggtta caaaacgctg ctgattgatg cagacatgcg
     6241 taactccgtg atgtcaggtg tctttaaacc aagggaaagg attactggac taacagaatt
     6301 tctatcaggg acaacagacc tgtcacaggg gctttgcgat accaatattg agaatctctt
     6361 tgtgattcag gctggttctg tgtcaccaaa tccgacagcc cttcttcaaa gtaagaattt
     6421 cagtacaatg cttggaacct tgcgtaaata ttttgactat atcgtcgtag acactgctcc
     6481 tatcggtatc gtgattgatg cggctatcat tatgcagaaa tgtgatgctt ctattttagt
     6541 gacgaaggca ggtgaaacaa aacgacggga tcttcaaaaa gcgaaagaac agttggaaca
     6601 aactgggaag tcgtgtttag gagttgtgtt gaataaattt gatacttcag tagagaaata
     6661 cggttcttat gggaattatg ggaattacag gaaacagaaa aaataggttg agggatagag
     6721 atgaatgaaa aattagcaaa gctttcagta gtcatagccc agagttttct tgttattcta
     6781 ttgactgttc tacttagcgc tgtgagagaa acagagattg tttcaacaac agctattgta
     6841 ctttatatcc tccactattt tgtcttttat atcagtgatt atggacggaa tttctttaaa
     6901 aggggatatt tgattgaact tgtccagaca ttgaaatata tcctattctt tgcgctagcg
     6961 attagtattt ctaatttttt ctcagaagat cgatttagta tttccagaag aggcatgatt
     7021 tacttcctct tattatatgt tttcttagtc tatgtgctaa acctatttat caagtggtat
     7081 tggaggcggg cttatcccaa ctttaaagga agtaagaagt ttttcctact tacagcaact
     7141 tctcatatcg aaaaggtact ggatagacta atagaatcag atgatgttgt tgggaagttg
     7201 gtagccgtca gtgttttaga taaaccagat tttcagcacg attatttaaa ggttgtagca
     7261 gagggggaga tcgtaaactt tgcgactcat gaggtggtcg atgaagtctt tatcaatctt
     7321 ccaagtgaaa aatacaatat tggagagctt gtctctcagt ttgaaacgat gggaattgat
     7381 gtaacagtca atctaaatgc tttcgattgt atcttggcac ataacaagca aatttgtgag
     7441 atggcaggac taaatgttgt gactttttct acaacatttt ataagactag ccatgtgatt
     7501 gctaagcggg ttattgatat tatcggttcc ctggtaggtt tgatactatg tagtctagtc
     7561 agtattgtgc tggttccttt gattcgaaag gatgggggct ctgctatttt tgctcagacg
     7621 cgtataggaa aaaatggccg ccatttcact ttttataagt ttcgctccat gtgtgtagat
     7681 gctgaggaga aaaaaagaga actcatggaa caaaatacca tgcagggtgg aatgtttaag
     7741 gtgcacgatg atcctcgtat cacgaaaatt ggtcgtttta tacggaagac gagcttggac
     7801 gagctaccac agttttataa tgttctaaag ggagatatga gtttggttgg cacacggcca
     7861 ccaacagtgg acgagtatga acactatacc ccagaacaaa aacgtcggct aagttttaaa
     7921 cctggtataa caggcttatg gcaggtcagt ggacgaagtg aaatcaaaaa tttcgatgaa
     7981 gttgtcaaat tagatgtggc ctatatagac gattggacaa tctggaaaga tattgagatt
     8041 ttattgaaga cagttaaagt tgtattgatg aaggatggag ctaaatagga aatgaaaata
     8101 tgtttagttg gatctagtgg aggtcatctg actcatttat atctattaaa acctttctgg
     8161 aaagataagg aaagattttg ggttactttt gataaagagg atgcaagaag tatcttggga
     8221 aatgaaacat tttatccttg tcattatcct actaatcgta atttgaaaaa tcttattaaa
     8281 aatacgattc ttgctttcaa tattttgaga aaggaacgcc ctgatgttat catctcatca
     8341 ggggctgctg tagcagttcc tttcttttac ctaggaaaac tatttggtgc taagacagtc
     8401 tatattgaag tttttgaccg tattgatacg ccaacattaa cagggaaatt ggtatatcca
     8461 gtgacagata agttcatagt tcagtgggat gaaatgaaaa aagtatatcc gaaagcaatc
     8521 aacctcggag ggattttcta atgatttttg tgacagtagg tactcatgag caacagttta
     8581 atcgacttat taaagaggtt gatagattaa aaggtgaggg acttattcag gatgaagtta
     8641 ttattcagac tggtttttcg gattatgaac cagtgcactg ccaatggaaa gctttgattt
     8701 cttatgatga gatgaatcaa tatatggatg aagcagatat tgtcattaca catggtggcc
     8761 cagcaacatt tatgggagtg atttctaagg ggaagagacc gattgtagta cctagacaag
     8821 aaaaatttgg cgagcatgtg aatgatcacc aaatggaatt ttgcttaaag ttactaggcg
     8881 aaggatacga tctagttgta atcgatgaaa ttgataaact taatgagaat attaaatatt
     8941 caaaagttca gcaagttagt tctcataata gtaagtttac taatgaactg tcagatataa
     9001 ttgaaaatat gtttatataa gatatgtgtg actgccggtt ttttgtgtta ctaataattg
     9061 tcatacagtc agagcttttt aaactatatc gttattaaat agtgagtttt atattttaat
     9121 gattaccatt cgtatttaat aagaaataat ggagaagatg aatgaagatt ttgcatattc
     9181 caacaggtgg cttattttca gatggaatag ggacgtttat ctattcttat ttagaatgca
     9241 tgaatctaga taaatgggaa gtgacagttt tagctactaa tattccactg ttagaagata
     9301 aagcaaaatt tgagaattta ggtatccagg tagtagttct agagcggaaa aaaactgcga
     9361 ttattcacta tatgtgtcaa ttatacaaat taataagagc taataaatat gatataattc
     9421 atgttcatgg tagtagttct ttaatgtcaa tcgagctatc tgttgcaaaa attgcagggg
     9481 ttccagtaag gattgcccat agtcataata ctacttgtga ccatagaaaa ttagataaag
     9541 tattacggcc agtatttcat aaattatata cgcaggcgtg ggcatgtggt gaaggagctg
     9601 ggaaatggct ttttaccaat agagaatata ctattattca taatgcaaga aatataaaac
     9661 gttatcaatt tagtgagtcc aaacgacaac gatttagaaa aaaactatct cttaaagata
     9721 caactcttgc tttaggtcat gttggtcgct ttaatgttca aaaaaatcat gaatttcttg
     9781 tgttattaat ggaaaattta gtaatacaag gactagatgt taaattattt ttagtaggtg
     9841 aagggtcaac tttatcaaaa attaagaata tggtttctga aaaatcttta gaagataggg
     9901 tcttcttttt aggtcatctt aatgatatga aatcatttgt gtctgctatg gatataatgc
     9961 ttctcccaag cttgtacgaa ggtctccctc tggtgtcagt agaatggcaa ataaatggaa
    10021 tacaatgtat cttatctgat actataacaa aggagtgtat ctacactaaa caagtgactt
    10081 ctttaccaat taggacccct ctttattggg aaaaagcgat aagagatttc tgtccagaag
    10141 atagattgag acaatcaatt gagaatcaaa gacttgcgag agaagctggt tatgatattg
    10201 aactggaatt agttaaattg gatactttat acaataaatt gataatgact ataaaagata
    10261 ggacaagaaa atgaaaaatg ataggaaagc tcaactaata attacaattt ttaaatatgg
    10321 taaaagacat gtaggacggt caacttttta tcataagtta aattataaaa tgtatcaaat
    10381 tttaaatgct atatttgtaa ttggtatttt caatacagaa ttaccagcat cacaaaatat
    10441 tagtgataat ataatattgt ttcatccata tgggataata gttaatggcg atgtaacttt
    10501 agggaataat gttgtgataa gacagcaggt taccattggt aataaaggga tggaaaggga
    10561 cgtgggaaaa tctcctatta tcgaagcagg tgttgatatt ggagcaggtg ctaaaattat
    10621 aggagggata acgattggtg agggttcaaa agtaggagct aatgctgttg taacaaaaag
    10681 ctttccacct ggttcaattt tagtaggagt tccagcgagg aatatagcat tagagaagta
    10741 atttgggata gaatgcaaat aagtgtgtta atacactaag atattggcat cagcgacaat
    10801 gctgtttgaa tattttagtg aatcaaaaaa gagagaaaaa tgataaaatt taacttagta
    10861 agcattatat catatgttca ataagaactg tcgaattaat ttaataaatt tagtgataaa
    10921 tacgtactag tgagaatttg ttttattgta agagagttcc tataattata gataattact
    10981 aaatagtcag ggaaaggaaa aactaatgat tccaaaaaaa atacattatt gctggtttgg
    11041 tggaggtcca ttacctactg atgttaaaaa atgtattgac agctggagaa aattttgtcc
    11101 gaactatgag attattagat gggatgaaag caatttcatt attagtgatc aaaacaattt
    11161 tgttcagact gcatatgaaa acaaagcttg ggcatttgtt agcgactatg cacggttaag
    11221 aatcatatat gaaaatggtg gcatctattt ggatacagat gttgaattga ttagaaatct
    11281 tgatgaattg cttgagcatg cagctttttt tggtgctcac cagataaatg gattagtagc
    11341 tactggtcta ggttttggtt cgaaaaaggg gacgaagata ttaaaagaat tattaagact
    11401 gtatgataat acagattttg atccgtgtaa aaagaatgag ttggcatgtc ccatacttaa
    11461 ttcgtttgtc tttactgatt ttggctatca gccttcttct aacattgttc aaacggagta
    11521 ttttactatc tatcctgctg agtattttga tcctatatat gttggagcca atgctagaaa
    11581 tttattatcg gagaaaacat attcaattca tcattacagt gcctcttgga ctcctgtgag
    11641 agttagaata aaaaataaga tcattagata tattggtagg gataagattc tactattaaa
    11701 gaaaattcta gaaaggaaaa gataatgaaa atatcgcttt ctaaagtatt ttttttacaa
    11761 ttttgtgcac tttatatctt tacaatttta tatcctagag gtattacatt aacttattct
    11821 ccatctgcag atttttttac tctgatttat aaattttgtt tatatttcac catcgcagcc
    11881 agtataatat atatatttat aaaaatatta tatcagagac tacacctagc atcatatact
    11941 ttttttatat tgcagtatta tattgtttct atagttatta cattgctttt aacaggcaca
    12001 atagattcgg gtttacaatc agtcttttat ccgatctgta tatatttatt ttttaatgag
    12061 attcaagata gggtattgat tataaaaatt agtgatatat ttttatactg tttaactctt
    12121 ttattcttta taaatatttt ggatcttatg atgaatttta ccaatattta tcatataacc
    12181 tttttggggc atgtccaagt gatatcacaa tttggaatta tagctttttt catttcttcc
    12241 tattacttaa tgataggaaa tagaaatcgc aagatagcct tcctattaca aattttgact
    12301 gtgctcaatt gtctatatgc tgatgttttt ttatcaaagg ttatagcaat cttcatgatt
    12361 atttacgcat tatcatttaa cataaagaga gtattttgga agagagggat tctaatttct
    12421 ttcttgacat ttattataac tattctgctt cttttcattg atattcaagg ttatttgata
    12481 agatatttac aatattttga ttttactttt aatggccgct atcaaatttg gcgtattgct
    12541 tatcaaaaat ttttagattc aaaaatatat ggctatggag tttttagctt tcatttcaat
    12601 cttccgtggc aagattctgg tgctaagggg atcaactatg ctcataatca gcttatgcaa
    12661 ttagcaatag ataatggagt aattggtatc gtctctttct ttattatgat tttttatatg
    12721 atatttttaa caaggaagat tagaaatttt agagtagctt cattgttttt attttcgtac
    12781 ttttgtttgt ttatagtaat gtttattgaa agtgtaacct attacccgta ttactttatt
    12841 atattgattt ttcaaatatt atatgaaagg ttagagcagg tgggagaatg ctaaatagtt
    12901 taattagaag atttaatcag attttctata gttatcgggt tagaagaaaa gctgcagttg
    12961 ctaaaggaag agtgtacacg ggtggaaaaa catttgttac ttcgaatacc tatctttctg
    13021 agaatgtttc ttttaatggc atgtcaatgt ttggagaagg tagaatttcg ataggaagaa
    13081 atttccattc tggtataaat tgccaaatta taacgtcatt tcatgactat gatacaggaa
    13141 ctaagatacc atacgacaat aagtacatac ataaagatgt aattattgat gataatgtgt
    13201 ggattgggaa taatgttatt atcctcggcg gatctcgtat cggagaagga gcagttattc
    13261 aagcagggag tacagttgta ggggaaatac ctccaggagc aatcgcaggt ggtcatccag
    13321 caagagtatt taaatttagg aatatgaagc attatgaaga attaaagaga ctagaacaat
    13381 tttattagga gctatatatg aatattataa gatacttgaa aagaaatgga tttcgatatg
    13441 cattaaatgt cctctatcaa tataaaattc aaaagatttt agattcaatt gttattagat
    13501 ttactaagtt taaaaagtta caaaatatta ttgtcattga atgtcacaca gactttgata
    13561 ataatggagg agctttttat gattatttga taagaaataa ttataataag aaatataaaa
    13621 ttattttatt attaaaaaat cgactagtac gtactcttcc tgaaaatgta gattattttt
    13681 acttgaaaaa acctagtttg aggaagtcat atttgttatc attaagtaaa ttttttcttt
    13741 tcgataatga tatacttcgt aaatatagaa aagatcaaaa acacttctat ttaacacatg
    13801 gatgctttcc tttaaaaaat acaataggta aaataacagt tccgaattat gttgattttg
    13861 ttctatctcc ctcgggcaat gtagataata ttatagttaa gcagtttgga ttaacatcta
    13921 aagagcaatg tcttcacact ggatttccgt gtcatgatat cttttattca aaaccagaac
    13981 ctctagtatt tttatctgat tatgataaaa aaattatctg ggcaccaact tttagaaagg
    14041 gtggtggcta taatagaaat gatagtacag ctagctatcc tttaggtatt ccgttacttg
    14101 aaacactaga tgaacttgca aacctaaata tatatctaag ccaacgggat attgtcctga
    14161 ttgtaaagtt acatccaatg caagatattt cagatttgga gttgaaacaa tttagtcata
    14221 ttaagtttct gacaaatcaa gatttgaatc gtaaaaatac aaatctgtat caattgctga
    14281 tgaattcaga tgctttactc agtgactatt ctgcaatctc gtatgattat ttacaccttg
    14341 ataaaccaat agggtatgtt ttttcggatc taaatgatta taagttgggg ctttcagttg
    14401 ataatgtaga tgattatata gcaggtgata agatactgtc ttttgaaaac ttgctgcact
    14461 ttattgataa catttatcta gaaattgata aaaataaaga aaaacgcaaa gaattattta
    14521 ataaaatatt tgaaaaacag gatggagaat cgtgtgaaag attggcacaa attatggaat
    14581 tataaaagcc gttacgaaga aatgtctgtc gggatgaaag cggcactctg gtatactgtt
    14641 gcaaatttta ttcaaaaggg ttttgtattt ctttcaactc caattttaac cagaatactt
    14701 aatgttaatg attacggtac attgatgctt taccaatcat ggtttgtact atttgctatt
    14761 tttgcgacct tgaatctttc tcaagcagct tataataagg gattagtaga atttgagaat
    14821 gataaagata attttacatt ttctttgttg tttttgtcta agattattac tataattgtt
    14881 gcttttttat attttacttt taatatactg gttaaagata gtactggatt aactcccagt
    14941 ttcatgatat ttttattcag tgatatttta tttaatatca gtatagaatt ttatttggca
    15001 cgtcagagat ttgaattcaa atatagaaaa gcaattctaa tttcaacttc ttcaagtttt
    15061 tttattgtag ctattagtac aactatctta ttagcgatta agaatgattt attcattaaa
    15121 attgtattag atgctattat ccgaattatc tttggtttat attgttttta tctcttgttt
    15181 ttttcaggga gaagacaact taagatagaa aaaaaatata ttaaatatgg ttttagttat
    15241 tcattacctt tgatgccgca tttcttatcg cactatattt tgaatcagtc tgaccgtttg
    15301 atgattaaca tgtttgatgg tagggagaaa ttagctatat atagtctagc ttattctgta
    15361 tcaatgatta tgtttttgtt tactagtgca attaatcaat caataatgcc gtatacattt
    15421 caagctttga aaaaaaagga ttattgtggg atacatggga gcaccaaatg gctttttgta
    15481 gtagttgggg ggatcacagc tctctcaatt ctatttgcac cagaactaat tgttatttta
    15541 ggcggcaata aatataagga atcaatttgg ctagtaccac caattgccat ctcggtttat
    15601 ttcctttttg tatattctat gtttagtaat atcagctttt attataagat gaataagttg
    15661 atttcgttag tttccatagg tgtggctctt tcaaatatta ttttaaatta tatttttatt
    15721 aatatatttg ggtatcaagc tgcagcttac actacattat tatgctatat attgttagcg
    15781 ttttctcatt ttttcttata tagattttta ttaaaaaaag aggaaattca tgaggaactt
    15841 tataatatga agatgatttt aataatatct ttaatattat taataatact atttttgata
    15901 cttgttattt ataacttagc cattataaga tatgcaatta ttgcaattgt tttatttctt
    15961 ttgtttacaa agagaaataa aataattaca tcgctaaaaa gttgatattg aaaatttaga
    16021 atcaaattaa gaatatagtg aatatcaaac tagtattaat aatgaataat tgtttttatg
    16081 taatttagga ttaataaaaa aattgaaagg aaatatcaat gaaaagagta attacttatg
    16141 gaacctttga tttgcttcat tatggacata tcaatttgct aaagagagca aagcaattag
    16201 gagattatct cattgttgta gtttcaagtg atgagttcaa tttgaaagaa aaaaataaag
    16261 tttgttactt taattttgaa catagaaaga atttggttga agcaataaga tatgttgatc
    16321 tggtaattcc tgaaacaagc tgggaacaga aaaaaacaga tattaaagaa tatcgcattg
    16381 atacatttgt tatgggggat gattggaaag gaaaatttga ttatttaaaa gaagaaggag
    16441 tggaagtagt ttatttacca agaactaaag aaatatctac aactaaaatt aaagaagatt
    16501 tagcagatta gattttttac aaaaatattt tgagatcaga taataaattt gttttcataa
    16561 ttattaatgt ctattgtttt attaccacag aagtatatta aattaaaata aattatttta
    16621 gatttataat gtggctcctt gtcaacgaac atctggagag gacaatcact gtcttctcct
    16681 ttttattttt ttggctcttt gtcaactgta gtgggttgaa aaaaagctaa gctcgagaaa
    16741 ggacaaattt tgtcctttct tttttgatat tcagagcaat aaaaatccgt tttttgaagt
    16801 tttcaaagtt tcgaaaacca aaggcattgc gcttgataag tttgatgaga ttattggtcg
    16861 cttccagttt ggcgttggaa taaggtaatt gaagggcgtt gataatcttt tctttatctt
    16921 tgaggaaggt tttaaagaca gtctgaaaaa taggatgaac ctgcttaaga ttgtcctcaa
    16981 taagtccgaa aaatttctct ggttccttat tctggaagtg aaaaagcaag agctgataga
    17041 gctgatagtg gtgtttcaag tcttccgaat agctcaaaag cttgtttaaa atctctttat
    17101 tggttaagtg catacgaaaa gtaggacgat aaaaacgttt atcactcagt ttacggctat
    17161 cctgttgaat gagtttccag tagcgcttga tagccttgta ttcatgggat tttcgatgaa
    17221 actgattcat gatttgaaca cgcacacgac tcatagcacg gctaagatgt tgcacaatgt
    17281 gaaagcgatc aagaacgatt ttagcattcg ggagtgaaac agtctgggag actgtttcag
    17341 cctgagccta gaaatttgaa agcgaagctg tttagctaag tcatagtaag ggctaaacat
    17401 atccatagta ataattttga cgcgacatag gacaactcta tcgtagcgaa gaaagtgatt
    17461 tcgaatgata gcttgtgttc ttccctcaag aacagtgatg atattgagat tgttaaaatc
    17521 ttgcgcaatg aagctcatct ttccctttgt aaaagcatac tcatcccaag acataatctc
    17581 aggaagacaa gaaaaatcat gtttaaagtg aaaatcattg agcttacgaa tagcagttga
    17641 agttgagatg gaaagctgat gggcaatatc agtcatagaa atcttttcaa ttaacttttg
    17701 agcaatcttt tggttgatga tacgagggat ttggtgattc ttcttgacga tagaagtttc
    17761 agcgaccatc atttttgaac agtgatagca cttgaaacga cactttctaa ggagaattct
    17821 agtaggcata ccagtcgttt caagataagg aattttagaa ggtttttgaa agtcatattt
    17881 cttcaattgg tttccgcact cagggcaaga tggggcgtcg tagtccagtt tggcgatgat
    17941 ttccttgtgt gtatccttct aatgagttgt tttgtcgctt ttcattatag gtcatatggg
    18001 actttttttc tacacaaaaa taggctccat aatatctata gtggatttac ccactacaaa
    18061 tattatagag tctttttttc agaatttacc aaattaatta aaaaattcag aaaattctat
    18121 tgacatctct ctgaaaagag tctataatag agagaaagtt ttaaaggaga agatgatgaa
    18181 aagttcaaaa ctatttgccc ttgcgggtgt aaccttattg gcggcgacta ctttagctgc
    18241 atgttctaaa tcaggttcga gcgctaaagc tgagaagaca ttctcataca tttatgaaac
    18301 ggatcctgac aacctaaact acttgacaac tgctaaggct gcgacagcaa atattaccag
    18361 taacgtggtt gatggtttgc tagaaaatga tcgctacggg aactttgtgc cgtctatggc
    18421 tgaggattgg tctgtatcca aggatggatt gacttacact tatactatcc gtaaggatgc
    18481 aaaatggtat acttctgaag gtgaagaata cgcggcagtc aaagctcaag ac
//
