LOCUS       CR931663               18517 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 389/39 (serotype 15a).
ACCESSION   CR931663
VERSION     CR931663.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18517)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 18517)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..18517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="389/39"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC15A_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC15A_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI33333.1"
                     /db_xref="GOA:Q4K1T1"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K1T1"
                     /translation="SNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            294..467
                     /gene="aliB"
                     /locus_tag="SPC15A_0002"
                     /pseudo
     CDS             294..467
                     /gene="aliB"
                     /locus_tag="SPC15A_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
                     /db_xref="PSEUDO:CAI33334.1"
     gene            complement(435..980)
                     /gene="tnp"
                     /locus_tag="SPC15A_0003"
                     /pseudo
     CDS             complement(435..980)
                     /gene="tnp"
                     /locus_tag="SPC15A_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            1202..2647
                     /gene="wzg"
                     /locus_tag="SPC15A_0004"
     CDS             1202..2647
                     /gene="wzg"
                     /locus_tag="SPC15A_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33336.1"
                     /db_xref="GOA:Q4K1R4"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K1R4"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYDILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AIPDSNLYVMEIDDSSLAVVKAAIEDVMEGR"
     misc_feature    1202..1318
                     /gene="wzg"
                     /locus_tag="SPC15A_0004"
                     /note="Signal peptide predicted for SPC0676 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.649 between residues 39 and 40"
     misc_feature    1406..1753
                     /gene="wzg"
                     /locus_tag="SPC15A_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 6.7e-65"
     misc_feature    1931..2374
                     /gene="wzg"
                     /locus_tag="SPC15A_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 3.5e-70"
     gene            2649..3380
                     /gene="wzh"
                     /locus_tag="SPC15A_0005"
     CDS             2649..3380
                     /gene="wzh"
                     /locus_tag="SPC15A_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33337.1"
                     /db_xref="GOA:Q4K1R3"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K1R3"
                     /translation="MIDVHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFVDNPRKIIMDQLI"
     misc_feature    2652..3260
                     /gene="wzh"
                     /locus_tag="SPC15A_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 2.9e-36"
     gene            3389..4081
                     /gene="wzd"
                     /locus_tag="SPC15A_0006"
     CDS             3389..4081
                     /gene="wzd"
                     /locus_tag="SPC15A_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33338.1"
                     /db_xref="GOA:Q4K1K7"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K1K7"
                     /translation="MEEQNTLEIDVLQLFRSLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRDQGEKSGLTNQDLQAGTYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGLVPDLDKMK"
     misc_feature    3407..3823
                     /gene="wzd"
                     /locus_tag="SPC15A_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1.7e-52"
     misc_feature    3929..4006
                     /gene="wzd"
                     /locus_tag="SPC15A_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4091..4780
                     /gene="wze"
                     /locus_tag="SPC15A_0007"
     CDS             4091..4780
                     /gene="wze"
                     /locus_tag="SPC15A_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33339.1"
                     /db_xref="GOA:Q4K1K6"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K1K6"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            4795..6162
                     /gene="wchA"
                     /locus_tag="SPC15A_0008"
     CDS             4795..6162
                     /gene="wchA"
                     /locus_tag="SPC15A_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33340.1"
                     /db_xref="GOA:Q4K1R0"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K1R0"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGKL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLASIVLVPLIRKDGGSTIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVFM
                     RDGAK"
     misc_feature    4795..4887
                     /gene="wchA"
                     /locus_tag="SPC15A_0008"
                     /note="Signal peptide predicted for SPC0680 by SignalP 2.0
                     HMM (Signal peptide probability 0.902) with cleavage site
                     probability 0.355 between residues 31 and 32"
     misc_feature    5578..6159
                     /gene="wchA"
                     /locus_tag="SPC15A_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 1e-158"
     gene            6166..6615
                     /gene="wchJ"
                     /locus_tag="SPC15A_0009"
     CDS             6166..6615
                     /gene="wchJ"
                     /locus_tag="SPC15A_0009"
                     /note="member of homology group 26"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33341.1"
                     /db_xref="GOA:Q4K1K4"
                     /db_xref="InterPro:IPR013969"
                     /db_xref="UniProtKB/TrEMBL:Q4K1K4"
                     /translation="MKICLVGSSGGHLTHLYLLKPFWKDKERFWVTFDKADARSVLSE
                     EVVYPCYYPTNRNIKNLIKNTFLAYKILKKERPDLIISSGAAIAVPFFYIGKLFGSKT
                     VYIEVFDRIDASTLTGKLVYPVTDRFIVQWEEMKKVYPKAINLGGIF"
     gene            6615..7121
                     /gene="wchK"
                     /locus_tag="SPC15A_0010"
     CDS             6615..7121
                     /gene="wchK"
                     /locus_tag="SPC15A_0010"
                     /note="member of homology group 27"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33342.1"
                     /db_xref="GOA:Q4K1K3"
                     /db_xref="InterPro:IPR007235"
                     /db_xref="UniProtKB/TrEMBL:Q4K1K3"
                     /translation="MIFVTVGTHEQQFNRLIKEVDRLKGEGFIQDDVFIQTGYSNYVP
                     KFCKWEKLISYEKMNQFIEEADTIITHGGPATFMAVIAKGKSPIIVPRLKKFGEHVND
                     HQLEFVEKVLNVYNLTVITNISDLNSYISNFDERKKSDLKSKNNLFMEKFIDMINQLM
                     ETGDIKYD"
     misc_feature    6615..7091
                     /gene="wchK"
                     /locus_tag="SPC15A_0010"
                     /note="HMMPfam hit to PF04101, Glycosyltransferase family,
                     score 6.9e-48"
     gene            7114..8313
                     /gene="wzy"
                     /locus_tag="SPC15A_0011"
     CDS             7114..8313
                     /gene="wzy"
                     /locus_tag="SPC15A_0011"
                     /note="member of homology group 150"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33343.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K1Q7"
                     /translation="MTKYINSCIKLLFIYSLFSELLYSYYSVSLLFTIPDLLLLAAAV
                     IVFVDSYSAGKIRVKNPHISLMLFFILLIFLLISFTWGTLNIYGFVMRGRYILGAFLV
                     YFMTNSYLDDRTFSSLINIAYFMQILNLLLVLHQNIVLHLHPDFTNGIFGFTNYANGI
                     QGFYCLALSVLSTVYYLYGKWGTMKSLILIAISCIICALAEIKIFFVIFIFSIILIFI
                     FQKSETVKKIRIISTAAGISLLFLIAYKLIEIVLPDNLYTFFNVTKALSYENRTEFAG
                     RTNTISFLWDNLFYHDYISAIFGKGLGSYSVNYIYELGKMLADGGFISVILLYSFLLS
                     LFIRGTITRGKNKQSERLIVSIIAFVVMISIIVWNSTFTRSTYLVFFFLAIGNAAYKS
                     TKLIRRD"
     gene            8315..9343
                     /gene="wchL"
                     /locus_tag="SPC15A_0012"
     CDS             8315..9343
                     /gene="wchL"
                     /locus_tag="SPC15A_0012"
                     /note="member of homology group 76"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33344.1"
                     /db_xref="GOA:Q4K1K1"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K1K1"
                     /translation="MEIQISVVIPVYNAENTINNCIESALKQDLESFEVILVNDGSND
                     STSRILEQYSDNPQVKIFHQVNMGVSAARNLGLSHASGEYVFFLDSDDILDDGMLSKM
                     YQFVKNNKVDLLSCWHKEPATTQYGGNENKSTSFIARTREEIGAHFVDIFPRSACAKL
                     FFRKIIEENNITFSTEMSLGEDMSFVYQYLMVSKSIGVIDGVYYNIQNVNPQSLSKRY
                     VQNIENSLMIQNQLWNQLLEVYPKIEENYYKQHMDFRFYLANLYVNNLFKFDSPYSSK
                     EKLDQIAQQLKKYRLFLDEKVSKEKMPKNINEMIVFYLLKLKIPVLIYSFYSFKEWWK
                     RRKIKNEG"
     misc_feature    8330..8797
                     /gene="wchL"
                     /locus_tag="SPC15A_0012"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 2.6e-45"
     gene            9351..10307
                     /gene="wchM"
                     /locus_tag="SPC15A_0013"
     CDS             9351..10307
                     /gene="wchM"
                     /locus_tag="SPC15A_0013"
                     /note="member of homology group 77"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33345.1"
                     /db_xref="GOA:Q4K1Q5"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K1Q5"
                     /translation="MEDLISIVVPVYNVEKYLKKSIESVLNQTYQNIEILLVDDGSTD
                     SSGKICESFSKVDPRIRVFHKENGGLSDARNFGIEQMKGQYVAFIDSDDYISKDYVWK
                     LYSSIKNNDSEVSICSFLLVDEKGEKIKDELLDSGKICLTGQQILEKVLTADGYRYVV
                     AWNKLYRSTLFEKLKFKKGMLYEDEFLNYLLFWDCKRVSIVEEPLYLYVQRKGSIVQS
                     NMTLEKIKMKDEMHTSRIEFYSEKGHSFLHEKACQQYCNWIVTATTNHSKILNPNFSK
                     YLQRQFRKFAKYTRNNDIRLIVQNILGFIDIRLAAYVKSKVM"
     misc_feature    9366..9875
                     /gene="wchM"
                     /locus_tag="SPC15A_0013"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 8.3e-51"
     gene            10323..11231
                     /gene="wchN"
                     /locus_tag="SPC15A_0014"
     CDS             10323..11231
                     /gene="wchN"
                     /locus_tag="SPC15A_0014"
                     /note="member of homology group 34"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33346.1"
                     /db_xref="GOA:Q4K1J9"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4K1J9"
                     /translation="MIEKILDSIKNHSFYSKLKDKIHRIIPLYIIKNQNIAFQQDTDI
                     AYRKLKKKFRHISLTGDELKYKMEFSNKVWICWFQGEEHAPELIKTCIQSMRNQLQGR
                     EIIVLTEKNISDYTEIPGYIIEKYKKGWISRAHYSDILRIDLLCRHGGLWVDATVLNT
                     GGDFSNLEVPLFVYKSLNLSRKDSQAIVASSWLISSYSNHPILLYTRKLLWAYWRRKN
                     SLCNYFLFHICFTIATERYPIEWSAVPTFNNHSPHILHFELNEQFSEKRWEQLKHISA
                     FHKLNHHIDYSSGVNTFYKFIVSSKV"
     misc_feature    10395..11228
                     /gene="wchN"
                     /locus_tag="SPC15A_0014"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 4.7e-126"
     gene            11236..12699
                     /gene="wzx"
                     /locus_tag="SPC15A_0015"
     CDS             11236..12699
                     /gene="wzx"
                     /locus_tag="SPC15A_0015"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI33347.1"
                     /db_xref="GOA:Q4K1J8"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K1J8"
                     /translation="MSNKISKNLAYNMGYQLIGIAAPLITSPYLSRILGAENLGIHSF
                     TMSVALYFMMFMLLGIANYGNRTIATVKREGKDILSKTFWSIYSIQLIMSILVTIAYL
                     AYLYLGAVHYKVIAILQLFLLLSNAVDITWFFYGLENFKQIVFRNTLVKLLGLFLIFL
                     CVRQGTDLWKYTFINGSVTLVGQLLLWGQLKGILTWKKIQLKELLPHIKPILILFIPV
                     LAISIFTNMDKYMLGLMVDVKQVGFYDNAGRIIEIPKALIAALGAVMLPRTSYLLAEG
                     QKEKSKYYIEVTILYVMIISSVLMFGLISVSDIFSIIFWGEEFLESGRLISAMSPAFV
                     FSVLGNIIRTQYLIPRAKDKDYVVSLIAGAVVNLVLNYFFIKPFGAMGATVSTVLAEF
                     VLSGMQFWSVRRDLDLKRYLKNGLIFYLFGLIMYLVIITLKTQLPYNIMSLILLIVLG
                     GIVYVIFCCCYILMSRNLHFKLLKEKIIRKVVHKNTL"
     misc_feature    11248..12054
                     /gene="wzx"
                     /locus_tag="SPC15A_0015"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.1e-75"
     gene            13057..13888
                     /gene="wciZ"
                     /locus_tag="SPC15A_0016"
                     /pseudo
     CDS             join(13057..13296,13296..13352,13343..13888)
                     /gene="wciZ"
                     /locus_tag="SPC15A_0016"
                     /note="member of homology group 88"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase (pseudogene)"
     gene            13893..15041
                     /gene="wchX"
                     /locus_tag="SPC15A_0017"
     CDS             13893..15041
                     /gene="wchX"
                     /locus_tag="SPC15A_0017"
                     /note="member of homology group 53"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol phosphotransferase"
                     /protein_id="CAI33349.1"
                     /db_xref="GOA:Q4K1Q2"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="UniProtKB/TrEMBL:Q4K1Q2"
                     /translation="MVVLQNVKFLVRVVFMVIISIVLWPVRIKKNKILFINFNGKGYG
                     DNPKSICEYLRVTYPELDLVWLAKDNEDFPDGVRVVRYKSLQSFYEQASSKVWVYNVR
                     NFERLLKKRGQFYIQTWHGASSFKLIEKQADLPLKYILEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKELSIDSDDYVILYAPTFRD
                     DGDASYLDINFERLLQSIEQEIKKKCKILIRLHPNDSHFSNNISFNHDIIDVTLFSDM
                     QELILLADVLLTDYSSAIFDFMLLNKPYVRYVNDLEKYAELRGLSDTYYELPDPIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     misc_feature    14481..15032
                     /gene="wchX"
                     /locus_tag="SPC15A_0017"
                     /note="HMMPfam hit to PF04464,
                     CDP-Glycerol:Poly(glycerophosphate) gl, score 6.4e-68"
     gene            15077..16105
                     /gene="gtp1"
                     /locus_tag="SPC15A_0018"
     CDS             15077..16105
                     /gene="gtp1"
                     /locus_tag="SPC15A_0018"
                     /note="member of homology group 40"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol-2-phosphate dehydrogenase"
                     /protein_id="CAI33350.1"
                     /db_xref="GOA:Q4K1Q1"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="InterPro:IPR016205"
                     /db_xref="UniProtKB/TrEMBL:Q4K1Q1"
                     /translation="MKNNDLKIGSGAIHQISATLSQNNISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDAVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     misc_feature    15098..16018
                     /gene="gtp1"
                     /locus_tag="SPC15A_0018"
                     /note="HMMPfam hit to PF01761, 3-dehydroquinate synthase,
                     score 2.2e-70"
     gene            16121..16825
                     /gene="gtp2"
                     /locus_tag="SPC15A_0019"
     CDS             16121..16825
                     /gene="gtp2"
                     /locus_tag="SPC15A_0019"
                     /note="member of homology group 41"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotidyl transferase"
                     /protein_id="CAI33351.1"
                     /db_xref="GOA:Q4K1J4"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="UniProtKB/TrEMBL:Q4K1J4"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGTYIEESMKVVEKNGRLVEISKQISPEEAL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILPEVEFIACPLDGRWL
                     EIDNHEDLAVAEKLFA"
     misc_feature    16124..16813
                     /gene="gtp2"
                     /locus_tag="SPC15A_0019"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 8.9e-08"
     gene            16840..17673
                     /gene="gtp3"
                     /locus_tag="SPC15A_0020"
     CDS             16840..17673
                     /gene="gtp3"
                     /locus_tag="SPC15A_0020"
                     /note="member of homology group 42"
                     /codon_start=1
                     /transl_table=11
                     /product="putative phosphotransferase"
                     /protein_id="CAI33352.1"
                     /db_xref="GOA:Q4K1N0"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006357"
                     /db_xref="UniProtKB/TrEMBL:Q4K1N0"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQGSIKPTYTFKNVKEMWKGI
                     V"
     misc_feature    16897..17583
                     /gene="gtp3"
                     /locus_tag="SPC15A_0020"
                     /note="HMMPfam hit to PF00702, haloacid dehalogenase-like
                     hydrolase, score 5.9e-25"
     gene            complement(17762..18151)
                     /gene="tnp"
                     /locus_tag="SPC15A_0021"
                     /pseudo
     CDS             complement(17762..18151)
                     /gene="tnp"
                     /locus_tag="SPC15A_0021"
                     /note="member of homology group 19"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase (fragment)"
                     /db_xref="PSEUDO:CAI33353.1"
     misc_feature    complement(17771..18151)
                     /gene="tnp"
                     /locus_tag="SPC15A_0021"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 0.00012"
                     /pseudo
     gene            18116..18268
                     /gene="tnp"
                     /locus_tag="SPC15A_0022"
                     /pseudo
     CDS             18116..18268
                     /gene="tnp"
                     /locus_tag="SPC15A_0022"
                     /note="Lone member of homology group 0231"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase (fragment)"
     gene            18470..>18517
                     /gene="aliA"
                     /locus_tag="SPC15A_0023"
     CDS             18470..>18517
                     /gene="aliA"
                     /locus_tag="SPC15A_0023"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33355.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ89"
                     /translation="MMKSSKLLALAGVTLL"
BASE COUNT     6119 a   2573 c   3615 g   6210 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acactgcggc taaagaagta cttgaaaaac aggtcttggc tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcata taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attctcgaaa ttcaattaac tttacaaatt cccactattt aaggagaaag aagatgaaca
      301 taaagaagcg agtccttagt gcaggcctga cttttgcatc tgctttgctt ttagctgctt
      361 gcggccaatc aggttcagat acaaaaactt actcatcaac ctttggtgga aatccaacta
      421 catttaacta tctattagac tattacgctg ataacatagt caattgaaac aagaacaaga
      481 caaaagagcc tcataaaagg tatggcaact tggtaatacc ttttacgagg ctttttgata
      541 tgagcccatg ttttctcaat aggattgtac tcaggtgagt agggaggaag aggtaaaagt
      601 ttatacccaa actcttcaca caagagttct aacttaccca ttctatggaa tcttgcatta
      661 tccataataa taaccgatgg tgtggttaat gttggtaaga gaaacttctg aaaccaagct
      721 tcaaaaaagt cgctcgtcat cgtctcttcg taagtcattg gagcgattaa ctcaccattt
      781 gttagacctg caaccaaaga aatcctctga tatcttcttc cagatacttt acctcttatt
      841 aactgacctt ttaatgagcg accatattct cgataaaaat aagtatcgaa tcctgtttcg
      901 tcaatctaaa caggtgctag gtgctttaaa ctattaaaat tcttaagaaa taaggctact
      961 ttttctgggt cttgttcata attagattga aactagaata gtacacctct gcttctaaaa
     1021 cattgttaga aatcgatttg actgtcctga tcgatttgtc atgttcttat ttcattttac
     1081 tatatttttg tttcgcggga agtctactaa gatacttaaa gatgcagata gtaaaaaaaa
     1141 tgtagacatt accgtaaaaa agtgatataa tcgtatgatg ttcaaggtat aggtgttaat
     1201 catgagtaga cgttttaaaa aatcacgttc acagaaagtg aagcgaagtg ttaatatcgt
     1261 tttgctgact atttatttat tgttagtttg ttttttattg ttcttaatct ttaagtacga
     1321 tatccttgct tttagatatc ttaacctagt ggtaactgcg ttagtcctac tagttgcctt
     1381 ggtagggcta ctcttgatta tctataaaaa agctgaaaag tttactattt ttctgttggt
     1441 gttctctatc cttgtcagct ctgtgtcgct ctttgcagta cagcagtttg ttggactgac
     1501 caatcgttta aatgcgactt ctaattactc agaatattca atcagtgtcg ctgttttagc
     1561 agatagtgat atcgaaaatg ttacgcaact gacgagtgtg acagcaccga ctgggactga
     1621 taatgaaaat attcaaaaac tactagctga tattaagtca agtcagaata ccgatttgac
     1681 ggtcgaccag agttcgtctt acttggcagc ttacaagagt ttgattgcag gggagactaa
     1741 ggccattgtc ttaaatagtg tctttgaaaa tatcatcgag tcagagtatc cagactacgc
     1801 atcgaagata aaaaagattt ataccaaggg attcactaaa aaagtagaag ctcctaagac
     1861 gtctaagaat cagtctttca atatctatgt tagtggaatt gacacctatg gtcctattag
     1921 ttcggtgtcg cgatcagatg tcaatatcct gatgactgtc aatcgagata ccaagaaaat
     1981 cctcttgacc acaacgccac gtgatgccta tgtaccaatc gcagatggtg gaaataatca
     2041 aaaagataaa ttaacccatg cgggcattta tggagttgat tcgtccattc acaccttaga
     2101 aaatctctat ggagtggata tcaattacta tgtgcgattg aacttcactt ctttcttgaa
     2161 aatgattgac ttattgggag gggtagatgt tcataatgat caagagtttt cagctctaca
     2221 tgggaagttc catttcccag tagggaatgt ccatctagac tctgagcagg ctctaggttt
     2281 tgtacgtgaa cgctactcac tagccgatgg agaccgtgac cgtggtcgca accaacaaaa
     2341 ggtcattgta gcaattattc agaagttaac ttctacagag gttttgaaaa actatagtag
     2401 tattcttcaa ggattgcagg attctcttca aacaaatatg ccgattgaga ctatgataga
     2461 tttagtgaat actcagttgg aaagtggggg gaattataaa gtaaattctc aagatttaaa
     2521 agggacaggt cggatggatc ttccttctta tgcaatacca gacagtaacc tctatgtgat
     2581 ggaaatagat gatagtagtt tagctgtagt taaagcagct atagaggatg tgatggaggg
     2641 tagatgaaat gatagacgtc cattcgcata tcgtttttga tgtagatgac ggtcccaagt
     2701 caagagagga aagcaaggct ctcttggcag aatcctacag gcagggggtg cgaaccattg
     2761 tctctacctc tcaccgtcgc aagggcatgt ttgaaactcc ggaagagaag atagcagaaa
     2821 actttcttca ggttcgggaa atagctaagg aagtggcgag tgacttggtc attgcttacg
     2881 gggctgaaat ttactacaca ccagatgttc tggataagct agaaaaaaag cggattccga
     2941 ccctcaatga tagtcgttat gccttgatag agtttagtat gaacactcct tatcgcgata
     3001 ttcatagcgc cttgagcaag atcttgatgt tgggaattac tccagtcatt gcccacattg
     3061 agcgctatga tgctcttgaa aataatgaaa aacgcgttcg agaattgatc gatatgggct
     3121 gttacacgca agtaaatagt tcacatgtcc tcaaatccaa actttttggc gaacgttata
     3181 aattcatgaa aaaaagagct cagtattttt tagagcagga tttggtccat gtcattgcaa
     3241 gtgatatgca caatctagac ggcagacctc ctcatatggc agaagcatat gaccttgtta
     3301 cccaaaaata cggagaagcg aaggctcagg aactttttgt agataatccc agaaaaatta
     3361 taatggatca attaatttag gagaaaatat ggaggaacaa aacactttgg aaatcgatgt
     3421 attgcaacta ttcagatctt tgtggaaaag aaagttggtc attttattag tggcaattat
     3481 aacttcttca gttgcttttg cctacagtac ttttgttatc aaacctgagt ttactagtac
     3541 gactcggatt tatgtagtta accgtgatca gggagagaag tctggtttaa ccaatcaaga
     3601 cttgcaggca ggaacatact tggttaaaga ctatcgtgaa attatcctat cgcaggatgt
     3661 tttggaggaa gttgtttctg atttgaaact agatttgacg ccaaaaggtt tggctaataa
     3721 aattaaagtg acagtaccag ttgatacccg tattgtctca atctctgtca aggataaaca
     3781 gccagaggaa gccagtcgta tcgctaattc tctacgagaa gttgctgcag aaaagatcgt
     3841 cgctgtaacg cgagtatctg atgtaacgac acttgaagaa gcgcgaccag ctacgactcc
     3901 ctcttctcca aatgttcgac gcaacacctt gtttggtttt cttggaggag ccgtcgtaac
     3961 agtaattgct gttcttttga ttgagttgct cgacacccgt gtgaaacgtc ctgaagatgt
     4021 tgaagatgta ctgcaaattc cacttttagg gctcgttcca gatttggaca aaatgaaata
     4081 ggaggaagtt atgccaacgt tagaaatctc acaggcaaaa ttggattttg taaaaaaggc
     4141 agaggaatat tataacgctt tgtgcacgaa cctacagtta agtggagatg gtttgaaagt
     4201 attttctatc acttctgtga aactaggaga aggaaaatca acgacttcca ccaatatcgc
     4261 ttgggctttt gcgcgtgcag gttacaaaac gctgctgatt gatggagata ttcgcaattc
     4321 tgttatgtta ggtgtcttta aagcaaggga taagattaca ggcctgacag aatttttatc
     4381 aggaactaca gacctatcac aagggctttg tgataccaat atcgaaaatc tctttgtaat
     4441 tcaggctggc tctgtgtcac cgaatccgac agctcttctt caaagtaaga atttcagtac
     4501 aatgcttgaa acattgcgta aatattttga ctacatcatt gtagatactg ctcctgtcgg
     4561 tgtcgtgatt gatgcggcta ttattacgcg aaaatgcgat gcttctattt tagtgacgga
     4621 ggcaggtgaa ataaatcgac gggatattca aaaagcaaaa gaacagttgg aacacacagg
     4681 gaagccgttt ttgggagttg tgttgaataa attcgatact tcagtagaca aatacggttc
     4741 ttatggaaat tatggagatt acgggaaaaa taaaaaatag gtcgggggat agagatgaat
     4801 ggaaaaatag taaagtcttc attggccata atccagagtt ttcttgttat tttattgact
     4861 tatctactta gtgctgtgag agaagcggag attgtttcaa caacagctat tgcactttat
     4921 atcctccatt attttgtctt ttatatcagt gattatggac aggatttctt taaaagggga
     4981 tatttgattg aacttgtcca gacattgaaa tatatcctat tctttgcact agcgattagt
     5041 atttctaatt ttttcttaga ggatcgattt agtatttcca gacgaggcat gatttacttc
     5101 ctcacattac atgctctctt agtctatgtg ctaaacctat ttatcaagtg gtattggaag
     5161 cgggcttatc ccaactttaa aggaagtaag aagattctcc tacttacagc aacttctcgt
     5221 gtcgaaaagg tactggatag attaatagaa tcaaatgagg ttgttgggaa gttggtagcc
     5281 gtcagtgtct tagataaacc agattttcag catgattgtt taaaggtagt agcagagggg
     5341 gagatagtaa actttgcgac tcatgaggtg gtcgatgaag tctttatcaa tcttccaagt
     5401 gaaaaataca atattggaga gcttgtctct cagtttgaaa cgatgggaat tgatgtaaca
     5461 gtcaatctaa atgcttttga tcgtagtttg gcacgtaaca agcaaatccg tgagatggca
     5521 ggattaaacg ttgtgacttt ttctacaaca ttttataaga ctagtcatgt aattgctaag
     5581 cggattattg atatcgtggg tgcattggta gggctgatac tatgtggtct agccagtatt
     5641 gtactggttc ctttgattcg aaaggatggg ggctctacta tttttgctca gacgcgtata
     5701 ggaaaaaatg gtcgtcagtt cactttttat aagtttcgct ctatgtgtgt agatgccgag
     5761 gcgaaaaaaa gagaactcat ggaacaaaat accatgcagg gtggaatgtt taaggtggac
     5821 gatgatcctc gtatcacgaa aattggtcgt tttatacgga agactagctt ggacgagcta
     5881 ccacagtttt ataatgttct aaagggagat atgagtttgg ttggcacacg gccaccaaca
     5941 gtggacgagt atgaacacta taccccagaa caaaaacgtc ggctaagttt taaacctggt
     6001 ataacaggct tatggcaggt cagtggacga agtgagatta agaattttga tgaagttgtc
     6061 aaattagatg tagcctatat agacgattgg acaatttgga aagacattga aattttattg
     6121 aagacagtta aagttgtatt tatgagagac ggagcgaagt aggaaatgaa aatatgttta
     6181 gttggatcta gtggaggtca tctgactcat ttatatcttt taaaaccttt ctggaaagat
     6241 aaagaaagat tttgggttac ttttgataag gcggacgctc ggagtgtact ctctgaggaa
     6301 gttgtatatc cctgttatta tccaaccaat cgtaatataa aaaatttaat aaaaaatact
     6361 tttctcgcct ataaaatttt aaaaaaagag agaccagatt tgattatttc ttctggtgcc
     6421 gctatcgctg ttcctttctt ttatattggg aagttatttg gatcaaagac agtgtatata
     6481 gaagtttttg atagaattga tgcttcaaca ctgacaggaa aacttgttta tccagtaacg
     6541 gataggttta ttgttcaatg ggaagaaatg aaaaaagtat acccaaaggc aattaatctc
     6601 ggagggattt tctaatgatt tttgtgacag taggtactca tgaacaacag tttaatcgac
     6661 ttattaaaga ggttgataga ttaaaaggtg agggatttat tcaggatgat gtttttattc
     6721 aaacaggata ctctaattat gttccaaaat tttgtaaatg ggaaaaatta atatcttatg
     6781 aaaaaatgaa tcaatttatt gaggaagctg atacaatcat tacccatggc ggtccagcta
     6841 cgtttatggc agttattgct aaagggaaaa gtccgataat tgttccgaga ttaaaaaaat
     6901 ttggtgagca tgtgaacgac catcaacttg aatttgttga gaaagtgtta aatgtctata
     6961 atttgacagt catcactaac ataagtgatc ttaattccta tatttctaat tttgatgagc
     7021 gaaaaaaatc agatttgaag agcaaaaata atctatttat ggagaaattt atagatatga
     7081 ttaatcagtt gatggagaca ggtgacatca agtatgacta agtacataaa tagctgtatc
     7141 aagttgttat tcatatattc gttatttagt gaattgctat actcatatta ttctgtatct
     7201 ctattattta cgatacctga cttattattg ttggcagcag cagtaattgt ttttgtagat
     7261 tcttattctg cagggaaaat aagagttaaa aatcctcaca ttagtttaat gctctttttt
     7321 atattgctga tatttctatt aattagtttt acttggggta ctcttaatat atatggattt
     7381 gttatgagag gaagatatat actgggagca tttctagttt attttatgac aaatagctat
     7441 ctagatgata gaaccttttc atcattgata aacattgctt attttatgca gatattgaac
     7501 ctattattag ttttacatca aaatatagta ttacatttgc accctgactt cactaatggg
     7561 atttttggtt ttactaatta tgcaaatgga atccaaggat tttattgctt agccttaagt
     7621 gttttatcta ctgtatatta tctgtatggt aaatggggaa caatgaagtc attaatattg
     7681 attgctattt cgtgtataat ttgtgcatta gcagaaataa agattttttt tgtcattttt
     7741 atattttcta ttattctaat ttttatattt caaaagtcag aaacagtaaa aaaaatacga
     7801 ataattagta cagctgctgg aatatctctt ctttttttaa ttgcctataa actcattgag
     7861 atagttttac ctgataattt gtatactttt tttaatgtta caaaggcatt atcatatgag
     7921 aataggacag agtttgcggg acgaacaaat actatttcct tcctatggga caacttattt
     7981 tatcatgatt atattagtgc tatatttggg aaaggactag gttcatactc tgttaattat
     8041 atttatgaac ttggtaaaat gcttgcagat ggtggtttta tttcagtgat tttgctttat
     8101 tcatttttgt tgtcattatt catacgggga actattacta gaggaaaaaa taagcaaagt
     8161 gaaagactaa ttgtatccat catagctttt gtggtgatga ttagcattat tgtttggaat
     8221 agtacgttca ctagatcaac ttatcttgta tttttctttc tagcaatagg taatgcagcg
     8281 tataagtcta ctaaattaat aagaagggat tgagatggaa attcaaatat cagtggtgat
     8341 tccagtatac aatgctgaaa acacgattaa taattgtatt gaaagtgctt taaaacaaga
     8401 tttagaatct tttgaagtaa ttttagtaaa cgatggatcg aacgattcta catcaagaat
     8461 tcttgaacag tatagtgata atccccaagt gaagatattt catcaagtga acatgggagt
     8521 atctgctgcc agaaatttag gtttatctca tgcaagcgga gaatacgtat tctttttaga
     8581 ttcagatgat attttagatg atggtatgct ttctaaaatg taccaatttg taaaaaataa
     8641 taaagttgat ctcttatctt gttggcataa agaacctgct acaactcaat acggtggaaa
     8701 tgagaataag tcaacttcat ttattgcacg tacaagagaa gaaataggtg ctcattttgt
     8761 tgatatcttt ccgagaagtg cttgtgccaa attgtttttt cgcaaaataa ttgaagaaaa
     8821 taatattact ttttcgactg agatgtcact aggtgaagat atgtcatttg tgtatcaata
     8881 cttaatggtt tctaaaagta ttggagttat tgacggggtg tattataata ttcaaaatgt
     8941 aaatccacag tcgttatcta agcgctatgt gcagaatatt gaaaattccc taatgattca
     9001 gaaccagtta tggaatcaac tgttggaagt ttatcctaaa attgaggaga actactataa
     9061 gcaacatatg gattttagat tttaccttgc taacttgtat gtaaataatt tatttaaatt
     9121 tgattctccg tattcatcaa aagaaaaact agaccaaatt gctcaacaat taaaaaagta
     9181 tagattattt ttagatgaaa aagtcagcaa agaaaagatg cctaaaaata taaatgagat
     9241 gattgttttt tatttactaa aattgaaaat tccagtgttg atttattctt tttattcgtt
     9301 taaagagtgg tggaagagaa gaaaaattaa aaatgaagga taaataagtt atggaagatt
     9361 tgataagcat tgttgttcca gtctataacg tggaaaaata tttaaaaaaa tcaatagaaa
     9421 gtgttttgaa tcagacttat caaaatatcg agattttatt ggttgatgac ggaagcacag
     9481 atagtagtgg gaaaatttgt gaatcattta gcaaagttga tcctaggata agagtatttc
     9541 ataaagaaaa tggtggttta tcagatgctc ggaattttgg aattgagcaa atgaaaggtc
     9601 aatatgtagc gtttattgat agcgatgact acatatctaa ggattatgtc tggaagttgt
     9661 attcttctat aaaaaataat gattccgagg tgtcgatttg ttctttttta ttagtcgatg
     9721 aaaaagggga aaaaataaaa gatgagctat tagattcggg aaaaatatgc ttgactggtc
     9781 aacaaatatt agaaaaagta ttaacagccg acggctatcg ctatgttgtt gcttggaata
     9841 agctttatcg gtcaacttta tttgaaaaat taaaatttaa aaaaggaatg ttgtatgagg
     9901 atgaatttct taactatctt ctattttggg actgtaaaag ggtatcaatt gtagaggagc
     9961 cgttatattt atacgttcaa cgaaaaggaa gcattgtaca aagtaatatg actttagaaa
    10021 aaataaagat gaaggatgag atgcatactt cacgcattga gttttattca gaaaaggggc
    10081 attctttttt gcacgaaaaa gcgtgtcaac agtactgcaa ttggattgtt acagcgacta
    10141 ccaatcatag taagatttta aatcctaatt tttcgaagta tttacaacga cagtttagaa
    10201 agttcgctaa atatacacga aacaatgata ttagactaat tgtgcagaac attctaggat
    10261 ttatagatat tcgtttagca gcttatgtaa aatcaaaagt aatgtagagt ataggaaaca
    10321 taatgataga aaaaatttta gattctatta aaaatcattc tttttatagt aaattgaagg
    10381 ataaaattca tagaattatt ccattatata ttataaaaaa tcaaaatata gcttttcaac
    10441 aagataccga tatagcatat agaaaactaa agaagaagtt taggcatatt tcgttgactg
    10501 gagatgagct taaatataaa atggagtttt caaataaagt ttggatttgt tggtttcagg
    10561 gagaagagca tgccccagag ttaattaaaa catgtattca atcaatgagg aatcaacttc
    10621 aaggaagaga aatcattgtg ttgacagaaa aaaatataag tgattataca gagattccag
    10681 gctatattat tgaaaaatac aaaaaaggat ggatttctcg tgcgcattac tctgatatcc
    10741 ttaggataga tcttctatgt cgccatggag gattatgggt agatgcaaca gtgttgaata
    10801 caggaggaga tttctcaaat cttgaggtac cactttttgt atataaatct ttgaatttat
    10861 caagaaaaga ttcacaagct attgtagcat caagttggtt aatttcgtca tatagtaatc
    10921 atcctatatt actctatacg agaaaactcc tatgggccta ctggcgaaga aaaaatagtt
    10981 tatgtaatta ttttttgttc catatatgtt ttacaatagc tacagagcgg tacccaatcg
    11041 aatggtctgc tgtccctact tttaataatc attctcctca tatacttcat tttgagttga
    11101 atgaacaatt ttcggaaaaa cggtgggaac aactgaagca tatttcggcg tttcataaat
    11161 taaatcatca tatagattat tctagcggtg ttaacacttt ttataagttc atagtatctt
    11221 cgaaagttta gaaaaatgag taataaaatt agtaaaaatt tagcctacaa tatggggtat
    11281 cagttaattg ggattgcagc tcccttgata acttctcctt atttatcacg gatattaggt
    11341 gctgaaaatt taggtattca ttcttttact atgtcggttg cactttactt tatgatgttt
    11401 atgcttcttg gaattgcaaa ttacggaaat agaacaattg cgactgttaa acgagaagga
    11461 aaggatattc tatcaaaaac gttttggagt atctactcta tccagttgat aatgtctatt
    11521 ctggtaacta tagcttatct tgcttatcta tatttggggg cagtacatta caaagttatt
    11581 gcaatattac aactcttttt attgttatca aatgctgttg atattacttg gtttttctat
    11641 ggattagaaa attttaagca aatcgttttt aggaatacat tagtcaaact tttaggatta
    11701 tttttaattt ttttatgtgt gcgtcaaggc acagatttat ggaaatacac atttataaac
    11761 ggatcagtaa ctttagttgg ccaactttta ctatggggac aattaaaagg aatattaact
    11821 tggaaaaaaa ttcaattaaa ggaattacta cctcatatca agccaatttt aattcttttt
    11881 attcctgtac tagccattag tatttttact aatatggata aatatatgct tggtttaatg
    11941 gttgatgtaa agcaggttgg attttatgac aatgcaggta gaattattga aattcctaaa
    12001 gctttgattg cagctttagg ggccgttatg ttaccaagaa cttcctattt attagcggaa
    12061 ggacagaaag aaaagagtaa atactacata gaggtaacaa ttttatacgt gatgattatt
    12121 tctagtgtat tgatgtttgg gctaatatcg gtatctgata ttttttccat tatattttgg
    12181 ggagaagaat ttcttgaatc aggtagattg atttctgcta tgtctccggc ttttgtcttc
    12241 tctgtattag gaaatatcat taggactcag tatttgattc ctagagctaa ggataaagat
    12301 tatgtagtgt ctctaattgc gggggctgtt gttaatctag tgctaaacta tttttttata
    12361 aaaccttttg gtgctatggg agcaacagtt agtacagttt tggcagaatt tgtattgtct
    12421 ggaatgcagt tttggtcagt aagaagagac ttagatttaa aaagatattt gaaaaacggt
    12481 ttgatattct acctatttgg tctgattatg taccttgtta ttataacact caaaactcag
    12541 ttaccataca atataatgag tcttatttta ctaatagttt tgggtggaat agtatatgtt
    12601 attttttgtt gttgctatat tttaatgtca agaaatttac attttaagtt attgaaggaa
    12661 aagattatac gaaaggttgt acataaaaat acattataaa atattagttt tattttattt
    12721 agttggatac tattaaataa acgaaagtat ttgaaacttt ggtaattgag attatagaga
    12781 taaactaagc tatattatag cttcattatt aaagtaagaa tatcggtgca gtgtagttaa
    12841 cgaataatgt gagtactcat ttcttagatg gagctagggg tcattataag ggattgatat
    12901 gacattttga gtaagttaca gctagagttt aggtttgatt atatcagata tttagatgat
    12961 ttggaaaata ataaaataag ttaggaacta tttttttatt gttttgagtg acaggtttga
    13021 ttttgggaaa tgtattttgt taaataggta ggaaagatgg ttactaaaga taaaggatta
    13081 acatataata gtactttgca tgcaataaaa gtattagcat gttttagtgt tgttgctatt
    13141 catatatggc taccaggaaa aattggagcg ttttatcaaa taatagcacg atttgcagtt
    13201 ccaatgttct ttttgatttc tggcttttat tcatataata tttcaaagaa tagaattaaa
    13261 aaaatattta gattgatatt aagaagtaca ttttttatgt aataatattt gtatggatgt
    13321 tttggagaga aggtaatatg cagtttattt ttccaataaa agactactat tgacaaaacg
    13381 atggatttct atgcttttac tattttcttt cattatggaa gctacaatta gcgattcaat
    13441 tttttataga aattttttat ttatgggaat accatttttt ggaataggaa ttcttattgc
    13501 acagaatcaa aagaagatta ttaattgtaa aataataaac aaaatattaa tcttgggaac
    13561 aattatctat ccaatactaa tatttttaga atattatatc ttgggtaatt cttttgaggt
    13621 ctatataagt tctgtgctag caaccataat attgatgatt ttcgcgatta aatcacctaa
    13681 agcgattaat atcaaaatac tgaatggaat tggagataaa tatgcgactt ttgtttacat
    13741 tatacaccag tttatcattg tgatatttaa atttttagta tctaatgttt atattctcaa
    13801 atttgggacg atatttgtct ttttgatatg ttgttttcta ggggttctat ttcaatttat
    13861 caaaaacaga ctattaaaaa ggtttagtta agatggttgt tttacaaaat gttaaatttt
    13921 tagtaagagt tgtttttatg gttattatca gtatagtgtt atggcctgtt cggataaaga
    13981 agaataagat actatttatt aattttaatg gtaagggata tggtgataat ccgaaaagta
    14041 tttgtgagta tcttcgagtt acatatccag agttagattt agtttggctt gcaaaagata
    14101 atgaagattt tccagatgga gtgagagttg taagatataa atctctacaa tctttttatg
    14161 agcaagctag ttcgaaggtt tgggtttata atgtaagaaa ttttgaaaga ctactaaaaa
    14221 aacgcggaca gttttatatt caaacttggc acggtgcttc tagttttaaa ctgatagaaa
    14281 agcaggctga tttaccatta aaatatattt tagaagcaaa gtatgatgca agagtcacag
    14341 atataatgat ttcagatagc agaaaacaaa ctgaagaatt tcaaaagtat ttttggtatt
    14401 caggagaaat ttttgaggtg gggatgccga gaaatgatgc cttgtttcac tataaggaag
    14461 actacgacaa gttaaataat atcagaaaag aactaagcat tgattcagat gattatgtta
    14521 ttttatatgc ccctactttc agagatgatg gggatgcatc ttatttagat ataaattttg
    14581 aacggctttt gcaaagtatt gaacaagaaa ttaagaagaa atgtaaaatt ttaattagat
    14641 tacatcctaa tgactctcat tttagtaata atatttcttt taatcatgac ataattgatg
    14701 ttacgctatt ctcagatatg caggaactta tattattggc agatgtttta ctgacagatt
    14761 attcttccgc gatatttgat tttatgcttt taaacaagcc ttatgtcaga tatgtgaatg
    14821 atttagaaaa atatgctgag cttaggggac tatcagatac atattacgaa ttgccggacc
    14881 ctatcattaa aactgctgaa gaattgtatg acttactgcc taaaaaaata gaaaattttg
    14941 attatgattc tataaaaaaa tatagaaatg aaatactgtg tccaatcttt aatggaaccg
    15001 ctagtgaaaa tgtaggaagg agaataattc aagagttgtg aagtaaaaca ttgggttatt
    15061 tttaaggtaa cgagatttga aaaataatga tttaaagata ggaagtggag ctattcatca
    15121 aatctccgct acactttctc aaaataatat ttcgggaaag attttatatt gtgctgatcc
    15181 agttgtcgat gacttgtacg gttcgatagt acgttcacaa atagaggaaa ttggtcgggt
    15241 aaaggaagaa agttgcaatt ataatactat tgcttatgcg atgaatatag cagaaagggc
    15301 tattgccaca gatattgact gtattgtggg aatgggagga ggtcgtgttt tagatgtctg
    15361 caagtatgca tcttttattt cgaaacgtcc ttacctatcg attccgacaa cagcagcaaa
    15421 tgatggcatt gcttccccag ttgctgtttt gaaaaggcag gatgatagac caaaaagctt
    15481 aggggcggct atcccctcaa tgacactaat tgatattgat gttattgcat caggacctat
    15541 acaaaacata aaagctggta tcggtgatac aatatccaat tacactgcat tgaaagattg
    15601 ggagttggca gttgagcgag ggaaagatga gatgcatggt tttgcatatc taatgtcgca
    15661 aaattcttta gatgctttaa tgaaaacgaa gtataattct attacccctg attttattga
    15721 agttttggta aactctttag ttttatcagg cattgcaatg gattttgcgg gaagtagtag
    15781 acctgtcagt gggtcagagc acttatttag tcatgcatta gattactatg gttctacaag
    15841 gaatcttcat ggaattcagg ttgcattagg tacagtcgca gttttgaaat taattgaaaa
    15901 ttctgttgat gctgtggtgg attacttgca aagatttgag gttcatatta acccgaaact
    15961 tttggggata gatgaagagt tgtttattta ttgtatgcaa catgctacaa aaatgagaag
    16021 taatcgctat acttatctgc atgaggttga tcttagtaca gatagattga aacaaatata
    16081 taaggaactc ataagcgagt tgtagaaaag agagaaaaaa atgaaagcac ttattttagc
    16141 agcagggtta ggaacacgtc tagccccaat taccaatgag gtaccaaaat ctttggtacc
    16201 agtcaatggt aagccaattt tgatgaaaca aattgaaaat ttatatcaaa ataatattac
    16261 agatattacg attattgctg gatataagtc atctgtatta acagatgcag ttactgaaaa
    16321 gtatccagaa attaatatta ttgataatgt tgattttaaa acgactaata atatgtattc
    16381 agcctatcta ggaaaagctg caatgggtga tagtgacttc ttaatgatga atgcagatgt
    16441 attttatgat gcttctgtta ttaaaagtct gttgcttcat aaagctccaa atgcaattgt
    16501 aactgattta ggtacttata ttgaagagtc tatgaaagtc gtagaaaaaa atgggcgttt
    16561 agtggaaatt tctaaacaga tttcacctga ggaggcttta ggggcttcta ttgatgttta
    16621 taaattctct tatgaagcag gtgctcgatt ctttgaaaag tgtaaggaat ttattgaaga
    16681 taaacgagaa cttcaaatgt ggagtgaggt tgctcttaat gcaatccttc cagaagttga
    16741 gtttatagca tgtccattgg atggccgttg gttagaaatt gataatcatg aagacctagc
    16801 tgttgcagaa aaactatttg cttaaaccga atatggagaa tgaaattgac aaatagagtt
    16861 gattattttg gtgctgatat tagtgaactt cagaataaaa aattattctt atttgatatg
    16921 gatggtacca tttatgaaga agatagattg tttgagggta ctctcgaatt attagactat
    16981 attcataata ttggcggtga gtatattttt attacaaaca attcatctaa gtctgttgtt
    17041 gactatgttg aaaaagttaa cagattaggt attaaagctg aacgagataa tttttttacc
    17101 tctgctcaag ccacaattgt ttatattaaa gaaaattatc ctaaatctaa agtttattgc
    17161 caaggaacaa aatctttgat aaaagaacta tctgacgcag gaattgatgt aactgagcaa
    17221 gttagtgctg atatagatgt tgttcttgtt ggttttgata cagaattaac cagtgataaa
    17281 attcgcaata cctgcgagat tctatcaaca aaggacgtac ctttcatagc tactaaccct
    17341 gatattcgct gcccagtatc gtttggattc atcccagatt gtggttctat ttgtgatatg
    17401 attagtaaat cagtcgatag gaaacctgtt tacataggta aacctgaacc tacgatggtt
    17461 gatattgttc gaaaaaaatt aaattattct ctatttgaaa cagttgtgat tggagatcgc
    17521 ttgtatacgg atatcatgac tggtataaat gcaggagtaa cttcagtttg tgtgctgaca
    17581 ggagaagcaa cggtgaatga tattcaacaa ggtagtataa aaccgactta tacatttaaa
    17641 aacgtgaaag aaatgtggaa aggaattgtc tgattttttc attctgaata gtgaattcat
    17701 gaatactgtc aaaatactcg tatgtattta aattgatttt attattagac ttcctgcaaa
    17761 actagaatcc tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaagc
    17821 gtttacgatg atttcgataa gttgttgaaa acattttaaa cgtttttact ttggcaaaga
    17881 tgttctcaac cttgcttctc tccgtagata gtgcatggtt acaggcttta tcttcagctg
    17941 ttagcggctt gagttcgctg gatttacgtg gagtttgtgc ttgaggatat atcttcataa
    18001 gcccttgata accactgtca gccaagattt taccagcttg tccgatattt ctgcgactca
    18061 ttttgaacaa cttcatatca tgactatagt tcacagtgat atccaaagaa ataattctcc
    18121 cttgacttgt gacaatcgtc tgagccttca tagcgagaaa tatctattct atcttctaga
    18181 atgtcttcca aacgaggaaa ctctcgtaaa caaagaggtt ttagaggctt atttaccatg
    18241 gactaaagtt gtacaagaaa agtgcaaata agaaatctcc agattaggaa ctatatatga
    18301 gttctctagt ctggagattt ttcaatagac ttcgttattg ggcggttaca atgatattca
    18361 tattttttgc aaagatgttg tttgaaaaat aattttcaaa aattctgaaa attctgttga
    18421 catctttctg aaaagagtct ataatggaga gaaagtttta aaggagaaaa tgatgaaaag
    18481 ttcaaaacta cttgcccttg cgggcgtgac attattg
//
