LOCUS       CR931664               18624 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 7904/39 (serotype 15b).
ACCESSION   CR931664
VERSION     CR931664.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18624)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 18624)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..18624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="7904/39"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC15B_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC15B_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI33356.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..445
                     /gene="aliB"
                     /locus_tag="SPC15B_0002"
                     /pseudo
     CDS             293..445
                     /gene="aliB"
                     /locus_tag="SPC15B_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
                     /db_xref="PSEUDO:CAI33357.1"
     gene            complement(459..981)
                     /gene="tnp"
                     /locus_tag="SPC15B_0003"
                     /pseudo
     CDS             complement(join(459..521,532..981))
                     /gene="tnp"
                     /locus_tag="SPC15B_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            1204..2649
                     /gene="wzg"
                     /locus_tag="SPC15B_0004"
     CDS             1204..2649
                     /gene="wzg"
                     /locus_tag="SPC15B_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33359.1"
                     /db_xref="GOA:Q4K1M7"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K1M7"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1204..1320
                     /gene="wzg"
                     /locus_tag="SPC15B_0004"
                     /note="Signal peptide predicted for SPC0698 by SignalP 2.0
                     HMM (Signal peptide probability 0.997) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1408..1755
                     /gene="wzg"
                     /locus_tag="SPC15B_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 6.7e-65"
     misc_feature    1933..2376
                     /gene="wzg"
                     /locus_tag="SPC15B_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 5.7e-70"
     gene            2651..3382
                     /gene="wzh"
                     /locus_tag="SPC15B_0005"
     CDS             2651..3382
                     /gene="wzh"
                     /locus_tag="SPC15B_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33360.1"
                     /db_xref="GOA:Q4K1P5"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K1P5"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     misc_feature    2654..3262
                     /gene="wzh"
                     /locus_tag="SPC15B_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 4.1e-37"
     gene            3391..4083
                     /gene="wzd"
                     /locus_tag="SPC15B_0006"
     CDS             3391..4083
                     /gene="wzd"
                     /locus_tag="SPC15B_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33361.1"
                     /db_xref="GOA:Q4K1M5"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K1M5"
                     /translation="MKEHNTLEIDILQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGTYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNILIGFLAGGVGTGVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     misc_feature    3409..3825
                     /gene="wzd"
                     /locus_tag="SPC15B_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 9.6e-54"
     misc_feature    3931..4008
                     /gene="wzd"
                     /locus_tag="SPC15B_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4093..4776
                     /gene="wze"
                     /locus_tag="SPC15B_0007"
     CDS             4093..4776
                     /gene="wze"
                     /locus_tag="SPC15B_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33362.1"
                     /db_xref="GOA:Q4K1M4"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K1M4"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVILNKFDVQHKKYGSY
                     GDYGNYGKK"
     gene            4792..6159
                     /gene="wchA"
                     /locus_tag="SPC15B_0008"
     CDS             4792..6159
                     /gene="wchA"
                     /locus_tag="SPC15B_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33363.1"
                     /db_xref="GOA:Q4K1M3"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K1M3"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGHLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLVL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKMDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFI
                     RDGAK"
     misc_feature    5575..6156
                     /gene="wchA"
                     /locus_tag="SPC15B_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 5.1e-145"
     gene            6163..6612
                     /gene="wchJ"
                     /locus_tag="SPC15B_0009"
     CDS             6163..6612
                     /gene="wchJ"
                     /locus_tag="SPC15B_0009"
                     /note="member of homology group 26"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33364.1"
                     /db_xref="GOA:Q4K1M2"
                     /db_xref="InterPro:IPR013969"
                     /db_xref="UniProtKB/TrEMBL:Q4K1M2"
                     /translation="MKVCLVGSSGGHLTHLYLLKPFWNDKERFWVTFDKADARSVLSE
                     EVVYPCYYPTNRNIKNLIKNTFLAYKILKKERPDLIISSGAAIAVPFFYIGKLFGSKT
                     VYIEVFDRIDASTLTGKLVYPVTDRFIVQWEEMKKVYPKAINLGGIF"
     gene            6612..7115
                     /gene="wchK"
                     /locus_tag="SPC15B_0010"
     CDS             6612..7115
                     /gene="wchK"
                     /locus_tag="SPC15B_0010"
                     /note="member of homology group 27"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33365.1"
                     /db_xref="GOA:Q4K1M1"
                     /db_xref="InterPro:IPR007235"
                     /db_xref="UniProtKB/TrEMBL:Q4K1M1"
                     /translation="MIFVTVGTHEQQFDRLIKEVDYLKKENLIQDEVFIQIGYSSYIP
                     KYCEWEKIISYEKMNQLIKESDIIITHGGPATFMGVIAKGKVPIVVPRQKKFGEHVND
                     HQLQFVKLTKEIYNFIVIDDISDLYLSIRDFKDKYFGICLNNERFNLHFNAEINKLFE
                     GNKVDEN"
     misc_feature    6612..7088
                     /gene="wchK"
                     /locus_tag="SPC15B_0010"
                     /note="HMMPfam hit to PF04101, Glycosyltransferase family,
                     score 7e-44"
     gene            7105..8277
                     /gene="wzy"
                     /locus_tag="SPC15B_0011"
     CDS             7105..8277
                     /gene="wzy"
                     /locus_tag="SPC15B_0011"
                     /note="member of homology group 103"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33366.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K1M0"
                     /translation="MKIRIEPQYFLYKYLWLIILLPKQFMQLILFSLIVLILLPVYIK
                     DRQISKIDAPSFYIVLWVMMYSISIIWNFLISGLPIQVLFSDLSKAFNWILAVFFYNY
                     YLKNPINVDKIKKYMFYNFAILVIIVALFYVQRGANVVLFGRSLLGWDGFVSATSYGV
                     RYAGFLEYSTLNGQLILFLLPLIRLFKLSFFTQVTILAFLLQVLVLSKSRIAIIALII
                     YIVFVVMVQITSINKRMIVAFYPTIPLILLYNWEKIKHIFFQMFNSRTGSNVTRFIVY
                     EESLKAINGLGILLGAGIRTQSTVGILLGSHSMYISFIYRTGILGSIIIVILFYYLFS
                     KFLKSAPSGKLISIGYILALLVFWLFEELDPHYWCLILFFSTISIFINNRKEEIVG"
     gene            8274..9299
                     /gene="wchL"
                     /locus_tag="SPC15B_0012"
     CDS             8274..9299
                     /gene="wchL"
                     /locus_tag="SPC15B_0012"
                     /note="member of homology group 76"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33367.1"
                     /db_xref="GOA:Q4K1L9"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K1L9"
                     /translation="MIEVSIIIPIYNAEKTIKNCVDSALKQNLESLEVILVNDGSNDS
                     TAEILNQYDRNSRVKIFHQLNKGVSTARNKGLSHASGEYVFFLDSDDILDDGMLSKMY
                     QFVKNNKVDLLSCWHKEPATTQYGGNENKSTSFIARTREEIGAHFVDIFPRSACAKLF
                     FRKIIEENNITFSTEMSLGEDMSFVYQYLMVSKSIGVIDGVYYNIQNVNPQSLSKRYV
                     QNIENSLIIQNQLWNQLLEVYPKIEENYYKQHMDFRFYLANLYVNNLFKFDSPYSSKE
                     KLDQIAQQLKKYRLFLDEKVSKEKMPKNINEMIVFYLLKLKIPVLIYSFYSFKEWWKR
                     RKIKNEG"
     misc_feature    8286..8753
                     /gene="wchL"
                     /locus_tag="SPC15B_0012"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 9.2e-44"
     gene            9307..10263
                     /gene="wchM"
                     /locus_tag="SPC15B_0013"
     CDS             9307..10263
                     /gene="wchM"
                     /locus_tag="SPC15B_0013"
                     /note="member of homology group 77"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33368.1"
                     /db_xref="GOA:Q4K1L8"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K1L8"
                     /translation="MEDLISIVVPVYNVEKYLKKSIESILNQTYQNIEILLVDDGSTD
                     SSGKICESFSKVDPRIRVFHKENGGLSDARNFGIEQMKGQYVAFIDSDDYISKDYVWK
                     LYSSIKNNDSEVSICSFLLVDEKGEKIKDELLDSGKICLTGQQILEKVLTADGYRYVV
                     AWNKLYRSTLFEKLKFKKGMLYEDEFLNYPLFWDCKRVSIVEEPLYLYVQRKGSIVQS
                     NMTLEKIKMKDEMHTSRIEFYSEKGHSFLHEKACQQYCNWIVTATTNHSKILNPNFSK
                     YLQRQFRKFAKYTRNNDIRLIVQNILGFIDIRLAAYVKSKVM"
     misc_feature    9322..9831
                     /gene="wchM"
                     /locus_tag="SPC15B_0013"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 8.2e-51"
     gene            10279..11187
                     /gene="wchN"
                     /locus_tag="SPC15B_0014"
     CDS             10279..11187
                     /gene="wchN"
                     /locus_tag="SPC15B_0014"
                     /note="member of homology group 34"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33369.1"
                     /db_xref="GOA:Q6X853"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q6X853"
                     /translation="MIEKILDSIKNHSFYSKLKDKIHRIIPLYIIKNQNIAFQQDTDI
                     AYRKLKKKFRHISLTGDELKYKMEFSNKVWICWFQGEEHAPELIKTCIQSMRNQLQGR
                     EIIVLTEKNISDYTEIPDYIIEKYKKGWISRAHYSDILRIDLLCRHGGLWVDATVLNT
                     GGDFSNLEVPLFVYKSLNLSRKDSQAIVASSWLISSYSNHPILLYTRKLLWAYWRRKN
                     SLCNYFLFHICFTIATERYPIEWSAVPTFNNHSPHILHFELNEQFSEKRWEQLKHISA
                     FHKLNHHIDYSSGVNTFYKFIVSSKV"
     misc_feature    10351..11184
                     /gene="wchN"
                     /locus_tag="SPC15B_0014"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 5.2e-127"
     gene            11192..12655
                     /gene="wzx"
                     /locus_tag="SPC15B_0015"
     CDS             11192..12655
                     /gene="wzx"
                     /locus_tag="SPC15B_0015"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippas"
                     /protein_id="CAI33370.1"
                     /db_xref="GOA:Q6X852"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q6X852"
                     /translation="MSNKISKNLAYNMGYQLIGIAAPLITSPYLSRILGAENLGIHSF
                     TMSVALYFMMFMLLGIANYGNRTIATVKREGKDILSKTFWSIYSIQLIMSILVTIAYL
                     AYLYLGAVHYKVIAILQLFLLLSNAVDITWFFYGLENFKQIVFRNTLVKLLGLFLIFL
                     CVRQGTDLWKYTFINGSVTLVGQLLLWGQLKGILTWKKIQLKELLPHIKPILILFIPV
                     LAISIFTNMDKYMLGLMVDVKQVGFYDNAGRIIEIPKALIAALGAVMLPRTSYLLAEG
                     QKEKSKYYIEVTILYVMIISSVLMFGLISVSDIFSIIFWGEEFLESGRLISAMSPAFV
                     FSVLGNIIRTQYLIPRAKDKDYVVSLIAGAVVNLVLNYFFIKPFGAMGATISTVLAEF
                     VLSGMQFWSVRRDLDLKRYLKNGLIFYLFGLIMHLIIIALKTQLPYNIMSLILLIVLG
                     GIVYVIFCCCYILMSRNLHFKLLKEKIIRKVVHKNTL"
     misc_feature    11204..12010
                     /gene="wzx"
                     /locus_tag="SPC15B_0015"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.1e-75"
     gene            13021..13998
                     /gene="wciZ"
                     /locus_tag="SPC15B_0016"
     CDS             13021..13998
                     /gene="wciZ"
                     /locus_tag="SPC15B_0016"
                     /note="member of homology group 88"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33371.1"
                     /db_xref="GOA:Q6X851"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q6X851"
                     /translation="MVTKDKGLTYNSTLHAIKVLACFSVVAIHIWLPGKIGAFYQIIA
                     RFAVPMFFLISGFYSYNISKNKIQNRIKKIFRLILRSTFFYVIIFVWMFWREGNMQFI
                     FQNFNLTNIIRFVIFNRISDLIGYLATPLWYLFAILYIYIYLYFSNKRLLLTKRWISI
                     LLLFSFIMEATISDSIFYRNFLFMGIPFFGIGILIAQKQKKIINCKIINKILILGTII
                     YPILIFLEYYILGNSFEIYISSVLATIILMIFAIKSPKAINIKILNEIGDKYATFVYI
                     IHQFIIVIFKFLVSNVYILKFGTIFVFLICCFLGVLFQFIKNRLLKRFS"
     misc_feature    13051..13989
                     /gene="wciZ"
                     /locus_tag="SPC15B_0016"
                     /note="HMMPfam hit to PF01757, Acyltransferase family,
                     score 7.1e-05"
     gene            14000..15148
                     /gene="wchX"
                     /locus_tag="SPC15B_0017"
     CDS             14000..15148
                     /gene="wchX"
                     /locus_tag="SPC15B_0017"
                     /note="member of homology group 53"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol phosphotransferase"
                     /protein_id="CAI33372.1"
                     /db_xref="GOA:Q6X850"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="UniProtKB/TrEMBL:Q6X850"
                     /translation="MVVLQNVKFLVRVVFMVIISIVLWPVRIKKNKILFINFNGKGYG
                     DNPKSICEYLRVTYPELDLVWLTKDNEDFPDGVRVVRYKSLQSFYEQASSKVWVYNVR
                     NFERLLKKRGQFYIQTWHGASSFKLIEQQADLPLKYILEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKKLSIDSDDYVILYAPTFRD
                     DGDASYLDINFERLLQSIEQEIKKKCKILIRLHPNDSHFSNNISFNHDIIDVTLFSDM
                     QELILLADVLLTDYSSAIFDFMLLNKPYVRYVNDLEKYAELRGVSDTYYELPDSIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     misc_feature    14588..15139
                     /gene="wchX"
                     /locus_tag="SPC15B_0017"
                     /note="HMMPfam hit to PF04464,
                     CDP-Glycerol:Poly(glycerophosphate) gl, score 7.7e-67"
     gene            15184..16212
                     /gene="gtp1"
                     /locus_tag="SPC15B_0018"
     CDS             15184..16212
                     /gene="gtp1"
                     /locus_tag="SPC15B_0018"
                     /note="member of homology group 40"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol-2-phosphate dehydrogenase"
                     /protein_id="CAI33373.1"
                     /db_xref="GOA:Q6X849"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="InterPro:IPR016205"
                     /db_xref="UniProtKB/TrEMBL:Q6X849"
                     /translation="MKNNDLKIGSGAIHQISATLSQNNISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     misc_feature    15205..16125
                     /gene="gtp1"
                     /locus_tag="SPC15B_0018"
                     /note="HMMPfam hit to PF01761, 3-dehydroquinate synthase,
                     score 3.1e-70"
     gene            16228..16932
                     /gene="gtp2"
                     /locus_tag="SPC15B_0019"
     CDS             16228..16932
                     /gene="gtp2"
                     /locus_tag="SPC15B_0019"
                     /note="member of homology group 41"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotidyl transferase"
                     /protein_id="CAI33374.1"
                     /db_xref="GOA:Q6X848"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="UniProtKB/TrEMBL:Q6X848"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GVSIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     misc_feature    16231..16929
                     /gene="gtp2"
                     /locus_tag="SPC15B_0019"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 8.8e-08"
     gene            16947..17780
                     /gene="gtp3"
                     /locus_tag="SPC15B_0020"
     CDS             16947..17780
                     /gene="gtp3"
                     /locus_tag="SPC15B_0020"
                     /note="member of homology group 42"
                     /codon_start=1
                     /transl_table=11
                     /product="putative phosphotransferase"
                     /protein_id="CAI33375.1"
                     /db_xref="GOA:Q4K1N0"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006357"
                     /db_xref="UniProtKB/TrEMBL:Q4K1N0"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQGSIKPTYTFKNVKEMWKGI
                     V"
     misc_feature    17004..17690
                     /gene="gtp3"
                     /locus_tag="SPC15B_0020"
                     /note="HMMPfam hit to PF00702, haloacid dehalogenase-like
                     hydrolase, score 5.9e-25"
     gene            complement(17869..18258)
                     /gene="tnp"
                     /locus_tag="SPC15B_0021"
                     /pseudo
     CDS             complement(17869..18258)
                     /gene="tnp"
                     /locus_tag="SPC15B_0021"
                     /note="member of homology group 19"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase (fragment)"
                     /db_xref="PSEUDO:CAI33376.1"
     misc_feature    complement(17878..18258)
                     /gene="tnp"
                     /locus_tag="SPC15B_0021"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 7.3e-05"
                     /pseudo
     gene            18223..18375
                     /gene="tnp"
                     /locus_tag="SPC15B_0022"
                     /pseudo
     CDS             18223..18375
                     /gene="tnp"
                     /locus_tag="SPC15B_0022"
                     /note="Lone member of homology group 0232"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase (fragment)"
     gene            18577..>18624
                     /gene="aliA"
                     /locus_tag="SPC15B_0023"
     CDS             18577..>18624
                     /gene="aliA"
                     /locus_tag="SPC15B_0023"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33378.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ89"
                     /translation="MMKSSKLLALAGVTLL"
BASE COUNT     6272 a   2490 c   3532 g   6330 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attctcgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga agatgaacat
      301 aaagaagcgt gtccttagtg caggtctgac ttttgcatct gctttgcttt tagctgcttg
      361 cgaccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaattac ctattagact attaaactga taatatagtc aatcgaaaca agaacaagac
      481 aaaagagcct tgtaaaaggt attgcaactt ggtaatacct tttatgaggt gctttttgat
      541 atgagtccat gttttctcaa taggattgta ctcaggtgag tagggaggaa gaggtaaaag
      601 tttattccca aactcttcac acaagagttc tagcttcccc attctatgga atcttacatt
      661 atccataata ataaccgatg gtgtggttaa tgttggtaag aaaaacttct gaaaccatac
      721 ttcaaaaaag tcgctcgtca tcgtctcttc gtaagtcatt ggagcgatta actcaccatt
      781 tgttagacct gcaaccaaag aaatcctctg atatcttctt ccagatactt tacctcttat
      841 taactgacct tttaatgagc gaccatattc tcgataaaaa taagtatcga atcctgtttc
      901 gtcaatctaa acaggtgcta ggtgctttaa tctattaaaa ttcttaagaa ataaggctac
      961 tttttctggg tcttgttcat aattagattg aaactagaat agtacacctc tgcttctaaa
     1021 acattgttag aaatcgattt gactgtcctg atcgatttat catgttctta tttcatttta
     1081 ctatattttt gtttcgcggg aagtctacta agatacttaa agatgcagat agtgaaaaaa
     1141 ggtgtagaca ttaccgtaaa aaagtgatat aatcgtatga tgttcaatgt ataggtgtta
     1201 atcatgagta gacgttttaa aaaatcaagt tcacagaaag tgaagcgaag tgttaatata
     1261 gttttgttga ctatttattt attgttagtt tgttttttat tgttcttaat ctttaagtac
     1321 aatatccttg cttttagata tcttaattta gtggtaactg cgttagtcct actagttgcc
     1381 ttggtagggc tactcctgat tatctataaa aaagctgaaa aatttactat ttttctgttg
     1441 gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag tacagcagtt tgttggactg
     1501 accaatcgtt taaatgcgac ttctaattac tcagaatatt caatcagtgt cgctgtttta
     1561 gcagatagtg atatcgaaaa tgttacgcaa ctgacgagtg tgacagcacc gactgggact
     1621 gataatgaaa atattcaaaa actactagct gatattaagt caagtcagaa taccgatttg
     1681 acggtcgacc agagttcgtc ttacttggca gcttacaaga gtttgattgc aggggagact
     1741 aaggccattg tcttaaatag tgtctttgaa aatatcattg agtcagagta tccagactac
     1801 gcatcgaaga taaaaaagat ttataccaag ggattcacta aaaaagtaga agctcctaag
     1861 acgtctaaga atcagtcttt caatatctat gttagtggaa ttgacaccta tggtcctatt
     1921 agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg tcaatcgaga taccaagaaa
     1981 atcctcttga ccacaacacc acgtgatgcc tatgtaccaa tagcagatgg tggaaataat
     2041 caaaaagata aattaaccca tgcgggcatt tatggagttg attcgtccat tcacacctta
     2101 gaaaatctct atggagtgga tatcaattac tatgtgcgat tgaacttcac ttctttcttg
     2161 aaaatgattg acttattggg aggggtagat gttcataatg atcaagagtt ttcagctcta
     2221 catgggaagt tccatttccc agtagggaat gtccatctag actctgagca ggctctaggt
     2281 tttgtacgtg aacgctactc actagccgat ggagaccgtg accgtggtcg caaccaacaa
     2341 aaggtgattg tggctatcct tcaaaaatta acgtcaaccg aagcactgaa aaattatagt
     2401 acgatcatta atagcttgca agattctatc caaacaaata tgccacttga gactatgata
     2461 aatttggtca atgctcagtt agaaagtgga gggaattata aagtaaattc tcaagattta
     2521 aaagggacag gtcggacgga tcttccttct tatgcaatgc cagacagtaa cctctatgtg
     2581 ttggaaatag atgatagtag tttagctgta gttaaagcag ctatacagga tgtgatggag
     2641 ggtagatgaa atgatagaca tccattcgca tatcgttttt gatgtagatg acggtcccaa
     2701 gtcaagagag gaaagcaagg ctctcttggc agaatcctac aggcaagggg tacgaatcat
     2761 tgtctctacc tctcaccgtc gcaagggcat gtttgaaact ccggaagaga agatagcaga
     2821 aaactttctt caggttcggg aaatagctaa ggaagtggcg agtgacttgg tcattgctta
     2881 cggagctgaa atttactaca caccagatgt tctggataag ctggaaaaaa agcggattcc
     2941 gaccctcaat gatagtcgtt atgccttgat agagtttagt atgaacactc cttatcgcga
     3001 tattcatagc gccttgagca agatcttgat gttgggaatt actccagtca ttgcccacat
     3061 tgagcgctat gatgctcttg aaaataatga aaaacgcgtt cgagaactga tcgatatggg
     3121 ctgttacacg caagtaaata gttcacatgt cctcaaaccc aaactttttg gcgaacgtta
     3181 taaattcatg aaaaaaagag ctcagtattt tttggaacgt gatttagttc atgtagttgc
     3241 aagtgacatg cacaatttag acagtagacc tccatatatg caacaggcat atgatatcat
     3301 tgctaagaaa tatggagcga aaaaagcgaa agaatttttt gtagataatc ccagaaaaat
     3361 tataatggat caattaattt aggagaaaat atgaaggaac acaacacttt ggaaatcgat
     3421 atattgcaac tattcagagc tttatggaaa agaaagttgg tcattttatt agtggcaatt
     3481 ataacttctt cagttgcttt tgcctacagt acttttgtta tcaaacctga gtttactagt
     3541 acgactcgga tttatgtagt taaccgtaat caggaagaga agtctggttt aaccaatcaa
     3601 gacttgcagg caggaactta tctggtaaaa gactaccgtg agattatcct ttcgcaggat
     3661 gttttggagg aagttatttc tgatttgaaa ctagatttga cgccaaaagg tttggctaat
     3721 aaaattaaag taacagtacc agttgatacc cgtattgtct ctgtttcagt taatgatcga
     3781 gttcctgaag aggcaagccg tatcgctaac tctttgagag aagtagctgc tcaaaaaatt
     3841 atcagtatta ctcgtgtttc tgatgtgaca acactggagg aggcaagacc ggcgatatca
     3901 ccgtcttcgc caaatattaa acgcaatata ctaattggtt ttttggcagg gggggttgga
     3961 actggtgtta tagttcttct tcttgaactt ttggacactc atgtgaaacg tccggaagat
     4021 atcgaagata cactgcagat gacacttttg ggagttgtac caaacttgag taagttgaaa
     4081 taggagagag gaatgccgac attagaaata gcacaaaaaa aactggagtt cattaagaag
     4141 gcagaagaat attacaatgc cttgtgtaca aatatacagt tgagcggaga taaactaaaa
     4201 gtaatttccg ttacttctgt taaccctggg gaaggaaaaa caactacttc cgtaaatata
     4261 gcaaggtcgt ttgcgcgtgc aggctataaa actcttttga tcgatggcga tactcgaaat
     4321 tcagttatgt caggattttt taaatctcgt gaaaaaatta cagggctaac agaattttta
     4381 tctgggacag ctgatttatc tcacggttta tgtgatacaa atattgaaaa tttatttgta
     4441 gttcaatcgg ggtctgtatc accaaaccct acagccttgt tacaaagtaa aaattttaat
     4501 gatatgattg aaacattgcg taaatatttt gattatatca ttgttgatac agcacctatt
     4561 ggaattgtta ttgatgcggc aattatcact caaaagtgtg atgcgtccat cttggtaaca
     4621 gcaacaggtg aggtgaataa acgtgatgtc caaaaagcga aacaacaatt agaacaaaca
     4681 gggaaactgt ttttaggtgt cattctcaat aaatttgatg ttcaacataa aaaatatggt
     4741 tcttacggtg actatggtaa ttatggtaaa aaataactta ggaaagattt tatggatgaa
     4801 aaaggattga aaatttttct ggcagtatta cagagtatta ttgtcatttt attggtttat
     4861 tttcttagct ttgttagaga gacagaactt gaacgttctt cgatggttat actatacctt
     4921 ctccactttt ttgtattcta ttttagttcc tatggtaata atttttttaa aagagggcac
     4981 ttagttgagt ttaatagtac tataagatat atttttttct ttgcaatagc tataagtgta
     5041 ttaaactttt ttatagcgga acggtttagt atctctagaa gaggaatggt atacttctta
     5101 actttagaag gaatatcctt atacttgtta aatttcttag taaagaaata ttggaagcat
     5161 gtgtttttta atctaaaaaa tagcaagaaa attttactgt taacagtaac gaaaaatatg
     5221 gaaaaagttc ttgataaatt gctagaatct gatgaacttt catggaaatt ggtagcagta
     5281 agtgttttgg ataaatctga ttttcaacat gataaaatac ctgtaattga aaaggaaaaa
     5341 attattgaat ttgcaacgca tgaagttgtg gatgaggtgt ttgtcaatct tccaggagag
     5401 agctacgata ttggagaaat tatctctagg tttgagacaa tggggataga tgtaactgta
     5461 aatcttaaag catttgataa gaatttgggt cgcaataaac aaattcatga gatggtagga
     5521 ttgaatgtag tcactttctc tacaaatttt tataaaacta gtcatgtgat ttcaaagaga
     5581 attctcgata tttgtggtgc cactattggc cttgttcttt ttgctatagc tagtctagtt
     5641 ttagttccat tgattcgtaa agatggcgga ccagctattt ttgctcaaac tcgtataggg
     5701 aaaaatggtc gacattttac cttttataaa ttccgttcga tgaggatcga tgctgaagct
     5761 atcaaagaac agttgatgga tcaaaatacg atgcaaggtg gtatgtttaa gatggacaat
     5821 gatcctcgtg ttacaaaaat tggtcgcttt attcgtaaaa ccagtttgga tgaattgccg
     5881 cagttttgga atgtctttat aggagatatg agtttggtgg gaacacgtcc acctacagta
     5941 gacgagtatg atcagtatac tccagaacag aaacgtcgac tcagctttaa acctggtatt
     6001 acaggtttat ggcaggttag cggccgtagt aaaataaccg attttgacga tgttgtaaaa
     6061 ttagatgtgg cttatattga taattggaca atctggaaag atattgaaat tttgcttaaa
     6121 actgttaaag ttgtatttat aagagatgga gcgaagtaag gaatgaaagt atgtctagtt
     6181 ggatctagtg gaggccattt aactcatttg tatttattaa aacctttctg gaatgataaa
     6241 gaaagatttt gggttacttt tgataaggcg gacgctcgga gtgtactctc tgaggaagtt
     6301 gtatatccct gttattatcc aaccaatcgt aatataaaaa atttaataaa aaatactttt
     6361 ctcgcctata aaattttaaa aaaagagaga ccagatttga ttatttcttc tggtgccgct
     6421 atcgctgttc ctttctttta tattgggaag ttatttggat caaagacagt gtatatagaa
     6481 gtgtttgata gaattgatgc ttcaacactg acaggaaaac ttgtttatcc agtaacggat
     6541 aggtttattg tacaatggga agaaatgaaa aaagtatacc caaaagcaat taacctagga
     6601 gggatattct aatgattttt gtgactgtag gtacacacga acaacaattt gatcgattga
     6661 ttaaagaagt tgattatcta aaaaaagaaa atcttattca agatgaagta tttattcaaa
     6721 taggatattc cagttatatt ccgaaatatt gtgagtggga aaagataatt tcttatgaaa
     6781 aaatgaatca attgattaag gaatcagata ttatcattac tcatggtgga ccagcgacgt
     6841 ttatgggggt tattgctaaa ggaaaagttc cgatagttgt tccgaggcaa aaaaaatttg
     6901 gagagcatgt gaatgaccat cagcttcaat tcgtaaaact gacgaaagaa atatacaatt
     6961 ttatagtcat agatgatatt tccgacttat atttaagtat acgtgatttt aaggataaat
     7021 attttggaat ttgtttgaac aatgaaagat ttaatctaca ttttaatgcg gaaattaata
     7081 aactatttga aggaaataaa gtagatgaaa attagaatag agcctcaata ttttctttat
     7141 aagtaccttt ggcttatcat actgctccca aaacagttta tgcaattaat attattttct
     7201 ttaattgtct taattctatt accggtctat ataaaagata gacaaatttc caaaatagat
     7261 gcaccgtctt tttatatagt tctatgggtc atgatgtatt ctatatcaat aatttggaat
     7321 tttttaatta gtggcttacc tattcaagtg ttgttttcag atttgagtaa ggcattcaat
     7381 tggatattag cagtattttt ttataattat tatttgaaaa atcccattaa cgttgacaag
     7441 ataaagaaat atatgtttta taatttcgct atattagtta ttattgttgc tttattctat
     7501 gttcaaagag gcgctaatgt agtattgttt ggaagaagct tattaggttg ggacggattc
     7561 gtatcagcta ccagttacgg agtaagatat gcaggatttt tagaatattc aacattaaat
     7621 gggcagttga ttcttttttt gttaccgtta attaggttat ttaaacttag tttttttaca
     7681 caagtaacta ttcttgcttt tttgctacag gttttagtat tgagtaaatc tagaatagct
     7741 attattgctc tgattatata catagtattt gtagtaatgg ttcagattac ttcaattaat
     7801 aagcggatga ttgtagcgtt ttatccaact atacctctta tattgcttta taattgggaa
     7861 aaaattaaac atatcttttt tcaaatgttt aattcaagaa caggtagtaa tgtgacacgt
     7921 tttatagtgt acgaagaatc tcttaaagct attaatgggc tgggaatttt acttggagca
     7981 ggaatcagaa cacaatctac agtaggtata ttattaggat cacattcaat gtatattagt
     8041 tttatttata ggacagggat tttaggaagt ataataatag taatactgtt ctattatttg
     8101 ttttctaaat ttttaaaaag tgccccatct ggaaagttaa tcagtatagg ctatatttta
     8161 gctttattgg tgttttggct ttttgaagaa ttagatccac attattggtg tttaatttta
     8221 tttttttcaa caataagtat tttcataaac aatagaaaag aggaaatagt tggatgatag
     8281 aagtatcaat cataattcca atatacaatg ctgaaaaaac tattaaaaat tgtgttgata
     8341 gtgccttaaa gcaaaattta gaatctcttg aagtgatttt ggtgaatgat gggtctaacg
     8401 attctacagc agaaattttg aaccagtacg acaggaattc aagggttaag atttttcatc
     8461 agcttaataa aggggtgtct actgctagaa ataaggggtt atctcatgct agtggagagt
     8521 atgtattttt tctagattca gatgatattt tagatgatgg tatgctttct aaaatgtacc
     8581 aatttgtaaa aaataataaa gttgatctct tatcttgttg gcataaagaa cctgctacaa
     8641 ctcaatacgg tggaaatgag aataagtcaa cttcatttat tgcacgtaca agagaagaaa
     8701 taggtgctca ttttgttgat atctttccga gaagtgcttg tgccaaattg ttttttcgca
     8761 aaataattga agaaaataat attacttttt cgactgagat gtcactaggt gaagatatgt
     8821 catttgtgta tcaatactta atggtttcta aaagtattgg agttattgac ggggtgtatt
     8881 ataatattca aaatgtaaat ccacagtcgt tatctaagcg ctatgtgcag aatattgaaa
     8941 attccctaat aattcagaac cagttatgga atcaactgtt ggaagtttat cctaaaattg
     9001 aggagaacta ctataagcaa catatggatt ttagatttta ccttgctaac ttgtatgtaa
     9061 ataatttatt taaatttgat tctccgtatt catcaaaaga aaaactagac caaattgctc
     9121 aacaattaaa aaagtataga ttatttttag atgaaaaagt cagcaaagaa aagatgccta
     9181 aaaatataaa tgagatgatt gttttttatt tactaaaatt gaaaattcca gtgttgattt
     9241 attcttttta ttcgtttaaa gagtggtgga agagaagaaa aattaaaaat gaaggataaa
     9301 taagttatgg aagatttgat aagcattgtt gttccagtct ataacgtgga aaaatattta
     9361 aaaaaatcaa tagaaagtat tttgaatcag acttatcaaa atatcgagat tttattggtt
     9421 gatgacggaa gcacagatag tagtgggaaa atttgtgaat catttagtaa agttgatcct
     9481 aggataagag tatttcataa agaaaatggt ggtttatcag atgctcggaa ttttggaatt
     9541 gagcaaatga aaggtcaata tgtagcgttt attgatagcg atgactacat atctaaggat
     9601 tatgtctgga agttgtattc ttctataaaa aataatgatt ccgaggtgtc gatttgttct
     9661 tttttattag tcgatgaaaa aggggaaaaa ataaaagatg agctattaga ttcgggaaaa
     9721 atatgcttga ctggtcaaca aatattagaa aaagtattaa cagccgacgg ctatcgctat
     9781 gttgttgctt ggaataagct ttatcggtca actttatttg aaaaattaaa atttaaaaaa
     9841 ggaatgttgt atgaggatga atttcttaac tatcctctat tttgggactg taaaagggta
     9901 tcaattgtag aggagccgtt atatttatac gttcaacgaa aaggaagcat tgtacaaagt
     9961 aatatgactt tagaaaaaat aaagatgaag gatgagatgc atacttcacg cattgagttt
    10021 tattcagaaa aggggcattc ttttttgcac gaaaaagcgt gtcaacagta ctgcaattgg
    10081 attgttacag cgactaccaa tcatagtaag attttaaatc ctaatttttc aaagtattta
    10141 caacgacagt ttagaaagtt cgctaaatat acacgaaaca atgatattag actaattgta
    10201 cagaacattc taggatttat agatattcgt ttagcagctt atgtaaaatc aaaagtaatg
    10261 tagagtatag gaaacataat gatagaaaaa attttagatt ctattaaaaa tcattctttt
    10321 tatagtaaat tgaaggataa aattcataga attattccat tatatattat aaaaaatcaa
    10381 aatatagctt ttcaacaaga taccgatata gcatatagaa aactaaagaa gaagtttaga
    10441 catatttcgt tgactggaga tgagcttaaa tataaaatgg agttttcaaa taaagtttgg
    10501 atttgttggt ttcagggaga agagcatgcc ccagagttaa ttaaaacatg tattcaatca
    10561 atgaggaatc aacttcaagg aagagaaatc attgtgttga cagaaaaaaa tataagtgat
    10621 tatacagaga ttccagacta tattattgaa aaatacaaaa aaggatggat ttctcgtgcg
    10681 cattactctg atatccttag gatagatctt ctatgtcgcc atggaggatt atgggtagat
    10741 gcaacagtgt tgaatacagg aggagatttc tcaaatcttg aggtaccact ttttgtatat
    10801 aaatctttga atttatcaag aaaagattca caagctattg tagcatcaag ttggttaatt
    10861 tcgtcatata gtaatcatcc tatattactc tatacgagaa aactcctatg ggcctactgg
    10921 cgaagaaaaa atagtttatg taattatttt ttgttccata tatgttttac aatagctaca
    10981 gagcggtacc caatcgaatg gtctgctgtc cctactttta ataatcattc tcctcatata
    11041 cttcattttg agttgaatga acaattttcg gaaaaacggt gggaacaact gaagcatatt
    11101 tcggcgtttc ataaattaaa tcatcatata gattattcta gcggtgttaa cactttttat
    11161 aagttcatag tatcttcgaa agtttagaaa aatgagtaat aaaattagta aaaatttagc
    11221 ctacaatatg gggtatcagt taattggtat tgcagctccc ttgataactt ctccttattt
    11281 atcacggata ttaggtgctg aaaatttagg tattcattct tttactatgt cggttgcact
    11341 ttactttatg atgtttatgc ttcttggaat tgcaaattac ggaaatagaa caattgcgac
    11401 tgttaaacga gaaggaaagg atattctatc aaaaacgttt tggagtatct actctatcca
    11461 gttgataatg tctattctgg taactatagc ttatcttgct tatctatatt tgggggcagt
    11521 acattacaaa gttattgcaa tattacaact ctttttattg ttatcaaatg ctgttgatat
    11581 tacttggttt ttctatggat tagaaaattt taagcaaatc gtttttagga atacattagt
    11641 caaactttta ggattatttt taattttttt atgtgtgcgt caaggcacag atttatggaa
    11701 atacacattt ataaacggat cagtaacttt agttggccaa cttttactat ggggacaatt
    11761 aaaaggaata ttaacttgga aaaaaattca attaaaggaa ttactacctc atatcaagcc
    11821 aattttaatt ctttttattc ctgtactagc cattagtatt tttactaata tggataaata
    11881 tatgcttggt ttaatggttg atgtaaagca ggttggattt tatgacaatg caggtagaat
    11941 tattgaaatt cctaaagctt tgattgcagc tttaggggcc gttatgttac caagaacttc
    12001 ctatttatta gcggaaggac agaaagaaaa gagtaaatac tacatagagg taacaatttt
    12061 atacgtgatg attatttcta gtgtattgat gtttgggcta atatcggtat ctgatatttt
    12121 ttccattata ttttggggag aagaatttct tgaatcaggt agattgattt ctgctatgtc
    12181 tccggctttt gtcttctctg tattaggaaa tatcattagg actcagtatt tgattcctag
    12241 agctaaggat aaagattatg tagtgtctct aattgcgggg gctgttgtta atctagtgct
    12301 aaactatttt tttataaaac cttttggtgc tatgggagca acaattagta cagttttggc
    12361 agaatttgta ttgtctggaa tgcagttttg gtcagtaaga agagacttag atttaaaaag
    12421 atatttgaaa aacggtttga tattctacct atttggtctg attatgcacc tcattattat
    12481 agcactcaaa actcagttac catacaatat aatgagtctt attttactaa tagttttggg
    12541 tggaatagta tatgttattt tttgttgttg ctatatttta atgtcaagaa atttacattt
    12601 taagttattg aaggaaaaga ttatacgaaa ggttgtacat aaaaatacat tataaaatat
    12661 tagtttatct tatttagttg gatactatta aataaacgaa agtatttgaa actttggtaa
    12721 ttgagattat agagattata gagataaact aagctatatt atagcttcat tattaaagta
    12781 agaatatcgg tgcagtgtag ttaacgaata atgtgagtac tcatttctta gatggagcta
    12841 ggggtcatta taagggattg atatgacatt ttgagtaagt tacagctaga gtttaggttt
    12901 gattatatca gatatttaga tgatttggaa aataataaaa taagttggga actatttttt
    12961 tattgttttg agtgacaggt ttgattttgg gaaatgtatt ttgttaaata ggtaggaaag
    13021 atggttacta aagataaagg attaacatat aatagtactt tgcatgcaat aaaagtatta
    13081 gcatgtttta gtgttgttgc tattcatata tggctaccag gaaaaattgg agcgttttat
    13141 caaataatag cacgatttgc agttccaatg ttctttttga tttctggctt ttattcatat
    13201 aatatttcaa agaataaaat acagaataga attaaaaaaa tatttagatt gatattaaga
    13261 agtacatttt tttatgtaat aatatttgta tggatgtttt ggagagaagg taatatgcag
    13321 tttatttttc aaaactttaa tttaacaaat attataagat ttgtgatttt taataggatt
    13381 tcagatttaa taggctatct agcaacaccg ttgtggtatt tatttgctat attatatata
    13441 tatatatatc tttatttttc caataaaaga ctactattga caaaacgatg gatttctata
    13501 cttttactat tttctttcat tatggaagct acaattagcg attcaatttt ttatagaaat
    13561 tttttattta tgggaatacc attttttgga ataggaattc ttattgcaca gaagcaaaag
    13621 aagattatta attgtaaaat aataaacaaa atattaatct tgggaacaat tatctatcca
    13681 atactaatat ttttagaata ttatatcttg ggtaattctt ttgagatcta tataagttct
    13741 gtgctagcaa ccataatatt gatgattttc gcgattaaat cacctaaagc gattaatata
    13801 aaaatactga atgaaattgg agataaatat gcgacttttg tttacattat acaccagttt
    13861 atcattgtga tatttaaatt tttagtatct aatgtttata ttctcaaatt tgggacgata
    13921 tttgtctttt tgatatgttg ttttctaggg gttctatttc aatttatcaa aaacagacta
    13981 ttaaaaaggt ttagttaaga tggttgtttt acaaaatgtt aaatttttag taagagttgt
    14041 ttttatggtt attatcagta tagtgttatg gcctgttcgg ataaagaaga ataagatact
    14101 atttattaat tttaatggta agggatatgg tgataatccg aaaagtattt gtgagtatct
    14161 tcgagttaca tatccagagt tagatttagt ttggcttaca aaagataatg aagattttcc
    14221 agatggagtg agagttgtaa gatataaatc tctacaatct ttttatgagc aagctagttc
    14281 gaaggtttgg gtttataatg taagaaattt tgaaagacta ctaaaaaaac gcggacagtt
    14341 ttatattcaa acttggcacg gtgcttctag ttttaaactg atagaacagc aggctgattt
    14401 accattaaaa tatattttag aagcaaagta tgatgcaaga gtcacagata taatgatttc
    14461 agatagcaga aaacaaactg aagaatttca aaagtatttt tggtattcag gagaaatttt
    14521 tgaggtgggg atgccgagaa atgatgcctt gtttcactat aaggaagact acgacaagtt
    14581 aaataatatc agaaaaaaac taagcattga ttcagatgat tatgttattt tatatgcccc
    14641 tactttcaga gatgatgggg atgcatctta tttagatata aattttgaac ggcttttgca
    14701 aagtattgaa caagaaatta agaagaaatg taaaatttta attagattac atcctaatga
    14761 ctctcatttt agtaataata tttcttttaa tcatgacata attgatgtta cgctattctc
    14821 agatatgcag gaacttatat tattggcaga tgttttactg acagattatt cttccgcgat
    14881 atttgatttt atgcttttaa acaagcctta tgtcagatat gtgaatgatt tagaaaaata
    14941 tgctgagctt aggggggtat cagatacata ttatgaattg ccggattcta ttattaaaac
    15001 tgctgaagaa ttgtatgact tactgcctaa aaaaatagaa aattttgatt atgattctat
    15061 aaaaaaatat agaaatgaaa tactgtgtcc aatctttaat ggaaccgcta gtgaaaatgt
    15121 aggaaggaga ataattcaag agttgtgaag taaaacattg ggttattttt aaggtaacga
    15181 gatttgaaaa ataatgattt aaagatagga agtggagcta ttcatcaaat ctccgctaca
    15241 ctttctcaaa ataatatttc gggaaagatt ttatattgtg ctgatccagt tgtcgatgac
    15301 ttgtacggtt cgatagtacg ttcacaaata gaggaaattg gtcgggtaaa ggaagaaagt
    15361 tgcaattata atactattgc ttatgcgatg aatatagcag aaagggctat tgccacagat
    15421 attgactgta ttgtgggaat gggaggaggt cgtgttttag atgtctgcaa gtatgcatct
    15481 tttatttcga aacgtcctta cctatcgatt ccgacaacag cagcaaatga tggcattgct
    15541 tccccagttg ctgttttgaa aaggcaggat gatagaccaa aaagcttagg ggcggctatc
    15601 ccctcaatga cactaattga tattgatgtt attgcatcag gacctataca aaatataaaa
    15661 gctggtatcg gtgatacaat atccaattac actgcattga aagattggga gttggcagtt
    15721 gagcgaggga aagatgagat gcatggtttt gcatatctaa tgtcgcaaaa ttctttagat
    15781 gctttaatga aaacgaagta taattctatt acccctgatt ttattgaagt tttggtaaac
    15841 tctttagttt tatcaggcat tgcaatggat tttgcgggaa gtagtagacc tgtcagtggg
    15901 tcagagcact tatttagtca tgcattagat tactatggtt ctacaaggaa tcttcatgga
    15961 attcaggttg cattaggtac agtcgcagtt ttgaaattaa ttgaaaattc tgttgatact
    16021 gtagtggatt acttgcaaag atttgaggtt catattaacc cgaaactttt ggggatagat
    16081 gaagagttgt ttatttattg tatgcaacat gctacaaaaa tgagaagtaa tcgctatacc
    16141 tatctgcatg aagttgatct tagcacagat agattgaaac aaatatataa ggaactcata
    16201 agcgagttgt agaaaagaga ggaaaaaatg aaagcactta ttttagcagc agggttagga
    16261 acacgtctag ctccaattac caatgaggta ccaaaatctt tggtaccagt caatggtaag
    16321 ccaattttga tgaaacaaat tgaaaattta tatcaaaata atattacaga tattacgatt
    16381 attgctggat ataagtcatc tgtattaaca gatgcagtta ctgaaaagta tccagaaatt
    16441 aatattattg ataatgttga ttttaaaacg actaataata tgtattcagc ctatctagga
    16501 aaagctgcaa tgggtgatag tgacttctta atgatgaatg cagatgtatt ttatgatgct
    16561 tctgttatta aaagtctgtt gcttcataaa gctccaaatg caattgtaac tgatttaggt
    16621 atttatattg aagagtctat gaaagtcgta gaaaaaaatg gtcgtttagt agaaatttct
    16681 aaacagattt cacctgagga aactttagga gtttctattg atgtttataa attctcttat
    16741 gaagcaggtg ctcgattctt tgaaaagtgt aaggaattta ttgaagataa acgagaactt
    16801 caaatgtgga gtgaggttgc tcttaatgca attctttctg aagttgaatt tgtagcatgt
    16861 ccattagagg gtcgttggtt agaaattgat aatcatgaag acttagttgc tgcagaaaaa
    16921 ctatttgctt gaaccgaata cggagaatga aattgacaaa tagagttgat tattttggtg
    16981 ctgatattag tgaacttcag aataaaaaat tattcttatt tgatatggat ggtaccattt
    17041 atgaagaaga taggttgttt gagggtactc tcgaattatt agactatatt cataatattg
    17101 gcggtgagta tatttttatt acaaacaatt catctaagtc tgttgttgac tatgtagaaa
    17161 aagttaacag attaggtatt aaagctgaac gagataattt ttttacctct gctcaagcca
    17221 caattgttta tattaaagaa aattatccta aatctaaagt ttattgccaa ggaacaaaat
    17281 ctttgataaa agaactatct gacgcaggaa ttgatgtaac tgagcaagtt agtgctgata
    17341 tagatgttgt tcttgttggt tttgatacag aattaaccag tgataaaatt cgcaatacct
    17401 gcgagattct atcaacaaag gacgtacctt tcatagctac taaccctgat attcgctgcc
    17461 cagtatcgtt tggattcatc ccagattgtg gttctatttg tgatatgatt agtaaatcag
    17521 tcgataggaa acctgtttac ataggtaaac ctgaacctac gatggttgat attgttcgaa
    17581 aaaaattaaa ttattctcta tttgaaacag ttgtgattgg agatcgcttg tatacggata
    17641 tcatgactgg tataaatgca ggagtaactt cagtttgtgt gctgacagga gaagcaacgg
    17701 tgaatgatat tcaacaaggt agtataaaac cgacttatac atttaaaaac gtgaaagaaa
    17761 tgtggaaagg aattgtctga ttttttcatt ctgaatagtg aattcatgaa tactgtcaaa
    17821 atactcgtat gtatttaaat tgattttatt attagacttc ctgcaaaact agaatcctag
    17881 ttcatgattg ataatagcag caatcaaatt cattcgtaat ccgaagcgtt tacgatgatt
    17941 tcgataggtt gttgaaaaca ttttaaacgt ttttactttg gcaaagatgt tctcgacctt
    18001 gcttctctcc ttggatagcg catggttata ggctttatct tcaactgtta gcggcttgag
    18061 tttgctggat ttacgtggag tttgtgcttg aggatatatc ttcatgagcc cttgataacc
    18121 actgtcagcc aagattttac cagcttgtcc gatatttctg cgactcattt tgaacaactt
    18181 catatcatga caatagttca cagtgatatc caaagaaaca attctccctt gacttgtgac
    18241 aatcgcctga gccttcatag cgagaaatat ctattctatc ttctagaatg tcttccaaac
    18301 gaggaaactc tcgtaaacaa agaggtttta gaggcttatt taccatggac taaagttgta
    18361 caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt ctctagtctg
    18421 gagatttttc aatatacttc gttattgggc gcttacaatg atattcatat tttttgcaaa
    18481 gatgttgttt gaaaaataat tttcaaaaat tctgaaaatt ctgttgacaa ctttctgaaa
    18541 agagtctata atggagagaa agttttaaag gagaaaatga tgaaaagttc aaaactactt
    18601 gcccttgcgg gcgtgacatt attg
//
