LOCUS       CR931667               21730 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain R105 (serotype 16a).
ACCESSION   CR931667
VERSION     CR931667.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21730)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 21730)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..21730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="R105"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC16A_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC16A_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI33427.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..466
                     /gene="aliB"
                     /locus_tag="SPC16A_0002"
                     /pseudo
     CDS             293..466
                     /gene="aliB"
                     /locus_tag="SPC16A_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(459..980)
                     /gene="tnp"
                     /locus_tag="SPC16A_0003"
                     /pseudo
     CDS             complement(459..980)
                     /gene="tnp"
                     /locus_tag="SPC16A_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            1197..2642
                     /gene="wzg"
                     /locus_tag="SPC16A_0004"
     CDS             1197..2642
                     /gene="wzg"
                     /locus_tag="SPC16A_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33430.1"
                     /db_xref="GOA:Q4K1I6"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K1I6"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKIIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESEGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1197..1313
                     /gene="wzg"
                     /locus_tag="SPC16A_0004"
                     /note="Signal peptide predicted for SPC0767 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1401..1748
                     /gene="wzg"
                     /locus_tag="SPC16A_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 6.7e-65"
     misc_feature    1926..2369
                     /gene="wzg"
                     /locus_tag="SPC16A_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 2.2e-69"
     gene            2644..3375
                     /gene="wzh"
                     /locus_tag="SPC16A_0005"
     CDS             2644..3375
                     /gene="wzh"
                     /locus_tag="SPC16A_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33431.1"
                     /db_xref="GOA:Q4JZ86"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ86"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHTGLSNILMLGITPVIAHIERYDALENNEKRVCELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPHMAEAYDLVT
                     QKYGEAKAQELFVDNPRKIIMDQLI"
     misc_feature    2647..3255
                     /gene="wzh"
                     /locus_tag="SPC16A_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 7.1e-37"
     gene            3384..4076
                     /gene="wzd"
                     /locus_tag="SPC16A_0006"
     CDS             3384..4076
                     /gene="wzd"
                     /locus_tag="SPC16A_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33432.1"
                     /db_xref="GOA:Q4K1I4"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K1I4"
                     /translation="MKEQNTLEIDVLQLFRILWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVFLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     misc_feature    3402..3818
                     /gene="wzd"
                     /locus_tag="SPC16A_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1.3e-53"
     misc_feature    3924..4001
                     /gene="wzd"
                     /locus_tag="SPC16A_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4086..4769
                     /gene="wze"
                     /locus_tag="SPC16A_0007"
     CDS             4086..4769
                     /gene="wze"
                     /locus_tag="SPC16A_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33433.1"
                     /db_xref="GOA:Q4JZ84"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ84"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFAYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            4785..6152
                     /gene="wchA"
                     /locus_tag="SPC16A_0008"
     CDS             4785..6152
                     /gene="wchA"
                     /locus_tag="SPC16A_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33434.1"
                     /db_xref="GOA:Q4K1I2"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K1I2"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKISHVISKRILDICGATIGLVL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFI
                     RDGAK"
     misc_feature    5568..6149
                     /gene="wchA"
                     /locus_tag="SPC16A_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 5.9e-145"
     gene            6156..6557
                     /gene="gct"
                     /locus_tag="SPC16A_0009"
     CDS             6156..6557
                     /gene="gct"
                     /locus_tag="SPC16A_0009"
                     /note="member of homology group 28"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol-1-phosphate biosynthetic protein
                     Gct"
                     /protein_id="CAI33435.1"
                     /db_xref="GOA:Q4K1I1"
                     /db_xref="InterPro:IPR004820"
                     /db_xref="InterPro:IPR004821"
                     /db_xref="InterPro:IPR006409"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="UniProtKB/TrEMBL:Q4K1I1"
                     /translation="MKKVITYGTFDLLHYGHINLLKRAKSLGDYLIVVISTDEFNWNE
                     KQKKCYFTYEQRKTLVEAVRYVDLVIPEESWEQKVTDVHEYHIDTFVMGDDWKGKFDF
                     LEKEGVEVVYLSRTPEISTTEIKNSLATREY"
     misc_feature    6168..6536
                     /gene="gct"
                     /locus_tag="SPC16A_0009"
                     /note="HMMPfam hit to PF01467, Cytidylyltransferase, score
                     5.2e-28"
     gene            6580..7401
                     /gene="wcxR"
                     /locus_tag="SPC16A_0010"
     CDS             6580..7401
                     /gene="wcxR"
                     /locus_tag="SPC16A_0010"
                     /note="member of homology group 151"
                     /codon_start=1
                     /transl_table=11
                     /product="putative LicD-family phosphotransferase"
                     /protein_id="CAI33436.1"
                     /db_xref="GOA:Q4K1I0"
                     /db_xref="InterPro:IPR007074"
                     /db_xref="UniProtKB/TrEMBL:Q4K1I0"
                     /translation="MTDELERLHNLELLLASEVLKICGKYNLKIVMLAGTFLGAIRHN
                     GFIPWDDDMDFGMPREDFERFKELCVSDLDREKYFLQTDQTDLNYPFNFVKLRLNNTH
                     VSEEFSLDANVHDGIYIDIFPIDNICPKPFRRFIQLKGFWLFRNLLWIKCGYGDNDRK
                     KRLAYKLAKLATHVFSISFLKKMKEKCILLGQSTNADNVVVSDGSYGIKKETFPKVWL
                     DEVESYSFDDIKLWGMKNYRAYLKHMYGDYMQLPPENQRNHHKRIKIDFGPYVEK"
     misc_feature    6646..7317
                     /gene="wcxR"
                     /locus_tag="SPC16A_0010"
                     /note="HMMPfam hit to PF04991, LICD Protein Family, score
                     5.1e-39"
     gene            7416..7880
                     /gene="wchJ"
                     /locus_tag="SPC16A_0011"
     CDS             7416..7880
                     /gene="wchJ"
                     /locus_tag="SPC16A_0011"
                     /note="member of homology group 26"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33437.1"
                     /db_xref="GOA:Q4K1H9"
                     /db_xref="InterPro:IPR013969"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H9"
                     /translation="MSKKEIKLCLVGSSGGHLNHLYLLKPFWQDKDRLWITFDKEDAR
                     SILSNEKCHYCYYPTNRNIKNLIKNTFLALRILYKERPDVIISSGAAVAIPFFYLGKI
                     FGAKTVYIEVFDRVDAPTMTGKIVYPVTDRFIVQWEEMKKIYPKAINLGGIF"
     gene            7880..8359
                     /gene="wchK"
                     /locus_tag="SPC16A_0012"
     CDS             7880..8359
                     /gene="wchK"
                     /locus_tag="SPC16A_0012"
                     /note="member of homology group 27"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33438.1"
                     /db_xref="GOA:Q4K1H8"
                     /db_xref="InterPro:IPR007235"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H8"
                     /translation="MIFVTVGTHEQQFNRLIKEIDELKAEGVITSDVFIQVGFSDYQP
                     RFCRWERFLSYDEMNNLMEEADIVITHGGPATFMNVIANGKRPVVVPRRKKFGEHVND
                     HQLDFCNRIVQEGYDLVVIEDIKKIREYLNPSSSIAVKSNNECFVQHFSNLIAELVE"
     misc_feature    7880..8350
                     /gene="wchK"
                     /locus_tag="SPC16A_0012"
                     /note="HMMPfam hit to PF04101, Glycosyltransferase family,
                     score 5.6e-45"
     gene            8352..9485
                     /gene="wcyK"
                     /locus_tag="SPC16A_0013"
     CDS             8352..9485
                     /gene="wcyK"
                     /locus_tag="SPC16A_0013"
                     /note="member of homology group 116"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33439.1"
                     /db_xref="GOA:Q4K1H7"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H7"
                     /translation="MSKNDEEHRRRHLMKILHIPTGGLFSDGIGTFIYSYLEYMDLSE
                     IEVTILATNKPLLEDKLKFQVLGVQIVEIERKKSSILAYMREFLELLKVGKYDVVHVH
                     GSSALMSIELFIAKIMGVPVRIAHSHNTTCNHILLDRMLRPFFYTLYTQSWACGEKAG
                     EWLFKDKRFKVIHNARDVEKYSFNPHLRRVFRTTHSLKENTLALGHVGRFNIQKNHTF
                     LLDLMDEMKCKQKDVKLFLVGEGEKVEDVKRYVKERKLEDSIVFLNRYSDMQSFISAM
                     DIMLLPSLYEGLPLVAIEWQINGIQSILSTTISDECIFTNSIQQLPIDNVSTWIKKAI
                     EDFSYINRLEKSRENIDLAQKSNYDIRIEAKKLEHEYKKLIGE"
     misc_feature    8913..9401
                     /gene="wcyK"
                     /locus_tag="SPC16A_0013"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.6e-08"
     gene            9493..10419
                     /gene="wcxS"
                     /locus_tag="SPC16A_0014"
     CDS             9493..10419
                     /gene="wcxS"
                     /locus_tag="SPC16A_0014"
                     /note="member of homology group 104"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33440.1"
                     /db_xref="GOA:Q4K1H6"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H6"
                     /translation="MNISIVLSTFNGDEYIVEQLDTLRNQTRLAEEVLISDDASTDDT
                     VQIIEDYIAKYKLDNWSIKKNKENQGWKNNFAMLLEEAKGDIVFLCDQDDIWHLDKIQ
                     KMSKIMENNDKILLLASNYTPFYVGDGVKIKLDKSDLDNSEAVYQPNFLDNFFHIRRP
                     GCVYAVNKKIIPYFLEIRSNEDAHDALLWRLASFLNGLYIYSYSTIDFRRHDSNATGS
                     RERSFLRRKEQVIYYDDLLQRLDKFSKQHDLSLSNEQISVLNDYILWGKNRRELFMKR
                     NVFIFFKLFKYHKLYWSFRSYITDFIVLYMKE"
     misc_feature    9502..10014
                     /gene="wcxS"
                     /locus_tag="SPC16A_0014"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1.7e-29"
     gene            10435..11640
                     /gene="wzy"
                     /locus_tag="SPC16A_0015"
     CDS             10435..11640
                     /gene="wzy"
                     /locus_tag="SPC16A_0015"
                     /note="member of homology group 152"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33441.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H5"
                     /translation="MLVKVKGGFKVSLSRVKTDVKLNEFLFGLAFYPWLIAWLFTSTF
                     YKDFIHPYGIIKTWEYVGLFFLLFKFMLGKSKIKSIIITPIILLIGFIVSYDNGNASF
                     VAYTLTLIYSSRDINFRNLVRNTMFCQIGVVGTVIVSSLLGIIPNELALTYSEGVIRS
                     RYGLGFHYTSFTPNYFLSILLEYVYLKGEKYWTIKELFICVLLNIVIYKYTDTRLTFI
                     MVFILLLISFSRRFVSINMNFKFLKYLLTLIYPIMAYMTYWLTAKFDSRNSLLSLINN
                     LLSQRLRFGQEGLRRYPLRLFGTHIQWDASANSYLYVDSSYINILISYGTIIFFLTLI
                     SYSIIMKKVIINQNKTLLIVLIFWSVRACIDPQLFLLWFNPFLFLIARTFLDEREEIG
                     DDITYMCIE"
     gene            11612..12340
                     /gene="wcxT"
                     /locus_tag="SPC16A_0016"
     CDS             11612..12340
                     /gene="wcxT"
                     /locus_tag="SPC16A_0016"
                     /note="member of homology group 153"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33442.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H4"
                     /translation="MISLICVSNNYDKLNTILKSSLSRQKDVNYELIIVDSNKYGFNS
                     AAEALNFGGKQAKGDYLFFVHQDISFQDDFELAKLESYCRNSIFGVAGVAGVKNIEGK
                     VVSFSNIFHGDPKTKAAGKSISAPVEVDAIDECLIIIPKKVFSTNQFSIIGPTWHLYG
                     TDYALQMKLINSPVLVFPSELWHVSDGKSLNLNYFDAIQWLLKKYSKNYSVIYTFFGV
                     WPSNPILLKFKCLYRKLRFYIKGV"
     gene            12340..13095
                     /gene="wciB"
                     /locus_tag="SPC16A_0017"
     CDS             12340..13095
                     /gene="wciB"
                     /locus_tag="SPC16A_0017"
                     /note="member of homology group 16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33443.1"
                     /db_xref="GOA:Q4K1H3"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H3"
                     /translation="MEVKLYVATHKSYNQVQDQDLYIPILVGADKNIGEKNYLRDNQG
                     DNNISDRNFTFCELTGLYWIWKNSKDDIVGLCHYRRYFGKNKRFLKQNSILKKNDILK
                     QLNDYDVILPSKSMNEYNGYTAEEFFNKNHDHKVWEMCRQIISENNKDYLDAFNWFSK
                     EKTGYCYNMFIMSREMMDEYCSWLFPILFELDKKIDYSRYDSYNTRMIGFVAERLINV
                     WVHKKQLTVKEFPVFSTEEPGFLQRIQKKLFNK"
     gene            13214..14629
                     /gene="wzx"
                     /locus_tag="SPC16A_0018"
     CDS             13214..14629
                     /gene="wzx"
                     /locus_tag="SPC16A_0018"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI33444.1"
                     /db_xref="GOA:Q4K1H2"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H2"
                     /translation="MKILKNYVYNLLYQILVVVLPIITTPYITRIFSSQELGDYGYYS
                     SIVTYFILLATLGVANYGTKVISGHRNEINKNFWGIYSLQLGATILSISLYCIFCVNL
                     PPMQNPVAYILGLSLVSKGLDISWLFQGLEDFRKITVRNITVKLIGVISIFLFVKSTN
                     DLYLYVFLLTIFELLGQLSMWLPARGFIGKPHVDLEYARYHLKPIILLFLPQIAISLY
                     VTLDRTMLGALSSTKDVGIYDQALKLVNILLTLVTSLGSVMLPRVANLLATGDHRAVN
                     KMHEMAFLIYNLVIFPIISGMLIVNDDFVQFFLGQDFQDARYAIAIMIFRMFFIGWTN
                     IMGIQILIPHNKNKEFMVSTTAPAIISVGLNLLFLPKLGYIGAAIVSVLTEALVWAIQ
                     LYFTRKYLKEVSIIGSMTKIILASAIMYGILLGSKTFIQFSPTINVLAFAVFGGLIYL
                     FAILSLKVVDVKELKQMIRKK"
     misc_feature    13220..14014
                     /gene="wzx"
                     /locus_tag="SPC16A_0018"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 4.3e-68"
     gene            14631..15629
                     /gene="wciG"
                     /locus_tag="SPC16A_0019"
     CDS             14631..15629
                     /gene="wciG"
                     /locus_tag="SPC16A_0019"
                     /note="member of homology group 21"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33445.1"
                     /db_xref="GOA:Q4K1H1"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H1"
                     /translation="MHKTRNINLELLKVLACVGVVLLHTTMGGFKEIGSWNLLTYLYY
                     LGTYSIPLFFMVNGYLLLGKREITYPYILHKVKWILITVLSWTLIVWFLKRDFTVNPV
                     KKLIGSLVQKGYFFQFWFFGSLILIYLCLPILKKILNSKRRYFYILSLLVVIGLIFEL
                     INYSLKMPVQFYIIQTFRLWTWLFYYLLGGFIAHFDIDIIKNRFKRWMKLVVVLLFLI
                     SPLILFFIAKTAYHNLFAEYFYDILFVKVVSLGIFLTILTLTLNEKRSECIVSLSNQT
                     MGVFIIHTYIMKIWEKLFGFSFVGSYLLFAIFTLSVSFIIVGMLMKIPYFNRIVKL"
     gene            15644..16744
                     /gene="glf"
                     /locus_tag="SPC16A_0020"
     CDS             15644..16744
                     /gene="glf"
                     /locus_tag="SPC16A_0020"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI33446.1"
                     /db_xref="GOA:Q4K1H0"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1H0"
                     /translation="MYDYLIIGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFVEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     misc_feature    16079..16681
                     /gene="glf"
                     /locus_tag="SPC16A_0020"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 5.3e-139"
     gene            16771..17640
                     /gene="rmlA"
                     /locus_tag="SPC16A_0021"
     CDS             16771..17640
                     /gene="rmlA"
                     /locus_tag="SPC16A_0021"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI33447.1"
                     /db_xref="GOA:Q4K1A5"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4K1A5"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    16774..17490
                     /gene="rmlA"
                     /locus_tag="SPC16A_0021"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 4.9e-120"
     gene            17641..18234
                     /gene="rmlC"
                     /locus_tag="SPC16A_0022"
     CDS             17641..18234
                     /gene="rmlC"
                     /locus_tag="SPC16A_0022"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI33448.1"
                     /db_xref="GOA:Q7BTQ6"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q7BTQ6"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     misc_feature    17677..18207
                     /gene="rmlC"
                     /locus_tag="SPC16A_0022"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 8.8e-16"
     gene            18247..19296
                     /gene="rmlB"
                     /locus_tag="SPC16A_0023"
     CDS             18247..19296
                     /gene="rmlB"
                     /locus_tag="SPC16A_0023"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI33449.1"
                     /db_xref="GOA:Q4K121"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K121"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    18262..19218
                     /gene="rmlB"
                     /locus_tag="SPC16A_0023"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 7.1e-05"
     misc_feature    18265..19005
                     /gene="rmlB"
                     /locus_tag="SPC16A_0023"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 2.7e-76"
     misc_feature    18265..19101
                     /gene="rmlB"
                     /locus_tag="SPC16A_0023"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0039"
     misc_feature    18268..19080
                     /gene="rmlB"
                     /locus_tag="SPC16A_0023"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.6e-05"
     gene            19362..20213
                     /gene="rmlD"
                     /locus_tag="SPC16A_0024"
     CDS             19362..20213
                     /gene="rmlD"
                     /locus_tag="SPC16A_0024"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI33450.1"
                     /db_xref="GOA:Q4K1G6"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1G6"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    19362..20210
                     /gene="rmlD"
                     /locus_tag="SPC16A_0024"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 4e-147"
     misc_feature    19365..19994
                     /gene="rmlD"
                     /locus_tag="SPC16A_0024"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.9e-19"
     misc_feature    19365..20006
                     /gene="rmlD"
                     /locus_tag="SPC16A_0024"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00013"
     misc_feature    19368..20096
                     /gene="rmlD"
                     /locus_tag="SPC16A_0024"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2.9e-08"
     gene            order(20276..20743,20861..21166,21228..21449)
                     /gene="glf"
                     /locus_tag="SPC16A_0025"
     CDS             join(20276..20743,20861..21166,21228..21449)
                     /gene="glf"
                     /locus_tag="SPC16A_0025"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI33451.1"
                     /db_xref="GOA:Q4K1G5"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1G5"
                     /translation="MYDYLVVGAVFAHEAALEGKKVKVIEKRNHIAGNIYTREEEGIQ
                     VHQYGAHIFHTSDKEIWDYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNKLWGVV
                     TPAEVQAKIDEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGQTNYMLDH
                     ENIDVETNVDFFVNKEQYLKDFPKIVFTGMIDEFFDYKLGELEYRSLRFENETLDMEN
                     YQGNAVVNYTDAETPYTRIIEHKHFEFGSQAKTIITNRTFLYKSYKKLADEQGNVIFG
                     GRLGHYRYYDMHQVIGAALQCVRNELDSYSMKIKEQTRKLAAGCSKHCFEVADGS"
     misc_feature    join(20696..20743,20861..21166,21228..21305)
                     /gene="glf"
                     /locus_tag="SPC16A_0025"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 9.6e-40"
     gene            21683..>21730
                     /gene="aliA"
                     /locus_tag="SPC16A_0026"
     CDS             21683..>21730
                     /gene="aliA"
                     /locus_tag="SPC16A_0026"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33452.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ89"
                     /translation="MMKSSKLLALAGVTLL"
BASE COUNT     7198 a   3163 c   4340 g   7029 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggatgactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attcttgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga agacgaacat
      301 aaagaagcgt atccttagtg caggcctgac ttttacatct gctttgcttt tagctgcttg
      361 cgaccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaactat ctattagact attacgctga taatatagtc aattgaaaca agagaaagac
      481 aaaagagcct cgtaaaaggt attgcaactt ggtaatacct ttttgaggtg ctttttgata
      541 tgagcccatg ttttctcaat aggattgtac tcaggcgagt agggaggaag atgtaaaagt
      601 tcatgcccaa actcttcaca caagagttct aacttaccca ttctatggaa tcttgcatta
      661 tccataataa caaccgatgg tgtggttaat gttggtaaga gaaatttctg aaaccaagct
      721 tcaaaaaagt cgctcgtcat cgtctcttcg taagtcattg gagcgattaa ctcaccattg
      781 gttagacctg caaccaaaga aatcctctga tatcttcttc cagatacttt gcctcttatt
      841 aactgacctt ttaatgagcg accatattct cgataaaaat aagtatcgaa tcctgtttcg
      901 tcaatctaaa caggtgctag gtgctttaaa ctattaaaat tcttaagaaa taaggctact
      961 ttttctgggt cttgttcata attagattga aactagaata gtacacctct acttctaaaa
     1021 cattgttaga aatcgatttg tcatgttctt atttcatttt actatatttt tgtttcgcgg
     1081 gaagtctact aagatactta aagatgcaga tagaagatgc agatagtaaa aaaaatgtag
     1141 acattaccgt aaaaaagtga tataatcgta tgatgttcaa ggtataggtg ttaatcatga
     1201 gtagacgttt taaaaaatca cgttcacaga aagtgaagcg aagtgttaat atcgttttgc
     1261 tgactattta tttattgtta gtttgttttt tattgttctt aatctttaag tacaatatcc
     1321 ttgcttttag atatcttaac ctagtggtaa ctgcgttagt cctactagtt gccttggtag
     1381 ggctactctt gattatctat aaaaaagctg aaaagtttac tatttttctg ttggtgttct
     1441 ctatccttgt cagctctgtg tcgctctttg cagtacagca gtttgttgga ctgaccaatc
     1501 gtttaaatgc gacttctaat tactcagaat attcaatcag tgtcgctgtt ttagcagata
     1561 gtgatatcga aaatgttacg caactgacga gtgtgacagc accgactggg actgataatg
     1621 aaaatattca aaaactacta gctgatatta agtcaagtca gaataccgat ttgacggtcg
     1681 accagagttc gtcttacttg gcagcttaca agagtttgat tgcaggggag actaaggcca
     1741 ttgtcttaaa tagtgtcttt gaaaatatca tcgagtcaga gtatccagac tacgcatcga
     1801 agataaaaaa gatttatacc aagggattca ctaaaaaagt agaagctcct aagacgtcta
     1861 agaatcagtc tttcaatatc tatgttagtg gaattgacac ctatggtcct attagttcgg
     1921 tgtcgcgatc agatgtcaat atcctgatga ctgtcaatcg agataccaag aaaatcctct
     1981 tgaccacaac gccacgtgat gcctatgtac caatcgcaga tggtggaaat aatcaaaaag
     2041 ataaattaac ccatgcgggc atttatggag ttgattcgtc cattcacacc ttagaaaatc
     2101 tctatggagt ggatatcaat tactatgtgc gattgaactt cacttctttc ttgaaaatga
     2161 ttgacttatt gggaggggta gatgttcata atgatcaaga gttttcagct ctacatggga
     2221 agttccattt cccagtaggg aatgtccatc tggactctga gcaggctcta ggttttgtac
     2281 gtgaacgcta ctcactagcc gatggagacc gtgaccgtgg tcgcaaccaa caaaagatca
     2341 ttgtagcaat tattcagaag ttaacttcta cagaggtttt gaaaaactat agtagtattc
     2401 ttcaaggatt gcaggattct cttcaaacaa atatgccgat tgagactatg atagatttag
     2461 tgaatactca gttggaaagt gaggggaatt ataaagtaaa ttctcaagat ttaaaaggga
     2521 caggtcggat ggatcttcct tcttatgcaa tgccagacag taacctctat gtgatggaaa
     2581 tagatgatag tagtttagct gtagttaaag cagctataca ggatgtgatg gagggtagat
     2641 gaaatgatag acattcattc gcatatcgtt tttgatgtag atgacggtcc caagtcaaga
     2701 gaggaaagca aggctctctt ggcagaatcc tacaggcagg gggtgcgaac cattgtctct
     2761 acctctcacc gtcgcaaggg catgtttgaa actccggaag agaagatagc agaaaacttt
     2821 cttcaggttc gggaaattgc aaaagaagta gcagatgatt tagtcattgc ttatggcgca
     2881 gagatatact atactctgga tgctctagaa aagctagaaa aaaaagaaat tcctaccctt
     2941 aatgatagtc gttatgcttt gattgagttt agcatgcata cttcctatcg tgagattcat
     3001 acgggattga gcaatatttt gatgttggga atcacgccag taattgctca tattgaacgt
     3061 tatgatgctt tagagaataa tgaaaaacgt gtttgtgaac tgattgatat ggggtgctat
     3121 actcagataa atagttatca tgttttaaaa cctaagttct ttggtgaaaa atataaattc
     3181 atgaaaaaga gagctcggta ttttttggaa cgtgatttag ttcatgtagt tgcaagtgac
     3241 atgcacaatt tagacagtag acctcctcat atggcagaag catatgacct tgttacccaa
     3301 aaatacggag aagcgaaggc tcaggaactt tttgtagata atcccagaaa aattataatg
     3361 gatcaattaa tttaggagaa aatatgaagg aacaaaacac tttggaaatc gatgtattgc
     3421 aactattcag aattttatgg aaaagaaagt tggtcatttt attagtggca attataactt
     3481 cttcagttgc ttttgcctac agtacttttg ttatcaaacc tgagtttact agtacgactc
     3541 ggatttatgt agttaaccgt aatcaggaag agaagtctgg tttaaccaat caagacttgc
     3601 aggcaggatc atacttggtt aaagactatc gtgaaattat cctatcgcag gatgttttgg
     3661 aggaagttat ttctgatttg aaattagatt tgacgccaaa aggtttggct aataaaatta
     3721 aagtaacagt accagttgat acccgtattg tctctgtttc agttaatgat cgagttcctg
     3781 aagaggcaag ccgtatcgct aactctttga gagaagtagc tgctcaaaaa attatcagta
     3841 ttactcgtgt ttctgatgtg acaacactgg aggaggcaag accggcgata tcaccatctt
     3901 cgccaaatat taaacgcaat acactaattg gttttttggc aggggggatt ggaactagtg
     3961 ttatagtttt tcttcttgaa cttttggaca ctcatgtgaa acgtccggaa gatatcgaag
     4021 atacactgca gatgacactt ttgggagttg taccaaactt gagtaagttg aaataggaga
     4081 gaggaatgcc gacattagaa atagcacaaa aaaaactgga gttcattaag aaggcagaag
     4141 aatattacaa tgccttgtgt acaaatatac agttgagcgg agataaacta aaagtaattt
     4201 ccgttacttc tgttaaccct ggggaaggaa aaacaactac ttccgtaaat atagcaaggt
     4261 cgtttgcgcg tgcaggctat aaaactcttt tgatcgatgg cgatactcga aattcagtta
     4321 tatcaggagt ttttaaatcg cgtgaaaaaa ttacagggct aacagaattt ttatctggga
     4381 cagctgattt atctcacggt ttatgtgata caaatattga aaatttattt gtaattcaat
     4441 cgggatctgt atcaccaaac cctacagcct tgttacaaag taaaaatttt aatgatatga
     4501 ttgaaacatt gcgtaaatat tttgcttata tcattgttga tacagcacct attggaattg
     4561 ttattgatgc ggcaattatc actcaaaagt gtgatgcgtc catcttggta acagcaacag
     4621 gtgaggtgaa taaacgtgat gtccaaaaag cgaaacaaca attagaacaa acagggaaac
     4681 tgttcctagg agttgtttta aataaattgg atatctcggt tgataagtat ggagtttacg
     4741 gttcctatgg aaattatggt aaaaaataac ttaggaaata ttttatggat gaaaaaggat
     4801 tgaaaatttt tctggcagta ttacagagta taattgtcat tttattggtt tattttctta
     4861 gctttgttag agagacagaa cttgaacgtt cttcgatggt tatactatac cttctccact
     4921 tttttgtatt ctattttagt tcctatggta acaatttttt taaaagaggg tacttagttg
     4981 agtttaatag tactataaga tatatttttt tctttgcaat agctataagt gtattaaact
     5041 tttttatagc ggaacggttt agtatctcta gaagaggaat ggtatacttc ttaactttag
     5101 aaggaatatc cttatacttg ttaaatttct tagtaaagaa atattggaag catgtgtttt
     5161 ttaatctaaa aaatagcaag aaaattttac tgttaacagt aacgaaaaat atggaaaaag
     5221 ttcttgataa attgctagaa tctgatgaac tttcatggaa attggtagca gtaagtgttt
     5281 tggataaatc tgattttcaa catgataaaa tacctgtaat tgaaaaggaa aaaattattg
     5341 aatttgcaac gcatgaagtt gtggatgagg tgtttgtcaa tcttccagga gagagctacg
     5401 atattggaga aattatctct aggtttgaga caatggggat agatgtaact gtaaatctta
     5461 aagcatttga taagaatttg ggtcgcaata aacaaattca tgagatggta ggattgaatg
     5521 tagtcacttt ctctacaaat ttttataaaa ttagtcatgt gatttcaaag agaattctcg
     5581 atatttgtgg tgccactatt ggccttgttc tttttgctat agctagtcta gttttagttc
     5641 cattgattcg taaagatggc ggaccagcta tttttgctca aactcgtata gggaaaaatg
     5701 gtcgacattt taccttttat aaattccgtt cgatgcggat cgatgctgaa gctatcaaag
     5761 aacaattgat ggatcaaaat acgatgcaag gtggtatgtt taagattgac aatgatcctc
     5821 gtgttacaaa aattggtcgc tttattcgta aaaccagttt ggatgaattg ccgcagtttt
     5881 ggaatgtctt tataggagat atgagtttgg tgggaacacg tccacctaca gtagacgagt
     5941 atgatcagta tactccagaa cagaaacgtc gactcagctt taaacctggt attacaggtt
     6001 tatggcaggt tagcggccgt agtaaaataa ccgattttga cgatgttgta aaattagatg
     6061 tggcttatat tgataattgg acaatctgga aagatattga aattttgcta aaaactgtta
     6121 aagttgtatt tataagagat ggagcgaagt aaataatgaa aaaagttata acatatggaa
     6181 catttgattt gttgcactat ggtcatatta atcttcttaa aagggctaaa tcgttaggcg
     6241 attatttaat tgttgtgatt tccactgacg aattcaactg gaatgaaaaa caaaaaaaat
     6301 gttattttac atatgaacaa agaaaaacac tcgtagaggc tgttaggtat gttgatttag
     6361 taatacctga agaatcatgg gaacaaaaag tgacagatgt ccatgaatat cacatagata
     6421 cctttgtcat gggagatgat tggaagggga aatttgattt tttagagaag gaaggagttg
     6481 aagtggtcta tttatcacgg actcctgaaa tcagtacaac tgaaattaag aattcattgg
     6541 caaccagaga atattaaaaa cggagtttaa gataaatata tgacagatga attagaacgg
     6601 ttacataact tagaactttt gttagcttca gaagtgttaa aaatatgtgg aaaatataat
     6661 ttaaaaatcg tgatgctagc aggaactttt ctaggggcta tacgccataa tggattcatc
     6721 ccgtgggacg atgatatgga ttttggtatg ccaagagagg attttgaaag atttaaagaa
     6781 ttatgtgttt cggatttgga cagggaaaaa tattttctac agacagatca aacagatttg
     6841 aattatccat ttaattttgt gaaactacgt ctcaataata cacatgtttc tgaggaattt
     6901 tctttagatg caaatgttca tgatggaatt tatattgata tttttccgat tgataatatc
     6961 tgtcccaagc cttttagacg attcattcaa cttaaaggat tttggttatt ccgaaatcta
     7021 ttatggataa aatgtggata tggggacaac gatagaaaaa aacgattagc gtataaacta
     7081 gctaagcttg ccacacatgt gttctcaata tcttttttga aaaagatgaa ggagaagtgt
     7141 atattactag ggcagagtac caatgctgat aatgtagtgg ttagtgatgg tagttatgga
     7201 ataaagaaag aaacttttcc aaaagtgtgg ttagacgaag ttgaaagtta ttcctttgat
     7261 gatataaaat tatggggaat gaagaattat agagcatact taaaacatat gtatggtgac
     7321 tatatgcagc ttccacctga gaatcaacga aatcatcaca aacgaattaa aattgatttt
     7381 ggcccatacg tggaaaaata ggagaattta taactttgtc taaaaaagag ataaaacttt
     7441 gtctagtagg atctagcggt gggcatttaa atcatctcta tctattgaaa ccattttggc
     7501 aggataaaga tagactatgg attacttttg ataaagaaga tgctcgaagt attttatcaa
     7561 atgaaaaatg tcattattgc tattatccga ctaatcgtaa tataaaaaat ctaataaaaa
     7621 atacatttct tgctttaaga atattatata aagaaaggcc agatgttatc atttcatccg
     7681 gagcagcggt tgcaataccg ttcttttatt taggtaaaat atttggtgct aaaactgttt
     7741 atatagaagt atttgatcgt gtagacgctc caacaatgac tggcaaaata gtataccctg
     7801 ttacagatag attcattgtc caatgggaag aaatgaaaaa aatctatccc aaggcaatca
     7861 atttgggagg aattttctaa tgatttttgt aactgtcggt acgcatgagc aacaatttaa
     7921 tagactaata aaagagattg atgaattgaa agcagaggga gttattacgt cggatgtatt
     7981 tatccaagtt ggtttttcag actatcaacc tcgattttgt agatgggaac gttttctttc
     8041 gtatgatgag atgaataacc taatggaaga agcggatata gttattactc atggtggtcc
     8101 tgctacattt atgaatgtta ttgctaatgg gaaaagacca gtagttgttc cgagaagaaa
     8161 aaaatttgga gaacatgtga atgaccatca gttagatttt tgtaatagga ttgttcagga
     8221 gggatatgat ttagtagtca tagaggatat taaaaaaatc cgagaatacc tgaatccatc
     8281 tagtagtatt gccgttaaat ctaataatga atgctttgta caacattttt caaatttgat
     8341 tgcagaatta gttgagtaaa aatgacgaag agcatagaag gagacacttg atgaaaattt
     8401 tgcatattcc aacaggaggt ttgttttctg atgggattgg aacatttata tattcatacc
     8461 tcgaatacat ggacttgagt gaaattgaag tgacgattct agctaccaat aaaccgttgt
     8521 tagaagataa attaaaattt caagtattag gtgttcagat tgtagaaatt gaaagaaaga
     8581 aatcctcaat actggcatat atgagagaat tccttgaact cttaaaagta ggaaaatacg
     8641 atgttgtaca tgttcacggg agtagtgctc ttatgtcaat tgaattgttt atagcaaaaa
     8701 ttatgggagt tcctgtaaga atagcgcata gtcataatac aacgtgtaat catattctac
     8761 tagacagaat gttacgtcct tttttttaca ctttatatac tcaatcttgg gcgtgtggtg
     8821 aaaaggcagg agaatggctt tttaaggata aacgatttaa agttatacat aatgccaggg
     8881 atgtagaaaa atatagtttt aatcctcatc ttcgccgagt atttcggaca acacattcat
     8941 taaaagaaaa tacacttgca ttaggacatg taggcagatt caatattcaa aaaaatcata
     9001 catttcttct ggatttaatg gatgaaatga aatgtaagca gaaggatgta aaattgtttt
     9061 tggtcggtga aggagaaaaa gtagaagatg ttaagagata tgtaaaagaa cgaaaattag
     9121 aagattcaat tgtttttttg aatcggtatt cggatatgca atcgtttatt tctgctatgg
     9181 atataatgtt attaccgagt ttatacgagg ggttaccttt agttgctatt gagtggcaaa
     9241 ttaatggaat tcaatctatt ctttcaacga caatttctga tgagtgcatc ttcacaaaca
     9301 gtatccaaca attaccaatt gacaacgtaa gtacttggat aaaaaaagct attgaagatt
     9361 tttcatatat aaacagattg gaaaaatcta gagaaaatat tgacctagct caaaaatcaa
     9421 actatgatat caggattgag gctaaaaaat tagagcatga gtataaaaag ttgattgggg
     9481 agtaagaata caatgaatat atcaattgta ttatcaacat ttaatggtga tgaatatatt
     9541 gttgaacagt tagatactct aagaaatcaa acgcgccttg ctgaggaagt cttgattagt
     9601 gatgatgcat ctacagatga tactgttcaa ataattgaag attatattgc taaatataag
     9661 ttggataatt ggtctataaa aaaaaataaa gagaatcaag gatggaagaa taattttgcc
     9721 atgttattag aggaggcgaa aggagatatc gtttttcttt gtgatcaaga tgatatttgg
     9781 catttagata aaattcaaaa aatgtctaag attatggaaa ataatgataa aattttgttg
     9841 ttagcctcta attacacacc tttttatgtt ggtgatggtg tcaagattaa attggataaa
     9901 agtgatttgg ataatagtga ggcagtgtat caaccaaatt ttttagataa cttctttcat
     9961 attagaaggc cagggtgtgt ttatgcggtg aacaaaaaga ttattccata ttttttagaa
    10021 atccgaagta acgaagatgc acatgatgcc ttgttatgga ggctagcttc gtttcttaat
    10081 gggttataca tttactccta ctctactata gattttagaa gacacgatag caacgcgact
    10141 ggtagcagag aaagaagttt cctaaggaga aaagagcaag ttatttatta tgatgatttg
    10201 cttcagagat tagataaatt tagtaaacaa catgatttat cactttcaaa tgaacaaatt
    10261 agtgttttga acgactacat tctatgggga aaaaatcgaa gagaattgtt tatgaaaagg
    10321 aatgtattta tattttttaa attatttaaa tatcataagt tgtattggtc gttcaggtca
    10381 tatattactg attttatagt gttatatatg aaggagtaat tctagtaatg aagagtgtta
    10441 gtgaaagtaa aggggggatt caaagtgagt ctatcaagag ttaaaactga tgtaaaattg
    10501 aatgagtttc tttttggatt agctttttat ccttggctaa tagcatggct gtttacttcg
    10561 accttttata aggattttat acatccttat ggaataataa aaacttggga gtatgtggga
    10621 ttattttttc tattatttaa atttatgtta ggtaaatcta agataaaatc gataatcatt
    10681 actccaatta tacttcttat aggttttatt gtaagttatg ataatggtaa cgcctccttt
    10741 gtagcatata ctttgactct tatatattct tcaagggata ttaattttcg taatttggta
    10801 aggaatacaa tgttctgcca gattggagtt gtaggaactg ttatagtaag ctctttactt
    10861 ggtattattc ctaacgagct agccttaaca tattcagaag gtgtgatccg ctcacggtat
    10921 ggactaggtt ttcactacac atcatttact ccgaattatt tcctgagtat attgctggaa
    10981 tatgtgtatt taaaaggtga aaaatattgg acaataaaag agctttttat ttgtgtacta
    11041 ttaaatatag ttatttataa atacacagat acccgtctta cttttattat ggtatttatc
    11101 cttcttttga tatcgttttc gagaagattt gtatcaatca atatgaattt taaatttcta
    11161 aaatatttac ttactcttat ttatccaatt atggcgtata tgacttattg gctgacagca
    11221 aaatttgata gtagaaatag tttattatct ttaataaata acttattgag tcaaaggttg
    11281 agattcggtc aagaaggttt aaggagatac cctctaagat tatttggaac tcatattcaa
    11341 tgggatgctt cggcgaattc ttatctttat gtagattcgt cgtacattaa tatacttata
    11401 agctatggaa caataatttt tttccttacg ttaataagct attcaattat aatgaaaaaa
    11461 gttataatta atcaaaataa aactttattg attgtgttaa ttttttggtc agtaagagct
    11521 tgtattgacc cacaattatt tttattgtgg ttcaatccat ttttgttttt aattgcgaga
    11581 acgtttttag atgaaagaga ggaaattgga gatgatatca cttatatgtg tatcgaataa
    11641 ttacgataag ttaaatacaa ttcttaaatc atctttatct agacaaaagg atgttaatta
    11701 tgaacttatt atagtggatt ctaataaata tggatttaat tctgctgctg aggctttgaa
    11761 ttttggaggc aaacaagcaa aaggtgatta tctatttttt gttcatcaag atattagttt
    11821 tcaagatgac tttgagttag caaaactaga atcttattgt agaaattcca tatttggagt
    11881 agcaggagta gcaggggtaa agaatattga gggaaaggtc gtcagttttt caaatatttt
    11941 tcatggggac ccgaaaacaa aggcggctgg taaatctata agtgcccctg ttgaagttga
    12001 cgcaattgat gagtgtttga ttattattcc gaaaaaagtt tttagtacaa atcaatttag
    12061 tataatcggt cctacctggc atttatatgg aacagactat gcattacaga tgaagttaat
    12121 caattcgcca gtattagttt ttccaagtga gttatggcat gtgtcagatg ggaaatcttt
    12181 aaaccttaat tattttgatg cgatacaatg gttattgaaa aaatactcta aaaattattc
    12241 agtaatatac actttttttg gagtttggcc aagtaatcct attctattaa aatttaaatg
    12301 tctttatagg aaattaaggt tttatattaa gggagtgtaa tggaagtgaa gctatacgtc
    12361 gcaacacata aatcttataa tcaagttcaa gaccaggacc tatatatccc tatattggtg
    12421 ggcgcggata agaatattgg agaaaagaat tatttaagag ataatcaggg agataataat
    12481 atttctgata gaaactttac attttgtgaa ttaacaggat tgtattggat ttggaaaaat
    12541 tctaaagatg atattgttgg tttatgccat tatagacgtt attttgggaa aaacaagcgt
    12601 tttttaaaac agaattctat tttaaaaaag aatgatattc taaaacaatt aaatgattat
    12661 gatgtaatat taccatcaaa gagtatgaac gagtataacg ggtatactgc tgaagagttt
    12721 tttaacaaga atcacgatca taaagtttgg gaaatgtgta gacagattat ttcagaaaac
    12781 aataaagatt accttgatgc ttttaattgg ttttctaaag aaaaaacagg atactgttat
    12841 aatatgttta taatgtctag agaaatgatg gatgaatatt gcagttggtt atttccgatt
    12901 ctttttgaac tagataagaa gattgattat tcaagatatg atagttacaa tactcgtatg
    12961 attggttttg ttgccgaacg tttaattaac gtatgggtac ataagaaaca actaactgta
    13021 aaagagtttc cggttttttc aacagaagaa ccaggattct tacaaagaat tcagaagaaa
    13081 ttatttaata agtagtagtt tatttataaa agtagattgt taataaatct ttcaaggtgc
    13141 tattcccctt ttccaattaa gttttattgc acggtcctca taaatactcc tagaaagact
    13201 aagttaatta aagatgaaga ttttaaagaa ttatgtttat aatttgttat accagatact
    13261 agtagttgtt ctcccaataa taactactcc ctatattact agaatcttta gttctcaaga
    13321 gttaggtgat tatggatatt atagttctat agtaacttac tttatattgc tcgctacttt
    13381 aggtgtcgcc aactatggga ctaaggtaat ttctggacat cgtaatgaga ttaataaaaa
    13441 tttttggggt atctactctt tacaattagg tgctacaatc ctttcaatct ccttatattg
    13501 tattttttgc gttaaccttc ctccaatgca aaacccagta gcctatattt tgggattgag
    13561 tttagtttct aaaggtttag atatttcctg gctttttcaa ggattagagg atttccgtaa
    13621 aattactgtt cgaaatatta cggtaaaact aattggggta atctctattt tcctgtttgt
    13681 caaatctact aacgaccttt acctttatgt gttcttatta acaatatttg agctattggg
    13741 acaattaagt atgtggttgc cggcccgagg gtttattggt aagccccatg ttgatttaga
    13801 atacgctagg taccatttga aaccaattat tttattattt cttcctcaga tagcaatctc
    13861 tttatacgtt actttagatc gtacgatgct tggtgcttta tcctctacaa aagatgtagg
    13921 aatttatgat caggctctta aattggtaaa tattttatta acattggtaa catcgcttgg
    13981 aagtgttatg ttgcctcgag tagctaactt attagcaaca ggagatcata gagcagtcaa
    14041 taagatgcat gagatggctt tcttgattta taatttagtt atttttccta ttatatccgg
    14101 aatgttaatt gtcaatgatg attttgttca atttttcctt ggtcaagatt ttcaggatgc
    14161 acgttatgca atcgccatta tgattttccg tatgttcttt ataggttgga ccaatattat
    14221 gggaattcaa attttgattc cacacaataa aaataaggaa tttatggttt caacaacagc
    14281 tcccgcaatt atcagtgtag gtttgaacct gctattcctt cctaaacttg gttatatcgg
    14341 agcagctatt gtctctgttt taacagaagc gctagtatgg gcaattcaat tgtactttac
    14401 ccgcaaatac ctaaaggaag tttcaattat tggatctatg acaaaaatta ttctagcatc
    14461 agctatcatg tatggtattt tgcttggttc aaaaacattt atacagtttt caccaaccat
    14521 aaatgttcta gcatttgctg tgtttggtgg actcatttat ctttttgcaa ttctatctct
    14581 gaaagtggta gatgtaaaag aattaaaaca aatgattagg aaaaaataga atgcataaaa
    14641 ctcggaatat taatttagaa ctattaaaag tacttgcatg tgttggagtt gttctacttc
    14701 atacaacgat gggtgggttt aaagagatag gttcatggaa tcttttgaca tatttatatt
    14761 acttaggaac ctattctatc cctctatttt ttatggttaa tggttattta ttgttaggaa
    14821 agagagagat aacatatccc tatatactgc ataaagtaaa atggattcta ataacagtgt
    14881 tgtcatggac ccttatcgtt tggtttttaa aacgggattt tacagttaat ccagttaaaa
    14941 aacttatagg ctcgttggtg caaaaaggtt atttctttca gttttggttt tttggttcgc
    15001 ttatacttat ttatttatgt ctacccattt tgaaaaaaat tcttaattca aaaagaagat
    15061 atttttatat tctatcttta ttggtagtta ttggtttgat ttttgaactg ataaattact
    15121 cacttaaaat gccagtgcag ttttatatta tacaaacatt tagattatgg acttggcttt
    15181 tctattatct tttaggtggt tttatagctc actttgatat agatattatc aaaaataggt
    15241 ttaagagatg gatgaaatta gttgtagtac ttttattctt gatttcgcct ttaatattat
    15301 ttttcatagc gaagactgca taccataatc tttttgctga atatttttat gatattttat
    15361 ttgtaaaagt tgtaagcttg ggaatttttc taactatcct cacgcttact ttgaatgaaa
    15421 aacggagcga atgtattgtt tccctttcta atcaaaccat gggagttttt ataatacaca
    15481 catatattat gaagatatgg gaaaagctat ttggttttag tttcgtagga tcatatttac
    15541 tttttgctat atttacttta agtgttagtt ttattattgt tggaatgtta atgaaaattc
    15601 cttatttcaa tcgaatcgtt aaattataaa taggagattt aatatgtacg actatttaat
    15661 catcggagct ggtttgtctg gagcaatctt cgcacacgaa gctacaaaac gtggtaaaaa
    15721 agtaaaagtg attgataaac gcgatcacat tggagggaac atctactgtg agaatgtaga
    15781 aggtatcaat gttcataaat atggtgccca tatcttccat acgtcaaata aaaaagtctg
    15841 ggactatgtc aatcaatttg tagagtttaa caactatatc aactcacctg tcgcaaacta
    15901 taagggaagt ctttataacc ttcctttcaa tatgaatacc ttctatgcta tgtggggcac
    15961 aaaaactcca caagaagtga aggataagat tgctgagcag acagctggta tgaaggatgt
    16021 tgagccgaaa aatctggaag aacaagctat caagttgatt ggtccggata tctatgaaaa
    16081 gttgatcaag ggttatacag aaaagcaatg gggacgctca gcgacagaac ttcctccatt
    16141 tatcataaaa cgccttccag ttcgtttaac ctttgataat aactatttta atgaccgtta
    16201 ccaagggatt cctattggtg gttacaatgt catcatcgaa aatatgctga aagatgtaga
    16261 agttgaactt ggagtagact tttttgctca tcgtgaagag ttggaagcat ctgctaacaa
    16321 agttgtcttc acaggaatga tcgaccaata ttttgactac aagcacggag agttagaata
    16381 ccgtagcctt cgttttgagc atgagatttt agacgaggaa aattatcaag ggaatgctgt
    16441 agtgaactat acagagcgtg agatccctta tactcgtatc atcgaacaca aacattttga
    16501 atatggaatg cagccaaaga cagttatcac gcatgaatat ccagctgact ggaagcgtgg
    16561 ggacgagccc tactatccta ttaacgatga gaaaaataat gctatgtttg ctaaatacca
    16621 agaagaagca gcgcagaatg ataaagttat cttttgtggg cgtttagcag attataaata
    16681 ttacgatatg catgtggtga ttgaacgggc gcttgaggtt gtggagaaag aatttagtaa
    16741 ttgaaaaaca acgaagaaag gttgcttatt atgaaaggta ttattctagc aggtggttcg
    16801 gggacacgtt tatatccttt gactcgcgct gcatcaaaac aacttatgcc ggtttatgat
    16861 aaaccgatga tttactaccc actttcaaca ttgatgttgg ctgggattag ggatattttg
    16921 attatttcca ctccacagga tttacatcga tttcaagagc ttcttcaaga cggatctgag
    16981 tttgggatca aactttctta tgcagagcaa ccaagtccag atggtttggc acaagccttt
    17041 atcatcgggg aagagtttat ttctgatgat agcgttgcgc taatcttagg tgataatatc
    17101 taccatggtt ctgggctttc caagatgcta caaaaggcag cgagtaagga gtcgggagca
    17161 actgtttttg gctaccatgt caaggatcca gagcgctttg gtgtggttga gtttgatcag
    17221 gatatgaagg ctatttctat tgaagaaaag ccagagcaac ctcgttcaaa ctatgcagtt
    17281 acaggtctct atttctatga taatgatgta gtagagattg ccaagagtat taaaccaagt
    17341 cctcgtggtg aactggaaat tacagatgta aacaaagctt acctagatcg tggtgatttg
    17401 tctgttgagc tcatgggacg tggctttgct tggctggata ctggaactca tgaaagttta
    17461 ctagaggctt cacagtacat cgaaacagtg caacggatgc aaaatgttca ggtagcaaac
    17521 ttagaagaaa ttgcctatcg catgggttat atcagtcgtg aagatgtatt gaccttagcc
    17581 caaccactta agaaaaatga atacggacag tatctgctcc gtttgattgg agaagcatag
    17641 atgacagata attttttcgg taagacgctt gcggcacgca aggttgaagc tattccaggc
    17701 atgttggagt ttgatatccc cgttcatgga gataatcgtg gctggtttaa agaaaatttc
    17761 caaaaggaaa aaatgcttcc acttggattt ccagagtctt tctttgcaga aggaaaattg
    17821 caaaacaatg tatccttctc acgtaaaaat gtccttcgag gactccacgc agagccttgg
    17881 gataagtaca tctctgtagc agatggaggg aaagttctgg gttcttgggt tgatctacgc
    17941 gagggtgaaa cctttgggaa tacctatcag acagtaattg atgcaagcaa gggaatcttt
    18001 gttcctcgag gcgtagctaa tggcttccaa gttctatcag atacagtgtc atatagctat
    18061 ctggtcaatg attactgggc tctcgagctc aaacccaagt atgcctttgt gaactacgct
    18121 gatccaagcc ttggtattga atgggaaaat attgcagaag cagaggtttc agaagcagat
    18181 aaacatcatc ccctacttaa ggatgtaaaa cctttgaaaa aagaagattt gtaaaaagga
    18241 aagaatatga ctgaatacaa aaatattatc gtgacaggtg gagctggctt tatcggttct
    18301 aactttgtcc attatgttta cgagaacttt ccaggtgttc acgtgacagt cctagataag
    18361 ttgacttatg ctggaaatcg cgcgaatatt gaggaaattt taggtaatcg tgttgagtta
    18421 gttgttggtg acattgctga tgcggagttg gtagacaagt tggctgctca agcagatgct
    18481 atcgttcatt atgcagcgga aagccacaat gataattcgc tcaatgatcc atcgccattt
    18541 attcatacta acttcatcgg aacctatact cttttagaag ctgctcgtaa gtatgatatt
    18601 cgcttccacc atgtatcgac agatgaagtt tatggggatc tccctttacg cgaagatttg
    18661 ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg aaacaaaata caacccaagc
    18721 tctccgtact catcaaccaa ggcagcctca gatttgattg tcaaagcctg ggtgcgttct
    18781 tttggagtca aggcaacgat ttccaactgt tcaaataact acggtcctta tcaacatatc
    18841 gaaaaattca tcccacgtca gattactaac atcctaagtg gaattaagcc aaaactttac
    18901 ggtgaaggta agaatgttcg tgactggatt cataccaatg accattcttc aggagtttgg
    18961 acaatcttga caaaagggca aatcggtgaa acctacttga ttggggctga tggtgagaag
    19021 aacaataagg aagttttgga acttatcctt aaggaaatgg gacaagctac ggatgcctat
    19081 gatcatgtga ctgaccgtgc aggacatgac cttcgctatg cgattgatgc cagcaagctc
    19141 cgtgatgagt tggggtggaa acctgaattt accaactttg aagctgggct caaggcaaca
    19201 atcaagtggt atacagataa ccaagaatgg tggaaagcag aaaaagaagc tgttgaagcc
    19261 aattatgcta agactcagga gattattaca gtataaaaag caggaaatag ctgcttttta
    19321 ttgctatatt gggaagagtt acatattaga aaggtctaga gatgatttta attacagggg
    19381 caaatggcca attaggaacg gaacttcgct atttattgga tgaacgtaat gaagaatacg
    19441 tggcagtaga tgtggctgag atggacatta ccaatgaaga aatggttgag aaagtttttg
    19501 aagaggtgaa accgacttta gtctaccact gtgcagccta caccgctgtt gatgcagcag
    19561 aggatgaagg aaaagagttg gacttcgcca tcaatgtgac ggggacaaaa aatgtcgcaa
    19621 aagcatctga aaagcatggt gcaactctag tttatatttc tacggactat gtctttgacg
    19681 gtaaaaaacc agttggacaa gagtgggaag ttgatgaccg accagatcca cagacagaat
    19741 atggacgcac taagcgtatg ggggaagagt tagttgagaa gcatgtgtct aatttctata
    19801 ttatccgtac tgcctgggta tttggaaatt atggcaaaaa cttcgttttt accatgcaaa
    19861 atcttgcgaa aactcataag actttaacag ttgtaaatga ccagtacggt cgtccgactt
    19921 ggactcgtac cttggctgag ttcatgacct acctagctga aaatcgtaag gaatttggtt
    19981 attatcattt gtcaaatgat gcgacagaag acacaacatg gtatgatttt gcagttgaaa
    20041 ttttgaaaga tacagatgtc gaagtcaagc cagtagattc cagtcaattt ccagccaaag
    20101 ctaaacgtcc gctaaactca acgatgagcc tggccaaagc caaagctact ggatttgtca
    20161 ttccaacttg gcaagatgca ttgcaagaat tttacaaaca agaagtgaga taagtagtag
    20221 aatgattttc tagtctaata aaagagacag ataatgaact ccaaaggagc ttaagatgta
    20281 cgattatctt gttgttggtg cagtctttgc ccatgaagca gccttagaag gaaaaaaagt
    20341 aaaagttatt gaaaaacgaa atcatatcgc gggtaatatc tatactcgtg aagaggaagg
    20401 aattcaagtt catcaatatg gtgctcatat cttccatact tctgataagg agatctggga
    20461 ttatgtaaat cagtttgcag agtttaaccg ttataccaat tctcctgttg caaactataa
    20521 gggtgagatt tataaccttc cttttaatat gaataccttc aataaactct ggggagttgt
    20581 aacgccagca gaagtacagg ctaagattga tgaacaacgt gctattttaa atggtaaaac
    20641 tcctgaaaat ttggaagaac aggcgatttc tcttgtaggt acagacatct acgaaaaatt
    20701 aatcaaagac tatacagaga aacagtgggg gcaaaccaac tactgaactt ccatccttta
    20761 ttattcgctg tttaccagta cacctgacct atgataacaa ctattttaac gatacctatc
    20821 aagggattcc aattggtgga tacactcaaa tagttgaaaa atgttggatc atgaaaatat
    20881 tgatgtagaa acaaatgttg atttctttgt gaacaaagag caatatctga aagattttcc
    20941 taagattgtc tttactggta tgattgatga attctttgac tataagttgg gcgaactaga
    21001 gtaccgtagt cttcgttttg aaaatgagac cttggatatg gaaaattacc aaggaaatgc
    21061 agttgtgaac tatacggatg cagaaacccc atatactcgc attattgaac acaaacattt
    21121 tgagtttggg agtcaagcaa agactatcat tactaataga acattctaaa acatgggaaa
    21181 aaggtgatga gccttattat ccagttaata atgatcgtaa taatcatttg tataaatcat
    21241 ataaaaaact tgctgatgag caagggaatg ttatctttgg tggccgctta ggacactatc
    21301 gttattacga tatgcaccaa gtaattggag cagctttgca gtgcgtgaga aatgagttag
    21361 attcatactc aatgaaaatt aaagagcaaa ctaggaagct agccgcaggt tgctcaaagc
    21421 actgttttga ggttgcagat ggaagctgac gcggtttgaa gagattttcg acgagtataa
    21481 acaagtaaaa ctgactacca gttattattt agaaatagta ttaaaaattc cttgactata
    21541 tgatatagtt gagggatttt taaatgatat tcatattttt tgcaaagatg ttgtttgaaa
    21601 aataattttc aaaaattctg aaaattctgt tgacaacttt ctgaaaagag tctataatgg
    21661 agagaaagtt ttaaaggaga aaatgatgaa aagttcaaaa ctacttgccc ttgcgggcgt
    21721 gacattattg
//
