LOCUS       CR931669               23198 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain nr. 4704 (serotype 17a).
ACCESSION   CR931669
VERSION     CR931669.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23198)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 23198)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..23198
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="nr. 4704"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC17A_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC17A_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI33477.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            complement(262..453)
                     /gene="tnp"
                     /locus_tag="SPC17A_0002"
                     /pseudo
     CDS             complement(262..453)
                     /gene="tnp"
                     /locus_tag="SPC17A_0002"
                     /note="Lone member of homology group 0235"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
                     /db_xref="PSEUDO:CAI33478.1"
     gene            695..2140
                     /gene="wzg"
                     /locus_tag="SPC17A_0003"
     CDS             695..2140
                     /gene="wzg"
                     /locus_tag="SPC17A_0003"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33479.1"
                     /db_xref="GOA:Q4K1E2"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K1E2"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKRILLTTTPRDSYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQAIGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    695..811
                     /gene="wzg"
                     /locus_tag="SPC17A_0003"
                     /note="Signal peptide predicted for SPC0817 by SignalP 2.0
                     HMM (Signal peptide probability 0.997) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    899..1246
                     /gene="wzg"
                     /locus_tag="SPC17A_0003"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 3.7e-63"
     misc_feature    1424..1867
                     /gene="wzg"
                     /locus_tag="SPC17A_0003"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 2.3e-67"
     gene            2142..2873
                     /gene="wzh"
                     /locus_tag="SPC17A_0004"
     CDS             2142..2873
                     /gene="wzh"
                     /locus_tag="SPC17A_0004"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33480.1"
                     /db_xref="GOA:Q4JZG9"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZG9"
                     /translation="MIDIHSHIVFDVDDGPKSREESKTLLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMHTSYREIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRVQYFLEQDLVHVIASDMHNLDSRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRRIVMDQLI"
     misc_feature    2145..2753
                     /gene="wzh"
                     /locus_tag="SPC17A_0004"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1.4e-38"
     gene            2879..3574
                     /gene="wzd"
                     /locus_tag="SPC17A_0005"
     CDS             2879..3574
                     /gene="wzd"
                     /locus_tag="SPC17A_0005"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33481.1"
                     /db_xref="GOA:Q4K1E0"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K1E0"
                     /translation="MMKEQNTTEIDVFQLVKTLWKRKLMILLVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGSYLVKDYREIVLSQDVLEKVVTNLKL
                     DMPAKTLASKVQVTVPADTRIVSISVKDKQPEEASRIANFLREVAAEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKI
                     PLLGLVPDFDKIK"
     misc_feature    2879..2995
                     /gene="wzd"
                     /locus_tag="SPC17A_0005"
                     /note="Signal peptide predicted for SPC0819 by SignalP 2.0
                     HMM (Signal peptide probability 0.614) with cleavage site
                     probability 0.407 between residues 39 and 40"
     misc_feature    2900..3316
                     /gene="wzd"
                     /locus_tag="SPC17A_0005"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 5.5e-54"
     misc_feature    3422..3499
                     /gene="wzd"
                     /locus_tag="SPC17A_0005"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            3584..4273
                     /gene="wze"
                     /locus_tag="SPC17A_0006"
     CDS             3584..4273
                     /gene="wze"
                     /locus_tag="SPC17A_0006"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33482.1"
                     /db_xref="GOA:Q4JZK1"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZK1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSANIAWAFARAGYKTLLIDGDIRNSVMLGVFKARNKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRNCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            4288..5655
                     /gene="wchA"
                     /locus_tag="SPC17A_0007"
     CDS             4288..5655
                     /gene="wchA"
                     /locus_tag="SPC17A_0007"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33483.1"
                     /db_xref="GOA:Q4K1D8"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D8"
                     /translation="MNGKILRSSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELIQTLKYILFFALAISISNFFLEDQFSISRRGMIYF
                     LTLHALLVYGLNLFIKWYWKRAYPNFKGSKKILLLTATFRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFVTNEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRRFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     misc_feature    4288..4374
                     /gene="wchA"
                     /locus_tag="SPC17A_0007"
                     /note="Signal peptide predicted for SPC0821 by SignalP 2.0
                     HMM (Signal peptide probability 0.844) with cleavage site
                     probability 0.429 between residues 29 and 30"
     misc_feature    5071..5652
                     /gene="wchA"
                     /locus_tag="SPC17A_0007"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 3.3e-157"
     gene            5642..6448
                     /gene="wciB"
                     /locus_tag="SPC17A_0008"
     CDS             5642..6448
                     /gene="wciB"
                     /locus_tag="SPC17A_0008"
                     /note="member of homology group 16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33484.1"
                     /db_xref="GOA:Q4K1D7"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D7"
                     /translation="MERSRLIDVKIIVATHKEVKMPQDSSLYLPIHVGRDGKSDIGFI
                     GDNTGDNISSLNPYYCELTGLYWAWKNLDYNYLGLVHYRRYFTNKSQGYNENINMDDV
                     ILSRSNVEILLEKSDIIVPKKRKYYIETLYSHYAHTLNGEHLDLARKIIEQNSSEYLS
                     SFDKVMKQRSGYMFNMFIMKKELLDDYLPWLFSILDTMYEQMDLTDYTPFESRLFGRV
                     SELLFNVWLCKKGITPKEVPFMYMERVDLFEKGKSFLMAKFFGKKYGQSF"
     gene            6432..7529
                     /gene="wcrP"
                     /locus_tag="SPC17A_0009"
     CDS             6432..7529
                     /gene="wcrP"
                     /locus_tag="SPC17A_0009"
                     /note="member of homology group 89"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33485.1"
                     /db_xref="GOA:Q4K1D6"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D6"
                     /translation="MDRVFEMLEKESPLFSVIVPTYKISESNLRQCIDSLLYDSQDVE
                     IILVDDNKNLDICGKVLDEYAEKYNNISVIHQENQGVSVARNAGMSIAVGKYLIFVDP
                     DDWVAENFYSQMTLAVQKNPSSDVIILAAIVDYNGKQFTNHFWHTSRSFQGTDKDDLE
                     LQLIAKGATSYFPTEIGVGVPWAKIYRNEFVRENGLDFNPSLRRMQDNIFNMYAFEFA
                     NEIVYIDEPIYYYRKSMDSVTNKKNDKVIYYFDLVNDEVEKFIQKFNKPKIFEDALHI
                     KRLIGINSYYKLYFKFASTSSEKKKMRQEFRELLEREEYVNSLKKVNTAYLLPKEKIF
                     ISILKQKDLRIFSLLQKLEKLSVMLKSRQFS"
     misc_feature    6477..7016
                     /gene="wcrP"
                     /locus_tag="SPC17A_0009"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1.6e-30"
     gene            7537..8454
                     /gene="wcrQ"
                     /locus_tag="SPC17A_0010"
     CDS             7537..8454
                     /gene="wcrQ"
                     /locus_tag="SPC17A_0010"
                     /note="member of homology group 106"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33486.1"
                     /db_xref="GOA:Q4K1D5"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D5"
                     /translation="MRQLALELVSIIYKVTKRIPISFISNLGEKIYSFKDPYVFNVLS
                     TLGVDKESAYDLIPPNLFLNKIWICWFQGEDKAPDLVKKCIDSVRKHASGYDVIILTE
                     GNIEEYVTLPNIVLIKYKNGLFSRTHFSDIVRMNLLAQQGGLWIDATIFVTRDLDLSI
                     FFKNDFVSLRTTMKSSPLFITGYWTTYFVYTPSNFKLVQYTALLLNKYTEKYDRFIDY
                     FLQDYIITKAIKDLNYESYMEERPVLGNQRWLLADLANKVMTSDLLQQFKQDTVGIYK
                     LTYKSKYIREKNGRETVYKKIVEDGEYLE"
     misc_feature    7588..8427
                     /gene="wcrQ"
                     /locus_tag="SPC17A_0010"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 1.3e-45"
     gene            8435..9334
                     /gene="wcrR"
                     /locus_tag="SPC17A_0011"
     CDS             8435..9334
                     /gene="wcrR"
                     /locus_tag="SPC17A_0011"
                     /note="member of homology group 90"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33487.1"
                     /db_xref="GOA:Q4K1D4"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D4"
                     /translation="MENILNKKIGIVILNYLNWEDTLDCISSLRLQSNQNFEAVIVEN
                     GSPNESVSRIRDFIKNDKNIHLYVVENNLGYANGNNMGILYLKNKYSINRIILTNNDV
                     IFDDKNYISKLIDIEYDGNIGAIGTKIIGSDGLNQNPAYFPISFSSSIKSLIINLLAF
                     SKVIASIKKRFLSSWAKKANDFSSPKTSKQKYFLHGSVIFLTENYLDKFMGLYGGTFL
                     YYEEVILGIIFEKAGLDMLYIPEFSIYHKEDQSSIRSFNNDDLVRRRYLLNSIWSSFK
                     VYLANQEELPNIVSDSIYKHIKE"
     misc_feature    8462..8962
                     /gene="wcrR"
                     /locus_tag="SPC17A_0011"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 4.3e-13"
     gene            9343..10443
                     /gene="wcrT"
                     /locus_tag="SPC17A_0012"
     CDS             9343..10443
                     /gene="wcrT"
                     /locus_tag="SPC17A_0012"
                     /note="member of homology group 157"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAI33488.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D3"
                     /translation="MVKKIAFYLPQFHTIPENDKWWGKDFTEWTNVKKSQPQYRGHIQ
                     PEVPLNEEYYNLLDTEVQEKQAKLALEYGIDGFCYYHYWFDGKLLLEKPMENMLQNEN
                     ITLPFCICWANESWSRTWDGAESKVLIMQNYSDTLDGWKRHFDYLLPFFKDERYIKVD
                     EKPMMIIYKPQLIENLEEMTVYWNQLAKQNGFKGIHFGHQHVSSFEDSKVIENFDFGI
                     EFEPIYTVSEMHKSTRSKSEKLKRAIKNPKWFSRNISHKYFGRSLLFDYDEVWSAILR
                     REGRKNISPGAFVSWDNTPRRGNRSLVFDGANPKKFEKYFAKQVQRAKEEYHSDFIFI
                     NAWNEWAEGAHLEPDEQYGYGYLEAVRAVKEE"
     gene            10445..11071
                     /gene="wcrU"
                     /locus_tag="SPC17A_0013"
     CDS             10445..11071
                     /gene="wcrU"
                     /locus_tag="SPC17A_0013"
                     /note="member of homology group 158"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33489.1"
                     /db_xref="GOA:Q4K1D2"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="InterPro:IPR018357"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D2"
                     /translation="MLIGRLKQRLKIEKFRRSWREKNTHNTTMASSIFDIDKVSVGNY
                     TYGNIDILDFGTNEKLSIGSFCSIAPNVKFILNADHCTNYFTTFPLKVKVLQNQDKEG
                     ISKGDIIVGDDVWLGLNAVILSGVTIGQGAIIAAGAVVTKNVPPYAIVGGNPARIIKY
                     RFEAEIIDKLLKVNFSKLSKYDIEKHIKQMYIPLVEVKQLDWIDDLLH"
     misc_feature    10763..10816
                     /gene="wcrU"
                     /locus_tag="SPC17A_0013"
                     /note="HMMPfam hit to PF00132, no description, score 29"
     misc_feature    10790..10876
                     /gene="wcrU"
                     /locus_tag="SPC17A_0013"
                     /note="PS00101 Hexapeptide-repeat containing-transferases
                     signature."
     misc_feature    10817..10870
                     /gene="wcrU"
                     /locus_tag="SPC17A_0013"
                     /note="HMMPfam hit to PF00132, no description, score 0.93"
     gene            11084..13039
                     /gene="wcrV"
                     /locus_tag="SPC17A_0014"
     CDS             11084..13039
                     /gene="wcrV"
                     /locus_tag="SPC17A_0014"
                     /note="member of homology group 159"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33490.1"
                     /db_xref="GOA:Q4K1D1"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D1"
                     /translation="MKSEIKVSVVIPIYNQEIYLRKSIHSVLTQSYQNLEIIAVNDGS
                     IDSSQQIMEEFANQDSRIFLYEKSNGGLVDATIYGVEKATGDYIVFLDPDDYIGENYI
                     QKFVSYLDHDYDFVAMGFYYDDNDKVTPYRLKENLILNKTHIEVLKSTFLTNFDLGTI
                     SNQIFISRWNKLYRCDIVKSVISEFKSYKNVTLGEDTIFAALLLKYSQSAKILQQANT
                     YFYNIANQNSMMKSSDLDKYLNKCYQVFMSFSKLLEEQELDKTQAYYLYFFLTNTLFN
                     RLRTNDPKQFYGLFDKLKREPVYIKTLNMVRKNTKSKFISFDLFLRLYTTCSQYIYIK
                     DSIERTKTFVRNFKYFSRQVRKNNIIKAYQLLNFFRSRQNAFYELKNQLPKIEGEINN
                     ILLQHDSNEFNEEEGIEEKIFVFWWDGFNDLPEIVAECFKSLKKQYQEYQIIPISKDN
                     FEEYTDIHPVLLKEFKAGKISIQTFSDILRFNLLKNNGGMWVDATIYFTRKVDLFSQL
                     ERQSFATISFSTSKDFLEYKGEFCSWTGYFIASRKNGRFVQMMDMLFREYYLKYRNFQ
                     IYFFIDALFMICKVNKIDSGVLDNPLYIEGNMWTLSNLLKSKYDDQLLTLIKKIPQKL
                     AWFFEPLSDSTDTFYNQLISEKIKQKE"
     misc_feature    11105..11629
                     /gene="wcrV"
                     /locus_tag="SPC17A_0014"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 5.2e-39"
     misc_feature    12140..13009
                     /gene="wcrV"
                     /locus_tag="SPC17A_0014"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis pro, score 7.7e-22"
     gene            13044..14201
                     /gene="wzy"
                     /locus_tag="SPC17A_0015"
     CDS             13044..14201
                     /gene="wzy"
                     /locus_tag="SPC17A_0015"
                     /note="member of homology group 160"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33491.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q4K1D0"
                     /translation="MIKVSKQNAILFLLLLPFFMPTYFEILPFGYLLYRLGMMFSIGY
                     ISLSYLILKKNFSSITWLIVIYEILVVSLTILQKGEIYTAIWNAEKIIGLVLLVDYYQ
                     ENIISFLKVVLVHFEWLIYINFITILLFSERFFSRFTSAYGFTQEWFLGSVNNFIFWF
                     FPALVVAWLYYFLSGKIFRTCSLTVVIALTELIRGSATGRIAVFLFILFVTSSWLRKI
                     ISPKLVFIGVTVLGIFVVFLQNVDFLEPIVVQLLGKKMTFSNRTYIWSNAVTVIQKNF
                     VGLGLQSSDYVIRLLGNINGYLQPTVTHAHNEFLQVAFQTGILGFILYCWIYIKVLIN
                     AVKLSGPIAQTVMLFFAVYNVIAITETLELSQIYMLFPLIYFVMQYTAERK"
     misc_feature    13806..14009
                     /gene="wzy"
                     /locus_tag="SPC17A_0015"
                     /note="HMMPfam hit to PF04932, O-Antigen Polymerase, score
                     6.3e-10"
     gene            14206..15648
                     /gene="wzx"
                     /locus_tag="SPC17A_0016"
     CDS             14206..15648
                     /gene="wzx"
                     /locus_tag="SPC17A_0016"
                     /note="member of homology group 236"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI33492.1"
                     /db_xref="GOA:Q4K1C9"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C9"
                     /translation="MNNEKSLSSKIISGSFWKFGERMSAQAVSFFVSLILTRILSPSD
                     YGIIAIINIFIAIADVLLASGLNTALIQKKNSTRLDYNTIFWCNIILGCVLYLVLFLV
                     APVLADFYNISILTPVIRIFALRLPISSFQSIQNAFVSKHMQFKKFFYATFLGSLVSA
                     VVGITMAYTGFGVWALVAQYLVNTVVGTATLFAIISWRPKFEFSLESAKPLVQYGWKI
                     MFTDLTGTIFNNLGDFIIGAYYNSSSLAFYSKGRQLPYLIRNNIFTSLISVLFPGMSQ
                     VNDDIERIKSFSRKSVSILSFLIFPTMVGLIVTAEPLTILMYTEKWLPIIPFVVIVCS
                     EAILSVIPTVTMQTIKALGRSDLTLKIEFIKKPIYLLTIFVSLNFGIVAIAFTLIINA
                     IIEMIINGLIVQRLIKYSLWEQFNDIFGSLMISIMMGLLSYLVIFLNLNIYLTLLLQV
                     VTGVSSYLILAIVFKNESFIELKNRFLSTE"
     misc_feature    14236..15039
                     /gene="wzx"
                     /locus_tag="SPC17A_0016"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.9e-30"
     gene            15869..17089
                     /gene="ugd"
                     /locus_tag="SPC17A_0017"
     CDS             15869..17089
                     /gene="ugd"
                     /locus_tag="SPC17A_0017"
                     /note="member of homology group 20"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAI33493.1"
                     /db_xref="GOA:Q4K1C8"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C8"
                     /translation="MKLAVVGTGYVGLSISVLLSQHHEVVAVDIIPEKVNLINEGKSP
                     IKDDYIEEYLANKSLNLVATLDASKAYTDADFVIIAAPTNYDSEKNFFDTSAVEKVIE
                     TVLEINPNAVMVIKSTVPVGYTQWVRNKYKTNNILFSPEFLRESKALYDNLYPSRIIV
                     GLDMDDAYLRERAETFAKLLQEGAIKEAIETLYMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDTKAIIEGIGLDPRIGNQYNNPSFGYGGYCLPKDSKQLLANYKDVPQ
                     NMITAIVESNRTRKDFIAEQILKFAEVSSNGDIHTKDVIIGLYRLTMKSNSDNFRQSS
                     IQGVMKRLKAEGVNVIIYEPTLSDNETFWGSKIVNDLEYFKSISNVIVANRYDDLLKD
                     VSDKVYSRDIFKRD"
     misc_feature    15869..16426
                     /gene="ugd"
                     /locus_tag="SPC17A_0017"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 5.2e-50"
     misc_feature    16454..16735
                     /gene="ugd"
                     /locus_tag="SPC17A_0017"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 2.4e-36"
     misc_feature    16817..17068
                     /gene="ugd"
                     /locus_tag="SPC17A_0017"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 5.1e-06"
     gene            17102..18202
                     /gene="glf"
                     /locus_tag="SPC17A_0018"
     CDS             17102..18202
                     /gene="glf"
                     /locus_tag="SPC17A_0018"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI33494.1"
                     /db_xref="GOA:Q4K1C7"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C7"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRNHIGGNIYCED
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPIANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAHMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TDLPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFANRQ
                     ELETSAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     misc_feature    17537..18139
                     /gene="glf"
                     /locus_tag="SPC17A_0018"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 7.4e-136"
     gene            18230..19099
                     /gene="rmlA"
                     /locus_tag="SPC17A_0019"
     CDS             18230..19099
                     /gene="rmlA"
                     /locus_tag="SPC17A_0019"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI33495.1"
                     /db_xref="GOA:Q4K1C6"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C6"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLT
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    18233..18949
                     /gene="rmlA"
                     /locus_tag="SPC17A_0019"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 3.3e-118"
     gene            19100..19696
                     /gene="rmlC"
                     /locus_tag="SPC17A_0020"
     CDS             19100..19696
                     /gene="rmlC"
                     /locus_tag="SPC17A_0020"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI33496.1"
                     /db_xref="GOA:Q4K1C5"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C5"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPASFFTEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     misc_feature    19136..19666
                     /gene="rmlC"
                     /locus_tag="SPC17A_0020"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 1.1e-15"
     gene            19706..20755
                     /gene="rmlB"
                     /locus_tag="SPC17A_0021"
     CDS             19706..20755
                     /gene="rmlB"
                     /locus_tag="SPC17A_0021"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI33497.1"
                     /db_xref="GOA:O54546"
                     /db_xref="HSSP:1KEP"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:O54546"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    19721..20677
                     /gene="rmlB"
                     /locus_tag="SPC17A_0021"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00012"
     misc_feature    19724..20464
                     /gene="rmlB"
                     /locus_tag="SPC17A_0021"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 5.4e-77"
     misc_feature    19727..20539
                     /gene="rmlB"
                     /locus_tag="SPC17A_0021"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/iso, score 1.4e-05"
     gene            20821..21672
                     /gene="rmlD"
                     /locus_tag="SPC17A_0022"
     CDS             20821..21672
                     /gene="rmlD"
                     /locus_tag="SPC17A_0022"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI33498.1"
                     /db_xref="GOA:Q4K1C3"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C3"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELNFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    20821..21669
                     /gene="rmlD"
                     /locus_tag="SPC17A_0022"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 8e-147"
     misc_feature    20824..21453
                     /gene="rmlD"
                     /locus_tag="SPC17A_0022"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 5.2e-19"
     misc_feature    20824..21465
                     /gene="rmlD"
                     /locus_tag="SPC17A_0022"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0001"
     misc_feature    20827..21555
                     /gene="rmlD"
                     /locus_tag="SPC17A_0022"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.4e-08"
     gene            order(21717..21830,21834..22917)
                     /gene="glf"
                     /locus_tag="SPC17A_0023"
                     /pseudo
     CDS             join(21717..21830,21834..22253,22220..22354,22330..22917)
                     /gene="glf"
                     /locus_tag="SPC17A_0023"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
     misc_feature    join(22170..22220,22253..22330,22354..22773)
                     /gene="glf"
                     /locus_tag="SPC17A_0023"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 1.4e-95"
                     /pseudo
     gene            23151..>23198
                     /gene="aliA"
                     /locus_tag="SPC17A_0024"
     CDS             23151..>23198
                     /gene="aliA"
                     /locus_tag="SPC17A_0024"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33500.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C2"
                     /translation="MMKSSKLFALAGVTLL"
BASE COUNT     7612 a   3417 c   4696 g   7473 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attatcgaaa ttcaattaac tttacaaatt cccactattt acttggtggt ttagctctcc
      301 tgttttctct tttagcttta accagccata aatggtatta cgcgagattt ggaaaacgtg
      361 tgatgcttct gttatactac ctgttcgctc acaataagag agaacttttt tacgaaaatc
      421 tattgaatat gccataaaaa gattatacca cattgtgtac tatattatat attatattga
      481 aactagaata gtacacatct gcttctaaaa tattgttaga aaacgatttg actgtcctga
      541 tcaatttgtc atgttcttat ttcattttac tatatttttg gttcgcggga agtctactaa
      601 gatacttaaa gatgcagata gtgaaaataa aggtgtagac attaccgtaa aaaagtgata
      661 taattgtatg atgttcaatg tataggtgtt aatcatgagt agacgtttta aaaaatcaag
      721 ttcacagaaa gtgaagcgaa gtgttaatat agttttgctg actatttatt tattgttagt
      781 ttgtttttta ttattcttaa tctttaagta caatatcctt gcttttagat atcttaatct
      841 agtggtaact gcgttagtcc tactagttgc cttggtaggg ctactcttga ttatctataa
      901 aaaagctgaa aaatttacta tttttctgtt ggtgttctct atccttgtca gctctgtgtc
      961 gctctttgca gtacagcagt ttgttggact gaccaatcgt ttaaatgcga cttctaatta
     1021 ctcagaatat tcaatcagtg tcgctgtttt agcagatagt gagatcgaaa atgttacgca
     1081 actgacgagt gtgacagcac cgactgggac tgataatgaa aatattcaaa aactactagc
     1141 tgatatcaag tcaagtcaga ataccgattt gacgatcgac cagagttcgt cttacttggc
     1201 agcttataag agtttgattg caggggagac taaggccatt gtcttaaata gtgtctttga
     1261 aaatatcatc gagtcagagt atccagacta tgcatcgaag ataaaaaaga tttataccaa
     1321 gggattcact aaaaaagtag aagctcctaa aacgtctaag aatcagtctt tcaatatcta
     1381 tgttagtgga attgacacct atggtcctat tagttcggtg tcgcgatcag atgtcaatat
     1441 cctgatgact gtcaataggg atacgaagag aatccttctt acaacaactc ctcgagattc
     1501 atatgttcct attgctgatg gtggaaataa tcaaaaagat aaattgactc atgcgggcat
     1561 ttatggagtt gattcgtcca ttcacacctt agaaaatctc tatggagtgg atatcaatta
     1621 ctatgtgcga ttgaacttca cttcgttttt gaaattgatt gatttgttgg gtggaattga
     1681 tgtttataat gatcaagaat ttactgccca tacgaatgga aagtattatc ctgcaggcaa
     1741 tgttcatctt gattcagaac aggctatcgg ttttgttcgt gagcgctact ccctagcaga
     1801 tggcgatcgt gaccgtggtc gcaaccaaca aaaggtgatt gtggctatcc ttcaaaaatt
     1861 aacgtcaacc gaagcactga aaaattatag tacgatcatt aatagcttgc aagattctat
     1921 ccaaacaaat atgccacttg agactatgat aaatttggtc aatgctcagt tagaaagtgg
     1981 agggaattat aaagtaaatt ctcaagattt aaaaggtaca ggtcggacgg atcttccttc
     2041 ttatgcaatg ccagacagta acctctatgt gatggaaata gatgatagta gtttagctgt
     2101 agttaaagca gctatacagg atgtgatgga gggtagatga aatgatagac atccattcgc
     2161 acatcgtctt tgatgtagat gatggtccca agtcaaggga ggaaagcaag actctcttgg
     2221 cagaagccta cagacagggg gtgcgaacca ttgtctctac ctctcaccgt cgcaagggca
     2281 tgtttgaaac tccggaagag aagatagcag aaaactttct tcaggttcgg gaaatagcta
     2341 aggaagtggc gagtgacttg gtcattgctt acggggctga aatttactac acaccagatg
     2401 ttctggataa gctggaaaaa aagcggattc cgaccctcaa tgatagtcgt tatgctttga
     2461 ttgagtttag catgcatact tcctatcgtg agattcatag cgccttgagc aagatcttga
     2521 tgttgggaat tactccagtc attgcccaca ttgagcgcta tgatgctctt gaaaataatg
     2581 aaaaacgcgt tcgggaactg atcgatatgg gctgttacac gcaagtaaat agttcacatg
     2641 tcctcaaacc caaacttttt ggcgaacgtt ataaattcat gaaaaaaaga gttcagtatt
     2701 ttttagagca ggatttggtt catgtcattg caagtgatat gcacaatcta gacagtagac
     2761 ctcctcatat ggcagaagca tatgaccttg ttacccaaaa atacggagaa gcgaaggctc
     2821 aggaactttt tatagacaat cctcgaagaa ttgtaatgga tcaactaatt taggagaaat
     2881 gatgaaagaa caaaacacga cagaaatcga tgtatttcaa ttagttaaaa ccttgtggaa
     2941 acgcaagcta atgattttat tagtggcact tgtgacaggt gcgggggctt ttgcatatag
     3001 cacttttatt gttaagccag aatatacgag taccacgcga atttacgtag tgaatcgaaa
     3061 tcaaggagac aagccggggc tgacaaatca ggatttgcag gcaggatctt atctggtaaa
     3121 agactaccgt gagattgtcc tttcgcagga tgtattggaa aaagtagtga caaatttgaa
     3181 gttggatatg ccagcaaaaa cgttagccag caaagttcaa gtgactgtac cagctgacac
     3241 tcgtatcgtc tcaatctctg tcaaggataa acagccagag gaagccagtc gtatcgctaa
     3301 ttttctacga gaagttgctg cagaaaagat cgtcgctgta acgcgagtat ctgatgtaac
     3361 gacacttgaa gaagcgcgac cagctacaac tccctcttct ccaaatgttc gacgcaattc
     3421 cttgtttggt tttcttggag gagcagtcgt aacagtaatt gctgttcttt tgattgagtt
     3481 gctcgacacc cgtgtgaaac gtcctgaaga tgttgaagat gtactgaaaa ttccactttt
     3541 agggctcgtt ccagattttg acaaaataaa ataggaggaa gttatgccaa cattagaaat
     3601 ctcacaggca aaattggatt ctgtaaaaaa ggcagaggaa tattataacg ctttgtgcac
     3661 gaacctacag ttaagtggag atggtttgaa agtattttct atcacttctg tgaaaatagg
     3721 agaaggaaaa tcaacgactt ccgccaatat cgcttgggct tttgcgcgtg caggttacaa
     3781 aacgctgctg attgatggag atattcgcaa ttctgttatg ttaggtgtct ttaaagcaag
     3841 gaataagatt acaggcctga cagaattttt atcaggaact acagacctat cacaagggct
     3901 ttgtgatacc aatatcgaaa atctctttgt aattcaggct ggctctgtgt caccgaatcc
     3961 gacagctctt cttcaaagta agaatttcac tacaatgctt gaaaccttgc gtaaatattt
     4021 tgactacatc attgtagata ctgctcctgt tggtgtcgtg attgatgcgg ctattattac
     4081 gcgaaactgc gatgcttcta ttttagtgac ggaggcaggt gaaataaatc gtcgggatat
     4141 tcaaaaagca aaagaacagt tggaacacac aggaaagccg tttttgggaa ttgtgttgaa
     4201 taaattcgat acttcagtag acaaatacgg ttcttatgga aattatggag attacgggaa
     4261 aaataaaaaa taggtcgggg gatagagatg aatggaaaaa tattaaggtc ttcattggcc
     4321 ataatccaga gttttcttgt tattttattg acttatctac ttagtgctgt gagagaaacg
     4381 gagattgttt caacaacagc tattgcactt tatatcctcc attattttgt cttttatatc
     4441 agtgattatg gacaggattt ctttaaaagg ggatatttga ttgaacttat ccagacattg
     4501 aaatatatcc tattctttgc actagcgatt agtatttcta attttttctt agaggatcaa
     4561 tttagtattt ccagacgagg catgatttac ttcctaacat tacatgctct cttagtctat
     4621 gggctaaacc tatttatcaa gtggtattgg aagcgggctt atcccaactt taaaggaagt
     4681 aagaagattc tcctacttac agcaactttt cgtgtcgaaa aggtactgga tagattaata
     4741 gaatcaaatg aggttgttgg ggagttggta gctgtcagtg tcttagataa accagatttt
     4801 cagcatgatt gtttaaaggt agtagcagag ggggagatag taaactttgt gactaatgag
     4861 gtggtcgatg aagtctttat caatcttcca agtgaaaaat acaatattgg agagcttgtc
     4921 tctcagtttg aaacgatggg aattgatgta acagtcaatc taaatgcttt tgatcgtagt
     4981 ttggcacgta acaagcaaat tcgtgagatg gcaggattaa acgttgtgac tttttctaca
     5041 acattttata agactagtca tgtaatcgct aagcggatta ttgatatcat gggtgcattg
     5101 gtagggctga tactatgtgg tttagtcagt attgtactgg ttcctttgat tcgaaaggat
     5161 gggggctctg ctatttttgc tcagacgcgt ataggaaaaa atggtcgtcg gttcactttt
     5221 tataagtttc gctctatgtg tgtagatgcc gaggcgaaaa aaagagaact catggaacaa
     5281 aataccatgc agggtggaat gtttaaggtg gacgatgatc ctcgtatcac gaaaattggt
     5341 cgttttatac ggaagactag cttggacgag ctaccacagt tttataatgt tctaaaggga
     5401 gatatgagtt tggttggcac acgaccacca acagtggacg agtatgaaca ctatacccca
     5461 gaacaaaaac gtcgtctgag ttttaaacct ggcataacag ggttatggca ggtcagtgga
     5521 cgaagtgaga ttaagaattt tgatgaagtt gtcaaattag atgtagccta tatagacgat
     5581 tggacaattt ggaaagatat tgagatttta ttgaagacag ttaaagttgt attgatgaag
     5641 gatggagcga agtagattga tagatgtaaa aatcattgtg gcaacacata aagaagttaa
     5701 aatgcctcaa gacagtagtc tttaccttcc aatacatgtt gggagagacg gtaaatcaga
     5761 tattggtttt atcggtgata atactggcga taatatatcc tctctaaatc catattattg
     5821 tgagttgacg ggactttatt gggcatggaa aaatcttgat tataattact taggtttagt
     5881 tcattaccgt cgttatttta caaataaatc tcaagggtat aatgaaaata tcaatatgga
     5941 tgacgtcatt ttgtctcgat ctaatgttga aatattatta gagaaatctg acataatagt
     6001 tccaaagaag cgaaagtatt atattgaaac tctttattca cattatgccc atacccttaa
     6061 cggcgaacat ctggatcttg ctaggaaaat tattgagcaa aatagttcag agtatctttc
     6121 atcctttgat aaagtgatga aacaaagaag cggttatatg ttcaatatgt ttatcatgaa
     6181 aaaagaacta ttagatgatt atttaccgtg gcttttttct attctggata ctatgtacga
     6241 acagatggac ttgaccgact atactccatt tgagtcacgt ttgttcgggc gagttagtga
     6301 gttgttgttt aatgtttggt tatgtaaaaa aggaataacg cctaaagagg taccatttat
     6361 gtacatggag agagtggatt tatttgaaaa aggaaaatct tttttaatgg ctaaattttt
     6421 tggaaagaag tatggacaga gtttttgaaa tgttagaaaa agaatctcca ctttttagtg
     6481 ttattgttcc aacctataag atatcagaat ctaatctacg ccaatgtata gactctctgt
     6541 tatatgatag tcaagatgtt gagattattt tggtagatga caataaaaac ttggatatat
     6601 gtggaaaagt gttggacgaa tatgctgaaa aatataataa tatttcagtt attcatcaag
     6661 aaaaccaagg tgtgtcagtc gcaagaaatg ctggtatgtc aattgctgta ggaaagtatc
     6721 ttatttttgt agatcccgat gattgggttg ctgaaaattt ttatagtcaa atgacccttg
     6781 cggttcaaaa aaatccttca agcgatgtga ttatattagc tgctattgta gactacaatg
     6841 gtaaacaatt tacgaatcat ttttggcaca cctctcgttc ttttcaggga acagataaag
     6901 atgatctgga acttcaattg attgctaaag gagcaacgag ttatttccca actgagatag
     6961 gggttggtgt tccctgggca aaaatttatc gtaatgagtt tgtgcgagaa aatggcttag
     7021 attttaatcc ttctcttcgc cgaatgcaag ataatatttt caatatgtat gcatttgaat
     7081 ttgcgaatga aatcgtctac attgatgagc cgatttacta ttatagaaag agtatggata
     7141 gtgtaactaa taagaaaaat gataaagtaa tttattattt cgacttagtt aatgatgagg
     7201 ttgaaaaatt tattcaaaaa tttaataaac ctaaaatatt tgaagatgct ctacatataa
     7261 aaagacttat aggtatcaat tcgtattata agttgtattt taagtttgca tctacttcaa
     7321 gcgagaaaaa gaaaatgcga caagaatttc gtgaactttt agaaagggaa gaatatgtaa
     7381 attcgttaaa aaaagtgaat acagcttatc ttcttccaaa agaaaaaatt tttataagca
     7441 ttttaaagca gaaagactta cggatattct cattgttaca aaaacttgaa aagttgtctg
     7501 tgatgttgaa gagtcgtcag tttagttaga ggggatatga gacagttagc attagaatta
     7561 gtcagtatca tttataaagt aacaaagcga atacctatat cttttatttc taatttaggt
     7621 gagaagattt attcattcaa ggatccctat gtttttaacg tattaagtac attgggagtg
     7681 gataaagaga gcgcctatga tttgatacct ccaaatttat ttttgaataa aatttggatt
     7741 tgctggtttc agggtgagga taaagcacca gatttagtaa aaaagtgtat tgatagtgtt
     7801 cgaaaacatg cctcaggcta cgatgtcatt atcttaacag aaggtaatat agaagaatat
     7861 gttacacttc caaatattgt tttaataaaa tataaaaatg gattatttag ccgaactcat
     7921 ttttcggata tagttcgaat gaatcttctt gcacaacagg gggggctttg gattgatgca
     7981 acgatttttg tgactaggga tttagatttg tctatatttt tcaaaaatga ttttgtaagc
     8041 ttgagaacca caatgaaatc tagtcctctt tttattacgg gatactggac gacatacttt
     8101 gtatatacgc cctctaattt taaattggtt caatatactg ctttattatt aaataaatac
     8161 actgagaaat atgatcgctt tatagattat ttcttacaag attatataat tactaaagca
     8221 attaaagatt tgaattatga atcatacatg gaagaacggc ctgtattggg aaatcaacga
     8281 tggcttttag cagatttggc taataaagtt atgacttcgg atcttcttca acaatttaaa
     8341 caagatacag tgggaattta taaattgaca tataaatcca agtacattag agaaaaaaat
     8401 ggtagggaaa cggtttataa aaaaattgta gaggatggag aatatcttga ataaaaaaat
     8461 aggaattgtt attttaaatt atcttaattg ggaggatact ttagattgca taagtagttt
     8521 gcgattgcaa agtaatcaaa actttgaagc tgtcatagta gaaaatggtt ctcccaatga
     8581 atccgtttct aggattagag attttataaa aaatgacaag aatattcatc tttatgtagt
     8641 agagaataac ttaggttatg caaatggaaa taatatgggc atcctctact taaaaaataa
     8701 atactctata aatagaatta tattaactaa taatgatgtt atatttgatg ataaaaatta
     8761 tataagtaaa ttaatagaca ttgaatatga tgggaatatt ggagctattg gaacaaaaat
     8821 tattggttct gatggtttaa accaaaatcc agcttatttt ccaatttctt ttagttctag
     8881 tataaaatca cttattatta atttattggc attttctaaa gttattgctt ctatcaaaaa
     8941 gcgttttcta tcttcatggg cgaaaaaagc taatgatttt tcaagtccaa agactagtaa
     9001 acaaaaatac tttctacatg gatcggttat ttttcttacg gaaaattatt tagataagtt
     9061 tatggggttg tatggtggga cttttcttta ctatgaagaa gtaatcctag gtattatatt
     9121 tgaaaaggca ggtcttgata tgctgtatat acctgagttt tcaatttacc ataaagagga
     9181 ccaatcttca attcgaagct ttaataatga tgacttagta cgacgtcgtt atttgttgaa
     9241 tagcatttgg tctagtttta aagtttatct tgctaaccag gaagaactcc cgaatattgt
     9301 tagtgactct atatataaac atattaagga ataggaatta ttatggtcaa aaaaattgct
     9361 ttctatcttc ctcagtttca taccattcca gaaaacgata agtggtgggg aaaagatttt
     9421 actgaatgga ctaatgtgaa gaaatctcag ccccaataca gaggacatat tcagcctgaa
     9481 gttccattaa atgaagaata ctataacctc ttagatacag aagttcaaga aaaacaagca
     9541 aaattagctt tagagtacgg tattgatggt ttttgctatt atcattattg gtttgatgga
     9601 aagctccttc tggagaaacc tatggagaat atgctgcaaa atgagaatat aactttaccc
     9661 ttttgtattt gttgggctaa tgagagctgg tcgagaactt gggatggtgc tgaaagtaag
     9721 gtcttaatta tgcaaaatta ctcagatact ttggatggat ggaagaggca ttttgattat
     9781 cttttaccct tttttaaaga tgaacgttat atcaaggttg atgaaaaacc aatgatgatt
     9841 atttacaagc ctcaactaat tgagaactta gaagagatga ctgtttattg gaaccaattg
     9901 gctaaacaaa atggttttaa gggtattcat tttggacatc agcatgtttc atcttttgaa
     9961 gattcaaaag taatagaaaa ctttgatttt ggtattgaat ttgaaccaat ctatacggta
    10021 tctgagatgc ataaaagtac aagaagtaag tcagaaaaat taaagcgggc aataaaaaat
    10081 cctaaatggt tttcaagaaa tatcagccat aaatattttg gccgttcgct cttatttgac
    10141 tatgatgaag tatggtcagc tattttacgg cgtgaaggaa gaaaaaatat ttcaccaggt
    10201 gcctttgtgt catgggataa tactccgaga cgcgggaacc gctctctagt atttgatggt
    10261 gcaaatccta aaaagtttga gaaatatttt gctaagcaag tacaacgtgc gaaagaagaa
    10321 tatcattctg atttcatatt tattaacgct tggaatgaat gggcagaagg ggctcattta
    10381 gagcctgatg agcagtatgg ttacggttat ttagaagcgg tgagagctgt aaaggaggaa
    10441 tagtgtgtta attggtcgtc tgaaacaaag gctgaagatt gaaaaattta ggagatcatg
    10501 gcgagaaaaa aatacgcata atactacaat ggcgagtagt atttttgata tagataaagt
    10561 ttcagtggga aattacactt atggaaatat cgatatccta gattttggaa ctaatgaaaa
    10621 acttagtata ggaagttttt gttcaatagc gccgaatgtt aaatttattc tgaatgctga
    10681 ccactgcacc aattacttca ctacctttcc attaaaggta aaagttctac aaaatcaaga
    10741 taaagaagga atttcaaagg gtgatattat cgtgggtgat gatgtatggt tggggcttaa
    10801 tgcagtcatt ctttcaggtg taacgattgg acaaggagct ataattgcgg caggagcagt
    10861 ggtaaccaaa aatgttccac cttatgctat cgtcggtggc aatccagcac gaataataaa
    10921 gtatagattt gaagctgaaa taattgataa actgttaaaa gttaattttt caaaattatc
    10981 taagtatgat atagaaaaac atataaaaca aatgtatata ccattagttg aggtaaaaca
    11041 actagattgg atagacgact tattacatta agaggtagaa taagtgaaat ctgaaattaa
    11101 agtttctgta gtaattccaa tatataatca agagatttac ttaaggaagt caatacattc
    11161 agtactgact cagagttatc aaaatttgga aattatagcc gttaatgacg gttcaattga
    11221 ttcaagtcaa caaattatgg aagaatttgc aaatcaggat agcaggattt ttctttatga
    11281 aaaatcaaat ggtggattag ttgatgcaac aatatatggt gtagaaaagg ctacggggga
    11341 ttatatagtc tttcttgatc cagatgatta cattggggaa aattatattc aaaagtttgt
    11401 atcttacctc gaccatgact atgattttgt agctatggga ttttattatg atgataacga
    11461 taaggttact ccatacagat taaaagagaa tctaattcta aataagactc atatagaagt
    11521 attaaaatca accttcttaa ctaattttga tttagggact atttcgaatc agatatttat
    11581 ttcaagatgg aataaacttt accgctgtga tattgtcaaa agtgttattt cggagtttaa
    11641 gtcatataag aatgtaactc tcggagaaga tacaattttt gctgctctgt tacttaaata
    11701 ttctcagtca gctaaaattt tgcaacaagc taatacttat ttctataata ttgcaaatca
    11761 gaattctatg atgaaaagta gcgatttaga taagtatttg aacaaatgtt atcaagtatt
    11821 tatgagtttt agtaaattac ttgaagagca agaattagat aaaactcaag cttactatct
    11881 gtattttttc ttaactaata ctctttttaa cagattaagg actaatgatc caaaacagtt
    11941 ttatggttta tttgataaac ttaagagaga accagtatat ataaaaacat taaatatggt
    12001 tcgaaaaaat acgaaaagta agtttataag tttcgatctg tttttaagac tctatacgac
    12061 ttgttcacaa tatatatata taaaggatag tattgaacgt actaagacct ttgtacggaa
    12121 ttttaaatat tttagtcggc aagtcagaaa aaataatatt attaaggcct atcagctatt
    12181 gaattttttt aggagtcgtc aaaatgcttt ttatgagtta aaaaatcaac ttcctaagat
    12241 tgagggagaa ataaataaca ttttacttca acatgatagt aatgaattta atgaagaaga
    12301 aggcatagaa gaaaagattt ttgttttttg gtgggatgga tttaatgatt taccagaaat
    12361 tgttgcagaa tgttttaagt ctttgaagaa gcagtatcag gaatatcaga ttattcctat
    12421 ttctaaagac aattttgaag agtatacgga tattcatcct gtgttgttaa aagagtttaa
    12481 agctggtaaa atttctatac agactttttc tgatattttg aggtttaatt tattgaaaaa
    12541 taatggtggt atgtgggtag atgcaacaat ctactttacg aggaaagttg atttgttttc
    12601 acagttagaa agacaatcat ttgctacaat aagtttttcc acaagcaaag attttttgga
    12661 gtataaagga gagttttgca gttggacagg ctattttatt gcttcacgga aaaatggccg
    12721 ctttgttcaa atgatggata tgttatttag agagtattat ctcaaataca gaaattttca
    12781 aatttatttt tttattgatg cattgtttat gatttgtaaa gttaataaaa ttgatagtgg
    12841 tgttttggat aatccattat atattgaagg gaatatgtgg acgctgtcaa acttactaaa
    12901 atcaaaatat gatgatcaat tattaacttt gattaaaaaa attccccaaa agttagcttg
    12961 gttttttgaa ccacttagcg atagcacgga tactttctat aatcaattaa tttcagaaaa
    13021 aatcaagcaa aaggagtaga actatgatta aagtgtctaa acagaatgct atattattct
    13081 tattactgct cccgtttttt atgccaactt attttgaaat tttaccattt ggatacttgt
    13141 tgtatagatt aggcatgatg tttagcatag gatatatttc tttatcttac ctaatattaa
    13201 agaaaaattt ttcttccatc acctggttga ttgttatcta tgagatatta gtagtttctt
    13261 taacaatttt acaaaaaggt gaaatctata ctgcaatatg gaatgcagaa aaaattattg
    13321 gactggtttt attagtagat tactaccaag aaaatattat tagcttctta aaagttgtac
    13381 tggtacattt tgagtggttg atttatatca attttattac aattttatta ttttcagagc
    13441 gctttttttc tagattcact tctgcttatg gttttaccca agaatggttt ctaggttccg
    13501 tcaataactt tattttctgg ttttttccag ctcttgtagt agcgtggttg tattattttt
    13561 tgtcaggtaa aatttttaga acgtgtagtt taacagttgt tattgcttta acagaattaa
    13621 ttagaggctc agcaacgggg aggattgcag tatttctatt tatcttattt gttacctcgt
    13681 cttggttacg taagattatt tcgccaaagt tagtatttat aggtgttact gtcctaggaa
    13741 tttttgttgt atttctccaa aatgtagact tcttagagcc tattgtggta cagttacttg
    13801 gtaaaaaaat gacatttagc aatcgtacct atatctggtc gaatgctgtg acagtaattc
    13861 aaaagaattt cgttggtcta ggtttacaat catctgatta tgtcattcga ttgcttggaa
    13921 atattaatgg ttatttacaa cctacggtaa cccacgccca taatgagttt ttacaagttg
    13981 cttttcaaac aggaatttta ggatttattc tttattgttg gatatatatt aaagtcttga
    14041 tcaatgcagt aaagttgagt ggaccaatag cgcaaactgt tatgctgttt tttgctgttt
    14101 ataatgttat tgctataaca gaaacgttag aactgagtca aatatatatg ttatttcctt
    14161 tgatttattt tgtaatgcaa tatactgcag aaagaaagta aggtaatgaa taacgaaaaa
    14221 agtttaagct ccaagataat atcaggaagt ttttggaaat tcggagaaag aatgagtgca
    14281 caggcggttt ctttttttgt ttctctgatt ttaacacgaa tcttatcccc aagtgattac
    14341 gggattattg cgattattaa tatttttata gctattgctg atgtactttt agctagtggt
    14401 ttaaatactg ctttgataca gaaaaaaaat tcaacgagac tagattataa tacgattttt
    14461 tggtgtaata ttatactggg ttgtgttctg tatctagtat tatttttagt agcaccagtc
    14521 cttgcagatt tttataatat ttctatactt acaccagtca ttcgaatttt tgcactgcgg
    14581 ttacccattt cttcttttca atcaattcaa aacgcatttg tttctaagca tatgcagttt
    14641 aagaagtttt tttacgccac ctttttgggt tcgctagtat ctgctgttgt tggaattaca
    14701 atggcttata caggttttgg tgtatgggca cttgtagcac aatatttagt aaatacggtt
    14761 gttggaacag ctacactatt tgctatcatt agttggcgtc caaaatttga attttctttg
    14821 gaaagtgcca aacccttagt ccaatatggc tggaagataa tgtttacaga ccttacaggt
    14881 acgattttca acaatttagg agactttatc attggcgcat actataattc atcttcactt
    14941 gctttttatt ctaaagggcg ccaattaccc tatctaatta gaaataatat ttttacttct
    15001 ttgataagtg tactcttccc aggaatgtct caggttaatg atgatattga acgtattaaa
    15061 tctttttcac gtaagagtgt ctcaatctta tcttttttaa tttttccaac aatggttggt
    15121 ttaattgtga ctgctgaacc actaactatc ttaatgtata ctgaaaaatg gctacctatt
    15181 attcccttcg ttgtgattgt atgttcggaa gcaattttat cagttatacc aacggtaaca
    15241 atgcagacaa ttaaagcatt aggacgtagt gatttaacac taaaaataga atttataaaa
    15301 aagcccattt atctattaac gatttttgta tctttaaact ttggaatagt ggctattgcc
    15361 tttacattaa ttattaatgc gattattgaa atgattatta atggtttaat tgtacaaaga
    15421 ctaatcaagt actctttgtg ggaacaattt aatgatatat ttggttcatt aatgatttca
    15481 attatgatgg gcttattatc atatttagtg atttttttaa atttaaacat ttatctcaca
    15541 ttattgttac aagttgttac tggtgtctct agttatctca ttttagctat tgtatttaaa
    15601 aacgaatcat tcattgagtt gaaaaataga tttttgagca ctgagtagta ttaagtctaa
    15661 gaattatcct gcgggaatag ctggtgaatt tttgggggtg aaaaggactt gggtaagata
    15721 ttttataatg aagccctagc aataatgtgt ttatttcatg cccccatttg ttctggaaaa
    15781 acttgtaata gttaagtgat aactaatagc caatgaaact tgggattgaa attattccca
    15841 tgaatatgta taatgaggag gagttaaggt gaaacttgca gttgttggaa ccggatacgt
    15901 tggattgtct atctcagttc tattatctca gcatcatgag gtggtggctg tcgatattat
    15961 tccagaaaaa gttaatctaa ttaatgaagg gaagtcccct attaaagatg attatattga
    16021 agaatattta gcaaataagt ctcttaattt ggtagcgacg ttagatgcat ctaaggcata
    16081 tactgatgct gattttgtaa ttattgcagc gccaacaaat tatgattcgg aaaagaactt
    16141 ttttgataca tctgctgtag agaaagttat tgaaacagtg ttagagataa atcctaacgc
    16201 tgttatggtt attaaaagta cagttcctgt aggatatact caatgggttc gtaataaata
    16261 taaaacaaat aatattttat ttagtccaga atttctgcgt gaatcaaagg ctttatatga
    16321 caatttatat cctagccgta taattgttgg acttgatatg gacgatgcat atttgaggga
    16381 gagggccgaa acttttgcaa aactgcttca agaaggagct attaaagagg ctatagaaac
    16441 tctttatatg ggatttacag aagctgaagc agttaaactc tttgcaaata catacttggc
    16501 cttacgagtt tcgtatttca atgagttgga tacttatgca gaagttaaag ggttagatac
    16561 caaagctatt attgagggta ttggcttaga tccacgtatc ggaaaccaat ataataatcc
    16621 ttcttttgga tatgggggat attgccttcc aaaagatagc aaacaattac tggcaaacta
    16681 taaagatgtt ccacagaata tgataacagc tattgttgag agtaatcgta ctagaaaaga
    16741 ttttattgca gagcagattt tgaaatttgc agaagtgtca agtaatgggg acattcatac
    16801 aaaagatgta ataataggtc tttatcggtt aactatgaag agtaattccg ataattttcg
    16861 tcaatcttct attcaaggtg ttatgaaacg attaaaggca gaaggtgtaa atgtcataat
    16921 ttatgaacca accctcagtg acaatgagac attttggggt agtaagattg taaacgattt
    16981 ggagtatttt aaatcaatta gtaatgttat cgtggcaaat cgttatgatg atttgcttaa
    17041 agatgtgagt gacaaggttt atagtcgtga tatttttaag agagattagg tagaagttac
    17101 aatgtatgat tatttaatcg ttggtgctgg tttgtcggga gcaatttttg cttatgaagc
    17161 aaccaagcgt gggaaaaaag taaaagtgat tgataagcgt aatcatattg gtggtaatat
    17221 ctactgtgag gacgttgaag gtatcaacgt tcacaagtac ggtgcccaca ttttccatac
    17281 ttcaaacaaa aaagtctggg attatgtaaa tcaatttgct gaatttaaca actatatcaa
    17341 ctcgcctata gccaattaca agggcagtct ttacaatctt ccttttaaca tgaatacttt
    17401 ctatgctatg tggggaacca agactcctca agaagtgaaa gataagatag ctgaacaaac
    17461 ggctcatatg aaagatgttg agcctaaaaa cttggaagaa caagctatta agttgattgg
    17521 tccggatatc tatgaaaagt tgattaaggg atatactgaa aaacaatggg gacgttctgc
    17581 gacagacctc ccaccattta tcattaaacg tctaccagtt cgtttaacct ttgataataa
    17641 ttattttaat gaccgttatc aagggattcc aattgggggt tacaacgtta tcatcgaaaa
    17701 tatgctgaag gatgtagaag tagaacttgg cgttgacttt tttgccaatc gtcaagaatt
    17761 agagacttct gctgaaaaag ttgtcttcac agggatgatt gaccaatact ttgattataa
    17821 gcatggtgag ttagaatacc gtagtcttcg ttttgagcat gagattttag acgaggaaaa
    17881 ttatcaaggg aatgctgtag tgaactatac agagcgtgag atcccttata ctcgtatcat
    17941 cgaacacaaa cattttgaat atggaatgca gccaaagaca gttatcacgc atgaatatcc
    18001 agctgactgg aagcgtgggg acgagcccta ctatcctatt aacgatgaga aaaataatgc
    18061 tatgtttgct aaataccaag aagaagcagc gcagaatgat aaagttatct tttgtgggcg
    18121 tttagcagac tataaatatt acgatatgca tgtggtgatt gaacgggcgc ttgaggttgt
    18181 ggagaaagaa tttagtaatt gaaaaacaac gaagaaaggt tgcttatata tgaaaggtat
    18241 tattcttgca ggtggttcgg ggacacgatt atatcctttg actcgggctg catcaaaaca
    18301 acttatgccg gtttatgata aacccatgat ttactatcct ttgtcaaccc tgatgttgac
    18361 tggaataaag gacattttga ttatctcaac accacaggat ttgccccgtt ttaaggactt
    18421 gctcttggat ggttccgaat ttgggatcaa gctttcctat gcggaacaac ctagtcccga
    18481 tggacttgct caggctttta ttatcggtga agagtttatc ggtgacgata gcgttgcctt
    18541 gattttaggt gacaatatct accatggtcc tggtctgagc acaatgctac aaaaggcagc
    18601 gagtaaggag tcgggagcaa ctgtttttgg ctaccatgtc aaggatccag agcgctttgg
    18661 tgtggttgag tttgatcagg atatgaaggc tatttctatt gaagaaaagc cagagcaacc
    18721 tcgttcaaac tatgcagtta caggtctcta tttctatgat aatgatgtag tagagattgc
    18781 caagagtatt aaaccaagtc ctcgtggtga actggaaatt acagatgtaa acaaggctta
    18841 cctagatcgt ggtgatttgt ctgttgagct tatgggacgt ggctttgctt ggttggatac
    18901 tggcactcat gaaagtttac tagaggcttc gcagtacatc gaaacagtcc aacggatgca
    18961 aaatgttcag gtagcaaact tagaagaaat tgcttaccgt atgggctata tcagtcgaga
    19021 agatgtattg gccttagccc aaccacttaa gaaaaatgaa tacggacagt atctgctccg
    19081 tttgattgga gaagcataga tgacagataa ttttttcggt aagacgcttg cggcacgcaa
    19141 ggttgaagct attccaggca tgttggagtt tgatatcccc gttcatggag ataatcgtgg
    19201 ctggtttaaa gaaaatttcc aaaaggaaaa aatgcttcca cttggatttc cagcgtcttt
    19261 ctttacagaa ggaaaattgc aaaacaatgt atccttctca cgtaaaaatg tccttcgagg
    19321 cctccacgca gagccttggg ataagtacat ctctgtagca gatggaggga aagttctggg
    19381 ttcttgggtt gatctacgcg agggtgaaac ctttgggaat acctatcaga cagtaattga
    19441 tgcaagcaag ggaatctttg ttcctcgagg cgtagctaat ggcttccaag ttttatcaga
    19501 tacagtgtca tatagctatc tggtcaatga ttactgggcg cttgaactca aacccaagta
    19561 tgcctttgtg aactacgctg atccaagcct tggtattgaa tgggaaaata ttgcagaagc
    19621 agaggtttca gaagcagata aacatcatcc cctacttaag gacgtgaagc ctttgaaaaa
    19681 agaagatttg gaataaggaa agaatatgac tgaatacaaa aatattatcg tgacaggtgg
    19741 agctggcttt atcggttcta actttgtcca ttatgtttac gagaactttc cagatgttca
    19801 cgtgacagtc ctagataagt tgacttatgc tggaaaccgc gcgaatattg aggaaatttt
    19861 aggtaatcgt gttgagttag ttgttggtga cattgctgat gcggagttgg tagacaagtt
    19921 ggctgctcaa gcagatgcta tcgttcatta tgcagcggaa agccacaatg ataattcgct
    19981 caatgatcca tcgccattta ttcatactaa cttcatcgga acctatactc ttttagaagc
    20041 tgctcgtaag tatgatattc gcttccacca tgtatcgaca gatgaagttt atggggatct
    20101 ccctttacgc gaagatttgc caggtcatgg tgaaggacca ggtgagaaat ttactgctga
    20161 aacaaaatac aacccaagct ctccgtactc atcaaccaag gcagcctcag atttgattgt
    20221 caaagcctgg gtgcgttctt ttggagtcaa agcaacgatt tccaactgtt caaataacta
    20281 cggtccttat caacatatcg aaaaattcat cccacgtcag attactaaca tcctaagtgg
    20341 tatcaagcca aaactttacg gtgaaggtaa gaacgttcgt gattggattc ataccaatga
    20401 ccattcttca ggagtttgga caatcttgac aaaagggcaa atcggtgaaa cctacttgat
    20461 tggggctgat ggtgagaaga acaataagga agttttggaa cttatcctta aggaaatggg
    20521 acaagctgcg gatgcctatg atcatgtgac tgaccgtgca ggacatgacc ttcgctatgc
    20581 gattgatgct agcaagctcc gtgatgagtt ggggtggaaa cctgaattta ccaactttga
    20641 agctgggctc aaggcaacaa tcaagtggta tacagataac caagaatggt ggaaagcaga
    20701 gaaagaagct gttgaagcca attatgctaa gactcaggag attattacag tataaaaagc
    20761 aggaaatagc tgctttttat tgctatattg ggaagagtta catattagaa aggtctagag
    20821 atgattttaa ttacaggggc aaatggccaa ttaggaacgg aacttcgcta tttattggat
    20881 gaacgtaatg aagaatacgt ggcagtagat gtggctgaga tggacattac cgatgcagaa
    20941 atggttgaga aagtttttga agaggtgaaa ccgactttag tctaccactg tgcagcctac
    21001 accgctgttg atgcagcaga ggatgaagga aaagagttga acttcgccat caatgtgacg
    21061 gggacaaaaa atgtcgcaaa agcatctgaa aagcatggtg caactctagt ttatatttct
    21121 acggactatg tctttgacgg taagaaacca gttggacaag agtgggaagt tgatgaccga
    21181 ccagatccac agacagaata tgggcgtact aagcgtatgg gggaagagtt agttgagaag
    21241 catgtgtcta atttctatat tatccgtact gcctgggtat ttggaaatta tggcaaaaac
    21301 ttcgttttta ccatgcaaaa tcttgcgaaa actcataaga ctttaacagt tgtaaatgac
    21361 cagtacggtc gtccgacttg gactcgtacc ttggctgagt tcatgaccta cctagctgaa
    21421 aatcgtaagg aatttggtta ttatcatttg tcaaatgatg cgacagaaga cacaacatgg
    21481 tatgattttg cagttgaaat tttgaaagat acagatgtcg aagtcaagcc agtagattcc
    21541 agtcaatttc cagccaaagc taaacgtccg ctaaactcaa cgatgagcct ggccaaagcc
    21601 aaagctactg gatttgttat tccaacttgg caagatgcat tgcaagaatt ttacaaacaa
    21661 gaagtgagat aagtagtaga atgattttct agtctaataa aagaggcaga taatgaactc
    21721 caaaggagct taagatatac aattatcttg ttgttggtgc tggtctcttt ggtgcagtct
    21781 ttgcccatga agcggcctta aaaggaaaaa aagtaaaagt tattgaaaaa tgaaatcata
    21841 tcgcgggtaa tatctatact cgtgaagagg aaggaattca agtttatcaa tatggtgctc
    21901 atatcttcca tacttctgat aaggagatct gggattatgt aaatcagttt gcagagttta
    21961 accgttacat aaattctcct gttgcaaact ataagggtga gatttataac cttcctttta
    22021 atatgaatac tttcaataaa ctctggggag ttgtaacgcc agcagaagca caagctaaga
    22081 ttgatgaaca acgtgctatt ttaaatggta aaactcctga aaatttggaa gaacaggcga
    22141 tttctcttgt agctacagac atctacgaaa aattaatcaa agactataca gagaaacagt
    22201 ggggcaaacc aactactgaa cttccatcct ttattattgt ttgccagtac gcctgaccta
    22261 tgataacaac tattttaacg atacctatca agggattcca attggtgaat acactcaaat
    22321 agttgaaaaa tgttggatca tgaaaatatt gatgtagaaa caaacgttga tttctttgtg
    22381 aataaagagc aatatctgaa agattttcct aagattgtct ttactggtat gattgatgaa
    22441 ttctttgact ataagttggg cgaactagag taccgtagtc ttcgttttga aaatgagacc
    22501 ttggatatgg aaaattacca aggaaatgca gttgtgaact atacggatgc agaaacccca
    22561 tatactcgca ttattgaaca caaacatttt gagtttggga gtcaagcaaa gactatcatt
    22621 actaaagaac attctaaaac atgggaaaaa ggtgatgagc cttattatcc agttaataat
    22681 gatcgtaata atcatttgta taaatcatat aaaaaacttg ctgatgagca agggaatgtt
    22741 atctttggtg gccgcttagg acactatcgt tattacgata tgcaccaagt aattggagca
    22801 gctttgcagt gcgtgagaaa tgagttagat tcatactcaa tgaaaatcaa agagcaaact
    22861 aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgcagatgg aagctgacgc
    22921 ggtttgaaga gattttcgaa gagtataaac aagtaaaact gactaccagt tattatttag
    22981 aaatagtatt aaaaattcct tgactatgtg atatagttga gggattttta aatgatattc
    23041 atattttttg caaagatgtt gtttgaaaaa taattttcaa aaattctgaa aattctgttg
    23101 acaactttct gaaaagagtc tataatggag agaaagtttt aaaggagaaa atgatgaaaa
    23161 gttcaaaact atttgccctt gcgggcgtga cattattg
//
