LOCUS       CR931674               22849 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain Gethens (serotype 18f).
ACCESSION   CR931674
VERSION     CR931674.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22849)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22849)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Gethens"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC18F_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC18F_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI33596.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..461
                     /gene="aliB"
                     /locus_tag="SPC18F_0002"
                     /pseudo
     CDS             293..461
                     /gene="aliB"
                     /locus_tag="SPC18F_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(459..1325)
                     /gene="tnp"
                     /locus_tag="SPC18F_0003"
                     /pseudo
     CDS             complement(459..1325)
                     /gene="tnp"
                     /locus_tag="SPC18F_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(930..1307)
                     /gene="tnp"
                     /locus_tag="SPC18F_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 9.3e-21"
                     /pseudo
     gene            1560..3005
                     /gene="wzg"
                     /locus_tag="SPC18F_0004"
     CDS             1560..3005
                     /gene="wzg"
                     /locus_tag="SPC18F_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33599.1"
                     /db_xref="GOA:Q4K240"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K240"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGIDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEINDSSLASVKTAIQDVLEGR"
     misc_feature    1560..1676
                     /gene="wzg"
                     /locus_tag="SPC18F_0004"
                     /note="Signal peptide predicted for SPC0938 by SignalP 2.0
                     HMM (Signal peptide probability 0.993) with cleavage site
                     probability 0.538 between residues 39 and 40"
     misc_feature    1764..2111
                     /gene="wzg"
                     /locus_tag="SPC18F_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 2.3e-64"
     misc_feature    2289..2732
                     /gene="wzg"
                     /locus_tag="SPC18F_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 1.1e-69"
     gene            3007..3738
                     /gene="wzh"
                     /locus_tag="SPC18F_0005"
     CDS             3007..3738
                     /gene="wzh"
                     /locus_tag="SPC18F_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33600.1"
                     /db_xref="GOA:Q4K239"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K239"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLERDLVHVIASDMHNVDSRPPHMAEAYDLVS
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    3010..3618
                     /gene="wzh"
                     /locus_tag="SPC18F_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 6.8e-38"
     gene            3747..4439
                     /gene="wzd"
                     /locus_tag="SPC18F_0006"
     CDS             3747..4439
                     /gene="wzd"
                     /locus_tag="SPC18F_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33601.1"
                     /db_xref="GOA:Q4K238"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K238"
                     /translation="MKEQNTIEIDVFQSLKTLWKYKLIILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDVLEKVATNLKLD
                     IPAKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGGAAVTVITVLLIELLDTRVKRPEDVEDVLQMP
                     LLGVVPDFDKMK"
     misc_feature    3765..4181
                     /gene="wzd"
                     /locus_tag="SPC18F_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 4.7e-51"
     misc_feature    4287..4364
                     /gene="wzd"
                     /locus_tag="SPC18F_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4449..5132
                     /gene="wze"
                     /locus_tag="SPC18F_0007"
     CDS             4449..5132
                     /gene="wze"
                     /locus_tag="SPC18F_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33602.1"
                     /db_xref="GOA:Q4K135"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K135"
                     /translation="MPTLEISQVKLELAKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLGTLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGAY
                     GSYGNYGKK"
     gene            5148..6515
                     /gene="wchA"
                     /locus_tag="SPC18F_0008"
     CDS             5148..6515
                     /gene="wchA"
                     /locus_tag="SPC18F_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33603.1"
                     /db_xref="GOA:Q4K134"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K134"
                     /translation="MDEKGLKIFLAVLQSIIVILLIYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKDFGRNKQIHEMVGLDVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAESIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     misc_feature    5931..6512
                     /gene="wchA"
                     /locus_tag="SPC18F_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 4.1e-146"
     gene            6546..7718
                     /gene="wchF"
                     /locus_tag="SPC18F_0009"
     CDS             6546..7718
                     /gene="wchF"
                     /locus_tag="SPC18F_0009"
                     /note="member of homology group 15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33604.1"
                     /db_xref="GOA:Q4K133"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q4K133"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKAIQYYVACMR
                     ENSAKSGTTEDVFEHNGAICYNVDVPNIGPARAIVYDIAAINRAIKIAKENKDEDPIF
                     YILACRIGPFIHGIKKKIQEIGGTLLVNPDGHEWLRAKWSAPVRRYWKISEGLMVKHA
                     DLLVCDSKNIEKYIQEDYKQYQPKTTYIAYGTDTTRSILKSSDEKVRSWFKKKNVSEN
                     EYYLVVGRFVPENNYEAMIRGFLASNSKKDFVLITNVEQNKFYNQLLASTGFDKDPRV
                     KFVGTVYDQELLKYIRENTFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     QSAIYWKKDELSQVIEKVEQFDAKMIDELDRQSNQRIVDFFTWEKIVTDYEKLFKK"
     gene            7715..8986
                     /gene="wciU"
                     /locus_tag="SPC18F_0010"
     CDS             7715..8986
                     /gene="wciU"
                     /locus_tag="SPC18F_0010"
                     /note="member of homology group 59"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33605.1"
                     /db_xref="GOA:Q4K132"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K132"
                     /translation="MKILHYTLGFQPQRTGGLVKYAEDLMLEQIAQGYQVAALYPGRI
                     KFFSKKIEIIKATSRQFECYELLNSLPMALFGGISDPTAFLTPCDKNVYRTFLEKVQP
                     DIIHIHSFMGLHKEFLEIAKNLNIRVVFTSHDYYGLAPVPHFYFNGVDYSDKSTNLTW
                     NIMSSNALSVKKLRLFQVSFYPTIRKLLKLLGKNPKSKKNLVIRDVIEEQDYSELRYY
                     YNEMFHLIDGYLFNSRLAKKVYEINEIKSANSIVLSITNSSINHHQRLTTTNNKIRVA
                     YIGPDEEYKGYFDFVDFVETLDRESYEVATYGHLPNEECPSFIEQKGYFTKEMIDSVY
                     ENIDILIVPSKWKETFGLITVEALSYGVNVFVSENVGSKDLLPESHVFKNQNDLVVKF
                     LKNDIENTKLKTLDEHSIEVIQYYERVINDS"
     misc_feature    8489..8950
                     /gene="wciU"
                     /locus_tag="SPC18F_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 0.0015"
     gene            8976..9662
                     /gene="wcxM"
                     /locus_tag="SPC18F_0011"
     CDS             8976..9662
                     /gene="wcxM"
                     /locus_tag="SPC18F_0011"
                     /note="member of homology group 105"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33606.1"
                     /db_xref="GOA:Q4K131"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="UniProtKB/TrEMBL:Q4K131"
                     /translation="MIVKSFIKKITGKTVDIHPDVPLSYILQRGINYGFGLFRGVVRG
                     IGFGQNDKRLFIGQGVSILAKRKLFVGKNVRIGKKVSIDALSKEGIHFADNVKIGDYS
                     QIIGTGSIKNMGIGLKIGKNSSFSEYSLFGSAGGITIGDNVIAGQNVRFHAENHNYSD
                     LDKLIVEQGVSRKGISVGDNCWIGAGSVFLDGSSIGSGCVVGANAVVTKQFPDNVIIG
                     GVPARILAYR"
     misc_feature    9174..9227
                     /gene="wcxM"
                     /locus_tag="SPC18F_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 16"
     misc_feature    9240..9293
                     /gene="wcxM"
                     /locus_tag="SPC18F_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 13"
     misc_feature    9381..9434
                     /gene="wcxM"
                     /locus_tag="SPC18F_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 10"
     misc_feature    9495..9548
                     /gene="wcxM"
                     /locus_tag="SPC18F_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 11"
     misc_feature    9549..9602
                     /gene="wcxM"
                     /locus_tag="SPC18F_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 0.77"
     gene            9694..10740
                     /gene="wciV"
                     /locus_tag="SPC18F_0012"
     CDS             9694..10740
                     /gene="wciV"
                     /locus_tag="SPC18F_0012"
                     /note="member of homology group 91"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33607.1"
                     /db_xref="GOA:Q4K130"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K130"
                     /translation="MPTFSVVVPVYNVENYLSQCLNALVNQSFKDFELILVNDGSTDT
                     SGSLCEEWGKKDHRIKVIHKTNEGLGFARNTGIENCTGDYIVFVDSDDYVSYEMLEIY
                     DTYLQRFNADVIYSENFYRVDNKGNIIEPLDQSLDSIFYKNDSIFTELLPDVISSPPE
                     FIGDGKIGVSVWKGVYKRSLFKDKGLLFHSEREFISEDAIFQIDCLKLAISALVIPDI
                     LYYYRENFGSLSMKYKEDRFELNKILYNEQLKRVEGLPNQEILEERIERILIANIRLC
                     IFQESLYKNSRIHKRLQRIRQICKDPISKSVLRHYPIRRLPFSKRLICVLAKYNMPLM
                     LLVLTLLKYRNRSV"
     misc_feature    9706..10248
                     /gene="wciV"
                     /locus_tag="SPC18F_0012"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 2.7e-41"
     gene            10746..11657
                     /gene="wciW"
                     /locus_tag="SPC18F_0013"
     CDS             10746..11657
                     /gene="wciW"
                     /locus_tag="SPC18F_0013"
                     /note="member of homology group 92"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33608.1"
                     /db_xref="GOA:Q4K129"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4K129"
                     /translation="MGMNIEKLKLSLKNGTFFSVVIHALRNRWPLWWIGNKAIREVQL
                     EDRAYRILKKKYGSLISSSFDKSYLSEEVPKQIWICWLQGMENAPELVKSCYRSLKKQ
                     FPEYVITVISSENISEYVEIPDIIYKKWGNGVIGNAHFSDILRVELLRKFGGIWIDST
                     VYCTGITTIETIEKNPFFMYKSLSSVEERISSSNWMIASVPNHPFMITMSTLLQSYWS
                     KEVIAIHYYLFHILFTIMIESLPELWQLVPTYTNATPHIMVDELNNIFSKERYQQLCQ
                     ISDFHKLNYKKNYNDKSESLYSHLLNQ"
     misc_feature    10827..11645
                     /gene="wciW"
                     /locus_tag="SPC18F_0013"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 1.8e-144"
     gene            11669..13126
                     /gene="wzx"
                     /locus_tag="SPC18F_0014"
     CDS             11669..13126
                     /gene="wzx"
                     /locus_tag="SPC18F_0014"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI33609.1"
                     /db_xref="GOA:Q4K128"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K128"
                     /translation="MPNLKKNIVYNVLYQILAVIVPFITSPYLARVLGAEQIGVYSFT
                     YSIAFYFMILSMLGISNYGNRTIAQVRTSREHLNQEFSNIYAVQLTCSLVMTVSYLIY
                     ATVFVNSFQIVAYIQVLHVLSYATDVSWFFYGLEEFRITVARNSFVKLLTLISIFTFV
                     KSPNDIYLYTFIMAGSTLLGQLITWPFLLKQVNFVRPSLGKIKKHMKPIIILFFPVLA
                     ISIFSFIDKIMLGMYSSLRETAFYENSDKIISIPKALIQAFGAVMLPRTVHLLSIGDE
                     QKSLEYVDKTMWVVLVITMGCAFGLAGVSATFAPVYWGEEFRASSQIIAGMTPALVFS
                     AFGNVIRTQFLIPRSFDKEYTVSLLYGAVVNILINILLIPKIGAMGAVIGIIVAELVL
                     CCYQTWIARNYLHIREYLINAGILFLIGSVMYMVLILISSILPTSLLTLIIEIIVGAF
                     IYISLLILYIFSSKNRVIIGLRTNFLEHTHLFKRK"
     misc_feature    11678..12481
                     /gene="wzx"
                     /locus_tag="SPC18F_0014"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.9e-56"
     gene            13129..14403
                     /gene="wzy"
                     /locus_tag="SPC18F_0015"
     CDS             13129..14403
                     /gene="wzy"
                     /locus_tag="SPC18F_0015"
                     /note="member of homology group 93"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33610.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q4K127"
                     /translation="MKFKFNPIAILYILLVYLELATDRQHLYPVTYMTKYYIGILIIV
                     LFVLLLVGRGKLIFVNKKLLYLAKILAIPTIVLFLYSVLLDVMNPVEFNGYFSRLSST
                     TIFGLLAIFQAIVVFQFFGQKVVDYTFTAISLSYLTSIIVAFRQGGLSQFILILTDDS
                     FNGSVLEMHEVAPITALFILYYLYKYFIKENSFSSVFHNILIALIILFLSLKRIVFLS
                     VLIIIPVFLVIYWYDKKVSKLGKERKILSLLNIFSLIFITGIFFYVYSVKSDFIYTFI
                     QEHNINSMARTDLWKGVESTYNFAPIFMGRGIGFVTKWMDNNWMTLNINGLTGSMGIH
                     NDILKYYIEIGFVGLFIYFYTLLYRNAKRIFVKIGHKESFIYFVLIMFQMLIWFTDNI
                     SIYHNFLWILNLLLFSLTNSDTELENLDFKNF"
     misc_feature    13966..14178
                     /gene="wzy"
                     /locus_tag="SPC18F_0015"
                     /note="HMMPfam hit to PF04932, O-Antigen Polymerase, score
                     2.1e-09"
     gene            14457..15458
                     /gene="wciX"
                     /locus_tag="SPC18F_0016"
     CDS             14457..15458
                     /gene="wciX"
                     /locus_tag="SPC18F_0016"
                     /note="member of homology group 107"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33611.1"
                     /db_xref="GOA:Q4K126"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4K126"
                     /translation="MKTDARTKKRENETLYILKVWATFSVIAIHFGFLGQIGVFYKVL
                     ARFAVPLFFMISGFYSFSISEEKLKKRIKNLSLLIISSTSFYFLLDVFLQLTQGNLRV
                     VFERFTFNNIFNFLVFNQISALIGSLATPLWFLYALLYVYIYLFFSNKKWIFNTILTV
                     IILCCSFIIELKANSALFYRNFLFMGVPFFSFGMYFAQIQRKIINYKHFKELFIIGIM
                     ISGFLTLIEYTFLGANFELYISSVIISCMLMVFSIKYPQLWTLDFAVNIAKKNATFIY
                     ISHQFVILLFKTYVRDGIAYKIGTFLIFLACVIMSIIFNYIVDIISRCCIKEKQDII"
     gene            15455..16615
                     /gene="wciY"
                     /locus_tag="SPC18F_0017"
     CDS             15455..16615
                     /gene="wciY"
                     /locus_tag="SPC18F_0017"
                     /note="member of homology group 78"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol phosphotransferase"
                     /protein_id="CAI33612.1"
                     /db_xref="GOA:Q4K125"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="UniProtKB/TrEMBL:Q4K125"
                     /translation="MKFYIKNLLKKVFTLPLHLLPIQSNKIIFDNFGGRGFGDNPKYI
                     LEELVSREKNLDLVWVTKDREISIPEGVRVVKYGSYRSFYEWLTARVWVDNIRNSDRP
                     WKRNGQIYLQTWHGSDGVKLIEKSVAGNLKKTYIRMAKYDGKITDGIVSSRHFQTLGM
                     QNNFWLTENVEFLEFGLPRNDDFFKSEKIKTTNIKFRTLFDIDLDELVVLYMPTFRDD
                     GSLNAYNLDYSKLIHVFQNKFRKNVRILVRFHPNVDSSFINLQDTDCINVSTYSNPQD
                     LMMSADVMITDYSSASIDFMLLNRPVFLYLPDYQSYVNDRPLDDNFDKLPFPRAYHNN
                     ELTEIIRDFERSKYDEKVRLYELEDVRFDRGKASVQCANWIEEKIKNNKVID"
     misc_feature    16040..16585
                     /gene="wciY"
                     /locus_tag="SPC18F_0017"
                     /note="HMMPfam hit to PF04464,
                     CDP-Glycerol:Poly(glycerophosphate) gl, score 8.2e-68"
     gene            16657..17049
                     /gene="gct"
                     /locus_tag="SPC18F_0018"
     CDS             16657..17049
                     /gene="gct"
                     /locus_tag="SPC18F_0018"
                     /note="member of homology group 28"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol-1-phosphate biosynthetic protein
                     Gct"
                     /protein_id="CAI33613.1"
                     /db_xref="GOA:Q4K124"
                     /db_xref="InterPro:IPR004820"
                     /db_xref="InterPro:IPR004821"
                     /db_xref="InterPro:IPR006409"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="UniProtKB/TrEMBL:Q4K124"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQLGDYLIVVVSSDEFNLKE
                     KNKVCYFNYEHRKNLVEAIRYVDLVIPETSWEQKKSDVKEYRIDTFVMGDDWKGKFDY
                     LEEEGVEVVYLPRTKEISTTKIKEDLSE"
     misc_feature    16669..17037
                     /gene="gct"
                     /locus_tag="SPC18F_0018"
                     /note="HMMPfam hit to PF01467, Cytidylyltransferase, score
                     3.9e-29"
     gene            17147..17691
                     /gene="HG94"
                     /locus_tag="SPC18F_0019"
                     /pseudo
     CDS             join(17147..17257,17319..17507,17518..17691)
                     /gene="HG94"
                     /locus_tag="SPC18F_0019"
                     /note="member of homology group 94"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein (pseudogene)"
     gene            17896..18765
                     /gene="rmlA"
                     /locus_tag="SPC18F_0020"
     CDS             17896..18765
                     /gene="rmlA"
                     /locus_tag="SPC18F_0020"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI33615.1"
                     /db_xref="GOA:Q4K123"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4K123"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGYEFGIKLSYAEQPSPDGLAQAFIIGEKFIGDDSV
                     ALILGDNIYHGPGLSKMLQKVSSKESGATVFGYHVKDPERFGVVEFDKDMNAISIEEK
                     PEHPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVEVMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    17899..18615
                     /gene="rmlA"
                     /locus_tag="SPC18F_0020"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 4e-119"
     gene            18766..19359
                     /gene="rmlC"
                     /locus_tag="SPC18F_0021"
     CDS             18766..19359
                     /gene="rmlC"
                     /locus_tag="SPC18F_0021"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI33616.1"
                     /db_xref="GOA:Q7BTQ6"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q7BTQ6"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     misc_feature    18802..19332
                     /gene="rmlC"
                     /locus_tag="SPC18F_0021"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 8.8e-16"
     gene            19372..20421
                     /gene="rmlB"
                     /locus_tag="SPC18F_0022"
     CDS             19372..20421
                     /gene="rmlB"
                     /locus_tag="SPC18F_0022"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI33617.1"
                     /db_xref="GOA:Q4K121"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K121"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    19387..20343
                     /gene="rmlB"
                     /locus_tag="SPC18F_0022"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 7.1e-05"
     misc_feature    19390..20130
                     /gene="rmlB"
                     /locus_tag="SPC18F_0022"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 2.7e-76"
     misc_feature    19390..20226
                     /gene="rmlB"
                     /locus_tag="SPC18F_0022"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0039"
     misc_feature    19393..20205
                     /gene="rmlB"
                     /locus_tag="SPC18F_0022"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.6e-05"
     gene            20487..21338
                     /gene="rmlD"
                     /locus_tag="SPC18F_0023"
     CDS             20487..21338
                     /gene="rmlD"
                     /locus_tag="SPC18F_0023"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI33618.1"
                     /db_xref="GOA:Q4K1G6"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1G6"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    20487..21335
                     /gene="rmlD"
                     /locus_tag="SPC18F_0023"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 4e-147"
     misc_feature    20490..21119
                     /gene="rmlD"
                     /locus_tag="SPC18F_0023"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.9e-19"
     misc_feature    20490..21131
                     /gene="rmlD"
                     /locus_tag="SPC18F_0023"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00013"
     misc_feature    20493..21221
                     /gene="rmlD"
                     /locus_tag="SPC18F_0023"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2.9e-08"
     gene            order(21401..21580,21584..22568)
                     /gene="glf"
                     /locus_tag="SPC18F_0024"
     CDS             join(21401..21481,21485..21580,21584..22249,22248..22568)
                     /gene="glf"
                     /locus_tag="SPC18F_0024"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI33619.1"
                     /db_xref="GOA:Q4K119"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K119"
                     /translation="MYDYLVVGAVFAHEAVLKGKKVKVIEKNHIAGNIYTREEEGIQV
                     HQYGAHIFHTSDKEIDYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNKLWGVVTP
                     AEAQAKIDEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGKPTTELPSFI
                     IRRLPVHLTYDNNYFNDTYQGIPIGGYNVIIENMLKDVEVELGVNFFANRQELEASAE
                     KVVFTGMIDQSFDYKHGELEYCSLRFDHEVLDEENYQGNAVVNYMDAETPYTRIIEHK
                     HFEFGGVKQRLSLLIEHSKTWEKGDEPYYPVNNDRNNHLYKSYKKLADEQGNVIFGGR
                     LGHYRYYDMHQVIGAALQCVRNELDSYSMKIKEQTRKLAVGCSKHCFEVADGS"
     misc_feature    order(21821..22248,22249..22424)
                     /gene="glf"
                     /locus_tag="SPC18F_0024"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 8.1e-107"
     gene            22802..>22849
                     /gene="aliA"
                     /locus_tag="SPC18F_0025"
     CDS             22802..>22849
                     /gene="aliA"
                     /locus_tag="SPC18F_0025"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33620.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K1C2"
                     /translation="MMKSSKLFALAGVTLL"
BASE COUNT     7478 a   3370 c   4535 g   7466 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggagaactgt ataaaaagca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attctcgaaa ttcaattaac tttacaaatt cccactattg aggagaaaga agatgaacat
      301 aaagaagcgt gtccttagtg caggcctgac ttttgcatct gttttgcttt tagttgcttg
      361 cggccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaactat ctattagact attacgctga taatatagtc aattgaaaca agagcaggat
      481 aaaaaagcct cgtaaaaggt attgcaactt ggtaatacct ttttgaggtg ctttttgata
      541 tgagcccatg ttttctcaat aggattgtat tcaggcgagt agggaggaag aggtaaaagt
      601 ttatgcccaa actcttcgca caagagttct agcttcccca ttctatggaa tcttacatta
      661 tccataataa taaccgatag tgtggttaat gttggtaaga gaaacttctg aaaccaagct
      721 tcaaaaaagt cgctcgtcat cgtctcttcg taagtcattg gagcgattaa ctcaccattc
      781 atttgttaga cctgcaacca aagaaatcct ctgatatctt cttccagata ctttgcctct
      841 tcttaactga ccttttaatg agcgaccata ttctcgataa aaataagtat cgaatcctgt
      901 ttccaatata aacaggtgct aggtgcttta aactattaaa attcttaaga aataaggcta
      961 ctttttctgg ctcttgttca tagtaggtgt ggttcttttt ttcgagtgta gcccatagct
     1021 ttgagtgcat agtggatggt agttggatga cagccaaatt cagaagctat ttcagtcaaa
     1081 taagcgtctg gattatcagt aagatagttt ttaagtctat ctctatcaac ttttcttggt
     1141 tttgttcctt ttacttggtg gtttagctct cctgttttct cttttagctt taaccagcca
     1201 taaatggtat tacgtgagat ttggaaaacg tgtgatgctt ctgttatact acctgttcgc
     1261 tcacaataag agagaacttt tttacgaaaa tctattgaat atgccataag aagattatac
     1321 cacattgtgt actataatta tattgaaact agaatagtac gcctctgctt ctaaaacatt
     1381 gttagaaatc gatttgactg tcctgatcga tttgtcatgt tcttatttca ttttactata
     1441 tttttggttc gcgggaagtc tactaagata cttaaagatg cagatagtga aaaaaaggtg
     1501 tagacattac cgtaaaaaag tgatataatc gtatgatgtt caatgtatag gtgttaatca
     1561 tgagtagacg ttttaaaaaa tcaggttcac agaaagtgaa gcgaagtgtt aatatagttt
     1621 tgttgactat ttatttattg ttagtttgtt ttttattgtt cttaatcttt aagtacaata
     1681 tccttgcttt tagatatctt aatctagtgg taactgcgtt agtcctacta gttgccttgg
     1741 tagggctact cttgattatc tataaaaaag ctgaaaaatt tactattttt ctgttggtgt
     1801 tctctatcct tgtcagctct gtgtcgctct ttgcagtaca gcagtttgtt ggactgacca
     1861 atcgtttaaa tgcgacttct aattactcag aatattcaat cagtgtcgct gttttagcag
     1921 atagtgagat cgaaaatgtt acgcaactga cgagtgtgac agcaccgact gggactgata
     1981 atgaaaatat tcaaaaacta ctagctgata tcaagtcaag tcagaatacc gatttgacgg
     2041 tcaaccagag ttcgtcttac ttggcagctt acaagagttt gattgcaggg gagactaagg
     2101 ccattgtcct aaatagtgtc tttgaaaaca tcatcgagtc agagtatcca gactacgcat
     2161 cgaagataaa gaagatttat accaagggat tcactaaaaa agtagaagct cctaagacgt
     2221 ctaagaatca gtctttcaat atctatgtta gtggaattga cacctatggt cctattagtt
     2281 cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa tcgagatacc aagaaaatcc
     2341 tcttgaccac aacaccacgt gatgcctatg taccaatcgc agatggtgga aataatcaaa
     2401 aagataaatt aacccatgcg ggcatttatg gagttgattc gtccattcac accttagaaa
     2461 atctctatgg agtggatatc aattactatg tgcgattgaa cttcacttct ttcttgaaaa
     2521 tgattgactt attgggaggg atagatgttc ataatgatca agagttttca gctctacatg
     2581 ggaagttcca tttcccagta gggaatgtcc atctagactc tgagcaagct ttaggttttg
     2641 ttcgtgagcg ctactcccta gcagatggcg atcgtgaccg tggtcgcaac caacaaaagg
     2701 tgattgtggc tatccttcaa aaattaacgt caaccgaagc gctgaaaaat tatagtacga
     2761 tcattgatag cttgcaagat tctatccaaa caaatatgcc acttgagacc atgataaatt
     2821 tggtcaatgc tcagttagaa agtggaggga attataaagt aaattctcaa gatttaaaag
     2881 ggacaggtcg gacggatctt ccttcctatg cgatgccaga tagtaacctc tatgtgatgg
     2941 aaattaacga cagtagcctt gcatctgtca aaactgctat tcaggacgtg ttggagggca
     3001 gatgaaatga ttgatattca ttcgcacatt gtctttgatg tagatgatgg tcccaagtca
     3061 agagaggaaa gcaaggctct cttgacagaa gcctacaggc agggggtgcg aaccattgtc
     3121 tctacctctc accgtcgcaa gggcatgttt gaaactccag aagagaagat agcagaaaac
     3181 tttcttcagg ttcgggaaat agctaaggaa gtcgcgagtg acttagtcat tgcttatggg
     3241 gctgaaattt actacacacc agatgttttg gataagctgg aaaaaaatcg gattccgacc
     3301 ctcaataata gtcgttatgc cttgatagag tttagtatga acacccctta tcgcgatatt
     3361 catagtgcct tgattaaaat attgatgttg ggaattactc cagtcattgc ccacatcgag
     3421 cgctatgatg cacttgaaaa caatgaaaaa cgcgttcgag agctgatcga tatgggctgt
     3481 tacacgcaag taaatagttc acatgtcctc aaatccaaac tttttggaga acggtataaa
     3541 ttcatgaaaa aaagagcgca gtatttcttg gagcgtgatt tggttcatgt gattgcaagt
     3601 gatatgcata atgtggacag cagacctccc catatggcag aagcatatga ccttgtttct
     3661 caaaaatacg gagaagcgaa ggctcaggaa ctttttatag ataatcctcg aaaaattgta
     3721 atggatcaac taatttagga gaaataatga aagaacaaaa tacgatagaa atcgatgtat
     3781 ttcaatcact taaaacctta tggaaataca agctaatcat tttattagtg gcacttgtga
     3841 caggggcggg agcttttgca tatagcactt ttattgttaa gccagaatat acaagtacca
     3901 cgcgtattta cgtagtcaac cgtaatcaag gagataagcc gggactgacg aatcaggact
     3961 tgcaggcagg aacttatctg gtaaaagact accgcgaaat tatcctttcg caagatgtat
     4021 tggaaaaggt agcgacaaat ttgaaattgg atattccagc aaaaacgtta actagcaaag
     4081 tgcaagtgac tgtaccagcc gacactcgta tcgtctcaat ctctgtcaag gataaacaac
     4141 cagaggaagc cagtcgcatt gctaattctc tacgagaagt tgctgcagaa aagatcatcg
     4201 ctgtaacgcg agtatctgat gtaacgacgc ttgaagaagc gcgaccagct acgactccct
     4261 cttctccaaa tgttcgacgc aacaccttag ttggttttct tggaggagcc gccgtaacag
     4321 taattactgt tcttttgatt gagttgctcg atacccgtgt aaaacgtcct gaagatgttg
     4381 aagatgtact gcaaatgcca cttctaggag tcgttccaga ttttgataaa atgaaatagg
     4441 aggaagttat gccaacgtta gaaatctcac aggtgaaatt agaacttgcg aaaaaggcag
     4501 aggaatatta taatgctttg tgcacgaacc tacagttaag tggagatgat ttgaaagtat
     4561 tttctatcac ttctgtgaaa gcaggagaag gaaaaacaac gacttccacc aatatcgctt
     4621 gggcttttgc gcgtgcaggt tacaaaacgc tgctgattga tgcagacatg cgtaactccg
     4681 ttatgtcagg tgtctttaaa tcaagggaaa ggattactgg actaacagaa tttctatcag
     4741 ggacaacaga cctgtcacag gggctttgcg ataccaatat tgagaatctc tttgtgattc
     4801 aggctggctc tgtgtcacca aatccgacag cccttcttca aagtaagaat ttcagcacaa
     4861 tgcttggaac cttgcgtaaa tattttgatt atatcattgt tgatacacca cctattggaa
     4921 ttgttattga tgcggcaatt atcactcaaa agtgtgatgc gtccatcttg ataacagcaa
     4981 caggtgaggt gaataaacgt gatgtccaaa aagcgaaaca acaattagaa caaacaggga
     5041 aactgttcct gggagttgtt ttaaataaat tggatatctc ggttgataag tatggagctt
     5101 acggttccta tggaaattat ggcaaaaaat aacttagaaa agattttatg gatgaaaaag
     5161 gattgaaaat ttttctggca gtattgcaga gtattattgt cattttattg atttattttc
     5221 ttagctttgt tagagagaca gaacttgaac gttcttcgat ggttatacta taccttctcc
     5281 acttttttgt attttatttt agttcctatg gtaacaattt ttttaaaaga gggtacctag
     5341 ttgagtttaa tagtactata agatatattt ttttctttgc aatagctata agtgtattaa
     5401 acttttttat agcggaacgg tttagtatct ctagaagagg aatggtatac ttcttaactt
     5461 tagaaggaat atccttatac ttgttaaatt tcttagtaaa aaaatattgg aagcatgtgt
     5521 tttttaatct aaaaaatagc aagaaaattt tactgttaac agtaacgaaa aatatggaaa
     5581 aagttcttga taaattgcta gaatctgatg aactttcatg gaaattggta gcagtaagtg
     5641 ttttggataa atctgatttt caacatgata aaatacctgt aattgaaaag gaaaaaatta
     5701 ttgaatttgc aacgcatgaa gttgtggatg aggtgtttgt caatcttcca ggagagagct
     5761 acgatattgg agaaattatc tctaggtttg agacaatggg gatagatgta actgtaaatc
     5821 ttaaagcatt tgataaggat tttggtcgca ataaacaaat tcatgagatg gtaggattgg
     5881 atgtagtcac tttctctaca aatttttata aaactagtca tgtgatttca aagagaattc
     5941 tcgatatttg tggtgccact attggcctta ttctttttgc tatagctagt ctagttttag
     6001 ttccattgat tcgtaaagat ggcggaccag ctatttttgc tcaaactcgt atagggaaaa
     6061 atggtcgaca ttttaccttt tataaattcc gttcgatgcg gatcgatgct gaatctatca
     6121 aagaacagtt gatggatcaa aatacgatgc aaggtggtat gtttaagata gacaatgatc
     6181 ctcgtgttac aaaaattggt cgctttattc gtaaaaccag tttagatgag ttaccccagt
     6241 tttggaatgt atttatagga gatatgagtt tggtgggaac acgtccacct acagtagacg
     6301 agtatgatca gtatactcca gaacagaaac gtcgactcag ctttaaacct ggtattacag
     6361 gtttatggca ggttagcggc cgtagtaaaa taaccgattt tgacgatgtt gtaaaattag
     6421 atgtggctta tattgataat tggacaatct ggaaagatat tgaaattttg cttaaaactg
     6481 ttaaagttgt atttatgaga gatggagcga agtaatttct gtatatccat catattagga
     6541 gagaaatgaa aaagtcagtt tatatcattg gttcaaaagg aattcctgct aagtatggag
     6601 gatttgaaac ttttgttgaa aaattaacag ccttccaaca agataaggct atccaatatt
     6661 atgtggcttg tatgcgtgaa aactctgcaa aatcagggac tactgaggat gtttttgaac
     6721 ataatggtgc tatctgttat aacgtcgatg ttcctaatat tggtccagcg cgagccatag
     6781 tatatgatat cgcggcaatt aacagagcta ttaaaattgc caaagaaaat aaggatgaag
     6841 atccaatctt ctatattcta gcttgtcgaa tcggtccgtt catccatgga attaagaaaa
     6901 aaatccagga gataggtggg actcttctag ttaatccaga tggtcacgag tggttacgag
     6961 ctaagtggag cgctccagtt cgtcgttatt ggaaaatttc cgaaggtctt atggtcaaac
     7021 atgcagatct tttagtgtgt gatagtaaga atattgaaaa atatatccaa gaagattata
     7081 aacagtatca acctaagaca acctatatcg cttatgggac tgatacaaca cgctccatat
     7141 taaagagtag tgacgaaaaa gtacgttctt ggttcaaaaa gaagaatgtt tctgaaaacg
     7201 agtattacct agttgtagga cgttttgttc cagaaaataa ctatgaggct atgatacgtg
     7261 ggtttttagc atctaattct aagaaggact ttgtcctaat aacaaatgta gaacagaata
     7321 aattttataa tcaactatta gcaagtactg gctttgataa agatccacga gtgaaatttg
     7381 ttggaacagt ctacgatcaa gaacttctga agtatattcg agaaaacacc tttgcttact
     7441 tccatggaca tgaagttgga ggaaccaatc cttcgctttt agaagctctg gcatcaacta
     7501 aactgaattt attgctagat gttggcttta accgagaagt tggggagcaa agtgcaatct
     7561 attggaaaaa agatgagctt tcccaagtaa tcgagaaagt tgaacaattt gatgcaaaaa
     7621 tgattgatga gttagataga caatcaaatc agagaattgt ggattttttc acttgggaaa
     7681 agattgtcac agactacgag aaattattta aaaaatgaaa atattacatt atactttagg
     7741 atttcaaccc cagcgaacag gtggtttggt taaatatgct gaggatttaa tgctagagca
     7801 aattgctcaa ggttatcaag tggctgccct atatccagga agaattaagt tcttttcaaa
     7861 aaaaatagaa ataattaaag cgacgtcaag acagtttgag tgttatgagc tgcttaatag
     7921 cttacctatg gctttatttg gaggtatatc cgatccaact gctttcctga caccttgtga
     7981 caaaaatgtt tatcgtactt ttttagaaaa agtacaaccc gacattatac atattcactc
     8041 gtttatggga ttgcataaag aattcctcga aattgctaaa aacttgaata ttagagtggt
     8101 ttttacgagc catgattatt atggattagc acccgtacct catttctatt ttaatggggt
     8161 ggattatagt gataaaagta caaacttaac atggaatatt atgtcttcca atgctttaag
     8221 tgtgaaaaaa ctaagacttt ttcaggtttc attttatcct actattcgta aacttttgaa
     8281 actattaggg aaaaatccaa aatctaaaaa gaatttagtt attcgagatg ttattgagga
     8341 gcaagattat agtgagcttc gatactatta taatgagatg tttcacttaa tagatggtta
     8401 tttgtttaat agtagacttg caaagaaggt atatgagata aatgagatta agtcagctaa
     8461 tagtatagta ttatctataa caaatagttc aattaatcat catcagagat tgacaactac
     8521 aaataataaa attagagttg cttatattgg tccagatgaa gaatataaag gatattttga
     8581 ttttgttgac tttgttgaaa ctttagatcg agagtcctat gaagtggcaa cttatggcca
     8641 tttaccaaat gaagagtgtc cttcattcat tgaacaaaaa ggatatttta ctaaggaaat
     8701 gattgacagt gtctatgaaa atattgatat tcttattgtt ccaagtaagt ggaaggaaac
     8761 atttggattg ataacagtag aagcattatc ctatggggta aatgttttcg tgagtgaaaa
     8821 tgttggatca aaagacttac ttccagaatc gcatgttttt aaaaatcaga atgatttagt
     8881 agttaaattt ttaaaaaatg atatagaaaa tacaaaattg aaaactttag atgaacactc
     8941 gatagaagtg attcagtatt atgaaagagt gataaatgat agttaagagt ttcataaaaa
     9001 agattactgg aaaaacagta gacattcatc cagatgtacc tttgtcgtat atactacaaa
     9061 gaggtataaa ctatggtttc ggactctttc gtggggttgt acgtggaatc ggatttggtc
     9121 aaaacgacaa acgtttattc attggacaag gagtttctat cttagcaaag cgtaaattat
     9181 ttgttggaaa aaatgttcga attggtaaaa aggtgtctat agatgcactg tcaaaagaag
     9241 gaatccattt tgcagataat gtaaagattg gagattattc tcaaattatt ggcacaggtt
     9301 ctataaaaaa tatggggatt ggcttgaaaa tcggtaagaa ttcatctttt tcagaatata
     9361 gtttatttgg ttctgctgga ggtatcacaa ttggtgataa tgttatcgca ggtcagaatg
     9421 ttcgttttca tgctgaaaat cataattata gtgatttaga taaactcatt gttgaacaag
     9481 gggtatctcg aaagggaatt tcagtaggtg ataattgttg gattggtgct ggatctgttt
     9541 ttttggatgg gtccagcatc ggttcaggtt gtgttgttgg agcgaatgct gtcgtcacta
     9601 agcagtttcc agataatgtt atcataggtg gagtaccagc taggatactg gcctatagat
     9661 agtgtttaac tatttctgaa aggaagaaaa tttatgccta catttagtgt agttgttcca
     9721 gtttataatg tagagaatta tttatcgcaa tgtttaaatg ctcttgtaaa tcagtctttt
     9781 aaagattttg aacttatctt ggtaaatgat ggttctactg acacatctgg aagtctttgt
     9841 gaagaatggg gaaaaaaaga tcatcggata aaagtaatac ataaaaccaa tgaaggtctt
     9901 ggttttgcac gtaacacagg tattgaaaac tgtacaggag attatattgt ctttgttgat
     9961 tcggatgatt atgtctcata tgagatgctt gaaatttatg atacatactt acaacgtttt
    10021 aatgcagacg tgatttatag tgaaaatttt tatcgagtgg ataataaagg aaatattata
    10081 gaaccacttg atcagagcct agattccatt ttttataaaa atgattcaat tttcacagaa
    10141 cttttaccag atgtaatatc ttcaccacca gaatttattg gagatggaaa gataggtgtt
    10201 tcagtgtgga aaggggtata taaacgttct ttgtttaagg ataaggggct attatttcat
    10261 tcagaaagag aattcatttc agaagatgct atttttcaaa ttgattgttt aaaattagca
    10321 atatctgccc ttgttatccc agatatttta tattactatc gtgaaaactt tggttcttta
    10381 agtatgaaat ataaagaaga tcggtttgag ttgaataaaa tcttgtataa cgagcaatta
    10441 aaaagagttg aggggttacc taatcaagaa attttggaag aaagaattga gagaatttta
    10501 attgctaata ttcgtttatg tatctttcag gaatccttat ataaaaattc tagaattcat
    10561 aaacgtttgc aaagaattag acagatttgt aaggacccaa tatcaaaatc agtattacgt
    10621 cattatccaa tccgtcgttt acctttttct aaacgcttga tctgcgtatt agctaagtat
    10681 aatatgccgt tgatgctttt agttttaacc ttattaaaat atcggaatcg gagcgtataa
    10741 cttttatggg gatgaatata gaaaaattaa aactatcttt gaaaaatgga acgttttttt
    10801 ctgttgttat tcacgcctta cgaaatcgtt ggcctttatg gtggattggg aacaaggcta
    10861 ttcgagaagt gcaacttgaa gatagggcct acagaatact aaaaaagaaa tacggctcct
    10921 taatttcaag ctcttttgat aaatcatatt tatcagaaga agttcccaag caaatctgga
    10981 tttgttggct tcaaggtatg gagaatgctc cagagttggt gaaatcatgt tatagatcac
    11041 taaaaaaaca atttcctgaa tatgtcatta cggttatttc ttcagaaaat atttccgaat
    11101 atgtagaaat acctgatatt atttataaaa aatggggaaa tggtgtaata ggaaatgctc
    11161 atttttctga tatccttcgg gtagagctgt tacgtaagtt tgggggaata tggattgact
    11221 caacagtgta ttgtacagga attactacca tagagacaat tgaaaaaaat ccatttttta
    11281 tgtataaaag tttatcttca gttgaggaga gaatttcctc ttccaactgg atgattgctt
    11341 ctgttcccaa tcatccattt atgattacga tgagcacact cttgcaatct tattggtcaa
    11401 aagaagttat agcaattcat tattatctat ttcatattct ttttacgatt atgattgaat
    11461 cacttcctga gttgtggcag cttgtaccca cctatacgaa cgcaacacca catataatgg
    11521 ttgatgaatt aaataatatt ttttcaaagg aacgttacca gcaattgtgt caaatttcag
    11581 attttcataa attaaattat aaaaaaaatt acaatgataa atcagagagt ttgtacagtc
    11641 acttactgaa tcagtagagg ggagaatctt gcctaattta aagaaaaaca ttgtttacaa
    11701 tgtcttatat cagatcttag ctgtaatagt accgtttatt acctcacctt acttagcgcg
    11761 tgtgttaggt gcagagcaaa ttggagttta ttcttttact tattccattg ctttttactt
    11821 tatgattctg tccatgttgg gaatttctaa ttatgggaat cggacaatag cacaggtacg
    11881 aacaagtaga gaacatttga atcaagaatt ttcgaatatt tacgcggttc aattgacgtg
    11941 ttcactagta atgaccgtct catatttgat ttatgcaaca gtatttgtga atagttttca
    12001 gattgtagcc tatatccaag tattacatgt tttatcgtat gcaacagatg ttagttggtt
    12061 tttttatggt cttgaagagt ttcgtattac ggttgctagg aattcatttg ttaagttatt
    12121 aactttaata tctatcttta catttgtaaa aagccctaat gatatctatt tatatacctt
    12181 tataatggca gggagtaccc tgcttggtca gttgattaca tggccatttt tgctaaaaca
    12241 agtaaacttt gtgcgcccta gtcttggaaa aataaagaaa cacatgaaac ctattattat
    12301 tttatttttt cccgtcttag cgattagtat tttttcgttt atagataaaa taatgcttgg
    12361 gatgtatagt agtttgaggg aaactgcttt ttatgagaat tcagataaga tcattagtat
    12421 tccaaaagct ctgattcaag cctttggagc tgtaatgttg cctcgaacag tacatttact
    12481 gagtataggt gatgaacaaa aaagtttaga atatgttgat aaaacgatgt gggttgtttt
    12541 agtgattaca atgggctgtg ctttcggttt agcaggagtt tctgcaacct ttgctcctgt
    12601 ttattggggt gaagaattta gggccagtag ccaaattatt gcaggaatga caccggcttt
    12661 agtattttcg gcttttggaa atgtcatccg aacccagttt ttaattccac gaagttttga
    12721 caaggaatat acggtatctt tgctttatgg agccgtagtt aatatcttga ttaatattct
    12781 tttgattccg aagataggag caatgggagc tgttatcgga ataattgttg cagagttagt
    12841 tctatgttgc tatcaaacgt ggattgctag aaattattta catatcagag aatatctgat
    12901 aaatgctggg atattgtttc ttattggttc agtaatgtat atggttttaa ttcttatttc
    12961 aagtatttta cctacatcgt tacttacact tattattgaa attatagtcg gagctttcat
    13021 ttatattagt ttactgattc tgtatatctt ttcttcaaaa aacagggtaa ttattggttt
    13081 acgaacaaat tttttagaac atactcattt atttaaaagg aagtaatagt gaaatttaaa
    13141 tttaatccaa tcgcgatact gtatatattg ctagtatact tagagttggc tacagatagg
    13201 caacatctgt atcctgtaac gtacatgaca aaatattata ttggtatttt aattattgtg
    13261 ttgtttgttt tattattagt aggccgtggg aagcttattt ttgttaataa aaaattatta
    13321 tatcttgcta agatattagc tataccaaca attgttcttt tcctgtactc agtcttacta
    13381 gacgtaatga acccagttga atttaatgga tattttagta ggttatcaag tacgactatt
    13441 tttggtttgt tagctatctt tcaagctata gttgtttttc aattttttgg acaaaaagta
    13501 gtagattaca cttttacagc tatctccctc agctacttaa ccagtatcat tgttgccttt
    13561 aggcagggag gacttagtca atttatcttg atactaacag atgatagttt caatggttcg
    13621 gtactagaaa tgcatgaagt tgcacctatt acagccctct ttattctgta ctatttgtac
    13681 aaatatttta taaaagaaaa tagtttttct tcagtatttc ataatatctt aatagctctc
    13741 attattcttt ttttaagcct taaacgaatc gtttttttga gtgtattaat tatcatacca
    13801 gtatttttgg taatttattg gtatgataaa aaagtaagca aactagggaa agaacgaaaa
    13861 attttaagtt tattaaatat cttttcctta atatttataa caggaatatt cttttatgtt
    13921 tatagtgtaa aatctgattt tatatataca tttattcaag aacataatat taattcgatg
    13981 gctagaacag atttatggaa gggagttgaa tcaacctata atttcgcccc tatatttatg
    14041 gggagaggga tagggtttgt aacaaaatgg atggataata attggatgac tttgaatatc
    14101 aatggtctta caggatcaat ggggatccat aatgatattt tgaagtacta cattgagata
    14161 ggatttgtag gattatttat ttatttttac actcttcttt atagaaatgc taaacgtata
    14221 tttgtaaaaa ttggtcataa agaatcattc atatattttg tattgataat gtttcagatg
    14281 ctgatatggt ttacagataa tatttcaatt taccataatt ttttatggat cctaaatcta
    14341 ctactctttt ctttaactaa ttcggataca gaattggaaa atttagattt taaaaatttt
    14401 taatgtgtaa gtagtaacta ctaattttat taaaaaatca gaatataggt gtatttatga
    14461 agacagatgc taggactaaa aagagagaga atgaaacgtt atatattcta aaagtttggg
    14521 caacatttag tgtgattgct atacattttg gttttttggg ccaaattgga gtgttttaca
    14581 aagtattagc tcgatttgct gtacctttat ttttcatgat ttcaggattt tattcgttta
    14641 gtatttcaga agaaaaactg aagaaaagaa ttaaaaatct gagtttattg ataatttcca
    14701 gtacaagttt ttatttttta ctggatgttt ttcttcaatt aacacaagga aatctaagag
    14761 ttgtatttga aagatttact tttaataata tttttaattt tttggtattc aatcaaattt
    14821 ctgctctaat tggctcgtta gcaacaccac tatggttctt atatgcatta ctgtatgttt
    14881 atatttatct atttttttca aataaaaaat ggatatttaa tactatcttg actgtgatca
    14941 tactctgttg ttcatttata atcgagttaa aagcaaatag tgctttattt tatagaaact
    15001 tcttatttat gggagttccc ttcttttctt ttgggatgta ttttgctcaa attcagagaa
    15061 aaattataaa ttataagcac ttcaaagaac tttttataat tggaattatg atttcaggat
    15121 ttctaactct gattgaatat acctttttag gagcaaattt tgaactttat ataagttcgg
    15181 tgataatatc ttgtatgctt atggtctttt cgattaaata tcctcaactc tggacgctag
    15241 attttgctgt caatattgct aaaaaaaatg cgacgtttat ttatattagt catcaatttg
    15301 tgattttatt atttaaaaca tacgttaggg atggaattgc ttataaaatt ggaactttct
    15361 tgatattttt agcatgtgtt attatgagta ttattttcaa ctatatagtc gatataatca
    15421 gtcgttgttg cataaaagaa aaacaagata taatatgaaa ttttatataa aaaatttact
    15481 aaaaaaagtc tttacattac cgttgcattt attgcctatt cagtctaata agataatatt
    15541 tgataatttt ggtggtagag gttttgggga caatcctaag tatatacttg aagaacttgt
    15601 ctctcgagaa aagaatctag atcttgtgtg ggtaacaaaa gatagagaaa tttctatccc
    15661 tgaaggcgtt cgagtagtaa aatacggcag ttaccgttct ttttatgaat ggttaacagc
    15721 tagagtttgg gtagataata ttcgtaattc tgatcgacct tggaagcgaa acggacagat
    15781 ttatcttcaa acttggcatg gttcagatgg ggtaaagtta attgaaaaaa gtgttgcagg
    15841 gaacctaaaa aaaacatata ttagaatggc gaagtatgat ggaaagatta cagacggtat
    15901 cgtatcaagt cggcactttc aaactttggg tatgcaaaat aatttttggc tgacagagaa
    15961 tgtggaattt ctggaatttg gattacctcg aaatgatgat ttttttaaaa gtgaaaaaat
    16021 caaaaccaca aatataaaat ttagaacatt atttgatatc gatttagacg aactggtagt
    16081 tttgtatatg ccgacgttca gagatgatgg atcgttgaat gcctataatt tagattactc
    16141 gaaactaata catgtttttc aaaataaatt tagaaaaaat gtaagaatat tagttcgttt
    16201 tcatccaaat gttgattcta gttttataaa tttacaggat acagactgta taaatgtgtc
    16261 gacctattca aatcctcagg atctgatgat gagtgcggat gtgatgatta cggattattc
    16321 atcggcttct attgatttta tgttattaaa tcgtccagta tttctgtatt taccagatta
    16381 tcaaagttat gtgaatgata gaccattgga tgataacttt gataaattgc catttccaag
    16441 agcatatcat aacaatgagt tgacagaaat tattagagac tttgaaagaa gtaaatatga
    16501 tgaaaaagtt cgtctgtatg aattagagga tgttcgtttt gatagaggaa aagcatcagt
    16561 acagtgtgct aattggattg aagaaaaaat aaaaaacaat aaagttattg attgaaataa
    16621 ttatatttat tgaatgataa ataaggaggc ctttagatga aaagagttat aacatatggt
    16681 acatttgatt tattgcatta tggtcatatc aatcttttga aacgtgctaa acagctaggt
    16741 gattatttga ttgtagttgt ttcaagtgat gagtttaatt taaaagaaaa gaataaagta
    16801 tgttacttta actacgaaca cagaaaaaat ttagtagaag ctattcgata tgtcgattta
    16861 gtaatccctg aaactagttg ggaacagaaa aagtcagatg ttaaagagta ccgtattgac
    16921 acttttgtaa tgggtgatga ttggaaaggt aaatttgatt atcttgaaga agaaggtgtt
    16981 gaagtagtct atttgcctag aacaaaggaa atatcaacca caaagataaa agaagattta
    17041 tcggaatgaa atattattaa aaaatgctga cataagaaat tgtgactttt gtgtctagtt
    17101 tttgatagaa taaagtaaca acactttaac caatgaggtg tgaataatgg tagtaatttt
    17161 taaagatgta cttgttgaag agaaaactga tgaagaaaaa caacatattt tatctatttt
    17221 aaatgatgag aatgttagag cttttgattg tggatattaa gaattgaatg atgttttttg
    17281 atatttagaa caaatacgat gaagaaacag gccatgtatt gcctattgta aatcaaaatt
    17341 ttgaattatt aggttttatt tcttgtagac tagtatcatt ttctttcata gctcaggtta
    17401 aagagatggg aattagcata gattatcttg gtattcataa ggattgccag aaaatgggtg
    17461 atcggttcgc ttttggtgct ctttgcgctt cgattatctt taactattga ctgttgatta
    17521 ccaataaaag gtgtaatagt tcatgctttc gaggatgttg tagaattcta tgacaaactg
    17581 ggttttattg accctagaga tatagtgatt tataatggca aaccggttac tatatatttt
    17641 agtattgaaa aactaagaaa tggtgaaaat tattcctctc acacagttat ttgaaacatc
    17701 cttagaaaat gatttttaat tgtatgcaaa caaagtagaa ttcgcttatt tcatcttatg
    17761 ctaaatgtaa tatgaaacaa gtgaattttt atagataaag aagaatttta aaaaatgtga
    17821 tgattatttt ctttttagag cagtacagaa ttaatagtaa ttgactctaa atcaataaag
    17881 aaaggtaccc cttttatgaa aggtattatt ctagcaggtg gttcgggaac tcgcttgtat
    17941 cctttgactc gcgctgcatc aaaacaactt atgccggttt atgataaacc gatgatttac
    18001 tacccacttt caacattaat gttggctggg attagggata ttttgattat ctcaactcct
    18061 caagatttgc ctcgttttaa agagcttctt caagatggtt atgagtttgg tattaaactt
    18121 tcttatgctg agcaaccaag tccagatggt ttggcacaag cctttatcat tggggaaaag
    18181 tttattggtg atgatagtgt tgcgctaatc ttaggcgaca atatctacca tgggcctggt
    18241 ctttctaaga tgctacaaaa ggtatcaagt aaggagtcgg gagcaactgt ttttggctac
    18301 catgtcaagg atccagagcg ctttggtgta gttgagtttg acaaggatat gaacgctatt
    18361 tctatcgaag aaaagccaga gcaccctcgt tcaaactatg cagttacagg actctatttc
    18421 tatgataatg atgtagtaga gattgccaaa agtataaaac caagccctcg tggtgaactg
    18481 gaaattacag atgtaaacaa ggcttaccta gatcgtggag atttatccgt tgaggttatg
    18541 ggacgaggct ttgcttggct ggatactgga actcatgaaa gtttattaga ggcttcacag
    18601 tacatcgaga cagtgcaacg gatgcaaaat gttcaggtgg caaacttaga agaaattgcc
    18661 tatcgcatgg gttatatcag tcgtgaagat gtattgacct tagctcaacc acttaagaaa
    18721 aatgaatacg gacagtatct gctccgtttg attggagaag catagatgac agataatttt
    18781 ttcggtaaga cgcttgcggc acgcaaggtt gaagctattc caggcatgtt ggagtttgat
    18841 atccccgttc atggagataa tcgtggctgg tttaaagaaa atttccaaaa ggaaaaaatg
    18901 cttccacttg gatttccaga gtctttcttt gcagaaggaa aattgcaaaa caatgtatcc
    18961 ttctcacgta aaaatgtcct tcgagggctc cacgcagagc cttgggataa gtacatctct
    19021 gtagcagatg gagggaaagt tctgggttct tgggttgatc tacgcgaggg tgaaaccttt
    19081 gggaatacct atcagacagt aattgatgca agcaagggaa tctttgttcc tcgaggcgta
    19141 gctaatggct tccaagttct atcagataca gtgtcatata gctatctggt caatgattac
    19201 tgggctctcg agctcaaacc caagtatgcc tttgtgaact acgctgatcc aagccttggt
    19261 attgaatggg aaaatattgc agaagcagag gtttcagaag cagataaaca tcatccccta
    19321 cttaaggatg taaaaccttt gaaaaaagaa gatttgtaaa aaggaaagaa tatgactgaa
    19381 tacaaaaata ttatcgtgac aggtggagct ggctttatcg gttctaactt tgtccattat
    19441 gtttacgaga actttccagg tgttcacgtg acagtcctag ataagttgac ttatgctgga
    19501 aatcgcgcga atattgagga aattttaggt aatcgtgttg agttagttgt tggtgacatt
    19561 gctgatgcgg agttggtaga caagttggct gctcaagcag atgctatcgt tcattatgca
    19621 gcggaaagcc acaatgataa ttcgctcaat gatccatcgc catttattca tactaacttc
    19681 atcggaacct atactctttt agaagctgct cgtaagtatg atattcgctt ccaccatgta
    19741 tcgacagatg aagtttatgg ggatctccct ttacgcgaag atttgccagg tcatggtgaa
    19801 ggaccaggtg agaaatttac tgctgaaaca aaatacaacc caagctctcc gtactcatca
    19861 accaaggcag cctcagattt gattgtcaaa gcctgggtgc gttcttttgg agtcaaggca
    19921 acgatttcca actgttcaaa taactacggt ccttatcaac atatcgaaaa attcatccca
    19981 cgtcagatta ctaacatcct aagtggaatt aagccaaaac tttacggtga aggtaagaat
    20041 gttcgtgact ggattcatac caatgaccat tcttcaggag tttggacaat cttgacaaaa
    20101 gggcaaatcg gtgaaaccta cttgattggg gctgatggtg agaagaacaa taaggaagtt
    20161 ttggaactta tccttaagga aatgggacaa gctacggatg cctatgatca tgtgactgac
    20221 cgtgcaggac atgaccttcg ctatgcgatt gatgccagca agctccgtga tgagttgggg
    20281 tggaaacctg aatttaccaa ctttgaagct gggctcaagg caacaatcaa gtggtataca
    20341 gataaccaag aatggtggaa agcagaaaaa gaagctgttg aagccaatta tgctaagact
    20401 caggagatta ttacagtata aaaagcagga aatagctgct ttttattgct atattgggaa
    20461 gagttacata ttagaaaggt ctagagatga ttttaattac aggggcaaat ggccaattag
    20521 gaacggaact tcgctattta ttggatgaac gtaatgaaga atacgtggca gtagatgtgg
    20581 ctgagatgga cattaccaat gaagaaatgg ttgagaaagt ttttgaagag gtgaaaccga
    20641 ctttagtcta ccattgtgca gcctacaccg ctgttgatgc agcagaggat gaaggaaaag
    20701 agttggactt cgccatcaat gtgacgggga caaaaaatgt cgcaaaagca tctgaaaagc
    20761 atggtgcaac tctagtttat atttctacgg actatgtctt tgacggtaag aaaccagttg
    20821 gacaagagtg ggaagttgat gaccgaccag atccacagac agaatatgga cgcactaagc
    20881 gtatggggga agagttagtt gagaagcatg tgtctaattt ctatattatc cgtactgcct
    20941 gggtatttgg aaattatggc aaaaacttcg tttttaccat gcaaaatctt gcgaaaactc
    21001 ataagacttt aacagttgta aatgaccagt acggtcgtcc gacttggact cgtaccttgg
    21061 ctgagttcat gacctaccta gctgaaaatc gtaaggaatt tggttattat catttgtcaa
    21121 atgatgcgac agaagacaca acatggtatg attttgcagt tgaaattttg aaagatacag
    21181 atgtcgaagt caagccagta gattccagtc aatttccagc caaagctaaa cgtccgctaa
    21241 actcaacgat gagcctggcc aaagccaaag ctactggatt tgttattcca acttggcaag
    21301 atgcattgca agaattttac aaacaagaag tgagataagt agtagaatga ttttctagtc
    21361 taataaaaga ggcagagaat gaactccaaa ggagcttaag atgtacgatt atcttgttgt
    21421 tggtgcagtc tttgcccatg aagcagtctt aaaaggaaaa aaagtaaaag ttattgaaaa
    21481 atgaaatcat atcgcgggta atatctatac tcgtgaagag gaaggaattc aagttcatca
    21541 atatggtgct catatcttcc atacttctga taaggagatc tgagattatg taaatcagtt
    21601 tgcagagttt aaccgttata ccaattctcc tgttgcaaac tataagggag agatttataa
    21661 cttacctttt aatatgaata ccttcaataa actctgggga gttgtgacgc cagcagaagc
    21721 acaagctaag attgatgaac aacgtgctat tttaaatggt aaaactcctg aaaatttgga
    21781 agaacaggcg atttctcttg taggtacaga catctacgaa aaattaatca aagactatac
    21841 agagaaacag tggggcaaac caactactga acttccatcc tttattattc gccgtttacc
    21901 agtacacctg acctatgata acaactattt taacgatacc tatcaaggga ttccaattgg
    21961 tggttataat gttatcatcg aaaatatgct gaaggatgta gaagtagaac ttggagtgaa
    22021 cttttttgcc aatcgtcaag aattagaggc ttctgctgaa aaggttgtct ttacagggat
    22081 gattgaccaa tcctttgatt ataaacatgg tgagttagaa tactgtagtc ttcgttttga
    22141 tcatgaagtt ctagatgagg aaaactatca aggaaacgca gttgtgaact atatggatgc
    22201 agaaacccca tatactcgca ttattgaaca caaacatttt gagtttggga gtcaagcaaa
    22261 gactatcatt actaatagaa cattctaaaa catgggaaaa aggtgatgag ccttattatc
    22321 cagttaataa tgatcgtaat aatcatttgt ataaatcata taaaaaactt gctgatgagc
    22381 aagggaatgt tatctttggt ggccgcttag gacactatcg ttattacgat atgcaccaag
    22441 taattggagc agctttgcag tgcgtgagaa atgagttaga ttcatactca atgaaaatca
    22501 aagagcaaac taggaagcta gccgtaggtt gctcaaaaca ctgttttgag gttgcagatg
    22561 gaagctgacg cggtttgaag agattttcga agagtataaa caagtaaaac tgactaccag
    22621 ttattattta gaaatagtat taaaaattcc ttgactatgt gatatagttg agggattttt
    22681 aaatgatatt catatttttt gcaaagatgt tgtttgaaaa ataattttca aaaattctga
    22741 aaattctgtt gacaactttc tgaaaagagt ctataatgga gagaaagttt taaaggagaa
    22801 aatgatgaaa agttcaaaac tatttgccct tgcgggcgtg acattattg
//
