LOCUS       CR931679               20454 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 34365 (serotype 20).
ACCESSION   CR931679
VERSION     CR931679.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20454)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 20454)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..20454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="34365"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC20_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC20_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI33709.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..461
                     /gene="aliB"
                     /locus_tag="SPC20_0002"
                     /pseudo
     CDS             293..461
                     /gene="aliB"
                     /locus_tag="SPC20_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(462..995,997..1323))
                     /gene="tnp"
                     /locus_tag="SPC20_0003"
                     /pseudo
     CDS             complement(join(462..995,997..1323))
                     /gene="tnp"
                     /locus_tag="SPC20_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(933..995,997..1305))
                     /gene="tnp"
                     /locus_tag="SPC20_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 7.3e-23"
                     /pseudo
     gene            1536..2981
                     /gene="wzg"
                     /locus_tag="SPC20_0004"
     CDS             1536..2981
                     /gene="wzg"
                     /locus_tag="SPC20_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33712.1"
                     /db_xref="GOA:Q4K0T8"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T8"
                     /translation="MSRRFKKSGSQKVKRSVNTVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLPFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVVVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFYFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1536..1652
                     /gene="wzg"
                     /locus_tag="SPC20_0004"
                     /note="Signal peptide predicted for SPC1052 by SignalP 2.0
                     HMM (Signal peptide probability 0.992) with cleavage site
                     probability 0.539 between residues 39 and 40"
     misc_feature    1740..2087
                     /gene="wzg"
                     /locus_tag="SPC20_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 9.8e-64"
     misc_feature    2265..2708
                     /gene="wzg"
                     /locus_tag="SPC20_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 1.5e-69"
     gene            2983..3714
                     /gene="wzh"
                     /locus_tag="SPC20_0005"
     CDS             2983..3714
                     /gene="wzh"
                     /locus_tag="SPC20_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33713.1"
                     /db_xref="GOA:Q4K0T7"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T7"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGVRMIVSTSHRR
                     KGMFETPEEKIATNFIKVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     misc_feature    2986..3594
                     /gene="wzh"
                     /locus_tag="SPC20_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 4.1e-38"
     gene            3723..4415
                     /gene="wzd"
                     /locus_tag="SPC20_0006"
     CDS             3723..4415
                     /gene="wzd"
                     /locus_tag="SPC20_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33714.1"
                     /db_xref="GOA:Q4K0T6"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T6"
                     /translation="MKEQNTLEIDVLQLFRTLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVFLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     misc_feature    3741..4157
                     /gene="wzd"
                     /locus_tag="SPC20_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 7.4e-54"
     misc_feature    4263..4340
                     /gene="wzd"
                     /locus_tag="SPC20_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4425..5108
                     /gene="wze"
                     /locus_tag="SPC20_0007"
     CDS             4425..5108
                     /gene="wze"
                     /locus_tag="SPC20_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33715.1"
                     /db_xref="GOA:Q4K0T5"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T5"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTEKLFLGVILNKFDVQHEKYGSY
                     GGYGNYGKK"
     gene            5130..6500
                     /gene="wchA"
                     /locus_tag="SPC20_0008"
     CDS             5130..6500
                     /gene="wchA"
                     /locus_tag="SPC20_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33716.1"
                     /db_xref="GOA:Q4K0T4"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T4"
                     /translation="MEGRGFYNITLAFLQSILVSLLAYILIAISETDIALNTVFVLFF
                     LHFVAFYISGYGKDFFKRGQYIELVETIKYIIFYSLLISFSSLFLKEKFVISRRGMLY
                     LLFLYGVLNYLLNFFLKSYWRKFTYNLKRSRKILLVTATSRVERVMDCLLLANDVQGK
                     LVAVSVLDKPEFTHEKLLVVPKEELISYATHEVVDEVFVNLPSEDYDIGAIISQFETM
                     GVDVTVNLNAFDKNLSRNKRIHEMAGLNVVTFSTNFYKPSHVITKRILDICGAIVGLF
                     ICGIASIFIVPQIRKDGGSAIFSQTRVGKNGRHFTFYKFRSMRVDAEAIKEQLMDQNT
                     MQGGMFKIDNDPRVTKIGKFIRKTSLDELPQFWNVLIGDMSLVGTRPPTVDEYEKYTP
                     EQKRRLSFKPGITGLWQISGRSEITNFDEVVKLDVAYIDDWTIWKDFEILLKTVKVVL
                     MRDGAK"
     misc_feature    5916..6497
                     /gene="wchA"
                     /locus_tag="SPC20_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 3.2e-150"
     gene            6508..7299
                     /gene="wciB"
                     /locus_tag="SPC20_0009"
     CDS             6508..7299
                     /gene="wciB"
                     /locus_tag="SPC20_0009"
                     /note="member of homology group 16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33717.1"
                     /db_xref="GOA:Q4K0T3"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T3"
                     /translation="MTNIKIIVATHKSFEMPQNKELYFPVHVGCEGKDDLGYQGDNTG
                     ENISQLNPYYCELTGLYWAWKNLDCDYLGLVHYRRYFTKKTQFYKENLKIDEVILNQE
                     EIELLLRKGDIIVPKKRKYYIETLCSHYAHTLDASHLDLARKVIEKQQPEYLDSFDKV
                     MKQRSGYMFNMFIMKKELANNYFEWLFPILDCMFDQINLSELTAFEARLFGRVSELLF
                     NVWLEKNLYSLVEVPFMYLEKVNLVEKGKSFLMAKFFGKKYGQSF"
     gene            7311..8378
                     /gene="wzy"
                     /locus_tag="SPC20_0010"
     CDS             7311..8378
                     /gene="wzy"
                     /locus_tag="SPC20_0010"
                     /note="member of homology group 238"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33718.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T2"
                     /translation="MIYIGTMLLSMLIITFIKYFRISKKWKEAVYFWGFIPLILIGAL
                     RAYVGIDYTTYSLDQIPAVLAGSQTVKFELLDKLVVYIGYYLANQQHYFYIFAIFHII
                     LMWFLYKYIVQQSSNVMLSVFFLLTTVFFTFSLSGIRQSIATAIVFYALKYIKQKKSL
                     HYIIYLGIACLFHSSAVIYILFLVLGKININRFVGFALPMIASLFSFSGSEFVSRIIL
                     HLNFYSEYVGSRYYTGAYDKQHQLFTIVMCLSVFLLYYIVPKKEWVNLKLYLNINFVL
                     LLVAIIMPILPTPSRTIYMFVLVHVILIPKLISVIKDYRSKVIITMFFVLGYFIFFSI
                     TVLQRNAYETLPYHTIFEYLW"
     gene            8379..9407
                     /gene="whaJ"
                     /locus_tag="SPC20_0011"
     CDS             8379..9407
                     /gene="whaJ"
                     /locus_tag="SPC20_0011"
                     /note="member of homology group 193"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33719.1"
                     /db_xref="GOA:Q4K0T1"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T1"
                     /translation="MIMKQILISIIIPLHNGEDTIIRAVKSVINSRLYGDLIEIIIVE
                     NGSTDQSFKISQKLATENSNIRVLKSDKGTSFARNVGIEKSKGKWLIFLDADDYLFES
                     DLDVIVENLITNNTDLCVYNYEKGLKKIELFSEEVELIDDLDSFIVQSLSEPTKYMTV
                     WGKAFNKNLIDEYGLKFNTNLRVSEDSDFYLRFLLLIHSLTLTSQTLYHYSIDSPSTM
                     RTFSSDKLEGYIVSLNESSKVLGNVDNTIQEAFELYKLAHFNLIMVREVFYFDNSKSF
                     REKIKEMIRLYKMPMFFEPIQNLSVSSVSNLSLVPLFFLKIHLYHLAALVYIIRVGQN
                     KFKEGRKS"
     misc_feature    8403..8900
                     /gene="whaJ"
                     /locus_tag="SPC20_0011"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1e-31"
     gene            9407..10522
                     /gene="wciL"
                     /locus_tag="SPC20_0012"
     CDS             9407..10522
                     /gene="wciL"
                     /locus_tag="SPC20_0012"
                     /note="member of homology group 30"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33720.1"
                     /db_xref="GOA:Q4K0T0"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K0T0"
                     /translation="MKRILVFGMNENPGGVESFIMNYFREFNREKLALDFLCNSNDKI
                     AYEDELISKGARVFHLTARSKNPIRYYWEMYRFFKEYASDYQAIWVNINSLANIDYLK
                     FARYFGIPVRIVHSHNSQNMDTKLREKLHNHNRDKIEKWATDFWACSHEAAKWFYNEE
                     TIGKVKIIPNAINMNASIFSSEARDKIRIDYTLDNKFVLGHVGRLHFQKNQEFMIRVL
                     AKLQEFRDDVCLVLVGQGEDLNKLKILAEELSIQDKVYFVGVQSNISEWLSTFDLFFF
                     PSNFEGLGIAALEAQVNGLPTLLSEEGVPKEVKINDNTFFYPLKESEESWANFLDEMI
                     HTTTRLNYEYIQENFEKSGYDIKIAAQNLEKQLLELV"
     misc_feature    9956..10459
                     /gene="wciL"
                     /locus_tag="SPC20_0012"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.5e-30"
     gene            10533..11522
                     /gene="wcwK"
                     /locus_tag="SPC20_0013"
     CDS             10533..11522
                     /gene="wcwK"
                     /locus_tag="SPC20_0013"
                     /note="member of homology group 64"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33721.1"
                     /db_xref="GOA:Q4K0S9"
                     /db_xref="UniProtKB/Swiss-Prot:Q4K0S9"
                     /translation="MVNNIDFVVTWVNGNDPVWREEKKKYEVLDGRPTLNDETRYRDM
                     DLFQYWFRAVEKHAPWVNNIYFITYGHLPEWLDANHPKLKIVKHEDYIPKEYLPTFSS
                     NVIELNLFRIKELSEQFVLFSDDVFINTFLKEEDLFKNNLPRLLSIYRPLIPTKEFDY
                     INFNHLLIMNRYFHDKKTLSQHKGKFFNVGYGKFNLYNLFSIFYSGIIGYHDAHVAMP
                     HLKSTFAEIWNKEGVLLDRVCKNKFRSTKDVNHWLMSYWNIETNSFMPQTLRVGEYVP
                     LAYSGKIESIIHKQKNKFLCINDDEHTENFINEVNFVRKIFEKKFPEKSKFEK"
     gene            11535..12539
                     /gene="wciD"
                     /locus_tag="SPC20_0014"
     CDS             11535..12539
                     /gene="wciD"
                     /locus_tag="SPC20_0014"
                     /note="member of homology group 60"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33722.1"
                     /db_xref="GOA:Q4K0S8"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S8"
                     /translation="MKKQKILSVVIPSYNAAPFLMETIPTLVSISSRNDIEVLIVNDG
                     SKDETLQVAQKLEKEYSGIVSIIDKENGGHGSTINAGIREAKGKYFKVVDADDWVDSE
                     NFEKLVQFLHKTDADEIISPYTDVFEDDGTKVENNYFKDCSLKPYQDYDYVNFLERIQ
                     ILPRMHSITIKTSILRDNNIKIDENMFYVDMEYIVFPTPFIKTITYTPDSVYQYRRGY
                     EGQSTSIQNYIKNRKMVNHVTFALLDFYNKHTLSNILEKLVKETIARCVTIMTNVCLS
                     MEDTKQGKKELLDFDQKLKSINSEFYYHKQGKKAKVLRYSNYFLFDLLSSYSKKSKKV
                     "
     misc_feature    11556..12095
                     /gene="wciD"
                     /locus_tag="SPC20_0014"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1.2e-32"
     gene            12559..13521
                     /gene="whaF"
                     /locus_tag="SPC20_0015"
     CDS             12559..13521
                     /gene="whaF"
                     /locus_tag="SPC20_0015"
                     /note="member of homology group 138"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33723.1"
                     /db_xref="GOA:Q4K0S7"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S7"
                     /translation="MIHKIINRLSLTIQQCSGDKPFTIKLVNAYVELLRNTKSRELRN
                     YVIKKHIKKTTNISQIKEVFLENSNTLIQKTEFPKFIWTMWWQGEENAPELVQSTLYY
                     IRKFAETNGYTTVVIDKNNIDKYLVVPEFVYAKLEKGSIGVANFSDLIRFMLMEQYGG
                     IWLDSTMYVHPDFPIEILEREFSSINHRDNSSQSMDDNITNKRWVSFCLSGEKGNIVS
                     RAMRAFLLDQIENNKVLPDYFIIDFGLDYLYDEFEEIREIIKSIPRYSSQEDIFWLRI
                     HSKDSFNKEEWYNETKKNQLFKSSYKEDETVKDSYFDYLVKRKL"
     misc_feature    12670..13503
                     /gene="whaF"
                     /locus_tag="SPC20_0015"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 8.4e-44"
     gene            13528..14943
                     /gene="wzx"
                     /locus_tag="SPC20_0016"
     CDS             13528..14943
                     /gene="wzx"
                     /locus_tag="SPC20_0016"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI33724.1"
                     /db_xref="GOA:Q4K0S6"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S6"
                     /translation="MKVIKNYAYNLSYQLLVIILPIITTPYVTRVFSSNDLGTYGYFS
                     SIVTYFILLASLGVANYGTKVISGNRKEIEKNFWGIYSLQMGATLLSLFLYLVLCLTL
                     PFMQNLVAYILGLSLVSKGLDISWLFQGLEDFRKITVRNITVKLVGVISIFLFVKSAN
                     DLYLYVFLLTIFELFGQLSMWLPARDFIGKFHVDIEYARQHLKPIILLFLPQVAISLY
                     VTLDRTMLGALASTKDVGIYDQALKLVNILLTFVTSLGSVMLPRVSHLLATGERKAVN
                     KMHEMSFLIYNLLIFPIMAGILIVNDDFVQLFLGQDFQDARYAIAIMVLRMFFIGWTN
                     IMGTQMLIPHNQNKEFMISTTAPAIISVGLNLLFLPKLGYIGAAIVSVLTEALVWVIQ
                     LFYTRRYLKEVPIIGSMSKIILASAIMYGLLLSSKTVIHFSSTLNVLAFAALGGIIYI
                     FAILSLKVVDVKELKQIIRKN"
     misc_feature    13534..14328
                     /gene="wzx"
                     /locus_tag="SPC20_0016"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.9e-67"
     gene            14945..15943
                     /gene="wciG"
                     /locus_tag="SPC20_0017"
     CDS             14945..15943
                     /gene="wciG"
                     /locus_tag="SPC20_0017"
                     /note="member of homology group 21"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33725.1"
                     /db_xref="GOA:Q4K0S5"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S5"
                     /translation="MRKNRNINLDLLKVLACVGVVLLHTTMGGFKETGSWNLLAYLYY
                     LGTYSIPLFFMVNGYLLLGKREITYLYILQKVKWILITVSSWSFIVWLFKRDFTTNPI
                     KKIVGSLIQRGYFFQFWFFGALILIYLCLPILRQFLNSKRSYLYSLSLLMTIGLIFEL
                     SNILLQMPIQTYVIQTFRLWTWFFYYLLGGYIAQFTIEEIESRFKNWMKIVSILLLLI
                     SPIILFFIAKTIYHNLFAEYFYDTLFVKVSTLGIFLTILMLTLNESRRESIVSLSNQT
                     MGVFIIHTYIMKVWEKVLGFNFVGAYLLFALFTLSVSFIIVGMLMKIPYFNRIVKL"
     gene            15957..17066
                     /gene="glf"
                     /locus_tag="SPC20_0018"
     CDS             15957..17066
                     /gene="glf"
                     /locus_tag="SPC20_0018"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI33726.1"
                     /db_xref="GOA:Q4K0S4"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S4"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRDHIGGNIYCEN
                     LEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYVNSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTADMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELEVDFFAHRE
                     GLEASAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDEKNNAMFAKYQEEASKNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFGYDKK"
     misc_feature    16392..16994
                     /gene="glf"
                     /locus_tag="SPC20_0018"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 1.1e-136"
     gene            17053..18105
                     /gene="wcjE"
                     /locus_tag="SPC20_0019"
     CDS             17053..18105
                     /gene="wcjE"
                     /locus_tag="SPC20_0019"
                     /note="member of homology group 18"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33727.1"
                     /db_xref="GOA:Q4K0S3"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S3"
                     /translation="MTKSRINWIDFGKGFSIFLVLAGHVLLGLYQSEKFPTANNILSL
                     LIAQVYIFHIPVFFALSGYFFKPVSDLKEFWQYAKKKTIVFGLPYIFYSIIHFGLQKV
                     AGASVRVPTTISDLLNIYKDPLGVSWYLYILWSILIIYGLLSILVKNRRMLFLISVFA
                     YCLTLFVQTDIYIIQRTLVWGLCFFLGSVLNEIHFDKINLKKFLFLFVLFDFIYMFAW
                     FLFYEVGSKKDYVSYSNSGLWGIAFVVCVLVAFAIFPKMEKNFPKTFLYFTKYGKDSL
                     GIYILHAPICSMIRILMLKVGINSVFLHVVVGIVLGWYLSILATYILKKIPFLNIVLL
                     PQKYIKLKGSLSTVVG"
     gene            18121..18652
                     /gene="tnp"
                     /locus_tag="SPC20_0020"
                     /pseudo
     CDS             join(18121..18462,18446..18652)
                     /gene="tnp"
                     /locus_tag="SPC20_0020"
                     /note="member of homology group 31"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase"
     misc_feature    18464..18649
                     /gene="tnp"
                     /locus_tag="SPC20_0020"
                     /note="HMMPfam hit to PF05717, IS66 Orf2 like protein,
                     score 5.3e-15"
                     /pseudo
     gene            complement(18874..19059)
                     /gene="tnp"
                     /locus_tag="SPC20_0021"
                     /pseudo
     CDS             complement(18874..19059)
                     /gene="tnp"
                     /locus_tag="SPC20_0021"
                     /note="member of homology group 0047 7"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            19162..20095
                     /gene="tnp"
                     /locus_tag="SPC20_0022"
                     /pseudo
     CDS             join(19162..19884,19886..20095)
                     /gene="tnp"
                     /locus_tag="SPC20_0022"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     gene            20302..>20454
                     /gene="aliA"
                     /locus_tag="SPC20_0023"
     CDS             20302..>20454
                     /gene="aliA"
                     /locus_tag="SPC20_0023"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33731.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYL"
     misc_feature    20302..20388
                     /gene="aliA"
                     /locus_tag="SPC20_0023"
                     /note="Signal peptide predicted for SPC1073 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
BASE COUNT     6676 a   3002 c   3914 g   6862 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attatcgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga aaatgaacat
      301 aaagaagcgt gtccttagtg caggtctgac ttttgcatct gctttgcttt tagctgcttg
      361 cgaccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaattac ctgttagact attacgctga taatatagtc aattgaaaca agagcaggac
      481 aaaagagcct cgtaaaaggt attgcaactt ggtaatacct tttacgaggc tttttgatat
      541 gagcccatgt tttctcaata ggattgtact caggtgagta gggaggaaga aggtaaaagt
      601 ttatgcctaa actcttcaca caagagttct agcttcccca ttctatggaa tcttgcatta
      661 tccataataa taaccgatgg tgtggttaat gttggtaaga gaaacttctg aaaccaagct
      721 tcaaaaaagt cgctcgtcat cgtctcttcg taagtcattg gagcgattaa ctcaccattt
      781 gttagacctg caaccaaaga aatcctctga tatcttcttc cagatacttt gcctcttatt
      841 aactgacctt ttaatgagcg accatattct cgataaaaat aagtatcgaa tcctgtttcg
      901 tcaatctaaa caggtgctag gtgctttaat ctattaaaat tcttaagaaa taaggctact
      961 ttttctggct cttgttcata gtaggtgtgg ttcttttttt cgagtgtagc ccatagcttt
     1021 gagcgcatag tggatggtag ttggatgaca gccaaattca gaagctattt cagtcaaata
     1081 agcgtctgga ttgtcagtaa gatagttttt aagtctatct ctatcaactt ttcttggttt
     1141 tattcctttt acttggtggt ttagctctcc tgttttctct tttagcttta accagccata
     1201 aatggtatta cgtgagattt ggaaaacgtg tgatgcttct gttatactac ctgttcgctc
     1261 acaataagag agaacttttt tacgaaaatc tattgaatat gccataaaaa gattatacca
     1321 cattgtgtac tatattagat tgaaactaga atagtacaca tctgcttcta aaacattgtt
     1381 agaaatcgat ttgactgtcc ttatttcatt ttattatatt tttggttcgc gggaagtcta
     1441 ctaagatact taaagatgca gatagtaaaa aaaatgtaga cattaccgta aaaaagtgat
     1501 ataatcgtat gatgttcaag gtataggtgt taaccatgag tagacgtttt aaaaaatcag
     1561 gttcacagaa agtgaagcga agtgttaata ccgttttgct gactatttat ttattgttag
     1621 tttgtttttt attgttctta atctttaagt acaatatcct tgcttttaga tatcttaacc
     1681 tagtggtaac tgcgttagtc ctactagttg ccttggtagg gctactcttg attatctata
     1741 aaaaagctga aaagtttact atttttctgt tgccgttctc tatccttgtc agctctgtgt
     1801 cgctctttgc agtacagcag tttgttggac tgaccaatcg tttaaatgcg acttctaatt
     1861 actcagaata ttcaatcagt gtcgttgttt tagcagatag tgatatcgaa aatgttacgc
     1921 aactgacgag tgtgacagca ccgactggga ctgataatga aaatattcaa aaactactag
     1981 ctgatattaa gtcaagtcag aataccgatt tgacggtcaa ccagagttcg tcttacttgg
     2041 cagcttacaa gagtttgatt gcaggggaga ctaaggccat tgtcctaaat agtgtctttg
     2101 aaaacatcat cgagttagag tatccagact acgcatcgaa gataaaaaag atttatacca
     2161 agggattcac taaaaaagta gaagctccta agacgtctaa gaatcagtct ttcaatatct
     2221 atgttagtgg aattgacacc tatggtccta ttagttcggt gtcgcgatca gatgtcaata
     2281 tcctgatgac tgtcaatcga gataccaaga aaatcctctt gaccacaacg ccacgtgatg
     2341 cctatgtacc aatcgcagat ggtggaaata atcaaaaaga taaattaacc catgcaggca
     2401 tttatggagt tgattcgtcc attcacacct tagaaaatct ctatggagtg gatatcaatt
     2461 actatgtgcg attgaacttc acttctttct tgaaaatgat tgacttattg ggaggggtag
     2521 atgttcataa tgatcaagag ttttcagctc tacatgggaa gttctatttc ccagtaggga
     2581 atgtccatct agactctgag caggctctag gttttgtacg tgaacgctac tcactagccg
     2641 atggagaccg tgaccgtggt cgcaaccaac aaaaggtgat tgtggctatc cttcaaaaat
     2701 taacgtcaac cgaagcactg aaaaattata gtacgatcat taatagcttg caagattcta
     2761 tccaaacaaa tatgccactt gagactatga taaatttggt caatgctcag ttagaaagtg
     2821 gagggaatta taaagtaaat tctcaagatt taaaaggtac aggtcggacg gatcttcctt
     2881 cttatgcaat gccagacagt aacctctatg tgatggaaat agatgatagt agtttagctg
     2941 tagttaaagc agctatacag gatgtgatgg agggtagatg aaatgataga catccattcg
     3001 catatcgttt ttgatgtaga tgacggtccc aagtcaatag aggaaagcaa ggcactttta
     3061 agagaagctt ataatcaagg agttcgaatg attgtgtcta cttcgcatcg tcgaaaaggg
     3121 atgtttgaaa ctccagaaga aaaaattgca acaaatttta ttaaggttcg tgaaattgca
     3181 aaagaagtag cagatgattt agtcatagct tatggcgcag agatatacta tactctggat
     3241 gctctagaaa agctagaaaa aaaagaaatt cctaccctta atgatagtcg ttatgctttg
     3301 attgagttta gcatgcatac ttcctatcgt gagattcatg cgggattgag caatattttg
     3361 atgttgggaa tcacgccagt aattgctcat attgaacgtt atgatgcctt agagaataac
     3421 gaaaaacgtg ttcgtgaact gattgatatg gggtgctata ctcagataaa tagttatcat
     3481 gttttaaaac ctaagttctt tggtgaaaaa tataaattca tgaaaaagag agctcggtat
     3541 tttttggaac gtgatttagt tcatgtagtt gcaagtgaca tgcacaattt agacagtaga
     3601 cctccatata tgcaacaggc atatgatatc attgctaaga aatatggagc gaaaaaagcg
     3661 aaagaatttt ttgtagataa tcccagaaaa attataatgg atcaattaat ttaggagaaa
     3721 atatgaagga acaaaacact ttggaaatcg atgtattgca actattcaga actttatgga
     3781 aaagaaagtt ggtcatttta ttagtggcaa ttataacttc ttcagttgct tttgcctaca
     3841 gtacttttgt tatcaaacct gagtttacta gtacgactcg gatttatgta gttaaccgta
     3901 atcaggaaga gaagtctggt ttaaccaatc aagacttgca ggcaggatca tacttggtca
     3961 aagactatcg tgaaattatc ctatcgcagg atgttttgga ggaagttatt tctgatttga
     4021 aactagattt gacgccaaaa ggtttggcta ataaaattaa agtaacagta ccagttgata
     4081 cccgtattgt ctctgtttca gttaatgatc gagttcctga agaggcaagc cgtatcgcta
     4141 actctttgag agaagtagct gctcaaaaaa ttatcagtat tactcgtgtt tctgatgtga
     4201 caacactgga ggaagcaaga ccggcgatat caccatcttc gccaaatatt aaacgcaata
     4261 cactaattgg ttttttggca ggggggattg gaactagtgt tatagttttt cttcttgaac
     4321 ttttggacac tcatgtgaaa cgtccggaag atatcgaaga tacactgcag atgacacttt
     4381 tgggagttgt accaaacttg agtaagttga aataggagag aggaatgccg acattagaaa
     4441 tagcacaaaa aaaactggag ttcattaaga aggcagaaga atattacaat gccttgtgta
     4501 caaatataca gttgagcgga gataaactaa aagtaatttc cgttacttct gttaaccctg
     4561 gggaaggaaa aacaactact tccgtaaata tagcaaggtc gtttgcgcgt gcaggctata
     4621 aaactctttt gatcgatggc gatactcgaa attcagttat atcaggagtt tttaaatcgc
     4681 gtgaaaaaat tacagggcta acagaatttt tatctgggac agctgattta tctcacggtt
     4741 tatgtgatac aaatattgaa aatttatttg taattcaatc gggatctgta tcaccaaacc
     4801 ctacagcctt gttacaaagt aaaaatttta atgatatgat tgaaacattg cgtaaatatt
     4861 ttgattatat cattgttgat acagcaccta ttggaattgt tattgatgcg gcaattatca
     4921 ctcaaaagtg tgatgcgtcc atcttggtaa cagcaacagg tgaggtgaat aaacgtgatg
     4981 tccaaaaagc gaaacaacaa ttagaacaaa cagagaaact gtttttaggt gtcattctca
     5041 ataaatttga tgttcaacat gaaaaatatg gttcttacgg tggctatggt aattacggaa
     5101 aaaaatagaa tgaagttagg gagtccagta tggaaggaag gggtttctac aatataactc
     5161 tggcattctt acagagtata cttgttagtc tattagctta tatactgatt gcaatttcag
     5221 aaaccgacat tgctttaaat acagtattcg tcctgttttt tcttcacttt gtagcctttt
     5281 atattagtgg ttatggtaaa gattttttca aaagaggtca gtatattgag ttggtagaaa
     5341 cgataaaata cataatattt tattccttgt tgatcagctt ttcaagtttg ttcttaaaag
     5401 aaaaatttgt tatttctaga cgaggaatgc tctacttgct tttcctatat ggtgttttga
     5461 attatctact caatttcttt ttgaaaagtt attggagaaa attcacctat aatttaaagc
     5521 gcagtcgcaa gattttattg gttacggcaa catcacgcgt cgaaagagta atggattgcc
     5581 tgttacttgc gaacgatgtt caagggaaat tggttgctgt tagtgtttta gataagccag
     5641 aatttactca tgaaaagctc cttgttgtac caaaagaaga gttgatttcc tacgctaccc
     5701 atgaagtagt agatgaagtt tttgtcaatc ttccaagtga ggactatgat attggagcca
     5761 ttatttctca gtttgaaaca atgggggttg atgtaacagt caatctcaat gcttttgata
     5821 aaaacttaag ccgaaataaa cgaatccatg aaatggcagg attgaatgta gtgaccttct
     5881 ctacgaattt ttacaagcct agtcatgtca ttactaagag gattcttgat atttgtggag
     5941 ctatcgttgg tctttttatc tgtggaattg ctagtatatt catagttcct cagattcgaa
     6001 aagatggtgg gtctgcaatc ttttcacaaa ctcgtgtagg aaaaaatggt cgtcacttta
     6061 ccttttataa attccgctcg atgcgagtcg atgcagaagc gatcaaggaa cagttgatgg
     6121 atcaaaatac gatgcaaggt ggtatgttta agatcgataa cgatcctcga gtgacaaaga
     6181 ttggaaaatt tatccgaaaa actagcttgg atgaattgcc acaattttgg aatgttttaa
     6241 ttggagacat gagtctagta ggtacgcgcc caccaactgt agatgagtac gaaaaataca
     6301 cacctgaaca aaaacgtcgc ctaagcttta aacctggtat tacaggtttg tggcaaatta
     6361 gtggtcgaag tgaaattaca aacttcgatg aggttgttaa gttggatgtg gcttatatcg
     6421 atgattggac catttggaaa gattttgaaa tattgttaaa aactgtaaaa gttgtgttga
     6481 tgagagatgg agcgaagtag gaggggtatg acaaatatta aaattatagt tgcaactcat
     6541 aagagttttg agatgccgca aaataaagaa ttgtatttcc cagtccatgt ggggtgtgaa
     6601 ggaaaagatg atttgggata tcaaggagat aatactgggg aaaacatttc ccagttaaac
     6661 ccttattact gtgaattaac aggtttatat tgggcatgga agaatctaga ttgcgattat
     6721 cttggactag ttcattaccg ccgatatttc acgaagaaaa ctcaatttta taaagaaaat
     6781 ctaaaaattg atgaagtaat tttaaatcag gaagaaattg aattgctttt gagaaaagga
     6841 gatataatag ttcctaaaaa aaggaaatat tatattgaaa ctctatgttc tcattatgca
     6901 cacacgctag atgctagcca tctagatttg gctagaaaag tcattgagaa gcaacaacct
     6961 gaataccttg attcatttga taaagttatg aaacaacgta gtggctatat gtttaatatg
     7021 tttataatga aaaaggaatt agcaaataat tattttgaat ggctgtttcc gattttagat
     7081 tgtatgtttg atcagattaa tctttcagag ttaactgcat ttgaggcacg tctttttggt
     7141 cgtgtaagtg aactattatt caacgtatgg ctagagaaga atttgtattc tctagtagaa
     7201 gttccattta tgtatttgga aaaggttaat ctagtagaaa aagggaaatc gtttttaatg
     7261 gctaaatttt ttggtaagaa gtatggacag agtttttagg gaggaactaa ttgatttaca
     7321 ttggtacgat gcttctctca atgttgataa ttacttttat caagtatttt agaatatcaa
     7381 aaaaatggaa agaggcagtt tatttttggg gttttattcc tcttatcttg ataggagcac
     7441 ttagagctta tgtaggaata gattatacca catatagttt ggatcagata ccggctgtat
     7501 tagctggtag tcagacagtc aaatttgaat tgttagataa attagtagtg tacataggtt
     7561 actatctagc taatcagcag cattatttct atatttttgc aatatttcac attatcctga
     7621 tgtggtttct gtataaatat attgttcaac agtcgtctaa tgtaatgttg agtgtgtttt
     7681 ttcttctaac cactgttttt tttacttttt ctttatcagg aatacgccaa tcaatagcta
     7741 cagcgattgt tttttatgcg ttgaagtata ttaaacaaaa aaaaagttta cattatataa
     7801 tttatttagg gattgcttgt ttatttcatt ctagtgcagt aatctatata ctttttttag
     7861 ttttagggaa aattaatatt aataggttcg ttggctttgc attaccgatg attgcatcat
     7921 tattttcttt ttctgggtct gaatttgtat ctcgaataat actacattta aatttttatt
     7981 cagaatacgt tggttctcgt tattatacag gagcatatga taaacaacac caactattca
     8041 caatcgttat gtgtttatcg gtatttctat tatattatat tgttccgaaa aaagagtggg
     8101 ttaatttaaa attatatctg aatattaatt ttgtgctatt actagttgca ataatcatgc
     8161 caatacttcc tactccatca agaactattt atatgtttgt tcttgtacat gttattctaa
     8221 ttcctaagtt gatttcagtt attaaagatt ataggtctaa ggtaatcata acaatgttct
     8281 ttgttttagg ttattttata ttcttttcta taacggttct acagaggaat gcatatgaaa
     8341 cactaccgta ccacacaatc tttgagtatt tatggtaatt gattatgaaa caaatattaa
     8401 tttctattat tattccatta cataatggag aagatacgat tattagagca gtaaaaagtg
     8461 ttataaatag cagattatat ggagatttga ttgaaattat tattgttgaa aatggttcaa
     8521 cagatcaatc atttaaaatt tctcaaaaat tagcgaccga aaactcaaat atacgagtct
     8581 tgaaatcaga taaaggaacc agttttgcca gaaacgtagg aatcgaaaaa tctaaaggaa
     8641 agtggcttat ttttttagat gcagatgatt atttatttga atcggattta gacgttattg
     8701 ttgaaaattt aataaccaat aatacagatt tatgcgttta taactacgaa aaagggctta
     8761 agaaaataga acttttttca gaagaggtag agttgataga tgaccttgat tcttttatag
     8821 ttcaatctct ttctgaaccc actaaatata tgacagtatg gggaaaagcg tttaataaaa
     8881 atttgattga tgagtacggt ttgaagttta atacgaattt gagagtttca gaagatagtg
     8941 atttttatct cagatttctt ttgctgattc acagtttaac tttaacttct caaacgctat
     9001 accattattc aattgattca ccttcaacga tgaggacatt ttcttcagat aaattagaag
     9061 gttatattgt ttccttgaat gaaagctcaa aagtattagg aaatgttgat aatactattc
     9121 aagaagcctt tgagttatat aagttggcgc attttaattt aataatggtt agagaagtgt
     9181 tctattttga taattcaaaa agtttcagag aaaagataaa ggaaatgatt agactttata
     9241 agatgcctat gttttttgag cctatacaaa atctatctgt atctagtgtt agcaatttat
     9301 cgctagtacc tctatttttt ttgaaaatac atttgtatca tttagcggca ttggtttaca
     9361 ttattcgagt agggcaaaac aaattcaaag aaggaagaaa aagttgatga aaagaattct
     9421 agtattcgga atgaatgaaa accctggtgg agttgaatcc tttataatga attattttcg
     9481 tgaatttaat cgcgaaaaat tagccttaga ttttttgtgt aattcaaatg ataaaatagc
     9541 ttatgaggat gaacttattt ctaaaggagc aagagttttt cacctgacag cgagaagtaa
     9601 aaatccgata cgttattatt gggaaatgta tagattcttc aaagaatatg catctgatta
     9661 tcaggcaatt tgggttaata ttaatagctt agcaaatatt gactatttaa aatttgcaag
     9721 atattttggt attccggttc gaattgtaca cagccataat agtcaaaata tggataccaa
     9781 acttcgtgaa aaattacata atcataatag agacaaaatt gaaaagtggg caaccgattt
     9841 ctgggcttgt tcgcacgaag ctgcaaaatg gttttataac gaagaaacta ttggaaaagt
     9901 taagattata ccaaatgcta ttaatatgaa tgcttctatt ttttcttctg aggcacgaga
     9961 taaaattcga attgattata cattagacaa taaatttgtg ctaggtcatg taggacgttt
    10021 gcattttcag aagaatcaag aatttatgat aagagtttta gctaaattac aggaatttag
    10081 agacgatgtc tgcttagttt tagttggtca aggtgaagat cttaacaaat taaagatact
    10141 ggctgaggag ctatctattc aggataaggt ctactttgtg ggagttcagt cgaatatatc
    10201 agaatggttg agtacttttg acttattctt ttttccgtct aattttgaag gtttaggaat
    10261 agctgcatta gaggctcaag taaatggtct accgacacta ctctcagaag aaggtgtacc
    10321 aaaggaagta aaaatcaatg ataatacttt tttttatcca ttgaaggaaa gtgaagaaag
    10381 ctgggcaaac ttccttgatg aaatgattca tacaacaact cgtttaaatt atgaatatat
    10441 acaagaaaat tttgagaaat ctggctacga tattaagata gctgctcaga atcttgaaaa
    10501 acaattgcta gaattagttt agggaagata acatggttaa taatattgat tttgtagtta
    10561 catgggttaa tggaaatgat ccagtgtggc gtgaggaaaa aaagaaatac gaagttctag
    10621 atggtaggcc gactttaaat gatgaaacaa gatatagaga tatggatttg tttcaatatt
    10681 ggtttcgagc ggtagaaaaa catgcgccct gggttaataa tatttatttc attacatatg
    10741 ggcatttacc tgaatggctg gatgcaaatc accctaaatt gaagatagta aaacatgaag
    10801 attatattcc aaaagaatac ttaccgactt ttagttcaaa tgtaattgaa ctaaatcttt
    10861 ttaggattaa ggaattgagt gagcagttcg ttctgtttag tgatgatgtt tttattaaca
    10921 catttttaaa agaagaagat ttgtttaaaa ataacttacc tcgattgttg agtatatata
    10981 gaccattaat tccaactaaa gaatttgatt atattaattt caatcattta ttaataatga
    11041 atagatactt tcatgataaa aaaacattat cacaacataa gggtaaattt tttaatgtag
    11101 gttatggaaa gtttaatctg tataatctat ttagcatttt ttattcaggg attattggtt
    11161 atcatgatgc tcatgtcgct atgcctcatt tgaaaagtac ttttgcagag atttggaata
    11221 aggaaggggt acttctagat cgagtttgta aaaacaaatt tcgttcaact aaagatgtta
    11281 accattggtt gatgagctat tggaatattg aaacaaattc atttatgcca cagactcttc
    11341 gtgtgggtga atatgtgcct ctggcttatt caggtaaaat tgaatctatt attcacaaac
    11401 aaaagaataa gtttttgtgt ataaacgacg atgaacatac cgaaaacttc attaacgaag
    11461 ttaactttgt tcgtaaaata tttgagaaaa aatttcctga aaagtctaaa tttgaaaagt
    11521 aaaggggaac taaattgaaa aaacaaaaaa tacttagcgt ggtaattcca tcctacaatg
    11581 cggctccatt tttgatggaa actattccga ctctagtttc tattagcagc agaaatgata
    11641 ttgaggtttt gattgtaaat gatgggtcta aagatgagac acttcaagtg gctcagaaac
    11701 tggaaaaaga gtattctggc atagttagta taattgataa agaaaatggc ggtcatggat
    11761 ctacaattaa tgctgggata agggaagcta aagggaagta ctttaaagtt gttgatgctg
    11821 atgattgggt agatagtgaa aactttgaaa agcttgtaca atttcttcat aaaacagatg
    11881 ccgatgaaat tatctctcca tatacagacg tttttgaaga tgatggtaca aaggtagaaa
    11941 ataactattt taaagattgt tcattaaaac cataccagga ttatgattat gtgaattttt
    12001 tagaacggat tcaaatttta cctagaatgc attctataac aataaaaacc tctattttaa
    12061 gagataataa cataaaaatt gatgagaata tgttctacgt tgacatggag tatattgttt
    12121 ttccaactcc atttatcaaa acaataactt atacgcctga ctctgtttat cagtatcgta
    12181 gaggttacga gggacagagt acgagtattc agaactatat aaaaaataga aaaatggtaa
    12241 atcatgtcac attcgctttg cttgactttt ataataaaca cactttatct aatattctgg
    12301 aaaaactagt taaagagaca attgctagat gtgttactat tatgacaaat gtttgtctat
    12361 caatggaaga tactaaacaa ggtaaaaagg aacttcttga ttttgatcag aaattaaaat
    12421 caataaattc tgagttctat tatcataaac aagggaaaaa agctaaagtt ctaagatatt
    12481 caaattactt cttgtttgac ttgttgtcta gctactctaa gaagtctaaa aaagtatagt
    12541 tgttgtagga gtatatatat gatacataaa attattaatc gattatcact tacgattcaa
    12601 caatgtagtg gcgataaacc atttactatc aaattagtta atgcatatgt agaactatta
    12661 agaaatacaa aatctagaga attaagaaat tatgtaataa agaaacacat taaaaaaacc
    12721 acgaatattt ctcaaattaa ggaagttttt ctagagaata gtaatacttt aatacaaaaa
    12781 actgaatttc ctaaatttat ctggactatg tggtggcaag gagaagagaa tgcacctgag
    12841 ttagtccaaa gtacactcta ttatattaga aaatttgctg aaactaatgg ttatacgaca
    12901 gtagttattg ataaaaataa tatagataag tatctagtag ttcctgaatt cgtatatgca
    12961 aagttggaga agggtagtat aggtgttgca aatttttcag atttaatccg atttatgcta
    13021 atggaacaat atggaggaat ttggttagat tcaacgatgt atgtccatcc agatttccct
    13081 attgaaatat tagaaagaga attttcttcg ataaatcata gggataattc cagccaatca
    13141 atggatgaca atataacaaa taaacgctgg gtttcatttt gtttgagtgg agagaaaggg
    13201 aacattgttt ctcgagcaat gcgagctttt ttattagatc aaattgaaaa taataaagta
    13261 ttacctgatt attttataat tgactttggt ttagattatc tatatgatga atttgaagag
    13321 ataagggaaa taataaaaag tatccctaga tattctagtc aagaagacat cttttggttg
    13381 agaatacata gtaaagatag ttttaacaaa gaagaatggt ataatgaaac gaaaaaaaat
    13441 caacttttca aaagtagcta taaagaagat gaaacagtga aagatagtta tttcgactat
    13501 cttgttaaaa gaaagttata aagtaaaatg aaagtaataa aaaactatgc ttacaatctt
    13561 tcatatcaat tattggtaat tatactccct attattacaa caccttatgt aacacgggtt
    13621 tttagttcta atgatttagg gacatacgga tactttagtt cgatagttac ttactttatt
    13681 ttgctggcta gtcttggcgt tgctaactat ggtactaagg taatctctgg aaatcgcaag
    13741 gagattgaaa aaaacttttg ggggatttac tcattgcaaa tgggtgcaac gcttctttct
    13801 ctattcttgt accttgttct ttgtttgacc cttcctttta tgcaaaatct agtagcctac
    13861 attcttggat tgagtttggt ttctaaaggt ttagatattt cctggctctt tcaaggttta
    13921 gaggattttc gaaagattac tgttcgaaat atcacagtca aactcgttgg tgtcatctcc
    13981 atctttctct ttgtcaaatc tgcaaacgat ctttatctct atgtcttttt gttaaccata
    14041 tttgaactct ttggacaact cagtatgtgg ttgccggctc gagactttat cggcaagttt
    14101 catgttgata tagaatacgc cagacagcat ttgaagccaa ttattttatt gttcctacca
    14161 caagtcgcga tttctttgta tgttacctta gatcgtacca tgcttggagc gcttgcttct
    14221 acaaaagacg ttggcatcta cgatcaagcc ctaaaattgg taaatattct tctaaccttt
    14281 gtaacttcat tgggaagtgt tatgctgcca cgagtatctc atctgcttgc gacaggtgaa
    14341 cgtaaggcag taaacaagat gcatgagatg tcttttttga tttataattt gcttattttt
    14401 ccgattatgg cggggattct gatcgtgaat gatgatttcg ttcagttatt tctaggacaa
    14461 gattttcaag atgcacgcta tgcaattgcg attatggttc tcaggatgtt ctttattggt
    14521 tggactaata taatgggaac tcagatgttg atcccccata accaaaataa agaatttatg
    14581 atttcaacaa cagctccagc cattattagc gttggattga atctattatt cctacccaag
    14641 ttaggttata taggagcagc cattgtctct gttttgacag aggcgctagt ttgggtaatt
    14701 caattattct atactcgcag atatttaaaa gaagttccta taatcggatc aatgtcaaaa
    14761 attatactag catctgccat tatgtatggc cttttactaa gttcaaaaac agttatacat
    14821 ttttcatcga ccttaaatgt tctagcattt gcagcgcttg gtggaatcat ttatattttt
    14881 gcaattctat ctctgaaagt ggtagatgtg aaagaattaa aacaaattat taggaaaaac
    14941 tagaatgaga aaaaatcgaa atattaacct agatttacta aaagtgcttg catgtgttgg
    15001 agttgtttta cttcatacaa caatgggcgg atttaaagag acaggctcat ggaatctttt
    15061 ggcatattta tattatttag gtacttactc tattcccctg ttttttatgg tcaatggtta
    15121 tttattgtta ggcaagaggg agataactta tctttacata ctccagaaag taaaatggat
    15181 tttaataaca gtgtcatcat ggtcgtttat cgtatggctt tttaagcgtg attttacaac
    15241 taatcctatt aaaaaaattg taggttcttt gatacaaaga ggttatttct ttcagttttg
    15301 gtttttcggt gcactaatac ttatctattt atgtttgcca attttgagac aatttctaaa
    15361 ttcaaaaaga agctatttat acagtttatc tttattgatg actattggtt tgatttttga
    15421 gttatcaaat atcctacttc aaatgccaat acaaacatat gtaatacaaa cttttagatt
    15481 atggacgtgg tttttttact atcttttagg tggttatata gcgcaattca ctatagaaga
    15541 aatcgaatca aggtttaaga attggatgaa aatagttagc atacttttgt tattgatttc
    15601 accaataata ttatttttca tagcgaagac tatataccat aatctatttg ctgaatactt
    15661 ttatgatact ttatttgtaa aagtcagtac tttaggaatt tttctaacta tcctcatgct
    15721 tactttgaat gaaagccgaa gagaatcgat tgtttccctt tctaatcaaa caatgggggt
    15781 tttcataata catacttata ttatgaaagt gtgggaaaaa gtgcttggtt ttaattttgt
    15841 aggagcatat ttactttttg ctctatttac tttaagtgtt agttttatta ttgttgggat
    15901 gttaatgaag attccttact tcaatcgaat cgtcaaatta taaaaaggag aacaagatgt
    15961 acgattatct tattgtcggt gctggtttgt caggagcaat ttttgcttat gaggcgacta
    16021 agcgtggaaa aaaagtaaaa gtgattgata aacgtgacca cattggtggg aatatctact
    16081 gtgagaatct agaaggagtt aatgttcata aatatggtgc ccatatcttt catacttcta
    16141 ataagaaagt ttgggattat gttaatcaat ttgctgaatt taacaactac gtcaactcgc
    16201 ctgtagctaa ttacaagggt agcctctata atctaccttt caatatgaat accttctatg
    16261 ctatgtgggg gacaaaaact cctcaagaag tcaaagataa gattgctgag cagacagctg
    16321 atatgaagga tgttgagccg aaaaatctgg aagaacaagc tatcaagctg attggtccag
    16381 atatctacga aaaattgatc aagggttata ctgaaaagca gtgggggcgc tcagcaacag
    16441 aacttcctcc atttatcatt aaacgacttc cagttcgtct aacatttgat aataactatt
    16501 ttaatgaccg ttaccaagga attcctattg gtggttataa tgtgattatt gaaaatatgc
    16561 ttaaagacgt agaagttgaa cttgaagtag atttctttgc tcaccgtgaa gggttggaag
    16621 catctgctga aaaagttgtc ttcacaggaa tgatcgacca atattttgac tacaaacacg
    16681 gagagttaga ataccgtagc cttcgttttg agcatgagat tttagacgag gaaaattatc
    16741 aaggaaatgc tgtagtgaac tatacggagc gtgagattcc ttatactcgt attatcgaac
    16801 acaagcattt tgaatatgga acgcaggcaa agacagttat cacgcgtgaa tatccagctg
    16861 actggaagcg tggggacgag ccttactatc cgatcaacga tgagaaaaat aatgctatgt
    16921 ttgctaagta ccaagaggaa gcttcaaaga atgataaggt tattttctgt ggacgtttag
    16981 cagattataa atattatgat atgcatgtgg tgattgaacg ggcgcttgag gttgtggaga
    17041 aagagtttgg atatgacaaa aagtagaatc aattggatag attttggaaa aggcttttcc
    17101 atatttttag tcttagcagg gcatgtgttg cttggactgt atcaatcgga aaaatttccc
    17161 acagcaaata acatactatc gttgttgata gcacaagtct acatatttca tataccagta
    17221 ttttttgcct tatcaggata ctttttcaaa cctgtgtcgg atttgaagga gttctggcaa
    17281 tatgctaaaa agaagacaat tgtttttggt ctgccatata ttttctattc gatcattcac
    17341 tttggtcttc aaaaagttgc aggggcatct gttcgtgttc ctacaaccat atctgatttg
    17401 ctaaatatct ataaagatcc tcttggagtt tcgtggtatt tatatatact ctggtcgatt
    17461 ttgataatct atggattatt gtctatttta gtcaaaaatc gtagaatgtt atttttgata
    17521 agtgttttcg cttattgttt aaccctattt gttcaaacag atatttatat tattcaaaga
    17581 acgctagttt gggggctttg tttctttctt ggcagtgtat tgaatgaaat tcactttgat
    17641 aaaattaatt tgaaaaaatt tcttttttta tttgtgctat ttgattttat ttatatgttc
    17701 gcttggttct tgttttatga agtagggtct aagaaggatt atgtaagcta tagtaactca
    17761 ggtttgtggg ggattgcttt tgttgtctgt gtattagttg cttttgcgat ttttccgaaa
    17821 atggagaaaa attttcctaa aactttccta tatttcacta aatacgggaa agatagttta
    17881 gggatttata ttcttcatgc accaatttgt agcatgattc ggattctaat gttgaaagtg
    17941 ggaataaact cagtttttct tcacgttgtt gttgggattg tgctaggctg gtatttatcc
    18001 atactagcaa cttatatatt gaaaaaaatt ccatttttga atattgtttt attaccacaa
    18061 aagtatatta aattaaaagg ctctttgtca actgtagtgg gttgaagtca gctaagctcg
    18121 agaaaggaca aattttgtcc tttctttttt gatattcagg gcgataaaaa tccgtttttt
    18181 gaagttttca aaggtaagcg cgtcataaca aggtatttat cattcatgga agacctcctg
    18241 tatactatta gtaaagtaaa actattggag gatattgtaa tgccacaacc tattgttcct
    18301 gtagagattc cacaatctcg tcgttttgat tctaaaaaga gaaatgatat tctgcttaaa
    18361 attcgtattg gcaagcttga agtaagtttt tttcaatctc tcaatctcga aatgatagaa
    18421 cagcttttgg ataaggtgtt gctctatgac aattcatcta tctagcctag ggcaggtcta
    18481 tctcgtatgt gggaaaacgg atatgaggca aggcattgat tcactggctt atctggttaa
    18541 aacccacttt gaattagatc ctttctcagg tcaagttttt ctcttttgtg gtggacgtaa
    18601 agaccgcttt aaagcccttt actgggatgg tcaaggattt tggctattat agtggattta
    18661 aactagaata gtacacctct gcttctaaaa cattgttaga aatcgatttg actgtcctgt
    18721 tcttatttca ttttactata aattcatcag aaagtcgtga tttctattga aatgaggact
    18781 ttctttttat actcatctgc tttcaaaaag cattctagtc catctccgat taacgatgga
    18841 ctttatcacc tccttctcca gtccttgtat gacatcttgg agttgattca tgacatcttc
    18901 caaagttcga aaggccttat tcttaaatcc acgtttacga atctctttcc acacttgttc
    18961 aatggggttc atctctggtg tgtatggaag aataaatgca aagccaatat tagtcggaat
    19021 ctttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa gataatcatc
    19081 tggataagct tatgaaagct cctattccta aagccccttt ataacctctt gcgagagaga
    19141 ctattgactc agctcttact tcatgcagat gaaacctctt atcgggtctt agaaagtgat
    19201 agtcagctga cctactattg gacctttttg tctgggaaag ctgagaatca agcaatcacg
    19261 ctgtaccacc atgatcagcg tcggagtggt tcggtagtac aagaattcct aggagattat
    19321 tctggctatg tgcattgtga tatgttgcgg cagtaactta ggactttagt cctctagttc
    19381 tgcctatgcg atagcagtcc aaggcttagg agcaaggcga cgctaagctt ggtaaactgc
    19441 gaaccgctag aagcttatcg tcaactggaa gaagctgaac ttgttggatg ttgggcgcat
    19501 gtgagaagga agttttttga agcgccccgc aagcaagcgg ataaatcatc gttaggagct
    19561 aaaggtttag cttattgtga tcagttattt tccttggaaa gagactggga ggctttacca
    19621 gctgatgaac gactacggaa acgtcaagaa catctccagc ccctaatgga agacttcttt
    19681 gcttggtgcc gccgtcagtc agttttatcg ggttcaaaac taggaagggc aattgaatac
    19741 agcctcaagt atgaagaaac ctttaagacc attttgaaag acggacatct ggtcctttcc
    19801 aataatctag ctgaacgcgc cattaaatca ttggttatgg gacggagtaa aagagtccag
    19861 tggactcttt tagcctgagc tgagtttaaa aaagcgaggg tggttgtttt ctcaaagttt
    19921 tgaaggagct aaagcaagag ctattattat gagcttattg gaaacagcta aacgtcatca
    19981 attaaatagc gagaaatatc tattctatct tctagaatgt cttccaaacg aggaaactct
    20041 cgtaaacaaa gaggttttag agcctattta ccatggacta aagttgtacc agaaaagtgc
    20101 aaataagaaa tctccagatt aggaactatc cgtgagttct ctagtctgga gatttttcaa
    20161 tatacttcgt tattggacgg ttacgatatt catatttttt gcaaagatgt tgtttgaaaa
    20221 ataattttca aaaattctga aaattctgtt gacatctttc tgaaaagagt ctataatgga
    20281 gagaaagttt taaaggagaa aatgatgaaa agttcaaaac tatttgccct tgcgggcgtg
    20341 acattattgg cggcgactac tttagctgca tgctctggat caggttcaag cactaaaggt
    20401 gagaagacat tctcatacat ttatgagaca gaccctgata acctcaacta tttg
//
