LOCUS       CR931682               22696 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 1772/40 (serotype 22f).
ACCESSION   CR931682
VERSION     CR931682.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22696)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22696)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22696
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="1772/40"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC22F_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC22F_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI33784.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..461
                     /gene="aliB"
                     /locus_tag="SPC22F_0002"
                     /pseudo
     CDS             293..461
                     /gene="aliB"
                     /locus_tag="SPC22F_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(462..974,976..1305))
                     /gene="tnp"
                     /locus_tag="SPC22F_0003"
                     /pseudo
     CDS             complement(join(462..974,976..1305))
                     /gene="tnp"
                     /locus_tag="SPC22F_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(915..974,976..1287))
                     /gene="tnp"
                     /locus_tag="SPC22F_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 6e-23"
                     /pseudo
     gene            1536..2981
                     /gene="wzg"
                     /locus_tag="SPC22F_0004"
     CDS             1536..2981
                     /gene="wzg"
                     /locus_tag="SPC22F_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33787.1"
                     /db_xref="GOA:Q4K0M6"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K0M6"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1536..1652
                     /gene="wzg"
                     /locus_tag="SPC22F_0004"
                     /note="Signal peptide predicted for SPC1138 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1740..2087
                     /gene="wzg"
                     /locus_tag="SPC22F_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 6.7e-65"
     misc_feature    2265..2708
                     /gene="wzg"
                     /locus_tag="SPC22F_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 5.7e-70"
     gene            2983..3714
                     /gene="wzh"
                     /locus_tag="SPC22F_0005"
     CDS             2983..3714
                     /gene="wzh"
                     /locus_tag="SPC22F_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33788.1"
                     /db_xref="GOA:Q4K0M5"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K0M5"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    2986..3594
                     /gene="wzh"
                     /locus_tag="SPC22F_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 6.1e-37"
     gene            3720..4415
                     /gene="wzd"
                     /locus_tag="SPC22F_0006"
     CDS             3720..4415
                     /gene="wzd"
                     /locus_tag="SPC22F_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33789.1"
                     /db_xref="GOA:Q4K0M4"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K0M4"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKL
                     DMPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQI
                     PLLGVVPDLNKMK"
     misc_feature    3720..3836
                     /gene="wzd"
                     /locus_tag="SPC22F_0006"
                     /note="Signal peptide predicted for SPC1140 by SignalP 2.0
                     HMM (Signal peptide probability 0.625) with cleavage site
                     probability 0.411 between residues 39 and 40"
     misc_feature    3741..4157
                     /gene="wzd"
                     /locus_tag="SPC22F_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 5.8e-56"
     misc_feature    4263..4340
                     /gene="wzd"
                     /locus_tag="SPC22F_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4425..5114
                     /gene="wze"
                     /locus_tag="SPC22F_0007"
     CDS             4425..5114
                     /gene="wze"
                     /locus_tag="SPC22F_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33790.1"
                     /db_xref="GOA:Q4K0M3"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K0M3"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVDEVNRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            5130..6497
                     /gene="wchA"
                     /locus_tag="SPC22F_0008"
     CDS             5130..6497
                     /gene="wchA"
                     /locus_tag="SPC22F_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33791.1"
                     /db_xref="GOA:Q4K0M2"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K0M2"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVFM
                     RDGAK"
     misc_feature    5130..5222
                     /gene="wchA"
                     /locus_tag="SPC22F_0008"
                     /note="Signal peptide predicted for SPC1142 by SignalP 2.0
                     HMM (Signal peptide probability 0.902) with cleavage site
                     probability 0.355 between residues 31 and 32"
     misc_feature    5913..6494
                     /gene="wchA"
                     /locus_tag="SPC22F_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 2.8e-159"
     gene            6528..7700
                     /gene="wchF"
                     /locus_tag="SPC22F_0009"
     CDS             6528..7700
                     /gene="wchF"
                     /locus_tag="SPC22F_0009"
                     /note="member of homology group 15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33792.1"
                     /db_xref="GOA:Q4K0M1"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q4K0M1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTSKSILKPDDEKVRNWYQEKGVAEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKDTGFDKDPRV
                     KFVGTVYDQELLKYIRENAFTYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGAISELDERSSQRIADAFTWEKIVSDYEEVFKG"
     gene            7704..8861
                     /gene="wcwA"
                     /locus_tag="SPC22F_0010"
     CDS             7704..8861
                     /gene="wcwA"
                     /locus_tag="SPC22F_0010"
                     /note="member of homology group 63"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33793.1"
                     /db_xref="GOA:Q4K0M0"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K0M0"
                     /translation="MKRILYLHAGAEMYGADKVLLELIKGLNPQEFEAHIILPNDGVL
                     VEALRQVGAQVSVLDYPILRRKYFNPKGILEYLKFYRRYSQKIAQYVRENGIDLVHNN
                     TTAVLEGIYLKRKVKLPLIWHVHEIIVKPKAISDFINFLMGRYADKIVTVSQAVASHV
                     KQSPFIKEGQVQVIYNGVDNAIYHPMQSSAVREKFGIPEDALVIGMVGRVNAWKGQGD
                     FLEAVTPILEHNPNSVAFLAGSAFAGEEWRVEELESKISKSSVASQIKRIEYYEHTTE
                     LYNMFDIFVLPSTNPDPLPTVVLEAMACGKPVVGYRHGGVSEMVVEGTNGLLAIPGQS
                     QELSDAILELVSDPEKRLQFGQASVRRQGESFSLESYIRSFSELYKSYKNE"
     misc_feature    8265..8786
                     /gene="wcwA"
                     /locus_tag="SPC22F_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 2.7e-32"
     gene            8854..9492
                     /gene="wcwC"
                     /locus_tag="SPC22F_0011"
     CDS             8854..9492
                     /gene="wcwC"
                     /locus_tag="SPC22F_0011"
                     /note="member of homology group 48"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI33794.1"
                     /db_xref="GOA:Q4K0L9"
                     /db_xref="InterPro:IPR015037"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L9"
                     /translation="MNKEIIKNKLKLIVYPIINFISRRRLKNKKFTIICDNCWAGKVY
                     QELGLPYQTPFIGMFVFSPDYIKMLKNLKYYLSGNISLKFVKESKHIENFDNAYPIAL
                     LDDIELHFLHYADEKEATQKWQRRLERIHWDNLYFKFNDNDACTYDLMREFDQLPYKS
                     KVIFSSKNYSDLHSLTYFKEKEKDCSVGIDLKIYHRYFDVVRWLNEGGVDLS"
     gene            9524..10768
                     /gene="ugd"
                     /locus_tag="SPC22F_0012"
     CDS             9524..10768
                     /gene="ugd"
                     /locus_tag="SPC22F_0012"
                     /note="member of homology group 20"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAI33795.1"
                     /db_xref="GOA:Q4K0L8"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L8"
                     /translation="MSKMKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINNK
                     ISPIQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDSERNFFDTSAVES
                     VIQQVQNVNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSR
                     IIVGTDLNDQKLIEKAQVFSNLLVQGAIKKDIPILIMGFTEAEAVKLFANTYLALRVS
                     YFNELDTYAETKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYEN
                     IPEELIGAIVRSNATRKDFIAKQVLKMVNYNNPEDDISVRQMDKEVVIGIYRLTMKSN
                     SDNFRQSSIQGVMKRIKDRGAKVIIFEPTLKDNGTFFGNAVINDLEEFKAKCDAIIAN
                     RYDEMLNDVKDKVYTRDIFRRD"
     misc_feature    9524..9613
                     /gene="ugd"
                     /locus_tag="SPC22F_0012"
                     /note="Signal peptide predicted for SPC1146 by SignalP 2.0
                     HMM (Signal peptide probability 0.931) with cleavage site
                     probability 0.611 between residues 30 and 31"
     misc_feature    9533..10045
                     /gene="ugd"
                     /locus_tag="SPC22F_0012"
                     /note="HMMPfam hit to PF01210, NAD-dependent
                     glycerol-3-phosphate deh, score 0.00017"
     misc_feature    9533..10090
                     /gene="ugd"
                     /locus_tag="SPC22F_0012"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.2e-45"
     misc_feature    10118..10399
                     /gene="ugd"
                     /locus_tag="SPC22F_0012"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 5e-38"
     misc_feature    10496..10747
                     /gene="ugd"
                     /locus_tag="SPC22F_0012"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.1e-06"
     gene            10776..11900
                     /gene="wcwV"
                     /locus_tag="SPC22F_0013"
     CDS             10776..11900
                     /gene="wcwV"
                     /locus_tag="SPC22F_0013"
                     /note="member of homology group 165"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33796.1"
                     /db_xref="GOA:Q4K0L7"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L7"
                     /translation="MKKVLIVRSGPYQVTPNEYNLQELGLASALSQQGYQCDVMYYHK
                     TKNYDQLFEKNGEKIKVFWRRGIRLFRSGIYPQILKKKFLSQYDKIIISEYSQIMAVL
                     LSRIHSNVYIYNGPYYNLFKIPIIESMYDFLFVRMLNKRTKTVFCKTEKAKHYLKNKG
                     FNDCKVVGVGLDVEKFEQEEEPTENTIELLKRMENKQNILYVGSLSKRKNTAHLIRIF
                     NILKSKSGKKNELQLVLIGKDEGNIVEKINYSRFKDDIIYQPYLKNSQLQFIYPSSQL
                     FVLPSIQEIFGMVLLEAMYFKLSVVSSASAGGETLIQDGINGKIMNDFNDEHWVDCIE
                     NLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDER"
     misc_feature    11322..11834
                     /gene="wcwV"
                     /locus_tag="SPC22F_0013"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 5.1e-24"
     gene            11909..12751
                     /gene="whaB"
                     /locus_tag="SPC22F_0014"
     CDS             11909..12751
                     /gene="whaB"
                     /locus_tag="SPC22F_0014"
                     /note="member of homology group 120"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33797.1"
                     /db_xref="GOA:Q4K0L6"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L6"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGNYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKANMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKKLNRVSAADPIGYQENVILHGSCVIFSPLYVSEEEFAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     misc_feature    11918..12460
                     /gene="whaB"
                     /locus_tag="SPC22F_0014"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 3.7e-13"
     gene            12781..14061
                     /gene="wzy"
                     /locus_tag="SPC22F_0015"
     CDS             12781..14061
                     /gene="wzy"
                     /locus_tag="SPC22F_0015"
                     /note="member of homology group 166"
                     /codon_start=1
                     /transl_table=11
                     /product="opolymerase"
                     /protein_id="CAI33798.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L5"
                     /translation="MNLSMLALTIGSVVFVKKTYRTFLNPIILFAILWFIITTLSNLK
                     LFQLFEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFF
                     LLGIICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVIPSAMV
                     LEILGILDFWSNKKGRKLFYLNLAVIFVRVVADAGRTPLFNVVIYLLLTVLANRFSEK
                     TEKKRKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSILD
                     SEKLVTKGLVSLNGFFFSISYVLKNLFRIGYSQRVLEAYTMIANTDAIWYNIAPGLTK
                     ANAYVSLFWFFYADGRLLGVLIGSLLYGAFCGYIFCRYIQQQNKKNLAMLLFIYQGVF
                     FSFIRFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            14054..15061
                     /gene="wcwX"
                     /locus_tag="SPC22F_0016"
     CDS             14054..15061
                     /gene="wcwX"
                     /locus_tag="SPC22F_0016"
                     /note="member of homology group 167"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAI33799.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L4"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNEVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            15066..16508
                     /gene="wzx"
                     /locus_tag="SPC22F_0017"
     CDS             15066..16508
                     /gene="wzx"
                     /locus_tag="SPC22F_0017"
                     /note="member of homology group 47"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI33800.1"
                     /db_xref="GOA:Q4K0L3"
                     /db_xref="InterPro:IPR002528"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L3"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKEEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLVNLRKYNIRFSFNNIKIRRHLKPIFVLL
                     GSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNSMKLVKLLITVITAIGGVLLPRLSDYY
                     SKGEFEKLNHIVDKVFRIMLFLFLPAQVALILVAPVIMPILFGDSFIPAVLTLQLTSL
                     LICTLGFSNLFGTQILLTFGDERKLLISTILGALSNIALNLILIPVMAQNGAALASVI
                     SETIVTLTAYYYAKKRVTIRFDLGFYLPTVVSTIIMGGAIYVVMQLYIGDIEKMLFST
                     LLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
     misc_feature    15084..15893
                     /gene="wzx"
                     /locus_tag="SPC22F_0017"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 5e-47"
     gene            16511..17611
                     /gene="glf"
                     /locus_tag="SPC22F_0018"
     CDS             16511..17611
                     /gene="glf"
                     /locus_tag="SPC22F_0018"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI33801.1"
                     /db_xref="GOA:Q4K0L2"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L2"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     misc_feature    16946..17548
                     /gene="glf"
                     /locus_tag="SPC22F_0018"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 4.4e-138"
     gene            17638..18507
                     /gene="rmlA"
                     /locus_tag="SPC22F_0019"
     CDS             17638..18507
                     /gene="rmlA"
                     /locus_tag="SPC22F_0019"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI33802.1"
                     /db_xref="GOA:Q4K0L1"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4K0L1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    17641..18357
                     /gene="rmlA"
                     /locus_tag="SPC22F_0019"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 1.4e-119"
     gene            18508..19101
                     /gene="rmlC"
                     /locus_tag="SPC22F_0020"
     CDS             18508..19101
                     /gene="rmlC"
                     /locus_tag="SPC22F_0020"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI33803.1"
                     /db_xref="GOA:Q7BTQ6"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q7BTQ6"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     misc_feature    18544..19074
                     /gene="rmlC"
                     /locus_tag="SPC22F_0020"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 8.8e-16"
     gene            19114..20163
                     /gene="rmlB"
                     /locus_tag="SPC22F_0021"
     CDS             19114..20163
                     /gene="rmlB"
                     /locus_tag="SPC22F_0021"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI33804.1"
                     /db_xref="GOA:Q4K121"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K121"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    19129..20085
                     /gene="rmlB"
                     /locus_tag="SPC22F_0021"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 7.1e-05"
     misc_feature    19132..19872
                     /gene="rmlB"
                     /locus_tag="SPC22F_0021"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 2.7e-76"
     misc_feature    19132..19968
                     /gene="rmlB"
                     /locus_tag="SPC22F_0021"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0039"
     misc_feature    19135..19947
                     /gene="rmlB"
                     /locus_tag="SPC22F_0021"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.6e-05"
     gene            20229..21080
                     /gene="rmlD"
                     /locus_tag="SPC22F_0022"
     CDS             20229..21080
                     /gene="rmlD"
                     /locus_tag="SPC22F_0022"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI33805.1"
                     /db_xref="GOA:Q4K1G6"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1G6"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    20229..21077
                     /gene="rmlD"
                     /locus_tag="SPC22F_0022"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 4e-147"
     misc_feature    20232..20861
                     /gene="rmlD"
                     /locus_tag="SPC22F_0022"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.9e-19"
     misc_feature    20232..20873
                     /gene="rmlD"
                     /locus_tag="SPC22F_0022"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00013"
     misc_feature    20235..20963
                     /gene="rmlD"
                     /locus_tag="SPC22F_0022"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2.9e-08"
     gene            order(21125..21223,21227..22310)
                     /gene="glf"
                     /locus_tag="SPC22F_0023"
                     /pseudo
     CDS             join(21125..21223,21227..22027,22020..22310)
                     /gene="glf"
                     /locus_tag="SPC22F_0023"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
     misc_feature    join(21563..22020,22027..22166)
                     /gene="glf"
                     /locus_tag="SPC22F_0023"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 4.2e-112"
                     /pseudo
     gene            22544..>22696
                     /gene="aliA"
                     /locus_tag="SPC22F_0024"
     CDS             22544..>22696
                     /gene="aliA"
                     /locus_tag="SPC22F_0024"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33807.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYL"
     misc_feature    22544..22630
                     /gene="aliA"
                     /locus_tag="SPC22F_0024"
                     /note="Signal peptide predicted for SPC1158 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
BASE COUNT     7377 a   3555 c   4697 g   7067 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attctcgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga aaatgaacat
      301 aaagaagcgt gtccttagtg caggtctgac ttttgcatct gctttgcttt tagctgcttg
      361 cgaccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaattac ctgttagact attacgctga taatatagtc aattgaaaca agagcaggac
      481 aaaagagcct cgtaaaaggt attgcaactt ggtaatacct tttacgaggc tttttgatat
      541 gagcccatgt tttctcaata ggattgtact caggtgagta gggaggaaga aggtaaaagt
      601 ttatgcccaa actcttcgca taaaagttct agcttcccca ttctatggaa tcttgcatta
      661 tccataataa taaccgatgg tgtggttaat gttggtaaga gaaacttctg aaaccaagct
      721 tcaaaaaagt cgctcgtaat cgtctcttcg taagtcattg gagcgattaa ctcaccattt
      781 gttagacctg caaccaaaga aatcctctga tatcttcttc ttaactgacc ttttaaagag
      841 cgaccatatt ctcgataaaa ataagtatca aatcctgttt cgtcaatcta aacagctgct
      901 aggtgcttta aactattaaa attcttaaga aataaggcta ctttttctgg gtcttgttca
      961 tagtaggtgt ggttcttttt ttcgagtgta gcccatagct ttgagcgcat agtggatggt
     1021 agttggatga cagccaaatt cagaagctat ttcagtcaaa taagcgtctg gattatcagt
     1081 aagatagttt ttaagtctat ctctatcaac ttttcttggt tttattcctt ttacttggtg
     1141 gtttagctct cctgttttct cttttagctt taaccagcca taaatggtat tacgtgagat
     1201 ttggaaaacg tgtgatgctt ctgttatact acctgttcgc tcacaataag agagaacttt
     1261 tttacgaaaa tctattgaat atgccataaa aagattatac cacattgtgt actatattag
     1321 attgaaacta gagtagtaca cctctgcttc taaaaaattt ttagaaatcg atttaactgt
     1381 cctgatcgat ttgtcatgtt cttatttcat tttactatat ttttgtttcg cgggaagtct
     1441 actaagatac ttaaagatgc agatagtaaa aaaatgtaga cattaccgta aaaaagtgat
     1501 ataattgtac gatgttcaag gtataggtgt taatcatgag tagacgtttt aaaaaatcac
     1561 gttcacagaa agtgaagcga agtgttaata tcgttttgct gactatttat ttattgttag
     1621 tttgtttttt attgttctta atctttaagt acaatatcct tgcttttaga tatcttaacc
     1681 tagtggtaac tgcgttagtc ctactagttg ccttggtagg gctactcttg attatctata
     1741 aaaaagctga aaagtttact atttttctgt tggtgttctc tatccttgtc agctctgtgt
     1801 cgctctttgc agtacagcag tttgttggac tgaccaatcg tttaaatgcg acttctaatt
     1861 actcagaata ttcaatcagt gtcgctgttt tagcagatag tgatatcgaa aatgttacgc
     1921 aactgacgag tgtgacagca ccgactggga ctgataatga aaatattcaa aaactactag
     1981 ctgatattaa gtcaagtcag aataccgatt tgacggtcga ccagagttcg tcttacttgg
     2041 cagcttacaa gagtttgatt gcaggggaga ctaaggccat tgtcttaaat agtgtctttg
     2101 aaaatatcat cgagtcagag tatccagact acgcatcgaa gataaaaaag atttatacca
     2161 agggattcac taaaaaagta gaagctccta agacgtctaa gaatcagtct ttcaatatct
     2221 atgttagtgg aattgacacc tatggcccta ttagttcggt gtcgcgatca gatgtcaata
     2281 tcctgatgac tgtcaatcga gataccaaga aaatcctctt gaccacaacg ccacgtgatg
     2341 cctatgtacc aatcgcagat ggtggaaata atcaaaaaga taaattaacc catgcgggca
     2401 tttatggagt tgattcgtcc attcacacct tagaaaatct ctatggagtg gatatcaatt
     2461 actatgtgcg attgaacttc acttctttct tgaaaatgat tgacttattg ggaggggtag
     2521 atgttcataa tgatcaagag ttttcagctc tacatgggaa gttccatttc ccagtaggga
     2581 atgtccatct agactctgag caggctctag gttttgtacg tgaacgctac tcactagccg
     2641 atggagaccg tgaccgtggt cgcaaccaac aaaaggtgat tgtggctatc cttcaaaaat
     2701 taacgtcaac cgaagcactg aaaaattata gtacgatcat taatagcttg caagattcta
     2761 tccaaacaaa tatgccactt gagactatga taaatttggt caatgctcag ttagaaagtg
     2821 gagggaatta taaagtaaat tctcaagatt taaaagggac aggtcggacg gatcttcctt
     2881 cttatgcaat gccagacagt aacctctatg tgttggaaat agatgatagt agtttagctg
     2941 tagttaaagc agctatacag gatgtgatgg agggtagatg aaatgataga catccattcg
     3001 catatcgttt ttgatgtaga tgacggtccc aagtcaagag aggaaagcaa ggctctcttg
     3061 gcagaatcct acaggcaagg ggtacgaatc attgtctcta cctctcaccg tcgcaagggc
     3121 atgtttgaaa ctccggaaga gaagatagca gaaaactttc ttcaggttcg ggaaatagct
     3181 aaggaagtgg cgagtgactt ggtcattgct tacggagctg aaatttacta cacaccagat
     3241 gttctggata agctggaaaa aaagcggatt ccgaccctca atgatagtcg ttatgccttg
     3301 atagagttta gtatgaacac tccttatcgc gatattcata gcgccttgag caagatcttg
     3361 atgttgggaa ttactccagt cattgcccac attgagcgct atgatgctct tgaaaataat
     3421 gaaaaacgcg ttcgagaact gatcgatatg ggctgttaca cgcaagtaaa tagttcacat
     3481 gtcctcaaac ccaaactttt tggcgaacgt tataaattca tgaaaaaaag agctcagtat
     3541 tttttagagc aggatttggt tcatgtcatt gcaagtgata tgcacaatct agacggtaga
     3601 cctcctcata tggcagaagc atatgacctt gttacccaaa aatacggaga agcgaaggct
     3661 caggaacttt ttatagacaa tcctcgaaaa attgtaatgg atcaactaat ttaggagaaa
     3721 tgatgaaaga acaaaacacg atagaaatcg atgtatttca attatttaaa accttgtgga
     3781 aacgcaagct aatgatttta atagtggcac ttgtgacagg tgcgggggct tttgcatata
     3841 gcacttttat tgttaagcca gaatatacga gtaccacgcg aatttacgta gtgaatcgcg
     3901 atcaaggaga caagccgggg ctgacaaatc aggatttgca ggcaggatct tatctggtaa
     3961 aagactaccg tgagattatc ctttcgcaga atgtattgga aaaagtagcg acaaatttga
     4021 agttggatat gccaacaaaa acgttagcca gcaaagttaa agtgactgta ccaactgaca
     4081 ctcgtatcgt ctcaatctct gtcaaagata aacaaccaga agaagccagt cgtatcgcta
     4141 attctctacg agaagttgct gcagaaaaga tcgtcgctgt aacgcgagta tctgatgtaa
     4201 cgacacttga agaagcgcga ccagctacga ctccctcttc tccaaatgtt cgacgcaatt
     4261 ccttgtttgg ttttcttgga ggagcagtcg taacagtaat tgctgttctt ttgattgagt
     4321 tgctcgacac ccgtgtgaaa cgtcctgaag atgtcgaaga tgtactgcaa attccacttt
     4381 taggggtcgt tccagatttg aacaaaatga aataggagga agttatgcca acattagaaa
     4441 tctcacaggc aaaattggat tttgtaaaaa aggcagagga atattataac gctttgtgca
     4501 cgaacctaca gttaagtgga gatgatttga aagtattttc tatcacttct gtgaaactag
     4561 gagaaggaaa atcaacgact tccaccaata tcgcttgggc ttttgcgcat gcaggttaca
     4621 aaacgctgct gattgatgga gatattcgca attctgttat gttaggtgtc tttaaagcaa
     4681 gggataagat tacaggcctg acagaatttt tatcaggaac tacagaccta tcacaagggc
     4741 tttgtgatac caatgtcgaa aatctctttg taattcaggc tggctctgtg tcaccgaatc
     4801 cgacagctct tcttcaaagt aagaatttca gtacaatgct tgaaaccttg cgtaaatatt
     4861 ttgactacat cattgtagat actgctcctg tcggtgtcgt gattgatgcg gctattatta
     4921 cgcgaaaatg cgatgcttct attttagtga cggaggtaga tgaagtaaat cgacgggata
     4981 ttcaaaaagc aaaagaacag ttggaacaca caggaaagcc gtttttggga gttgtgttga
     5041 ataaattcga tacttcagta gacaaatacg gttcttatgg aaattatgga gattacggga
     5101 aaaataaaaa ataggtcggg ggattagaga tgaatggaaa aatagtaaag tcttcattgg
     5161 ccataatcca gagttttctt gttattttat tgacttatct acttagtgct gtgagagaag
     5221 cggagattgt ttcaacaaca gctattgcac tttatatcct ccattatttt gtcttttata
     5281 tcagtgatta tggacaggat ttctttaaaa gaggatattt gattgaactt gtccagacat
     5341 tgaaatatat cctattcttt gcactagcga ttagtatttc taattttttc ttagaggatc
     5401 gatttagtat ttccagacga ggcatgattt acttcctcac attacatgct ctcttagtct
     5461 atgtgctaaa cctatttatc aagtggtatt ggaagcgggc ttatcccaac tttaaaggaa
     5521 gtaagaagat tctcctactt acagcaactt ctcgtgtcga aaaggtactg gatagattaa
     5581 tagaatcaaa tgaggttgtt ggggagttgg tagccgtcag tgtcttagat aaaccagatt
     5641 ttcagcatga ttgtttaaag gtagtagcag agggggagat agtaaacttt gcgactcatg
     5701 aggtggtcga tgaagtcttt atcaatcttc caagtgaaaa atacaatatt ggagagcttg
     5761 tctctcagtt tgaaacgatg ggaattgatg taacagttaa tctaaatgct tttgatcgta
     5821 gtttggcacg taacaagcaa attcgtgaga tggcaggatt aaacgttgtg actttttcta
     5881 caacatttta taagactagt catgtaattg ctaagcggat tattgatatc atgggtgcat
     5941 tggtagggct gatactatgt ggtttagtca gtattgtact ggttcctttg attcgaaagg
     6001 atgggggctc tgctattttt gctcagacgc gtataggaaa aaatggtcgt cagttcactt
     6061 tttataagtt tcgctctatg tgtgtagatg ccgaggcgaa aaaaagagaa ctcatggaac
     6121 aaaataccat gcagggtgga atgtttaagg tggacgatga tcctcgtatc acgaaaattg
     6181 gtcgttttat acggaagact agcttggacg agctaccaca gttttataat gttctaaagg
     6241 gagatatgag tttggttggc acacggccac caacagtgga cgagtatgaa cactataccc
     6301 cagaacaaaa acgtcggcta agttttaaac ctggtataac aggcttatgg caggtcagtg
     6361 gacgaagtga gattaagaat tttgatgaag ttgtcaaatt agatgtggcc tatatagatg
     6421 gttggacaat ttggaaagac attgaaattt tattgaagac agttaaagtt gtatttatga
     6481 gagatggagc gaagtgattt ttgcccttca gtcttgttag gagagatatg aaacagtcag
     6541 tttatatcat tggttcaaag gggattcctg ccaagtatgg aggatttgaa acctttgttg
     6601 agaaattaac agaatatcaa aaagatggta acatccaata ctatgttgcc tgcatgcgcg
     6661 aaaattctgc aaagtcagga tttacagcag acacatttga gtacaacggt gctatttgtt
     6721 acaacattga tgtgcctaat attggtcctg ctagagccat tgcttacgat attgcagcgg
     6781 tcaataaggc tattgaattg tctaagggaa acaaggacga ggctcccatt ttttacattc
     6841 tagcttgtcg tatcggacct tttatttctg gacttaagaa aaaaattcgt tcgatcggag
     6901 gccgtttgct ggtaaatcca gatggtcatg agtggcttcg agctaaatgg agcttgccag
     6961 ttcggaagta ttggaaattt tcggaacagt tgatggtcaa acatgcagat ttattagtct
     7021 gtgatagcaa aaatatcgaa aaatatattc gagaggacta taaacagtat cagcccaaga
     7081 cgacttatat cgcctatgga acagatacaa gcaagtctat tttaaaacct gatgacgaaa
     7141 aagttcgtaa ttggtatcag gaaaaaggcg ttgctgaaaa cggatattat ctagttgtgg
     7201 gacgatttgt tcccgaaaac aactatgaaa ccatgattcg tgaatttatc aagtctaagt
     7261 ccaataagga ctttgtcctt attacaaatg tagaacaaaa taaattttac gatcagttgc
     7321 tcaaggatac aggctttgac aaagacccga gagtcaaatt tgttgggact gtctatgatc
     7381 aagaattgct caaatatatc cgagagaatg cttttaccta cttccatggc catgaagttg
     7441 gtgggacaaa cccatcgctt ttagaagctc ttgcttcaac aaagcttaat ttactgctag
     7501 atgttggctt taaccgtgaa gttggtgagg atggagccat ttactggaaa aaagatgagc
     7561 tagcgcatgt aatcgaagaa gtggaacgat ttgatgaagg tgctatttcg gaattagacg
     7621 aaaggtctag ccaacgaatt gcggatgcat ttacgtggga aaagattgtg tcagattatg
     7681 aggaagtgtt taaaggatag agaatgaaac ggattttata tttacatgct ggtgcagaaa
     7741 tgtatggagc agataaggtt ttattggaat tgatcaaagg attaaatcct caagaatttg
     7801 aagctcatat tatcctgcct aatgacggtg ttttagtcga agccctacgc caagttggcg
     7861 ctcaggttag cgtgttggat tatccgattt tacgtagaaa atactttaat cctaaaggga
     7921 ttttggaata tctgaaattt tatcgtcgtt actcccaaaa aattgcccaa tatgtgcgtg
     7981 aaaatggaat agatcttgta cataacaata caacagctgt cttggaagga atctatctca
     8041 aaagaaaggt gaaacttccc ttgatctggc acgttcatga gattattgtt aagcccaagg
     8101 ctatttcaga ttttattaac ttcttgatgg ggcgttatgc agataagatt gtaacagtct
     8161 ctcaagctgt ggccagtcat gtcaaacagt ctccctttat caaagagggt caggttcagg
     8221 ttatctataa cggagtggac aatgcgatct atcatccgat gcagtcaagt gcagtgcgtg
     8281 aaaaatttgg gatcccagag gatgctctcg tcattggtat ggttggacgt gtcaacgcgt
     8341 ggaaggggca aggagatttt ctagaagctg tgacaccgat tttggagcat aatccgaatt
     8401 ccgtagcttt tctagcgggg agtgcctttg ctggtgaaga gtggcgagtt gaagaattag
     8461 agtctaagat ttccaaatca agtgtagcct cacaaatcaa acgaattgaa tattatgagc
     8521 atacgactga actttataat atgtttgata tctttgtctt accaagtacc aatcccgatc
     8581 cactaccaac agtggtacta gaggctatgg cttgtggtaa gccagtagtc ggctaccgtc
     8641 atggtggtgt ctctgaaatg gttgttgaag gaaccaatgg cttactggca atcccaggac
     8701 aatcacaaga actatcggat gcgattttgg agttggtttc tgatccagaa aaacggctcc
     8761 aatttggcca agcatcagta agaagacaag gagaatcgtt ttctttggaa tcttatatcc
     8821 gtagtttctc agaattatat aagagttata aaaatgaata aagaaataat aaagaataaa
     8881 ttaaaactaa ttgtttatcc tatcattaat tttatttcta ggagaagatt aaaaaataaa
     8941 aaattcacca ttatttgtga taattgttgg gctggaaaag tgtaccaaga gttaggtttg
     9001 ccctaccaaa caccctttat cgggatgttt gttttttcgc ctgattatat caagatgctc
     9061 aagaatttga aatactattt gagcggaaat atctcgttga aatttgttaa ggaatcaaag
     9121 cacattgaaa actttgataa tgcttatcca attgcactcc ttgacgatat cgagcttcat
     9181 ttcttgcact atgcagatga aaaagaggct actcagaaat ggcaacgtcg tttagaaaga
     9241 attcattggg ataatttgta ttttaagttc aatgacaatg atgcttgtac ctatgacctt
     9301 atgagagaat ttgatcaatt accgtacaaa agtaaagtca ttttttcatc taagaattat
     9361 tctgatttac attcattaac ttattttaaa gagaaggaaa aagattgtag tgttggaatt
     9421 gatcttaaaa tctatcatcg ttatttcgat gttgtaaggt ggctgaatga aggcggagtg
     9481 gacttgagtt aatcagatta aaactaaaaa aggagttgtt aatatgtcta aaatgaaaat
     9541 tgcagtagtt gggactggtt atgttggttt atccatttct gtgttacttg cacaacacca
     9601 tcatgtagta gcagtagata ttgtaaaaga gaaagtagaa ttaattaata ataaaatttc
     9661 acctattcag gatgatttta ttgaaagata tctttcagaa agtaatttag atttagttgc
     9721 aacaatagac gctgaaacag cttataaaga tgcctctttt atcgtagtag cgacgccaac
     9781 aaattatgac tcagaaagaa atttttttga tacatcagca gttgaatcgg ttattcaaca
     9841 ggttcagaat gtgaattcta cagcaactat agtaataaaa tcaacagtcc ccgtgggttt
     9901 tactgattca attcgtaaaa aattaggaat ttcaaatctt ctattcagcc ctgaattttt
     9961 gcgcgaatca agagcacttt atgataactt atatccaagt cggatcatag ttggaacaga
    10021 tttaaatgat caaaaattaa ttgaaaaggc ccaagttttc tctaatcttt tagtgcaagg
    10081 tgctatcaaa aaagatatcc ctattttaat tatgggattt actgaagctg aagcagttaa
    10141 attatttgct aatacctact tagcattgcg ggtatcatat tttaatgaat tagatactta
    10201 tgcagagacc aaaggactag atactcaaaa aataattgag ggtgttagtt tagatccccg
    10261 tatcggaacc cattataata atccgagctt tgggtacggt ggatattgct taccaaagga
    10321 cactaagcaa cttttagcta attatgagaa tatcccagaa gaacttattg gggctatagt
    10381 acgtagcaat gcaacacgta aggattttat tgctaaacaa gttcttaaaa tggtgaatta
    10441 taataatcca gaagacgata tttctgtcag acagatggat aaagaagttg ttattgggat
    10501 ataccgatta actatgaaaa gtaacagtga taactttcgt cagagttcaa tacagggagt
    10561 tatgaaacgt attaaggata gaggagctaa agtaattatt tttgagccta ctctaaaaga
    10621 taatggtacg ttctttggga acgctgttat aaatgattta gaagagttca aagcaaagtg
    10681 cgatgcgatt attgcaaatc gttatgatga aatgttgaac gacgttaagg ataaagtata
    10741 tacacgagat atcttcagaa gagattaata aaaatatgaa aaaagtatta attgtccgaa
    10801 gtggacctta ccaagttact ccaaatgaat acaaccttca ggagcttgga ttagcttctg
    10861 ctctcagtca gcagggatac caatgtgacg tgatgtatta tcacaaaaca aaaaactatg
    10921 atcaattatt tgagaaaaac ggggaaaaaa ttaaagtatt ttggagaagg ggaataagat
    10981 tatttagaag tggaatttat ccccagattt taaaaaagaa atttttgagt cagtatgata
    11041 aaataattat ttccgagtat agccagatta tggcagtttt attgtctaga attcattcca
    11101 atgtatatat ttataatggt ccatactata atctatttaa gatccccatt attgaatcta
    11161 tgtacgattt tctttttgta agaatgctca ataagagaac caagacagtt ttctgcaaga
    11221 cagaaaaggc aaagcattat cttaaaaata agggattcaa tgattgtaaa gtagtgggcg
    11281 taggtctaga tgttgaaaag tttgaacaag aagaggaacc tacggagaat actatagaac
    11341 ttttaaaaag aatggagaat aagcaaaata ttctttatgt aggctcacta tcaaaaagaa
    11401 aaaacacagc tcatttaatt agaattttta atattttaaa atctaaaagt ggtaagaaaa
    11461 acgaacttca attggtattg attggtaagg atgagggtaa tattgttgaa aaaattaact
    11521 attcacggtt taaagatgat attatttatc aaccttattt aaagaactct cagcttcaat
    11581 ttatttaccc atcatcacaa ctatttgtgc tcccgtcgat tcaagagatt tttggtatgg
    11641 tattacttga ggcaatgtat tttaagttgt ctgttgtttc cagcgcaagt gctggaggag
    11701 agacactgat tcaagatggt ataaacggta aaattatgaa tgattttaat gatgaacact
    11761 gggtggattg tatagaaaat ctattaaata acccattgga attgaaacgg cttggagaat
    11821 gtgcccataa gcgaattacg gaacagttta tgtggtcttc aattgcgaga aaaataattg
    11881 agacatttga tgaaaggtaa gacttactat gaatttttgt tttgtgattt tgcattatcg
    11941 taccagcaat gacactatag agtgtatcaa atcgattcaa aagcttgagg gaaattataa
    12001 aattgtaatt gttgataacg cttctcaaaa tggcagtata gaaagggtag aagccttatt
    12061 tgcaaataat gacgagatag ttataataaa aaacacgaaa aacttaggat ttgctgcagg
    12121 aaataatatt ggatacgcct atgctcggac tcaaataaaa gctaatatga ttgctgtact
    12181 taataatgat attgttatta agcaaaaaga tttcattaat cgtatatttg aactctatag
    12241 aaattctcag tttcatatcg ctggtccaga cattgtctct cttgtagatg gtcatcatca
    12301 aagtcctgtt gttgagaaga tcaattctat atctaaggca aataaagaac tttttaaata
    12361 tagaatcttg agaattatta ataaaatagg attatatgag ctgatgacta gacagccaaa
    12421 aaaaaaatta aatagagtaa gtgctgcaga ccctatagga tatcaggaaa atgttatttt
    12481 acatgggagt tgtgtaattt tttcaccatt atatgtttca gaggaggagt ttgcttttag
    12541 accagatacg ttcatgtata tggaagagcc tattctatat gaatattgca tgcttaaaaa
    12601 ttataagaca gtatttgatc cttctattgt aatttatcat aaagaggact catcaacaaa
    12661 ttcgttgtat aatgcggcat atgcaaaaag agagtttgtt tttaaaaata tgattagatc
    12721 tctaaagatt tatagaagtc tattgaagta gtaaactagg gaaaggatag taattaaaaa
    12781 ttgaatctta gtatgttagc cttgacaata ggatcagtgg tatttgttaa aaaaacgtat
    12841 aggacgtttc tcaatcccat aattttattt gcaattttgt ggtttattat aacaactttg
    12901 tcaaatttaa aactattcca acttttcgag attagtactc atacacaaca aattattttg
    12961 cttgggactt ctctatttgt tataggggga gggatagcaa tttggtttcg ggataaattt
    13021 tattttaaag ttggcggtaa ctcatatttt acaacagact ttgaaattaa ttataatttg
    13081 ttctttttgc taggtatcat ttgtcttttc tattatttgc cagatttctt ttcctcactg
    13141 gtatcattaa taagaggtgg gaatttaaac ttagttagac aatctgcgca ggatgcagta
    13201 gataccagtg gattaaagaa tttcattgga acatttattg ttattcctag tgccatggta
    13261 ttagaaatat taggaatatt agatttctgg agcaataaaa aaggcagaaa actattttat
    13321 cttaatttag ctgtcatttt tgtaagagtt gttgcagatg ctggtagaac gcctctattt
    13381 aatgttgtca tatatttatt acttactgtt ttagcaaata ggttctctga aaaaactgaa
    13441 aagaagagaa aagttagtaa aattaagata gtaaattatg gtatgctagg ttcaattatc
    13501 ttatggctat caactttatc taggacaaca acctccgttt ataggattct ttatttttat
    13561 ttcgcaatgt ccccaatact attagaaaag tggagtagta tacttgattc tgaaaaatta
    13621 gtaacaaagg gtttggtttc gttgaacggt ttcttttttt caatctcata tgtacttaaa
    13681 aatctgttta gaataggtta ttctcaaaga gtattagaag catacacaat gattgcgaat
    13741 actgatgcaa tctggtataa tattgcacct ggtttgacca aggcaaatgc atatgtctct
    13801 ctgttttggt ttttttatgc ggatggacgt ttattaggag ttttaatagg atcccttcta
    13861 tatggtgcct tttgtggcta tatcttttgc aggtatatcc agcaacaaaa taaaaagaat
    13921 ttggctatgt tactatttat ttatcaaggt gtttttttct cttttattag atttccgttt
    13981 tcaaaatcaa attatgcaat tgcattcgta ctcttattat tttttgcttt taagaagaaa
    14041 ggaatagaga aaagtgttta atatcaatga ccagtctatt atttatgttg catgtcctta
    14101 ttttaataaa acaggtggaa cggagctcgt ccatcaatta gtttattcta ttaatcattt
    14161 tggggggaaa gctatcgttg cttattatgg tagtgaaagt gctccaaatg aggtgaatcc
    14221 tgcgtttaga gaatatgttt ctacgtttgt tgatataaaa gatgttattg actctcttga
    14281 taatattatt attttaccgg aaattaatcc ggatttagcc gctaatctag agtctattca
    14341 aaaagcagta tggtggatga gcgttgacaa ttatttgaag cgtaatggta ttttaggttc
    14401 cttggaacat tttggacttt tacgaacaat taaattattt gtaaaaggaa atattaaaat
    14461 aggtggatat agaatagata aagagattcc ccatctttat caaagtgaat acgccaagca
    14521 atttcttcta gctaaaggtg tcaaaaagta ctatagattg tctgattatt taaacgagtc
    14581 ttatattcag cgatctattt caacagacac taaaaaagat gttattcttt acaatcctaa
    14641 aaaagggatt gaatttactc gtgagctaat taaacaggct ccagaattaa cgttctctcc
    14701 aattgagaat atgtcaactg aacaggtgaa aaaattactt tcaaaaagca aagtatatat
    14761 tgattttggc aaccatcctg ggaaagatag attcccacgg gaggcagcga tatcaggttg
    14821 ttgtgtgata actgggaaac gaggttctgc aaaatattat aaggatattc ctattccaga
    14881 ttcatacaaa tttgaagaca ctgttgaaaa tatccccaac attattgaga ccctgaaatc
    14941 atgcttaaaa aattatgaca aacatactgt tgactttgag aaatatcaac aatatattaa
    15001 atctgaacat gatttatttg aaagagatgt gaaagaatta ttcactagga ataggggtta
    15061 aggttatgtc aaccagaaat tcacttatta aaaattctct ttataatgtt gcttatagaa
    15121 tgttaaatat catatttcca ttagtatccg caacatatac tgcacggata attttagcta
    15181 gtggagttgg ggaggtctcg tttgcacaaa atgttgtttc ttactttaca acgatagctg
    15241 ctatgggtat tccaaattat ggtatacgag aaattgctaa aactagaaat aaagaagagg
    15301 ctacgaataa agttttttca gagctatttc tgattaatgg attgtctaca ttactgtgtt
    15361 ctatagtata tttaattctg attttgacat tcaatagcat ttttgataat acatcaatgt
    15421 atcttgctgt gggtttaaca ttagtgttta acttccttaa tatcgattgg ttctatcaag
    15481 gaaaagagga ctatgcatac atcacgaaac gtagtttcag tataaaactt atttctcttt
    15541 ttagtttatt tatttttgtt agagatactg acgatgcagt taactatgca ttgatttcta
    15601 gcttagcaat tggcgggaat aatattttta atcttgttaa tttaaggaaa tataatatta
    15661 gatttagttt taataatatt aagattagaa gacacttaaa acctattttt gttttgttgg
    15721 gttcagtgat tgctattgaa atctatacta tgctggatac cactatgatt ggtgctatgg
    15781 taggaacgac tgaggtaggt tattatacaa attctatgaa gctagttaaa ttgctgataa
    15841 ctgtgattac cgctattgga ggagtgcttt taccacgact aagtgattat tattctaagg
    15901 gagaatttga aaaattaaat cacatcgttg ataaagtttt tagaatcatg ttgtttcttt
    15961 ttttaccagc ccaagttgca ttaattctag ttgcaccagt aattatgccg attttatttg
    16021 gtgatagttt tataccagca gtgttaacac ttcaacttac ttctttgctt atatgtacat
    16081 tagggtttag taatttattt gggactcaaa tattactaac atttggagat gagcgaaagc
    16141 ttttgattag cacaatttta ggagcgctta gtaatatcgc tttgaaccta attctgattc
    16201 cagtaatggc tcaaaatgga gcagcgttgg catctgtgat tagtgaaaca attgttactt
    16261 taacagcata ctactatgcg aaaaaacgtg tgacaattag gtttgactta ggattttatt
    16321 tgccaactgt tgtttcaaca ataatcatgg gtggagctat atatgtagta atgcaattgt
    16381 atattgggga tatagaaaaa atgttatttt caactttgtt aggaggtgtt gtattccttt
    16441 taattaacgt ttttatgaag aatcctatta tatatgaatt tacaggtatt ataaagagaa
    16501 agagataatt atgtacgact atttaatcgt tggagcgggt ttgtctggag caatcttcgc
    16561 acacgaagct acaaagcgtg gaaaaaaagt aaaagtgatt gataaacgcg atcacattgg
    16621 agggaacata tactgtgaga atgtagaagg tatcaatgtt cataaatatg gtgcccatat
    16681 cttccatact tctaataaaa aagtctggga ctacgtcaat caatttgctg agtttaacaa
    16741 ctatatcaac tcacctgtcg caaactataa gggaagtctt tataaccttc ctttcaatat
    16801 gaataccttc tatgctatgt ggggcacaaa aactccacaa gaagtgaagg ataagattgc
    16861 tgagcagaca gctggtatga aggatgttga gccgaaaaat ctggaagaac aagctatcaa
    16921 gttgattggt ccggatatct atgaaaagtt gatcaagggt tatacagaaa agcaatgggg
    16981 acgctcagcg atagaacttc ctccatttat cataaaacgc cttccagttc gtttaacctt
    17041 tgataataac tattttaatg accgttacca agggattcct attggtggtt acaatgtcat
    17101 catcgaaaat atgctgaaag atgtagaagt tgaacttgga gtagactttt ttgctcatcg
    17161 tgaagagttg gaagcatctg ctaacaaagt tgtcttcaca ggaatgatcg accaatattt
    17221 tgactacaag cacggagagt tagaataccg tagccttcgt tttgagcatg agattttaga
    17281 cgaggaaaat tatcaaggga atgctgtagt gaactataca gagcgtgaga tcccttatac
    17341 tcgtatcatc gaacacaaac attttgaata tggaatgcag ccaaagacag ttatcacgca
    17401 tgaatatcca gctgactgga agcgtgggga cgagccctac tatcctatta acgatgagaa
    17461 aaataatgct atgtttgcta aataccaaga agaagcagcg cagaatgata aagttatctt
    17521 ttgtgggcgt ttagcagatt ataagtatta cgatatgcat gtggtgattg aacgggcgct
    17581 tgaggttgtg gagaaagaat ttagtaattg aaaaacaacg aagaaaggtt gcttattatg
    17641 aaaggtatta ttctagcagg tggttcggga actcgcttgt atcctttgac tcgagccgca
    17701 tcaaaacaac ttatgccggt ttatgataaa ccgatgattt actacccact ttcaacatta
    17761 atgttggctg ggattaggga tattttgatt atctcaactc ctcaagattt gcctcgtttt
    17821 aaagagcttc ttcaagatgg ttccgagttt ggtattaaac tttcttatgc tgagcaacca
    17881 agtccagatg gtttggcaca agcctttatc attggggaag agtttatttc tgatgatagc
    17941 gttgcgctaa tcttaggtga taatatctac catggttctg ggctttccaa gatgctacaa
    18001 aaggcagcga gtaaggagtc gggagcaact gtttttggct accatgtcaa ggatccagag
    18061 cgctttggtg tggttgagtt tgatcaggat atgaaggcta tttctattga agaaaagcca
    18121 gagcaacctc gttcaaacta tgcagttaca ggtctctatt tctatgataa tgatgtagta
    18181 gagattgcca agagtattaa accaagtcct cgtggtgaac tggaaattac agatgtaaac
    18241 aaagcttacc tagatcgtgg tgatttgtct gttgagctta tgggacgtgg ctttgcttgg
    18301 ctggatactg gaactcatga aagtttacta gaggcttcac agtacatcga aacagtccaa
    18361 cggatgcaaa atgttcaggt agcaaactta gaagaaattg cctatcgcat gggttatatc
    18421 agtcgtgaag atgtattgac cttagctcaa ccacttaaga aaaatgaata cggacagtat
    18481 ctgctccgtt tgattggaga agcatagatg acagataatt ttttcggtaa gacgcttgcg
    18541 gcacgcaagg ttgaagctat tccaggcatg ttggagtttg atatccccgt tcatggagat
    18601 aatcgtggct ggtttaaaga aaatttccaa aaggaaaaaa tgcttccact tggatttcca
    18661 gagtctttct ttgcagaagg aaaattgcaa aacaatgtat ccttctcacg taaaaatgtc
    18721 cttcgagggc tccacgcaga gccttgggat aagtacatct ctgtagcaga tggagggaaa
    18781 gttctgggtt cttgggttga tctacgcgag ggtgaaacct ttgggaatac ctatcagaca
    18841 gtaattgatg caagcaaggg aatctttgtt cctcgaggcg tagctaatgg cttccaagtt
    18901 ctatcagata cagtgtcata tagctatctg gtcaatgatt actgggctct cgagctcaaa
    18961 cccaagtatg cctttgtgaa ctacgctgat ccaagccttg gtattgaatg ggaaaatatt
    19021 gcagaagcag aggtttcaga agcagataaa catcatcccc tacttaagga tgtaaaacct
    19081 ttgaaaaaag aagatttgta aaaaggaaag aatatgactg aatacaaaaa tattatcgtg
    19141 acaggtggag ctggctttat cggttctaac tttgtccatt atgtttacga gaactttcca
    19201 ggtgttcacg tgacagtcct agataagttg acttatgctg gaaatcgcgc gaatattgag
    19261 gaaattttag gtaatcgtgt tgagttagtt gttggtgaca ttgctgatgc ggagttggta
    19321 gacaagttgg ctgctcaagc agatgctatc gttcattatg cagcggaaag ccacaatgat
    19381 aattcgctca atgatccatc gccatttatt catactaact tcatcggaac ctatactctt
    19441 ttagaagctg ctcgtaagta tgatattcgc ttccaccatg tatcgacaga tgaagtttat
    19501 ggggatctcc ctttacgcga agatttgcca ggtcatggtg aaggaccagg tgagaaattt
    19561 actgctgaaa caaaatacaa cccaagctct ccgtactcat caaccaaggc agcctcagat
    19621 ttgattgtca aagcctgggt gcgttctttt ggagtcaagg caacgatttc caactgttca
    19681 aataactacg gtccttatca acatatcgaa aaattcatcc cacgtcagat tactaacatc
    19741 ctaagtggaa ttaagccaaa actttacggt gaaggtaaga atgttcgtga ctggattcat
    19801 accaatgacc attcttcagg agtttggaca atcttgacaa aagggcaaat cggtgaaacc
    19861 tacttgattg gggctgatgg tgagaagaac aataaggaag ttttggaact tatccttaag
    19921 gaaatgggac aagctacgga tgcctatgat catgtgactg accgtgcagg acatgacctt
    19981 cgctatgcga ttgatgccag caagctccgt gatgagttgg ggtggaaacc tgaatttacc
    20041 aactttgaag ctgggctcaa ggcaacaatc aagtggtata cagataacca agaatggtgg
    20101 aaagcagaaa aagaagctgt tgaagccaat tatgctaaga ctcaggagat tattacagta
    20161 taaaaagcag gaaatagctg ctttttattg ctatattggg aagagttaca tattagaaag
    20221 gtctagagat gattttaatt acaggggcaa atggccaatt aggaacggaa cttcgctatt
    20281 tattggatga acgtaatgaa gaatacgtgg cagtagatgt ggctgagatg gacattacca
    20341 atgaagaaat ggttgagaaa gtttttgaag aggtgaaacc gactttagtc taccattgtg
    20401 cagcctacac cgctgttgat gcagcagagg atgaaggaaa agagttggac ttcgccatca
    20461 atgtgacggg gacaaaaaat gtcgcaaaag catctgaaaa gcatggtgca actctagttt
    20521 atatttctac ggactatgtc tttgacggta agaaaccagt tggacaagag tgggaagttg
    20581 atgaccgacc agatccacag acagaatatg gacgcactaa gcgtatgggg gaagagttag
    20641 ttgagaagca tgtgtctaat ttctatatta tccgtactgc ctgggtattt ggaaattatg
    20701 gcaaaaactt cgtttttacc atgcaaaatc ttgcgaaaac tcataagact ttaacagttg
    20761 taaatgacca gtacggtcgt ccgacttgga ctcgtacctt ggctgagttc atgacctacc
    20821 tagctgaaaa tcgtaaggaa tttggttatt atcatttgtc aaatgatgcg acagaagaca
    20881 caacatggta tgattttgca gttgaaattt tgaaagatac agatgtcgaa gtcaagccag
    20941 tagattccag tcaatttcca gccaaagcta aacgtccgct aaactcaacg atgagcctgg
    21001 ccaaagccaa agctactgga tttgttattc caacttggca agatgcattg caagaatttt
    21061 acaaacaaga agtgagataa gtagtagaat gattttctag tctaataaaa gaggcagaga
    21121 atgaactcca aaggagctta agatgtacga ttatcttgtt gttggtgcag tctttgccca
    21181 tgaagcagtc ttaaaaggaa aaaaagtaaa agttattgaa aaatgaaatc atatcgcggg
    21241 taatatctat actcgtgaag aggaaggaat tcaagttcat caatatggtg ctcatatctt
    21301 ccatacttct gataaggaga tctgggatta tgtaaatcag tttgcagagt ttaaccgtta
    21361 taccaattct cctgttgcaa actataaggg agagatttat aacttacctt ttaatatgaa
    21421 taccttcaat aaactctggg gagttgtgac gccagcagaa gcacaagcta agattgatga
    21481 acaacgtgct attttaaatg gtaaaactcc tgaaaatttg gaagaacagg cgatttctct
    21541 tgtaggtaca gacatctacg aaaaattaat caaagactat acagagaaac agtggggcaa
    21601 accaactact gaacttccat cctttattat tcgccgttta ccagtacacc tgacctatga
    21661 taacaactat tttaacgata cctatcaagg gattccaatt ggtggttata atgttatcat
    21721 cgaaaatatg ctgaaggatg tagaagtaga acttggagtg aacttttttg ccaatcgtca
    21781 agaattagag gcttctgctg aaaaggttgt ctttacaggg atgattgacc aatactttga
    21841 ttataaacat ggtgagttag aatactgtag tcttcgtttt gatcatgaag ttctagatga
    21901 ggaaaactat caaggaaacg cagttgtgaa ctatacggat gcagaaaccc catatactcg
    21961 cattattgaa cacaaacatt ttgagtttgg gagtcaagca aagactatca ttactaatag
    22021 aacattctaa aacatgggaa aaaggtgatg agccttatta tccagttaat aatgatcgta
    22081 ataatcattt gtataaatca tataaaaaac ttgctgatga gcaagggaat gttatctttg
    22141 gtggccgctt aggacactat cgttattacg atatgcacca agtaattgga gcagctttgc
    22201 agtgcgtgag aaatgagtta gattcatact caatgaaaat caaagagcaa actaggaagc
    22261 tagccgtagg ttgctcaaaa cactgttttg aggttgcaga tggaagctga cgcggtttga
    22321 agagattttc gaagagtata aacaagtaaa actgactacc agttattatt tagaaatagt
    22381 attaaaaatt ccttgactat gtgatatagt tgagggattt ttaaatgata ttcatatttt
    22441 ttgcaaagat gttgtttgaa aaataatttt caaaaattct gaaaattctg ttgacaactt
    22501 tctgaaaaga gtctataatg gagagaaagt tttaaaggag aaaatgatga aaagttcaaa
    22561 actatttgcc cttgcgggcg tgacattatt ggcggcgact actttagctg catgctctgg
    22621 atcaggttca agcactaaag gtgagaagac attctcatac atttatgaga cagaccctga
    22681 taacctcaac tatttg
//
