LOCUS       CR931684               23047 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 1039/41 (serotype 23b).
ACCESSION   CR931684
VERSION     CR931684.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23047)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 23047)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..23047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="1039/41"
                     /db_xref="taxon:1313"
     gene            <1..166
                     /gene="dexB"
                     /locus_tag="SPC23B_0001"
     CDS             <1..166
                     /gene="dexB"
                     /locus_tag="SPC23B_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI33831.1"
                     /db_xref="GOA:Q4K0I6"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K0I6"
                     /translation="DRRFLVVANLSNDKQNFSVDGKVRSVLIENTAAKEVLEKQVLTP
                     WDAFCVEMTD"
     gene            complement(244..1024)
                     /gene="tnp"
                     /locus_tag="SPC23B_0002"
                     /pseudo
     CDS             complement(join(244..564,563..1024))
                     /gene="tnp"
                     /locus_tag="SPC23B_0002"
                     /note="member of homology group 17;
                     member of homology group 17"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS660-like transposase"
     misc_feature    complement(join(280..564,563..976))
                     /gene="tnp"
                     /locus_tag="SPC23B_0002"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 3.8e-13"
                     /pseudo
     gene            complement(1026..2410)
                     /gene="tnp"
                     /locus_tag="SPC23B_0003"
                     /pseudo
     CDS             complement(join(1026..2276,2270..2410))
                     /gene="tnp"
                     /locus_tag="SPC23B_0003"
                     /note="member of homology group 17"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1202 transposase"
     misc_feature    complement(1425..1928)
                     /gene="tnp"
                     /locus_tag="SPC23B_0003"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 6.4e-21"
                     /pseudo
     gene            2578..4032
                     /gene="wzg"
                     /locus_tag="SPC23B_0004"
     CDS             2578..4032
                     /gene="wzg"
                     /locus_tag="SPC23B_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33834.1"
                     /db_xref="GOA:Q4K0I5"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K0I5"
                     /translation="MLIMSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNI
                     LAFRYFNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGL
                     TNRLNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNI
                     DLTVNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKV
                     EAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPI
                     ADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVY
                     NDQDFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKL
                     TSSEALKNYSMIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDL
                     PSYAMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     misc_feature    2578..2703
                     /gene="wzg"
                     /locus_tag="SPC23B_0004"
                     /note="Signal peptide predicted for SPC1186 by SignalP 2.0
                     HMM (Signal peptide probability 0.994) with cleavage site
                     probability 0.458 between residues 42 and 43"
     misc_feature    2791..3138
                     /gene="wzg"
                     /locus_tag="SPC23B_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 8.4e-65"
     misc_feature    3316..3759
                     /gene="wzg"
                     /locus_tag="SPC23B_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 6e-71"
     gene            3986..4765
                     /gene="wzh"
                     /locus_tag="SPC23B_0005"
     CDS             3986..4765
                     /gene="wzh"
                     /locus_tag="SPC23B_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33835.1"
                     /db_xref="GOA:Q4K0I4"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K0I4"
                     /translation="MHLSKLLFRMCWRADEMIDIHSHIVFDVDDGPKSREESKALLTE
                     AYRQGVRTIVSTSHRRKGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPD
                     VLGKLEKNRIPTLNNSRYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALE
                     NNEKRVRELINMGCYTQVNSSHVLKSKLFGEPYKFMKKRAQYFLERDLVHVIASDMHN
                     VDSRPPHMAEAYDLVSQKYGETKAQDLFIDNPRKIVMDQLI"
     misc_feature    4037..4645
                     /gene="wzh"
                     /locus_tag="SPC23B_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 3.2e-38"
     gene            4774..5466
                     /gene="wzd"
                     /locus_tag="SPC23B_0006"
     CDS             4774..5466
                     /gene="wzd"
                     /locus_tag="SPC23B_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33836.1"
                     /db_xref="GOA:Q4K0I3"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K0I3"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSIFIV
                     KPEYTSTTRIYVVNRNQENKPGLTNQDLQAGTYLVKDYHEIILSQDVLEKVATNLKLD
                     IPVKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSIREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGAAAVTVITVLLIELFDTRVKRPEEVEDVLQMP
                     LLGVVPDFNKMK"
     misc_feature    4792..5208
                     /gene="wzd"
                     /locus_tag="SPC23B_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 4e-55"
     gene            5476..6165
                     /gene="wze"
                     /locus_tag="SPC23B_0007"
     CDS             5476..6165
                     /gene="wze"
                     /locus_tag="SPC23B_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33837.1"
                     /db_xref="GOA:Q4K0I2"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K0I2"
                     /translation="MPTLEISQAKLELAKKTEEYYNALCTNPQLSGDDLKVFSISSVK
                     AGEGKTTTSTNIAWAFAHAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPIALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIMQKCDASILVTKAGETKRRELQKAKEQLEQTGKSCLGVVLNKFDTSVDKYGFY
                     GSYGSYRKQKK"
     gene            6180..7541
                     /gene="wchA"
                     /locus_tag="SPC23B_0008"
     CDS             6180..7541
                     /gene="wchA"
                     /locus_tag="SPC23B_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenylphosphate glucosephosphotransferase
                     WchA (initial sugar transferase)"
                     /protein_id="CAI33838.1"
                     /db_xref="GOA:Q4K0I1"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K0I1"
                     /translation="MNEKLAKSSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYMLNLFIKWYWKRAYPNFKGSKKVFLLTATSHVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATREVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLILCG
                     LVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVVYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     misc_feature    6957..7538
                     /gene="wchA"
                     /locus_tag="SPC23B_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 3.7e-157"
     gene            7528..8751
                     /gene="wchF"
                     /locus_tag="SPC23B_0009"
     CDS             7528..8751
                     /gene="wchF"
                     /locus_tag="SPC23B_0009"
                     /note="member of homology group 15"
                     /codon_start=1
                     /transl_table=11
                     /product="putative rhamnosyl transferase WchF"
                     /protein_id="CAI33839.1"
                     /db_xref="GOA:Q4K0I0"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q4K0I0"
                     /translation="MERNSLLLFQTIRRKMKKSVYIIGSKGIPAKYGGFETFVEKLTE
                     YQKDGNIQYYVACMRENSAKSGFTADTFEYNDAICYNIDVPNIGPARAIAYDIAAVNK
                     AIEIAKKNKDEAPIFYILACRIGPFIARLKKKIQAIGGTLFVNPDGHEWLRAKWSLPV
                     RKYWKFSEQLMVKYADLLVCDSKNIEKYIQNDYKQYQPKTTYIAYGTDTSPSILKSED
                     LKIRSWYQEKGLSENGYYLVVGRFVPENNYETMIREFIKSKSKKDFVLITNVEQNKFY
                     DQLLQETGFDKDPRVKFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTK
                     LNLLLDVGFNREVGEDGAIYWRKDNLHKVIEESEQKTIEEIKEIDILSTEQVEKRFTW
                     DFIVNEYENLFLLGK"
     misc_feature    8191..8682
                     /gene="wchF"
                     /locus_tag="SPC23B_0009"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 0.0023"
     gene            9052..10239
                     /gene="wzy"
                     /locus_tag="SPC23B_0010"
     CDS             9052..10239
                     /gene="wzy"
                     /locus_tag="SPC23B_0010"
                     /note="member of homology group 168"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase Wzy"
                     /protein_id="CAI33840.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K0H9"
                     /translation="MTIKINYMFFVCLSFFGIVLSSSQVIVNLGLSSIVQYIAYFLLL
                     LCIFFTLIKNSPDVIANRIAYFSIISFLFIIGINLQNLPFSTKIYLSFSMLIISSLST
                     LPIKLINNINDFRRISYFLLNGILLSTFLGWLFNISLVTVAVEGIGFAYGFNGGLTHK
                     NFYAITILVSYILLFISRKHGTKYQVDSLVLWFDLFLLLVSNTRTIYIILVVFWIVVH
                     SGFIKYIKKNHRPVIITTWLVISLLSIIFFFKHIINNSESYTHRVLGIVNFFKYYESS
                     KFHLFFGDAELAFGDMTKGYTHNIRSVLGWDGTVEMPLLSVMIKNGYVGLIGYGVVLF
                     KFISSVLSMEDRRVKNIGLSILIPLLLSAMVENYIVNISFVFMPVCFCILCSIKNIEF
                     KNN"
     misc_feature    9052..9162
                     /gene="wzy"
                     /locus_tag="SPC23B_0010"
                     /note="Signal peptide predicted for SPC1192 by SignalP 2.0
                     HMM (Signal peptide probability 0.971) with cleavage site
                     probability 0.465 between residues 37 and 38"
     gene            10249..11217
                     /gene="wchV"
                     /locus_tag="SPC23B_0011"
     CDS             10249..11217
                     /gene="wchV"
                     /locus_tag="SPC23B_0011"
                     /note="member of homology group 109"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyl transferase"
                     /protein_id="CAI33841.1"
                     /db_xref="GOA:Q4K0H8"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K0H8"
                     /translation="MKKVSIILPVYNVEQYIKKCLESIQQQTYPNLEVIIVNDGATDK
                     SVEYCEQICKIDSRFSVTHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSYL
                     VSSMENNEADIAICDPAHYYSDRQNNDLNIFYPASSVKVYEKTEALCEMFYQKSFLVS
                     AWAKIYKKELFDDIRFPVGKLFEDSAVMYLLFEKCEKIVYSNAKLYAYVHRDNSITTK
                     KFSDKDLDILDISNTILDHYSGNFRVYKAAVSYKVSACFRILLNSSSEKKYNQIQKDC
                     MTYILRNWRNMLFDKNVRLKNKLALISITLFNPFVKFIYSKVNRWE"
     misc_feature    10261..10773
                     /gene="wchV"
                     /locus_tag="SPC23B_0011"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 3.9e-48"
     gene            11224..12462
                     /gene="wchW"
                     /locus_tag="SPC23B_0012"
     CDS             11224..12462
                     /gene="wchW"
                     /locus_tag="SPC23B_0012"
                     /note="member of homology group 110"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transferase"
                     /protein_id="CAI33842.1"
                     /db_xref="GOA:Q4K0H7"
                     /db_xref="UniProtKB/TrEMBL:Q4K0H7"
                     /translation="MNKYEERYQEDLSKNDFEKLINRRYLSDKELQVEYVKKGTVLPP
                     KVFEMKLSNKLGLQKALHGKGGVVDSKGNYVELSEQKAVGMRNRVYGSYKFNHKNLAI
                     RNEKVIYLNYFINQWGHFLLDVVGRLWYPLLKDTDTKLDYTCYAGTETKLEGNYLEFL
                     ELLGIDKSRLILINRPTQFSEIIIPESSILPGEYYTKEYKMLFNSLVANVKLDNNLES
                     KKIYCSRARLDLAKGKEFGENGIEKVFLKNGYTPVYMETMSLKEQIRTLLSATTIVLT
                     SGSLAHNLLFINNKINVFILNKTYRVNLHQFLINKISEASVSFVDIYRSPLPILYGYG
                     PFLMDITKPLVNFFEDSGFTYDSGTILDKTDYFKFYLKWLWSYKFFLFRLNHIKEGNS
                     EFEKSFKIIRRYYKMGRQYE"
     gene            12455..13843
                     /gene="wzx"
                     /locus_tag="SPC23B_0013"
     CDS             12455..13843
                     /gene="wzx"
                     /locus_tag="SPC23B_0013"
                     /note="member of homology group 111"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase Wzx"
                     /protein_id="CAI33843.1"
                     /db_xref="GOA:Q4K0H6"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K0H6"
                     /translation="MSKYKELAKNTGTFALANFSSKILIFLLVPIYTKVLTTTEYGFY
                     DLVYTTIQLLVPILTLNISEAVMRFLMKEDVSKKSVFSIAILDIFLGSIIFCLLLLVN
                     QIFSLSELISQYSIYIMAIFAFYTLNNFLIQYSKGIDKIGVTAISGVISAAVMLSMNI
                     LLLVVLNWGLLGFFIANICGYVIPCVYIIVKLKLWDLFELKIDRSLQWEMIYYTLPLI
                     LNTLSWWVNNTSDRYIITVIIGIQASAIISVAYKIPQIFSTISAIFIQSWQISAIKIQ
                     EEKEGNTFISKMLLYYNALLLIIASGIILFVKPISNILFGASFYSAWTLVPFLIISSL
                     FNAISGYIGAIMGAKMDTKNIAKSALVGMIANVFLNIVLTFLMGLQGITISTMIASFL
                     IFYMRKDSVEEIAPETYRAIYLSWFLLVVEASLLVYIDFIIGATLVTLINLFLLKDTL
                     KPLCLKLLKGFK"
     misc_feature    12473..13282
                     /gene="wzx"
                     /locus_tag="SPC23B_0013"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.9e-55"
     gene            13840..14994
                     /gene="wchX"
                     /locus_tag="SPC23B_0014"
     CDS             13840..14994
                     /gene="wchX"
                     /locus_tag="SPC23B_0014"
                     /note="member of homology group 53"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol phosphotransferase"
                     /protein_id="CAI33844.1"
                     /db_xref="GOA:Q4K0H5"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="UniProtKB/TrEMBL:Q4K0H5"
                     /translation="MKMNILQYIKILARTIFMLLISTVLLPVRLKNNKILFINFNGKG
                     YGDNPKSICEYLRTTYPDLDLVWLARDNEGFPDGVRVVKYGTFQAFYEQASSKVWVYN
                     VRAFARILKKRGQIYIQTWHGASSFKLIEKQADLPINYVLEAKYDARVTDIMISDSRK
                     QTEEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKELSIHSDDYVILYAPTF
                     RDDGDASYLDINFERLLQCVEHGIKKKCKFLIRLHPNHSHLCNNISFNKNIINATFYS
                     DMQELTLLADVLVTDYSSSIFDFMLLNKPYVRYVNDLEKYAELRGVSDTYYELPDSII
                     KTAEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     misc_feature    13840..13929
                     /gene="wchX"
                     /locus_tag="SPC23B_0014"
                     /note="Signal peptide predicted for SPC1196 by SignalP 2.0
                     HMM (Signal peptide probability 0.640) with cleavage site
                     probability 0.430 between residues 30 and 31"
     misc_feature    14434..14985
                     /gene="wchX"
                     /locus_tag="SPC23B_0014"
                     /note="HMMPfam hit to PF04464,
                     CDP-Glycerol:Poly(glycerophosphate) gl, score 4.3e-73"
     gene            15030..16058
                     /gene="gtp1"
                     /locus_tag="SPC23B_0015"
     CDS             15030..16058
                     /gene="gtp1"
                     /locus_tag="SPC23B_0015"
                     /note="member of homology group 40"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol-2-phosphate dehydrogenase"
                     /protein_id="CAI33845.1"
                     /db_xref="GOA:Q9R921"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="InterPro:IPR016205"
                     /db_xref="UniProtKB/TrEMBL:Q9R921"
                     /translation="MKNNDLKIGSGAIHQISATLSQNSISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     misc_feature    15051..15971
                     /gene="gtp1"
                     /locus_tag="SPC23B_0015"
                     /note="HMMPfam hit to PF01761, 3-dehydroquinate synthase,
                     score 2.9e-70"
     gene            16074..16778
                     /gene="gtp2"
                     /locus_tag="SPC23B_0016"
     CDS             16074..16778
                     /gene="gtp2"
                     /locus_tag="SPC23B_0016"
                     /note="member of homology group 41"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotidyl transferase"
                     /protein_id="CAI33846.1"
                     /db_xref="GOA:O85005"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="UniProtKB/TrEMBL:O85005"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     misc_feature    16077..16775
                     /gene="gtp2"
                     /locus_tag="SPC23B_0016"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 1e-07"
     gene            16775..17626
                     /gene="gtp3"
                     /locus_tag="SPC23B_0017"
     CDS             16775..17626
                     /gene="gtp3"
                     /locus_tag="SPC23B_0017"
                     /note="member of homology group 42"
                     /codon_start=1
                     /transl_table=11
                     /product="putative phosphotransferase"
                     /protein_id="CAI33847.1"
                     /db_xref="GOA:Q4K015"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006357"
                     /db_xref="UniProtKB/TrEMBL:Q4K015"
                     /translation="MNRIRRMKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLF
                     EGTLELLDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYI
                     KENYPKSKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEI
                     LSTKDVPFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRK
                     KLNYSLFETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQDSIKPTYTFKNVK
                     EMWKGIV"
     misc_feature    16850..17536
                     /gene="gtp3"
                     /locus_tag="SPC23B_0017"
                     /note="HMMPfam hit to PF00702, haloacid dehalogenase-like
                     hydrolase, score 5.9e-25"
     gene            17786..18655
                     /gene="rmlA"
                     /locus_tag="SPC23B_0018"
     CDS             17786..18655
                     /gene="rmlA"
                     /locus_tag="SPC23B_0018"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI33848.1"
                     /db_xref="GOA:Q4K0H1"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4K0H1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    17789..18505
                     /gene="rmlA"
                     /locus_tag="SPC23B_0018"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 3.7e-121"
     gene            18656..19249
                     /gene="rmlC"
                     /locus_tag="SPC23B_0019"
     CDS             18656..19249
                     /gene="rmlC"
                     /locus_tag="SPC23B_0019"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI33849.1"
                     /db_xref="GOA:Q9AHA9"
                     /db_xref="HSSP:1NXM"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q9AHA9"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKNHPLLKDVKPLKKEDL"
     misc_feature    18692..19222
                     /gene="rmlC"
                     /locus_tag="SPC23B_0019"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 4.5e-16"
     gene            19262..20311
                     /gene="rmlB"
                     /locus_tag="SPC23B_0020"
     CDS             19262..20311
                     /gene="rmlB"
                     /locus_tag="SPC23B_0020"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI33850.1"
                     /db_xref="GOA:Q4K121"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K121"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    19277..20233
                     /gene="rmlB"
                     /locus_tag="SPC23B_0020"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 7.1e-05"
     misc_feature    19280..20116
                     /gene="rmlB"
                     /locus_tag="SPC23B_0020"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0039"
     misc_feature    19280..20020
                     /gene="rmlB"
                     /locus_tag="SPC23B_0020"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 2.7e-76"
     misc_feature    19283..20095
                     /gene="rmlB"
                     /locus_tag="SPC23B_0020"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.6e-05"
     gene            20377..21228
                     /gene="rmlD"
                     /locus_tag="SPC23B_0021"
     CDS             20377..21228
                     /gene="rmlD"
                     /locus_tag="SPC23B_0021"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI33851.1"
                     /db_xref="GOA:Q4K0G8"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K0G8"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELNFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    20377..21225
                     /gene="rmlD"
                     /locus_tag="SPC23B_0021"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 9.3e-146"
     misc_feature    20380..21021
                     /gene="rmlD"
                     /locus_tag="SPC23B_0021"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00012"
     misc_feature    20380..21009
                     /gene="rmlD"
                     /locus_tag="SPC23B_0021"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.2e-19"
     misc_feature    20383..21111
                     /gene="rmlD"
                     /locus_tag="SPC23B_0021"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2.4e-08"
     gene            order(21304..22257,22274..22489)
                     /gene="tnp"
                     /locus_tag="SPC23B_0022"
                     /pseudo
     CDS             join(21304..22257,22274..22489)
                     /gene="tnp"
                     /locus_tag="SPC23B_0022"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     misc_feature    21310..21753
                     /gene="tnp"
                     /locus_tag="SPC23B_0022"
                     /note="HMMPfam hit to PF03050, Transposase IS66 family,
                     score 8.9e-05"
                     /pseudo
     gene            22688..>23047
                     /gene="aliA"
                     /locus_tag="SPC23B_0023"
     CDS             22688..>23047
                     /gene="aliA"
                     /locus_tag="SPC23B_0023"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI33853.1"
                     /db_xref="GOA:Q4K2T2"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K2T2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    22688..22774
                     /gene="aliA"
                     /locus_tag="SPC23B_0023"
                     /note="Signal peptide predicted for SPC1205 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    22934..23002
                     /gene="aliA"
                     /locus_tag="SPC23B_0023"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
ORIGIN      
        1 cgaccgtcgc ttcctagttg tggctaactt atccaatgat aaacaaaact tttcagtaga
       61 tggaaaagtt agatctgtct tgattgaaaa cactgcggct aaagaagtac ttgaaaaaca
      121 ggtcttgact ccatgggatg ctttctgtgt ggaaatgact gactagaatg agcaagagcc
      181 tgggacaaaa tagttctcga ccacaaaaaa gctagagatt tccaattgtg gaactctagc
      241 tttttaattt tgagtcattc tcttattgta ttttaggagg ttattggcca taagtaccaa
      301 tcccatgtca attctcactt gacgcttgcc cctcagatta catctcttgt aacccaaaca
      361 agcctttatc tgcccaaaga caggttccac atcaatcttg cgttgagcga aaatctgtct
      421 accttgggga gataaaagcg cctgacattc tttagctttc aagttttgat agccttcgtt
      481 catatacagt ccccttttga ggggctgatt caggttcgtc gacgtagtaa accttgattt
      541 cttgttgaaa gtctgtctgt gttttctgat gtttggtatg gtgaaaacga taatactagc
      601 catcaggatg tgtatagcta tcctccttgt cattatagtg ccaattcgct aagtttttag
      661 ctgactgttt atagcctctc ttctgttcct tatcaaacat ggcatattta atcagatggt
      721 ttacctcctt ttcatctaaa cgaaggaggt tctcttcact tccatatcca gcatctgcga
      781 caactgtctt caagtcatgc ggataggttt caaggaatgg cagaagagtc ttggtatctg
      841 tcggatttga aaagacatca tagtgaagaa caaattggtt ttccgtagcg atttgaagat
      901 tataagcagc cttgggttga ctatttttca tatgttcttc cttcatccgc ataaaagtgg
      961 catctggatc ggttttggaa aaactgttag gcccttgaaa tgtctcctga tagttctcat
     1021 atttttcagc acgtactgaa aaatcctcct ttaaactctt cataatcctt tttattttta
     1081 tgaagatatt gtttgaaaga tgtgagtttc cacggatggg tttgtggagg gatatacttg
     1141 cgtctttctt tttttgttct ggttcttgtt caaggttttt cgaatagagt tcatgattta
     1201 gtagctcctt tgtgtgatag attttgtcag cgatattgag gtagatgtca ccatcaaatg
     1261 cttttataac taatgctttt gtctttctga tgaaatagac ttcttttcct tgctcggtag
     1321 ggatatagca acgattttgg aatcggatat ggtgtccact atcgacgact ctctcccgcc
     1381 agtttagcta gaatgagatt tcgttcagag ggcttaggag cctcctcaaa gacagagagt
     1441 tttgtcttgt ttccaaactg ttcattaaag gtttggatat aggaaggcag aaaggtattg
     1501 gcttcttcca aggtatgaat cttgtttcgt tccagttcga taggcaggag agattgtagt
     1561 atctgattga gtctttcgac tctcccttta gcttgaggga tagaggttgt ctcaaggaga
     1621 attcccagtt ggtgacaggc gtatccaaat tgtgtatggg tgtcgtcctc cattttctta
     1681 gagttggagg cttgataggt aaaaacagtt ctcttatctg ttttgatttg aacaggaatg
     1741 ccgtggttgg ctaagatttg ttcgaggaca tgatagtaag cattcaaggt ctcttgtttg
     1801 tcaaaataag cgcctaggat attgccagaa gcatcatcaa tggctaggtg taagttagag
     1861 gtttctgctc caaaccaggc atgagggctg gcatccattt ggatgagttc tccagcaaat
     1921 ttctttctgg gtctactagg atgtaccttt ttagggtctt ccaggaagtt ttcagccgtc
     1981 ggtaagattg gattgtctag gggttgcttg gggttcagtt tagcttgctt tcttactctc
     2041 ctctttgtct ttctatggga cttaggcgac aggatatttt tcttatagag tatttttcta
     2101 acagtagtat cagagagctg aattccttct tcttcagcta gcaattcaca gaaatgacgg
     2161 acatttggtt tatatgtttc ataggagagg tatttcttta ggatacgttc tttgatttca
     2221 tcagggattg catgttttgg ttttcgattt ctgtttccgt gtctgaaggc ttctttcctt
     2281 tctgttgata ggctagtagc agacgattga tttgcctttc agaaagattg agctcgacac
     2341 aggctcgttt ctttgttttc tttccttggg ctatagcttt tatcacaaga tattttttcg
     2401 tttcattcat attcagttgg atcctttaca tatgactatt ctaccaaatg ggacattttt
     2461 acgttcgatt tactaaagac attatcacat tcgaattaca caagatgcag atagtgaaaa
     2521 aaaggtgtag acattaccgt aaaaaagtga tataattgta agatgttcaa tgtataggtg
     2581 ttaatcatga gtagacgttt taaaaaatca ggttcacaga aagtgaagcg aagtgttaat
     2641 atagttttgt tgactattta tttattgtta gtttgttttt tattgttctt aatctttaag
     2701 tacaatatcc ttgcttttag atattttaat ctagtggtaa ctgcgttagt cctactagtt
     2761 gccttggtag ggctactctt gattatctat aaaaaagctg aaaagtttac tatttttctg
     2821 ttggtgttct ctatccttgt cagctctgtg tcgctctttg cagtacagca gtttgttgga
     2881 ctgaccaatc gtttaaatgc gacttctaat tactcagaat attcaatcag tgtcgctgtt
     2941 ttagcagata gtgatatcga aaatgttacg caactgacga gtgtgacagc accgactggg
     3001 actgataatg aaaatattca aaaactacta gctgatatca aatcaagtca gaatatcgat
     3061 ttgacggtca atcaaagttc gtcttacttg gcagcttaca agagtttgat tgcaggagag
     3121 actaaggcca ttgtcttaaa tagtgtcttt gaaaatatca tcgaatcgga gtatccagat
     3181 tacgcatcga agataaaaaa gatttatacc aagggattca ctaaaaaagt agaagctcct
     3241 aagacgtcta agaatcagtc tttcaatatc tatgttagtg gaattgatac ttatggtccg
     3301 attagttcgg tgtcgcgttc agatgtcaat atcctgatga ctgtcaatcg agataccaag
     3361 aaaattctct tgaccacaac gccacgtgat gcttatgtac caatcgcaga tggtgggaat
     3421 aatcaaaaag ataaattgac ccatgcgggc atctatggag ttgattcgtc cattcacacc
     3481 ttagaaaatc tctatggagt ggatatccat tactatgtcc gtttgaactt cacttctttc
     3541 ttgaaattga tcgatttgtt gggtggggta gatgtttata atgaccaaga tttcacatct
     3601 ctacacggga agttccattt cccagttgga aatgtccact tagattctga gcaggctctg
     3661 ggatttgttc gtgagcgcta ttccctagcg gatggtgatc atgaccgcgg gcgcaatcaa
     3721 caaaaggtga ttgcggctat ccttcaaaaa ttaacttcga gcgaagcgct gaaaaattat
     3781 agtatgatca ttgatagctt gcaagattct atccaaacaa acatgcccct tgagaccatg
     3841 ataaacttgg tcaatgctca gttagaaagt ggtggaacgt acaaagtaaa ttcgcaagac
     3901 ttgaagggta ggggacggac ggatcttcct tcctatgcga tgccagatag taacctctat
     3961 atgatggaaa ttaacgacag tagccttgca tctgtcaaaa ctgctattca ggatgtgttg
     4021 gagggcagat gaaatgattg atattcattc gcacattgtc tttgatgtag atgatggtcc
     4081 caagtcaaga gaggaaagta aggctctctt gacagaagcc tacaggcagg gggtgcgaac
     4141 cattgtctct acctctcacc gtcgcaaggg catgtttgaa actccagaag agaagatagc
     4201 agaaaacttt cttcaggttc gggaaatagc taaggaagtc gcgagtgact tggtcattgc
     4261 ttatggggcc gaaatttact acacaccaga tgttttgggt aagctggaaa aaaatcggat
     4321 tccgaccctc aataatagtc gttatgcctt gatagagttt agtatgaaca ccccttatcg
     4381 cgatattcat agtgccttga ttaaaatatt gatgttggga attactccag tcattgccca
     4441 catcgagcgc tatgatgctc ttgaaaataa tgaaaaacgc gttcgagagc tgattaatat
     4501 gggctgttac acgcaagtaa atagttcaca tgtcctcaaa tccaaacttt ttggagaacc
     4561 ttataaattc atgaaaaaaa gagctcagta tttcttggag cgtgatttgg ttcatgtgat
     4621 tgcaagtgat atgcataatg tggacagcag acctccccat atggcagaag catatgacct
     4681 tgtttcccaa aaatacggag aaacgaaggc tcaggacctt tttatagaca atcctcgaaa
     4741 aattgtaatg gatcaactaa tttaggagaa ataatgaaag aacaaaacac gatagaaatc
     4801 gatgtatttc aattacttaa aaccttgtgg aaacacaagc taatcatttt attagtggca
     4861 cttgtgacag gggcgggagc ttttgcatat agcattttta ttgttaagcc agaatataca
     4921 agcaccacgc gtatttacgt agtcaatcgt aatcaagaaa ataagccggg actgacgaat
     4981 caggacttgc aggcaggaac ttatctggta aaagactacc acgaaattat cctttcgcaa
     5041 gatgtattgg aaaaggtagc gacaaatttg aaattggata ttccagtaaa aacgttaact
     5101 agcaaagtgc aagtgactgt accagccgac actcgtatcg tctcaatctc tgtcaaggat
     5161 aaacaaccag aggaagccag tcgcattgct aattctatac gagaagttgc tgcagaaaag
     5221 atcatcgctg taacgcgagt atctgatgta acgacgcttg aagaagcgcg accagctacg
     5281 actccctctt ctccaaatgt tcgacgcaac accttagttg gttttcttgg agccgccgcc
     5341 gtaacagtaa ttactgttct tttgattgag ttgttcgata cccgtgtaaa acgtcctgaa
     5401 gaagttgaag atgtactgca aatgccactt ctaggagtcg ttccagattt taataaaatg
     5461 aaataggagg aagttatgcc aacgttagaa atctcacagg cgaaattaga acttgcgaaa
     5521 aagacagagg aatattataa tgctttgtgc acgaacccac agttaagtgg agatgatttg
     5581 aaagtatttt ctatcagttc tgtgaaagca ggagaaggaa aaacaacgac ttccaccaat
     5641 atcgcttggg cttttgcgca tgcaggttac aaaacgctgc tgattgatgc agacatgcgt
     5701 aactccgtta tgtcaggtgt ctttaaatca agggaaagga ttactgggct aacagaattt
     5761 ctatcaggga caacagacct gtcacagggg ctttgcgata ccaatgttga gaatctcttt
     5821 gtgattcagg ctggctctgt gtcaccaaat ccgatagccc ttcttcaaag taagaatttc
     5881 agtacaatgc ttggaacctt gcgtaaatat tttgactata tcgtcgtaga cactgctcct
     5941 atcggtatcg tgattgatgc ggctatcatt atgcagaaat gtgatgcttc tattttagtg
     6001 acgaaggcag gtgaaacaaa acgacgggaa cttcaaaaag cgaaagaaca gttggaacaa
     6061 actgggaagt cgtgtttagg agttgtgttg aataaattcg atacttcagt agacaaatac
     6121 ggtttttatg ggagttatgg gagttacagg aaacagaaaa aataggttga gggatagaga
     6181 tgaatgaaaa actagcaaag tcttcagtag ctatagtcca gagttttctt gttattttat
     6241 tgacttatct acttagcgct gtgagagaaa cagagattgt ttcaacaaca gctattgtac
     6301 tttatatcct ccactatttt gtcttttata tcagtgatta tggacggaat ttctttaaaa
     6361 ggagatattt gattgaactt gtccagacat tgaaatatat cctattcttt gcgctagcga
     6421 ttagtatttc taattttttc ttagaggatc gatttagtat ttccagacga ggcatgattt
     6481 acttcctcct attacatgtt ttcttagtct atatgctaaa cctatttatc aagtggtatt
     6541 ggaagcgggc ttatcccaac tttaaaggaa gtaagaaggt tttcctactt acagcaactt
     6601 ctcatgtcga aaaggtactg gatagactaa tagaatcaga tgatgttgtt ggggagttgg
     6661 tagccgtcag tgttttagat aaaccagatt ttcagcatga tgatttaaag gttgtagcag
     6721 agggggagat cgtaaacttt gcgactcgtg aggtggtcga tgaagtcttt atcaatcttc
     6781 caagtgaaaa atacaatatt ggagagcttg tctctcagtt tgaaacgatg ggaattgatg
     6841 taacagtcaa tctaaatgct ttcgattggg cacgtaacaa gcaaatttgt gagatggcag
     6901 gactaaatgt tgtgactttt tctacaacat tttataagac tagccatgtg attgctaagc
     6961 gggttattga tattatcggt tccctggtag gtttgatact atgtggtcta gtcagtattg
     7021 tgctggttcc tttgattcga aaggatgggg gctctgctat ttttgctcag acgcgtatag
     7081 gaaaaaatgg ccgccatttc actttttaca agtttcgctc tatgtgtgta gatgctgagg
     7141 ataaaaagag agaactcatg gaacaaaata ccatgcaggg tggaatgttt aaggtggacg
     7201 atgatcctcg tatcacgaaa attggtcatt ttatacggaa gacgagcttg gacgagctac
     7261 cacagtttta taatgttcta aagggagata tgagtttggt aggtacacga ccaccaacag
     7321 tggacgagta tgaacactat accccagaac aaaaacgtcg gctaagtttt aaacctggta
     7381 taacaggctt atggcaggtc agtggacgaa gtgaaatcaa aaatttcgat gaagttgtca
     7441 aattagatgt ggtctatatt gatggttgga caatctggaa agatattgaa attttattga
     7501 agacagttaa agttgtattg atgaaggatg gagcgaaata gtttgctttt gtttcagact
     7561 attaggagaa aaatgaagaa gtcagtttat atcattggtt caaaagggat tcccgctaag
     7621 tatgggggct ttgaaacctt tgttgagaaa ttaacagaat atcaaaaaga tggtaacatc
     7681 caatactatg ttgcctgcat gcgcgaaaat tctgcaaaat caggatttac agcagataca
     7741 tttgagtaca atgatgctat ttgttacaac attgatgtgc ctaatattgg tcctgctaga
     7801 gccattgctt atgatattgc tgctgtgaat aaagcgattg aaatagctaa gaaaaacaaa
     7861 gatgaagctc ctatttttta cattctagct tgtcgtatcg ggccttttat agctagactt
     7921 aagaaaaaga ttcaagctat cggaggtact ctgtttgtca atccagatgg acatgagtgg
     7981 cttcgggcta aatggagcct gccggttcga aagtattgga aattttcgga acagttgatg
     8041 gtcaaatatg cagatttatt ggtctgtgat agcaaaaata ttgaaaaata tatccagaat
     8101 gactataagc aatatcaacc aaagacgact tatattgctt acgggacgga tacaagtccg
     8161 tctatcctga aatccgaaga tctaaaaatt cgtagttggt atcaggaaaa aggacttagc
     8221 gaaaatggct attatctagt ggtgggacga ttcgtccctg aaaacaacta cgaaaccatg
     8281 attcgtgaat ttatcaaatc taagtccaag aaggactttg tcctcatcac aaatgtggag
     8341 cagaataaat tttacgacca gttgttacag gagactggtt ttgacaaaga tcctagggtt
     8401 aaatttgtag gtactgtcta tgaccaagaa ttgcttaagt acattcgtga aaatgctttt
     8461 gcctatttcc atgggcatga ggttggaggg accaaccctt ctctactaga agctctagca
     8521 tccacaaaac tgaatttgtt gctagatgtt ggttttaacc gtgaggttgg tgaagacggg
     8581 gctatttatt ggagaaaaga taatcttcat aaggttattg aagagagtga acaaaaaaca
     8641 atagaagaaa taaaagaaat agatattcta tctacagagc aggtagaaaa aagatttact
     8701 tgggatttta ttgttaatga atatgaaaat ttatttttac tagggaaata attatctaag
     8761 ttacaaggat tttatttgag gaagctttga tggaagttca tcactttctt agacaattat
     8821 ctaaataact tatgttattc atgaagtttt taaaatgata gatattctcc ctttttgcaa
     8881 agatactaaa attatagaga ggaaatatgc ccagtagttg atagtgtttt tgggtagggt
     8941 taaacgacat agttttaaga caaactggtg gagatttaag aaataagtag ttcttattaa
     9001 atcaaaaacg tgttcttatt ctatattgtc atttagtcaa aggtatcaag tatgactatt
     9061 aaaattaatt atatgttttt tgtttgtctc tcttttttcg gtatagtttt aagtagttca
     9121 caggtaatag tgaatctggg tttgtccagt atagttcagt atatagctta ttttttattg
     9181 ttgctatgta tattttttac cttaattaaa aatagtccgg atgtaatcgc taatagaatt
     9241 gcttattttt ctattatttc atttttgttt atcataggga ttaatttaca aaatcttcct
     9301 ttctcaacaa agatttattt atcgttttcc atgcttatta tttctagtct atcgacttta
     9361 ccgattaaat taataaataa tataaatgat tttagaagaa tatcctattt tttattaaat
     9421 ggcatcctat tatcaacatt tttaggttgg ctatttaata tttcattagt aactgttgct
     9481 gttgagggga ttggttttgc atatggattt aatggtgggt tgacgcataa gaatttttat
     9541 gcaattacaa ttttagtttc ctatatccta ttgtttatta gtagaaaaca tggtacgaag
     9601 taccaagttg atagcttagt attatggttt gatctttttt tacttttagt atctaacaca
     9661 cggacaatat atataatatt agttgttttt tggatcgttg ttcatagcgg atttattaaa
     9721 tatataaaga aaaatcacag accagtaatt ataacgacat ggttagtaat ttctttatta
     9781 tctataatat tttttttcaa acacattata aataatagtg aatcctatac tcatcgtgtt
     9841 ttgggtattg ttaatttttt taaatactac gaatctagca aatttcattt attttttggt
     9901 gatgctgagt tagcctttgg tgatatgacg aaaggttata ctcacaatat aagaagtgtt
     9961 ttaggttggg atggaactgt ggaaatgccg ttgctaagtg ttatgataaa aaatggttat
    10021 gtcggcttaa tagggtatgg agtagtctta tttaaattta tatcctctgt attatctatg
    10081 gaagatagaa gagtaaaaaa tattggctta tccattctaa tacctctact tctatcagca
    10141 atggttgaaa attatatcgt taatattagc tttgtattca tgccggtctg tttttgtatt
    10201 ttatgctcaa taaaaaatat agaatttaaa aataattgaa agtgatttat gaaaaaagta
    10261 agtattattc tacctgtcta caatgttgaa cagtatataa aaaaatgctt agaatcaatt
    10321 caacaacaaa cttatccaaa tttggaagta atcattgtta atgacggagc aaccgataaa
    10381 agcgttgaat actgtgagca aatttgtaag atagattcta ggttttctgt cactcacaaa
    10441 gaaaatggtg gactttccga tgcaagaaat gtcggtatag ataaagccaa gggagattac
    10501 ctcatttttg ttgacagtga tgattttgtc tctcaagata tggtatctta tttagtatct
    10561 agtatggaga acaatgaggc agacattgct atttgcgatc ctgctcatta ttatagtgac
    10621 cgtcaaaaca atgatcttaa tattttttat ccggcatcaa gcgttaaggt ttacgaaaaa
    10681 acggaagctc tatgtgagat gttttatcaa aaatcttttt tggtatctgc ttgggctaag
    10741 atatataaaa aggaactatt tgatgatatc agattccctg ttgggaagtt atttgaagat
    10801 agtgctgtta tgtatctgct ttttgaaaaa tgtgaaaaga tagtatattc taatgcgaaa
    10861 ttatatgcct atgtgcatag agacaatagt attacaacaa agaagttttc agataaagat
    10921 ttagatattt tagacatttc aaatactatt cttgatcact atagtgggaa ctttagagtt
    10981 tataaagcgg cagtttccta taaagtttcg gcatgtttta gaattttgtt gaactcatct
    11041 tcagaaaaaa aatataatca aatacaaaaa gattgtatga catatatttt acgaaattgg
    11101 agaaatatgt tatttgataa aaatgtccga ttaaagaaca agcttgcctt gatttctata
    11161 actcttttca atccttttgt taaatttatc tatagcaaag taaacagatg ggaataatag
    11221 caaatgaaca aatatgaaga aagatatcag gaagatttat ctaagaatga ttttgagaaa
    11281 ctaatcaata gaagatacct atcggataaa gaactacaag ttgaatatgt aaaaaaagga
    11341 acagtgttac ctcccaaggt ctttgaaatg aaactatcaa ataaacttgg tctacaaaaa
    11401 gctttgcatg ggaaaggtgg tgttgtagat tcaaagggga attatgttga actttctgaa
    11461 caaaaagcag ttgggatgag aaatcgagtc tatggatctt acaaatttaa ccataaaaat
    11521 ttggctatca gaaatgaaaa agttatttac ctaaactatt tcataaatca gtggggacat
    11581 tttttactag atgttgtggg gagattatgg tatccattac taaaagatac tgatactaaa
    11641 ctggattaca catgttatgc tggtacagaa acgaaacttg aaggaaacta tttagagttt
    11701 ttagaactcc tcggtataga taaatcacgc ttaattttga taaatcgccc aactcaattc
    11761 tcagagataa ttatacctga aagttcaatt ctgccaggtg aatattatac aaaagaatat
    11821 aaaatgcttt ttaattcttt agtagcaaat gttaaattag ataacaattt agaatcaaaa
    11881 aaaatttatt gttcacgagc taggctagat ttagcaaaag gtaaagagtt cggtgagaat
    11941 ggtattgaaa aggtcttctt aaaaaacggt tatactccag tttatatgga aacaatgtct
    12001 ttgaaagaac aaataagaac gctattatca gctacaacaa tagtattaac tagcggttcg
    12061 ttggctcata atttattgtt tataaacaat aaaattaatg tttttatttt aaataaaact
    12121 tatagagtaa atcttcacca atttttaata aataaaatct cagaagctag tgtgagcttt
    12181 gtggatattt atcgttcccc gttacctatt ttatatggat atggtccatt tttaatggat
    12241 attactaaac ctttagtgaa tttttttgag gacagtggct tcacctatga ttcaggaacc
    12301 attttagata aaactgatta ttttaaattt tatttaaaat ggttatggag ttataaattc
    12361 tttctattta gactgaatca cattaaagaa ggaaacagtg aatttgagaa gagttttaaa
    12421 ataattagaa gatattataa aatgggacga cagtatgagt aaatataagg aattagcaaa
    12481 aaatacaggt acttttgctt tagctaattt ttcatcaaaa atattaattt ttttgttagt
    12541 acctatatat acaaaagttc taacaacgac agagtatggt ttttatgatt tggtttatac
    12601 aacaattcag ctccttgtac caatcctgac attgaatata tctgaagcag ttatgagatt
    12661 tttaatgaaa gaagatgttt caaaaaaatc agttttttcg attgcaatac ttgatatatt
    12721 tttagggtct attatttttt gtttgttact actggtcaat caaatatttt ctttatcgga
    12781 gttaatttct caatatagca tatatatcat ggcgattttt gctttttata cacttaataa
    12841 ttttttgata caatactcta aagggattga taaaataggt gtaacggcta tctctggagt
    12901 cataagtgca gcagttatgc tttcgatgaa tattttattg ttagtggtat taaattgggg
    12961 actactaggt ttttttatcg caaatatttg tgggtatgtc attccttgtg tatatataat
    13021 agtaaaacta aaattatggg atttatttga acttaaaatt gatagatcgt tacagtggga
    13081 aatgatatat tatactttac ctttgatttt aaatacttta agttggtggg ttaataacac
    13141 ttcagatagg tatattataa cagtaattat aggtatacaa gctagtgcga ttatttcagt
    13201 tgcttataag attccacaaa ttttttccac aattagcgct atattcattc aatcgtggca
    13261 aatatctgca ataaaaattc aggaagaaaa agaaggtaac acctttatat caaaaatgct
    13321 tttatattat aatgcactct tgctgattat agcgagcggt atcattctat ttgtaaaacc
    13381 aatctctaat atactcttcg gagcttcatt ttattcagcg tggacgcttg taccgttttt
    13441 aattattagc agtttgttta atgcgatttc gggttatata ggagcgataa tgggcgctaa
    13501 aatggatact aaaaatattg ctaaatctgc tttggttgga atgatagcta atgttttttt
    13561 aaatattgta ttaacatttt taatgggact acaggggatt acaatctcaa ctatgatagc
    13621 tagttttctt attttttata tgagaaaaga tagtgttgaa gaaattgctc cagaaacata
    13681 tagagctatt tatctttcgt ggtttttgtt agtggttgag gctagtcttt tggtttatat
    13741 agattttatt attggggcta cattagttac attaatcaat ttatttttat taaaggatac
    13801 tcttaaacca ttatgtttaa aattattaaa aggatttaaa tgaaaatgaa tattctacaa
    13861 tacattaaaa ttttggctag aactattttt atgctattga taagtacagt gttattacct
    13921 gtcaggttaa aaaataataa gattctattt attaatttca atgggaaggg ttatggtgat
    13981 aatcctaaaa gtatttgtga gtatcttaga actacttacc cagatttaga tttggtttgg
    14041 cttgcaagag ataacgaagg ttttccagat ggggttaggg ttgttaaata tgggactttc
    14101 caagcttttt atgagcaagc gagttcgaag gtttgggtat ataatgtaag agcttttgca
    14161 agaatactaa aaaaacgagg acagatttat attcaaactt ggcatggtgc ttctagtttt
    14221 aagttgatag aaaaacaagc tgatttacca ataaattatg ttttagaagc taagtatgat
    14281 gcaagagtca cagatataat gatttcagat agcagaaaac aaactgaaga atttcaaaag
    14341 tatttttggt attcaggaga aatttttgag gtggggatgc cgagaaatga tgccttgttt
    14401 cactataagg aagactacga caagttaaat aatatcagaa aagaactaag cattcattca
    14461 gatgattatg ttattttata tgcccctact ttcagagatg atggggatgc atcttattta
    14521 gatataaatt ttgaacggct tttgcaatgt gttgaacacg gaattaaaaa gaaatgtaaa
    14581 ttcttaatta ggttacaccc taatcactcc catttgtgta ataatatttc atttaataag
    14641 aatataatca atgctacgtt ttattcagat atgcaagagc ttactttgtt ggcagatgtt
    14701 ttagtcacag attattcttc ctcgatattt gattttatgc ttttaaacaa gccttatgtc
    14761 agatatgtga atgatttaga aaaatatgct gagcttaggg gggtatcaga tacatattac
    14821 gaattgccgg attcgattat taaaactgct gaagaattgt atgacttact gcctaaaaaa
    14881 atagaaaatt ttgattatga ttctataaaa aaatatagaa atgaaatact gtgtccaatc
    14941 tttaatggaa ccgctagtga aaatgtagga aggagaataa ttcaagagtt gtgaagtaaa
    15001 acattgggtt atttttaagg taacgagatt tgaaaaataa tgatttaaag ataggaagtg
    15061 gagctattca tcaaatttcc gctacacttt ctcaaaatag tatttcggga aagattttat
    15121 attgtgctga tccagttgtc gatgacttgt acggttcgat agtacgttca caaatagagg
    15181 aaattggtcg ggtaaaggaa gaaagttgca attataatac tattgcttat gcgatgaata
    15241 tagcagaacg ggctattgcc acagatattg actgtattgt gggaatggga ggaggtcgtg
    15301 ttttagatgt ctgcaagtat gcatctttta tttcgaaacg tccttaccta tcgattccga
    15361 caacagcagc aaatgatggc attgcttccc cagttgctgt tttgaaaagg caggatgata
    15421 gaccaaaaag cttaggggcg gctatcccct caatgacact aattgatatt gatgttattg
    15481 catcaggacc tatacaaaat ataaaagctg gtatcggtga tacaatatcc aattacactg
    15541 cattgaaaga ttgggagttg gcagttgagc gagggaaaga tgagatgcat ggttttgcat
    15601 atctaatgtc gcaaaattct ttagatgctt taatgaaaac gaagtataat tctattaccc
    15661 ctgattttat tgaagttttg gtaaactctt tagttttatc aggcattgca atggattttg
    15721 cgggaagtag tagacctgtc agtgggtcag agcacttatt tagtcatgca ttagattact
    15781 atggttctac aaggaatctt catggaattc aggttgcatt aggtacagtc gcagttttga
    15841 aattaattga aaattctgtt gatactgtag tggattactt gcaaagattt gaggttcata
    15901 ttaacccgaa acttttgggg atagatgaag agttgtttat ttattgtatg caacatgcta
    15961 caaaaatgag aagtaatcgc tatacctatc tgcatgaagt tgatcttagc acagatagat
    16021 tgaaacaaat atataaggaa ctcataagcg agttgtagag aagagaggaa aaaatgaaag
    16081 cacttatttt agcagcaggg ttaggaacac gtctagctcc aattaccaat gaggtaccaa
    16141 aatctttggt accagtcaat ggtaagccaa ttttgatgaa acaaattgaa aatttatatc
    16201 aaaataatat tacagatatt acgattattg ctggatataa gtcatctgta ttaacagatg
    16261 cagttactga aaagtatcca gaaattaata ttattgataa tgttgatttt aaaacgacta
    16321 ataatatgta ttcagcctat ctaggaaaag ctgcaatggg tgatagtgac ttcttaatga
    16381 tgaatgcaga tgtattttat gatgcttctg ttattaaaag tctgttgctt cataaagctc
    16441 caaatgcaat tgtaactgat ttaggtattt atattgaaga gtctatgaaa gtcgtagaaa
    16501 aaaatggtcg tttagtagaa atttctaaac agatttcacc tgaggaaact ttaggagctt
    16561 ctattgatgt ttataaattc tcttatgaag caggtgctcg attctttgaa aagtgtaagg
    16621 aatttattga agataaacga gaacttcaaa tgtggagtga ggttgctctt aatgcaattc
    16681 tttctgaagt tgaatttgta gcatgtccat tagagggtcg ttggttagaa attgataatc
    16741 atgaagactt agttgctgca gaaaaactat ttgcttgaac cgaatacgga gaatgaaatt
    16801 gacaaataga gttgattatt ttggtgctga tattagtgaa cttcagaata aaaaattatt
    16861 cttatttgat atggatggta ccatttatga agaagatagg ttgtttgagg gtactctcga
    16921 attattagac tatattcata atattggcgg tgagtatatt tttattacaa acaattcatc
    16981 taagtctgtt gttgactatg ttgaaaaagt taacagatta ggtattaaag ctgaacgaga
    17041 taattttttt acctctgctc aagccacaat tgtttatatt aaagaaaatt atcctaaatc
    17101 taaagtttat tgccaaggaa caaaatcttt gataaaagaa ctatctgacg caggaattga
    17161 tgtaactgag caagttagtg ctgatataga tgttgttctt gttggttttg atacagaatt
    17221 aaccagtgat aaaattcgca atacctgcga gattctatca acaaaggacg tacctttcat
    17281 agctactaac cctgatattc gctgcccagt atcgtttgga ttcatcccgg attgtggttc
    17341 tatttgtgat atgattagta aatcagtcga taggaaacct gtttacatag gtaaacctga
    17401 acctacgatg gttgatattg ttcgaaaaaa attaaattat tctctatttg aaacagttgt
    17461 gattggagat cgcttgtata cggatatcat gactggtata aatgcaggag taacttcagt
    17521 ttgtgtgctg acaggagaag caacggtgaa tgatattcaa caagatagta taaaaccgac
    17581 ttatacattt aaaaacgtga aagaaatgtg gaaaggaatt gtctgatttt ttcattctga
    17641 atagtgaatt catgaatact gtcaaaatac tcgtatgtat ttaaattgat tttattattt
    17701 taataatgga caaattaaaa ttatttttct ccccaaatcg ttcgtgaacg taaagtactc
    17761 atcaacaaag aaaggtaccc cttttatgaa aggtattatt ctagcaggtg gttcgggaac
    17821 tcgcttgtat cctttgactc gcgctgcatc aaaacaactt atgccggttt atgataaacc
    17881 gatgatttac tacccacttt caacattaat gttggctggg attagggata ttttgattat
    17941 ctcaactcct caagatttgc ctcgttttaa agagcttctt caagatggtt ctgagtttgg
    18001 tattaaactt tcttatgctg agcaaccaag tccagatggt ttggcacaag cctttatcat
    18061 tggggaagag tttatcggtg acgatagcgt tgccttgatt ttaggtgaca atatctacca
    18121 tggtcctggt ctgagcacaa tgcttcaaaa agcagccaag aaagagaaag gtgcgactgt
    18181 ttttggctac catgtcaagg atccagaacg ctttggtgtt gtagaatttg atgaaaatat
    18241 gaatgctatc tccatcgaag aaaagccaga ataccctcgt tcaaactatg cagtgacagg
    18301 actctatttc tatgataatg atgtagtaga gattgccaaa agtattaaac caagtcctcg
    18361 tggtgaattg gaaattacag atgtcaacaa ggcttacttg gatcgtggtg atttgtctgt
    18421 tgagctcatg ggacgtggtt ttgcttggtt ggatactggc actcatgaaa gtttactaga
    18481 ggcttcgcag tacatcgaaa cagtccaacg gatgcaaaat gttcaggtag caaacttgga
    18541 agaaattgct taccgtatgg gctatatcag tcgcgaagat gtgttggcct tagcccaacc
    18601 acttaagaaa aatgaatacg gacagtatct actccgtttg attggagaag catagatgac
    18661 agataatttt ttcggtaaga cgcttgcggc acgcaaggtt gaagctattc caggcatgtt
    18721 ggagtttgat atccccgttc atggagataa tcgtggctgg tttaaagaaa atttccaaaa
    18781 ggaaaaaatg cttccacttg gatttccaga gtctttcttt gcagaaggaa aattgcaaaa
    18841 caatgtatcc ttctcacgta aaaatgtcct tcgaggcctc cacgcagagc cttgggataa
    18901 gtacatctct gtagcagatg gagggaaagt tctgggttct tgggttgatc tacgcgaggg
    18961 tgaaaccttt gggaatacct atcagacagt gattgatgcg agtaagggaa tctttgttcc
    19021 tcgaggcgta gctaatggct tccaagtttt atcagataca gtgtcatata gctatctggt
    19081 caatgattac tgggctcttg aactcaaacc caagtatgcc tttgtgaact acgctgatcc
    19141 aagccttggt attgaatggg aaaatattgc agaagcagaa gtttcagaag cagataaaaa
    19201 tcatccacta cttaaggatg taaaaccttt gaaaaaagaa gatttgtaaa aaggaaagaa
    19261 tatgactgaa tacaaaaata ttatcgtgac aggtggagct ggctttatcg gttctaactt
    19321 tgtccattat gtttacgaga actttccagg tgttcacgtg acagtcctag ataagttgac
    19381 ttatgctgga aatcgcgcga atattgagga aattttaggt aatcgtgttg agttagttgt
    19441 tggtgacatt gctgatgcgg agttggtaga caagttggct gctcaagcag atgctatcgt
    19501 tcattatgca gcggaaagcc acaatgataa ttcgctcaat gatccatcgc catttattca
    19561 tactaacttc atcggaacct atactctttt agaagctgct cgtaagtatg atattcgctt
    19621 ccaccatgta tcgacagatg aagtttatgg ggatctccct ttacgcgaag atttgccagg
    19681 tcatggtgaa ggaccaggtg agaaatttac tgctgaaaca aaatacaacc caagctctcc
    19741 gtactcatca accaaggcag cctcagattt gattgtcaaa gcctgggtgc gttcttttgg
    19801 agtcaaggca acgatttcca actgttcaaa taactacggt ccttatcaac atatcgaaaa
    19861 attcatccca cgtcagatta ctaacatcct aagtggaatt aagccaaaac tttacggtga
    19921 aggtaagaat gttcgtgact ggattcatac caatgaccat tcttcaggag tttggacaat
    19981 cttgacaaaa gggcaaatcg gtgaaaccta cttgattggg gctgatggtg agaagaacaa
    20041 taaggaagtt ttggaactta tccttaagga aatgggacaa gctacggatg cctatgatca
    20101 tgtgactgac cgtgcaggac atgaccttcg ctatgcgatt gatgccagca agctccgtga
    20161 tgagttgggg tggaaacctg aatttaccaa ctttgaagct gggctcaagg caacaatcaa
    20221 gtggtataca gataaccaag aatggtggaa agcagaaaaa gaagctgttg aagccaatta
    20281 tgctaagact caggagatta ttacagtata aaaagcagga aatagctgct ttttattgct
    20341 atattgggaa gagttacata ttagaaaggt ctagagatga ttttaattac aggggcaaat
    20401 ggccaattag gaacggaact tcgctattta ttggatgaac gtaatgaaga atacgtggca
    20461 gtagatgtgg ctgagatgga cattaccaat gaagaaatgg ttgaaaaagt ttttgaagag
    20521 gtgaaaccga ctttagtcta ccactgtgca gcctacaccg ctgttgatgc agcagaggat
    20581 gaaggaaaag agttgaactt cgccatcaat gtgacgggga caaaaaatgt cgcaaaagca
    20641 tctgaaaagc atggtgcaac tctagtttat atttctacgg actatgtctt tgacggtaag
    20701 aaaccagttg gacaagagtg ggaagttgat gaccgaccag atccacagac agaatatgga
    20761 cgcactaagc gtatggggga agagttagtt gagaagcatg tgtctaattt ctatattatc
    20821 cgtactgcct gggtatttgg aaattatggc aaaaacttcg tttttaccat gcaaaatctt
    20881 gcgaaaactc ataagacttt aacagttgta aatgaccagt acggtcgtcc gacttggact
    20941 cgtaccttgg ctgagttcat gacctaccta gctgaaaatc gtaaggaatt tggttattat
    21001 catttgtcaa atgatgcgac agaagacaca acatggtatg attttgcagt tgaaattttg
    21061 aaagatacag atgtcgaagt caagccagta gattccagtc aatttccagc caaagctaaa
    21121 cgtccgctaa actcaacgat gagcctggcc aaagccaaag ctactggatt tgttattcca
    21181 acttggcaag atgcattgca agaattttac aaacaagaag tgagataagt agtagaatga
    21241 ttttctagtc taataaaaga ggcagataat gaactccaaa ggagcttaag atgtacgatt
    21301 atcttgttgt tggtgctggt ctctttggcg catagctttg gctcagtttc tattatcgct
    21361 cacatcatcc atcagaagat taatctgaag gtacccaatt atcgccaaga agaagattgg
    21421 gctaggatgg gtttaccaat cacacgtaag gaaatctcta attggcatat caaggcaagt
    21481 caatactatt tagagtccct ttataacctt ttacgagaaa agttgttaga acaacctctt
    21541 cttcatgcgg atgaaacctc ttatcgggtt ctagagagtg atagccatct gacctactat
    21601 tggacctttt tgtctgggaa agctgagaat caagcaatca cgctgtacca tcatgatcag
    21661 cgtcggagtg gtttagtagt acaagaattc ctaggagatt attctggcta tgtgcattgt
    21721 gatatgttgc ggcagtaact taggacttta gtcctctagt tctgcctatg cgatagcagt
    21781 ccaaggttta ggagcaaggc gacgctaagc ttggtaaact gcgaaccgct agaagcttat
    21841 cgtcaactgg aagaagctga acttgttgga tgttgggcac atgtgagaag gaagtttttt
    21901 gaagcgaccc ccaagcaagc agataaatca tccttagaag ctaaaggttt agcttattgt
    21961 gatcagttat tttccctgga aagagactgg gaggctttgc cagctgatga acgactacag
    22021 aaacgtcaag aagagctcca acccctaatg gaagacttct ttgcttagtg ccggcgtcag
    22081 tcagttttag caggttcaaa actaggaagg gcaattgaat acagcctcaa gtatgaagaa
    22141 acctttaaga ctattttgaa agacggacat ctggtccttt ccaataatct agctgaacgc
    22201 gccattaaat cattggttat gggacggagt aaaagagttc agtggactct tttagcctaa
    22261 gctaaatttt aaaaagcgag ggtggttatt ttctcaaagt tttgaaggag ctaaagcaac
    22321 agctattatt atgagtttgt tggaaacagc taaacgtcat caattaaata gcgagaaata
    22381 tctattctat cttctagaat gtcttccaaa cgaggaaact ctcgtaaaca aagaggtttt
    22441 agaggcttat ttaccatgga ctaaagttgt acaagaaaag tgcaaataag aaatctccag
    22501 attaggaact atccgtgagt tctctagtct ggagattttt caatatactt cgttattggg
    22561 cgcttacaat gatattcata ttttttgcaa agatgttgtt tgaaaaataa ttttcaaaaa
    22621 ttctgaaaat tctgttgaca actttctgaa aagagtctat aatggagaga aagttttaaa
    22681 ggagaaaatg atgaaaagtt caaaactatt tgcccttgcg ggcgtgacat tattggcggc
    22741 gactacttta gctgcatgct ctggatcagg ttcaagtact aaaggtgaga agacattctc
    22801 atacatttat gagacagacc ctgataacct caactatttg acaactgcta aggctgcgac
    22861 agcaaatatt accagtaacg tggttgatgg tttgctagaa aatgatcgct acgggaactt
    22921 tgtgccgtct atggctgagg attggtctgt atccaaggat ggattgactt acacttatac
    22981 tatccgtaag gatgcaaaat ggtatacttc tgaaggtgaa gaatacgcgg cagtcaaagc
    23041 tcaagac
//

