LOCUS       CR931689               28466 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain tp 25/38, sp 65/81 (serotype 25a).
ACCESSION   CR931689
VERSION     CR931689.2
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28466)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 28466)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     On Mar 17, 2006 this sequence version replaced CR931689.1.
            NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..28466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="tp 25/38, sp 65/81"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC25A_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC25A_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI33954.2"
                     /db_xref="GOA:Q4JZD8"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4JZD8"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAP
                     WDAFCVELL"
     gene            order(322..1752,1788..2273)
                     /gene="aliB"
                     /locus_tag="SPC25A_0002"
                     /pseudo
     CDS             join(322..1752,1788..2273)
                     /gene="aliB"
                     /locus_tag="SPC25A_0002"
                     /note="member of homology group 169; old_tribe:0162 2"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     misc_feature    join(538..1752,1788..1871)
                     /gene="aliB"
                     /locus_tag="SPC25A_0002"
                     /note="HMMPfam hit to PF00496, Bacterial extracellular
                     solute-binding prot, score 4.5e-36"
                     /pseudo
     gene            complement(order(2417..2998,3052..3740))
                     /gene="tnp"
                     /locus_tag="SPC25A_0003"
                     /pseudo
     CDS             complement(join(2417..2998,3052..3225,3225..3740))
                     /gene="tnp"
                     /locus_tag="SPC25A_0003"
                     /note="member of homology group 13; old_tribe:0015 22"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
     misc_feature    complement(join(2918..2998,3052..3225,3225..3248))
                     /gene="tnp"
                     /locus_tag="SPC25A_0003"
                     /note="HMMPfam hit to PF01610, Transposase, score 2.3e-31"
                     /pseudo
     gene            3778..3999
                     /gene="tnp"
                     /locus_tag="SPC25A_0004"
                     /pseudo
     CDS             3778..3999
                     /gene="tnp"
                     /locus_tag="SPC25A_0004"
                     /note="Lone member of homology group 0248"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase (fragment)"
     gene            4276..5373
                     /gene="glf"
                     /locus_tag="SPC25A_0005"
     CDS             4276..5373
                     /gene="glf"
                     /locus_tag="SPC25A_0005"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6; old_tribe:0006 56"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI33958.2"
                     /db_xref="GOA:Q4K079"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K079"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRNHIGGNIYCEN
                     IEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     TWGTKTPQEVKNKIAEQTAHMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TDLPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKGVEVELGVDFFANRQ
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEVLDKENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQDKTVITREYPADWKRGDEPYYPINDERNNAMFAKYQEEAVQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVRNEFS"
     misc_feature    4711..5313
                     /gene="glf"
                     /locus_tag="SPC25A_0005"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 2.4e-135"
     gene            5691..6371
                     /gene="wzd"
                     /locus_tag="SPC25A_0006"
     CDS             5691..6371
                     /gene="wzd"
                     /locus_tag="SPC25A_0006"
                     /note="member of homology group 2; old_tribe:0002 80"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI33959.2"
                     /db_xref="GOA:Q4JZ56"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ56"
                     /translation="MNNRIVDISLFDLLNVLWLRKWIIVFVSFVFGCISFLYYQFFVP
                     KTYTSDTRIYVVSKGDNKNLSNADLQAGSALTKDYKEIILSDEVLEETISDLKLESTL
                     ESLASKIKISIPAETRIISISVTNTNSDEAARIANGIRKVAALKIKEVTQVTDVTTLQ
                     TARPPQTPSGPHVRKSTTAGLVLGAFLTVFLVVAKEILDDRIKRFEELEKLGIPILGS
                     IPLSKNIK"
     misc_feature    5706..6116
                     /gene="wzd"
                     /locus_tag="SPC25A_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 2.5e-41"
     gene            6378..7067
                     /gene="wze"
                     /locus_tag="SPC25A_0007"
     CDS             6378..7067
                     /gene="wze"
                     /locus_tag="SPC25A_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3; old_tribe:0003 80"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI33960.2"
                     /db_xref="GOA:Q4JZ55"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ55"
                     /translation="MGKLELTRKYYQLYNETKEYFNALQTNIQLSGDGLKVISVTSTV
                     KNEGKSTISVGLSMSLALSGYKVLLLDVDLRNSVMSGMFHSRERITGLTEYLSGKAGM
                     ADSMQETTLDNLYILQAGVVSPNPLSLLRSVKFETLIDSMKKYFDYIIVDTPPIGQVI
                     DAAIIAQQCDGIFLVTEMRKTTRRQIFSSLQQLEQTGVPVLGLVANKAIIKKDSYGYY
                     GKNTASETERY"
     gene            order(7258..7568,7590..7655,7660..7977)
                     /gene="tnp"
                     /locus_tag="SPC25A_0008"
                     /pseudo
     CDS             join(7258..7374,7374..7568,7590..7655,7660..7977)
                     /gene="tnp"
                     /locus_tag="SPC25A_0008"
                     /note="member of homology group 19; old_tribe:0021 15"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
     misc_feature    join(7503..7568,7590..7655,7660..7971)
                     /gene="tnp"
                     /locus_tag="SPC25A_0008"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 2.1e-09"
                     /pseudo
     gene            8198..9649
                     /gene="wzg"
                     /locus_tag="SPC25A_0009"
     CDS             8198..9649
                     /gene="wzg"
                     /locus_tag="SPC25A_0009"
                     /note="member of homology group 0; old_tribe:0000 80"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI33962.2"
                     /db_xref="GOA:Q4K075"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K075"
                     /translation="MRYFMSREKKRGTAVHLKSYINSVLLILYTGIASLFLFQIFRYN
                     ILNFRNLNLLVALLVVLVFILGVSLIVRKKAEKLTMLLLILAVASSSISLLAVQQFIG
                     FTSRLNATSNVSEYAISLVVLKDSEISELEQVSHVMAPTDTDYEAIQSLLADIKEKQG
                     KDLIVDKSKSYLEAYKSLISGDTKVIFLNSIFEHMIESDFPDFRDKIKKIYTKEMTKK
                     VEAPKVSKGQAFTIYFSGIDTYGPINSVSRSDVNILMTVNSETKKILLTTTPRDSYVA
                     IADGGKNRKDKLTHAGIYGIDSSIHTLEHLYGVEINYYVRVNFTSFLKIVDLLNGIDV
                     DDSQEFTIDGNDYPVGNLHLNSKSALGFVRERHSLADGDRDRGRNQQKVLAAIIQKLT
                     SIESLKNYRQIMQGLEDSIQTNLSPTTIMDLANTQLESGGNYKINSQDLKGTGRMDLP
                     SYAMPDSQLYMMEIDENSLSAIKENIQAVLEGR"
     misc_feature    8414..8761
                     /gene="wzg"
                     /locus_tag="SPC25A_0009"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 9.5e-40"
     misc_feature    8939..9376
                     /gene="wzg"
                     /locus_tag="SPC25A_0009"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 6.7e-63"
     gene            9588..10382
                     /gene="wzh"
                     /locus_tag="SPC25A_0010"
     CDS             9588..10382
                     /gene="wzh"
                     /locus_tag="SPC25A_0010"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1; old_tribe:0001 80"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI33963.2"
                     /db_xref="GOA:Q4JZ53"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ53"
                     /translation="MMRIASQLSKKIFRLFWRVGKMIDVHSHIIFDVDDGPKSIEDSR
                     ALLLEAYDQGIRTIVSTSHRRQGMFETPEDKIAENFRAVQKIARDIADDLTILYGAEI
                     YYTQDIINKLEKKTFPTLNGSRYALIEFSSETSYRSIHSALQQLLLSGITPLIAHIER
                     YDALENNKQAVLELIRMGCYTQINSSHLLKKKLFKDDAKIMKKRVHYFLKHDLVHIVA
                     SDMHNLDTRPPYMAEAYEIISKRYGKEKAEEFFIKNPQRILMDQLI"
     misc_feature    9654..10262
                     /gene="wzh"
                     /locus_tag="SPC25A_0010"
                     /note="HMMPfam hit to PF02811, PHP domain, score 3.6e-36"
     gene            10401..10988
                     /gene="wciI"
                     /locus_tag="SPC25A_0011"
     CDS             10401..10988
                     /gene="wciI"
                     /locus_tag="SPC25A_0011"
                     /note="member of homology group 29; old_tribe:0034 8"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33964.2"
                     /db_xref="GOA:Q4K061"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q4K061"
                     /translation="MYKVIKRFIDIALALLGIVLLSPLFLGIIVFIKLESKGPIFFKQ
                     KRIGLHKKEFYILKFRTMRIDTPSAVPTHLLKNPYQWITKVGKVLRRTSLDELPQIWN
                     ILVGHMSLVGPRPALWNQFDLIEERDKYGANDILPGLTGWAQINGRDELSIPVKAKFD
                     GYYVKNCSFVLDCRCVVESFLVVFKRYGHREGGAD"
     misc_feature    10416..10970
                     /gene="wciI"
                     /locus_tag="SPC25A_0011"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 3e-32"
     gene            11001..12131
                     /gene="wcyA"
                     /locus_tag="SPC25A_0012"
     CDS             11001..12131
                     /gene="wcyA"
                     /locus_tag="SPC25A_0012"
                     /note="member of homology group 170; old_tribe:0163 2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33965.2"
                     /db_xref="GOA:Q4K060"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K060"
                     /translation="MGNRKKVFVVANVVKEHILKFHIPTIKEMTKRGWTVDVGASGDE
                     TVPYCHQQYSLPHQRSPFHLGTLKSIWKLRKILKSGGYDIVYCHTPVGGLVGRLASLG
                     LRKQGTRVIYFAHGYHFYKGATFFNWLVYYPIEKLLSLFTDSIILINQEDYHLTKTKF
                     KQVQSYLVSGMGVKQERFSPQSNQVRERYRKELKLPEDATVLIYCAELIKNKNQTFLL
                     HAMKKLVDQGENLYCLLVGIDYTKGEMVECIQSLNLSDRVLLLGWREDIANLYACSDI
                     CVATSIREGFGLNIVEAMFCHVPVVATINRGHASIIQDGQNGLLVQLGNTKQLVEAIY
                     VLMKDTKKKQELVEQASANLEQYHSQKIVNSLLEIIEQTAMK"
     misc_feature    11556..12071
                     /gene="wcyA"
                     /locus_tag="SPC25A_0012"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 3.5e-40"
     gene            12128..13558
                     /gene="wzy"
                     /locus_tag="SPC25A_0013"
     CDS             12128..13558
                     /gene="wzy"
                     /locus_tag="SPC25A_0013"
                     /note="member of homology group 171; old_tribe:0164 2"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI33966.2"
                     /db_xref="UniProtKB/TrEMBL:Q4K059"
                     /translation="MSEGCEKVKIQIDKIYYLFFWLVVSFGYFFMMPTFTEDLEGVVS
                     ASLVQLLLFIIGYVYVSYLNRSFISLYSIFMIVFYLFQNGQVLLYSLGVEYDYFYVLR
                     YDETIVLQSVIFSTQCLIAAFMAGVFSTKKEVSKPLYSYMDQLEREKLITAGKLFWGA
                     FAIFALPFMMMKFVITSTSGYFAMIRFVGSLPTITVLFEKMFIASSVFLVVYLKSEET
                     WSKFLKVVILGWSIMAALTGDRTVGLAGIVTLALIQTLIGNRKKKIKFSQYALLVGAA
                     VVVMYLMSFAFQFRMQQDSKVSGLQTAVVEMIGTLGFSFFPLVLTIRIVPTSINFFRG
                     KSYIAAIITGLIPSNFDFLHLTKTLSEWNAYPTELLDTIYHYGFGLDYSLIAEAYINF
                     GSYGWIAIFFLCSLIAYFVRDVDFKRKDNLFSQYASLILLYSWFTLPRRKSYFIFNNF
                     FWYVLFFGLALILVSRSIKQRKEFKK"
     gene            13555..14322
                     /gene="wcyB"
                     /locus_tag="SPC25A_0014"
     CDS             13555..14322
                     /gene="wcyB"
                     /locus_tag="SPC25A_0014"
                     /note="member of homology group 172; old_tribe:0165 2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33967.2"
                     /db_xref="GOA:Q4K058"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K058"
                     /translation="MKISIIMGIHNGEKRFETAVQSIFNQTYDNWEFIICDDASTDKT
                     FEKLQGLYGQDSRFILLKNEKNVGLSATLNRCIEASSGEFIARMDDDDICYPERFERQ
                     VDYLFHHPEIDFVSSSIDIFDGEVVVGTRILLDFPSKKDLIWNSPFVHPVTMFRRDAL
                     LEVGGYRVSPETVRGQDYDLFMRLYSREKKGGNILEPLFRYTIDQNTMKRRTFKARIG
                     EMIIRYKGYRAMKVPFYNYVFIFKPLVAHLVTLVKRR"
     misc_feature    13564..14046
                     /gene="wcyB"
                     /locus_tag="SPC25A_0014"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 3.2e-39"
     gene            14322..15503
                     /gene="wcyC"
                     /locus_tag="SPC25A_0015"
     CDS             14322..15503
                     /gene="wcyC"
                     /locus_tag="SPC25A_0015"
                     /note="member of homology group 173; old_tribe:0166 2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33968.2"
                     /db_xref="GOA:Q4K057"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K057"
                     /translation="MFMKILITTHTYLPNKDGVQFVNQYLAEGLVKKGHQVTVLTYCY
                     PSRTRVPREVINGVRVIRWNARTSCTFHKGEKLAYQNFILNSQSDYDVLVNVGTQTAL
                     TDWLFPIFSQITIPKVLYIHSIWDFNWLHWHRQSFKRFVAKTWANVRWKYYYWKQTVI
                     FKQYNEVIQLHPKDYSVAFFKEKYDIESQILGNAADASFFQNKNAIKKQSYIVNVSNF
                     NDLKNQKKAVEYFLKSNLSSEWKFVLVGSEKNDYLQSVQDFEKELRNQLGITSGKEIE
                     YRIGLSREEVVKTVKEASFCLLTSIREAFPISLIEVMAAGIPFISSDVGIVNYLSGGI
                     TACSDQEFIRAIEEFATYPEVRNQYGKKGQMEAKEHYQVDDKVKEFETLLQKFVKEEE
                     D"
     misc_feature    14910..15419
                     /gene="wcyC"
                     /locus_tag="SPC25A_0015"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.2e-13"
     gene            15500..16465
                     /gene="wcyD"
                     /locus_tag="SPC25A_0016"
     CDS             15500..16465
                     /gene="wcyD"
                     /locus_tag="SPC25A_0016"
                     /note="member of homology group 174; old_tribe:0167 2"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI33969.2"
                     /db_xref="GOA:Q4K056"
                     /db_xref="UniProtKB/TrEMBL:Q4K056"
                     /translation="MKKIVFLCPYFGTLPPHTQLWLNSCKMNPSVTWYLFTDDKRTFD
                     YPENVQVFYTTLEETKALYQRKFDFEISLEGAYKLGDYKPLFGYLYEEMIQEFDAWGH
                     IDVYDEIYGDIRAFVTDELLDKYDKLMFFGHMGIYRNSPEVNRRFKLSSDLDRTYQEI
                     FSSSQFYNFEEYVAGSITRVYQKNGFPIGRLDKVIADLSGLSYHFRRGYYSDDFETFT
                     YLPNLPMIFSWEDGKTYCYSVQNNQVQKNEFLYVHFKRRKMIQSISNDVSAYLIVPNG
                     FVEMPKEITVDLIQKYSQKKLFYPVYFQEKWKGVKRLLKKIGRSE"
     gene            order(16462..16557,16565..17089,17122..17160)
                     /gene="wcyE"
                     /locus_tag="SPC25A_0017"
                     /pseudo
     CDS             join(16462..16557,16565..17089,17122..17160)
                     /gene="wcyE"
                     /locus_tag="SPC25A_0017"
                     /note="member of homology group 175"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyl transferase"
     gene            17151..18566
                     /gene="wzx"
                     /locus_tag="SPC25A_0018"
     CDS             17151..18566
                     /gene="wzx"
                     /locus_tag="SPC25A_0018"
                     /note="member of homology group 176; old_tribe:0168 2"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAJ84825.1"
                     /db_xref="GOA:Q4K055"
                     /db_xref="InterPro:IPR002528"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K055"
                     /translation="METKEKRLVNNTIIFTIGSLGSKFIQFLLVPLYTYTLTAAQFGI
                     TEILLTAVNLLIPVFSISIADGLLRFGLDKTLRRENVLKSAFIISILGTILSIISIPI
                     FSLYPTLSEWMVYFIIILNLRMYRDVFAIQLKVEGKNTLFACDSMIYTFVLSLASIVF
                     LVPFSLGISGYFFAYIVSNGISIFFILFFGGVWKSFTSGRFEKQLMIQLLKYSAPMIL
                     NGIAWWITNASDRFMLQWFMDDRAVGLYGVVAKLPLLIGTFTGVFNQAWIISAVEEFE
                     EENEEWFYQKVFHQYYAALFLSVSVFLLLLQPFMKVYVSPSFYEAWQYAPFLLLSSVV
                     SGIAAFMTGFYVAQKKNLNIIYTTIAGAFANILLNAMFIPMLGVLGASIATFLSWFVI
                     AIYRMKDVENFACFPLDKKVFWYLFLLCIQTITMTFLPILGIVFSVVLIPYFFYQEQE
                     FLAVLFDKGRKKVCSFKKSKR"
     misc_feature    17172..17975
                     /gene="wzx"
                     /locus_tag="SPC25A_0018"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 3.4e-10"
     gene            18539..19201
                     /gene="wcyF"
                     /locus_tag="SPC25A_0019"
     CDS             18539..19201
                     /gene="wcyF"
                     /locus_tag="SPC25A_0019"
                     /note="member of homology group 177; old_tribe:0169 2"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAJ84826.1"
                     /db_xref="InterPro:IPR015037"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ44"
                     /translation="MFIQKIKKIIRVFLRKSLVKDYRQRIQNKEFTLITSNCVGGLIS
                     HDLGLQFRSPTINMYIEAADFIQFCSHLERYLKEDLSFIEVNQDGHFVALCGDIKIYI
                     VHYNSFEEFAKKWSERAKRVDFDQLYLMMSERDGCRYEDIVKFDTLPYKNKVIFTSKK
                     MPEIQSAFYIPGIETKNNQKHKVKSVTTYLNSFTGKRYIDLFDFVEFLNTGRKQLSKY
                     EK"
     gene            19191..20273
                     /gene="gla"
                     /locus_tag="SPC25A_0020"
     CDS             19191..20273
                     /gene="gla"
                     /locus_tag="SPC25A_0020"
                     /note="member of homology group 96; old_tribe:0170 2"
                     /codon_start=1
                     /transl_table=11
                     /product="putative epimerase"
                     /protein_id="CAJ84827.1"
                     /db_xref="GOA:Q4JZ43"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR008089"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ43"
                     /translation="MKSKIILKNKTILVTGAAGFIGANLVMSLLQEENPLQIIGIDNL
                     NDYYDVSLKEYRLSTIQEECQSSLNKKWVFIKGDIADSDLMEEIFETYRPQIVVNLAA
                     QAGVRYSITNPDVYMKSNIIGFHTILEKCRKYQENIEHLVYASSSSVYGGNTKIPFSE
                     LDAVDNPVSLYAVTKKTNELEAHAYSKLYNIPTTGLRFFTVYGPAGRPDMAYFSFTKQ
                     LIDKKPIEIFNYGNCQRDFTYIDDIVEGVKRVMTGAPQKEIGEDGLPIPPYAIYNIGN
                     HQPENLLNFVEILQEKLIAASILPEDYDFSSAQKLVPMQAGDVVATYADISLLEKDFN
                     FKPKTSLRNGLRNFAEWYRNFYQRGE"
     misc_feature    19221..20252
                     /gene="gla"
                     /locus_tag="SPC25A_0020"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00023"
     misc_feature    19224..20015
                     /gene="gla"
                     /locus_tag="SPC25A_0020"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 8.3e-55"
     misc_feature    19224..20129
                     /gene="gla"
                     /locus_tag="SPC25A_0020"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 7.1e-05"
     misc_feature    19227..20093
                     /gene="gla"
                     /locus_tag="SPC25A_0020"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 5.4e-09"
     gene            20233..21501
                     /gene="ugd"
                     /locus_tag="SPC25A_0021"
     CDS             20233..21501
                     /gene="ugd"
                     /locus_tag="SPC25A_0021"
                     /note="member of homology group 20; old_tribe:0020 15"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAJ84828.1"
                     /db_xref="GOA:Q4JZ42"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ42"
                     /translation="MQNGIEIFIKGVNRMKITVVGMGYVGLSLAVLLAQHHEVTALDI
                     IDKKIQLINEKKSPIQDEYIEQYFLEKNLHLSATTNEVEAYKDAEMIIIAAPTDYDTH
                     KNFFDTSAVEQVIENIISMNNEALIVIKSTVPVGYTESIREKYGKKNILFSPEFLREA
                     NGLYDNLYPNRIIVGTDLNDGALVSKAHEFVSLLQEGALKENIDTLIMGFSEAEAVKL
                     FSNAYLALRVSYFNELDTYAELKGLNTKAIIDGVGLDPRIGQFYNNPSFGYGGYCLPK
                     DSKQLLSNYHDVPENIISAIVSSNETRKKFIAERILEIVGANHIDEYYNLKQEIVVGI
                     YRLVMKKGSDNFRHSSIQGIIKRLKANGVTLMIYEPSLPDGQLFFGSEVVHDFPKFKE
                     KSHLIVANRFDETLMDVKDKVYTRDLFGRD"
     misc_feature    20275..20673
                     /gene="ugd"
                     /locus_tag="SPC25A_0021"
                     /note="HMMPfam hit to PF01210, NAD-dependent
                     glycerol-3-phosphate deh, score 0.0013"
     misc_feature    20275..20832
                     /gene="ugd"
                     /locus_tag="SPC25A_0021"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.3e-45"
     misc_feature    20860..21141
                     /gene="ugd"
                     /locus_tag="SPC25A_0021"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.6e-35"
     misc_feature    21241..21480
                     /gene="ugd"
                     /locus_tag="SPC25A_0021"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 8.5e-05"
     gene            complement(order(21633..22214,22271..22956))
                     /gene="tnp"
                     /locus_tag="SPC25A_0022"
                     /pseudo
     CDS             complement(join(21633..22214,22271..22441,22441..22956))
                     /gene="tnp"
                     /locus_tag="SPC25A_0022"
                     /note="member of homology group 13; old_tribe:0015 22"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
     misc_feature    complement(join(22134..22214,22271..22441,22441..22464))
                     /gene="tnp"
                     /locus_tag="SPC25A_0022"
                     /note="HMMPfam hit to PF01610, Transposase, score 1.2e-31"
                     /pseudo
     gene            23942..25219
                     /gene="intron"
                     /locus_tag="SPC25A_0023"
     CDS             23942..25219
                     /gene="intron"
                     /locus_tag="SPC25A_0023"
                     /note="member of homology group 108; old_tribe:0103 3"
                     /codon_start=1
                     /transl_table=11
                     /product="putative group II intron protein"
                     /protein_id="CAJ84830.1"
                     /db_xref="GOA:Q4K051"
                     /db_xref="InterPro:IPR000477"
                     /db_xref="InterPro:IPR013597"
                     /db_xref="InterPro:IPR015706"
                     /db_xref="UniProtKB/TrEMBL:Q4K051"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYDFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     misc_feature    24116..24766
                     /gene="intron"
                     /locus_tag="SPC25A_0023"
                     /note="HMMPfam hit to PF00078, Reverse transcriptase
                     (RNA-dependent DNA pol, score 6.4e-63"
     misc_feature    24812..25063
                     /gene="intron"
                     /locus_tag="SPC25A_0023"
                     /note="HMMPfam hit to PF08388, Group II intron,
                     maturase-specific domain, score 3.5e-30"
     gene            complement(order(25279..25752,25754..26080))
                     /gene="tnp"
                     /locus_tag="SPC25A_0024"
                     /pseudo
     CDS             complement(join(25279..25752,25754..26080))
                     /gene="tnp"
                     /locus_tag="SPC25A_0024"
                     /note="member of homology group 4; old_tribe:0004 68"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(25690..25752,25754..26062))
                     /gene="tnp"
                     /locus_tag="SPC25A_0024"
                     /note="HMMPfam hit to PF01710, Transposase, score 2.2e-23"
                     /pseudo
     gene            26341..26442
                     /gene="tnp"
                     /locus_tag="SPC25A_0025"
                     /pseudo
     CDS             26341..26442
                     /gene="tnp"
                     /locus_tag="SPC25A_0025"
                     /note="member of homology group 0019 18; member of
                     homology group 0022 16; old_tribe:0171 2; old_tribe:0021
                     15"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
                     /db_xref="PSEUDO:CAJ84832.1"
     gene            order(26442..26657,26674..27165)
                     /gene="tnp"
                     /locus_tag="SPC25A_0026"
                     /pseudo
     CDS             join(26442..26657,26674..27165)
                     /gene="tnp"
                     /locus_tag="SPC25A_0026"
                     /note="member of homology group 19; member of homology
                     group 19; old_tribe:0171 2; old_tribe:0021 15"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
     misc_feature    join(26586..26657,26674..27048)
                     /gene="tnp"
                     /locus_tag="SPC25A_0026"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 0.0004"
                     /pseudo
     gene            27311..28294
                     /gene="tnp"
                     /locus_tag="SPC25A_0028"
                     /pseudo
     CDS             27311..28294
                     /gene="tnp"
                     /locus_tag="SPC25A_0028"
                     /note="member of homology group 39; old_tribe:0051 6"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1239 transposase"
     misc_feature    27815..28249
                     /gene="tnp"
                     /locus_tag="SPC25A_0028"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 1.1e-18"
                     /pseudo
     gene            28371..>28466
                     /gene="aliA"
                     /locus_tag="SPC25A_0029"
     CDS             28371..>28466
                     /gene="aliA"
                     /locus_tag="SPC25A_0029"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAJ84835.1"
                     /db_xref="UniProtKB/TrEMBL:Q20WL5"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSAK"
BASE COUNT     9440 a   4391 c   5655 g   8980 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa cactgcggct aaagaagtac ttgaaaaaca
      121 ggtcttggct ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcatat aaaaacaagg gaggactgta taaaaagcag aaatcctttg
      241 ttttttataa ccaaggttta taaactttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gatgaacata aagaagcgtg tccttagtgc aggtctgact
      361 tttgcatctg ctttgctttt agctgcttgc ggccaatcag gttcagatac aaaaacttac
      421 tcatcaacct ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat
      481 aatacattga ttatcaccaa tctagttgat ggtttgcttg aaaatgacaa tcacggaaac
      541 ctagttccat ctttgccaga ggactggtct gtttcgagcg acggtctgac ttatacttac
      601 aaattgagaa aagatgccaa atggttcaca gctgacggtg aagagtactc cccagtcaag
      661 gcccaggatt ttgtgacagg tatcaagtac gtagtggata ataaatcaca ggctattgac
      721 ttgattcaaa actcgatcaa aggtttgaat gattatatta caggagcgga ttctgacttt
      781 tctaaggttg ggatgaaggc cattgacaac cagactgttg agtatacttt ggtacgccca
      841 gaaccttact ggaactcaaa aacaaccaac agtattcttt tcccggtaaa ctaagagttt
      901 ctaaattcaa aagggaaaga ttttgggacc ctatctccag atagtattct ctacagcggt
      961 ccttatttgt taaaagattt cacatcaaaa tcatttatcg agtatgtgaa aaacccacat
     1021 tactatgatc atgccaaagt atcgattgaa cacgtgaaat tggcttactt taatggatca
     1081 gatcaagaat tgactatccg taactttgaa agtggagctt attctatcgc tggagtttat
     1141 ccaaatagtt cgaactttgc taagaccaag gagaaatata aggataatat cgtctatagc
     1201 ttgcaggaca agacttcttg gtatttaaat ttcaatgtca atcgcgaggc ttgcaatcac
     1261 actactaaaa cgacagatga gccgaagaag tcaactgaga cagctgtctt gaacaaaaac
     1321 ttccgccaag cagtaaactt tgccttggac cgcacagccc attctgccca gtcaaatggg
     1381 gaagaggcgg ctagcaagac ccttcgtaac accttggtgc tcctacattt gtccaagttg
     1441 gagacaagac ctttggagaa gtagttgctt ctaaattggt caactatggt acagaatgga
     1501 ggtattgact tggcagatgc tcaggatgcc tatttcaaca aagaaaaagc ccaagcaaaa
     1561 tttgcggaag ctaaaaaaga attggcaagt caaggtgtga ctttccctat tcacgtgaat
     1621 gtggcagtag atcagacaag taaaaatgcc gttacaggca tgaactcagt taagcagact
     1681 ctggagtcag ttttaggtgc tgataacatt gttattgatg ttcagcaact ttcaacagat
     1741 gattttaata atgtaccttc ttggcaccga tgccagctga tagaggctat gatttgagct
     1801 ttgatggttg ggtgggtgac tatcaggatc catcaactta tctcaatcct ttcaatgcag
     1861 agaatggctt ctatctcaaa atttttggac cggatgccaa ggaagataag gaaaaaatca
     1921 ctagcctagg tcttgatacc tacactaaga tgctcaaaga tgcagatagt gaaaacaaag
     1981 atgtagccaa acgctatgaa aaatatgctg aagcacaggc ttggatgatt gacaattctc
     2041 tcattatgtc agctatgtca agtggtggca cagcatctgt aaccaaagtg atgccattta
     2101 caagagggca ttaattggtt ggtattaagg gtgatggcaa taactacaag tacatgaaac
     2161 tgcaaaaaga tactgtaaca accaaacggt ttgaaaaagc taagaccaaa tgggagcaag
     2221 aaagcaaaaa agcaatcgaa aaagcccaaa aagaagcaga aaaacatgtt aaatagttat
     2281 aaatagcttt ttcaaggaga attaaaaaga caaacatcag ttttggtgct tgtcttttta
     2341 aatcactcgg ttattgaaaa ttagacttct tgcgaaacag gctctttgtc aactgtagtg
     2401 ggttgaagaa aagctaagct cgagaaagga caaatttcgt cctttctttt ttgatattca
     2461 gagcgataaa aatccgtttt ttgaagtttt caaagttccg aaaaccaaag gcattgcgct
     2521 tgataagttt gatgagatta ttggtcgctt ccaatttggc gtttgaatag ggtagttgaa
     2581 gggcgttgac gattttctct ttgtccttta gaaaggtttt aaagacagtc tgaaaaatag
     2641 gatgaacctg cttaagattg tcctcaatga gtccgaaaaa tttctcaggg tctttgttct
     2701 gaaagtgaaa aagtaagagt tgatagatct gatagtggtg tttcaagtct tctgaatagc
     2761 ttaaaatctt gtcaagaatt tctttatttg ttaagtgcat gcgaaaagta gggcgataaa
     2821 atcgcttatc actcagttta cggctatcct gttgaatgag tttccagtag cgcttgatag
     2881 ccttgtattc atgggatttt cgatgaaact gattcatgat ttggacatgc acacgactca
     2941 tagcacggct aagatgttgt acaatgtgaa agcgatcaag aacgatttta gcattcggga
     3001 gtgaaacagc ctgggagact gtttcagcct gagcctagaa atttgaaagc gaagctgttt
     3061 agccaagtca tagtaagggc taaacatatc catagtaatg attttgacgc gacatcggac
     3121 ggctctatca tatttaagaa agtgatctcg gatgacagct tgtgttctac cctcaagaac
     3181 agtgatgata tcgagctttt caaaatcttg cgcaataaag ctcatctcca tctcccgatt
     3241 gaaacagtca ctccccggac tgtttcaacg tcccaggaca taatctcagg aagacaagaa
     3301 aaatcatgtt taaagtgaaa atcattgagc tttcgaatga cagttgaagt tgaaatggcc
     3361 agctgatggg caatatcggt catagaattc ttttcaatta acttttgagc aatcttttgg
     3421 ttgatgatac gagggatttg gtgattcttc ttgacgatag aagtttcagc gaccatcatt
     3481 tttgaacagt gatagcactt gaatcgacgc tttctaagga gaattctagt aggcatacca
     3541 gtcgtttcaa gataaggaat tttagaaggt ttttgaaagt catatttctt catttgactt
     3601 ccgcactcag ggcaagatgg ggcgtcgtag tccagtttgg cgatgatttc cttgtgtgta
     3661 tccttattga tgatgtctaa aatctggata ttagggtctt taatgtctag taattttgtg
     3721 ataaaatgta attgttccat atgaatcttt ctaatgagtt gtttgatcgc ttttcatttg
     3781 gccactcttc aatatgtgcg agaatatcgc acttatgaac aaattgcggc tgattttggt
     3841 attcacgaaa gcaacttaat ccgtcggagc caatgggttg aagtaactct tgttcaaagt
     3901 ggttttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
     3961 gaagtaaaaa tcaatcgccc taaaaaaaga attagcaaat tattctggta aaaagaaatg
     4021 ccgcgctatg gaaaaatgat ttgttttgtg ctaaaataga ttgaaactaa tactcaatga
     4081 aaatcaaaga gtaacttgga agttagctca aagtacagct ttaaggtggt agatagaact
     4141 gacgaagtca gctcaaaata ctgttttgag gttgcagatg gacgctgacg tggtttgaag
     4201 agattttcga agagtataag atcctctctt ttgctatagt taaggagatg agaggtaaat
     4261 gataagggag agactatgta cgactatcta atcgttggtg ctggtttgtc gggagcaatt
     4321 tttgcttatg aagcaaccaa gcgtggaaaa aaagtaaaag ttattgataa acgtaaccac
     4381 attggtggaa atatctactg tgagaatata gaaggagtta atgttcataa atatggtgca
     4441 catatcttcc atacttctaa taagaaagtc tgggattatg tgaatcaatt tgctgaattt
     4501 aacaactaca tcaactcgcc tgtagctaat tacaagggta gcctttataa tctacctttc
     4561 aatatgaata ctttctatgc tacgtggggg acaaaaactc ctcaagaagt gaaaaataag
     4621 attgctgagc aaacggctca catgaaagac gttgaaccga aaaacttgga agaacaggct
     4681 atcaagttga tcggtccaga tatttatgaa aagttgatta aaggatatac tgaaaagcaa
     4741 tggggacgtt ccgcgactga ccttccaccg tttatcatca aacgtctacc agttcgtttg
     4801 acttttgata ataactactt taatgaccgt taccaaggta ttccaatcgg tggctataat
     4861 gtcattatcg aaaatatgct gaaaggtgtt gaagtagaac ttggagttga cttttttgcc
     4921 aatcgtcagg aattagaagc ttctgctgaa aaagttgtct ttacagggat gattgaccaa
     4981 tatttcgatt ataaacatgg tgagctagaa taccgtagtc ttcgttttga gcatgaagtt
     5041 ctagataagg aaaattatca aggaaatgcc gttgttaatt atacagaacg agaaattcct
     5101 tatactcgca ttattgagca caaacatttt gagtacggaa cacaagataa aacggttatt
     5161 actcgtgaat acccagctga ttggaaacgt ggagatgaac cttattatcc aatcaatgat
     5221 gagagaaaca atgccatgtt tgctaaatat caagaagaag cagtacagaa tgataaggta
     5281 attttctgtg gacgtttggc tgattataaa tactacgaca tgcatgtggt tattgaacgg
     5341 gctttggaag tggtaaggaa tgagttctca tgagagaaac aggcatatat gaaagttaat
     5401 gtagaggagt tgagcttttt atttgaatat tgggtgaaaa agtagtatac ttagatagtc
     5461 tgtttttaaa aatcaaaatg gggaaatcga ttcttatcaa cttcagagtg aactgaatta
     5521 aaactgcata ggagtatata aaatgctgaa gtaagattta cagaacatgg tatgataagt
     5581 gttcgacagc ttgtttggca ggagttcgaa tattcaagta attgagaggg tttttgaact
     5641 tctgataaga tagatagtag attactttcg agtaaaggat agttgagaaa atgaataatc
     5701 gtatagtaga catcagtttg tttgatttat tgaatgtctt atggcttcgt aaatggatca
     5761 ttgtttttgt atcatttgtt tttggatgta tttctttttt atattatcaa ttttttgtac
     5821 ccaaaaccta tacaagtgat actcgtatat atgtggtaag caaaggggat aataaaaatc
     5881 tgtctaatgc agatttgcaa gcaggaagtg ctctaacaaa ggattacaaa gaaatcattt
     5941 tatcagatga agtgttagaa gaaacaattt ctgatttaaa actagaatca actttggaat
     6001 ctctagcttc gaaaattaaa atttctatcc ctgcggaaac tcgaattatt tccattagtg
     6061 ttacaaatac gaactcagat gaagctgctc gaatagcaaa tgggataagg aaggtagctg
     6121 cccttaaaat caaggaagta actcaagtta cagatgtcac cactttacag actgcacgcc
     6181 ctccccaaac tccgtcagga ccgcatgtgc gaaaatctac tacagcaggg cttgttcttg
     6241 gtgcattctt aacagtcttt ctagtagttg ccaaggaaat attagatgat cgcataaaac
     6301 gttttgaaga acttgaaaaa ttgggaatcc ctattttagg ctcaatacct ttatcaaaaa
     6361 atataaagta gaaaatcatg ggaaaattag aactaacacg taagtactat caattgtaca
     6421 atgaaacgaa agaatatttt aatgccttac agaccaatat tcaacttagt ggtgatggac
     6481 tgaaagtcat ttctgttact tccacagtaa aaaacgaagg caaatcgact atatcagttg
     6541 gcttgtccat gtccttggcc ttatcaggct ataaagtcct gttactggat gtggatttac
     6601 gtaattcagt gatgtcagga atgtttcatt ctagggaaag aataacaggt ttgactgaat
     6661 atttatctgg caaagcggga atggcggatt ctatgcagga aactacttta gataatctct
     6721 atatattaca agcaggagtc gtttcaccga atcccttatc tctattaagg agtgttaagt
     6781 ttgaaacctt gatagattct atgaaaaagt actttgacta tattatagta gatactccac
     6841 caatcggcca agtaatagat gctgcaatta ttgcccaaca atgtgatggg atatttttgg
     6901 tcactgaaat gaggaaaacg acacgcagac aaattttttc ttccctccag caattggaac
     6961 aaactggagt tcccgttttg ggccttgtgg ccaataaagc aattataaaa aaagatagct
     7021 atggctatta tggaaaaaac accgcgagcg agactgaaag atattgatgg actacctcct
     7081 ctacctcaca aattgcattt tttgtgaggt agaggagtaa gttgatacta ttatatatta
     7141 gacttcctgc gaaacaaaat atggtatagt agttctatga attatgaagc aagtaaacaa
     7201 ctaactgatg cacgatttaa gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg
     7261 ttagctgtat taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa
     7321 ttaagcctag aagaccttct tatggctact cttcaatatg tgcgagaata cccacttatg
     7381 aagaaattgc ggctgatttt ggtattcacg aaagcaactt actccgtcgg agccaatggg
     7441 ttgaagtaac tcttgttcaa agtggtgtta cgatttcaag aactcctctc agctctgagg
     7501 acacggtaat gattgatgcg acggaagtac aaatcaatcg ccctaaaaaa agaattagcg
     7561 aattattctg ataaaaaaaa tgccacgcta tgaaggctca agcgattgtc acaagtcaag
     7621 ggagaattgt ttctttggat atcgctgtga actatttgtt atgatatgaa gttgttcaaa
     7681 atgagtcgca gaaatatcgg acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg
     7741 ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact caagccgcta
     7801 acagctgaag ataaagcctg taaccatgcg ctatccaagg agagaagcat ggttgagaac
     7861 atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa
     7921 cgcttcggat tacgaatgaa tttgattgct gctattatca atcatgaact aggattctag
     7981 tttggcagga agtctatttt ggaatgctat tatgtttagt tgtgctcaat gaaaatgaaa
     8041 gaactagtaa gctaggcgca gtcagctcaa aacagtgttt tgaggttgta gatagaactg
     8101 acgaagtcag taacatatat atgacaaacc gatgctgacg tggtttgaag agatttttga
     8161 agagtataag acggtatttt aagggaatga ttactatttg aggtatttta tgagtagaga
     8221 gaaaaaaaga ggaacagcag tccacttgaa atcttatatc aatagtgtgc tgctaatcct
     8281 gtacacagga atagcgagcc tatttctttt tcagatattc cgatacaata ttttaaattt
     8341 taggaatctc aatttattag tagctctgct agtagtattg gtatttattt taggagtgag
     8401 tttgattgtc cgaaaaaaag ctgaaaagtt gacaatgctt ctcctaatct tagctgtcgc
     8461 aagtagttca atatcgcttt tggctgttca acaatttatc ggttttacaa gtcgcttaaa
     8521 tgcaacttca aacgtttcag aatatgctat tagtcttgta gttttgaaag atagcgaaat
     8581 tagtgaacta gaacaagtat cacatgtgat ggcgcctacc gatacagatt atgaagctat
     8641 tcaaagtttg ttagcagata taaaagaaaa gcaaggtaaa gatctaatag tagataaaag
     8701 caaatcttat ttagaagcct ataagagttt gatttcaggt gacaccaagg tgattttttt
     8761 aaatagtatt tttgaacata tgattgagtc ggattttcct gactttagag acaaaattaa
     8821 gaaaatatat acaaaagaaa tgacaaagaa agtagaagct ccaaaggttt caaaggggca
     8881 ggcttttact atttatttca gtgggattga tacttatgga ccaattaact ctgtatcacg
     8941 ttcggatgtc aatattttga tgacagtcaa tagcgagacc aaaaaaattc ttttgacaac
     9001 tacacctcgt gactcctatg tcgcaattgc agatggagga aagaatcgaa aagataaatt
     9061 gactcatgct ggaatttatg gtattgattc ttccattcat accttggaac atttatatgg
     9121 tgtagagatt aactactatg ttcgtgtaaa tttcacctct ttcttaaaga tagttgattt
     9181 attgaatggt attgatgtgg acgatagtca agaatttaca attgacggga acgactatcc
     9241 tgttggaaat ctccatctaa attctaagtc agcacttggt ttcgttcgag aacgtcattc
     9301 tctagcagat ggagatcgtg atcgaggacg gaatcaacag aaggtgctcg ctgcaattat
     9361 tcaaaaatta acctcaatag aatcattgaa aaattatcgt caaatcatgc aaggattaga
     9421 ggattcaata caaacaaatc tctctccaac aactatcatg gacttagcca atactcaatt
     9481 ggaaagtgga gggaattata aaataaattc tcaagattta aaagggacag ggcggatgga
     9541 tcttccttct tatgcaatgc ctgatagtca gttgtatatg atggaaattg atgagaatag
     9601 cctctcagct atcaaagaaa atattcaggc tgttctggag ggtaggtaag atgatagatg
     9661 ttcattctca cattattttt gatgtggatg atgggccaaa gtccatagaa gatagtagag
     9721 ctttgttgtt agaagcctat gatcaaggaa ttcggacaat tgtttcaaca tcccaccgcc
     9781 gtcaaggtat gtttgaaaca ccagaagaca agattgcgga aaattttcgt gcggtacaga
     9841 aaatagctag agatattgca gatgatttaa caattttata tggtgcagaa atctactata
     9901 ctcaagacat tatcaataaa cttgaaaaga aaactttccc aactttaaat gggagtcgat
     9961 atgccttgat tgaatttagt agcgagactt cttatcgttc tattcatagc gctcttcagc
    10021 agttgctttt gtcaggaatt accccgctta tcgcccatat cgaacgttat gatgctcttg
    10081 aaaacaataa acaagcagtt ctcgaattga ttcgtatggg ctgttataca cagattaata
    10141 gttcccatct actcaaaaaa aaattattta aagatgatgc aaaaatcatg aagaaacgag
    10201 ttcactattt tttgaaacat gatttagtcc atattgtagc aagtgacatg cataatcttg
    10261 atactagacc gccttatatg gcggaagctt atgaaatcat ttctaaaaga tacggaaaag
    10321 aaaaagctga agaatttttt ataaaaaatc cgcaacgaat cctaatggat caattgattt
    10381 aatgaaaaag gaaacaacaa atgtataaag ttatcaaacg atttatagat atagctttag
    10441 ccttgctagg aattgtatta ttatcaccac tatttttagg aattatagtg ttcataaaat
    10501 tagaatctaa agggcctatt ttctttaaac aaaaaagaat tgggctacat aaaaaagaat
    10561 tttacattct aaaatttaga acgatgagaa ttgacactcc ttcagctgtc cctacacatc
    10621 ttttaaaaaa tccttatcaa tggattacaa aggttggtaa agtcttacgt agaacctctc
    10681 tggatgaatt gccacagatt tggaatattt tggtcggtca catgtcgctt gtaggaccaa
    10741 gacctgccct ttggaatcaa tttgatttga ttgaagaaag agacaaatat ggagcaaatg
    10801 atattttacc tggtttaaca ggttgggcac aaatcaatgg aagagatgaa ttatctattc
    10861 cagtcaaagc caaatttgat ggctactatg tgaagaactg ttcatttgtt ttagattgtc
    10921 gatgtgttgt agaaagtttt ttagtagtat ttaagagata tgggcatcga gaaggtggtg
    10981 cagattagag gaactgatat atgggaaatc gtaaaaaagt ttttgtagta gccaatgtag
    11041 tcaaagaaca tattctaaaa tttcacattc cgactatcaa agaaatgaca aaaagagggt
    11101 ggacggtaga cgtaggtgct tctggggatg aaacagttcc ctattgtcac caacaatatt
    11161 cactgcccca ccaacgttct ccgtttcatc taggcactct caaaagtatc tggaaattga
    11221 gaaaaatttt gaagtctgga ggctatgata ttgtttactg tcatactcct gttggaggtt
    11281 tggtgggacg actggcttct ttaggattgc gaaaacaagg aacaagagtc atttattttg
    11341 ctcatggata tcatttttac aaaggagcaa cttttttcaa ttggttagtg tattacccaa
    11401 ttgaaaagct actgtccctt tttacagata gtatcattct aatcaatcaa gaagattatc
    11461 atctcacaaa aacaaaattt aaacaggttc aatcctatct agtgagtgga atgggagtaa
    11521 aacaagaacg gttttcaccc caatcaaatc aagttagaga acgttatcgt aaagaattga
    11581 aactgcctga ggatgcgact gttttaattt attgtgctga gctaataaaa aataaaaatc
    11641 aaacattttt acttcatgct atgaaaaagc ttgtggatca gggagagaat ctttattgct
    11701 tattagtagg aattgattat accaagggtg aaatggtaga atgtattcaa tccttgaatt
    11761 tatccgatcg agttttactt ttagggtgga gagaagatat tgccaatctt tacgcttgtt
    11821 ctgatatatg tgttgcaaca agtattcgag aaggatttgg attaaatata gtggaagcaa
    11881 tgttttgtca cgttccagtt gttgcgacca tcaatagagg acacgccagt attatacaag
    11941 atggacaaaa cggtctatta gtccaattag gaaatacaaa gcaattagta gaggctattt
    12001 atgtactaat gaaggatact aagaagaagc aagaattagt ggagcaagct agtgcgaatt
    12061 tagaacaata tcatagtcag aaaattgtaa atagcttact agaaataata gaacagactg
    12121 caatgaagtg agtgaaggat gtgaaaaagt gaaaatacaa attgataaaa tatactatct
    12181 atttttttgg ctggtagttt cctttggata tttttttatg atgccaacct ttacagaaga
    12241 tttagaaggc gttgtcagtg ctagtttagt acaattgtta ttatttatta taggatatgt
    12301 atatgtatct tatttaaatc gttcttttat ctcactgtat agtatcttta tgattgtgtt
    12361 ttaccttttt caaaatggac aggtattgtt atattcactt ggagtagagt atgattactt
    12421 ttatgtttta agatatgatg aaaccatcgt actacaatca gttatttttt caacacaatg
    12481 tcttattgca gcctttatgg ctggagtctt ttctacgaag aaagaggtat caaaacccct
    12541 ttattcttat atggatcaat tagaacgaga aaaactgatt actgctggaa agttattttg
    12601 gggtgcgttt gcgatttttg ctttaccctt tatgatgatg aagtttgtta tcaccagtac
    12661 atctgggtat tttgcgatga tacgtttcgt tggaagccta cctacaataa cagtgttatt
    12721 tgaaaaaatg ttcattgctt caagtgtttt tttggttgtt tatttaaaat ctgaggaaac
    12781 ttggagcaag tttttaaaag ttgttatctt aggttggagt ataatggctg ctttaacagg
    12841 agatagaacc gtaggtttag cagggattgt tacgttagct ttaattcaaa cattaattgg
    12901 taatcgtaaa aaaaagatta agttttctca gtatgccttg ttagttgggg cagctgttgt
    12961 agtgatgtat ttaatgtcct ttgcttttca atttaggatg caacaagatt ctaaagtttc
    13021 aggactacaa actgcggtag tagaaatgat aggaactcta gggtttagtt ttttcccact
    13081 cgtattaacg attagaattg ttccaacttc tattaacttt tttagaggaa aatcatatat
    13141 tgcagccatc attacaggac taattccatc taattttgat tttttacatt taacaaagac
    13201 attatcagaa tggaatgcat atccaacgga attattagat acaatctatc attatggttt
    13261 cggattagat tattctttaa ttgcggaagc ctatattaat tttggttctt atggatggat
    13321 agcgattttt ttcctttgtt ctctaatagc ttattttgta agagatgtgg attttaaaag
    13381 gaaggacaac ttattctcac aatatgctag cttgattttg ctgtattcat ggtttaccct
    13441 tccaagaaga aaatcttatt ttatttttaa taattttttt tggtatgtat tattttttgg
    13501 actagcactc atacttgtct ctcgttctat taaacaacga aaggaattta aaaaatgaaa
    13561 atttcaatta ttatgggcat tcataatggt gaaaagcgct ttgaaacagc tgttcaaagt
    13621 attttcaatc aaacttatga taattgggaa tttattattt gtgatgatgc ttccacagat
    13681 aaaacgtttg aaaagttaca aggattatat ggacaggatt cacgttttat cttattaaaa
    13741 aatgaaaaaa atgtaggtct ttccgcgaca ttaaaccgtt gcattgaagc aagtagtgga
    13801 gaatttattg ctagaatgga tgatgatgat atttgttatc ccgagcgctt tgaaagacaa
    13861 gtcgactatt tgttccatca tccagagatt gattttgttt cttcatctat tgatattttt
    13921 gatggagaag tagttgtagg tacacggatt ttacttgatt ttcctagtaa aaaggatttg
    13981 atttggaata gcccctttgt tcatcctgtt accatgtttc gtagagatgc cttgcttgaa
    14041 gttggcggtt atagagtttc tccagaaact gttcgtgggc aagattatga tttgtttatg
    14101 agactatatt cacgcgagaa aaaaggtgga aatattttag aaccactatt tcgctatacg
    14161 attgatcaaa atacgatgaa gcgacgtacg tttaaagctc gaattgggga aatgattatt
    14221 cgctataaag gttatcgtgc gatgaaagtt ccattttata attatgtttt tatatttaaa
    14281 ccattagtag ctcatctagt aacactcgtt aaaaggagat aatgtttatg aaaattttaa
    14341 taaccactca tacttatctt cctaataaag atggtgttca atttgttaat caatatttag
    14401 cagaaggatt ggttaaaaag ggtcatcaag taacagtgct gacctattgt tatccatcac
    14461 gtacaagggt acctagagaa gtgataaatg gtgttagagt cattcgttgg aatgctcgaa
    14521 caagctgtac tttccataaa ggagaaaaat tagcttatca aaatttcatc ttaaattccc
    14581 aatcggatta tgatgtttta gtgaatgttg ggacacagac tgctttaaca gattggttat
    14641 ttccgatatt ttctcagata acaattccaa aagtcttata tattcattcg atatgggatt
    14701 tcaactggct gcattggcat agacaatcat tcaagcgatt tgttgctaaa acttgggcaa
    14761 atgtacgctg gaaatattat tattggaaac agactgttat ctttaaacaa tataatgaag
    14821 taattcagct acacccaaaa gattatagtg tggctttctt taaagaaaaa tatgatatag
    14881 aaagtcagat tttaggaaat gccgctgatg cttccttttt tcaaaataaa aacgctatca
    14941 aaaagcaatc ttacattgta aatgtttcta attttaatga tctaaaaaat caaaagaaag
    15001 cggttgagta ttttttgaaa agcaatcttt caagtgagtg gaagttcgtt ttagttggtt
    15061 cagaaaagaa tgattattta caaagcgtac aagattttga aaaagaactc cgaaaccaat
    15121 taggtatcac ttctggtaaa gaaatagagt atcgcatcgg attgtcaaga gaagaagttg
    15181 taaaaactgt aaaagaagcc tctttttgtt tactgacgag tatacgggaa gcttttccaa
    15241 tttcattaat tgaagtaatg gcagcaggaa ttccttttat ctcttctgat gtaggaattg
    15301 tcaactattt gtctggagga atcactgctt gtagtgatca agaatttata agagctattg
    15361 aagagtttgc tacttatccc gaggtcagaa atcaatatgg caaaaagggg caaatggaag
    15421 cgaaagaaca ttatcaagta gatgataaag tgaaagagtt tgaaactttg ttacaaaagt
    15481 tcgtaaagga agaagaagat tgaaaaaaat agtatttttg tgtccctatt ttgggacttt
    15541 accaccccat acgcagttat ggttgaattc ttgtaaaatg aatccgtctg taacatggta
    15601 tctatttaca gatgacaaga ggacatttga ttatccggaa aatgtgcaag ttttctatac
    15661 tactttggaa gaaacaaagg cgttgtatca aagaaaattt gactttgaga tttctttaga
    15721 gggtgcttat aaactaggag attataagcc tttattcggc tatctttatg aggaaatgat
    15781 acaagagttt gatgcttggg gacatattga tgtttatgat gaaatctatg gagatattcg
    15841 tgcatttgta acagatgagt tattagataa atacgataaa ttgatgtttt ttggacatat
    15901 gggtatttat agaaattctc ctgaagttaa tcgcagattt aaattatcgt ctgatttgga
    15961 tcgtacttat caagaaatat tttcttcatc acaattttat aattttgaag aatatgttgc
    16021 aggaagtatc actcgtgttt atcaaaaaaa tggattccca ataggaagat tagataaagt
    16081 gattgcagat ctttctggtt taagttatca tttccgacgt gggtattatt cagatgattt
    16141 tgagacattt acctatttac caaatctacc tatgattttt tcttgggaag atggaaaaac
    16201 ttattgttat tcggtacaaa acaatcaagt gcaaaaaaat gagttcttgt atgtacactt
    16261 taagcgtaga aaaatgattc agtctatttc aaatgatgtt tctgcttatt taatcgttcc
    16321 aaatggtttt gttgagatgc ctaaagagat aactgttgat ttgattcaaa aatatagtca
    16381 gaaaaaatta ttttatccag tctattttca ggaaaagtgg aaaggtgtca aacgattatt
    16441 gaagaaaata gggaggtcag aatgaaggac attttaaaaa agttgataca acaattaccg
    16501 gataaactat ttctacaaat taaatactac tacgttttta aaaaagaaat taaatttaca
    16561 gaatcctaaa acctttaata aaaaaacaca atgattaaaa ttatataatc ggaaaccttt
    16621 ttatacaatt ttagcggata aaattttagt gaagaactat attgcccata tacttgggga
    16681 agaaaatatt attccgactc tgggtgttta taatcgtttt gatgagattc attttgtttc
    16741 gcaggaagtc tattgaagaa tttgtaacag atgagtcgaa acgagaatta aaggaatata
    16801 agattgtttt ctttatactg ttcctaagtt ttttcaatta gattataacc gctttacaaa
    16861 tcataagaga aatatttatg ataccaacta gaatcagcag gactttattt atgcttaccc
    16921 atcaagtaaa gataagataa tagatagtcc cgctggactt actgcaatac tcgagtttgc
    16981 gagtaaatta tcaaaagata ttccattttt gaggtgcgat ttttatattg tgaatgataa
    17041 aatattattt gaagagatta cgttttttcc agaatcaggt tttggaaaat ttagtccaga
    17101 gcattataat ttagagtttg gaaaggatat tactttactg gagaagcaag atggaaacaa
    17161 aagaaaaacg tttagtgaat aatacgatta tttttacaat tggaagttta ggttcaaaat
    17221 ttatacagtt tttgttagta cctttatata cctatacttt aacagctgct cagtttggga
    17281 ttaccgaaat tttattaacc gctgtgaatc ttttaatacc tgtattttct atttccattg
    17341 ctgatggatt attaagattt ggattagata agaccttaag aagagaaaat gtcttgaaat
    17401 cagcttttat catttcgata cttgggacta ttttatccat tatttcgatt ccaatttttt
    17461 cgctctatcc tactttgtca gagtggatgg tttattttat catcattttg aacttgagaa
    17521 tgtatcggga tgtttttgcg attcaattga aagttgaagg gaaaaataca ttatttgctt
    17581 gcgatagtat gatttataca tttgttttat ctttagcgag tattgtcttt ctagttcctt
    17641 tttctttagg catttcaggt tattttttcg cttatattgt cagtaatgga atttccattt
    17701 tctttatctt atttttcgga ggagtctgga aaagttttac tagcggaaga tttgaaaaac
    17761 aattgatgat acaactattg aaatattcag cacccatgat tttaaatggt attgcatggt
    17821 ggattacaaa tgcctcagat cggtttatgt tgcaatggtt tatggatgat agagcggtag
    17881 gtttgtatgg tgttgttgca aagttaccct tattaatcgg aacgtttact ggagtattta
    17941 atcaggcatg gattatttca gcagtagaag agtttgaaga agaaaatgaa gaatggtttt
    18001 atcaaaaagt ttttcaccaa tattatgcag cactcttttt aagtgtttca gtatttttgc
    18061 ttctacttca accatttatg aaagtatatg ttagtccaag cttttatgaa gcatggcaat
    18121 atgctccgtt tttattattg tcaagtgtag tttcaggaat cgccgcattt atgacaggtt
    18181 tttatgttgc gcaaaagaaa aatttgaata ttatatacac gacgattgct ggtgcttttg
    18241 cgaatatttt gttaaatgcg atgtttattc ctatgcttgg agtattaggc gcttccattg
    18301 cgacctttct atcatggttt gttattgcaa tctatcgtat gaaagatgtt gaaaactttg
    18361 cttgttttcc attagataaa aaagtttttt ggtatttatt tctattatgt attcagacca
    18421 ttacgatgac ttttctgcca atccttggca ttgttttttc agtcgtattg attccttatt
    18481 tcttttacca agaacaggaa tttctagcag ttttatttga taaaggaagg aaaaaagtat
    18541 gttcattcaa aaaatcaaaa agataataag agtattttta aggaaatctt tagtaaaaga
    18601 ttatcgacaa agaattcaaa ataaagagtt tactcttatt acttctaatt gtgtgggtgg
    18661 actgattagt catgatttgg gtctacaatt tcgttctccc actatcaata tgtatataga
    18721 agcagcagac tttattcagt tttgttcaca tttagaacgc tatttaaaag aagacttatc
    18781 ttttattgaa gtaaatcaag atggacattt tgtagctctt tgtggggata taaaaattta
    18841 tattgttcat tataatagct ttgaagagtt tgctaaaaaa tggtctgaac gtgccaaaag
    18901 agtagatttt gatcaattat atcttatgat gtctgaacga gatggctgtc gttatgaaga
    18961 tattgtgaag tttgatacgt taccctataa gaataaagta atttttacaa gtaaaaagat
    19021 gccagaaatt caatccgctt tttatatacc aggtattgaa acaaaaaata atcaaaaaca
    19081 taaggtgaaa tcagtaacaa cttatcttaa ctcctttaca ggaaaacgat atatagattt
    19141 attcgacttt gtagagtttt tgaatacagg aaggaaacaa ttaagtaagt atgaaaagta
    19201 agataatatt aaaaaataaa acaattcttg ttacaggagc agctggcttt attggtgcta
    19261 atcttgtcat gagtttatta caagaagaaa atccattaca gattattgga atagataatt
    19321 tgaatgatta ttatgatgtt tctttaaaag agtatcgttt atcaacaatt caagaggagt
    19381 gtcaatcatc tttaaataaa aaatgggtat ttatcaaagg agatattgct gattctgatt
    19441 tgatggaaga aatttttgag acgtatagac ctcaaattgt agtgaatttg gcagcacaag
    19501 caggtgttcg ttattctatc actaatcctg atgtttatat gaaaagtaat atcattggat
    19561 ttcatactat tcttgaaaaa tgtagaaagt atcaagaaaa tattgaacat ttagtttatg
    19621 catcatcctc ttctgtttat ggtggaaata caaaaattcc tttttctgaa ttagatgcag
    19681 tagacaatcc tgtttcttta tatgcagtta cgaagaaaac aaatgaatta gaagcacatg
    19741 cgtattcaaa attgtacaat attccaacaa caggcctgag attttttaca gtttatggac
    19801 cagctggaag acctgatatg gcttatttta gttttacaaa gcaattaatt gataaaaagc
    19861 caattgaaat tttcaattat gggaattgtc aacgtgattt tacttatatt gacgatattg
    19921 ttgaaggcgt taaaagagtg atgactggag ctcctcaaaa agaaattgga gaagatgggt
    19981 taccaattcc tccttatgct atctataata ttggaaatca ccaaccagaa aatttattga
    20041 attttgtcga aatcttgcaa gaaaaattga tagctgcttc tattttacca gaagattatg
    20101 atttctcatc tgctcagaaa cttgttccaa tgcaagctgg tgatgtagtt gcaacctatg
    20161 cagatataag tctattggag aaggatttta atttcaaacc taagactagt cttagaaatg
    20221 gcttgagaaa ttttgcagaa tggtatagaa atttttatca aaggggtgaa tagaatgaaa
    20281 attactgtag taggaatggg atatgtcgga ttgtccttgg cggtattatt agcgcaacat
    20341 catgaagtaa cagcgttaga tattattgat aaaaaaattc aactcatcaa tgagaaaaaa
    20401 tctccaattc aagatgagta tattgaacaa tactttttag aaaaaaatct tcatttaagc
    20461 gcaacaacaa acgaagtaga ggcgtataaa gatgcggaaa tgattattat agctgctcct
    20521 acagattatg atacacacaa aaatttcttt gatacatctg ccgtagaaca agtaatcgaa
    20581 aatattattt ctatgaataa cgaggcttta attgtcatta aatcaactgt tcctgttggc
    20641 tatacggagt cgattcgaga aaaatatggt aaaaagaata tactgtttag cccagaattt
    20701 cttcgtgaag caaatggatt gtatgataat ctttatccta atcgaattat cgtaggtaca
    20761 gatttgaatg atggagcatt agtttctaaa gcacatgaat ttgtgtcttt attacaagaa
    20821 ggtgctctca aagagaatat tgatacttta atcatgggat tttctgaagc agaagctgtg
    20881 aaattatttt ccaatgctta tctggcttta agagtgtctt attttaatga gttggatact
    20941 tatgctgaac tgaaaggatt gaatacgaaa gccattattg atggagtagg attggatcct
    21001 agaattggtc agttttataa caatccatcc tttggttatg gtggttactg tttaccaaag
    21061 gatagtaagc aactgttgtc aaattatcat gatgttcctg aaaatattat ttcagcaatt
    21121 gtttctagta atgaaactcg taaaaaattt attgcagaac gtattcttga aatagtcgga
    21181 gctaatcata ttgatgaata ctataatttg aagcaggaaa tcgttgtagg tatttatcgt
    21241 ttagtcatga aaaaaggttc ggataatttt agacattctt ctatccaagg aattataaag
    21301 agactaaaag cgaatggagt gacattaatg atctatgaac cttcacttcc agatggacaa
    21361 ttattttttg gaagtgaagt tgttcatgat tttccaaaat ttaaagaaaa aagccacctt
    21421 attgtagcca atcgttttga tgaaacatta atggatgtaa aggataaagt atatacaagg
    21481 gatttgtttg gaagagatta agggagatag gttttgaaca agttctattc ccaaaaaatc
    21541 acaccgttac tatcttcgaa taaattaaaa gcaaagcaag tgattgatag aaaatcggct
    21601 ctttgtcaac tgtagtgggt tgaagtcagc taagctcgag aaaggacaaa ttttgtcctt
    21661 tcttttttga tattcagagc gataaaaatc cgttttttga agttttcaaa gttccgaaaa
    21721 ccaaaggcat tgcgcttgat aagtttgatg agattattgg tcgcttccaa tttggcgttt
    21781 gaatagggta gttgaagggc gttgacgatt ttctctttgt cctttagaaa ggttttaaag
    21841 acagtctgaa aaagaggatg aacctgctta agattgtcct caataagtcc gaaaaatttc
    21901 tctggttcct tattctgaaa gtgaaacagc aagagttgat agagctgata gtgatgtttc
    21961 aagtcttgtg aatagctcaa aagcttgtct aaaatctctt tattggttaa atgcatacga
    22021 aaagtagggc gataaaaatg tttatcgctg agtttacgac tatcctgttg tatgagcttc
    22081 cagtagcgct tgatagcctt gtattcatga gactatcgat ccaattgatt catgatttga
    22141 acacgcacac gactcatagc acgactaaga tgttgtacaa tgtgaaagcg atcaagaacg
    22201 attttagcat tcgggagtga aacagtctgg gagactgttt cagcctgagc ctagaaattt
    22261 gaaagcgagg ctgtttagct aagtcatagt aaggactaaa catatccata gtaataattt
    22321 tgacgcgaca tcggacaact ctatcgtagc gaagaaagtg atttcgaatg atagcttgtg
    22381 ttctaccctc aagaacagtg atgatatcga gcttttcaaa atcttgcgca atgaagctca
    22441 tctccatctc ccgattgaaa cagtcactcc ccggactgtt tcaacgtccc aagacataat
    22501 ctcaggaaga cgcgaaaaat catgtttaaa gtgaaaatca ttgagcttac gaataacagt
    22561 tgaagttgag atggaaagct gatgggcaat atcagtcata gaaatctttt caattaactt
    22621 ttgagcaatc ttttggttga tgatacgagg gatttggtga ttcttcttga cgatagaagt
    22681 ttcagcgacc atcatttttg aacagtgata gcacttgaat cgacgctttc taaggagaat
    22741 tctagtaggc ataccagtcg tttcaagata aggaatttta gaaggttttt gaaagtcata
    22801 tttcttcatt tgacttccgc actcagggca agatggggcg tcgtagtcca gtttggcgat
    22861 gatttccttg tgtgtatcct tattgatgat gtctaaaatc tggatattag ggtctttaat
    22921 gtctagtaat tttgtgataa aatgtaattg ttccatatga atctttctaa tgagttgttt
    22981 gatcgctttt cattatagac cttatgggac tttttttcta cacaaaaata ggctccataa
    23041 tatccatagg gaatttaccc actacaaata ttatagagcc agaaaatcac ctgctttttg
    23101 tatcaatgtt ttttcacaaa atctaaaata taatggattg aatttggaat agaacactat
    23161 ggtttctaaa gcattgttag aaattatagt caattgaaac aagagcagga caaaagagcc
    23221 tcgtaaaagg tattgcaact tggtaatacc tttttgatgt acgacgggca tgtcgtatat
    23281 ctgaggtgta agtcctcggt gggcacctgc taccggtgaa cccaatagcg attcccaagc
    23341 ctgactatcg tgaggtagca gggagaggaa gggatagcga aatcgtggct ctacgaacag
    23401 gaacgtgata gtaaggcgta tatagcggat aaggaggttt caaactctaa agtccaaaaa
    23461 ggtagtcgta acctatatgt gtaaatcacg agagtaattg aattcggact aaggtttgtg
    23521 tgaaaaagat aaatctttct agagtctaaa gactctgcgt cagatttcct attttcactg
    23581 taacctttta acgtcctcat atcttgtata aacgaggaaa gatgtacaac ttatcccgtg
    23641 aggtttcatg ggcgctgaaa gcgtagtaac aacgaatcat gagaagtcag ccgagcccat
    23701 agtagtgagg aaacttctgt agtggaagtg gagcgaaggg gtgaatactc aaacagtctg
    23761 gggagagact gtttgaggtc tgtcgctaga aagagaaaac gacagatcga agtaatccta
    23821 cttcacttgt gtctgtaaaa tgagtggtct gatagaactg gactttgaca cgtaatgact
    23881 agatgaaggt tcaccaatat aagatgtccc tcaggcacca aaacaagaaa ggaatacgca
    23941 catgtcaaaa ctgctagata agatattatc acgcgaaaat atgctggaag cctacaatca
    24001 agtaaaatcc aataaaggct cagctgggat tgatggaatg actatcgaag agatggataa
    24061 ttatctcaga caaaactggc gcttgactaa ggaactgata aaacagagaa aatataagcc
    24121 tcaaccagtt cttaaagttg agatacctaa accagacgga ggcatccgtc aactaggaat
    24181 tccaacagtt atggatagaa tgattcaaca ggccattgtc caagtcatga gccccatttg
    24241 tgaaccccat ttctcagata cgagttatga tttcagacca aataggtcat gtgaaaaagc
    24301 catcatgaag ctcttagaat acttaaatga cggctatgag tggatagtgg atatagacct
    24361 agagaaattt ttcgatacag ttcctcaaga tagattgatg tccttagtac ataacattat
    24421 cgaagacgga gatacggaat ccttgattcg taagtatctt cattcaggtg ttatcattaa
    24481 tggtcaacgt tataaaacac tagttggtac accacaggga ggaaatttat ctcctctctt
    24541 atctaatatc atgcttaatg aattggacaa ggaattagaa aagaggggac ttcgatttgt
    24601 gcgctacgca gatgattgtg tgattacggt cggaagcgag gcagcctcta agcgtgtgat
    24661 gtattcagtc agtcgtttta ttgagaaacg gctaggtttg aaagtaaaca tgaccaagac
    24721 taagattacc agaccaagag agttgaaata tctaggtttt gggttctgga aatcatcaga
    24781 tggttggaaa agccgtccac atcaagatag tgttcggaga tttaagttta aattgaagaa
    24841 actaacacag aggaaatgga gtatagacct aacaagacgt attgagcaac tgaatttgtc
    24901 tattcgagga tggataaact atttctcatt gggaaatatg aaaagtatag tcgccagcat
    24961 agatgagcgc ttgcgtactc gcctacgagt gattatctgg aagcaatgga agaagaaatc
    25021 gagacgatta tggggattgc ttaagttagg agttcctaaa tggatagcag ataaggtatc
    25081 tggctggggc gaccattatc aattagtagc tcagaagtcg gtacttaaac gtgctatatc
    25141 aaaaccagtc ctggaaaaac gtggactggt ttcgtgtttg gattattacc ttgaacgaca
    25201 tgcgttaaaa gttagttgaa ccgccgtatg ccgaacggca cgtacggtgg tgtgagaggg
    25261 gctagagatt atcccctact ctatgtgctt tttgatatga gcccatgttt tctcaatagg
    25321 attgtactca ggtgagtagg gaggaagagg taaaagttta tgcccaaact ctttgcataa
    25381 aagttctagc ttccccattc tatggaatct tgcattatcc ataataataa ccgatggtgt
    25441 ggttaatgtt ggtaagagaa acttctgaaa ccaagcttca aaaaagtcgc tcgtcatcat
    25501 ctcttcgtaa gtcattggag cgattaactc accatttgtt agacctgcaa ccaaagaaat
    25561 cctctgatat cttcttccag atactttgcc tcttcttaac tgacctttta atgagcgact
    25621 atattctcga taaaaataag tatcgaatcc tgtttcatca atctaaacag gtgataggtg
    25681 ctttaaacta ttaaaattct taagaaataa ggctactttt tctgggtctt gttcatagta
    25741 ggtgtggttc tttttttcga gtgtagtcca tagctttgag cgcatagtgg atggtagttg
    25801 gatgacagcc aaattcagaa gctatttcag tcaaataagc gtctggattg tcagtaagat
    25861 agtttttaag tctatctcta tcaacttttc ttggttttgt tccttttact tggtggttta
    25921 gctctcctgt tttctctttt agctttaacc agccataaat agtattacgt gagatttgga
    25981 aaacgtgtga tgcttctgtt atactacctg ttcgctcaca ataagagaga acttttttac
    26041 gaaaatctat tgaatatgcc ataagaagat tataccacat tgtgtactat ttttggttca
    26101 ttttactata atttaaaatt ccctcatcga tttgttcaca ttctattgca atcaactgta
    26161 aatatgcttt tcagaatata tcaaatataa caaatataac aaataactaa aagttctata
    26221 atagactccc tgcgaaacaa aatatggtat agtagttcta tgaatgatga agcaagtaaa
    26281 caactaaccg atgcacgatt taagcgtctt gttggtgttc agcgtaccac ttttgaagag
    26341 atgttagctg tattaaaaac agcttatcaa cttaaacacg caaaaggtgg acgaaaacct
    26401 aaattaagcc tagaagacct tcttatggcc actcttcaat agtgcgagaa tatcgaactt
    26461 atgaagaaat tgcggctgat tttggtattc acgaaagcaa cttaatccgt cggagccaat
    26521 gggttgaagt aactcttgtt caaagtggtt ttacgatttc aagaacttct ctcagttctg
    26581 aggacacggt aatgattgat gcgacagaag taaaaatcaa tcgccctaaa aaaagaatta
    26641 gcgaattatt ctggtaaaaa gaaatgccac gctatgaagt ctcaggcgat tgtcacaagt
    26701 caagggagaa ttgtttcttt ggatatcact gtgaactatt gtcatgatat gaagttgttc
    26761 aaaatgagtt gcagaaatat cggacaagct ggtaaaatct tggccgacag tggttatcaa
    26821 gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagccg
    26881 ctaacagctg aagataaagc ctgtaaccat gcgctatcta aggagagaag caaggttgag
    26941 aacatctttg ccaaagcata gtatattgaa actagaatag tacacctcta cttctaaaac
    27001 attgttagaa atcgatttga ctgccctgat cgattcgtcc tattcttgtt tcattttgat
    27061 ataaaaacgt ttaaaatgtt ttcaacaact tatcgaaatc atcgtaaacg cttcggatta
    27121 cgaatgaatt tgattgctgc tattatcaat catgaactag gattctagtt ttgcaggaag
    27181 tttaatgaag ttagccaccc agccctccta aaaattagat ggttcagcta gctgaaagct
    27241 cttgtaggca taagaaaaca cctctgtgtt atacttgttg ttcaaccaca aacacaagaa
    27301 aggcacagaa atgcaagaca attatactac aaaaggtaaa catttgacaa tcgatagccg
    27361 tcgcttaatc gaaagatgga aaaaagaagg aaaatcaaat agagaaattg cctctctact
    27421 tggaaaagct cctcaaacta tccacactga aatcaagcgt aggacagtcc gaaaatgtct
    27481 tggaaaaggg cgcttcaaag aggtttattc tgccgactat gctcaacagt cttatgaaaa
    27541 taatcgcaag cactcggtca agagatcaag cgtgaccaag gaactaaagg aaaagattct
    27601 ccactatcat aaccaaaaat ttttgcctga aatgatggtt atggctaaag gggttaacgt
    27661 gggaatttca accatttact attggattca tcatggaaaa ttgggattaa gcaaatagga
    27721 tctgctttac cctagaaaag gaaaagcgct taagaaacag gctagcacca actttaaacc
    27781 tgctggtcaa tccatcgaac agcggcctga agctatcaat cttcgcttgg agaatgggca
    27841 ttatgagatt gatacggttc tacttacgag atcgaaaaac tactgcttgc ttgtcttgac
    27901 ggatcgaaag agtagacatc agatcatccg attgattcca aataaaagtg ctgaggtggt
    27961 caatcaggct ctaaaactca tcttaaaaca acacaagatt ctttccatca cggcagataa
    28021 tggaacggaa ttcaatcgct tgtttgatat attttctgag gagcacatct attatgcgca
    28081 cccctatgcc tcttgggaaa ggggaactaa tgagaatcac aacaggctca ttcgtagata
    28141 gttacctaag ggaaccaaga aaatgactcc caaagaagtc gcattcatcg aaaagtggat
    28201 taacaactat cctaaaaaat gcttggacta caagtcaccc agagaagact tctggatggc
    28261 taacttgaac ttgaaattta gctataacaa ataactctta aaattctgaa aattctgttg
    28321 acaactttct gaaaagagtc tataatggag agaaagtttt aaaggagaaa atgatgaaaa
    28381 gttcaaaact atttgccctt gctggcgtga cattattggc ggcgactact ttagctgcat
    28441 gctctggatc aggttcaagc gctaaa
//
