LOCUS       CR931692               22978 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 1982/45 (serotype 28A).
ACCESSION   CR931692
VERSION     CR931692.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22978)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22978)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22978
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="1982/45"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC28A_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC28A_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI34020.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..461
                     /gene="aliB"
                     /locus_tag="SPC28A_0002"
                     /pseudo
     CDS             293..461
                     /gene="aliB"
                     /locus_tag="SPC28A_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(462..977,979..1305))
                     /gene="tnp"
                     /locus_tag="SPC28A_0003"
                     /pseudo
     CDS             complement(join(462..977,979..1305))
                     /gene="tnp"
                     /locus_tag="SPC28A_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(915..977,979..1287))
                     /gene="tnp"
                     /locus_tag="SPC28A_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 6e-23"
                     /pseudo
     gene            1527..2981
                     /gene="wzg"
                     /locus_tag="SPC28A_0004"
     CDS             1527..2981
                     /gene="wzg"
                     /locus_tag="SPC28A_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34023.1"
                     /db_xref="GOA:Q4K030"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K030"
                     /translation="MLIMSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNI
                     LAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGL
                     TNRLNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNT
                     DLTVDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKV
                     EAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPI
                     ADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVH
                     NDQEFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKL
                     TSTEALKNYSTIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTGRMDL
                     PSYAMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1527..1652
                     /gene="wzg"
                     /locus_tag="SPC28A_0004"
                     /note="Signal peptide predicted for SPC1385 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 42 and 43"
     misc_feature    1740..2087
                     /gene="wzg"
                     /locus_tag="SPC28A_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 6.7e-65"
     misc_feature    2265..2708
                     /gene="wzg"
                     /locus_tag="SPC28A_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 8.4e-70"
     gene            2983..3714
                     /gene="wzh"
                     /locus_tag="SPC28A_0005"
     CDS             2983..3714
                     /gene="wzh"
                     /locus_tag="SPC28A_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34024.1"
                     /db_xref="GOA:Q4K029"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K029"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTLYRDIHSALSKILMLGITPVIAHIERYAALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEKDLVHIIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    2986..3594
                     /gene="wzh"
                     /locus_tag="SPC28A_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1.6e-37"
     gene            3720..4415
                     /gene="wzd"
                     /locus_tag="SPC28A_0006"
     CDS             3720..4415
                     /gene="wzd"
                     /locus_tag="SPC28A_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34025.1"
                     /db_xref="GOA:Q4K028"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K028"
                     /translation="MMKEQNMIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNRNQGDSPGLTNQDLQAGSYLVKDYREIILSQDVLEKVATNLKL
                     DMPAKTLASKVQVTVPADTRIVSISVKDKQPEEASRIANSLREAAAEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQI
                     PLLGVVPDLNKMK"
     misc_feature    3720..3836
                     /gene="wzd"
                     /locus_tag="SPC28A_0006"
                     /note="Signal peptide predicted for SPC1387 by SignalP 2.0
                     HMM (Signal peptide probability 0.774) with cleavage site
                     probability 0.498 between residues 39 and 40"
     misc_feature    3741..4157
                     /gene="wzd"
                     /locus_tag="SPC28A_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 2.7e-56"
     misc_feature    4263..4340
                     /gene="wzd"
                     /locus_tag="SPC28A_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4425..5114
                     /gene="wze"
                     /locus_tag="SPC28A_0007"
     CDS             4425..5114
                     /gene="wze"
                     /locus_tag="SPC28A_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34026.1"
                     /db_xref="GOA:Q4K005"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K005"
                     /translation="MPTLEISQAKLDFVKKAEENYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKSMTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEVNRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            5129..6496
                     /gene="wchA"
                     /locus_tag="SPC28A_0008"
     CDS             5129..6496
                     /gene="wchA"
                     /locus_tag="SPC28A_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34027.1"
                     /db_xref="GOA:Q4K026"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K026"
                     /translation="MNGKILRSSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGKL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVIVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     misc_feature    5129..5215
                     /gene="wchA"
                     /locus_tag="SPC28A_0008"
                     /note="Signal peptide predicted for SPC1389 by SignalP 2.0
                     HMM (Signal peptide probability 0.844) with cleavage site
                     probability 0.429 between residues 29 and 30"
     misc_feature    5912..6493
                     /gene="wchA"
                     /locus_tag="SPC28A_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 2.8e-160"
     gene            6527..7699
                     /gene="wchF"
                     /locus_tag="SPC28A_0009"
     CDS             6527..7699
                     /gene="wchF"
                     /locus_tag="SPC28A_0009"
                     /note="member of homology group 15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34028.1"
                     /db_xref="GOA:Q4K025"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q4K025"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKAIQYYVACMR
                     ENSAKSGITEDVFEHNGAICYNVDVPNIGPARAIAYDIAAINRAIEIAKENKDEDPIF
                     YILACRIGPFIHGIKKRIQAIGGALLVNPDGHEWLREKWSLPVRKYWKYSERLMVKHA
                     DLLVCDSKNIEKYIQEDYKQYQPKTTYIAYGTDTTRSILKSSDEKVRSWFKEKNVSEN
                     EYYLVVGRFVPENNYEAMIRGFLASNSKKDFVLITNVEQNKFYNQLLAKTGFDKDPRV
                     KFVGTVYEQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     QSAIYWKKDELSQVIEKVEQFDAKMIDELDRQSNQRIVDFFTWEKIVTDYEKLFKK"
     gene            7696..8967
                     /gene="wciU"
                     /locus_tag="SPC28A_0010"
     CDS             7696..8967
                     /gene="wciU"
                     /locus_tag="SPC28A_0010"
                     /note="member of homology group 59"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34029.1"
                     /db_xref="GOA:Q4K024"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K024"
                     /translation="MKILHYTLGFQPQRTGGLVKYAEDLMIEQIAQGYQVAALCPGRI
                     KFFSKKIEIIKATSRQFECYELLNSLPIALFGGISDPTAFMTPCDKNVYRTFLEKVQP
                     DIIHIHSFMGLHKEFLEIAKNLNIRVVFTSHDYYGLAPVPHFYFNGVDYSDKNTNLTW
                     NIMSSNALSVKKLRLFQVSFYPTIRKLLKLLGKNPKSKKNLVIRDVIEEQDYSELRYY
                     YNEMFHLIDGYLFNSRLAKKVYEINEIQPVNSVVLSITSSSIKHHQRLTTTNNKIRVA
                     YIGSDEEYKGYFDFIDFAGTLEQESYEVVTYGHLPNEECPSFIEQKGYFTKETIDSVY
                     ENIDILIIASKCKETFGLITVEALSYGVNVFVSENVGSKDLLPETHVFKNQNDLVVKF
                     LKNDIENTKLKTLDEHSIEVIQYYERVINDS"
     misc_feature    8470..8931
                     /gene="wciU"
                     /locus_tag="SPC28A_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 0.00061"
     gene            8957..9643
                     /gene="wcxM"
                     /locus_tag="SPC28A_0011"
     CDS             8957..9643
                     /gene="wcxM"
                     /locus_tag="SPC28A_0011"
                     /note="member of homology group 105"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI34030.1"
                     /db_xref="GOA:Q4K001"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="UniProtKB/TrEMBL:Q4K001"
                     /translation="MIVKSFIKKITGKTVDIHPDVPLSYILQRGINYGFGLFRGVVRG
                     IGFGQNDKRLFIGQGVSILAKRKLFVGKNVRIGKKVSIDALSKEGIHFADNVKIGDYS
                     QIIGTGSIKNMGIGLKIGKNSSFSEYSLFGSAGGITIGDNVIAGQNVRFHAENHNYSD
                     LDKLIVEQGVSRKGISVGDNCWIGAGSVFLDGSSIGSGCVVAANSVITKNFPDNVIVA
                     GVPAKIIKMK"
     misc_feature    9155..9208
                     /gene="wcxM"
                     /locus_tag="SPC28A_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 16"
     misc_feature    9221..9274
                     /gene="wcxM"
                     /locus_tag="SPC28A_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 13"
     misc_feature    9362..9415
                     /gene="wcxM"
                     /locus_tag="SPC28A_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 10"
     misc_feature    9476..9529
                     /gene="wcxM"
                     /locus_tag="SPC28A_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 11"
     misc_feature    9530..9583
                     /gene="wcxM"
                     /locus_tag="SPC28A_0011"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 1.7"
     gene            9655..10533
                     /gene="wcxN"
                     /locus_tag="SPC28A_0012"
     CDS             9655..10533
                     /gene="wcxN"
                     /locus_tag="SPC28A_0012"
                     /note="member of homology group 154"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34031.1"
                     /db_xref="GOA:Q4K000"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K000"
                     /translation="MGKEIKAVYAILNYNTWEDTARLAQKVATFQHIQSVIIVDNLST
                     DDSYHYLKRLEGEKISVYQTQRNGGYSVGNNVAARKAYNMGVDILFISNPDVDIDEKD
                     SLMIAQNLYKNSSYALLSGIEYNAMKEIDLPIVWHENSYYDDLLDCLFLTRKLRRKKE
                     DINLSMIKSSIIDVDLVKGSFFAVRLSDFHDVGYFDESVFLFCEERILAKKLQKANKK
                     IGILPEAKYYHNHSTSINEKYKKKKEQIVLLYNARYYYNVTYQNISFLKKICLKLFMF
                     LSIIEYSILDYIKRKG"
     gene            10542..11774
                     /gene="wzy"
                     /locus_tag="SPC28A_0013"
     CDS             10542..11774
                     /gene="wzy"
                     /locus_tag="SPC28A_0013"
                     /note="member of homology group 251"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase Wzy"
                     /protein_id="CAI34032.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q4K021"
                     /translation="MVINFSKYNWILILILSSSELFSKETNLFLLLFILLYYVLVRGG
                     RLPISIPGAKYYFTLLMVGLFIGIGNVIINENTVFNFVKHFIYYLLPLFFWQFGCVLS
                     NNDNLSYKQNNIKESIVITAFLLSSYDLIGSIISFLSRTKEIVDLYSLRSEFGRGSYI
                     PIIALYLVLVYSREIKLSKNFKGFLLLLFTISILIHFSRTHFIILLILVFFSGFEKNM
                     KSIKKIMFAGTLILAGVGVLYLYFPNLVIDFYNKISQSTTEITFSKSSWSHKDIIWNW
                     RGYEMYSALNHFKSSTLLEQILGGGFGTVLYIGEYAYFVSDLPYLLFLHNGYFTTLLV
                     FGVSGVILFVLWVLSLFSYSKYVNDTQDSNFIKGLAVVILFTTYFVNGPLFSVSQATF
                     LLYFALFSNNHGELDEDF"
     gene            11761..12921
                     /gene="wcxP"
                     /locus_tag="SPC28A_0014"
     CDS             11761..12921
                     /gene="wcxP"
                     /locus_tag="SPC28A_0014"
                     /note="member of homology group 155"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol phosphotransferase"
                     /protein_id="CAI34033.1"
                     /db_xref="GOA:Q4JZZ8"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="UniProtKB/TrEMBL:Q4JZZ8"
                     /translation="MKIFKKIKFILMLLYTSTFPRCEKILIFGSWLGEKYADNPRYLF
                     EYVIKNRPDLKAIWITSNQDVFKELQKKQYPVMMADESEAHKIMKKAKYIFTTTGIFD
                     IGVENSRLIGGAFLINLWHGIPLKKIMYDDKHSALHKRSKLVTWVEKIPLRNYFVIST
                     STAITQIYQSAFRVKKSNILELGQPRNDYFYDESYPVSSLIQELKSKNIILYMPTHRN
                     EGKKQIPLDNLMDLNRLNKWCEETNSIFVIKKHFYHSKEKTLEKEYSSIIDVTNEKVD
                     AQELLKYSKILITDYSSCYIDYLLLDRPIIFFNYDYDDYLRIDRSLYFPYEKVTPGEK
                     CQNFDELLVTLQNLYLGKDDYRKKRENIKTFFYSSETQKSVSEKIINHVLNL"
     misc_feature    12349..12915
                     /gene="wcxP"
                     /locus_tag="SPC28A_0014"
                     /note="HMMPfam hit to PF04464,
                     CDP-Glycerol:Poly(glycerophosphate) gl, score 4.5e-32"
     gene            12927..14378
                     /gene="wzx"
                     /locus_tag="SPC28A_0015"
     CDS             12927..14378
                     /gene="wzx"
                     /locus_tag="SPC28A_0015"
                     /note="member of homology group 52"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase Wzx"
                     /protein_id="CAI34034.1"
                     /db_xref="GOA:Q4JZZ7"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JZZ7"
                     /translation="MESVMKKILNKYYSLSNPVKASIWFTICNVLQKGISMITVPIFT
                     RLLTTEQYGVYSVYQSWYSIIGVFATLNLYYGVFNNGMVKYEKDKNAFTSSMQGLTTT
                     VTAIFLVIYLIGIDFWNSLLGLPTLLILVMFFDLFFTPAYSFWATRQRFEYQYRNLVF
                     ITLIIAIGSPIIGISSVVLSTYKAEARVISFVLVQSCIGLYFYVLNLYRGKYFFCKKY
                     WLYALNFNLPLIPHYLSQSVLNQSDRIMINSMVGMGEAAIYSVAYSISTLMVLVTSAI
                     NSSFIPYTYKCIRDKKYTELGKSANLLITLVGIGSILTISLGPEIIQLFAPKQYYEAI
                     WIIPPVALSVYFMFLYPIFGNIEFYFEANHFVMWASIGGAIMNIFLNFIFIKHFGYIA
                     AGYTTLLCYILFALGHYIFMRRALYQNLSGIQIYDSRYIFFFSFLLLILMLLIVTIYP
                     FVLIRYIAISLILGGCFLKRRKIMSSIVMIKKQ"
     misc_feature    12978..13790
                     /gene="wzx"
                     /locus_tag="SPC28A_0015"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.9e-12"
     gene            14388..15200
                     /gene="wcxQ"
                     /locus_tag="SPC28A_0016"
     CDS             14388..15200
                     /gene="wcxQ"
                     /locus_tag="SPC28A_0016"
                     /note="member of homology group 156"
                     /codon_start=1
                     /transl_table=11
                     /product="putative LicD-family phosphotransferase"
                     /protein_id="CAI34035.1"
                     /db_xref="GOA:Q4JZZ6"
                     /db_xref="InterPro:IPR007074"
                     /db_xref="UniProtKB/TrEMBL:Q4JZZ6"
                     /translation="MTEINKQLHETLIEILDFVKEICEKHELTYFLIYGTALGAKRHC
                     GFIPWDDDVDIALPREHYNILIDVLSKMEQSIFSLQNEDNEPNYFLPFAKLRKNNTIF
                     IEKILDVEYENNGIYIDIFPLDFVENPDSFNFKMRRTMFNYIKHILKFSSCRSFYKNK
                     YSSVRYLMENIMSIPTLFFSNRRLLFLANNLISSTNKANFIGQYDESSERAIMPSSYY
                     FPSRSAVFEGKIYSVPAKLEDYLKYFYGSDYMELPPIEKRVTHQPIKLRFKK"
     misc_feature    14454..15125
                     /gene="wcxQ"
                     /locus_tag="SPC28A_0016"
                     /note="HMMPfam hit to PF04991, LICD Protein Family, score
                     1.4e-36"
     gene            15276..16304
                     /gene="gtp1"
                     /locus_tag="SPC28A_0017"
     CDS             15276..16304
                     /gene="gtp1"
                     /locus_tag="SPC28A_0017"
                     /note="member of homology group 40"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol-2-phosphate dehydrogenase"
                     /protein_id="CAI34036.1"
                     /db_xref="GOA:Q9R921"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="InterPro:IPR016205"
                     /db_xref="UniProtKB/TrEMBL:Q9R921"
                     /translation="MKNNDLKIGSGAIHQISATLSQNSISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     misc_feature    15297..16217
                     /gene="gtp1"
                     /locus_tag="SPC28A_0017"
                     /note="HMMPfam hit to PF01761, 3-dehydroquinate synthase,
                     score 2.9e-70"
     gene            16320..17024
                     /gene="gtp2"
                     /locus_tag="SPC28A_0018"
     CDS             16320..17024
                     /gene="gtp2"
                     /locus_tag="SPC28A_0018"
                     /note="member of homology group 41"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotidyl transferase"
                     /protein_id="CAI34037.1"
                     /db_xref="GOA:O85005"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="UniProtKB/TrEMBL:O85005"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     misc_feature    16323..17021
                     /gene="gtp2"
                     /locus_tag="SPC28A_0018"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 1e-07"
     gene            17021..17872
                     /gene="gtp3"
                     /locus_tag="SPC28A_0019"
     CDS             17021..17872
                     /gene="gtp3"
                     /locus_tag="SPC28A_0019"
                     /note="member of homology group 42"
                     /codon_start=1
                     /transl_table=11
                     /product="putative phosphotransferase"
                     /protein_id="CAI34038.1"
                     /db_xref="GOA:Q4K015"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006357"
                     /db_xref="UniProtKB/TrEMBL:Q4K015"
                     /translation="MNRIRRMKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLF
                     EGTLELLDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYI
                     KENYPKSKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEI
                     LSTKDVPFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRK
                     KLNYSLFETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQDSIKPTYTFKNVK
                     EMWKGIV"
     misc_feature    17096..17782
                     /gene="gtp3"
                     /locus_tag="SPC28A_0019"
                     /note="HMMPfam hit to PF00702, haloacid dehalogenase-like
                     hydrolase, score 5.9e-25"
     gene            18032..18901
                     /gene="rmlA"
                     /locus_tag="SPC28A_0020"
     CDS             18032..18901
                     /gene="rmlA"
                     /locus_tag="SPC28A_0020"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI34039.1"
                     /db_xref="GOA:Q4JZZ2"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4JZZ2"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    18035..18751
                     /gene="rmlA"
                     /locus_tag="SPC28A_0020"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 3.2e-120"
     gene            18902..19495
                     /gene="rmlC"
                     /locus_tag="SPC28A_0021"
     CDS             18902..19495
                     /gene="rmlC"
                     /locus_tag="SPC28A_0021"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI34040.1"
                     /db_xref="GOA:Q4K013"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q4K013"
                     /translation="MTDNFFGKTLAARKVETIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKYHPLLKDVKPLKKEDL"
     misc_feature    18938..19468
                     /gene="rmlC"
                     /locus_tag="SPC28A_0021"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 1.3e-15"
     gene            19508..20557
                     /gene="rmlB"
                     /locus_tag="SPC28A_0022"
     CDS             19508..20557
                     /gene="rmlB"
                     /locus_tag="SPC28A_0022"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI34041.1"
                     /db_xref="GOA:Q4K2P4"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K2P4"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    19523..20479
                     /gene="rmlB"
                     /locus_tag="SPC28A_0022"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.0001"
     misc_feature    19526..20266
                     /gene="rmlB"
                     /locus_tag="SPC28A_0022"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 2.7e-76"
     misc_feature    19529..20341
                     /gene="rmlB"
                     /locus_tag="SPC28A_0022"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/iso, score 1.7e-05"
     gene            20623..21474
                     /gene="rmlD"
                     /locus_tag="SPC28A_0023"
     CDS             20623..21474
                     /gene="rmlD"
                     /locus_tag="SPC28A_0023"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI34042.1"
                     /db_xref="GOA:Q4K011"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K011"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDIIDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    20623..21471
                     /gene="rmlD"
                     /locus_tag="SPC28A_0023"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 3.3e-146"
     misc_feature    20626..21255
                     /gene="rmlD"
                     /locus_tag="SPC28A_0023"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 8.4e-17"
     misc_feature    20626..21267
                     /gene="rmlD"
                     /locus_tag="SPC28A_0023"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00014"
     misc_feature    20629..21357
                     /gene="rmlD"
                     /locus_tag="SPC28A_0023"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 3.2e-08"
     gene            order(21550..22506,22514..22735)
                     /gene="tnp"
                     /locus_tag="SPC28A_0024"
                     /pseudo
     CDS             join(21550..22506,22514..22735)
                     /gene="tnp"
                     /locus_tag="SPC28A_0024"
                     /note="member of homology group 12; member of homology
                     group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     misc_feature    21556..21999
                     /gene="tnp"
                     /locus_tag="SPC28A_0024"
                     /note="HMMPfam hit to PF03050, Transposase IS66 family,
                     score 0.00014"
                     /pseudo
     gene            22931..>22978
                     /gene="aliA"
                     /locus_tag="SPC28A_0025"
     CDS             22931..>22978
                     /gene="aliA"
                     /locus_tag="SPC28A_0025"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34044.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K2C2"
                     /translation="MMKSSRLLALAGVTLL"
BASE COUNT     7468 a   3484 c   4627 g   7399 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attctcgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga aaatgaacat
      301 aaagaagcgt gtccttagtg caggtctgac ttttgcatct gctttgcttt tagctgcttg
      361 cgaccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaattac ctgttagact attacgctga taatatagtc aattgaaaca agagcaggac
      481 aaaagagcct cgtaaaaggt attgcaactt ggtaatacct tttacgaggc tttttgatat
      541 gagcccatgt tttctcaata ggattgtact caggtgagta gggaggaaga aggtaaaagt
      601 ttatgcccaa actcttcgca taaaagttct agcttcccca ttctatggaa tcttgcatta
      661 tccataataa taaccgatgg tgtggttaat gttggtaaga gaaacttctg aaaccaagct
      721 tcaaaaaagt cgctcgtaat cgtctcttcg taagtcattg gagcgattaa ctcaccattt
      781 gttagacctg caaccaaaga aatcctctga tatcttcttc ttaactgacc ttttaaagag
      841 cgaccatatt ctcgataaaa ataagtatca aatcctgttt cgtcaatcta aacagctgct
      901 aggtgcttta aactattaaa attcttaaga aataaggcta ctttttctgg gtcttgttca
      961 tagtaggtgt ggttcttttt ttcgagtgta gcccatagct ttgagcgcat agtggatggt
     1021 agttggatga cagccaaatt cagaagctat ttcagtcaaa taagcgtctg gattatcagt
     1081 aagatagttt ttaagtctat ctctatcaac ttttcttggt tttattcctt ttacttggtg
     1141 gtttagctct cctgttttct cttttagctt taaccagcca taaatggtat tacgtgagat
     1201 ttggaaaacg tgtgatgctt ctgttatact acctgttcgc tcacaataag agagaacttt
     1261 tttacgaaaa tctattgaat atgccataaa aagattatac cacattgtgt actatattag
     1321 attgaaacta gagtagtaca cctctgcttc taaaaaattt ttagaaatcg atttaactgt
     1381 cctgatcgat ttgtcatgtt cttatttcat tttactatat ttttgtttcg cgggaagtct
     1441 actaagatac ttaaagatgc agatagtaaa aaaatgtaga cattaccgta aaaaagtgat
     1501 ataattgtac gatgttcaag gtataggtgt taatcatgag tagacgtttt aaaaaatcac
     1561 gttcacagaa agtgaagcga agtgttaata tcgttttgct gactatttat ttattgttag
     1621 tttgtttttt attgttctta atctttaagt acaatatcct tgcttttaga tatcttaacc
     1681 tagtggtaac tgcgttagtc ctactagttg ccttggtagg gctactcttg attatctata
     1741 aaaaagctga aaagtttact atttttctgt tggtgttctc tatccttgtc agctctgtgt
     1801 cgctctttgc agtacagcag tttgttggac tgaccaatcg tttaaatgcg acttctaatt
     1861 actcagaata ttcaatcagt gtcgctgttt tagcagatag tgatatcgaa aatgttacgc
     1921 aactgacgag tgtgacagca ccgactggga ctgataatga aaatattcaa aaactactag
     1981 ctgatattaa gtcaagtcag aataccgatt tgacggtcga ccagagttcg tcttacttgg
     2041 cagcttacaa gagtttgatt gcaggggaga ctaaggccat tgtcttaaat agtgtctttg
     2101 aaaatatcat cgagtcagag tatccagact acgcatcgaa gataaaaaag atttatacca
     2161 agggattcac taaaaaagta gaagctccta agacgtctaa gaatcagtct ttcaatatct
     2221 atgttagtgg aattgacacc tatggtccta ttagttcggt gtcgcgatca gatgtcaata
     2281 tcctgatgac tgtcaatcga gataccaaga aaatcctctt gactacaaca ccacgtgatg
     2341 cctatgtacc aatcgcagat ggtggaaata atcaaaaaga taaattaacc catgcgggca
     2401 tttatggagt tgattcgtcc attcataccc tagagaacct ttatggtgta gatattaatt
     2461 attatgttcg tttgaatttt acctcatttt tgaaattgat tgacttattg ggaggggtag
     2521 atgttcataa tgatcaagag ttttcagctc tacatgggaa gttccatttc ccagtaggga
     2581 atgtccatct agactctgag caagctttag gttttgttcg tgagcgctac tccctagcag
     2641 atggcgatcg tgaccgtggt cgcaaccaac aaaaggtgat tgtggctatc cttcaaaaat
     2701 taacgtcaac cgaagcactg aaaaattata gtacgatcat tgatagcttg caagattcta
     2761 tccaaacaaa tatgccactt gagaccatga taaatttggt caatgctcag ttagaaagtg
     2821 gtggaactta caaagtgaat tcgcaagact tgaaaggtac aggtcggatg gatcttcctt
     2881 cttatgcaat gccagacagt aacctctatg tgatggaaat agatgatagt agtttagctg
     2941 tagttaaagc agctatacag gatgtgatgg aggggagatg aaatgataga catccattca
     3001 catatcgttt ttgatgtaga tgacggtccc aagtcaagag aggaaagcaa ggctctcttg
     3061 gcagaagcct acagacaggg ggtgagaacc attgtctcta cctctcaccg tcgcaagggc
     3121 atgtttgaaa ctccggaaga gaagatagca gaaaactttc ttcaggttcg ggaaatagct
     3181 aaggaagtgg cgagtgactt agtcattgct tacggagctg aaatttacta cacaccagat
     3241 gttctggata agctgggaaa aaagcggatt ccgaccctca atgatagtcg ttatgccttg
     3301 atagagttta gtatgaacac tctttatcgc gatattcata gcgccttgag caagatcttg
     3361 atgttgggaa ttactccagt cattgcccac atcgaacgct atgctgctct tgaaaataat
     3421 gaaaaacgcg ttcgggagct gattgatatg ggctgttaca cgcaagtaaa tagttcacat
     3481 gtcctcaaac ccaaactttt tggcgaacgt tataaattca tgaaaaaaag agctcagtat
     3541 tttttagaga aagatttggt tcatatcatt gcaagtgata tgcacaatct agacggtaga
     3601 cctcctcata tggcagaagc atatgacctt gttacccaaa aatacggaga agcgaaggct
     3661 caggaacttt ttatagataa tcctcgaaaa attgtaatgg atcaactaat ttaggagaaa
     3721 tgatgaaaga acaaaacatg atagaaatcg atgtatttca attatttaaa accttgtgga
     3781 aacgcaagct aatgatttta ttagtggcac ttgtgacagg tgcgggggct tttgcatata
     3841 gcacttttat tgttaagcca gaatatacga gtaccacgcg aatttacgta gtgaatcgca
     3901 atcaaggaga cagtccgggg ctgacaaatc aggatttgca ggcaggatct tatctggtaa
     3961 aagactaccg tgagattatc ctttcgcagg atgtattgga aaaagtagcg acaaatttga
     4021 agctggatat gccagccaaa acgttagcca gcaaagttca agtgactgta ccagctgaca
     4081 ctcgtatcgt ctcaatctct gtcaaggata aacagccaga ggaagccagt cgtatcgcta
     4141 attctctacg agaagctgct gcagaaaaga tcgtcgctgt aacgcgagta tctgatgtaa
     4201 cgacacttga agaagcgcga ccagctacga ctccctcttc tccaaatgtt cgacgcaatt
     4261 ccttgtttgg ttttcttgga ggagcagtcg taacagtaat tgctgttctt ttgattgagt
     4321 tgctcgacac ccgtgtgaaa cgtcctgaag atgtcgaaga tgtactgcaa attccacttt
     4381 taggggtcgt tccagatttg aacaaaatga aataggagga agttatgcca acattagaaa
     4441 tctcacaggc aaaattggat tttgtaaaaa aggcagagga aaattataac gctttgtgca
     4501 cgaacctaca gttaagtgga gatgatttga aagtattttc tatcacttct gtgaaagcag
     4561 gagaaggaaa atcaatgact tccaccaata tcgcttgggc ttttgcgcat gcaggttaca
     4621 aaacgctgct gattgatgga gatattcgca attctgttat gttaggtgtc tttaaagcaa
     4681 gggataagat tacaggcctg acagaatttt tatcaggaac tacagaccta tcacaagggc
     4741 tttgtgatac caatatcgaa aatctctttg taattcaggc tggctctgtg tcaccgaatc
     4801 cgacagctct tcttcaaagt aagaatttca gtacaatgct tgaaaccttg cgtaaatatt
     4861 ttgactacat cattgtagat actgctcctg tcggtgtcgt gattgatgcg gctattatta
     4921 cgcgaaaatg cgatgcttct attttagtga cggaggcagg tgaagtaaat cgtcgggata
     4981 ttcaaaaagc aaaagaacag ttggaacaca caggaaagcc gtttttggga attgtgttga
     5041 ataaattcga tacttcagta gacaaatacg gttcttatgg aaattatgga gattacggga
     5101 aaaataaaaa ataggtcggg ggatagagat gaatggaaaa atattaaggt cttcattggc
     5161 cataatccag agttttcttg ttattttatt gacttatcta cttagtgctg tgagagaaac
     5221 ggagattgtt tcaacaacag ctattgcact ttatatcctc cattattttg tcttttatat
     5281 cagtgattat ggacaggatt tctttaaaag gagatatttg attgaacttg tccagacatt
     5341 gaaatatatc ctattctttg cactagcgat tagtatttct aattttttct tagaggatcg
     5401 atttagtatt tccagacgag gcatgattta cttcctcaca ttacatgctc tcttagtcta
     5461 tgtgctaaac ctatttatca agtggtattg gaagcgggct tatcccaact ttaaaggaag
     5521 taagaagatt ctcctactta cagcaacttc tcgtgtcgaa aaggtactgg atagattaat
     5581 agaatcaaat gaggttgttg ggaagttggt agccgtcagt gtcttagata aaccagattt
     5641 tcagcatgat tgtttaaagg tagtagcaga gggggagata gtaaactttg cgactcatga
     5701 ggtggtcgat gaagtcttta tcaatcttcc aagtgaaaaa tacaatattg gagagcttgt
     5761 ctctcagttt gaaacgatgg gaattgatgt aatagtcaat ctaaatgctt ttgatcgtag
     5821 tttggcacgt aacaagcaaa ttcgtgagat ggcagggtta aacgttgtga ctttttctac
     5881 aacattttat aagactagtc atgtaattgc taagcggatt attgatatcg tgggtgcatt
     5941 ggtagggctg atactatgtg gtttagtcag tattgtactg gttcctttga ttcgaaagga
     6001 tgggggatct gctatttttg ctcagacgcg tataggaaaa aatggtcgtc agttcacttt
     6061 ttataagttt cgctctatgt gtgtagatgc cgaggcgaaa aaaagagaac ttatggaaca
     6121 aaataccatg caaggtggaa tgtttaaggt ggacgatgat cctcgtatca cgaaaattgg
     6181 ttgttttata cggaagacta gcttggacga gctaccacag ttttataatg ttctaaaggg
     6241 agatatgagt ttggttggca cacggccacc aacagtggac gagtatgagc actatacccc
     6301 agaacaaaaa cgccgactaa gttttaaacc tggcataaca ggtttatggc aggtcagcgg
     6361 acgaagtgag atcaagaatt tcgatgaagt tgtcaaatta gatgtagcct atatagacga
     6421 ttggacaatt tggaaagata ttgagatttt attgaagaca gttaaagttg tattgatgaa
     6481 ggatggagcg aagtaatttc tgtatatcca tcatattagg agagaaatga aaaagtcagt
     6541 ttatatcatt ggttcaaaag gaattcctgc taagtatgga ggatttgaaa cttttgttga
     6601 aaaattaaca gccttccaac aagataaggc tatccaatat tatgtggctt gtatgcgtga
     6661 aaattctgca aaatcaggga ttactgagga tgtttttgaa cataatggtg ctatctgtta
     6721 taacgtcgat gttcctaata ttggtccagc gcgagctata gcgtatgata tcgctgcaat
     6781 taacagagct attgaaattg ccaaagaaaa taaggatgaa gatccaatct tctatatttt
     6841 agcttgtcga attggtccgt ttatccatgg aattaagaaa agaattcaag caataggtgg
     6901 ggctcttctg gttaatccgg atggtcatga atggctacga gaaaaatgga gtttacctgt
     6961 tcgcaaatat tggaaatact ctgaaagact tatggtcaaa catgcagatc ttttagtgtg
     7021 tgatagtaag aatattgaaa aatatatcca agaagattat aaacagtatc aacctaagac
     7081 aacctatatc gcttatggga ctgatacaac acgctccata ttaaagagta gtgacgaaaa
     7141 agtacgttct tggttcaaag agaagaatgt ttctgaaaac gagtattacc tagttgtagg
     7201 acgttttgtt ccagaaaata actatgaggc tatgatacgt gggtttttag catctaattc
     7261 taagaaggac tttgtcttaa tcacaaatgt agaacagaat aaattttata atcagttgtt
     7321 ggcaaaaact ggttttgata aggacccacg agtaaaattt gtaggtacag tctatgagca
     7381 agagcttctt aaatatattc gtgaaaacgc ctttgcttac ttccacgggc atgaagttgg
     7441 tggaaccaat ccttcgcttt tagaagctct ggcatcaact aaactgaatt tattgctaga
     7501 tgttggcttt aaccgagaag ttggggagca aagtgcaatc tattggaaaa aagatgagct
     7561 ttcccaagta atcgagaaag ttgaacaatt tgatgcaaaa atgattgatg agttagatag
     7621 acaatcaaat cagagaattg tggatttttt cacttgggaa aagattgtca cagactacga
     7681 gaaattattt aaaaaatgaa aatattacat tatactttag gatttcaacc ccagcgaaca
     7741 ggtggtttgg ttaaatatgc tgaggattta atgatagagc aaattgctca aggttatcaa
     7801 gtagccgccc tatgtccagg gagaattaag ttcttttcaa aaaaaataga aataattaaa
     7861 gcgacgtcaa ggcagtttga gtgttatgaa ctgcttaata gcttacctat agctttattt
     7921 ggaggtatat ccgatccaac tgctttcatg acaccttgtg acaaaaatgt ttatcgtact
     7981 tttttagaaa aagtacaacc cgacattata catattcact cgtttatggg attgcataaa
     8041 gaattcctcg aaattgctaa aaacttgaat attagagtgg tttttacgag ccatgattat
     8101 tatggattag cacccgtacc tcatttctat tttaatgggg tggattatag tgataaaaat
     8161 acaaacttaa catggaatat tatgtcttcc aatgctttaa gtgtgaaaaa actaagactt
     8221 tttcaagttt cattttatcc tactattcgt aaacttttga aactattagg gaaaaatcca
     8281 aaatctaaaa agaatttagt tattcgagat gttattgagg aacaagatta tagtgaactt
     8341 cgatactatt ataatgagat gtttcactta atagatggtt atttgtttaa tagtagactt
     8401 gcaaagaagg tatatgagat aaacgagatt caaccagtta atagtgtagt attatctata
     8461 acaagtagtt caattaaaca tcatcagaga ttaacgacta caaataataa gattagggtt
     8521 gcttatattg gttcagacga agaatataaa ggttactttg attttattga ctttgctgga
     8581 actttagaac aagaatcata tgaagtggta acttatggtc atttaccaaa tgaagagtgc
     8641 ccttcattca ttgaacaaaa aggatatttt accaaggaaa cgattgacag tgtctatgaa
     8701 aatattgata ttttgattat agcaagcaaa tgtaaagaaa cctttggatt gataacagta
     8761 gaagcattat cctatggggt aaatgttttt gtgagtgaaa atgttggatc aaaagacttg
     8821 cttccagaaa cacatgtttt taaaaatcag aatgatttag tagttaaatt tttaaaaaat
     8881 gatatagaaa atacaaaatt gaaaacttta gatgaacact cgatagaagt gattcagtat
     8941 tatgaaagag tgataaatga tagttaagag tttcataaaa aagattactg gaaaaacagt
     9001 agacattcat ccagatgtac ctttgtcgta tatactacaa agaggtataa actatggttt
     9061 cggactcttt cgtggggttg tacgtggaat cggatttggt caaaacgaca aacgtttatt
     9121 cattggacaa ggagtttcta tcttagcaaa gcgtaaatta tttgttggaa aaaatgttcg
     9181 aattggtaaa aaggtgtcta tagatgcact gtcaaaagaa ggaatccatt ttgcagataa
     9241 tgtaaagatt ggagattatt ctcaaattat tggcacaggt tctataaaaa atatggggat
     9301 tggcttgaaa atcggtaaga actcatcttt ttcagaatat agtttatttg gttctgctgg
     9361 aggtatcaca attggtgata atgttatcgc aggtcagaat gttcgttttc atgctgaaaa
     9421 tcataattat agtgatttag ataaactcat tgttgaacaa ggggtatctc gaaagggaat
     9481 ttcagtaggt gataattgtt ggattggtgc tggatctgtt tttttggatg ggtccagcat
     9541 tggttcaggt tgtgttgtag ctgcaaattc tgtaattacg aaaaactttc cagataacgt
     9601 tattgttgct ggagtaccag ctaaaattat aaaaatgaaa tgataggatg ttaaatgggg
     9661 aaagaaatta aagctgttta tgcgatatta aattacaata cttgggaaga tactgcgcgt
     9721 ttagcacaga aagttgcaac atttcagcat attcaatctg tgataatagt ggataatcta
     9781 tcaacagatg attcatacca ttatttaaaa agacttgagg gagagaaaat ttcagtttat
     9841 caaacacaaa gaaatggtgg atattctgtt ggaaataatg ttgcagcacg aaaagcttat
     9901 aatatgggag ttgatattct tttcatttca aatccagacg ttgatattga tgaaaaagat
     9961 tccttgatga ttgcacaaaa tttgtataaa aatagttcat atgcactgct atcaggtata
    10021 gaatataatg ctatgaagga gatagatttg ccaattgtct ggcatgaaaa ttcctattac
    10081 gatgacttac ttgattgttt gtttttaacc agaaaattgc gaagaaaaaa agaagatatc
    10141 aatttgtcaa tgattaaatc atctataata gatgtagatc ttgttaaagg ctcgtttttt
    10201 gctgtaaggc tgtctgattt tcatgatgtt ggttattttg atgaatctgt atttcttttt
    10261 tgtgaagaga gaatattagc caaaaagtta caaaaagcaa ataaaaaaat aggtattctg
    10321 cctgaagcga aatattacca caatcattca acttctataa acgagaagta taaaaagaaa
    10381 aaagaacaga tagttttact atataatgct cgttattatt acaatgtgac gtatcaaaat
    10441 attagctttt tgaaaaaaat ttgcctaaaa ctattcatgt ttttatctat tattgaatac
    10501 tcgatactag attatattaa acgaaaggga tagttatttt tatggttatt aactttagta
    10561 aatataattg gattttaatt ttaattttat cgagctcaga actgttttct aaagaaacaa
    10621 atctattttt attactattt attctactat actatgtttt agttcgtgga ggtagactac
    10681 caatttcaat tccaggagcg aaatattatt ttactttatt aatggtgggg ctatttatag
    10741 gtattgggaa tgtaataatt aacgaaaata cagtatttaa ttttgtaaag cattttatct
    10801 attacttatt acctctattt ttttggcagt ttggatgtgt tctgtcaaat aacgataatt
    10861 tatcttacaa gcaaaacaat attaaggaat caattgttat aacagcattt ctattatctt
    10921 cttatgattt aataggttca atcattagtt tcttgtctag aactaaggaa attgttgatt
    10981 tatatagttt acggtcagag tttggtcgag gttcctatat accaattatt gcactgtatt
    11041 tagttcttgt ttattctaga gaaataaagt tgagcaaaaa ttttaaggga tttttgttat
    11101 tactgtttac aatctcgatt ttgatacatt tttctaggac acattttatt attttattga
    11161 ttctagtatt tttttcagga tttgaaaaaa atatgaaaag tattaaaaaa ataatgtttg
    11221 caggaacatt gatattagca ggtgtaggtg ttttatattt atattttcca aatttagtta
    11281 tagattttta taataaaata tctcaatcaa cgacggaaat cacgttttct aaatcgtcat
    11341 ggtcccataa agatatcata tggaattggc gtggatatga aatgtactct gccttaaatc
    11401 attttaaatc ttcaacttta ttagagcaaa ttttaggagg aggatttgga acagttttat
    11461 acataggcga atatgcgtat ttcgtaagcg atttaccgta tcttcttttt ttacataatg
    11521 gatatttcac tactttactt gtttttggtg ttagtggggt catactattc gttttatggg
    11581 tacttagttt atttagttat agcaagtatg ttaatgatac ccaagattca aattttataa
    11641 aaggtcttgc tgtggttata ttatttacca catattttgt aaatggtcct cttttttctg
    11701 tttcacaagc caccttcttg ctttattttg cactttttag taataatcat ggagaattag
    11761 atgaagattt ttaaaaaaat taaatttata ttaatgctgc tttatacctc aacttttcca
    11821 agatgtgaga aaatactgat ttttggatca tggttaggtg aaaaatatgc agacaatcca
    11881 agatatttgt ttgagtatgt gattaagaat cgtcccgatt taaaagctat atggattaca
    11941 agtaatcaag atgtttttaa agaattacag aagaaacaat atcccgtgat gatggcagat
    12001 gagagtgaag ctcataaaat tatgaagaaa gctaaatata tttttacaac tacaggtatt
    12061 tttgatatcg gagtagaaaa tagtaggttg attggcggtg cttttttaat taacctttgg
    12121 catggcattc ctttgaaaaa aatcatgtat gatgataaac attcagcgct tcacaaacgt
    12181 agtaaactag tgacttgggt agaaaaaatt cctcttcgaa actattttgt tatttctact
    12241 agtacggcaa taactcaaat ttatcagtct gcttttcgcg taaagaaatc taatatatta
    12301 gaacttggac agcctagaaa tgactatttt tatgatgagt cttatccagt aagttcgcta
    12361 atacaagaat taaaaagtaa aaatattatc ttatatatgc cgacacatcg caatgaagga
    12421 aagaaacaaa ttcctctaga taatttaatg gatttaaatc gattaaataa atggtgtgaa
    12481 gaaacaaatt caatttttgt aattaaaaaa cacttctatc attcaaaaga aaaaacactt
    12541 gagaaagaat attcatcaat aattgatgtg acaaatgaga aggtcgatgc tcaagaatta
    12601 ctcaaatatt caaagatctt aataactgac tactcgagct gctatattga ctacttattg
    12661 ttggatcgac caattatatt ttttaattat gactatgatg attatttgag gattgatcgt
    12721 tcgctatatt ttccatatga gaaggttact ccaggggaga aatgtcaaaa ctttgatgaa
    12781 ttattagtga ctctgcaaaa tctatatcta ggaaaagatg attataggaa aaagcgtgaa
    12841 aatattaaaa ctttctttta ttctagtgaa actcagaagt cagtttctga aaaaatcatt
    12901 aatcacgtac taaatctata actttattgg aatctgtaat gaaaaaaata ttaaataagt
    12961 attattcttt atctaatcct gtaaaagctt caatttggtt tactatttgc aatgttcttc
    13021 aaaaaggaat ttcaatgatt actgttccaa tttttactag attattgaca acggaacaat
    13081 atggtgtata ctctgtatat caatcatggt attcaataat tggagttttt gcaacactaa
    13141 acctatatta tggagtcttt aataatggaa tggttaaata cgagaaagat aaaaatgcct
    13201 ttacttcctc tatgcaggga ctaacaacaa cagttacagc tatattttta gtgatatatt
    13261 taatagggat tgatttttgg aactcgttgt taggcttacc tacgctacta atcttagtga
    13321 tgttctttga tttgtttttt actcctgctt attctttttg ggctacgcgt cagagatttg
    13381 aatatcaata tcgaaactta gtatttatca cacttattat agcgattgga agccctatta
    13441 ttggtatttc ttcagttgtt ttatcgactt ataaagcgga ggctagagtt atctcatttg
    13501 tgttagttca atcttgtata ggattatatt tctatgtttt gaacctttac cgaggtaaat
    13561 attttttttg taaaaaatat tggctctatg ctttgaattt taatttacct cttattcctc
    13621 attatttatc gcaatcagtt ttaaatcaat cggatagaat aatgattaat tcaatggtag
    13681 gaatgggaga agcagctatt tatagtgttg cttacagcat atcaactttg atggttttag
    13741 tgacaagtgc tataaacagc tcttttattc cttacacata taagtgtatt cgagataaga
    13801 aatatactga actagggaaa agtgcaaatc ttttaattac tctggtaggc attggttcga
    13861 ttttaactat ttctcttgga ccagaaatca ttcaattatt tgcaccaaaa caatattacg
    13921 aagcaatatg gattattcct ccagttgctc tttcagtata tttcatgttc ttatatccca
    13981 tttttggtaa cattgagttt tactttgaag caaatcattt tgtaatgtgg gcttcaatag
    14041 gtggagcaat tatgaatatt tttttgaatt ttatttttat aaaacacttt ggctatattg
    14101 cggcaggcta tacaacttta ttatgttata ttttatttgc attgggacat tacattttta
    14161 tgagaagagc attgtatcag aatctttcgg gtatccaaat ttatgattct cgatatattt
    14221 tctttttttc gtttcttctt ctgattctaa tgctactaat cgtgactatt tatccatttg
    14281 tgttgattcg ttatattgct atctcactca tcctaggagg atgtttttta aagaggagaa
    14341 agataatgag ttcgatagtc atgataaaaa aacagtgagg tacacgaatg acagaaataa
    14401 ataaacagtt acatgaaaca ttaatcgaaa ttttagactt tgtaaaagaa atttgtgaaa
    14461 aacatgaatt aacttatttt ttgatctatg gtacggcact cggtgcaaaa cgccattgtg
    14521 gatttattcc ttgggatgat gatgttgata ttgctttacc gcgagagcac tacaatatat
    14581 taatcgacgt gttatctaag atggaacaat ctatatttag tcttcaaaat gaagataacg
    14641 agccgaacta ttttttacca tttgctaaat taagaaaaaa caatacgatt tttattgaaa
    14701 agattcttga tgttgaatat gagaataacg gtatttacat tgatattttt ccactagatt
    14761 tcgtagagaa tccggactct tttaatttta agatgaggag aactatgttt aattatataa
    14821 agcatatttt aaaattttca agttgcagaa gtttttataa aaataaatac agtagcgtac
    14881 gttatttgat ggaaaatatt atgagtattc ctaccctgtt tttttcaaat aggagattac
    14941 tattcttagc gaataattta atttcatcaa cgaataaagc taattttatt ggtcaatatg
    15001 atgaaagtag cgaaagagct atcatgcctt caagctatta tttcccgtct agatccgctg
    15061 tgtttgaagg aaagatttat agtgttcctg cgaaattaga agattattta aaatattttt
    15121 atggttcgga ttatatggaa ttaccaccaa tagaaaaaag agtcactcat caaccaataa
    15181 aacttagatt caaaaaataa ttggctattc tgtagaagga gaataattca agagttgtga
    15241 agtaaaacat tgggttattt ttaaggtaac gagatttgaa aaataatgat ttaaagatag
    15301 gaagtggagc tattcatcaa atttccgcta cactttctca aaatagtatt tcgggaaaga
    15361 ttttatattg tgctgatcca gttgtcgatg acttgtacgg ttcgatagta cgttcacaaa
    15421 tagaggaaat tggtcgggta aaggaagaaa gttgcaatta taatactatt gcttatgcga
    15481 tgaatatagc agaacgggct attgccacag atattgactg tattgtggga atgggaggag
    15541 gtcgtgtttt agatgtctgc aagtatgcat cttttatttc gaaacgtcct tacctatcga
    15601 ttccgacaac agcagcaaat gatggcattg cttccccagt tgctgttttg aaaaggcagg
    15661 atgatagacc aaaaagctta ggggcggcta tcccctcaat gacactaatt gatattgatg
    15721 ttattgcatc aggacctata caaaatataa aagctggtat cggtgataca atatccaatt
    15781 acactgcatt gaaagattgg gagttggcag ttgagcgagg gaaagatgag atgcatggtt
    15841 ttgcatatct aatgtcgcaa aattctttag atgctttaat gaaaacgaag tataattcta
    15901 ttacccctga ttttattgaa gttttggtaa actctttagt tttatcaggc attgcaatgg
    15961 attttgcggg aagtagtaga cctgtcagtg ggtcagagca cttatttagt catgcattag
    16021 attactatgg ttctacaagg aatcttcatg gaattcaggt tgcattaggt acagtcgcag
    16081 ttttgaaatt aattgaaaat tctgttgata ctgtagtgga ttacttgcaa agatttgagg
    16141 ttcatattaa cccgaaactt ttggggatag atgaagagtt gtttatttat tgtatgcaac
    16201 atgctacaaa aatgagaagt aatcgctata cttatctgca tgaagttgat cttagcacag
    16261 atagattgaa acaaatatat aaggaactca taagcgagtt gtagaaaaga gaggaaaaaa
    16321 tgaaagcact tattttagca gcagggttag gaacacgtct agctccaatt accaatgagg
    16381 taccaaaatc tttggtacca gtcaatggta agccaatttt gatgaaacaa attgaaaatt
    16441 tatatcaaaa taatattaca gatattacga ttattgctgg atataagtca tctgtattaa
    16501 cagatgcagt tactgaaaag tatccagaaa ttaatattat tgataatgtt gattttaaaa
    16561 cgactaataa tatgtattca gcctatctag gaaaagctgc aatgggtgat agtgacttct
    16621 taatgatgaa tgcagatgta ttttatgatg cttctgttat taaaagtctg ttgcttcata
    16681 aagctccaaa tgcaattgta actgatttag gtatttatat tgaagagtct atgaaagtcg
    16741 tagaaaaaaa tgggcgttta gtagaaattt ctaaacagat ttcacctgag gaaactttag
    16801 gagcttctat tgatgtttat aaattctctt atgaagcagg tgctcgattc tttgaaaagt
    16861 gtaaggaatt tattgaagat aaacgagaac ttcaaatgtg gagtgaggtt gctcttaatg
    16921 caattctttc tgaagttgaa tttgtagcat gtccattaga gggtcgttgg ttagaaattg
    16981 ataatcatga agacttagtt gctgcagaaa aactatttgc ttgaaccgaa tacggagaat
    17041 gaaattgaca aatagagttg attattttgg tgctgatatt agtgaacttc agaataaaaa
    17101 attattctta tttgatatgg atggtaccat ttatgaagaa gataggttgt ttgagggtac
    17161 tctcgaatta ttagactata ttcataatat tggcggtgag tatattttta ttacaaacaa
    17221 ttcatctaag tctgttgttg actatgttga aaaagttaac agattaggta ttaaagctga
    17281 acgagataat ttttttacct ctgctcaggc cacaattgtt tatattaaag aaaattatcc
    17341 taaatctaaa gtttattgcc aaggaacaaa atctttgata aaagaactat ctgacgcagg
    17401 aattgatgta actgagcaag ttagtgctga tatagatgtt gttcttgttg gttttgatac
    17461 agaattaacc agtgataaaa ttcgcaatac ctgcgagatt ctatcaacaa aggacgtacc
    17521 tttcatagct actaaccctg atattcgctg cccagtatcg tttggattca tcccggattg
    17581 tggttctatt tgtgatatga ttagtaaatc agtcgatagg aaacctgttt acataggtaa
    17641 acctgaacct acgatggttg atattgttcg aaaaaaatta aattattctc tatttgaaac
    17701 agttgtgatt ggagatcgct tgtatacgga tatcatgact ggtataaatg caggagtaac
    17761 ttcagtttgt gtgctgacag gagaagcaac ggtgaatgat attcaacaag atagtataaa
    17821 accgacttat acatttaaaa acgtgaaaga aatgtggaaa ggaattgtct gattttttca
    17881 ttctgaatag tgaattcatg aatactgtca aaatactcgt atgtatttaa attgatttca
    17941 ttattttaat aatggacaaa ttaaaattat ttttctcccc aaatcgttcg tgaacgtaaa
    18001 gtactcatca acaaagaaag gtaccccttt tatgaaaggt attattctag caggtggttc
    18061 gggaactcgc ttgtatcctt tgactcgagc cgcatcaaaa caacttatgc cggtttatga
    18121 taaaccgatg atttactacc cactttcaac attgatgttg gctgggatta gggatatttt
    18181 gattatttcc actccacagg atttacatcg atttcaagag cttcttcaag acggatctga
    18241 gtttgggatc aaactttctt atgcagagca accaagtcca gatggtttgg cacaagcctt
    18301 tatcattggg gaagagttta tttctgatga tagcgttgcg ctaatcttag gtgataatat
    18361 ctaccatggt tctgggcttt ccaagatgct acaaaaggca gcgagtaagg agtcgggagc
    18421 aactgttttt ggctaccatg tcaaggatcc agagcgcttt ggtgtggttg agtttgatca
    18481 ggatatgaag gctatttcta ttgaagaaaa gccagagcaa cctcgttcaa actatgcagt
    18541 tacaggtctc tatttctatg ataatgatgt agtagagatt gccaaaagta ttaaaccaag
    18601 tcctcgtggt gaattggaaa ttacagacgt taacaaggct tatctagaac gtggtgattt
    18661 gtctgttgag cttatgggac gtggctttgc ttggttggat actggcactc atgaaagttt
    18721 actagaggct tcgcagtaca tcgaaacagt ccaacggatg caaaatgttc aggtagcaaa
    18781 cttagaagaa attgcctatc gcatgggtta tatcagtcgt gaagatgtat tgaccttagc
    18841 ccaaccactt aagaaaaatg aatacggaca gtatctgctc cgtttgattg gagaagcata
    18901 gatgacagat aattttttcg gtaagacgct tgcggcacgc aaggttgaaa ctattccagg
    18961 catgttggag tttgatatcc ccgttcatgg agataatcgt ggctggttta aagaaaattt
    19021 ccaaaaggaa aaaatgcttc cacttggatt tccagagtct ttctttgcag aaggaaaatt
    19081 gcaaaacaat gtatccttct cacgtaaaaa tgtccttcga ggcctccacg cagagccttg
    19141 ggataagtac atctctgtag cagatggagg gaaagttctg ggttcttggg ttgatctacg
    19201 cgagggtgaa acctttggga atacctatca gacagtaatt gatgcaagca agggaatctt
    19261 tgttcctcga ggcgtagcta atggcttcca agttctatca gatacagtgt catatagcta
    19321 tctggtcaat gattactggg ctctcgagct caaacccaag tatgcctttg tgaactacgc
    19381 tgatccaagc cttggtattg aatgggaaaa tattgcagaa gcagaggttt cagaagcaga
    19441 taaatatcat cccctactta aggatgtaaa acctttgaaa aaagaagatt tgtaaaaagg
    19501 aaagaatatg actgaataca aaaatattat cgtgacaggt ggagctggct ttatcggttc
    19561 taactttgtc cattatgttt acgagaactt tccaggtgtt cacgtgacag tcctagataa
    19621 gttgacttat gctggaaatc gcgcgaatat tgaggaaatt ttaggtaatc gtgttgagtt
    19681 agttgttggt gacattgctg atgcggagtt ggtagacaag ttggctgctc aagcagatgc
    19741 tatcgttcat tatgcagcgg aaagccacaa tgataattcg ctcaatgatc catcgccatt
    19801 tattcatact aacttcatcg gaacctatac tcttttagaa gctgctcgta agtatgatat
    19861 tcgcttccac catgtatcga cagatgaagt ttatggggat ctccctttac gcgaagattt
    19921 gccaggtcat ggagaagggc cgggtgagaa atttacggct gaaaccaagt acaatccaag
    19981 ctcgccttac tcatcaacca aggcagcctc agatttgatt gtcaaagcct gggtccgttc
    20041 ttttggagtc aaggcaacga tttccaactg ttcaaataac tacggtcctt atcaacatat
    20101 cgaaaaattc atcccacgtc agattactaa catcctaagt ggaattaagc caaaacttta
    20161 cggtgaaggt aagaacgttc gtgactggat tcataccaat gaccattctt caggagtttg
    20221 gacaatcttg acaaaagggc aaattggtga aacctacttg attggggctg atggtgagaa
    20281 gaacaataag gaagttttgg aacttatcct taaggaaatg ggacaagctg cggatgccta
    20341 tgatcatgtg actgaccgtg caggacatga ccttcgctat gcgattgatg ctagcaagct
    20401 ccgtgatgag ttggggtgga aacctgaatt taccaacttt gaagctgggc tcaaggcaac
    20461 aatcaagtgg tatacagata accaagaatg gtggaaagca gaaaaagaag ctgttgaagc
    20521 caattatgct aagactcagg agattattac agtataaaaa gcaggaaata gctgcttttt
    20581 attgctatat tgggaagagt tacatattag aaaggtctag agatgatttt aattacaggg
    20641 gcaaatggcc aattaggaac ggaacttcgc tatttattgg atgaacgtaa tgaagaatac
    20701 gtggcagtag atgtggctga gatggacatt atcgatgcag aaatggttga gaaagttttt
    20761 gaagaggtga aaccgacttt agtctaccac tgtgcagcct acaccgctgt tgatgcagca
    20821 gaggatgaag gaaaagagtt ggacttcgcc atcaatgtga cggggacaaa aaatgtcgca
    20881 aaagcatctg aaaaacatgg tgcaactcta gtttatattt ctacggacta tgtctttgac
    20941 ggtaagaaac cagttgggca agagtgggaa gttgatgacc gaccagatcc acagacagaa
    21001 tatggccgta ctaagcgtat gggggaagag ttagttgaga agcatgtgtc taatttctat
    21061 attatccgta ctgcctgggt atttggaaat tatggcaaaa acttcgtttt taccatgcaa
    21121 aatcttgcga aaactcataa gactttaaca gttgtaaatg accagtacgg tcgtccgact
    21181 tggactcgta ccttggctga gttcatgacc tacctagctg aaaatcgtaa ggaatttggt
    21241 tattatcatt tgtcaaatga tgcgacagaa gacacaacat ggtatgattt tgcagttgaa
    21301 attttgaaag atacagatgt cgaagtcaag ccagtagatt ccagtcaatt tccagccaaa
    21361 gctaaacgtc cgctaaactc aacgatgagc ctggccaaag ccaaagctac tggatttgtt
    21421 attccaactt ggcaagatgc attgcaagaa ttttacaaac aagaagtgag ataagtagta
    21481 gaatgatttt ctagtctaat aaaagaggta gataatgaac tccaaaggag cttaagatat
    21541 acgattatct tgttgttggt gctggtctct ttggtgcata gctatggctc agtttctatt
    21601 atcgctcaca ccatccatca gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa
    21661 gattgggcta agatgggttt accaatcaca cgcaaggaaa tctctaattg gcatatcaag
    21721 acgagtcaat actatttgga gcccctctat aacctcttgc gagagagact attgactcag
    21781 cccttacttc atgcggatga aacttcttat agggtgctag agagtgatag tcagctgact
    21841 tactattgga cttttttgtc aggtaaatca gagaaacaag ggattacgct ttaccaccat
    21901 gatcagtgtc gaagtggttc agtagtacaa gaattcctag gagattattc tggctatgtg
    21961 cattgtgata tgttgtggca gtaacttagg actttagtcc tctagttctg cctatgcgat
    22021 agcagtccaa agtttaggag taaggcgacg ctaagcttgg taaactgcga acagctagaa
    22081 gcttatcgtc aactggaaga agctgcactt gttggatgtt gggcgcatgt gagaaggaag
    22141 ttttttgaag cgacccccaa gcaagcagat aaatcatcct taggagctaa aggtttagtt
    22201 tattgtgatc agttattttc cttggaaaga gactgggagg ctttgccagc tgatgaacga
    22261 ctacagaaac gtcaagaaca tctccaaccc ctactggaag acttctttgc ttggtgccgg
    22321 cgtcagtcag ttttatcggg ttcaaaacta ggaagggcaa ttgaatacag cctcaagtat
    22381 aaagaaacct ttaagaccat tttgaaagac ggacatctgg tcctttccaa taatctagct
    22441 gaatgcacca ttaaatcatt ggttatggga cggagtaaaa gagtccagtg gactctttta
    22501 gcctaagctc agtttaaaaa agcgagggtg gttattttct caaagttttg aaggagctaa
    22561 agcaagagct attattatga gtttgttgga aacagctaaa cgtcatcaat taaatagcga
    22621 gaaatatcta ttctatcttc tagaatgtct tccaaacgag gaaactctcg taaacaaaga
    22681 ggttttagag gtttatttat catggactaa agttgtacaa gaaaagtgca aataagaaat
    22741 ctccagatta ggaactatcc gtgagttctc tagtctggag atttttcaat atacttcgtt
    22801 attgggcggt tacgatattc atattttttg caaagatgtt gtttgaaaaa taattttcaa
    22861 aaattctgaa aattctgttg acaactttct gaaaagagtc tataatggag agaaagtttt
    22921 aaaggagaaa atgatgaaaa gttcaagact acttgccctt gcgggcgtga cattattg
//
