LOCUS       CR931695               22164 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain nr. 34374 (serotype 31).
ACCESSION   CR931695
VERSION     CR931695.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22164)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22164)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="nr. 34374"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC31_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC31_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34088.1"
                     /db_xref="GOA:Q4JZX1"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4JZX1"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTLAQEVFEKQILIP
                     WDAFCVELL"
     gene            322..474
                     /gene="aliB"
                     /locus_tag="SPC31_0002"
                     /pseudo
     CDS             322..474
                     /gene="aliB"
                     /locus_tag="SPC31_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
                     /db_xref="PSEUDO:CAI34089.1"
     gene            complement(order(491..1025,1027..1353))
                     /gene="tnp"
                     /locus_tag="SPC31_0003"
                     /pseudo
     CDS             complement(join(491..550,549..1025,1027..1353))
                     /gene="tnp"
                     /locus_tag="SPC31_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(963..1025,1027..1335))
                     /gene="tnp"
                     /locus_tag="SPC31_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 2.1e-22"
                     /pseudo
     gene            1588..3033
                     /gene="wzg"
                     /locus_tag="SPC31_0004"
     CDS             1588..3033
                     /gene="wzg"
                     /locus_tag="SPC31_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34091.1"
                     /db_xref="GOA:Q4JZX0"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JZX0"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKSQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAILQKLTST
                     EVLKNYSTIINSLQDSIQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1588..1704
                     /gene="wzg"
                     /locus_tag="SPC31_0004"
                     /note="Signal peptide predicted for SPC1454 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1792..2139
                     /gene="wzg"
                     /locus_tag="SPC31_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 1.3e-62"
     misc_feature    2317..2760
                     /gene="wzg"
                     /locus_tag="SPC31_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 4.4e-70"
     gene            3035..3766
                     /gene="wzh"
                     /locus_tag="SPC31_0005"
     CDS             3035..3766
                     /gene="wzh"
                     /locus_tag="SPC31_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34092.1"
                     /db_xref="GOA:Q4JZW9"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW9"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDFVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    3038..3646
                     /gene="wzh"
                     /locus_tag="SPC31_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1e-37"
     gene            3772..4467
                     /gene="wzd"
                     /locus_tag="SPC31_0006"
     CDS             3772..4467
                     /gene="wzd"
                     /locus_tag="SPC31_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34093.1"
                     /db_xref="GOA:Q4JZW8"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW8"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNRDQGDKSGLTNQDLQAGTYLVKDYREITLSQDVLEKVATNLKL
                     DMPAKTLASKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDV
                     TTLEEARPVTTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELIDTRVKRPEDVEDVLQI
                     PLLGVVPDLDKMK"
     misc_feature    3772..3888
                     /gene="wzd"
                     /locus_tag="SPC31_0006"
                     /note="Signal peptide predicted for SPC1456 by SignalP 2.0
                     HMM (Signal peptide probability 0.721) with cleavage site
                     probability 0.467 between residues 39 and 40"
     misc_feature    3793..4209
                     /gene="wzd"
                     /locus_tag="SPC31_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 2.8e-54"
     misc_feature    4315..4392
                     /gene="wzd"
                     /locus_tag="SPC31_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4477..5151
                     /gene="wze"
                     /locus_tag="SPC31_0007"
     CDS             4477..5151
                     /gene="wze"
                     /locus_tag="SPC31_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34094.1"
                     /db_xref="GOA:Q4JZW7"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW7"
                     /translation="MPTLEISQAKLDFVKKAEENYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGKK"
     gene            5250..5843
                     /gene="wcjG"
                     /locus_tag="SPC31_0008"
     CDS             5250..5843
                     /gene="wcjG"
                     /locus_tag="SPC31_0008"
                     /note="member of homology group 50"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34095.1"
                     /db_xref="GOA:Q4JZW6"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW6"
                     /translation="MDVFIGLFGTIFIVLPSSLMIYIIYKIKGYKGNIFFTQYRVGLK
                     GKKFKIIKFRSMVENAEEVLAANKALYEKYINNSYKLPPNEDPRLTNIGDFIRKTSID
                     EIPQFINLMLGDMSLIGPRPILENELEEYSKEEQQVLLSVRPGITGMWQVSGRSEVYY
                     PERCEMELYYPRNQSFLLDVKIFFLTIKKVLSGEGAH"
     misc_feature    5259..5840
                     /gene="wcjG"
                     /locus_tag="SPC31_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 2.4e-53"
     gene            6060..6854
                     /gene="wciB"
                     /locus_tag="SPC31_0009"
     CDS             6060..6854
                     /gene="wciB"
                     /locus_tag="SPC31_0009"
                     /note="member of homology group 16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34096.1"
                     /db_xref="GOA:Q4JZW5"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW5"
                     /translation="MSKKYKIIVATHKRFQMPEDKDLYVPVQVGSEGKENLGYQRDNQ
                     GNHISYLNPYYCELTGLYWAWKNLDCDYLGLVHYRRYFTDKNRPYHDKINMNEVILSA
                     DQVKELMSEVDVVVPKKRKYYIETLYSHYAHTHDSSHLDVTREIIKEVSPEYLATFDK
                     VMAYRSGYMFNMFIMSKENVSSYCEWLFPIIDELYRRLDITGYSAFDARLFGRVSERL
                     FNVWLDYQNLHVKELPFMYMEKVDLLEKGKSFLMAKFFGKKYGQSF"
     gene            6838..7935
                     /gene="wcrP"
                     /locus_tag="SPC31_0010"
     CDS             6838..7935
                     /gene="wcrP"
                     /locus_tag="SPC31_0010"
                     /note="member of homology group 89"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34097.1"
                     /db_xref="GOA:Q4JZW4"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW4"
                     /translation="MVRVFEMLEKKSPLFSVIVPTYKISESNLRQCIDSLLYDNQDVE
                     IILVDDNANSDICGEVIDEYAEKYNNISVIHQENQGVSVARNAAMSIAVGKYLVFVDP
                     DDWVAENFYSQMTFAVQKNPSSDVIILAAIVDYNGKRFTNHFWHTSRSFRGKVKDDLE
                     LQLIAKGATSYFPAEIGVGVPWAKIYRNEFVRANGLVFNPSLRRMQDNIFNMYAFEFA
                     NEIVYIDEPIYYYRKSMDSVTNKKNDKVIYYFDLVNDEVEKFILKFNKPKIFEDALHI
                     KRLIGINSYYKLYFQFASTSSEKKKMRQEFRELLEREEYANSLKQVNTAYLLPKEKIF
                     ISILKQKDLWIFSLLQKLEKLSVRLKSRQFS"
     misc_feature    6883..7422
                     /gene="wcrP"
                     /locus_tag="SPC31_0010"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1.2e-30"
     gene            8038..8931
                     /gene="wcrR"
                     /locus_tag="SPC31_0011"
     CDS             8038..8931
                     /gene="wcrR"
                     /locus_tag="SPC31_0011"
                     /note="member of homology group 90"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34098.1"
                     /db_xref="GOA:Q4JZW3"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW3"
                     /translation="MENVLNKKIGIVILNYLNWEDTLECINSLRSQSDQDFEAVIVEN
                     GSPNESVSRIRDYIKNDKNIHICVVDNNLGYANGNNMGILYLKNRYSINRILLTNNDV
                     VFDDEDYIKKLEDIKYSNTIGAIGTKIIGSDGLDQNPAYFPISFKSSIKLLIINLLAF
                     SKAFTFIKRRYLSSWAKKVNDFSAPRYNNQKYCLHGSVIFLTENYLDKFMGLYGGTFL
                     YYEEVILGIIFEKAGLDMLYIPNFSIYHKEDQSSLQSFNNDDLVRRRYLLQSIWSSMR
                     IYRSSIDNLSNIIENSIKEKL"
     misc_feature    8065..8565
                     /gene="wcrR"
                     /locus_tag="SPC31_0011"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 2.3e-13"
     gene            8928..10190
                     /gene="wzy"
                     /locus_tag="SPC31_0012"
     CDS             8928..10190
                     /gene="wzy"
                     /locus_tag="SPC31_0012"
                     /note="member of homology group 121"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34099.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW2"
                     /translation="MINSSKYLKFVLYYQIISFYFLGIFYRLSTFNQYLYVIADIVFI
                     SVYLLIFERKIAYTNIKLFIIFILFYLFGSFQGYDSGGAFIIFLLIYLKYILFKFIII
                     NIPQSNLIRAFTNIGILNTVILLAEVLSHGHINLFVNHYTLAQKIETLNKVGTNLAVL
                     RGGFENPLVTSVMLSSTLLFFMTIEKALLRNILIMSNLFLIMATEKRTGILISIALLF
                     CYYFRKNLKTKSVSKFIIKFLGGLFFLGFALLAINMITISGRSISQMIIERFSSLSSG
                     SDFSAIHRSMAFKIGIEIIWSRNILNILFGNGFYFLPTFMYNNNITITKLGFLVIDNS
                     YLSFLADFGMMPLISIMFYLIGGIFKNLVSNETDNISEVVMFSLIALLLSASVFDILN
                     WYQSTLLTCFFVAYLSVYHDSSKRKGNK"
     gene            10187..11431
                     /gene="wcrW"
                     /locus_tag="SPC31_0013"
     CDS             10187..11431
                     /gene="wcrW"
                     /locus_tag="SPC31_0013"
                     /note="member of homology group 122"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAI34100.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW1"
                     /translation="MTIKNEIKHLKRKIDKNFFQKDFTSISDIKNYQIAPSLNPRPRL
                     NLLITSMNSQDVYAGIKSAVDFFMKFKKFDIDLRIIVMGKKIDESSLYQVPGFEFIKD
                     YSIDNDSESRIICDLSKNRSPLFIRERDYFLSTMWYTAYNANNVLDEQKRIFGKRMPM
                     VYLVQDYEPGFYPWSSEYLLAESTYHLDNQLVVFNSKYLKEFFDANGYRFENSYYFDP
                     VLNEKLGEILNSAELSNIERKNRILFYGRPSKARNAFQLICMALEKWSLLDEHSSNWE
                     IFSAGEDLKDIKLNNNIVIKSLGKMSVEEYAKFMLESKIGISLMASPHPSYPPLEMAT
                     FGMKVITNSFVTKDISDFNENIISIEHININKLAKELHFLTTSDIEYKISKNDDYING
                     ISQLDTIVDKIGGHLQFQHSEV"
     gene            11434..12876
                     /gene="wzx"
                     /locus_tag="SPC31_0014"
     CDS             11434..12876
                     /gene="wzx"
                     /locus_tag="SPC31_0014"
                     /note="member of homology group 123"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34101.1"
                     /db_xref="GOA:Q4JZW0"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JZW0"
                     /translation="MKRKSIARNYLLNLIKTTLSILFPLISYPYVSRILSVDGLGAIN
                     FSASFVNYFVLIAIFGINVYAVREGAKYRDDKKLLGKFVTEMLLVSICTAMISFSLLT
                     VSLLLPALSEYRSLILIFSITIIFNVVGMEWFFQLMEDYQYITLRAIIFQILSLIFLF
                     IFVKDRNDIYVYALITVAANAGSQILNLFRLRKEVEIFRYKDYNIRNYFKPMFLIFLT
                     LLSMNIYRYLDVTFLGFFKNDRSVGYYSLATKITSAIISMVSSVTVILTPRLAYHYKK
                     EEFDKFYKIAYSSFDFILLLAIPVVIGVLSFSSILVDFLGGSTFVSSVLTVEILSLTI
                     LFSNLNALLITPILTVMNREKAVLKIFIIALIFNVITNMLLIPVMDFNGSALVTVLTE
                     GIICILSLISIKSVFNVRRLFKNLFQYLVASIFIIVVKIVISQYVSSNYIIFISTALL
                     SAILYFLTLILLRNELVPQLIIEVRKKIYR"
     misc_feature    11449..12255
                     /gene="wzx"
                     /locus_tag="SPC31_0014"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 7.1e-45"
     gene            12892..13572
                     /gene="wcrX"
                     /locus_tag="SPC31_0015"
     CDS             12892..13572
                     /gene="wcrX"
                     /locus_tag="SPC31_0015"
                     /note="member of homology group 124"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34102.1"
                     /db_xref="GOA:Q4JZV9"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="UniProtKB/TrEMBL:Q4JZV9"
                     /translation="MFTIYRAMKKIIIIILSLPKIFYINFKCLPLNQAVKLPIYVHFN
                     TRLMIRGDIKIIDTHLSRFTIILGKDGSNHISPHESRLFIYDGGQLILGRNILLSSGF
                     NLCIEQGGTVKLGDNVSFNRNSSIFCKKQINIGKNSLFGWNCSLRDNNGHRIYYQGNC
                     IKSEGVIVIGENCWITADSIILKNSVLPFSTVVATGSLVNKEFNQSNILIAGRPARII
                     RDDIKWER"
     gene            13640..14860
                     /gene="ugd"
                     /locus_tag="SPC31_0016"
     CDS             13640..14860
                     /gene="ugd"
                     /locus_tag="SPC31_0016"
                     /note="member of homology group 20"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAI34103.1"
                     /db_xref="GOA:Q4JZV8"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4JZV8"
                     /translation="MKIAVAGTGYVGLSIAVLMAQHHEVVAVDIISEKVNLINNGKSP
                     IKDDYIEEYLATKPLNLVATLDTNLAYQNADFVIIAAPTNYDSEKNFFDTSAVESVIE
                     TVLETNPNAVMVIKSTVPVGYTQSVRNKYKTSNILFSPEFLRESKALYDNLYPSRIIV
                     GLDMDDAYLKERAETFAELLQEGAIKEAIEILYMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDTKAIIEGIGLDPRIGNQYNNPSFGYGGYCLPKDSKQLLANYKDVPQ
                     NMITAIVESNRTRKDFIAEQILKFAGVSNNGEIYPKDVIIGLYRLTMKSNSDNFRQSS
                     IQGVMKRLKAEGANVIIYEPTLSDNETFFGSKIVNDLEHFKSISNVIVANRYDDLLKD
                     VSDKVYSRDIFKRD"
     misc_feature    13640..14194
                     /gene="ugd"
                     /locus_tag="SPC31_0016"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 9.2e-51"
     misc_feature    14225..14506
                     /gene="ugd"
                     /locus_tag="SPC31_0016"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 2.4e-36"
     misc_feature    14588..14839
                     /gene="ugd"
                     /locus_tag="SPC31_0016"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.1e-06"
     gene            14873..15973
                     /gene="glf"
                     /locus_tag="SPC31_0017"
     CDS             14873..15973
                     /gene="glf"
                     /locus_tag="SPC31_0017"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34104.1"
                     /db_xref="GOA:Q4JZV7"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JZV7"
                     /translation="MYDYLIIGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYINQFAEFNNYINSPVANYKGSLYNLPFNMNTFYT
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     misc_feature    15308..15910
                     /gene="glf"
                     /locus_tag="SPC31_0017"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 5.3e-139"
     gene            16001..16870
                     /gene="rmlA"
                     /locus_tag="SPC31_0018"
     CDS             16001..16870
                     /gene="rmlA"
                     /locus_tag="SPC31_0018"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI34105.1"
                     /db_xref="GOA:Q4JYY8"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4JYY8"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLT
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEHPRSNYAVTGIYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLGRGDLSVEVMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    16004..16720
                     /gene="rmlA"
                     /locus_tag="SPC31_0018"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 6.4e-118"
     gene            16871..17464
                     /gene="rmlC"
                     /locus_tag="SPC31_0019"
     CDS             16871..17464
                     /gene="rmlC"
                     /locus_tag="SPC31_0019"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI34106.1"
                     /db_xref="GOA:Q7BTQ6"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q7BTQ6"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     misc_feature    16907..17437
                     /gene="rmlC"
                     /locus_tag="SPC31_0019"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 8.8e-16"
     gene            17477..18526
                     /gene="rmlB"
                     /locus_tag="SPC31_0020"
     CDS             17477..18526
                     /gene="rmlB"
                     /locus_tag="SPC31_0020"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI34107.1"
                     /db_xref="GOA:Q4K121"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K121"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    17492..18448
                     /gene="rmlB"
                     /locus_tag="SPC31_0020"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 7.1e-05"
     misc_feature    17495..18235
                     /gene="rmlB"
                     /locus_tag="SPC31_0020"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 2.7e-76"
     misc_feature    17495..18331
                     /gene="rmlB"
                     /locus_tag="SPC31_0020"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0039"
     misc_feature    17498..18310
                     /gene="rmlB"
                     /locus_tag="SPC31_0020"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.6e-05"
     gene            18592..19443
                     /gene="rmlD"
                     /locus_tag="SPC31_0021"
     CDS             18592..19443
                     /gene="rmlD"
                     /locus_tag="SPC31_0021"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI34108.1"
                     /db_xref="GOA:Q4K1G6"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1G6"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    18592..19440
                     /gene="rmlD"
                     /locus_tag="SPC31_0021"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 4e-147"
     misc_feature    18595..19224
                     /gene="rmlD"
                     /locus_tag="SPC31_0021"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.9e-19"
     misc_feature    18595..19236
                     /gene="rmlD"
                     /locus_tag="SPC31_0021"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00013"
     misc_feature    18598..19326
                     /gene="rmlD"
                     /locus_tag="SPC31_0021"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2.9e-08"
     gene            19506..20615
                     /gene="glf"
                     /locus_tag="SPC31_0022"
     CDS             19506..20615
                     /gene="glf"
                     /locus_tag="SPC31_0022"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34109.1"
                     /db_xref="GOA:Q4JZV2"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JZV2"
                     /translation="MYDYIIVGAGLSGAIFAYEATKRGKKVKVIDKRNHIGGNIYCEN
                     VEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYVNSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKITEQTADMKDVEPKNLEEQAIKLIGPDVYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDEKNNAMFAKYQEEASKNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFGYDKK"
     misc_feature    19941..20543
                     /gene="glf"
                     /locus_tag="SPC31_0022"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 1e-138"
     gene            20563..21630
                     /gene="wcjE"
                     /locus_tag="SPC31_0023"
     CDS             20563..21630
                     /gene="wcjE"
                     /locus_tag="SPC31_0023"
                     /note="member of homology group 18"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI34110.1"
                     /db_xref="GOA:Q4JZV1"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4JZV1"
                     /translation="MNGRLRLWRKSLDMTKSRINWIDFGKGFSIFLVLAGHVLLGLYQ
                     SEKFPTANNILSLLIAQVYIFHIPVFFALSGYFFKPVSDLKEFWQYAKKKTIVFGLPY
                     IFYSIIHFGLQKVAGASVRVPTTISDLLNIYKDPLGVSWYLYILWSILIIYGLLSILV
                     KNRRMLFLISVFAYCLTLFVQTDIYIIQRTLVWGICFFLGSVLSEIHFDKINLKKFLF
                     FFVLFDFIYMFAWFLFYEVGSKKDYVSYSNPGLWGIAFIVCVLVAFAIFPKMEKNFPK
                     TFLYFTKYGKDSLGIYILHAPICSMIRILMLKVGINSVFIHVVVGIVLGWYLSILATY
                     ILKKIPFLNIVLLPQKYIKLK"
     gene            21805..>22164
                     /gene="aliA"
                     /locus_tag="SPC31_0024"
     CDS             21805..>22164
                     /gene="aliA"
                     /locus_tag="SPC31_0024"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34111.1"
                     /db_xref="GOA:Q4JZV0"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4JZV0"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVLSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    21805..21897
                     /gene="aliA"
                     /locus_tag="SPC31_0024"
                     /note="Signal peptide predicted for SPC1474 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.782 between residues 31 and 32"
     misc_feature    22051..22119
                     /gene="aliA"
                     /locus_tag="SPC31_0024"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     7198 a   3309 c   4448 g   7209 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
      121 aatcttaatt ccatgggatg ctttctgtgt ggaattacta taaatatttt ttacagaaaa
      181 atttaaaatt gaaatcgtat aaaaacaagg gaggactgta taaaagacag aaatcctttg
      241 ttttttataa ccaaggttta taaactttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gatgaacata aagaagcgtg tccttagtgc aggtctgact
      361 tttgcatctg ctttgctttt agctgcttgc ggccaatcag gttcagatac aaaaacttac
      421 tcatcaacct ttagtggaaa tccaactaca tttaattacc tgttagacta ttaatctgat
      481 gatatattca atcgaaacaa gaacaagaca aaagagcctt gtaaaaggta ttgcaatttg
      541 gtaatacctt ttatgaggtg ctttttgata tgagcccatg ttttctcaat aggattgtac
      601 tcaggtgagt agggaggaag aggtaaaagt ttatgcccaa actcttcaca caagagctct
      661 aacttcccca ttctatggaa tcttgcatta tccataataa taaccgatgg tgtgtttaat
      721 gttggtaaga aaaacttctg aaaccaagct tcaaaaaagt cgctcgtcat cgtctcttcg
      781 taagtcattg gagcgattaa ctcaccattt gttagacctg caaccaaaga aatcctctga
      841 tatcttcttc cagatacttt tcctcttctt aactgacctt ttaatgagcg accatattct
      901 cgataaaaat aagtatcgaa tcctgtttcg tcaatctaaa caggtgctag gtgctttaaa
      961 ctattaaaat tcttaagaaa taaggctact ttttctgggt cttgttcata gtaggtgtgg
     1021 ttcttttttt cgagtgtagc ccatagcttt gagcgcatag tggatggtag ttggatgaca
     1081 gccaaattca gaagctattt cagtcaaata agcgtctgga ttgtcagtaa gatagttttt
     1141 aagtctatct ctatcaactt ttcttggttt tattcctttt acttggtggt ttagctctcc
     1201 tgttttctct tttagcttta accagccata aatggtatta cgtgagattt ggaaaacgta
     1261 tgatgcttct gttatactac ctgttcgctc acaataagag agaacttttt tacgaaaatc
     1321 tattgaatat gccataagaa gattatacca cattgtgtac tatattatat tgaaactaga
     1381 atagtacacc tttgcttcta aaacattgtt agaaatcgat tggactgtcc tgaacgattt
     1441 gttctgttct tatttcattt tactatattt ttgtttcgcg ggaagtctac taagatactt
     1501 aaagatgcag atagtaaaaa taaaggtgta gacattaccg taaaaaagtg atataatcgt
     1561 acagtgttca atgtataggt attaatcatg agtagacgtt ttaaaaaatc acgttcacag
     1621 aaagtgaagc gaagtgttaa tatagttttg ctgactattt atttattgtt agtttgtttt
     1681 ttattgttct taatctttaa gtacaatatc cttgctttta gatatcttaa tctagtggta
     1741 actgcgttag tcctactagt tgccttggta gggctactct tgattatcta taaaaaagct
     1801 gaaaaattta ctatttttct gttgctgttc tctatccttg tcagctctgt gtcgctcttt
     1861 gcagtacagc agtttgttgg actgaccaat cgtttaaatg cgacttctaa ttactcagaa
     1921 tattcaatca gtgtcgctgt tttagcagat agtgagatcg aaaatgttac gcaactgacg
     1981 agtgtgacag caccgactgg gactgataat gaaaatattc agaaattact agctgatatc
     2041 aagtcaagtc agaataccga tttgacggtc aaccagagtt cgtcttactt ggcagcttac
     2101 aagagtttga ttgcagggga gactaaggcc attgtcctaa atagtgtctt tgaaaacatc
     2161 atcgagtcag agtatccaga ctacgcatcg aagataaaaa agatttatac taagggattc
     2221 actaaaaaag tagaagctcc taagacgtct aagagtcagt ctttcaatat ctatgttagt
     2281 ggaattgaca cctatggtcc tattagttcg gtgtcgcgat cagatgtcaa catcctgatg
     2341 actgtcaatc gagataccaa gaaaatcctc ttgaccacaa cgccacgtga tgcctatgta
     2401 ccaatcgcag atggtggaaa taatcaaaaa gataaattaa cccatgcggg catttatgga
     2461 gttgattcgt ccattcacac cttagaaaat ctctatggag tggatatcaa ttactatgtg
     2521 cgattgaact tcacttcttt cttgaaaatg attgacttat tgggaggggt agatgttcat
     2581 aatgatcaag agttttcagc tctacatggg aagttccatt tcccagtagg gaatgtccat
     2641 ctagactctg agcaagcttt aggttttgta cgtgaacgct actcactaac cgatggagac
     2701 cgtgaccgtg gtcgcaacca acaaaaggtg attgtggcta tccttcaaaa attaacgtca
     2761 accgaagtac tgaaaaatta tagtacgatc attaatagct tgcaagattc tatccaaaca
     2821 aatatgccga ttgagactat gatagattta gtgaatactc agttggaaag tggagggaat
     2881 tataaagtaa attctcaaga tttaaaaggg acaggtcgga tggatcttcc ttcttatgca
     2941 atgccagaca gtaacctcta tgtgatggaa atagatgata gtagtttagc tgtagttaaa
     3001 gcagctatac aggatgtgat ggagggtaga tgaaatgata gacatccatt cgcatatcgt
     3061 ttttgatgta gatgacggtc ccaagtcaag agaggaaagc aaggctctct tggcagaatc
     3121 ctacaggcag ggggtgcgaa ctattgtctc tacctctcac cgtcgcaagg gtatgtttga
     3181 aactccggaa gagaagatag cagaaaactt tcttcaggtt cgggaaattg caaaagaagt
     3241 agcagatgat ttagtcattg cttacggggc tgaaatttac tacacaccag atgttctgga
     3301 taagctggga aaaaagcgga ttccgaccct caatgatagt cgttatgcct tgatagagtt
     3361 tagtatgaac actccttatc gcgatattca tagcgccttg agcaagatct tgatgttggg
     3421 aattactcca gtcattgccc acattgagcg ctatgatgct cttgaaaata atgaaaaacg
     3481 cgttcgagaa ctgatcgata tgggctgtta cacgcaagta aatagttcac atgtcctcaa
     3541 acccaaactt tttggcgaac gttataaatt catgaaaaaa agagctcagt attttttaga
     3601 gcaggatttg gtccatgtca ttgcaagtga tatgcacaat ctagacggta gacctcctca
     3661 tatggcagaa gcatatgact ttgttaccca aaaatacgga gaagcgaagg ctcaggaact
     3721 ttttatagac aatcctcgaa aaattgtaat ggatcaacta atttaggaga aatgatgaaa
     3781 gaacaaaaca cgatagaaat cgatgtattt caattattta aaaccttgtg gaaacgcaag
     3841 ttaatgattt tattagtggc acttgtgaca ggtgcggggg cttttgcata tagcactttt
     3901 attgttaagc cagaatatac gagtaccacg cgaatttacg tagtgaatcg cgatcaagga
     3961 gacaagtcgg ggctgacaaa tcaggatttg caggcaggaa cttatctggt aaaagactac
     4021 cgtgagatta ccctttcgca ggatgtattg gaaaaagtag cgacaaattt gaagttggat
     4081 atgccagcaa aaacattagc cagcaaagtt caagtgactg taccagctga cactcgtatc
     4141 gtctcaatct ctgtcaagga taaacagcca gaggaagcca gtcgtatcgc taattctcta
     4201 cgagaagttg ctgcagaaaa gatcgtcgct gtaacgcgag tatctgatgt aacgacactt
     4261 gaagaagcgc gaccagttac gactccctct tctccaaatg ttcgacgcaa ttccttgttt
     4321 ggttttcttg gaggagcagt cgtaacagta attgctgttc ttttgattga gttgatcgac
     4381 acccgtgtga aacgtcctga agatgtcgaa gatgtactgc aaattccact tttaggggtc
     4441 gttccagatt tggacaaaat gaaataggag gaaattatgc caacgttaga aatttcacag
     4501 gcaaaattgg attttgtaaa aaaggcagag gaaaattata acgctttgtg cacgaaccta
     4561 cagttaagtg gagatgattt gaaagtattt tctatcactt ctgtgaaact aggagaagga
     4621 aaatcaacga cttccaccaa tatcgcttgg gcttttgcgc atgcaggtta caaaacgctg
     4681 ctgattgatg gagatattcg caattctgtt atgttaggtg tctttaaagc aagggataag
     4741 attacaggcc tgacagaatt tttatcagga actacagacc tatcacaagg gctttgtgat
     4801 accaatatcg aaaatctctt tgtaattcag gctggctctg tgtcaccgaa tccgacagct
     4861 cttcttcaaa gtaagaattt cagtacaatg cttgaaacct tgcgtaaata ttttgactac
     4921 atcattgtag atactgctcc tgtcggtgtc gtgattgatg cggctattat tacgcgaaaa
     4981 tgcgatgctt ctattttagt gacggaggca ggtgaaataa atcgacggga tattcaaaaa
     5041 gcaaaagaac agttggaaca cacagggaag ccgtttttgg gagttgtgtt gaataaattc
     5101 gatacttcag tagacaaata cggttcttat gggaactatg gaaagaaata aataatcttg
     5161 tagtaccaag gttatttgag atgattacca tgagaggaga gtttaaggtg aaacagaatg
     5221 gcatcatcta tattggcttt aaaagaatta tggatgtttt tatcggctta tttgggacaa
     5281 tattcatagt cttgcctagt tctttaatga tttatattat ttataaaata aaaggttaca
     5341 aaggaaatat attcttcaca caatatagag tggggctaaa ggggaaaaaa tttaaaatta
     5401 ttaaatttag atcaatggtt gaaaatgctg aagaagtttt ggccgcaaat aaagcactct
     5461 atgaaaaata tataaataac agttataaat tacctccaaa tgaggatcct cgtcttacca
     5521 atatcggaga ttttataaga aaaacgagta ttgatgaaat tcctcaattt ataaatttaa
     5581 tgttaggtga tatgagtctt attggaccta gaccgatttt ggagaatgag ttagaggagt
     5641 attctaagga agaacagcaa gttttgttat ctgtacgacc aggtattaca gggatgtggc
     5701 aagtttctgg taggagtgag gtatattatc ctgaacgctg tgaaatggag ctgtactatc
     5761 ctcggaacca atcctttttg ttggatgtaa aaatcttctt tttgacaata aaaaaagttc
     5821 tatctggaga aggggctcat tgatgtatga gctaaatcat ctagcaaaaa atagatagaa
     5881 agaagaagtt gaatacggat agcgtttctt gggtattcgt attcattttt tcaagtgaag
     5941 gaagcattat gaataagtgg atttaatcta gtgtttttgc ttgaaaaaat ggatgggaat
     6001 tcaatctaaa gaattgtcca gtgaggcaag attttaggaa ttggagttag gatgtagaaa
     6061 tgtcaaaaaa gtataaaatt atagtagcga ctcataaaag atttcaaatg ccagaagata
     6121 aggacttata tgttcctgtt caggttggca gtgaaggaaa ggaaaattta ggctaccaac
     6181 gagataatca aggtaatcat atttcatatc ttaatcctta ttattgtgag ttgacaggat
     6241 tatactgggc ttggaaaaat ttagactgtg attatctagg attagttcat taccgacgtt
     6301 attttacaga taagaaccga ccttatcatg ataagattaa catgaatgaa gttatcctat
     6361 cggctgatca agttaaggag ctcatgtctg aagtagatgt cgttgttccc aaaaagagaa
     6421 aatattatat agaaactctc tattctcatt atgctcacac tcatgattcc agtcatttag
     6481 atgtaacacg agaaattata aaagaggttt cgccagaata tttagcaaca tttgacaagg
     6541 tgatggccta tcgtagcggc tacatgttca atatgtttat catgtccaaa gaaaatgtat
     6601 catcttattg tgagtggttg ttccctatca ttgatgagtt gtacagaaga ttggacataa
     6661 cagggtactc tgcttttgat gcaagactat ttggacgtgt tagtgaacgt ctctttaatg
     6721 tttggttaga ttaccaaaat ctacatgtta aagaacttcc gtttatgtat atggaaaagg
     6781 tggatttgct tgaaaaaggg aaatccttct taatggcaaa atttttcgga aagaagtatg
     6841 gtcagagttt ttgaaatgtt agaaaaaaaa tctccacttt ttagtgttat tgttccaacc
     6901 tataagatat cagaatctaa tctacgccag tgcatagact ctctgttata tgataatcaa
     6961 gatgttgaaa ttattttggt agatgataat gcaaactcag atatatgtgg tgaagtgata
     7021 gacgaatatg ctgaaaaata taataatatt tcagttattc atcaggaaaa ccaaggtgtg
     7081 tcagtcgcaa gaaatgctgc tatgtctatt gctgtaggaa agtatcttgt ttttgtagac
     7141 cctgatgatt gggttgctga aaatttttat agccaaatga cttttgcggt tcaaaaaaat
     7201 ccttcaagtg atgtgattat attagctgct attgtagact ataatggtaa acgatttacg
     7261 aatcattttt ggcacacttc tcgttctttt cgtggaaaag tcaaagatga tttggaactt
     7321 caattgattg ccaaaggagc aacgagttat tttccagctg agataggggt tggtgttcct
     7381 tgggcaaaaa tttatcgtaa tgagtttgtg cgagcaaatg gcttggtttt taatccttct
     7441 cttcgtcgaa tgcaagataa cattttcaat atgtatgcat ttgaatttgc gaatgagatc
     7501 gtctacattg atgagccgat ttactattat agaaagagca tggatagtgt aactaataag
     7561 aaaaatgata aagtaattta ttatttcgac ttagttaatg atgaggttga aaaatttatt
     7621 ctaaaattta ataagcctaa aatatttgaa gatgctctac atataaaaag acttatagga
     7681 atcaattcgt attataagtt gtattttcag tttgcgtcta cttcaagcga gaaaaagaaa
     7741 atgcgacaag aatttcgtga acttttagaa agggaagaat atgcaaattc gttaaaacaa
     7801 gtgaatacag cctatcttct cccaaaagaa aaaattttta taagcatttt aaagcagaaa
     7861 gacttatgga tattctcatt gttacaaaaa cttgaaaaat tgtctgtgag gttgaagagt
     7921 cgacagttta gttagaggga atatgagaca gttacagtag ggatttataa gccgatatat
     7981 aaatccaaat atattagaga aaaaatgtta ggaaacggtt tataaaaatt gtagaggatg
     8041 gagaatgtct tgaataaaaa aataggaatt gttattttaa attatcttaa ttgggaggac
     8101 actttagaat gcataaatag tttgcgctca caaagtgatc aagattttga agctgtcata
     8161 gtagaaaatg gttctccaaa tgaatctgtt tctaggatta gagattatat aaaaaacgac
     8221 aagaatattc atatttgtgt agtggataat aacttaggtt atgcaaatgg aaataatatg
     8281 ggcatcctct acttaaaaaa tagatactct ataaatagaa ttctattaac taataatgat
     8341 gttgtttttg atgatgaaga ctacataaaa aaattagaag atattaagta tagtaatact
     8401 attggagcga ttggaacaaa aattattggt tctgatggct tagatcaaaa tccagcctat
     8461 tttccaatat cttttaaatc aagtattaaa ttgttgatta tcaatttatt agctttttct
     8521 aaagctttta cttttattaa aagacgttat ctatcttcat gggcgaaaaa agttaatgat
     8581 ttttcggctc caagatacaa caatcaaaaa tattgtttac atggatcagt tatctttctt
     8641 accgagaatt atttagataa atttatggga ttgtatggtg gaacttttct ttactatgaa
     8701 gaagtgattt taggtattat atttgaaaaa gcaggtctcg atatgttgta tatacctaac
     8761 ttctcaatct atcataaaga agatcaatcg tcgctacaaa gttttaataa tgatgactta
     8821 gtgcgacgtc gttatttgtt gcaaagtatt tggtctagta tgcgaatata tagaagctca
     8881 atagataacc tatctaatat tatagaaaat tcaatcaagg aaaaattatg attaattcgt
     8941 ctaagtatct taaatttgtc ttatattatc agataatatc attttatttt ttaggtattt
     9001 tttataggct atctactttt aatcaatatt tatatgtaat agcagatata gtttttatat
     9061 cagtatactt attgatattt gagcgtaaaa tcgcttatac taatataaaa ctatttatta
     9121 tctttatttt attctatcta tttggaagtt ttcaaggata tgatagtggt ggtgcattta
     9181 ttatattttt actaatttat ttaaaatata ttttattcaa atttataatt ataaatatac
     9241 cgcaatccaa tttaataaga gcatttacaa acataggtat tttaaatacg gtcattttat
     9301 tagcagaagt tttaagtcac ggacatatta atttatttgt gaatcattat actttggcgc
     9361 agaaaataga aaccttaaat aaggttggga caaaccttgc ggttttacgt ggggggtttg
     9421 aaaatccctt agtgacatct gtaatgctat cttctacatt attatttttt atgactattg
     9481 agaaggctct cttacgtaat atactaatta tgtctaactt atttttgatt atggcaacag
     9541 aaaaaagaac aggaattcta attagtatcg cgttgttgtt ctgttactat ttcagaaaaa
     9601 atttaaaaac aaagagtgtt agtaagttta taataaaatt cttgggagga ttgtttttct
     9661 tgggatttgc tttattagcc ataaatatga taacaatttc tggtcgtagc atttctcaga
     9721 tgataataga gaggttttca tcattaagta gtggttcaga cttttctgct atacataggt
     9781 caatggcttt taaaataggc atagaaataa tttggagtag gaatatattg aatatattat
     9841 tcggtaatgg tttctacttt ttgccaactt ttatgtacaa taataatatt acgattacaa
     9901 agttgggttt tttagtaata gataattctt atttatcttt tttagccgat tttggcatga
     9961 tgcctttaat aagtataatg ttttatctta tagggggtat ctttaagaat cttgtttcga
    10021 atgagactga taatatttca gaagtagtta tgtttagctt aattgcattg cttttatcgg
    10081 cgagtgtgtt cgatatttta aactggtatc agagtactct tttaacatgc ttttttgttg
    10141 cttatttaag tgtatatcat gattctagca aaaggaaagg gaataaatga ctatcaaaaa
    10201 tgaaattaaa catttaaaac gaaaaataga taaaaatttt tttcaaaaag atttcacttc
    10261 catctctgat attaagaact atcagattgc accttctttg aatcctagac cacgtcttaa
    10321 tttattaatt acttcaatga attctcagga tgtatatgct ggcatcaaat cagccgtgga
    10381 tttttttatg aagttcaaaa aatttgatat agatttaaga atcattgtaa tggggaaaaa
    10441 aatcgatgaa tcgtctcttt atcaagttcc tggttttgaa tttattaaag actattcaat
    10501 tgataatgat agtgagtcta ggattatttg cgatttatct aagaatcgtt ctccattatt
    10561 tattagggag cgtgattatt ttctatcaac aatgtggtac accgcttata atgctaacaa
    10621 tgtgttggat gagcaaaaaa gaatttttgg gaaacggatg cccatggttt atctagttca
    10681 agactatgaa ccaggtttct atccatggtc ctcagagtat cttttggctg agagcacata
    10741 tcatctagat aaccagcttg ttgtctttaa ttctaagtat ttaaaagaat tttttgatgc
    10801 aaatggttat agatttgaaa atagttatta ttttgatcca gttttaaatg aaaaattggg
    10861 ggagattctt aattcagcag agctttctaa tattgaaagg aaaaatcgta ttttatttta
    10921 tggaaggcct agtaaagcta gaaatgcttt tcagttaatc tgtatggcat tggaaaaatg
    10981 gagcctttta gacgaacata gttcaaattg ggaaattttt tctgcaggag aagatttaaa
    11041 agatattaaa ttgaataata acatagtaat aaaatcgtta gggaagatgt cagttgaaga
    11101 atacgcaaaa tttatgttgg aatctaaaat cggaatctct ctaatggctt caccgcatcc
    11161 gagctatcct ccgttagaaa tggctacatt tggtatgaaa gtcataacga attctttcgt
    11221 tacaaaagat atttctgatt ttaatgaaaa cataatttct attgaacata ttaatattaa
    11281 taaattagcg aaagaattac attttttaac aacatctgat atagaatata aaatttcgaa
    11341 aaacgatgat tatataaatg gtattagcca gcttgataca attgtagata aaattggagg
    11401 acatttacaa tttcagcata gcgaggtgtg attgtgaaaa ggaaatccat tgcccgaaat
    11461 tatttactta atttgataaa aacgaccttg tctattctat ttcccctgat atcataccca
    11521 tatgtgtcgc gtattttatc tgtggatggg ctgggtgcaa tcaatttttc agcctcgttt
    11581 gttaattatt tcgtactaat tgcaatcttt ggaattaatg tctacgctgt tagagaaggt
    11641 gccaaatatc gagatgataa aaagttactt gggaagtttg taacggagat gttacttgtt
    11701 agtatttgca cggcaatgat ttcattctct ttattaactg tttccttact cctacctgct
    11761 ctatcagaat atagaagtct tattctaatt ttttcaatta ccattatatt taatgttgtg
    11821 gggatggagt ggttttttca attgatggaa gactatcaat atataacact tcgtgcaatt
    11881 atatttcaaa ttctatcttt gatattttta ttcatatttg tcaaagatag gaatgatatt
    11941 tatgtgtacg ctctaattac agttgcagca aatgcaggtt ctcaaatact gaatttattt
    12001 agacttagaa aagaagttga aatatttaga tataaagact ataatattag aaattatttt
    12061 aaaccgatgt ttctgatatt tttaacctta ttgtctatga atatatatag atatttagat
    12121 gttacttttc tgggcttctt taaaaatgat cgaagtgtgg gctactatag cttagctaca
    12181 aaaataacaa gtgctataat ttcgatggta tcttctgtta cagttatttt gacacctcgt
    12241 ctagcatatc attataagaa ggaggagttt gataaattct ataaaattgc ttatagttcc
    12301 tttgatttta ttttattact tgctatacca gttgttatag gtgtattgag ttttagttct
    12361 attttagtag attttttggg tgggagtact tttgtttctt ctgtgttaac ggtggagata
    12421 ttaagtttaa caattctatt ctctaatttg aatgctttat taattacacc tattttaacg
    12481 gttatgaatc gtgagaaagc ggttttaaaa atttttatta tcgcattgat tttcaatgtt
    12541 attacaaaca tgttacttat tccagtaatg gattttaatg gttcagcttt ggttacagtt
    12601 ttgacagaag gaattatttg catattatct ttaattagta taaaaagtgt gtttaatgtt
    12661 agaaggctat ttaagaatct ttttcaatat ctggtagcta gtatctttat aattgttgtc
    12721 aagattgtta tttctcagta cgtttcatca aattatatta tttttatttc aactgcttta
    12781 ctaagcgcaa ttttatattt ccttactttg atattattga gaaatgagtt agtaccacaa
    12841 ttaataatag aagttagaaa gaaaatatat agatagtgga gttaaatata aatgtttacc
    12901 atatatagag ccatgaaaaa aataattata attattttgt cgcttcccaa gattttttat
    12961 ataaatttta aatgccttcc gttgaatcag gcggttaaac ttcctatata tgttcatttt
    13021 aatactcgat taatgattag gggagacata aaaatcattg atactcattt atcacgtttt
    13081 actattattt tggggaaaga tggctctaat catatctctc ctcatgagag tagattattt
    13141 atttatgatg gggggcaatt aattctaggg agaaatattc tattatctag tggatttaat
    13201 ttgtgtatag agcaaggagg tacggttaaa ttaggagata atgtctcttt taacagaaat
    13261 tcttcgatct tttgtaaaaa acaaattaat attggtaaaa atagtttgtt tggttggaac
    13321 tgtagtttac gtgataataa tggacatagg atctattatc aggggaactg tattaagagt
    13381 gaaggagtta ttgtaatagg agagaattgc tggataacag cagactcaat cattcttaaa
    13441 aatagtgttc ttcctttttc tactgtagtt gctacaggta gtttagtaaa taaagagttt
    13501 aatcagagta acattttgat agctggaagg cctgctagaa ttattagaga tgatataaaa
    13561 tgggaaagat aagatagtaa ttgattaatt aggtcgtgta atttttaaca gagataacga
    13621 aaggtaatgg gtgaagtaaa tgaaaattgc agttgcaggt acaggctatg taggactatc
    13681 tattgcagtt ttaatggctc agcatcatga ggtggtagct gttgatatta tttctgaaaa
    13741 ggtcaatctg attaataatg gaaaatctcc aattaaggat gactatattg aagaatactt
    13801 agcaacaaag cccctcaact tagtggcaac attggataca aatctagcgt accaaaatgc
    13861 agattttgtt attatagcag ctccaacaaa ttatgattca gaaaagaact tttttgatac
    13921 atctgctgta gaatcagtta ttgaaacggt gttagagact aatcctaacg ctgtaatggt
    13981 aattaaaagt actgttcctg taggctatac tcaatcggtt cgtaataaat ataaaacaag
    14041 taatatttta tttagtccag aatttttacg tgagtcaaag gctttatatg ataatttata
    14101 tcctagccgt ataattgttg ggcttgatat ggacgatgca tatttaaagg agagagccga
    14161 aacttttgca gaactgctac aagaaggagc tattaaagag gctatagaaa ttctttacat
    14221 gggatttaca gaggcagaag cagtcaaact ttttgcaaat acatatttag ccttacgtgt
    14281 ttcttatttc aatgagttgg atacttatgc agaagttaaa gggctagata ccaaagctat
    14341 tattgaaggt attggcttag atccacgtat cggaaaccaa tataataatc cttcttttgg
    14401 atatggggga tattgccttc caaaagatag taaacaacta ttggcaaact ataaagatgt
    14461 tccacagaat atgataacag ctatcgttga gagcaatcgt actagaaaag attttattgc
    14521 agagcagatt ttgaaatttg caggagtttc aaataatggg gaaatttacc caaaagatgt
    14581 aataataggc ctttatcggt taactatgaa gagcaactcc gataattttc gtcaatcttc
    14641 tattcaaggt gttatgaaac gattgaaggc agaaggagca aatgtcataa tttatgagcc
    14701 aactcttagt gataacgaga cgttttttgg tagtaagatt gtaaatgatt tggaacactt
    14761 taaatcaatt agtaatgtta tcgtggcaaa tcgttatgat gatttgctta aagatgtgag
    14821 tgacaaggtt tatagtcgtg atatttttaa gagagattag gtagaagtta taatgtatga
    14881 ttatttaatc attggagctg gtttgtctgg tgcaatcttt gcgcacgaag ctacaaaacg
    14941 tggaaaaaaa gtaaaagtga ttgataaacg tgatcacatc ggtgggaaca tctattgtga
    15001 gaatgtagaa ggtatcaatg ttcataaata tggtgcccat attttccata cttctaataa
    15061 aaaagtttgg gactatatca atcaattcgc tgagtttaac aactatatca actcacctgt
    15121 cgcaaactat aagggaagtc tttataacct tcctttcaat atgaatacct tctatactat
    15181 gtggggcaca aaaactccac aagaagtgaa ggataagatt gctgagcaga cagctggtat
    15241 gaaggatgtt gagccgaaaa atctggaaga acaagctatc aagttgattg gtccggatat
    15301 ctatgaaaag ttgatcaagg gttatacaga aaagcaatgg ggacgctcag cgacagaact
    15361 tcctccattt atcataaaac gccttccagt tcgtttaacc tttgataata actattttaa
    15421 tgaccgttac caagggattc ctattggtgg ttacaatgtc atcatcgaaa atatgctgaa
    15481 agatgtagaa gttgaacttg gagtagactt ttttgctcat cgtgaagagt tggaagcatc
    15541 tgctaacaaa gttgtcttca caggaatgat cgaccaatat tttgactaca agcacggaga
    15601 gttagaatac cgtagccttc gttttgagca tgagatttta gacgaggaaa attatcaagg
    15661 gaatgctgta gtgaactata cagagcgtga gatcccttat actcgtatta tcgaacacaa
    15721 acattttgaa tatggaatgc agccaaagac agttatcacg catgaatatc cagctgactg
    15781 gaagcgtggg gacgagccct actatcctat taacgatgag aaaaataatg ctatgtttgc
    15841 taaataccaa gaagaagcag cgcagaatga taaagttatc ttttgtgggc gtttagcaga
    15901 ctataaatat tacgatatgc atgtggtgat tgaacgggcg cttgaggttg tggagaaaga
    15961 atttagtaat tgaaaaacaa cgaagaaagg ttgcttatat atgaaaggta ttattcttgc
    16021 aggtggttcg gggacacgat tatatccttt gactcgggct gcatcaaaac aacttatgcc
    16081 ggtttatgat aaacccatga tttactatcc tttgtcaacc ctgatgttga ctggaataaa
    16141 ggacattttg attatctcaa caccacagga tttgccccgt tttaaggact tgctcttgga
    16201 tggttccgaa tttgggatca agctttccta tgcggaacaa cctagtcccg atggacttgc
    16261 tcaggctttt attatcggtg aagagtttat cggtgacgat agcgttgcct tgattttagg
    16321 tgacaatatt taccatggtc ctggtctgag cacaatgctt caaaaagcag ccaagaaaga
    16381 gaaaggtgcg actgtttttg gctaccaagt gaaggatcca gagcgttttg gtgtggttga
    16441 gtttgataca gacatgaatg ctatttctat cgaagaaaag ccagagcacc ctcgttcaaa
    16501 ctatgcagtt acaggaatct atttctatga taatgatgta gtagagattg ccaaaagtat
    16561 aaaaccaagc cctcgtggtg aactggaaat tacagatgta aacaaggctt acctaggtcg
    16621 tggagattta tccgttgagg ttatgggacg aggctttgct tggctggata ctggaactca
    16681 tgaaagttta ttagaggctt cgcagtacat cgaaacagtc caacggatgc aaaatgttca
    16741 ggtagcaaac ttagaagaaa ttgcctatcg catgggttat atcagtcgtg aagatgtatt
    16801 gaccttagcc caaccactta agaaaaatga atacggacag tatctgctcc gtttgattgg
    16861 agaagcatag atgacagata attttttcgg taagacgctt gcggcacgca aggttgaagc
    16921 tattccaggc atgttggagt ttgatatccc cgttcatgga gataatcgtg gctggtttaa
    16981 agaaaatttc caaaaggaaa aaatgcttcc acttggattt ccagagtctt tctttgcaga
    17041 aggaaaattg caaaacaatg tatccttctc acgtaaaaat gtccttcgag ggctccacgc
    17101 agagccttgg gataagtaca tctctgtagc agatggaggg aaagttctgg gttcttgggt
    17161 tgatctacgc gagggtgaaa cctttgggaa tacctatcag acagtaattg atgcaagcaa
    17221 gggaatcttt gttcctcgag gcgtagctaa tggcttccaa gttctatcag atacagtgtc
    17281 atatagctat ctggtcaatg attactgggc tctcgagctc aaacccaagt atgcctttgt
    17341 gaactacgct gatccaagcc ttggtattga atgggaaaat attgcagaag cagaggtttc
    17401 agaagcagat aaacatcatc ccctacttaa ggatgtaaaa cctttgaaaa aagaagattt
    17461 gtaaaaagga aagaatatga ctgaatacaa aaatattatc gtgacaggtg gagctggctt
    17521 tatcggttct aactttgtcc attatgttta cgagaacttt ccaggtgttc acgtgacagt
    17581 cctagataag ttgacttatg ctggaaatcg cgcgaatatt gaggaaattt taggtaatcg
    17641 tgttgagtta gttgttggtg acattgctga tgcggagttg gtagacaagt tggctgctca
    17701 agcagatgct atcgttcatt atgcagcgga aagccacaat gataattcgc tcaatgatcc
    17761 atcgccattt attcatacta acttcatcgg aacctatact cttttagaag ctgctcgtaa
    17821 gtatgatatt cgcttccacc atgtatcgac agatgaagtt tatggggatc tccctttacg
    17881 cgaagatttg ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg aaacaaaata
    17941 caacccaagc tctccgtact catcaaccaa ggcagcctca gatttgattg tcaaagcctg
    18001 ggtgcgttct tttggagtca aggcaacgat ttccaactgt tcaaataact acggtcctta
    18061 tcaacatatc gaaaaattca tcccacgtca gattactaac atcctaagtg gaattaagcc
    18121 aaaactttac ggtgaaggta agaatgttcg tgactggatt cataccaatg accattcttc
    18181 aggagtttgg acaatcttga caaaagggca aatcggtgaa acctacttga ttggggctga
    18241 tggtgagaag aacaataagg aagttttgga acttatcctt aaggaaatgg gacaagctac
    18301 ggatgcctat gatcatgtga ctgaccgtgc aggacatgac cttcgctatg cgattgatgc
    18361 cagcaagctc cgtgatgagt tggggtggaa acctgaattt accaactttg aagctgggct
    18421 caaggcaaca atcaagtggt atacagataa ccaagaatgg tggaaagcag aaaaagaagc
    18481 tgttgaagcc aattatgcta agactcagga gattattaca gtataaaaac caggaaatag
    18541 ctgcttttta ttgctatatt gggaagagtt acatattaga aaggtctaga gatgatttta
    18601 attacagggg caaatggcca attaggaacg gaacttcgct atttattgga tgaacgtaat
    18661 gaagaatacg tggcagtaga tgtggctgag atggacatta ccaatgaaga aatggttgag
    18721 aaagtttttg aagaggtgaa accgacttta gtctaccatt gtgcagccta caccgctgtt
    18781 gatgcagcag aggatgaagg aaaagagttg gacttcgcca tcaatgtgac ggggacaaaa
    18841 aatgtcgcaa aagcatctga aaagcatggt gcaactctag tttatatttc tacggactat
    18901 gtctttgacg gtaagaaacc agttggacaa gagtgggaag ttgatgaccg accagatcca
    18961 cagacagaat atggacgcac taagcgtatg ggggaagagt tagttgagaa gcatgtgtct
    19021 aatttctata ttatccgtac tgcctgggta tttggaaatt atggcaaaaa cttcgttttt
    19081 accatgcaaa atcttgcgaa aactcataag actttaacag ttgtaaatga ccagtacggt
    19141 cgtccgactt ggactcgtac cttggctgag ttcatgacct acctagctga aaatcgtaag
    19201 gaatttggtt attatcattt gtcaaatgat gcgacagaag acacaacatg gtatgatttt
    19261 gcagttgaaa ttttgaaaga tacagatgtc gaagtcaagc cagtagattc cagtcaattt
    19321 ccagccaaag ctaaacgtcc gctaaactca acgatgagcc tggccaaagc caaagctact
    19381 ggatttgtta ttccaacttg gcaagatgca ttgcaagaat tttacaaaca agaagtgaga
    19441 taagtagtag aatgattttc tagtctaata aaagaggcag agaatgaact ccaaaggagc
    19501 ttaagatgta cgattatatt attgtcggtg ctggtttgtc aggagcaatt tttgcttatg
    19561 aggcgaccaa gcgtggaaaa aaagtaaaag tgattgataa acgtaaccac attggtggga
    19621 atatctactg tgagaatgta gaaggagtta atgttcataa atatggtgcc catatctttc
    19681 atacttctaa taagaaagtt tgggattatg ttaatcaatt tgctgaattt aacaactacg
    19741 tcaactcgcc tgtagctaat tacaagggta gcctctataa tctacctttc aatatgaata
    19801 ccttctatgc tatgtggggg acaaaaactc ctcaagaagt caaagataag attactgagc
    19861 agacagctga tatgaaggat gttgagccga aaaatctgga agaacaggct atcaagttga
    19921 ttggtccaga tgtctatgaa aagttaatca agggttatac tgaaaagcag tggggacgct
    19981 cagcaacgga acttcctcca tttatcatta aacgtcttcc agttcgttta acatttgata
    20041 ataactattt taacgaccgt taccaaggaa ttcctattgg tggttacaat gtcatcatcg
    20101 aaaatatgct taaagacgtt gaagttgagc ttggtgttga tttctttgct catcgtgaag
    20161 agttagaagc atcagctgaa aaagttgtct ttacagggat gatcgaccag tattttgact
    20221 acaagcacgg agagttagaa taccgtagcc ttcgttttga gcatgagatt ttagacgagg
    20281 aaaattatca aggaaatgct gtagtgaact atacggagcg tgagattcct tatactcgta
    20341 ttatcgaaca caagcatttt gaatatggaa cgcaggcaaa gacagttatc acgcgtgaat
    20401 atccagctga ctggaagcgt ggggacgagc cttactatcc gatcaacgat gagaaaaata
    20461 atgctatgtt tgctaagtac caagaggaag cttcaaagaa tgataaggtt attttctgtg
    20521 gacgtttagc agattataaa tattatgata tgcatgtggt gattgaacgg gcgcttgagg
    20581 ttgtggagaa agagtttgga tatgacaaaa agtagaatca attggataga ttttggaaaa
    20641 ggcttttcca tatttttagt cttagcaggg catgtgttgc ttggactgta tcaatcggaa
    20701 aaatttccca cagcaaataa catactatcg ttgttgatag cacaagtcta catatttcat
    20761 ataccagtat tttttgcctt atcaggatac tttttcaaac ctgtgtcgga tttgaaggag
    20821 ttctggcaat atgctaaaaa gaagacaatt gtttttggtc tgccatatat tttctattcg
    20881 atcattcact ttggtcttca aaaagttgca ggggcatctg ttcgtgttcc tacaaccata
    20941 tctgatttgc taaatatcta taaagatcct cttggagttt cgtggtattt atatatactc
    21001 tggtcgattt tgataatcta tggattattg tctattttag tcaaaaatcg tagaatgtta
    21061 tttttgataa gtgttttcgc ttattgttta accctatttg ttcaaacaga tatttatatt
    21121 attcaaagaa cgctagtttg ggggatttgt ttctttcttg gcagtgtatt gagtgaaatt
    21181 cactttgata aaattaattt gaaaaaattt ctttttttct ttgtgttatt tgattttatt
    21241 tatatgttcg cttggttctt gttttatgaa gtagggtcta agaaggatta tgtaagctat
    21301 agtaacccag gtttgtgggg gattgctttt attgtctgtg tattagttgc ttttgcgatt
    21361 tttcctaaaa tggagaaaaa ttttcctaaa actttcctat atttcactaa atacgggaaa
    21421 gatagtttag ggatctatat tcttcatgca ccaatttgta gcatgattcg gattctaatg
    21481 ttgaaagtgg gaataaactc agtttttatt cacgttgttg ttgggattgt gctaggctgg
    21541 tatttatcca tactagcaac ttatatattg aaaaaaattc catttttgaa tattgtttta
    21601 ttaccacaaa agtatattaa attaaaataa attattttag atttataatg tggctctttg
    21661 tcaactaaca tctggagagg acaatcactg tcttctcttt ttttgtcttt tcagaatata
    21721 ccaaattaac acaaaaattc tgaaaattct attgacaact ttctgaaaag agtctataat
    21781 ggagagaaag ttttaaagga gaaaatgatg aaaagttcaa aactatttgc ccttgcgggc
    21841 gtgacattat tggcggcgac tactttagcc gcatgctctg gatcaggttc aagcgctaaa
    21901 ggtgagaaga cattctcata catttatgag acagaccctg ataacctcaa ctatttgaca
    21961 actgctaagg ctgcgacagc aaatattacc agtaacgtgg ttgatggttt gctagaaaat
    22021 gatcgctacg ggaactttgt gctgtctatg gctgaggatt ggtctgtatc taaggatgga
    22081 ttgacttaca cttatactat ccgtaaggat gcaaaatggt atacttctga aggtgaagaa
    22141 tacgcggcag tcaaagctca agac
//
