LOCUS       CR931696               25372 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 2813/41 (serotype 32a).
ACCESSION   CR931696
VERSION     CR931696.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25372)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 25372)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..25372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="2813/41"
                     /db_xref="taxon:1313"
     gene            <1..33
                     /gene="dexB"
                     /locus_tag="SPC32A_0001"
     CDS             <1..33
                     /gene="dexB"
                     /locus_tag="SPC32A_0001"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34112.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZU9"
                     /translation="PWDAFCVELL"
     gene            192..360
                     /gene="aliB"
                     /locus_tag="SPC32A_0002"
                     /pseudo
     CDS             192..360
                     /gene="aliB"
                     /locus_tag="SPC32A_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(361..1165)
                     /gene="tnp"
                     /locus_tag="SPC32A_0003"
                     /pseudo
     CDS             complement(join(361..795,794..1165))
                     /gene="tnp"
                     /locus_tag="SPC32A_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(793..795,794..1147))
                     /gene="tnp"
                     /locus_tag="SPC32A_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 3.9e-19"
                     /pseudo
     gene            complement(1562..2955)
                     /gene="tnp"
                     /locus_tag="SPC32A_0004"
                     /pseudo
     CDS             complement(join(1562..1696,1696..2955))
                     /gene="tnp"
                     /locus_tag="SPC32A_0004"
                     /note="member of homology group 17"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1202 transposase"
     misc_feature    complement(1969..2472)
                     /gene="tnp"
                     /locus_tag="SPC32A_0004"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 3.6e-20"
                     /pseudo
     gene            complement(3061..4014)
                     /gene="tnp"
                     /locus_tag="SPC32A_0005"
     CDS             complement(3061..4014)
                     /gene="tnp"
                     /locus_tag="SPC32A_0005"
                     /note="member of homology group 39"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1239 transposase"
                     /protein_id="CAI34116.1"
                     /db_xref="GOA:Q4K0X9"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="UniProtKB/TrEMBL:Q4K0X9"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     misc_feature    complement(3070..3507)
                     /gene="tnp"
                     /locus_tag="SPC32A_0005"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 6.6e-23"
     misc_feature    complement(3868..3933)
                     /gene="tnp"
                     /locus_tag="SPC32A_0005"
                     /note="Predicted helix-turn-helix motif with score
                     1087.000, SD 2.89 at aa 28-49, sequence
                     KSNREIAGLLGKAPQTIHNEVK"
     gene            4368..5822
                     /gene="wzg"
                     /locus_tag="SPC32A_0006"
     CDS             4368..5822
                     /gene="wzg"
                     /locus_tag="SPC32A_0006"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34117.1"
                     /db_xref="GOA:Q4JZS6"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JZS6"
                     /translation="MLIMSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNI
                     LAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGL
                     TNRLNATSNYSEYSISVAVLADSEIENVTQLMSVTAPTGTDNENIQKLLADIKSSQNT
                     DLTVNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKV
                     EAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPI
                     ADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVH
                     NDQEFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKL
                     TSTEALKNYGTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMGL
                     PSYAMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    4368..4493
                     /gene="wzg"
                     /locus_tag="SPC32A_0006"
                     /note="Signal peptide predicted for SPC1480 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 42 and 43"
     misc_feature    4581..4928
                     /gene="wzg"
                     /locus_tag="SPC32A_0006"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 2.7e-63"
     misc_feature    5106..5549
                     /gene="wzg"
                     /locus_tag="SPC32A_0006"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 5.7e-70"
     gene            5824..6555
                     /gene="wzh"
                     /locus_tag="SPC32A_0007"
     CDS             5824..6555
                     /gene="wzh"
                     /locus_tag="SPC32A_0007"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34118.1"
                     /db_xref="GOA:Q4JZS5"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZS5"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEKDLVHIIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    5827..6435
                     /gene="wzh"
                     /locus_tag="SPC32A_0007"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1.5e-36"
     gene            6561..7256
                     /gene="wzd"
                     /locus_tag="SPC32A_0008"
     CDS             6561..7256
                     /gene="wzd"
                     /locus_tag="SPC32A_0008"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34119.1"
                     /db_xref="GOA:Q4JZS4"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4JZS4"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSAFI
                     VKPEYTSTTRIYVVNRNQGDKSGLTNQDLQAGSYLVKDYREIILSQDVLEKVATNLKL
                     DMPAKTLTRKVQVTVPVDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDIRVKRPEDVEDVLQI
                     PLLGVVPDFDKMK"
     misc_feature    6561..6677
                     /gene="wzd"
                     /locus_tag="SPC32A_0008"
                     /note="Signal peptide predicted for SPC1482 by SignalP 2.0
                     HMM (Signal peptide probability 0.729) with cleavage site
                     probability 0.460 between residues 39 and 40"
     misc_feature    6582..6998
                     /gene="wzd"
                     /locus_tag="SPC32A_0008"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1.5e-56"
     misc_feature    7104..7181
                     /gene="wzd"
                     /locus_tag="SPC32A_0008"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            7266..7955
                     /gene="wze"
                     /locus_tag="SPC32A_0009"
     CDS             7266..7955
                     /gene="wze"
                     /locus_tag="SPC32A_0009"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34120.1"
                     /db_xref="GOA:Q4JZS3"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZS3"
                     /translation="MPTLEISQAKLDFVKKAEENYNALCTNLQLSGDDLKVFSITSVK
                     QGEGKSTTSTNIAWAFARAGYKTLLIDADIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            7970..9337
                     /gene="wchA"
                     /locus_tag="SPC32A_0010"
     CDS             7970..9337
                     /gene="wchA"
                     /locus_tag="SPC32A_0010"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34121.1"
                     /db_xref="GOA:Q4JZS2"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4JZS2"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRRYLIELVQTLKYILFFALAISISNFFLEDQFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKIVAEGEIVNFATHEVVDEVFIDLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKNGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     misc_feature    7970..8062
                     /gene="wchA"
                     /locus_tag="SPC32A_0010"
                     /note="Signal peptide predicted for SPC1484 by SignalP 2.0
                     HMM (Signal peptide probability 0.902) with cleavage site
                     probability 0.355 between residues 31 and 32"
     misc_feature    8753..9334
                     /gene="wchA"
                     /locus_tag="SPC32A_0010"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 4.4e-156"
     gene            9341..10555
                     /gene="wchF"
                     /locus_tag="SPC32A_0011"
     CDS             9341..10555
                     /gene="wchF"
                     /locus_tag="SPC32A_0011"
                     /note="member of homology group 15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34122.1"
                     /db_xref="GOA:Q4JZS1"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q4JZS1"
                     /translation="MPLSLVRREMKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGN
                     IQYYVACMRENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELAK
                     GNKDEAPIFYILACRIGPFISGLKKKIRSVGGRLLVNPDGHEWLRAKWSMPVRKYWKF
                     SEQLMVKHADLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDVKVRNW
                     YREKGVSENGYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKE
                     TGFDKDPRVKFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLD
                     VGFNREVGEDGAIYWKKDVGDLARLIDIVDRKDETFREKLGLMAKDRIETAYSWQFIE
                     KEYKEIWDEEAI"
     misc_feature    9986..10483
                     /gene="wchF"
                     /locus_tag="SPC32A_0011"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 0.00031"
     gene            10485..11570
                     /gene="wcyH"
                     /locus_tag="SPC32A_0012"
     CDS             10485..11570
                     /gene="wcyH"
                     /locus_tag="SPC32A_0012"
                     /note="member of homology group 178"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI34123.1"
                     /db_xref="GOA:Q4JZU1"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4JZU1"
                     /translation="MKQHIVGNSLKKSIRRFGMRKRYDNLDGLRVISCLGIIAMHIKA
                     NADYQIYGWIFEVFVPSLTLLVYLFLLISGFGMFCGYYERFKEGKIDLNNFYKKRYKK
                     IIPFFAFLIFIDILVERSFSHLIEGFTEATLVFGLLPNNQPDVIGVSWTIGVIFLFYM
                     LFPFFVWLCWDKKRAFISFIISVILNIFCEIYYFTDKFVIDSFASRHSFLYCSPFFLG
                     GGLIYMYRKEIKDFVSQRKLFCLLGCLGITGFHYLFIQPWFKMDNLGSLLLLLYLPWL
                     CYAISVDSIVLSNKVMKYFSKISLELYLAHMVLFRVVEKMNFLYFFGKGWLSFILVFV
                     AVLIGLILLIEFLKKMTSFSRRLLIKE"
     misc_feature    10485..10622
                     /gene="wcyH"
                     /locus_tag="SPC32A_0012"
                     /note="Signal peptide predicted for SPC1486 by SignalP 2.0
                     HMM (Signal peptide probability 0.823) with cleavage site
                     probability 0.803 between residues 46 and 47"
     misc_feature    10551..11546
                     /gene="wcyH"
                     /locus_tag="SPC32A_0012"
                     /note="HMMPfam hit to PF01757, Acyltransferase family,
                     score 7.2e-06"
     gene            11751..12986
                     /gene="wzy"
                     /locus_tag="SPC32A_0013"
     CDS             11751..12986
                     /gene="wzy"
                     /locus_tag="SPC32A_0013"
                     /note="member of homology group 179"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase Wzy"
                     /protein_id="CAI34124.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR9"
                     /translation="MDMNKITIRELIILFVLILFIFQNLLEKYFVYAQYIDEIVALLF
                     LIHYFLRVVLNKSISKKFSRLVLLLLTIILITLISNFWNNVQTNILIISIDLFSIFKF
                     IFIFLGAQSFLNDLTHKEIKRIILRVYFISNIYLSVLIVLAFLNIFIGLGMHQEYRYG
                     LPTFSFIFGTPGQVINLSIIFLLLYQLNKLYNSKNNLIHLVLIFLLLLSTLKTRAIVL
                     AIVFVYILYLFEIRNISSMKKRVLPVLGLGAVVGFEQFKTYFLTSDTPRLTLFKYGML
                     TMRRYFPLGSGFATYGSDIAAKNYSLLYYQYGFHNRYGMNPYDIRFLNDNFYPMIFAQ
                     FGFLGGILYVFLLLDYFRLLLRVASINDKVIKTSVFIYIFNVVLSSIQSSYPGTNSMV
                     ITTFLICLILRYSDKWRIL"
     gene            12971..13681
                     /gene="wcyI"
                     /locus_tag="SPC32A_0014"
     CDS             12971..13681
                     /gene="wcyI"
                     /locus_tag="SPC32A_0014"
                     /note="member of homology group 180"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAI34125.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR8"
                     /translation="MEDFMIIEAIGLPGSGKTFLFHELEKEFRSNSIRTYNFTELSRN
                     NISVKIVVKLLLKFVSLKYICKKWKKELYDILSEELPYESKFDLYENPDYCVNYALML
                     LFIYRLFQNSKIVLLLDEGMYHNIVKLCADFDFSIRLSNKLIEKCVLLSRLNDSKHIV
                     IYNIFPISETLLSIEKRNRHVSKFDELETTQLSKILDNYDKLNNAIYNNDKKQIISVF
                     RKDFIEKNISYIKQNLNI"
     gene            13759..14637
                     /gene="wchQ"
                     /locus_tag="SPC32A_0015"
     CDS             13759..14637
                     /gene="wchQ"
                     /locus_tag="SPC32A_0015"
                     /note="member of homology group 43"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34126.1"
                     /db_xref="GOA:Q4JZR7"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR7"
                     /translation="MVIFVVLHYMVFKETKQCVNSIKNNVKGEKKIIIVDNCSPNGSY
                     SSLVDAFGCDKDIIIMKSDSNLGFARGNNLGYKYAVENFNPDFIVVMNNDMEIFQEDF
                     IDKLYESYAKYGYYILGPDIYSTKQEYHQNPQTRKVLDRSDLKLLYRKLVIKDRLRFL
                     VPVKWWFKNILIKNKSVDNNSKDKNEYVQNIVKNPLLHGSCYVFSKKFTEKHQHTCFY
                     DKTFMYMEAEILHYMALKNNELMLYYPDLKVYHHEDVATDSTFVKQYKKSFFSIRCLL
                     QSTKAFIDLIDSDKKE"
     misc_feature    13765..14259
                     /gene="wchQ"
                     /locus_tag="SPC32A_0015"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 7.8e-15"
     gene            14641..16101
                     /gene="wzx"
                     /locus_tag="SPC32A_0016"
     CDS             14641..16101
                     /gene="wzx"
                     /locus_tag="SPC32A_0016"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase Wzx"
                     /protein_id="CAI34127.1"
                     /db_xref="GOA:Q4JZR6"
                     /db_xref="InterPro:IPR002528"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR6"
                     /translation="MESQKKSVEKNYIYNLIYQMLTVVIPIIITPYISRVLNADGIGI
                     FSYTTAVVGYFVLLGNLGIATYGQLQVAKYQEDRFKLSKIFFELLILRTILLLLVLLI
                     YLVFIQFQDIIYKSIYYVLIIQILCSLLDISWFLQGLEEFKSIVMRNTLIKVLSVISI
                     LIFVKKDTDLILYALIMNASTLLGNISIFAYVPKYVQRVKLAEINLLKHISHCLVYFI
                     PTIATTIYLTLDKTMIGWFSLNTFENGYYEQAQKIEQMVVTIVTSLSVVTMPRMTYLL
                     NNNQFQEFKVRLEQSIRFILFLSLPMSLGLVGIANNFIPLFLGVGFEKSISILKIFSL
                     LVIIIGLNNALGKQILMPSGQQRAYNISVVIGAVINIVFNLILIPQFFSLGAAISSVL
                     AEFAILIIFLYYSRNCIPPKWVIRTAVKYLGSSIVMFLIIRTIELLSPPSWTVVIIQV
                     IVGVAVYILSLYILKDQIVRKYYLRLRKLNVLARKV"
     misc_feature    14662..15468
                     /gene="wzx"
                     /locus_tag="SPC32A_0016"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.7e-44"
     gene            16141..17097
                     /gene="wcyS"
                     /locus_tag="SPC32A_0017"
     CDS             16141..17097
                     /gene="wcyS"
                     /locus_tag="SPC32A_0017"
                     /note="member of homology group 118"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34128.1"
                     /db_xref="GOA:Q4JZR5"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR5"
                     /translation="MSIFSTLIKKKGAEIFKDLIQSRVLFRTIAILPLVGFSKKSLEI
                     VRLNNSNVVLSKLRRKYKQTIKNLDREKQYSLSYNQRHKDASNKIWICWFQGLDTAPH
                     VVQECIASVKKHLADREVVVLTDENYHQYVTFPDYIKEKATQGFISKAHFADLLRLEL
                     LTEYGGTWIDGTIFCSSSDIPAYMLDSDLFLFQNLKPGLDGQALAISNWFITASYSNH
                     PLLNMTKDLLYDYWKNHNGVVDYFIFHHFFQLSIEEFPEYWSKVVPFNNSTPHILQLR
                     LFEEFDEVMYGYILEQTPFHKLTYKFEEEKSRIPNTYYKHLF"
     misc_feature    16276..17091
                     /gene="wcyS"
                     /locus_tag="SPC32A_0017"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 3.3e-69"
     gene            17173..17994
                     /gene="wcrN"
                     /locus_tag="SPC32A_0018"
     CDS             17173..17994
                     /gene="wcrN"
                     /locus_tag="SPC32A_0018"
                     /note="member of homology group 119"
                     /codon_start=1
                     /transl_table=11
                     /product="putative LicD-family phosphotransferase"
                     /protein_id="CAI34129.1"
                     /db_xref="GOA:Q4JZR4"
                     /db_xref="InterPro:IPR007074"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR4"
                     /translation="MKELTTREMQEVSLEILHTIASICEKHHFRYALIYGTLIGAVRH
                     KGYIPWDDDVDIMMPRPDYDRLLEYLKENIADYPHLKVFNREECPEYPYMITRISDQR
                     YRIEMENEKPFDLGVFIDIYPYDGLGDTKEEAVDFGMKGDRLSSFCYQATREHFAIET
                     TTSTFRKLIKYPVYLFSKMIGKDYFQKQLAKLARVKDYDNSEYVGCVIWLSWGEKDIF
                     PREWFDETILVPFEKYEFRIPKEFDKVLRHEYGDYMILPPEKDRVGHHYFKAYKK"
     misc_feature    17242..17925
                     /gene="wcrN"
                     /locus_tag="SPC32A_0018"
                     /note="HMMPfam hit to PF04991, LICD Protein Family, score
                     2.5e-45"
     gene            18159..18428
                     /gene="HG271"
                     /locus_tag="SPC32A_0019"
                     /pseudo
     CDS             18159..18428
                     /gene="HG271"
                     /locus_tag="SPC32A_0019"
                     /note="member of homology group 271"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative transferase (pseudogene)"
     misc_feature    18162..18215
                     /gene="HG271"
                     /locus_tag="SPC32A_0019"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 0.13"
                     /pseudo
     misc_feature    18249..18302
                     /gene="HG271"
                     /locus_tag="SPC32A_0019"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 0.26"
                     /pseudo
     misc_feature    18303..18356
                     /gene="HG271"
                     /locus_tag="SPC32A_0019"
                     /note="HMMPfam hit to PF00132, Bacterial transferase
                     hexapeptide (three rep, score 0.032"
                     /pseudo
     gene            18898..19767
                     /gene="rmlA"
                     /locus_tag="SPC32A_0020"
     CDS             18898..19767
                     /gene="rmlA"
                     /locus_tag="SPC32A_0020"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI34131.1"
                     /db_xref="GOA:Q4JZR3"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR3"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSINPSPRGELEITDVNKAYLDRGGLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISKEQVHELAQPLKKN
                     EYGQYLLRLIGEV"
     misc_feature    18901..19617
                     /gene="rmlA"
                     /locus_tag="SPC32A_0020"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 3.3e-118"
     gene            19768..20364
                     /gene="rmlC"
                     /locus_tag="SPC32A_0021"
     CDS             19768..20364
                     /gene="rmlC"
                     /locus_tag="SPC32A_0021"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI34132.1"
                     /db_xref="GOA:Q4JZR2"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q4JZR2"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGKTYQTVIDASKGIFVPRGVANGFQVLSDTASYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     misc_feature    19804..20334
                     /gene="rmlC"
                     /locus_tag="SPC32A_0021"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 3e-16"
     gene            20374..21423
                     /gene="rmlB"
                     /locus_tag="SPC32A_0022"
     CDS             20374..21423
                     /gene="rmlB"
                     /locus_tag="SPC32A_0022"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI34133.1"
                     /db_xref="GOA:O54546"
                     /db_xref="HSSP:1KEP"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:O54546"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    20389..21345
                     /gene="rmlB"
                     /locus_tag="SPC32A_0022"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00012"
     misc_feature    20392..21132
                     /gene="rmlB"
                     /locus_tag="SPC32A_0022"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 5.4e-77"
     misc_feature    20395..21207
                     /gene="rmlB"
                     /locus_tag="SPC32A_0022"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/iso, score 1.4e-05"
     gene            21489..22340
                     /gene="rmlD"
                     /locus_tag="SPC32A_0023"
     CDS             21489..22340
                     /gene="rmlD"
                     /locus_tag="SPC32A_0023"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI34134.1"
                     /db_xref="GOA:Q4K1G6"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1G6"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    21489..22337
                     /gene="rmlD"
                     /locus_tag="SPC32A_0023"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 4e-147"
     misc_feature    21492..22121
                     /gene="rmlD"
                     /locus_tag="SPC32A_0023"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.9e-19"
     misc_feature    21492..22133
                     /gene="rmlD"
                     /locus_tag="SPC32A_0023"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00013"
     misc_feature    21495..22223
                     /gene="rmlD"
                     /locus_tag="SPC32A_0023"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2.9e-08"
     gene            order(22416..23369,23380..23601)
                     /gene="tnp"
                     /locus_tag="SPC32A_0024"
                     /pseudo
     CDS             join(22416..23369,23380..23601)
                     /gene="tnp"
                     /locus_tag="SPC32A_0024"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     misc_feature    22422..22865
                     /gene="tnp"
                     /locus_tag="SPC32A_0024"
                     /note="HMMPfam hit to PF03050, Transposase IS66 family,
                     score 6e-05"
                     /pseudo
     gene            complement(23698..24954)
                     /gene="tnp"
                     /locus_tag="SPC32A_0025"
     CDS             complement(23698..24954)
                     /gene="tnp"
                     /locus_tag="SPC32A_0025"
                     /note="member of homology group 13"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
                     /protein_id="CAI34136.1"
                     /db_xref="GOA:Q4JZQ9"
                     /db_xref="InterPro:IPR002560"
                     /db_xref="InterPro:IPR012287"
                     /db_xref="UniProtKB/TrEMBL:Q4JZQ9"
                     /translation="MEQLHLITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSQA"
     misc_feature    complement(24202..24498)
                     /gene="tnp"
                     /locus_tag="SPC32A_0025"
                     /note="HMMPfam hit to PF01610, Transposase, score 5e-48"
     misc_feature    complement(24538..24603)
                     /gene="tnp"
                     /locus_tag="SPC32A_0025"
                     /note="Predicted helix-turn-helix motif with score
                     1691.000, SD 4.95 at aa 118-139, sequence
                     ISMTDIAHQLAISTSTVIRKLN"
     gene            25220..>25372
                     /gene="aliA"
                     /locus_tag="SPC32A_0026"
     CDS             25220..>25372
                     /gene="aliA"
                     /locus_tag="SPC32A_0026"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34137.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K0S2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYL"
     misc_feature    25220..25306
                     /gene="aliA"
                     /locus_tag="SPC32A_0026"
                     /note="Signal peptide predicted for SPC1500 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
BASE COUNT     7922 a   3964 c   5169 g   8317 t
ORIGIN
        1 ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa atttaaaatt
       61 gaaatcgtat aaaaacaagg gaggactgta taaaaggcag aaatcctttg ttttttataa
      121 ccaaggttta taaaccttca ttctcgaaat tcaattaact ttacaaattc ccactattaa
      181 ggagaaagaa gacgaacata aagaagcgta tccttagtgc aggcctgact tttacatctg
      241 ctttgctttt agctgcttgc gaccaatcag gttcagatac aaaaacttac tcatcaacct
      301 ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat aatatagtca
      361 attgaaacaa gaacaagaca aaagagccca tgttttctca ataggattgt actcaggtga
      421 atagggagga agaggtaaaa gtttatgccc aaactcttca cacaagagtt ctagcttccc
      481 cattctatgg aatcttgcat tatccataat aataaccgat ggtgtggtta atgttggtaa
      541 gagaaatttc tgaaaccaag cttcaaaaaa gtcgctcgtc atcgtctctt cgtaagtcat
      601 tggagcgatt aactcaccat ttgttagacc tgcaaccaaa gaaatcctct gatatcttct
      661 tccagatact ttgcctcttc ttaactgacc ttttaaagag cgaccatgtt ctcgataaaa
      721 ataagtatcg aatcctgttt cgtcaatcta aacaggtgct aggtgcttta atctattaaa
      781 attcttaaga aataaggcta ctttttctgg gtcttgttca tagtaagtgt ggttcttttt
      841 ttcgagtgta gcccatagct ttgagcgcat agtggatggt agttggatga cagccaaatt
      901 cagaagctat ttcagtcaaa taagcgtctg gattgtcagt aagatagttt ttaagtctat
      961 ctctatcaac ttttcttggt tttgttcctt ttacttggtg gtttagctct cctgtttttt
     1021 cttttagctt taaccagcca taaatggtat tacgtgagat ttggaaaacg tgtgatgctt
     1081 ctgttatact acctattcgc tcacaataag agagaacttt tttacgaaaa tctattgaat
     1141 atgccataaa aagattatac cacattgtgt actatattat attgaaacta gaatagtaca
     1201 catctgcttc taaaatattg ttagaaaacg atttgactgt cctgatcaat ttgtcatgtt
     1261 cttatttcat tttactatat tttgctactc cccgtaaagt gtcaatcgaa agtgattatg
     1321 tcccaaaaaa atggagatat tgaggtcaat tattttgatt tcatttgaca cgaggaaccc
     1381 ttgaagctgt tttgccagct aaaccaaggc tagtcttagc cttggctcgc cagcctaaca
     1441 gctccaagcc tcgtgtcaaa tgaaatgctt gtcttacact ccttactttc tcgctcctaa
     1501 atgtaaggga tagagtgatt tcctttaagg aaaagcttcc catttagcga gaaatagatt
     1561 agacttgtag atgaggagaa tcaagctcct cactagtaaa ctcttcataa tcctttttat
     1621 ttttatgaag gtattgtttg aaagatgtga atttccacgg atgggtttgt ggagggatat
     1681 acttgcgtct ttcttttttt gttctggttc ttgttcaaag tttttcgaat agagttcatg
     1741 aactagtagc tcctttgtgt gatagatttt gtcagcgata ttgaggtaga tgtcaccatc
     1801 aaatgctttt ataactaatg ctttcgtctt tctgctgaaa tagacttctt ttccttgttc
     1861 ggtagggata tagcaacgat tttggaagcg gatatggtgt ccactatcga cgactctctc
     1921 cgccagtcta gccagaatga gatttcgttc agagggctta ggagccttct caaagacaga
     1981 gagttttgtc ttgtttccaa actgttcatt aaaggtttgg atgtaggaaa gcaggaaggt
     2041 attggcttct tccaaggtat gaatcttgtt tcgttccagt tcgataggca ggcgagattg
     2101 tagtgtctga ttgagtcttt cgactctccc tttagcttga gggatagagg ttgtctccag
     2161 aagaatcccc agttggtgac aggcgtatcc gaattgtgta tgggtatcgt cctccatttt
     2221 cttagagttg gagatttgat aggtaaagac tgttttttta tctgttttga tttgaagggg
     2281 aatgccgtgg ttgtctaaaa tttgttcgag gacatgatag taagcattca aggtctcttg
     2341 tttatcaaaa taagcgccta ggatattgcc agaagcatca tcaatggcta ggtgtaagtt
     2401 agaggtttgg gctccaaacc aggcatgagg gctggcatcc atttggatga gttctccagc
     2461 aaatttcttt ctgagtctac taggatgtac ttttttaggg tcttcaagga aattttcagc
     2521 tgtcggtaag attggcttgt ctaggggttg cttggggttc agtttagctt gttttcttag
     2581 tctcttcttt gtctttctat gggacttagg cgacaggata ttttccttat agagtatttt
     2641 tctaacagtt gtatcagaga gctgaattcc ttcttcttca gctagcaatt cacagaaatg
     2701 acggacattt ggtttatatg ttttatagga gaggtatttc tttaggatac gttctttgat
     2761 ttcatcaggg attgcatgtt ttggttttcg atttctgttt ccgtgtctga aggcttcttt
     2821 tcctttcagt tgatagacca gtagtagacg attgatttgc ctttcagaaa gattgagttc
     2881 ggcacaggct cgtttctttg ttttctttcc ttgggctata gcttttatca caagatattt
     2941 tttcatttca ttcatattta gttggatcct tttcatatga ctattctacc aaatgggaca
     3001 ttttcacgtt cgatttacta aagacattat cacattcgaa tcccaaattt caagttgaag
     3061 ttagccaccc aaaagaaatt cacttggcga cttgtagtcc aagcattttt tagggtagtt
     3121 gttaatccaa ttttcgataa aagctacttc tttcggagtc gttttcttgg ttcctttagg
     3181 taaccatctc cgaattaatc gattatgatt ttcatttgaa cctctctccc atgaagagta
     3241 agcatgtgcg tagtagatat gttcctcagg aaatacctca gacaatcgtt tgaactccga
     3301 accattatct gcagtaatgg acagaatacg atgctcccct aatagtaacg taagcgcctg
     3361 attgacagat tcagcagttt tatttggaat taaccttata atttggtgtc tgctccgccg
     3421 gtcggttaag actaacaggc aataattttt tatcttagtc agtaggacgg tatcaatttc
     3481 ataatgacca ttttccaagc gaagattaat aacgtcagga cgttcttcga tagatttacc
     3541 tgccggctta aagttcggac tagcttgctt cttgacacct ttcctttttc tgggataaag
     3601 catgtcggcc ttcgtcaatc ctaaatgacc attatgaaac cagtagtaga tggttgaaat
     3661 accaactttc acttgcttct tgttaaccat catttcaggc gaaaattttt gcttatgata
     3721 gtgtaagatc ttctctctga tttcctttgt taaaattaac tttttcaccg accgttttcg
     3781 attgaattgg taaacagttt gtgcgtaatc ggcagaatag acctttttgt atagcccttt
     3841 tctcacttgt tgtaaagttg tacctctttt gacttcatta tgaatcgttt gaggcgcctt
     3901 tcctaacaag cctgcaattt cacgattgga cttattttca ttcttccacc gctcaatcaa
     3961 gcgacggtta tctattgtca aatgtttccc ttttggggta taatgttctt gcatctctgt
     4021 gcctttcctt gtgtttgtgg tgaacaacaa gtatagcaca gaggtgtttt cttatacctt
     4081 aaatcacatt tcatttgaca acaggaaccc ttgaacctgt tttttcagct aaaccaaggc
     4141 tatgattagc cttggccacc tagcctaaca gtttcaaacc tgttatcaaa tgaaatcatc
     4201 aacttactca aacatagtga aacatctaat tcttgactaa ggtaaggtgg ctaacttcat
     4261 tatagaactt tcaatcacat tcgaatcaca taaagatgca gatagtaaaa aaagatgtag
     4321 acattaccgt aaaaaagtga tataattgta cgatgttcaa ggtataggtg ttaatcatga
     4381 gtagacgttt taaaaaatca cgttcacaga aagtgaagcg aagtgttaat atcgttttgc
     4441 tgactattta tttattgtta gtttgttttt tattgttctt aatctttaag tacaatatcc
     4501 ttgcttttag atatcttaat ctagtggtaa ctgcgttagt cctactagtt gccttggtag
     4561 ggctactctt gattatctat aaaaaagctg aaaagtttac tatttttctg ttggtgttct
     4621 ctatccttgt cagctctgtg tcgctctttg cagtacagca gtttgttgga ctgaccaatc
     4681 gtttaaatgc gacttctaat tactcagaat attcaatcag tgtcgctgtt ttagcagata
     4741 gtgagatcga aaatgttacg caactgatga gtgtgacagc accgactggg actgataatg
     4801 aaaatattca aaaactacta gctgatatca agtcaagtca gaataccgat ttgacggtta
     4861 accagagttc gtcttacttg gcagcttaca agagtttgat tgcaggggag actaaggcca
     4921 ttgtcctaaa tagtgtcttt gaaaacatca tcgagtcaga gtatccagac tacgcatcga
     4981 agataaaaaa gatttatacc aagggattca ctaaaaaagt agaagctcct aagacgtcta
     5041 agaatcagtc tttcaatatc tatgttagtg gaattgacac ctatggtcct attagttcgg
     5101 tgtcgcgatc agatgtcaat atcctgatga ctgtcaatcg agataccaag aaaatcctct
     5161 tgaccacaac gccacgtgat gcctatgtac caatcgcaga tggtggaaat aatcaaaaag
     5221 ataaattaac ccatgcgggc atttatggag ttgattcgtc cattcacacc ttagaaaatc
     5281 tctatggagt ggatatcaat tactatgtgc gattgaactt cacttctttc ttgaaaatga
     5341 ttgacttatt gggaggggta gatgttcata atgatcaaga gttttcagct ctacatggga
     5401 agttccattt cccagtaggg aatgtccatc tagactctga gcaggctcta ggttttgtac
     5461 gtgaacgcta ctcactagcc gatggagacc gtgaccgtgg tcgcaaccaa caaaaggtga
     5521 ttgtggctat ccttcaaaaa ttaacgtcaa ccgaagcact gaaaaattat ggtacgatca
     5581 ttaatagctt gcaagattct atccaaacaa atatgccact tgagaccatg ataaatttgg
     5641 tcaatgctca gttagaaagt ggagggaatt ataaagtaaa ttctcaagat ttaaaaggta
     5701 caggtcgaat gggtcttcct tcttatgcaa tgccagacag taacctctat gtgatggaaa
     5761 tagatgatag tagtttagct gtagttaaag cagctataca ggatgtgatg gagggtagat
     5821 gaaatgatag acatccattc gcatatcgtt tttgatgtag atgatggtcc caagtcaaga
     5881 gaggaaagca aggctctctt ggcagaatcc tacaggcagg gggtgagaac cattgtctct
     5941 acctctcacc gtcgcaaggg catgtttgaa actccggaag agaagatagc agaaaacttt
     6001 cttcaggttc gggaaatagc taaggaagtg gcgagtgact tggtcattgc ttacggggct
     6061 gaaatttact acacaccaga tgttctggat aagctagaaa aaaagcggat tccgaccctc
     6121 aatgatagtc gttatgcctt gatagagttt agtatgaaca ctccttatcg cgatattcat
     6181 agcgccttga gcaagatctt gatgttggga attactccag tcattgccca cattgagcgc
     6241 tatgatgctc ttgaaaataa tgaaaaacgc gttcgggagc tgattgatat gggctgttac
     6301 acgcaagtaa atagttcaca tgtcctcaaa cccaaacttt ttggcgaacg ttataaattc
     6361 atgaaaaaaa gagctcagta ttttttagag aaagatttgg ttcatatcat tgcaagtgat
     6421 atgcacaatc tagacggtag acctcctcat atggcagaag catatgacct tgttacccaa
     6481 aaatacggag aagcgaaggc tcaggaactt tttatagaca atcctcgaaa aattgtaatg
     6541 gatcaactaa tttaggagaa atgatgaaag aacaaaacac gatagaaatc gatgtatttc
     6601 aattatttaa aaccttgtgg aaacgcaagc taatgatttt attagtggca cttgtgacag
     6661 gtgcgggggc ttttgcatat agcgctttta ttgttaagcc agaatatacg agtaccacgc
     6721 gaatttacgt agtgaatcgc aatcaaggag acaagtcggg gctgacaaat caggatttgc
     6781 aggcaggatc ttatctggta aaagactacc gtgagattat cctttcgcag gatgtattgg
     6841 aaaaagtagc gacaaatttg aagttggata tgccagccaa aacgttaacc agaaaagttc
     6901 aagtgactgt accagttgac actcgtatcg tctcaatctc tgtcaaggat aaacagccag
     6961 aggaagccag tcgtatcgct aattctctac gagaagttgc tgcagaaaag atcgtcgctg
     7021 taacgcgagt atctgatgta acgacacttg aagaagcgcg accagctacg accccctctt
     7081 ctccaaatgt tcgacgcaat tccttgtttg gttttcttgg aggagcagtc gtaacagtaa
     7141 ttgctgttct tttgattgag ttgctcgaca tccgtgtgaa acgtcctgaa gatgtcgaag
     7201 acgtactgca aattccactt ttaggggtcg ttccagattt tgacaaaatg aaataggagg
     7261 aaattatgcc aacattagaa atctcacagg caaaattgga ttttgtaaaa aaggcagagg
     7321 aaaattataa cgctttgtgc acgaacctac agttaagtgg agatgatttg aaagtatttt
     7381 ctatcacttc tgtgaaacaa ggagaaggaa aatcaacgac ttccaccaat atcgcttggg
     7441 cttttgcgcg tgcaggttac aaaacgctgc tgattgatgc agatattcgc aattctgtta
     7501 tgttaggtgt ctttaaagca agggataaga ttacaggcct gacagaattt ttatcaggaa
     7561 ctacagacct atcacaaggg ctttgtgata ccaatatcga aaatctcttt gtaattcagg
     7621 ctggctctgt gtcaccgaat ccgacagctc ttcttcaaag taagaatttc agtacaatgc
     7681 ttgaaacctt gcgtaaatat tttgactaca tcattgtaga tactgctcct gtcggtgtcg
     7741 tgattgatgc ggctattatt acgcgaaaat gcgatgcttc tattttagtg acggaggcag
     7801 gtgaaataaa tcgacgggat attcaaaaag caaaagaaca gttggaacac acagggaagc
     7861 cgtttttggg agttgtgttg aataaattcg atacttcagt agacaaatac ggttcttatg
     7921 gaaattatgg agattacggg aaaaataaaa aataggtcgg gggatagaga tgaacggaaa
     7981 aatagtaaag tcttcattgg ccataatcca gagttttctt gttattttat tgacttatct
     8041 acttagtgct gtgagagaag cggagattgt ttcaacaaca gctattgcac tttatatcct
     8101 ccattatttt gtcttttata tcagtgatta tggacaggat ttctttaaaa ggagatattt
     8161 gattgaactt gtccagacat tgaaatatat cctattcttt gcactagcga ttagtatttc
     8221 taattttttc ttagaggatc aatttagtat ttccagacga ggcatgattt acttcctcac
     8281 attacatgct ctcttagtct atgtgctaaa cctatttatc aagtggtatt ggaagcgggc
     8341 ttatcccaac tttaaaggaa gtaagaagat tctcctactt acagcaactt ctcgtgtcga
     8401 aaaggtactg gatagattaa tagaatcaaa tgaggttgtt ggggagttgg tagccgtcag
     8461 tgtcttagat aaaccagatt ttcagcatga ttgtttaaag atagtagcag agggggagat
     8521 agtaaacttt gcgactcatg aggtggtcga tgaagtcttt atcgatcttc caagtgaaaa
     8581 atacaatatt ggagagcttg tctctcagtt tgaaacgatg ggaattgatg taacagttaa
     8641 tctaaatgct tttgatcgta gtttggcacg taacaagcaa attcgtgaga tggcaggatt
     8701 aaacgttgtg actttttcta caacatttta taagactagc catgtaattg ctaagcggat
     8761 tattgatatt atgggtgcat tggtagggct gatactatgt ggtttagtca gtattgtact
     8821 ggttcctttg attcgaaagg atgggggctc tgctattttt gctcagacgc gtataggaaa
     8881 aaatggtcgt cagtttactt tttataagtt tcgctctatg tgtgtagatg ccgaggcgaa
     8941 aaaaagagaa ctcatggaac aaaataccat gcagggtgga atgtttaagg tggacgatga
     9001 tcctcgtatc acgaaaaatg gtcgttttat acggaagact agcttggacg agctaccaca
     9061 gttttataat gttctaaagg gagatatgag tttggttggc acacggccac caacagtgga
     9121 cgagtatgaa cactataccc cagaacaaaa acgtcggcta agttttaaac ctggtataac
     9181 aggcttatgg caggtcagtg gacgaagtga gattaagaat tttgatgaag ttgtcaaatt
     9241 agatgtagcc tatatagacg attggacaat ttggaaagac attgaaattt tattgaagac
     9301 agttaaagtt gtattgatga aagatggagc gaagtgattt ttgcccctca gtcttgttag
     9361 gagagagatg aaacagtcag tttatatcat tggttcaaag gggattcctg ccaagtatgg
     9421 aggatttgaa acctttgttg agaaattaac agaatatcaa aaagatggta acatccaata
     9481 ctatgttgcc tgcatgcgcg aaaattctgc aaagtcagga tttacagcag atacatttga
     9541 gtacaacggt gctatttgtt acaacattga tgtgcctaat attggtcctg ctagagccat
     9601 cgcttacgat attgcagcgg tcaataaggc tattgaattg gctaagggaa acaaggacga
     9661 ggctcccatt ttttacattc tagcttgtcg tatcggacct tttatttctg gacttaagaa
     9721 aaaaattcgt tcggtcggag gccgtttact ggtaaatcca gatggccatg agtggcttcg
     9781 ggctaaatgg agcatgccag ttcggaagta ttggaaattt tcggaacagt tgatggtcaa
     9841 gcatgcagat ttattagtct gtgatagcaa aaatatcgaa aaatatatcc gagaggacta
     9901 taaacagtat cagcccaaga cgacctatat tgcttatggt acagatacta ccccttcaag
     9961 tctaaaatca gaagatgtca aagttcgaaa ctggtatcgt gaaaagggag taagcgaaaa
    10021 tggctattat ctagtggtgg gacgattcgt tcccgaaaac aactatgaaa ccatgattcg
    10081 tgaatttatc aagtctaagt ccaataagga ctttgtcctt attacaaatg tggagcaaaa
    10141 taaattttac gatcagttgc tgaaggaaac aggtttcgac aaggatccaa gagtcaaatt
    10201 tgtgggaaca gtctatgacc aagaattgct caaatacatc cgagagaatg cttttgctta
    10261 cttccatggc catgaagttg gtgggacaaa cccatcgctt ttagaagccc ttgcatcaac
    10321 aaaactaaat ttgttactag atgttggttt taaccgtgaa gttggtgagg atggagctat
    10381 ttattggaaa aaagatgttg gtgatttagc cagattaatt gacattgttg acagaaagga
    10441 tgagacgttt cgggaaaagc ttggcttaat ggcgaaagat agaattgaaa cagcatatag
    10501 ttggcaattc attgaaaaag agtataagga gatttgggat gaggaagcga tatgataatt
    10561 tggatggatt acgagtaatt tcttgtctgg gtataatagc gatgcatatt aaagctaatg
    10621 ctgactatca aatttatggt tggatatttg aagtgttcgt accgtcttta acgttgcttg
    10681 tctatttatt cttacttatt agtgggtttg gaatgttttg tggctattac gagcgattta
    10741 aagaaggaaa aattgatcta aataattttt ataaaaaaag gtataaaaag attatcccat
    10801 tttttgcttt tttgattttt atagatattt tagtagaacg aagtttttcg catttgattg
    10861 aaggatttac tgaagctaca cttgtcttcg gccttctgcc gaataatcaa ccggatgtta
    10921 ttggtgttag ctggacgatt ggggttattt tccttttcta tatgcttttt cctttttttg
    10981 tatggctatg ctgggataaa aagagggcgt ttattagttt tataatttca gttatattga
    11041 atatattttg tgagatatat tacttcactg ataagtttgt tatagattcg tttgcgtcgc
    11101 gtcatagttt tttatactgc tccccgttct ttcttggagg tggcctcatt tatatgtaca
    11161 gaaaggaaat aaaagatttt gtttcgcaac gtaaattgtt ctgcttactt ggttgtttag
    11221 gtattacagg tttccattat ctattcattc aaccttggtt taaaatggat aatttaggat
    11281 ctttattgtt acttctttac cttccatggc tttgctatgc tataagcgtt gatagtatag
    11341 ttcttagtaa caaagtaatg aaatatttta gtaaaattag cttagaactt tatttagcgc
    11401 atatggtact ttttcgagtt gttgagaaaa tgaatttctt atattttttt ggtaaaggct
    11461 ggcttagctt catattagtt tttgtagctg ttcttattgg attgatttta ttgattgaat
    11521 ttttgaaaaa gatgacaagt ttttctagga gattgctaat aaaggagtaa tttaagtggt
    11581 gtgatgtcat caagatttaa gttaaagaga atataggttg atagaaaaaa tatttccttt
    11641 ttctaaagtg tggattacaa atgctacttt ttgtaaacta attaataaat ttctatagca
    11701 ctaatatata ttacctctaa gaaaatgatg gaaagtgtgg aaaattaaac ttggatatga
    11761 acaaaattac aataagagaa ttgataatac tatttgtgtt aattcttttt atatttcaaa
    11821 atcttttaga aaagtatttt gtatatgctc agtatattga tgaaatagtt gcattattat
    11881 ttctcattca ttacttttta agagtagtgt taaataagag tatttcaaaa aaattttccc
    11941 gacttgttct tcttttatta actatcatat taattacttt aatttcaaat ttttggaata
    12001 atgtgcaaac taatatttta attatctcca ttgatttatt tagtattttt aaatttattt
    12061 ttatattttt gggggcacaa tcttttctca atgacttaac gcataaagaa ataaaaagaa
    12121 taattttacg agtttacttt attagtaata tatacttatc tgttttgatt gtcttagcat
    12181 ttttaaatat ttttataggc ttaggaatgc atcaagaata tcgctatggt ttaccaactt
    12241 tttcttttat ttttggtacg ccaggtcaag taattaatct ctcgattata ttcttacttc
    12301 tatatcagtt aaataaactt tataattcta aaaataatct cattcattta gtattaattt
    12361 ttttattact gctgtctaca ttaaaaacac gggcaattgt cttagcaatt gtgtttgtct
    12421 atattctcta tctatttgaa atacgaaata tttcatcaat gaaaaagaga gtacttcctg
    12481 ttctaggctt gggagcagtg gttgggtttg aacaatttaa aacttatttt ttgacttctg
    12541 atactccaag gctcacatta tttaaatacg gtatgcttac aatgagacgc tattttcctc
    12601 tgggaagtgg ttttgctaca tatggatccg atattgctgc taaaaactat tctctgttat
    12661 attatcaata tggatttcat aacagatatg gaatgaatcc atatgatatt agatttttaa
    12721 atgataattt ttatccaatg atttttgcac aatttggatt tttaggagga atactttatg
    12781 tatttctact attagattat tttagattat tattacgtgt tgcaagtata aatgataagg
    12841 ttattaaaac ttcagtattt atttatatct ttaatgttgt cttatcgtct attcaatcat
    12901 cttatccggg aacgaattca atggtaataa caacgtttct aatctgttta atattgagat
    12961 atagtgacaa gtggaggatt ttatgattat agaagctata ggtttacctg gaagcggaaa
    13021 aacgttttta ttccatgagc ttgaaaaaga atttcggagt aattcaatca gaacttataa
    13081 ttttactgaa ttatcacgga ataatatttc agtcaaaatt gttgtaaaat tattgctaaa
    13141 gtttgtatcg ttgaaatata tttgtaaaaa atggaaaaaa gaattatacg atattctttc
    13201 tgaagagctt ccgtatgaga gtaaatttga tttatatgaa aatccagatt attgtgtgaa
    13261 ttatgcgctt atgcttctct ttatctatag attatttcaa aatagtaaaa ttgtattatt
    13321 actagatgag ggaatgtatc ataatattgt gaaattatgt gctgactttg atttttcaat
    13381 cagactatca aataagttaa ttgaaaaatg tgtattgtta agtagattaa atgatagtaa
    13441 gcatatagtt atttacaata tttttccaat ttctgagaca ctattgtcta ttgaaaaacg
    13501 taatcgacat gtgtctaaat ttgatgaact agaaactacc cagttgagca agatattaga
    13561 taactacgat aaactaaata atgcaatcta taataatgac aaaaaacaga taatatcagt
    13621 ttttagaaag gattttattg aaaagaatat ttcttatata aaacaaaatt taaatattta
    13681 atgctctgct agttattatt ttggcaggta atataagcgt ttattctcta ataattgata
    13741 agtacgatga ggtataatat ggtaattttt gtggtgttgc attacatggt ttttaaagaa
    13801 actaaacaat gcgtcaattc aattaagaat aatgttaaag gagaaaagaa aattataatt
    13861 gttgataatt gttctcctaa tggctcatat agtagtttag tagatgcttt tggttgtgat
    13921 aaagatatta ttattatgaa gtcagatagt aatttaggct ttgctagggg aaataatctt
    13981 ggttataaat atgcagttga aaattttaat ccagatttta ttgttgtaat gaacaatgat
    14041 atggaaatat ttcaagaaga ttttattgat aaactgtatg aaagttacgc aaagtatggc
    14101 tactatatat taggtccaga tatatattca actaaacagg aatatcatca aaatcctcag
    14161 acaagaaagg ttctggatag gtctgatttg aagttattat atcgaaagct agttattaaa
    14221 gataggctaa ggttcttagt tcctgtaaaa tggtggttta aaaatatatt aattaaaaat
    14281 aaaagtgtag ataataattc aaaagataaa aatgaatatg ttcaaaatat agtaaaaaat
    14341 ccgttattac atggctcgtg ttatgttttt tctaagaagt ttactgaaaa acatcaacac
    14401 acatgttttt atgataaaac gtttatgtat atggaggcag aaattttaca ttatatggca
    14461 ttgaagaaca atgaattaat gctttattac ccagatttaa aagtttacca tcatgaagat
    14521 gtggcaacag attcaacgtt tgtaaagcaa tataagaaat cgttcttctc aatcaggtgt
    14581 ctactgcagt caacaaaagc gtttattgat ttaattgatt cagataaaaa agagtaacaa
    14641 atggaaagtc aaaaaaagag cgttgaaaag aattatattt ataatttgat ttatcaaatg
    14701 ctaactgtag ttattccaat tatcataaca ccctatattt cacgtgttct aaacgctgat
    14761 gggataggga tttttagcta cacaacagca gtggtaggtt attttgtttt attgggtaat
    14821 ttaggaattg caacttacgg acaactacaa gttgctaaat accaagaaga cagatttaaa
    14881 ttatccaaaa tattttttga gttattgatt ttacgaacta tattgctttt actagtttta
    14941 ctgatatatc ttgtatttat ccaatttcaa gatataattt ataaatctat ttattacgtt
    15001 ttaataattc aaatactttg tagtttgctg gatatttcat ggtttttgca gggtcttgaa
    15061 gaatttaaaa gtattgtgat gcgtaatacc ctaataaagg tgttaagtgt aatatctatc
    15121 ttgatttttg taaaaaaaga tacagatttg attttatatg ctttgattat gaacgcatca
    15181 acactgcttg gaaatatttc tatttttgca tatgtaccta aatatgttca aagagttaag
    15241 ttggctgaga ttaatttatt aaagcatatt tcacactgtt tagtttactt tataccaaca
    15301 atagcaacta caatatattt aactttggat aagacaatga taggttggtt ttccttaaat
    15361 acttttgaaa atggttatta tgagcaggct caaaaaattg agcagatggt tgtgacaata
    15421 gttacatctt taagtgtagt aacgatgcct agaatgactt atttattgaa taacaatcaa
    15481 tttcaagaat ttaaagtgcg acttgaacaa tcgataaggt ttatcctttt tttatcctta
    15541 cctatgagtt taggattagt agggatagca aataatttta tacctttgtt tttaggtgta
    15601 ggatttgaaa agtctatatc aatattaaag atttttagtc tactagttat cattataggt
    15661 ttaaataatg cattagggaa gcaaatactt atgccttcag ggcagcaaag ggcttataat
    15721 attagtgtgg taataggtgc tgttatcaat atagtcttca atttaatatt gataccgcaa
    15781 tttttttcac tgggtgctgc gatttcttcc gttcttgcag agtttgcaat tttaataata
    15841 tttctctatt attctagaaa ttgtattcct cctaaatggg ttattagaac agcagtgaaa
    15901 taccttggat ctagtatagt aatgtttctt attattagga caatagagct actatctcct
    15961 ccttcgtgga cagttgttat aatacaagtc attgttggag tcgcagtata tattctatcg
    16021 ttatatatat taaaagatca aattgtaaga aaatactatc taagattgag aaaactaaat
    16081 gttcttgcaa ggaaagtatg agagtcttat aataattatt cagaatatgg agagatttca
    16141 gtgagtattt tttcaacatt gattaaaaaa aagggcgcag agatttttaa agacttaatt
    16201 cagtcaagag tgctttttag aacgatagct attttacctc tggttggttt ttcaaaaaaa
    16261 tcattagaga tagtccgtct aaataatagt aatgtagttc tttcaaaatt gagaaggaag
    16321 tataagcaga ctattaaaaa cttggataga gagaaacagt attcacttag ctataatcag
    16381 cgacataaag atgcatcaaa taagatatgg atttgctggt ttcaaggctt agatactgcc
    16441 cctcatgtgg ttcaggagtg tatcgcttcg gtaaaaaaac acctagcaga cagagaagtg
    16501 gttgttttaa cagatgaaaa ttaccatcag tatgtgactt ttccagacta tatcaaagaa
    16561 aaagcaaccc agggttttat ttcaaaagcg cactttgcag atttattgcg cttggaatta
    16621 ctgaccgagt atggtggtac gtggattgat gggacgatat tttgttcgag ttcagatatt
    16681 cctgcctata tgttagattc tgatttattt ctatttcaaa atttaaaacc aggtcttgat
    16741 ggacaggcat tggcaatttc taattggttc attactgcta gctactctaa ccatcctctt
    16801 ttaaatatga cgaaagattt gctttatgat tattggaaga atcataatgg agtggttgat
    16861 tattttattt ttcatcactt ctttcagtta tcaatcgaag aatttcctga atactggagt
    16921 aaggtagttc ctttcaataa ttcaactcct catattttgc agttacgctt atttgaagag
    16981 tttgacgaag tgatgtatgg ttatattctc gaacagacac cattccataa gctaacatat
    17041 aaatttgaag aagaaaagtc gagaataccg aatacttact ataaacactt attttgataa
    17101 aaatgatagt agttgattga gagactgttg ttaggtatag aatgctattg agattttatc
    17161 gggagggatg atatgaaaga actaactact cgagagatgc aagaagtatc gttggagatt
    17221 ttacacacga ttgctagtat ttgtgaaaaa caccattttc gctatgcttt gatttacggg
    17281 actttaattg gtgcggttag gcataaaggg tatattcctt gggatgatga tgttgacatt
    17341 atgatgcctc gaccagatta tgaccgccta ttggagtatt tgaaggaaaa tatcgccgat
    17401 tatccacatt taaaagtatt caatcgagaa gagtgtccag aatatcctta tatgattact
    17461 cgaattagtg atcagagata ccggattgag atggaaaatg agaaaccttt tgatttgggg
    17521 gttttcattg atatctatcc ctatgatggt ttgggagata cgaaagaaga ggcggttgac
    17581 tttggtatga agggggatcg tttatcgtcg ttttgttatc aggcaactag agaacatttt
    17641 gcgattgaaa cgacaacatc aacttttagg aagttgatta agtatccagt ttatttattc
    17701 tctaaaatga ttgggaaaga ttacttccaa aagcaactag ccaagttagc cagagttaaa
    17761 gactacgata acagtgaata tgtaggttgc gttatttggt tgtcatgggg agaaaaagat
    17821 atttttccgc gtgaatggtt tgatgagact attttggttc cttttgagaa atatgaattt
    17881 aggattccta aagaatttga taaagttcta cggcatgaat atggagatta catgattttg
    17941 cctccagaga aggatagagt agggcatcac tattttaaag cttataaaaa atgataattt
    18001 gctaagcaaa gaaaaggaaa atcatgaaat tattttattt tatttacaat tggagtagaa
    18061 agtttaaggg tggagttttt ctgctcagag ttctatatgg ttttgagtgc ccacgtaaag
    18121 ctaaaattgg gaaaaacgtc aatttttcac atcgtgggat gggaacagtt gtaagtagta
    18181 atgctatcat tggggataat gtgactatac aacatcatgt aacattagga attaaaaacg
    18241 ataatgatag aattatcatc ggggagaact gttttatagg agcctatgca tttatcttag
    18301 gaaatgtaaa aattggtgca aattctaaga ttggagcagg tacgatggtt ttacatgatg
    18361 tcccagatgg aagcacagta gttaatcctg tggaactaaa agcacttgct tcaaaaaaag
    18421 acgttcagta agagagaaat gaatagaata ttgaaaacaa tgttatagga aagtcatggt
    18481 aacactttat aatactgaaa attttattca ctttttaaca cattagagtt aatgtttact
    18541 ccacaaattt aatttaatca ctcaataaag agattaagag acaagcaaaa aaaagattgt
    18601 ctttccgaat ggagaagcct tagattattg tctggttccg atgaatacaa agtaaaatat
    18661 aaaaattgca ataacaaaga attcgaattt tgttcaggtg ctttataaag cctatttgag
    18721 taattaaata gcaacttgac actgtgatta cataaaatta ttgataagcc taatttttat
    18781 ttaatcgtat ggattattta taaaaaatgt ataaaattga atataaatgt gaggtgtgat
    18841 tttggtttat aaacatggga aaataaaagt gcaaataaca aagaaaggta ccctactatg
    18901 aaaggtatta ttttagcagg tggttcgggg acacgtttat atcctttgac tcgcgctgca
    18961 tcaaaacaac ttatgccggt ttatgataag ccgatgattt actacccact ttcaacattg
    19021 atgttggctg ggattaggga tattttgatt atttccactc cacaggattt acatcgattc
    19081 caagagcttc ttcaagacgg atctgagttt gggatcaaac tttcttatgc agagcaacca
    19141 agtccagatg gtttggcaca agcctttatc attggggaag agtttatttc tgatgatagc
    19201 gttgcgctaa tcttaggtga taatatctac catggttctg ggctttccaa gatgctacaa
    19261 aaggcagcga gtaaggagtc gggagcaact gtttttggct accatgtcaa ggatccagag
    19321 cgctttggtg tggttgagtt tgatcaggat atgaaggcta tttctattga agaaaagcca
    19381 gagtaccctc gttcaaacta tgcagttaca ggtctctatt tctatgataa tgatgtagta
    19441 gagattgcca agagtattaa cccaagtcct cgtggtgaac tggaaattac agatgtaaac
    19501 aaggcttacc tagatcgtgg tggtttgtct gttgagctta tgggacgtgg ctttgcttgg
    19561 ctggatactg gaactcatga aagtttacta gaggcctcac agtacatcga aacagtgcaa
    19621 cggatgcaaa atgttcaggt agcaaactta gaagaaattg cttaccgtat gggctatatc
    19681 agtaaagagc aagtgcatga attggcgcag ccgttgaaga aaaatgaata cgggcagtac
    19741 ctgctccgtt tgattggaga agtatagatg acagataatt ttttcggtaa gacgcttgcg
    19801 gcacgcaagg ttgaagctat tccaggcatg ttagagtttg atatccccgt tcatggagat
    19861 aatcgtggct ggtttaaaga aaatttccaa aaggaaaaaa tgcttccact tggatttcca
    19921 gagtctttct ttgcagaagg aaaattgcaa aacaatgtat ccttctcacg taaaaatgtc
    19981 cttcgaggcc tccacgcaga gccttgggat aagtacatct ctgtagcaga tggagggaaa
    20041 gttctgggtt cttgggttga tctacgcgag ggtgaaacct ttgggaagac ctatcagaca
    20101 gtaattgatg caagcaaggg aatctttgtt cctcgaggcg tagctaatgg cttccaagtt
    20161 ttatcagata cagcttcata tagctatctg gtcaatgatt actgggctct tgaactcaaa
    20221 cccaagtatg cctttgtgaa ctacgctgat ccaagccttg gtattgaatg ggaaaatctg
    20281 gaagaagcag acgtatctga agcagacaaa catcatcccc tacttaagga cgtgaagcct
    20341 ttgaaaaaag aagatttgga ataaggaaag aatatgactg aatacaaaaa tattatcgtg
    20401 acaggtggag ctggctttat cggttctaac tttgtccatt atgtttacga gaactttcca
    20461 gatgttcatg tgacagtcct agataagttg acttatgctg gaaaccgcgc gaatattgag
    20521 gaaattttag gcaatcgtgt tgagttagtt gttggtgaca ttgctgatgc ggagttggta
    20581 gacaagttgg ctgctcaagc agatgctatc gttcattatg cagcggaaag ccacaatgat
    20641 aattcgctca atgatccatc gccatttatt catactaact tcattggaac ctatactctt
    20701 ttagaagctg ctcgtaagta cgatattcgc ttccaccatg tatcgacaga tgaagtttat
    20761 ggggatctcc ctttacgaga agatttgcca ggtcatggtg aaggcccagg tgagaaattt
    20821 actgctgaaa caaaatacaa ccctagctct ccgtactcat caaccaaggc agcctcagat
    20881 ttgattgtca aagcttgggt gcgttctttt ggagtcaagg caacgatttc caactgttca
    20941 aataactacg gtccttatca acatatcgaa aaattcatcc cacgtcagat tactaacatc
    21001 ctaagtggaa ttaagccaaa actttacggt gaaggtaaga acgttcgtga ctggattcat
    21061 accaatgacc attcttcagg agtttggaca atcttgacaa aagggcaaat cggtgaaacc
    21121 tacttgattg gggctgatgg tgagaagaac aataaggaag ttttggaact tatccttaag
    21181 gaaatgggac aagctgcgga tgcctatgat catgtgactg accgtgcagg acatgacctt
    21241 cgctatgcga ttgatgccag caagctccgt gatgagttgg ggtggaaacc tgaatttact
    21301 aactttgaag ctgggctcaa ggcaacaatc aagtggtata cagataacca agaatggtgg
    21361 aaagcagaaa aagaagctgt tgaagccaat tatgctaaga ctcaggagat tattacagta
    21421 taaaaagcag gaaatagctg ctttttattg ctatattggg aagagttaca tattagaaag
    21481 gtctagagat gattttaatt acaggggcaa atggccaatt aggaacggaa cttcgctatt
    21541 tattggatga acgtaatgaa gaatacgtgg cagtagatgt ggctgagatg gacattacca
    21601 atgaagaaat ggttgagaaa gtttttgaag aggtgaaacc gactttagtc taccattgtg
    21661 cagcctacac cgctgttgat gcagcagagg atgaaggaaa agagttggac ttcgccatca
    21721 atgtgacggg gacaaaaaat gtcgcaaaag catctgaaaa gcatggtgca actctagttt
    21781 atatttctac ggactatgtc tttgacggta agaaaccagt tggacaagag tgggaagttg
    21841 atgaccgacc agatccacag acagaatatg gacgcactaa gcgtatgggg gaagagttag
    21901 ttgagaagca tgtgtctaat ttctatatta tccgtactgc ctgggtattt ggaaattatg
    21961 gcaaaaactt cgtttttacc atgcaaaatc ttgcgaaaac tcataagact ttaacagttg
    22021 taaatgacca gtacggtcgt ccgacttgga ctcgtacctt ggctgagttc atgacctacc
    22081 tagctgaaaa tcgtaaggaa tttggttatt atcatttgtc aaatgatgcg acagaagaca
    22141 caacatggta tgattttgca gttgaaattt tgaaagatac agatgtcgaa gtcaagccag
    22201 tagattccag tcaatttcca gccaaagcta aacgtccgct aaactcaacg atgagcctgg
    22261 ccaaagccaa agctactgga tttgttattc caacttggca agatgcattg caagaatttt
    22321 acaaacaaga agtgagataa gtagtagaat gattttctag tctaataaaa gaggtagata
    22381 atgaactcca aaggagctta agatatacga ttatcttgtt gttggtgctg gtctctttgg
    22441 tgcatagcta tggctcagtt tctattatcg ctcacaccat ccatcagaag tttaatctga
    22501 aggtacccaa ttatcgccaa gaagaagatt gggctaagat gggtttacca atcacacgca
    22561 aggaaatctc taattggcat atcaagacga gtcaatacta tttggagccc ctctataacc
    22621 tcttgcgaga gagactattg actcagccct tacttcatgc ggatgaaact tcttataggg
    22681 tgctagagag tgatagtcag ctgacttact attggacttt tttgtcaggt aaatcagaga
    22741 aacaagggat tacgctttac caccatgatc agtgtcgaag tggttcagta gtacaagaat
    22801 tcctaggaga ttattctggc tatgtgcatt gtgatatgtt gcggcagtaa cttaggactt
    22861 tagtcctcta gttctgccta tgcgatagca gtccaaggtt taggagcaag gcgacgctaa
    22921 gcttggtaaa ctgcgaaccg ctagaagctt atcgtcaact ggaagaagct gaacttgttg
    22981 gatgttgggt acatgtgaga aggaagtttt ttgaagcgac ccccaagcaa gcggataaat
    23041 catccttagg agctaaaggt ttagcttatt gtaatcagtt attttccttg gaaagagact
    23101 gggaggcttt gccagctgat gaacgactac agaaacgtca agaagagctc caacccctac
    23161 tggaagactt ctttgcttgg tgccggcgtc agtcagtttt atcgggttca aaactaggaa
    23221 gggcaattga atacagcctc aagtataaag aaacctttaa gaccattttg aaagacggac
    23281 atctggtcct ttccaataat ctagctgaat gcgccattaa atcattggtt atgggacgga
    23341 gtaaaagagt ccagtggact cttttagcct aagctcagtt taaaaaagcg agggtggtta
    23401 ttttctcaaa gttttgaagg agctaaagca agagctatta ttatgagttt gttggaaaca
    23461 gctaaacgtc atcaattaaa tagcgagaaa tatctattct atcttctaga atgtcttcca
    23521 aacgaggaaa ctctcgtaaa caaagaggtt ttagaggttt atttatcatg gactaaagtt
    23581 gtacaagaaa agtgcaaata agaaatctcc agattaggaa ctatccgtga gttctctagt
    23641 ctggagattt ttcaatatac ttcggctctt tgtcaactgt agtgggttga agaaaagcta
    23701 agcttgagaa aggacaaatt tcgtcctttc ttttttgata ttcagggcga taaaaatccg
    23761 ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg cgcttgataa gtttgatgag
    23821 attattggtc gcttccagtt tggcattaga atagtgtagt tgaagggcgt tgacgatttt
    23881 ctctttgttc tttagaaagg ttttaaagac agtctgaaaa agaggatgaa cctgcttcag
    23941 attgtcctca atgagtccga aaaatttctc agggtctttg ttctgaaagt gaaaaagtaa
    24001 gagttgatag atctgatagt ggtgtttcaa gtcttctgaa tagcttaaaa tcttgtcaag
    24061 aatttcttta tttgttaagt gcatgcgaaa agtagggcga taaaaacgtt tatcgctcaa
    24121 tttacgacta tcctgttgga tgagtttcca gtaacgcttg atagccttgt attcatgaga
    24181 ttttcgttca aactgattca taatttgaac acgaaaacga ctcatggcac ggctgagatg
    24241 ttggataata tggaaacgat ctagaacgat tttagcacac ggaaaaagct gtttagccaa
    24301 gtcatagtaa ggactaaaca tatccatcgt aatgattttc acttgacaac gaacggctct
    24361 atcgtagcga agaaagtgat ttcggatgac agcttgtgtt ctgccttcaa gaacagtgat
    24421 aatattaaga ttatcaaaat cttgcgcaat gaaactcatc tttcccttag tgaaggcata
    24481 ctcatcccaa gacataatct ttggaagccg agaaaaatca tgctcaaagt gaaagtcatt
    24541 gagcttgcga atgacagttg aagttgaaat ggccagctga tgggcaatat cagtcataga
    24601 aattttttca attaactttt gagcaatttt ttggttgatg atacgaggga tttggtgatt
    24661 tttctttacc aggggagtct cagcaaccat catttttgaa cagtgatagc acttgaaacg
    24721 gcgttttcta aggagaattc tagaaggcat accagttgtt tcgaggtaag ggatcttaga
    24781 cggtttttga aagtcatatt tcttcattag acttccacaa tcagggcaag atggagcctc
    24841 ataatccagc ttagcgataa tttctttgtg ggtatccata ttgatgatat ctagaatctt
    24901 gatgtttggg tctttaatat cgagcagttt tgtgataaga tgtaattgtt ccatatgatt
    24961 ctttctaatg agttgttttg tcgcttttca ttataggtca tatgggactt tttttctaca
    25021 caaaaataag ctccataata tccatagggg atttacccac tacaaatatt atagagccta
    25081 tacttcgtta ttgggcggtt acgatattca tattttttgc aaagatattg tttgaaaaat
    25141 aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga
    25201 gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta tttgcccttg cgggcgtgac
    25261 attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga
    25321 gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt tg
//
