LOCUS       CR931706               19741 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 7765/43 (serotype 35c).
ACCESSION   CR931706
VERSION     CR931706.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19741)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 19741)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..19741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="7765/43"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC35C_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC35C_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34319.1"
                     /db_xref="GOA:Q4JZD8"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4JZD8"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAP
                     WDAFCVELL"
     gene            323..491
                     /gene="aliB"
                     /locus_tag="SPC35C_0002"
                     /pseudo
     CDS             323..491
                     /gene="aliB"
                     /locus_tag="SPC35C_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(492..1024,1026..1352))
                     /gene="tnp"
                     /locus_tag="SPC35C_0003"
                     /pseudo
     CDS             complement(join(492..1024,1026..1352))
                     /gene="tnp"
                     /locus_tag="SPC35C_0003"
                     /note="member of homology group 4; member of homology
                     group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(962..1024,1026..1334))
                     /gene="tnp"
                     /locus_tag="SPC35C_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 3.8e-23"
                     /pseudo
     gene            1559..3013
                     /gene="wzg"
                     /locus_tag="SPC35C_0004"
     CDS             1559..3013
                     /gene="wzg"
                     /locus_tag="SPC35C_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34322.1"
                     /db_xref="GOA:Q4JYW1"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JYW1"
                     /translation="MLIMSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNI
                     LAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGL
                     TNRLNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNT
                     DLTVNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKV
                     EAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPI
                     ADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVY
                     NDQEFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKL
                     TSTEALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDL
                     PSYAMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1559..1684
                     /gene="wzg"
                     /locus_tag="SPC35C_0004"
                     /note="Signal peptide predicted for SPC1688 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 42 and 43"
     misc_feature    1772..2119
                     /gene="wzg"
                     /locus_tag="SPC35C_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 8.6e-63"
     misc_feature    2297..2740
                     /gene="wzg"
                     /locus_tag="SPC35C_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 2.5e-69"
     gene            3015..3746
                     /gene="wzh"
                     /locus_tag="SPC35C_0005"
     CDS             3015..3746
                     /gene="wzh"
                     /locus_tag="SPC35C_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34323.1"
                     /db_xref="GOA:O86886"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:O86886"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDRGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHIIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    3018..3626
                     /gene="wzh"
                     /locus_tag="SPC35C_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 4.6e-36"
     gene            3752..4447
                     /gene="wzd"
                     /locus_tag="SPC35C_0006"
     CDS             3752..4447
                     /gene="wzd"
                     /locus_tag="SPC35C_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34324.1"
                     /db_xref="GOA:O86887"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:O86887"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKL
                     DMPAKTLASKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKI
                     PLLGLVPDFDKIK"
     misc_feature    3752..3868
                     /gene="wzd"
                     /locus_tag="SPC35C_0006"
                     /note="Signal peptide predicted for SPC1690 by SignalP 2.0
                     HMM (Signal peptide probability 0.625) with cleavage site
                     probability 0.411 between residues 39 and 40"
     misc_feature    3773..4189
                     /gene="wzd"
                     /locus_tag="SPC35C_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 3.1e-55"
     misc_feature    4295..4372
                     /gene="wzd"
                     /locus_tag="SPC35C_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4457..5146
                     /gene="wze"
                     /locus_tag="SPC35C_0007"
     CDS             4457..5146
                     /gene="wze"
                     /locus_tag="SPC35C_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34325.1"
                     /db_xref="GOA:Q4JZK1"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZK1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSANIAWAFARAGYKTLLIDGDIRNSVMLGVFKARNKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRNCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            5161..6528
                     /gene="wchA"
                     /locus_tag="SPC35C_0008"
     CDS             5161..6528
                     /gene="wchA"
                     /locus_tag="SPC35C_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34326.1"
                     /db_xref="GOA:Q4JYV7"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4JYV7"
                     /translation="MNGKILRSSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYLNFKGSKKILLLTATSRVEKVLDRLIESNEVVGKL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHIMAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     misc_feature    5161..5247
                     /gene="wchA"
                     /locus_tag="SPC35C_0008"
                     /note="Signal peptide predicted for SPC1692 by SignalP 2.0
                     HMM (Signal peptide probability 0.844) with cleavage site
                     probability 0.429 between residues 29 and 30"
     misc_feature    5944..6525
                     /gene="wchA"
                     /locus_tag="SPC35C_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 4.8e-158"
     gene            6515..7321
                     /gene="wciB"
                     /locus_tag="SPC35C_0009"
     CDS             6515..7321
                     /gene="wciB"
                     /locus_tag="SPC35C_0009"
                     /note="member of homology group 16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34327.1"
                     /db_xref="GOA:Q4JZB6"
                     /db_xref="UniProtKB/TrEMBL:Q4JZB6"
                     /translation="MERSRLIDVKIIVATHKEVKMPQDNSLYLPIHVGRDGKSDIGFI
                     GDNTGDNISSLNPYYCELTGLYWAWKNLDYNYLGLVHYRRYFTNKSQGYNENVNMDDV
                     ILSRSNVEILLEKSDVIVPKKRKYYIETLYSHYAHTLNGEHLDLARKIIEQNSSEYLS
                     SFDKVMKQRSGYMFNMFIMKKGLLDDYLPWLFSILDTMYEQMDLTDYTSFESRLFGRV
                     SELLFNVWLCKKGITPKEVPFMYMERVDLFEKGKSFLMAKFFGKKYGQSF"
     gene            7330..8523
                     /gene="wzy"
                     /locus_tag="SPC35C_0010"
     CDS             7330..8523
                     /gene="wzy"
                     /locus_tag="SPC35C_0010"
                     /note="member of homology group 45"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34328.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JYV5"
                     /translation="MKITIKRYSLPEILGLAALAIFLLFSLLSITLYAQYISIKVYFI
                     ALFGIILLIFLKELISESYNLKSVIGLFVIFTLCFIIGTVTNYAYFFILGLFLIYSLR
                     NLPFSDVAKVSFIISISVLLLVVLSSKLGIIPDYIEISPTRVRHYLGFRYSLLPSTLM
                     MNIIAISFFLKQENASYPRLLVLFLLSGWLYVETDSRLTFINSCLFLLVNLIMKLSPS
                     IIEKVGRLLKLFSFTYFINACLSYWIAKTYLNTSNVVLNQFFYQADQFLGGRIYYSNR
                     SLSLYGYKLLGQKIDWIGNGLSIQGERSTETYLYVDNLYIQILQHFGLIVSVIILSLL
                     TITLVKLLKKGQMVLGIILVILSFHALIDDLILNLYYNIFWVLIGMLIYKKYQFYDKK
                     QLTIE"
     misc_feature    7330..7431
                     /gene="wzy"
                     /locus_tag="SPC35C_0010"
                     /note="Signal peptide predicted for SPC1694 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.778 between residues 34 and 35"
     gene            8678..9673
                     /gene="wcrI"
                     /locus_tag="SPC35C_0011"
     CDS             8678..9673
                     /gene="wcrI"
                     /locus_tag="SPC35C_0011"
                     /note="member of homology group 128"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34329.1"
                     /db_xref="GOA:Q4JZB4"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JZB4"
                     /translation="MNKINLTDNLPLISVVLPVYNVENYLEKCLNSVVRQTYKNIEII
                     IVNDGSLDSSIDICNKYANKDSRIKVFTKPNGGLSDARNFGVKKSMGEFITFVDSDDY
                     VTDDYVEYLYSLVKKYNCKMSMCSIFVHYISNDKMINNGTGRELMMTAEQCIEKMCYH
                     DEVDTCAYAKLYHRSLFSEICFPKGRIFEDIGTIYRFFGTAGQIACGFNAKYYYEIRE
                     NSIVTSSFSEKKFDLLFMTDQMRNFVDQRYPSLKAATKRRAVYARFSTLNQLLDVQGY
                     NEEKKEIIRFIQDNKEALLENPKTPKRDRLAVRALSLGFCIYKLLWKQYLKIQRG"
     misc_feature    8717..9220
                     /gene="wcrI"
                     /locus_tag="SPC35C_0011"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1.2e-47"
     gene            9675..10826
                     /gene="wcrJ"
                     /locus_tag="SPC35C_0012"
     CDS             9675..10826
                     /gene="wcrJ"
                     /locus_tag="SPC35C_0012"
                     /note="member of homology group 129"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol phosphotransferase"
                     /protein_id="CAI34330.1"
                     /db_xref="GOA:Q4JYV3"
                     /db_xref="InterPro:IPR007554"
                     /db_xref="UniProtKB/TrEMBL:Q4JYV3"
                     /translation="MNKEFLKYIYIRLLRNLRRIFFIIPIIRNRVVFESFSGDAYSCN
                     PKYISEELRKQYGDSVEIIWAFNDPNKFKKELPKEIVTCRYRSFNHLIYRITSKVYVC
                     NFLQAIEIPKRKGQLEIQTWHGGGCYKKVGVAEKGRQAAYVKRQRMHVEETDLFITSS
                     KYFENEVVKKQFGYKGEILSIGMPRNDILINLPISSQVEKLKEKLGLPNNKLIALYAP
                     TWRSGTKQYETLDIKKLTQAVDKKFGKKCIVLFRSHLYGNQSYDDVVDVSQYSDMQEL
                     LLLSDILITDYSSSMWDFSLSFKPCFLYTPDLKDYLDERGFDEDIHSWGFSVSESNKE
                     LVENILQFDNEEYRQKMKNHHQFLESYEQGDAAKRVVAKIAEYCNLYRG"
     misc_feature    10275..10802
                     /gene="wcrJ"
                     /locus_tag="SPC35C_0012"
                     /note="HMMPfam hit to PF04464,
                     CDP-Glycerol:Poly(glycerophosphate) gl, score 5.1e-37"
     gene            10830..11735
                     /gene="wcrK"
                     /locus_tag="SPC35C_0013"
     CDS             10830..11735
                     /gene="wcrK"
                     /locus_tag="SPC35C_0013"
                     /note="member of homology group 130"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34331.1"
                     /db_xref="GOA:Q4JYV2"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4JYV2"
                     /translation="MKKIAYLIKRYGVKNVVLRAINDVLPVNLIFPSQQLRRLNWQEK
                     VKKKLKKYVVISDSIKSEEECDIIWWLWFQGLDNAPAIVKKCRESVDKYAKRSGKRVI
                     ELTSQNLFEYIEVPNELYVKYKSGSLPLALFSDFCRISLLSNYGGLWIDSTVLITGEI
                     EDEILNQDIFMFQASPLDYSVTKISNWMLYSKYPGHPFISSIRDTLISFYNKNNTIPD
                     YFLFHLLVSCLIDDNRINQSFYDMDYYTNTYPHLLGRVLSEPYDTLKFENILRKTSIH
                     KLSYKNLDNVAEDSFYNAILGLDFS"
     misc_feature    10884..11714
                     /gene="wcrK"
                     /locus_tag="SPC35C_0013"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 4.7e-51"
     gene            11753..12469
                     /gene="mnp1"
                     /locus_tag="SPC35C_0014"
     CDS             11753..12469
                     /gene="mnp1"
                     /locus_tag="SPC35C_0014"
                     /note="member of homology group 131"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IspD-family transferase (mannitol)"
                     /protein_id="CAI34332.1"
                     /db_xref="GOA:Q4JYV1"
                     /db_xref="InterPro:IPR001228"
                     /db_xref="InterPro:IPR018294"
                     /db_xref="UniProtKB/TrEMBL:Q4JYV1"
                     /translation="MNLAVIFAGGSGTRMNAKDRPKQFLLVHGKPIIVHTIELFENHP
                     EIDGIIVVCIEDWIPYMEEMKYCYRLDKIAKIVPGGATGQLSIYNGLVAAEQLYGIED
                     NVVLIHDGVRPLITADTISDNIQSVKEKGNAITCTVAKETVILVDDENKVDEVPSREH
                     SRFAKAPQSFWLKDILGAHRASVDNGRNNFIDSCTMMRYYGHDLHVVVGPYENIKITT
                     PDDFYTFRALYDLRENKQLK"
     misc_feature    11759..12448
                     /gene="mnp1"
                     /locus_tag="SPC35C_0014"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 6.5e-05"
     misc_feature    11759..12451
                     /gene="mnp1"
                     /locus_tag="SPC35C_0014"
                     /note="HMMPfam hit to PF01128, Uncharacterized protein
                     family UPF000, score 3.9e-23"
     gene            12480..13550
                     /gene="wcrH"
                     /locus_tag="SPC35C_0015"
     CDS             12480..13550
                     /gene="wcrH"
                     /locus_tag="SPC35C_0015"
                     /note="member of homology group 51"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34333.1"
                     /db_xref="GOA:Q4JYV0"
                     /db_xref="InterPro:IPR016503"
                     /db_xref="UniProtKB/TrEMBL:Q4JYV0"
                     /translation="MKYFVEETLLDEQDKKNAGGKARQDVTDILESIGYQKLIAESEM
                     NERQELNAVQRLVHHYKVKKMWKKTLSVVGKGDEVIIQFPLLNHSLFFNQVIKQLSKN
                     GVKVYFLIHDLESLRWSQSKSISLKSRIRLNIEEHSVLRLSEGIIAHNKKMKSYIKTY
                     SVESSKIIPLETFDYIIPSYHERKNLDNFQLNAPIVIAGNLKQHKAGYVYHLPSNVEF
                     NLYGIGYEQTDDKSVHYCGSFMPEELPFVLKGSFGLVWDGPSSESCIETYGEYLRVNN
                     PHKTSLYLASGIPVVVWSEAAIASFIKENNCGILVSNLSELPELLSMITVDEYELMKK
                     NTEIIGERLRQGFYTKQAVKGF"
     gene            13566..14645
                     /gene="mnp2"
                     /locus_tag="SPC35C_0016"
     CDS             13566..14645
                     /gene="mnp2"
                     /locus_tag="SPC35C_0016"
                     /note="member of homology group 132"
                     /codon_start=1
                     /transl_table=11
                     /product="putative dehydratase/epimerase (mannitol)"
                     /protein_id="CAI34334.1"
                     /db_xref="GOA:Q4JZA9"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JZA9"
                     /translation="MIESFNDKVLQEDLEIIAKEELPFRKFRNSTVFITGVTGLVGLQ
                     LFKALACINRVHQLNMKIIGLVRNLDKAEKIFGDLLKRKDIQIVLGDVSEDFHSYIPD
                     GLVIDYIIHGASVTTSKLMIEFPVDTIRVAFNGTYQMLELAKEKKVKSFVYLSSMEVY
                     GSFQSDRTTVVNENMLGYLDLTSVRTNYPECKRICENMCIAFLSQYQVPAKIARLSQT
                     FGAGTLPGENRVFAQFARSVMQGKDIVLHTLGQSEGNYCYTADTVVALLTILLRGENG
                     EAYNIANEESHTTIADMAKMVTSQFSQTSQVVFDIPKKNIFGYAVDTKMKLSTHKIQQ
                     LGWKPRVSLVDAYDRMMRSMNETGV"
     misc_feature    13659..14411
                     /gene="mnp2"
                     /locus_tag="SPC35C_0016"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 9.2e-23"
     misc_feature    13662..14504
                     /gene="mnp2"
                     /locus_tag="SPC35C_0016"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/iso, score 0.00013"
     gene            14654..16069
                     /gene="wzx"
                     /locus_tag="SPC35C_0017"
     CDS             14654..16069
                     /gene="wzx"
                     /locus_tag="SPC35C_0017"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34335.1"
                     /db_xref="GOA:Q4JZA8"
                     /db_xref="InterPro:IPR002528"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JZA8"
                     /translation="MKVLKNYLYNLSYQLLVIILPIITTPYVTRIFSSDDLGTYGYFN
                     SIVTYFILLATLGIANYGTKEISGNRKSIQKNFWGIYTLQFGATTFSIFLYILACLFI
                     PGMKNLVAYILGLGLVSKGLDISWLFQGLEDFRKITVRNITVKLVGVSAIFLFVKSAS
                     DLYLYVFLLTAFELLGQLSMWFPAREYIGKPHFDIEYARHHLKPVILLFLPQIAISLY
                     VTLDRTMLGALASTKDVGIYDQALKLVNILLTLVTSLGSVMLPRVAHLLATGDHKVVN
                     KMHEVSFLIYNLVIFPIMAGMLIVNDDFVQFFLGQDFQDARYAISIMIFRMFFIGWTN
                     IMGIQILIPHNQNKEFMISTTTPAIISVGLNLLFLPKLGYIGAAIVSVLTEALVWAIQ
                     LFYTRRYLKEVPIIGSMSKIILASAIMYGLLLSSKTVIHFSPTLNVLAFVALGGIIYL
                     FAILSLKVVDVKELKQIIRKN"
     misc_feature    14660..15454
                     /gene="wzx"
                     /locus_tag="SPC35C_0017"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.5e-65"
     gene            16071..17069
                     /gene="wciG"
                     /locus_tag="SPC35C_0018"
     CDS             16071..17069
                     /gene="wciG"
                     /locus_tag="SPC35C_0018"
                     /note="member of homology group 21"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI34336.1"
                     /db_xref="GOA:Q4JYU7"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4JYU7"
                     /translation="MRKNRNINLDLLKVLACVGVVLLHTTMGGFKETGSWNLLAYLYY
                     LGTYSIPLFFMINGYLLLGKREITYLYILQKVKWILITVSSWSFIVWLFKRDFTTNPI
                     KKIVGSLIQRGYFFQFWFFGALILIYLCLPILRQFLNSKRSYLYSLSLLMTIGLIFEL
                     SNILLQMPIQTYVIQTFRLWTWFFYYLLGGYIAQFTIEEIESRFKNWMKIVSILLLLI
                     SPIILFFIAKTIYHNLFAEYFYDTLFVKVSTLGIFLTILMLTLNENRRESIVSLSNQT
                     MGVFIIHTYIMKVWEKVLGFNFVGAYLLFALFTLSVSFIIVGMLMKIPYFNRIVKL"
     gene            17083..18192
                     /gene="glf"
                     /locus_tag="SPC35C_0019"
     CDS             17083..18192
                     /gene="glf"
                     /locus_tag="SPC35C_0019"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34337.1"
                     /db_xref="GOA:Q4JYU6"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYU6"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRNHIGGNIYCEN
                     VEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYVNSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKITEQTADMKDVEPKNLEEQAIKLIGPDVYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFDHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDEKNNAMFAKYQEEASKNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFGYDKK"
     misc_feature    17518..18120
                     /gene="glf"
                     /locus_tag="SPC35C_0019"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 1.2e-137"
     gene            18173..19207
                     /gene="wcjE"
                     /locus_tag="SPC35C_0020"
     CDS             18173..19207
                     /gene="wcjE"
                     /locus_tag="SPC35C_0020"
                     /note="member of homology group 18"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI34338.1"
                     /db_xref="GOA:Q4JYU5"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4JYU5"
                     /translation="MDMTKSRINWIDFGKGFSIFLVLAGHVLLGLYQSEKFPTANNIL
                     SLLIAQVYIFHIPVFFALSGYFFKPVSDLKEFWQYAKKKTIVFGLPYIFYSIIHFGLQ
                     KVAGASVRVPTTISDLLNIYKHPLGVSWYLYILWSILIIYGLLSILVKNRRMLFLISV
                     FAYCLTLFVQTDIYIIQRTLVWGICFFLGSVLSEIHFDKINLKKFLFFFVLFDFIYMF
                     AWFLFYEVGSKKDYVSYINPGLWGIAFIVCVLVAFAIFPKMEKNFPKTFLYFTKYGKD
                     SLGIYILHAPICSMIRILMLKVGINSVFLHVVVGIVLGWYLSILATYILKKIPFLNIV
                     LLPQKYIKLK"
     gene            19382..>19741
                     /gene="aliA"
                     /locus_tag="SPC35C_0021"
     CDS             19382..>19741
                     /gene="aliA"
                     /locus_tag="SPC35C_0021"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34339.1"
                     /db_xref="GOA:Q4K2T2"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K2T2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    19382..19468
                     /gene="aliA"
                     /locus_tag="SPC35C_0021"
                     /note="Signal peptide predicted for SPC1705 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    19628..19696
                     /gene="aliA"
                     /locus_tag="SPC35C_0021"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     6326 a   2920 c   3923 g   6572 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa cactgcggct aaagaagtac ttgaaaaaca
      121 ggtcttggct ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcatat aaaaacaagg gaggactgta taaaagacag aaatcctttg
      241 ttttttataa ccaaggttta taaactttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattta aggagaaaga agatgaacat aaagaagcga gtccttagtg caggcctgac
      361 ttttgcatct gctttgcttt tagctgcttg cggccaatca ggttcagata caaaaactta
      421 ctcatcaacc tttggtggaa atccaactac atttaactat ctattagact attacgctga
      481 taacatagtc aattgaaaca agaacaggac aaaagagcct cataaaaggt attgcaactt
      541 ggtaatacct tttacgaggc tttttgatat gagcccatgt tttctcaata ggattgtact
      601 caggtgagta gggaggaaga ggtaaaagtt tatgcccaaa ctcctcgcat aaaagttcta
      661 acttacccat tctatggaat cttgcattat ccataataat aaccgatggt gtggttaatg
      721 ttggtaagag aaacttctga aaccaagctt caaaaaagtc gctcgtcacc atctcttcgt
      781 aagtcattgg agcgattaac tcaccatttg ttagacctgc aaccaaagaa atcctctgat
      841 atcttcttcc agatacttta cctcttatta actgaccttt taatgagcga ccatattctc
      901 gataaaaata agtatcgaat cctgtttcat caatctaaac aggtgctagg tgctttaaac
      961 tattaaaatt cttaagaaat aaggctactt tttctggctc ttgttcatag taggtgtggt
     1021 tctttttttc gagtgtagcc catagctttg agcgcatagt ggatggtagt tggatgacag
     1081 ccaaattcag aagctatttc agtcaaataa gcgtctggat tgtcagtaag atagttttta
     1141 agtctatctc tatcaacctt tcttggtttt gttcctttta cttggtggtt tagctctcct
     1201 gttttctctt ttagctttaa ccagccataa atggtattac gtgagatttg gaaaacgtgt
     1261 gacgcttctg ttatactacc tgttcgctca caataagaga gaactttttt acgaaaatct
     1321 attgaatatg ccataagaag attataccac attgtgtact atattagatt gaaactagag
     1381 tagtacacct ctgcttctaa aacattgtta gaaatcgatt tgactgtcct tatttcattt
     1441 tattatattt ttggttcgcg ggaagtctac taagatactt aaagatgcag atagtgaaaa
     1501 taaaggtgta gacattaccg taaaaaagtg atataatcgt atgatgttca atgtataggt
     1561 gttaatcatg agtagacgtt ttaaaaaatc acgttcacag aaagtgaagc gaagtgttaa
     1621 tatagttttg ctgactattt atttattgtt agtttgtttt ttattgttct taatctttaa
     1681 gtacaatatc cttgctttta gatatcttaa tctagtggta actgcgttag tcctactagt
     1741 tgccttggta gggctactct tgattatcta taaaaaagct gaaaaattta ctatttttct
     1801 gttgctgttc tctatccttg tcagctctgt gtcgctcttt gcagtacagc agtttgttgg
     1861 actgaccaat cgtttaaatg cgacttctaa ttactcagaa tattcaatca gtgtcgctgt
     1921 tttagcagat agtgatatcg aaaatgttac gcaactgacg agtgtgacag caccgactgg
     1981 gactgataat gaaaatattc aaaaactact agctgatatc aagtcaagtc agaataccga
     2041 tttgacggtc aaccagagtt cgtcttactt ggcagcttac aagagtttga ttgcagggga
     2101 gactaaggcc attgtcctaa atagtgtctt tgaaaatatc atcgagtcag agtatccaga
     2161 ctacgcatcg aagataaaaa agatttatac caagggattc actaaaaaag tagaagctcc
     2221 taagacgtct aagaatcagt ctttcaatat ctatgttagt ggaattgaca cctatggccc
     2281 tattagttcg gtgtcgcgat cagatgtcaa tatcctgatg actgtcaatc gagataccaa
     2341 gaaaatcctc ttgaccacaa cgccacgtga tgcctatgta ccaatcgcag atggtggaaa
     2401 taatcaaaaa gataaattaa cccatgcggg catttatgga gttgattcgt ccattcacac
     2461 cttagaaaat ctctatggag tggatatcaa ttactatgtg cgattgaact tcacttcgtt
     2521 tttgaaattg attgatttgt tgggtggaat tgatgtttat aatgatcaag aatttactgc
     2581 ccatacgaat ggaaagtatt accctgcagg caatgttcat cttgattcag aacaggctct
     2641 cggttttgtt cgtgagcgct actcactagc agatggcgat cgtgaccgcg ggcgcaatca
     2701 acaaaaggtg attgtggcta tccttcaaaa attaacgtca accgaagcac tgaaaaatta
     2761 tagcacgatc attaatagct tgcaagattc tatccaaaca aatatgccac ttgagactat
     2821 gataaatttg gtcaatgctc agttagaaag tggagggaat tataaagtaa attctcaaga
     2881 tttaaaaggt acaggtcgga cggatcttcc ttcttatgca atgccagaca gtaacctcta
     2941 tgtgatggaa atagatgata gtagtttagc tgtagttaaa gcagctatac aggatgtgat
     3001 ggagggtaga tgaaatgata gacatccatt cgcatatcgt ttttgatgta gatgacggtc
     3061 ccaagtcaag agaggaaagc aaggctctct tgacagaatc ctacaggcag ggggtgagaa
     3121 ccattgtctc tacctctcac cgtcgcaagg gcatgtttga aactccggaa gagaagatag
     3181 cagaaaactt tcttcaggtt cgggaaatag ctaaggaagt ggcgagtgac ttggtcattg
     3241 cttacggggc tgaaatttac tacacaccag atgttctgga taagctggaa aaaaagcgga
     3301 ttccgaccct caatgatagt cgttatgcct tgatagagtt cagtatgaac actccttatc
     3361 gcgatattca tagcgccttg agcaagatct tgatgttggg aattactcca gtcattgccc
     3421 acattgagcg ctatgatgct cttgaaaata atgaaaaacg cgttcgagaa ctgattgata
     3481 ggggctgtta cacgcaagta aatagttcac atgtcctcaa acccaaactt tttggcgaac
     3541 gttataaatt catgaaaaaa agagctcagt attttttaga gcaggatttg gttcatatca
     3601 ttgcaagtga tatgcacaat ctagacggta gacctcctca tatggcagaa gcatatgacc
     3661 ttgttaccca aaaatacgga gaagcgaagg ctcaggaact ttttatagac aatcctcgaa
     3721 aaattgtaat ggatcaacta atttaggaga aatgatgaaa gaacaaaaca cgatagaaat
     3781 cgatgtattt caattattta aaaccttgtg gaaacgcaag ctaatgattt taatagtggc
     3841 acttgtgaca ggtgcggggg cttttgcata tagcactttt attgttaagc cagaatatac
     3901 gagtaccacg cgaatttacg tagtgaatcg caatcaagga gacaagccgg ggctgacaaa
     3961 tcaggatttg caggcaggat cttatctggt aaaagactac cgtgagatta tcctttcgca
     4021 ggatgcattg gaaaaagtag cgacaaattt gaagttggat atgccagcaa aaacgttagc
     4081 cagcaaagtt caagtgactg taccagctga cactcgtatc gtctcaatct ctgtcaagga
     4141 taaacagcca gaggaagcca gtcgtatcgc taattctcta cgagaagttg ctgcagaaaa
     4201 gatcgtcgct gtaacgcgag tatctgatgt aacgacactt gaagaagcgc gaccagctac
     4261 gactccctct tctccaaatg ttcgacgcaa ttccttgttt ggttttcttg gaggagcagt
     4321 cgtaacagta attgctgttc ttttgattga gttgctggac acccgtgtga aacgtcctga
     4381 agatgttgaa gatgtactga aaattccact tttagggctc gttccagatt ttgacaaaat
     4441 aaaataggag gaagttatgc caacattaga aatctcacag gcaaaattgg attctgtaaa
     4501 aaaggcagag gaatattata acgctttgtg cacgaaccta cagttaagtg gagatggttt
     4561 gaaagtattt tctatcactt ctgtgaaaat aggagaagga aaatcaacga cttccgccaa
     4621 tatcgcttgg gcttttgcgc gtgcaggtta caaaacgctg ctgattgatg gagatattcg
     4681 caattctgtt atgttaggtg tctttaaagc aaggaataag attacaggcc tgacagaatt
     4741 tttatcagga actacagact tatcacaagg gctttgtgat accaatatcg aaaatctctt
     4801 tgtaattcag gctggctctg tgtcaccgaa tccgacagct cttcttcaaa gtaagaattt
     4861 cactacaatg cttgaaacct tgcgtaaata ttttgactac atcattgtag atactgctcc
     4921 tgttggtgtc gtgattgatg cggctattat tacgcgaaac tgcgatgctt ctattttagt
     4981 gacggaggca ggtgaaataa atcgtcggga tattcaaaaa gcaaaagaac agttggaaca
     5041 cacaggaaag ccgtttttgg gaattgtgtt gaataaattc gatacttcag tagacaaata
     5101 cggttcttat ggaaattatg gagattacgg gaaaaataaa aaataggtcg ggggatagag
     5161 atgaatggaa aaatattaag gtcttcattg gccataatcc agagttttct tgttatttta
     5221 ttgacttatc tacttagtgc tgtgagagaa acggagattg tttcaacaac agctattgca
     5281 ctttatatcc tccattattt tgtcttttat atcagtgatt atggacagga tttctttaaa
     5341 aggagatatt tgattgaact tgtccagaca ttgaaatata tcctattctt tgcactagcg
     5401 attagtattt ctaatttttt cttagaggat cgatttagta tttccagacg aggcatgatt
     5461 tacttcctca cattacatgc tctcttagtc tatgtgctaa acctatttat caagtggtat
     5521 tggaagcggg cttatctcaa ctttaaagga agtaagaaga ttctcctact tacagcaact
     5581 tctcgtgtcg aaaaggtact ggatagatta atagaatcaa atgaggttgt tgggaagttg
     5641 gtagccgtca gtgtcttaga taaaccagat tttcagcatg attgtttaaa ggtagtagca
     5701 gagggggaga tagtaaactt tgcgactcat gaggtggtcg atgaagtctt tatcaatctt
     5761 ccaagtgaaa aatacaatat tggagagctt gtttctcagt ttgaaacgat gggaattgat
     5821 gtaacagtta atctaaatgc ttttgatcgt agtttggcac gtaacaagca aattcgtgag
     5881 atggcaggat taaacgttgt gactttttct acaacatttt ataagactag tcatataatg
     5941 gctaagcgga ttattgatat catgggtgca ttggtagggc tgatactatg tggtttagtc
     6001 agtattgtac tggttccttt gattcgaaag gatgggggct ctgctatttt tgctcagacg
     6061 cgtataggaa aaaatggtcg tcagttcact ttttataagt ttcgctctat gtgtgtagat
     6121 gccgaggcga aaaaaagaga actcatggaa caaaatacca tgcagggtgg aatgtttaag
     6181 gtggacgatg atcctcgtat cacgaaaatt ggtcgtttta tacggaagac tagcttggac
     6241 gagctaccac agttttataa tgttctaaag ggagatatga gtttggttgg cacacggcca
     6301 ccaacagtgg acgagtatga acactatacc ccagaacaaa aacgtcggct aagttttaaa
     6361 cctggtataa caggcttatg gcaggtcagt ggacgaagtg agattaagaa ttttgatgaa
     6421 gttgtcaaat tagatgtagc ctatatagac gattggacaa tttggaaaga tattgagatt
     6481 ttattgaaga cagttaaagt tgtattgatg aaggatggag cgaagtagat tgatagatgt
     6541 aaaaatcatt gtggcaacac ataaagaggt taaaatgcct caagacaata gtctttacct
     6601 tccaatacat gttggaagag acggtaaatc agatattggt tttatcggtg ataatactgg
     6661 cgataatata tcctctctaa atccatatta ttgtgagttg acgggacttt attgggcatg
     6721 gaagaatctt gattataatt acttaggtct agttcattac cgtcgttatt ttacaaataa
     6781 atctcaaggg tataatgaaa atgtcaatat ggatgacgtc attttgtctc gatctaatgt
     6841 tgaaatatta ttagagaaat ctgacgtaat agttccaaag aagcgaaagt attatattga
     6901 aactctttat tcacattatg cccataccct taacggagaa catctggatc ttgctaggaa
     6961 aattattgag caaaatagtt cagagtatct ttcatccttt gataaagtga tgaaacaaag
     7021 aagcggttat atgttcaata tgtttatcat gaaaaaagga ctattagatg attatttacc
     7081 gtggcttttt tctattctgg atactatgta cgaacagatg gacttgaccg actatacttc
     7141 atttgagtca cgtttattcg ggcgagttag tgagttgttg tttaatgttt ggttatgtaa
     7201 aaaaggaata acgcctaaag aggtaccatt tatgtacatg gagagagtgg atttgtttga
     7261 aaaaggaaaa tcttttttaa tggctaaatt ttttggaaag aagtatggac agagtttcta
     7321 ggagggaata tgaaaatcac tatcaaaagg tattcactgc cagaaatttt aggattagca
     7381 gcattagcta tattcctact attttcgtta ttaagtataa ctctttatgc ccaatatata
     7441 tctattaaag tatattttat tgcacttttt ggcattattt tattaatatt tctgaaggaa
     7501 cttatatctg agagttataa tcttaaatct gtgattggat tattcgtgat ttttactctc
     7561 tgcttcatca taggtaccgt cacgaattac gcatactttt ttattttagg tctgtttttg
     7621 atttatagtc ttagaaatct ccctttttca gacgtagcca aagtctcctt tatcattagt
     7681 attagtgtat tgctcctagt agtattgagt agtaagcttg gtattattcc tgattatatt
     7741 gagatttcgc ctaccagagt tagacactat cttggtttcc gatattcatt acttccatca
     7801 acgcttatga tgaatatcat agctatatca ttttttttaa agcaagaaaa cgcttcatat
     7861 ccgcgtcttc ttgtattgtt tttactttca ggatggttat acgtagaaac agattcacgt
     7921 ttgactttta ttaattcgtg tttgtttcta ctggttaatt taataatgaa attgtcacct
     7981 tccatcattg aaaaggtagg gagactgtta aaactttttt cgttcaccta ctttattaat
     8041 gcctgtttga gttactggat tgcgaagact tacttaaaca cctcaaatgt tgttttgaat
     8101 caattctttt accaagcgga tcaatttctt ggaggacgta tttattattc taatcgttcg
     8161 ttatctttat atggatataa gttgttaggt caaaagattg attggattgg aaatggcttg
     8221 agcatacaag gggagcgtag cacagaaaca tatttgtatg tggataattt atatatccag
     8281 attcttcaac attttggttt gatagtttcg gtaattattt taagtctatt aactataact
     8341 ttagtaaagc ttttgaaaaa ggggcagatg gtattaggaa ttattttagt tattttgagt
     8401 tttcatgctt taattgatga tttgatacta aatctatatt ataatatctt ttgggttttg
     8461 ataggaatgt tgatatataa aaaatatcaa ttttatgata aaaagcagtt gacaatagaa
     8521 taagaagcaa gcattggaaa tagacattca gatatgtaca agaaaactcg atttaagttt
     8581 tttggtaaaa tttttaaaat taagttgtaa aatggatatc aaaatctcac cttttttgta
     8641 ggtgtgatta aacagaggga tattagatag gaaaataatg aataagatta atttaactga
     8701 taatttaccg ttaatttcag ttgttttacc agtatacaac gtagagaatt atttagaaaa
     8761 gtgtttgaat tctgttgtga gacagacgta taaaaacata gaaattataa tagtaaatga
     8821 tggcagctta gattcttcaa tagatatttg taataagtat gcaaataaag atagtcgaat
     8881 taaagtattt acaaaaccta atggaggttt gtctgatgct agaaatttcg gtgtcaaaaa
     8941 atctatgggt gagtttataa cattcgttga ttcagatgac tatgttacag atgattatgt
     9001 agaatatttg tatagcttag tcaaaaaata taattgtaaa atgtcaatgt gttcaatatt
     9061 tgtccattat atttctaatg ataaaatgat caataatggg acaggaagag aattgatgat
     9121 gacagcagag cagtgtattg aaaaaatgtg ctatcatgat gaggtggata catgtgctta
     9181 tgcaaaatta tatcatagaa gtctatttag tgaaatatgc ttccctaaag gaaggatatt
     9241 cgaagatatt ggaacaattt atcgcttttt tggtactgct gggcagattg cctgtggttt
     9301 taacgcaaaa tattattatg agattcggga aaattcgatt gttacatcat catttagtga
     9361 aaaaaaattt gatttgttat ttatgacaga tcaaatgcga aattttgttg atcaacgtta
     9421 tccatctttg aaagctgcaa caaaacgtcg agctgtctat gcaagattta gtacccttaa
     9481 ccaattatta gatgtacaag gatataatga agaaaaaaaa gaaataattc gttttatcca
     9541 agacaacaag gaagcgttac ttgaaaatcc taagactcct aagcgggata gattagctgt
     9601 tagagctctc tcccttggat tttgcattta taaattgtta tggaagcaat atctaaaaat
     9661 tcaaagaggt tagtatgaat aaagaatttt tgaagtatat ttatattcga ttattaagaa
     9721 atttaaggag aattttcttt attatcccga taataaggaa tagagttgtt tttgaatctt
     9781 tctcaggaga tgcttatagt tgcaatccta aatatatttc tgaagaatta agaaaacagt
     9841 atggtgattc tgttgaaatt atctgggctt ttaatgatcc aaacaaattc aaaaaagaat
     9901 taccaaagga gattgtgact tgtcgttacc gtagtttcaa tcatctgatc tatagaatca
     9961 cttcaaaagt ttatgtttgt aatttcctgc aagcaattga aattccaaag cgtaaaggac
    10021 aactagagat tcaaacttgg catggaggag gttgctataa aaaagttggg gtggctgaaa
    10081 aaggacgcca ggctgcttat gttaaacgac aacggatgca cgttgaagaa acagatctct
    10141 ttattacaag tagtaaatat tttgaaaatg aggtagtaaa aaaacaattt gggtataagg
    10201 gagaaatttt atctattggt atgcctcgaa atgatatttt aataaattta ccaatttcaa
    10261 gtcaagttga gaaattaaag gagaaattgg gattaccaaa caataaattg atagcacttt
    10321 atgctccgac ctggagatca ggtactaaac agtatgaaac acttgatata aaaaaactta
    10381 ctcaagccgt tgataaaaaa tttggtaaaa aatgtatcgt tcttttcaga tcgcatctat
    10441 atggaaatca atcttatgat gatgttgtgg atgtctctca gtatagtgat atgcaagaat
    10501 tattgttgct ttcagatata ctgattactg actattcttc gtctatgtgg gatttctctc
    10561 tctcttttaa accgtgtttt ttatataccc ccgatttgaa ggattatcta gatgaaagag
    10621 gttttgatga agatatacat tcatggggat tttcagtttc tgaatcaaat aaggaactag
    10681 ttgaaaatat tttacagttt gataatgaag aatatagaca aaaaatgaag aatcatcatc
    10741 agtttttaga atcttatgaa caaggagatg cagcgaaaag agtcgtggcg aagattgctg
    10801 aatattgtaa tttatataga ggatagataa tgaaaaaaat tgcttatttg atcaaaagat
    10861 atggtgtgaa aaatgtggtt ttacgtgcta ttaatgatgt tctaccagtc aatctcatct
    10921 ttcccagtca acaactcaga cgtttgaatt ggcaagaaaa agtcaaaaag aagttaaaaa
    10981 aatatgtagt tatttcggat tcaatcaaga gtgaggagga atgcgatatt atctggtggc
    11041 tatggtttca aggacttgat aatgcaccag ctattgtgaa aaaatgtaga gagtcggtag
    11101 ataaatatgc taaacgcagt ggcaaaaggg ttattgagtt aacatctcaa aatttatttg
    11161 aatatattga ggtacctaac gaactctatg tgaaatataa gtcaggtagt ttgccactag
    11221 ctttattttc agatttttgt cgaattagcc ttctttctaa ctatggagga ttatggattg
    11281 attcaactgt tctaattacg ggggaaattg aagatgagat attgaaccaa gatattttta
    11341 tgtttcaagc ttctccttta gactattcag ttactaaaat cagtaattgg atgttatatt
    11401 caaaatatcc aggacacccg ttcatatcat cgatacgtga tactttgatt tcattttata
    11461 ataagaataa tacgatccca gattattttt tatttcattt acttgtttcc tgtttaatag
    11521 atgataatag gataaatcaa agtttttatg atatggatta ttataccaat acctatcctc
    11581 acttattagg gagagttttg agcgaaccat atgatacttt gaaatttgaa aatattttaa
    11641 ggaaaacgtc tattcataaa ttatcatata aaaatttaga taatgttgct gaagatagct
    11701 tttataatgc tattttaggt ttagatttta gttagtaata aagaggagag aaatgaattt
    11761 agcagttatt tttgctggag gctccggtac gcgaatgaat gcaaaggata gacctaagca
    11821 gtttcttttg gtacatggta agccaattat tgttcacact attgagctat ttgagaacca
    11881 tccagagatt gatggaatta tcgttgtttg tattgaagat tggattccgt atatggagga
    11941 gatgaaatat tgctatagat tagataagat tgctaagatt gttccagggg gggcaactgg
    12001 tcaattatct atttataatg gtttagtcgc ggctgaacaa ctttatggaa tagaggataa
    12061 tgttgtgtta atccatgatg gagtccgtcc tttaattaca gcagacacta tttcagataa
    12121 catccaatcc gtaaaagaaa agggaaatgc tattacttgt acagtggcca aagaaacagt
    12181 tatcttagta gatgatgaaa ataaggtaga cgaagtgcct agtcgtgaac attcgcgatt
    12241 tgccaaggct cctcagagtt tttggctaaa agatattcta ggtgcacatc gagcctctgt
    12301 agataatggt agaaataatt ttattgattc atgcaccatg atgagatatt atggtcatga
    12361 tttacatgtt gttgttggtc cgtatgagaa tattaagatt acaacgcctg atgattttta
    12421 tacatttagg gctttgtacg atcttcgtga gaataagcaa ctaaaataat gaggaaaaga
    12481 tgaagtattt tgttgaagaa acgttacttg atgaacagga taaaaaaaat gcgggtggaa
    12541 aggctagaca agacgtcact gatattttag agtccatagg ttatcagaag ttaatagctg
    12601 agtccgaaat gaatgaacgt caggaattaa atgctgttca aagattggtt catcattata
    12661 aagttaagaa aatgtggaag aaaactcttt cagttgttgg taagggtgat gaagttatta
    12721 ttcaatttcc tttactaaat catagtttat tctttaatca ggttattaag caacttagta
    12781 agaatggagt taaagtttat tttttgattc atgatttaga atcgttgcga tggtcgcagt
    12841 caaaatcgat atcattaaaa agtaggattc gattaaacat tgaagaacat agtgttttaa
    12901 ggttatcaga aggcattatt gctcataata aaaaaatgaa atcttatatt aagacctact
    12961 ctgttgaaag ttctaaaatt attcctcttg aaacttttga ttatattatt ccatcttatc
    13021 atgaaagaaa aaatctggat aactttcagt taaatgctcc aattgttatt gctggaaatt
    13081 taaagcaaca taaagctgga tatgtctatc atttaccaag caatgtggag tttaatcttt
    13141 atggaattgg atatgaacag acagatgaca aaagtgtgca ctactgtggt tcttttatgc
    13201 cagaagaatt accattcgtt ttaaaaggaa gttttggatt ggtatgggat ggtccgtcat
    13261 cagagtcttg tatagaaact tatggagagt atcttcgtgt aaacaaccct cacaagactt
    13321 cactatattt agcttcaggc ataccagtag ttgtatggtc agaggcagca atagctagtt
    13381 tcattaagga gaataattgt ggtattcttg tatccaatct gagtgaacta cctgagttac
    13441 tttctatgat taccgttgat gaatatgaat tgatgaaaaa gaatactgag attattggag
    13501 aaaggcttcg acaaggtttt tatactaaac aagcagttaa aggtttctag actggaggaa
    13561 gtgtaatgat tgaaagtttt aatgataaag tgttgcagga agatttagag ataattgcaa
    13621 aagaagagct cccatttcga aaatttagaa attcaactgt ttttatcacg ggagtaacag
    13681 gtttagtagg ccttcaatta tttaaggctt tggcttgtat caatagagtc catcagttga
    13741 atatgaaaat tattggtcta gtcagaaatt tggataaagc agaaaaaatt tttggagatt
    13801 tattgaaacg gaaggatata caaatagttt taggagatgt ttcggaagat ttccactcgt
    13861 atatccctga tggtttagtt attgactata tcattcacgg agcaagcgtg actacctcta
    13921 aactcatgat tgaatttcca gtagatacaa ttcgagtagc ttttaatgga acgtatcaaa
    13981 tgttagaatt ggcaaaagaa aaaaaagtga aaagttttgt atatctttct tcaatggagg
    14041 tatatggtag ctttcagtca gatagaacaa ctgttgtaaa cgagaatatg ttagggtatc
    14101 ttgatttgac atctgttcga acaaattacc cagaatgcaa aagaatttgt gaaaatatgt
    14161 gcattgcatt tctaagtcag tatcaagtcc cggctaagat tgctcgtcta tcccagacct
    14221 ttggtgcagg cactctaccg ggtgaaaata gagtatttgc tcaatttgct cgtagtgtta
    14281 tgcaagggaa agatattgtt ttacatacgt tagggcaatc agaaggaaat tactgctaca
    14341 cagctgatac tgttgttgca ttattaacaa ttctattgag aggagaaaat ggggaggctt
    14401 ataatattgc taatgaagag agtcatacaa caatagcaga tatggcaaaa atggtaactt
    14461 cgcaattctc tcaaacgagt caagtggttt ttgatattcc gaagaaaaat atatttggtt
    14521 atgctgtaga tactaaaatg aagttatcaa cacacaaaat tcaacaattg ggttggaagc
    14581 cgagggtctc tcttgtagat gcttatgatc gaatgatgag aagtatgaat gaaactgggg
    14641 tatagataac tatatgaagg tattaaaaaa ctacttatat aatctctctt atcaactatt
    14701 agttattatt cttcctatca ttacgactcc ttatgtgacg cgcatatttt cttcagatga
    14761 tttagggaca tacggttact tcaattccat tgttacctac ttcattttac ttgctactct
    14821 gggtattgct aactatggaa cgaaggagat atctgggaat aggaagagta ttcagaaaaa
    14881 tttctgggga atatatactt tacagtttgg agcgactact ttttccattt ttctctatat
    14941 actagcctgt cttttcatcc cagggatgaa aaacctagtt gcatatatct tgggattggg
    15001 tttagtctct aaaggactag atatttcatg gttgtttcaa gggttagaag attttcgtaa
    15061 aattacggtc agaaatatca cagtgaagct tgttggtgta agtgccattt tcttgtttgt
    15121 aaaatcagcg agtgatctat acttgtatgt ttttcttcta acagcatttg aattgttggg
    15181 tcagttaagt atgtggtttc cagcccgtga atatattgga aaaccacatt ttgatataga
    15241 atatgctagg catcatctga agccagttat cttgctattc ttaccacaaa ttgctatctc
    15301 gctttatgtg actttagatc gtacaatgtt aggggcgcta gcttctacaa aagatgtcgg
    15361 catttatgat caggctttga agctggttaa tattttactg accttggtaa cttccttggg
    15421 aagtgttatg ctgccacgcg ttgcgcattt gttagcgaca ggtgatcata aggtagtcaa
    15481 taagatgcat gaggtatcct tcttaattta taatttggtt atttttccga ttatggcagg
    15541 gatgttgatt gtgaatgatg attttgttca atttttcctt gggcaagact ttcaagatgc
    15601 acgctatgca atttccatta tgatcttccg tatgttcttt atcggttgga ctaatataat
    15661 gggaattcag atactgatac ctcataatca aaataaagaa ttcatgattt caacaacaac
    15721 tcccgcaatt atcagtgtag gtttgaactt actattcctt cctaaactgg gatatatcgg
    15781 ggcagccatt gtctctgttt taacagaggc acttgtatgg gcaatccaat tattctatac
    15841 tcgcagatat ttaaaagaag ttcctataat cggatcaatg tcaaaaatta tactagcatc
    15901 tgccattatg tatggccttt tactaagttc aaaaacagtt atacattttt caccgacctt
    15961 aaatgttcta gcatttgtag cgcttggtgg aatcatttat ctttttgcaa ttctatctct
    16021 gaaagtggta gatgtgaaag aattaaaaca aattattagg aaaaactaga atgagaaaaa
    16081 atcgaaatat caacctagat ttactaaaag tgcttgcatg tgttggagtt gttttacttc
    16141 atacaacaat gggcggattt aaagagacag gttcatggaa tcttttggca tatttatatt
    16201 atttaggtac ttactctatt cccttgtttt ttatgatcaa tggttatttg ttgttaggca
    16261 agagggagat aacttatctt tacatactcc agaaagtaaa atggatttta ataacagtgt
    16321 catcatggtc atttatcgta tggcttttta agcgtgattt tacaactaat cctattaaaa
    16381 aaattgtagg ttctttgata caaagaggtt atttctttca gttttggttt ttcggtgcac
    16441 tcatacttat ctatttatgt ttgccaattt tgagacaatt tctaaattca aaaagaagct
    16501 atttatacag tttatcttta ttgatgacta ttggtttgat ttttgagtta tcaaatatcc
    16561 tacttcaaat gccaatacaa acatatgtaa tacaaacttt tagattatgg acgtggtttt
    16621 tttactatct tttaggtggt tatatagcgc aattcactat agaagaaatt gaatcaaggt
    16681 ttaagaattg gatgaaaata gttagcatac ttttgttatt gatttcacca ataatattat
    16741 ttttcatagc gaagactata taccataatc tatttgctga atacttttat gatactttat
    16801 ttgtaaaagt cagtacttta ggaatttttc taactatcct catgcttact ttgaatgaaa
    16861 accgaagaga atcgattgtt tccctttcta atcaaacaat gggggttttc ataatacata
    16921 cttatattat gaaagtgtgg gaaaaagtgc ttggttttaa ttttgtagga gcatatttac
    16981 tttttgctct atttacttta agtgttagtt ttattattgt tgggatgtta atgaagattc
    17041 cttacttcaa tcgaatcgtc aaattataaa aaggagaaca agatgtacga ttatcttatt
    17101 gtcggtgctg gtttgtcagg agcaattttt gcttatgagg cgaccaagcg tggaaaaaaa
    17161 gtaaaagtga ttgataaacg taaccacatt ggtgggaata tctactgtga gaatgtagaa
    17221 ggagttaatg ttcataaata tggtgcccat atctttcata cttctaataa gaaagtttgg
    17281 gattatgtta atcaatttgc tgaatttaac aactacgtca actcgcctgt agctaattac
    17341 aagggtagcc tctataatct acctttcaat atgaatacct tctatgctat gtgggggaca
    17401 aaaactcctc aagaagtcaa agataagatt actgagcaga cagctgatat gaaggatgtt
    17461 gagccgaaaa atctggaaga acaggctatc aagttgattg gtccagatgt ctatgaaaag
    17521 ttaatcaagg gttatactga aaagcagtgg ggacgctcag caacggaact tcctccattt
    17581 atcattaaac gtcttccagt tcgtttaaca tttgataata actattttaa cgaccgttac
    17641 caaggaattc ctattggtgg ttacaatgtc atcatcgaaa atatgcttaa agacgttgaa
    17701 gttgagcttg gtgttgattt ctttgctcat cgtgaagagt tagaagcatc agctgaaaaa
    17761 gttgtcttta cagggatgat cgaccagtat tttgactaca agcacggaga gttagaatac
    17821 cgtagccttc gctttgatca tgaaattttg gacgaggaaa attatcaagg aaatgctgta
    17881 gtgaactata cggagcgtga gattccttat actcgtatta tcgaacacaa gcattttgaa
    17941 tatggaacac aggcaaagac agttatcacg cgtgaatatc cagctgactg gaagcgtggg
    18001 gacgagcctt actatccgat caacgatgag aaaaataatg ctatgtttgc taagtaccaa
    18061 gaggaagctt caaagaatga taaggttatt ttctgtggac gtttagcaga ttataaatat
    18121 tacgatatgc atgtggtgat tgaacgggcg cttgaggttg tggagaaaga gtttggatat
    18181 gacaaaaagt agaatcaatt ggatagattt tggaaaaggc ttttccatat ttttagtctt
    18241 agcaggacat gtgttgcttg gactgtatca atcggaaaaa tttcccacag caaataacat
    18301 actatcgttg ttgatagcac aagtctacat atttcatata ccagtatttt ttgccttatc
    18361 aggatacttt ttcaaacctg tgtcggattt gaaggagttc tggcaatatg ctaaaaagaa
    18421 gacaattgtt tttggtctgc catatatttt ctattcgatc attcactttg gtcttcaaaa
    18481 agttgcaggg gcatctgttc gtgttcctac aaccatatct gatttgctaa atatctataa
    18541 acatcctctt ggagtttcat ggtatttata tatactctgg tcgattttga taatctatgg
    18601 attattgtct attttagtca aaaatcgtag aatgttattt ttgataagtg ttttcgctta
    18661 ttgtttaacc ctatttgttc aaacagatat ttatattatt caaagaacgc tagtttgggg
    18721 gatttgtttc tttcttggca gtgtattgag tgaaattcac tttgataaaa ttaatttgaa
    18781 aaaatttctt tttttctttg tgttatttga ttttatttat atgttcgctt ggttcttgtt
    18841 ttatgaagta gggtctaaga aggattatgt aagctatatt aacccaggtt tgtgggggat
    18901 tgcttttatt gtctgtgtat tagttgcttt tgcgattttt cctaaaatgg agaaaaattt
    18961 tcctaaaact ttcctatatt tcactaaata cgggaaagat agtttaggga tctatattct
    19021 tcatgcacca atttgtagca tgattcggat tctaatgttg aaagtgggaa taaactcagt
    19081 ttttcttcac gttgttgttg ggattgtgct aggctggtat ttatccatac tagcaactta
    19141 tatattgaaa aaaattccat ttttgaatat tgttttatta ccacaaaagt atattaaatt
    19201 aaaataaatt attttagatt tataatgtgg ctctttgtca actaacatct ggagaggaca
    19261 atcactgtct tctctttttt tgtcttttca gaatatacca aattaacaca aaaattctga
    19321 aaattctgtt gacatctttc tgaaaagagt ttataatgga gagaaagttt taaaggagaa
    19381 aatgatgaaa agttcaaaac tatttgccct tgcgggcgtg acattattgg cggcgactac
    19441 tttagctgca tgctctggat caggttcaag cactaaaggt gagaagacat tctcatacat
    19501 ttatgagaca gaccctgata acctcaacta tttgacaact gctaaggctg cgacagcaaa
    19561 tattaccagt aacgtggttg atggtttgct agaaaatgat cgctacggga actttgtgcc
    19621 gtctatggct gaggattggt ctgtatccaa ggatggattg acttacactt atactatccg
    19681 taaggatgca aaatggtata cttctgaagg tgaagaatac gcggcagtca aagctcaaga
    19741 c
//
