LOCUS       CR931710               30298 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 9687/39 (serotype 38).
ACCESSION   CR931710
VERSION     CR931710.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30298)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 30298)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..30298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="9687/39"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC38_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC38_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34394.1"
                     /db_xref="GOA:Q4JZD8"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4JZD8"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAP
                     WDAFCVELL"
     gene            order(322..1752,1788..2273)
                     /gene="aliB"
                     /locus_tag="SPC38_0002"
                     /pseudo
     CDS             join(322..1752,1788..2273)
                     /gene="aliB"
                     /locus_tag="SPC38_0002"
                     /note="member of homology group 169"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     misc_feature    join(538..1752,1788..1871)
                     /gene="aliB"
                     /locus_tag="SPC38_0002"
                     /note="HMMPfam hit to PF00496, Bacterial extracellular
                     solute-binding prot, score 1.3e-37"
                     /pseudo
     gene            complement(order(2414..2998,3052..3225,3228..3740))
                     /gene="tnp"
                     /locus_tag="SPC38_0003"
                     /pseudo
     CDS             complement(join(2414..2998,3052..3225,3228..3740))
                     /gene="tnp"
                     /locus_tag="SPC38_0003"
                     /note="member of homology group 13"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
                     /db_xref="PSEUDO:CAI34396.1"
     misc_feature    complement(join(2918..2998,3052..3225,3228..3284))
                     /gene="tnp"
                     /locus_tag="SPC38_0003"
                     /note="HMMPfam hit to PF01610, Transposase, score 8.5e-33"
                     /pseudo
     gene            3892..4275
                     /gene="tnp"
                     /locus_tag="SPC38_0004"
                     /pseudo
     CDS             3892..4275
                     /gene="tnp"
                     /locus_tag="SPC38_0004"
                     /note="member of homology group 19"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase (fragment)"
     gene            complement(4295..5248)
                     /gene="tnp"
                     /locus_tag="SPC38_0005"
     CDS             complement(4295..5248)
                     /gene="tnp"
                     /locus_tag="SPC38_0005"
                     /note="member of homology group 39"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1239 transposase"
                     /protein_id="CAI34398.1"
                     /db_xref="GOA:Q4K0X9"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="UniProtKB/TrEMBL:Q4K0X9"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     misc_feature    complement(4304..4741)
                     /gene="tnp"
                     /locus_tag="SPC38_0005"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 6.6e-23"
     misc_feature    complement(5102..5167)
                     /gene="tnp"
                     /locus_tag="SPC38_0005"
                     /note="Predicted helix-turn-helix motif with score
                     1087.000, SD 2.89 at aa 28-49, sequence
                     KSNREIAGLLGKAPQTIHNEVK"
     gene            5802..6899
                     /gene="glf"
                     /locus_tag="SPC38_0006"
     CDS             5802..6899
                     /gene="glf"
                     /locus_tag="SPC38_0006"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34399.1"
                     /db_xref="GOA:Q4JZ57"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ57"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRNHIGGNIYCEN
                     IEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKNKIAEQTAHMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TDLPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFANRQ
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEVLDKENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQDKTVITREYPADWKRGDEPYYPINDERNNAMFAKYQEEAVQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVRNEFS"
     misc_feature    6237..6839
                     /gene="glf"
                     /locus_tag="SPC38_0006"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 1.1e-135"
     gene            7217..7897
                     /gene="wzd"
                     /locus_tag="SPC38_0007"
     CDS             7217..7897
                     /gene="wzd"
                     /locus_tag="SPC38_0007"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34400.1"
                     /db_xref="GOA:Q4JZ56"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ56"
                     /translation="MNNRIVDISLFDLLNVLWLRKWIIVFVSFVFGCISFLYYQFFVP
                     KTYTSDTRIYVVSKGDNKNLSNADLQAGSALTKDYKEIILSDEVLEETISDLKLESTL
                     ESLASKIKISIPAETRIISISVTNTNSDEAARIANGIRKVAALKIKEVTQVTDVTTLQ
                     TARPPQTPSGPHVRKSTTAGLVLGAFLTVFLVVAKEILDDRIKRFEELEKLGIPILGS
                     IPLSKNIK"
     misc_feature    7232..7642
                     /gene="wzd"
                     /locus_tag="SPC38_0007"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 2.5e-41"
     gene            7904..8593
                     /gene="wze"
                     /locus_tag="SPC38_0008"
     CDS             7904..8593
                     /gene="wze"
                     /locus_tag="SPC38_0008"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34401.1"
                     /db_xref="GOA:Q4JZ55"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ55"
                     /translation="MGKLELTRKYYQLYNETKEYFNALQTNIQLSGDGLKVISVTSTV
                     KNEGKSTISVGLSMSLALSGYKVLLLDVDLRNSVMSGMFHSRERITGLTEYLSGKAGM
                     ADSMQETTLDNLYILQAGVVSPNPLSLLRSVKFETLIDSMKKYFDYIIVDTPPIGQVI
                     DAAIIAQQCDGIFLVTEMRKTTRRQIFSSLQQLEQTGVPVLGLVANKAIIKKDSYGYY
                     GKNTASETERY"
     gene            order(8703..9092,9118..9183,9188..9508)
                     /gene="tnp"
                     /locus_tag="SPC38_0009"
                     /pseudo
     CDS             join(8703..9092,9118..9183,9188..9508)
                     /gene="tnp"
                     /locus_tag="SPC38_0009"
                     /note="member of homology group 19; member of homology
                     group 19"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
     misc_feature    join(9030..9092,9118..9183,9188..9496)
                     /gene="tnp"
                     /locus_tag="SPC38_0009"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 7.9e-11"
                     /pseudo
     gene            9726..11177
                     /gene="wzg"
                     /locus_tag="SPC38_0010"
     CDS             9726..11177
                     /gene="wzg"
                     /locus_tag="SPC38_0010"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34403.1"
                     /db_xref="GOA:Q4JZ54"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ54"
                     /translation="MRYFMSREKKRGTAVHLKSYINSVLLILYTGIASLFLFQIFRYN
                     ILNFRNLNLLVALLVVLVFILGVSLIVRKKAEKLTMLLLILAVASSSISLLAVQQFIG
                     FTSRLNATSNVSEYAISLVVLKDSEISELEQVSHVMAPTDTDYEAIQSLLADIKEKQG
                     KDLIVDKSKSYLEAYKSLISGDTKVIFLNSIFEHMIESDFPDFRDKIKKIYTKEMTKK
                     VEAPKVSKGQTFTIYFSGIDTYGPINSVSRSDVNILMTVNSETKKILLTTTPRDSYVA
                     IADGGKNQKDKLTHAGIYGIDSSIHTLEHLYGVEINYYVRVNFTSFLKIVDLLNGIDV
                     DNSQEFTIDGNDYPVGNLHLNSKSALGFVRERHSLADGDRDRGRNQQKVLAAIIQKLT
                     SIESLKNYRQIMQGLEDSIQTNLSPTTIMDLANTQLESGGNYKINSQDLKGTGRMDLP
                     SYAMPDSQLYMMEIDENSLSAIKENIQAVLEGR"
     misc_feature    9942..10289
                     /gene="wzg"
                     /locus_tag="SPC38_0010"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 9.5e-40"
     misc_feature    10467..10904
                     /gene="wzg"
                     /locus_tag="SPC38_0010"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 2.5e-65"
     gene            11116..11910
                     /gene="wzh"
                     /locus_tag="SPC38_0011"
     CDS             11116..11910
                     /gene="wzh"
                     /locus_tag="SPC38_0011"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34404.1"
                     /db_xref="GOA:Q4JZ53"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ53"
                     /translation="MMRIASQLSKKIFRLFWRVGKMIDVHSHIIFDVDDGPKSIEDSR
                     ALLLEAYDQGIRTIVSTSHRRQGMFETPEDKIAENFRAVQKIARDIADDLTILYGAEI
                     YYTQDIINKLEKKTFPTLNGSRYALIEFSSETSYRSIHSALQQLLLSGITPLIAHIER
                     YDALENNKQAVLELIRMGCYTQINSSHLLKKKLFKDDAKIMKKRVHYFLKHDLVHIVA
                     SDMHNLDTRPPYMAEAYEIISKRYGKEKAEEFFIKNPQRILMDQLI"
     misc_feature    11182..11790
                     /gene="wzh"
                     /locus_tag="SPC38_0011"
                     /note="HMMPfam hit to PF02811, PHP domain, score 3.6e-36"
     gene            11929..12516
                     /gene="wciI"
                     /locus_tag="SPC38_0012"
     CDS             11929..12516
                     /gene="wciI"
                     /locus_tag="SPC38_0012"
                     /note="member of homology group 29"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34405.1"
                     /db_xref="GOA:Q4JZ52"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ52"
                     /translation="MYKVIKRFIDIALALLGIVLLSPLFLGIIVFIKLESKGTIFFKQ
                     KRIGLHKKEFYILKFRTMRIDTPSAVPTHLLKNPYQWITKVGKVLRRTSLDELPQIWN
                     ILVGHMSLVGPRPALWNQFDLIEERDKYGANDILPGLTGWAQINGRDELSIPVKAKFD
                     GYYVKNCSFVLDCRCVVESFLVVFKRYGHREGGAD"
     misc_feature    11929..12030
                     /gene="wciI"
                     /locus_tag="SPC38_0012"
                     /note="Signal peptide predicted for SPC1774 by SignalP 2.0
                     HMM (Signal peptide probability 0.966) with cleavage site
                     probability 0.674 between residues 34 and 35"
     misc_feature    11944..12498
                     /gene="wciI"
                     /locus_tag="SPC38_0012"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 1.1e-31"
     gene            12529..13659
                     /gene="wcyA"
                     /locus_tag="SPC38_0013"
     CDS             12529..13659
                     /gene="wcyA"
                     /locus_tag="SPC38_0013"
                     /note="member of homology group 170"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34406.1"
                     /db_xref="GOA:Q4JZ51"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ51"
                     /translation="MGNRKKVFVVANVVKEHILKFHIPTIKEMTKRGWTVDVGASGDE
                     TVPYCHQQYSLPHQRSPFHLGTLKSIWKLRKILKSGGYDIVYCHTPVGGLVGRLASLG
                     LRKQGTRVIYFVHGYHFYKGATFFNWLVYYPIEKLLSLFTDSIILINQEDYHLTKTKF
                     KQVQSYLVSGMGVKQERFSPQSNQVRERYRKELKLPEDATVLIYCAELIKNKNQTFLL
                     HAMKKLVDQGENLYCLLVGIDYTKGEMVEYIQSLNLSDRVLLLGWREDIANLYACSDI
                     CVATSIREGFGLNIVEAMFCHVPVVATINRGHASIIQDGQNGLLVQLGNTKQLVEAIY
                     VLMKDTKKKQELVEQASANLEQYHSQKIVNSLLEIIEQTAMK"
     misc_feature    13084..13599
                     /gene="wcyA"
                     /locus_tag="SPC38_0013"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 2.6e-41"
     gene            13656..15086
                     /gene="wzy"
                     /locus_tag="SPC38_0014"
     CDS             13656..15086
                     /gene="wzy"
                     /locus_tag="SPC38_0014"
                     /note="member of homology group 171"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase Wzy"
                     /protein_id="CAI34407.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ50"
                     /translation="MSEGCEKVKIQIDKIYYLFFWLVVSFGYFFMMPTFTEDLEGVVS
                     ASLVQLLLFIIGYVYVSYLNRSFISLYSIFMIVFYLFQNGQVLLYSLGVEYDYFYVLR
                     YDETIVLQSVIFSTQCLIAAFMAGVFSTKKEVSKPLYSYMDQLEREKLITTGKLFWGA
                     FAIFALPFMMMKLVITSTSGYFAMIRFVGSLPTITVLFEKMFIASSVFLIVYLKSEET
                     WSKFLKVVILGWSIMAALTGDRTVGLAGIVTLALIQTLIGNRKKKIKFSQYALLVGAA
                     VVVMYLMSFAFQFRMQQDSKVSGLQTAVVEMIGTLGFSFFPLVLTIRIVPTSINFFRG
                     KSYIAAIITGLIPSNFDFLHLTNTLSEWNAYPTELLDTIYHYGFGLDYSLIAEAYINF
                     GSYGWIAIFFLCSLIAYFVRDVDFKRKDNLFSQYASLILLYSWFTLPRRKSYFIFNNF
                     FWYVLFFGLALILVSRSIKQRKEFKK"
     gene            15083..15850
                     /gene="wcyB"
                     /locus_tag="SPC38_0015"
     CDS             15083..15850
                     /gene="wcyB"
                     /locus_tag="SPC38_0015"
                     /note="member of homology group 172"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34408.1"
                     /db_xref="GOA:Q4JZ49"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ49"
                     /translation="MKISIIMGIHNGEKRFETAVQSIFNQTYDNWEFIICDDASTDKT
                     FEKLQGLYGQDSRFILLKNEKNVGLSATLNRCIEASSGEFIARMDDDDICYPERFERQ
                     VDYLFHHPEIDFVSSSIDIFDGEVVVGTRILLDFPSKKDLIWNSPFVHPVTMFRRDAL
                     LEVGGYRVSPETVRGQDYDLFMRLYSCEKKGGNILEPLFRYTIDQNTMKRRTFKARIG
                     EMIIRYKGYRAMKVPFYNYVFIFKPLVAHLVTLVKRR"
     misc_feature    15092..15574
                     /gene="wcyB"
                     /locus_tag="SPC38_0015"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 3.2e-39"
     gene            15850..17031
                     /gene="wcyC"
                     /locus_tag="SPC38_0016"
     CDS             15850..17031
                     /gene="wcyC"
                     /locus_tag="SPC38_0016"
                     /note="member of homology group 173"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34409.1"
                     /db_xref="GOA:Q4JZ48"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ48"
                     /translation="MFMKILITTHTYLPNKDGVQFVNQYLAEGLVKRGHQVTVLTYCY
                     PSRTRVPREVINGVRVIRWNARTSCTFHKGEKLAYQNFILNSQSDYDVLVNVGTQTAL
                     TDWLFPIFSQLTIPKVLYIHSIWDFNWLHWHRQSFKRFVAKAWANVRWKYYYWTKASI
                     FKQYHEVIQLHPKDYSVAFFKEKYGIESQILENAADASFFQNRNAVKKQSYIVNVSNF
                     NDRKNQKKAVEYFLKSNLPNEWKLVLVGSEKNQYLQSLQTFEKELRNQLGITSGKEIE
                     YRIGLSREEVVKTVKEASFCLMTSIWEAFPISLIEVMAAGIPFISSDVGIVNYLSGGI
                     TACSDQEFIRAIEEFASCPEIRNQYGKKGQMEAKEHYQVDDKVKELEALLQKVVKEEK
                     E"
     misc_feature    16435..16947
                     /gene="wcyC"
                     /locus_tag="SPC38_0016"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 7.5e-15"
     gene            17028..17993
                     /gene="wcyD"
                     /locus_tag="SPC38_0017"
     CDS             17028..17993
                     /gene="wcyD"
                     /locus_tag="SPC38_0017"
                     /note="member of homology group 174"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34410.1"
                     /db_xref="GOA:Q4JZ47"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ47"
                     /translation="MKKIVFLCPYFGTLPPHTQLWLNSCKMNPSVTWYLFTDDKRKFD
                     YPENVQVFYTTLEETKALYQKKFDFEISLEGAYKLGDYKPLFGYLYEEMIQEFDAWGH
                     IDVYDEIYGDIRAFVTDELLEKYDKLMIFGHMGIYKNSPEVNRRFELSSDLNRTYQEI
                     FSSSQFYNFEEYVAGSITRIYQKNGFPIGKLDEVIADLSGTSYHFRRGYISDDFETFT
                     YLPYEPMIFSWEEGKTYCYSVKNHQVQKDEFMYVHFKRRKMIQDIPDDASTYLIVPSG
                     FALMPEEITVDLIRKYSQKKLFYPVYFEEKWKGFKRLWNKIWRSE"
     gene            17990..18871
                     /gene="wcyV"
                     /locus_tag="SPC38_0018"
     CDS             17990..18871
                     /gene="wcyV"
                     /locus_tag="SPC38_0018"
                     /note="member of homology group 187"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34411.1"
                     /db_xref="GOA:Q4JZ46"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ46"
                     /translation="MKNILKKLIQQLPDKLFLQIKYFYIFKKKLNLKNPKTFNEKLQW
                     LKLYDRNPFYTILADKILVKDYIAKTLGEEYVIPTLGVYHHFDEIDFDELPNSFVMKT
                     NHDSGSIIIVKNKEDLNIQEAREKLQKSLERDYFIFGREWPYKNIERKIIIEEFMTDE
                     SNQELKDYKIYCFNGLPKFVHVDYDRFTNHKRNIYDSNWKQQEFMYAFPSDKNKTIEK
                     PAELSEMIELVRKLSKEMPFVRCDFYIVNHKILFGEMTFCPGSGFEKFYPEQYDVEFG
                     KDITLPEKHEWKQKKNV"
     gene            18847..20262
                     /gene="wzx"
                     /locus_tag="SPC38_0019"
     CDS             18847..20262
                     /gene="wzx"
                     /locus_tag="SPC38_0019"
                     /note="member of homology group 176"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase Wzx"
                     /protein_id="CAI34412.1"
                     /db_xref="GOA:Q4JZ45"
                     /db_xref="InterPro:IPR002528"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ45"
                     /translation="METKEKRLVHNTIIFTIGSLGSKFIQFLLVPLYTYTLTASQFGI
                     TEILLTAVNLLIPVFSISIADGLLRFGLDKTLRRENVLKSAFIISILGTILSIISIPI
                     FSLYPTLSEWMVYFIIILNLRMYRDVFAIQLKVEGKNTLFACDSMIYTFVLSLASIVF
                     LVPFSLGISGYFFAYIVSNGISIFFILFFGGVWKSFTSGRFEKQLMIQLLKYSAPMIL
                     NGIAWWITNASDRFMLQWFMDDRAVGLYGVVAKLPLLIGTFTGVFNQAWIISAVEEFE
                     EENEEWFYQKVFHQYYAALFLSVSVFLLLLQPFMKVYVSPSFYEAWQYAPFLLLSSVV
                     SGIAAFMTGFYVAQKKNLNIIYTTIAGAFANILLNAMFIPMLGVLGASIATFLSWFVI
                     AIYRMKDVENFACFPLDKKVFWYLFLLCIQTITMTFLPILGIVFSVVLIPYFFYQEQE
                     FLAVLFDKGRKKVCSFKKSKR"
     misc_feature    18868..19671
                     /gene="wzx"
                     /locus_tag="SPC38_0019"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 8.3e-10"
     gene            20235..20897
                     /gene="wcyF"
                     /locus_tag="SPC38_0020"
     CDS             20235..20897
                     /gene="wcyF"
                     /locus_tag="SPC38_0020"
                     /note="member of homology group 177"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAI34413.1"
                     /db_xref="InterPro:IPR015037"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ44"
                     /translation="MFIQKIKKIIRVFLRKSLVKDYRQRIQNKEFTLITSNCVGGLIS
                     HDLGLQFRSPTINMYIEAADFIQFCSHLERYLKEDLSFIEVNQDGHFVALCGDIKIYI
                     VHYNSFEEFAKKWSERAKRVDFDQLYLMMSERDGCRYEDIVKFDTLPYKNKVIFTSKK
                     MPEIQSAFYIPGIETKNNQKHKVKSVTTYLNSFTGKRYIDLFDFVEFLNTGRKQLSKY
                     EK"
     gene            20887..21969
                     /gene="gla"
                     /locus_tag="SPC38_0021"
     CDS             20887..21969
                     /gene="gla"
                     /locus_tag="SPC38_0021"
                     /note="member of homology group 96"
                     /codon_start=1
                     /transl_table=11
                     /product="putative epimerase"
                     /protein_id="CAI34414.1"
                     /db_xref="GOA:Q4JZ43"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR008089"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ43"
                     /translation="MKSKIILKNKTILVTGAAGFIGANLVMSLLQEENPLQIIGIDNL
                     NDYYDVSLKEYRLSTIQEECQSSLNKKWVFIKGDIADSDLMEEIFETYRPQIVVNLAA
                     QAGVRYSITNPDVYMKSNIIGFHTILEKCRKYQENIEHLVYASSSSVYGGNTKIPFSE
                     LDAVDNPVSLYAVTKKTNELEAHAYSKLYNIPTTGLRFFTVYGPAGRPDMAYFSFTKQ
                     LIDKKPIEIFNYGNCQRDFTYIDDIVEGVKRVMTGAPQKEIGEDGLPIPPYAIYNIGN
                     HQPENLLNFVEILQEKLIAASILPEDYDFSSAQKLVPMQAGDVVATYADISLLEKDFN
                     FKPKTSLRNGLRNFAEWYRNFYQRGE"
     misc_feature    20887..20976
                     /gene="gla"
                     /locus_tag="SPC38_0021"
                     /note="Signal peptide predicted for SPC1783 by SignalP 2.0
                     HMM (Signal peptide probability 0.974) with cleavage site
                     probability 0.471 between residues 30 and 31"
     misc_feature    20917..21948
                     /gene="gla"
                     /locus_tag="SPC38_0021"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00023"
     misc_feature    20920..21711
                     /gene="gla"
                     /locus_tag="SPC38_0021"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 8.3e-55"
     misc_feature    20920..21825
                     /gene="gla"
                     /locus_tag="SPC38_0021"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 7.1e-05"
     misc_feature    20923..21789
                     /gene="gla"
                     /locus_tag="SPC38_0021"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 5.4e-09"
     gene            21929..23197
                     /gene="ugd"
                     /locus_tag="SPC38_0022"
     CDS             21929..23197
                     /gene="ugd"
                     /locus_tag="SPC38_0022"
                     /note="member of homology group 20"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAI34415.1"
                     /db_xref="GOA:Q4JZ42"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ42"
                     /translation="MQNGIEIFIKGVNRMKITVVGMGYVGLSLAVLLAQHHEVTALDI
                     IDKKIQLINEKKSPIQDEYIEQYFLEKNLHLSATTNEVEAYKDAEMIIIAAPTDYDTH
                     KNFFDTSAVEQVIENIISMNNEALIVIKSTVPVGYTESIREKYGKKNILFSPEFLREA
                     NGLYDNLYPNRIIVGTDLNDGALVSKAHEFVSLLQEGALKENIDTLIMGFSEAEAVKL
                     FSNAYLALRVSYFNELDTYAELKGLNTKAIIDGVGLDPRIGQFYNNPSFGYGGYCLPK
                     DSKQLLSNYHDVPENIISAIVSSNETRKKFIAERILEIVGANHIDEYYNLKQEIVVGI
                     YRLVMKKGSDNFRHSSIQGIIKRLKANGVTLMIYEPSLPDGQLFFGSEVVHDFPKFKE
                     KSHLIVANRFDETLMDVKDKVYTRDLFGRD"
     misc_feature    21971..22369
                     /gene="ugd"
                     /locus_tag="SPC38_0022"
                     /note="HMMPfam hit to PF01210, NAD-dependent
                     glycerol-3-phosphate deh, score 0.0013"
     misc_feature    21971..22528
                     /gene="ugd"
                     /locus_tag="SPC38_0022"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.3e-45"
     misc_feature    22556..22837
                     /gene="ugd"
                     /locus_tag="SPC38_0022"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.6e-35"
     misc_feature    22937..23176
                     /gene="ugd"
                     /locus_tag="SPC38_0022"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 8.5e-05"
     gene            complement(23327..24576)
                     /gene="tnp"
                     /locus_tag="SPC38_0023"
                     /pseudo
     CDS             complement(join(23327..24061,24058..24576))
                     /gene="tnp"
                     /locus_tag="SPC38_0023"
                     /note="member of homology group 13"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
     misc_feature    complement(join(23834..24061,24058..24120))
                     /gene="tnp"
                     /locus_tag="SPC38_0023"
                     /note="HMMPfam hit to PF01610, Transposase, score 6e-23"
                     /pseudo
     gene            25509..26786
                     /gene="intron"
                     /locus_tag="SPC38_0024"
     CDS             25509..26786
                     /gene="intron"
                     /locus_tag="SPC38_0024"
                     /note="member of homology group 108"
                     /codon_start=1
                     /transl_table=11
                     /product="putative group II intron protein"
                     /protein_id="CAI34417.1"
                     /db_xref="GOA:Q4JZ41"
                     /db_xref="InterPro:IPR000477"
                     /db_xref="InterPro:IPR013597"
                     /db_xref="InterPro:IPR015706"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ41"
                     /translation="MSKLLDKILSRENMLEAYNQVKSDKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPGGGIRQLGIPTVMDRMIQQTIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQLYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     misc_feature    25683..26333
                     /gene="intron"
                     /locus_tag="SPC38_0024"
                     /note="HMMPfam hit to PF00078, Reverse transcriptase
                     (RNA-dependent DNA pol, score 1.1e-63"
     misc_feature    26379..26630
                     /gene="intron"
                     /locus_tag="SPC38_0024"
                     /note="HMMPfam hit to PF08388, Group II intron,
                     maturase-specific domain, score 3.5e-30"
     gene            complement(order(26843..27319,27321..27647))
                     /gene="tnp"
                     /locus_tag="SPC38_0025"
                     /pseudo
     CDS             complement(join(26843..27319,27321..27647))
                     /gene="tnp"
                     /locus_tag="SPC38_0025"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(27257..27319,27321..27629))
                     /gene="tnp"
                     /locus_tag="SPC38_0025"
                     /note="HMMPfam hit to PF01710, Transposase, score 2.2e-23"
                     /pseudo
     gene            order(27827..28225,28242..28736)
                     /gene="tnp"
                     /locus_tag="SPC38_0026"
                     /pseudo
     CDS             join(27827..28225,28242..28736)
                     /gene="tnp"
                     /locus_tag="SPC38_0026"
                     /note="member of homology group 19; member of homology
                     group 19"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
     misc_feature    join(28154..28225,28242..28616)
                     /gene="tnp"
                     /locus_tag="SPC38_0026"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 0.00054"
                     /pseudo
     gene            28879..29862
                     /gene="tnp"
                     /locus_tag="SPC38_0027"
                     /pseudo
     CDS             28879..29862
                     /gene="tnp"
                     /locus_tag="SPC38_0027"
                     /note="member of homology group 39"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1239 transposase"
     misc_feature    29386..29820
                     /gene="tnp"
                     /locus_tag="SPC38_0027"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 1.1e-18"
                     /pseudo
     gene            29939..>30298
                     /gene="aliA"
                     /locus_tag="SPC38_0028"
     CDS             29939..>30298
                     /gene="aliA"
                     /locus_tag="SPC38_0028"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34421.1"
                     /db_xref="GOA:Q4JZ40"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ40"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    29939..30031
                     /gene="aliA"
                     /locus_tag="SPC38_0028"
                     /note="Signal peptide predicted for SPC1791 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.782 between residues 31 and 32"
     misc_feature    30185..30253
                     /gene="aliA"
                     /locus_tag="SPC38_0028"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     9978 a   4747 c   5998 g   9575 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa cactgcggct aaagaagtac ttgaaaaaca
      121 ggtcttggct ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcatat aaaaacaagg gaggactgta taaaaagcag aaatcctttg
      241 ttttttataa ccaaggttta taaactttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gatgaacata aagaagcgtg tccttagtgc aggtctgact
      361 tttgcatctg ctttgctttt agctgcttgc ggccaatcag gttcagatac aaaaacttac
      421 tcatcaacct ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat
      481 aatacattga ttatcaccaa tctagttgat ggtttgcttg aaaatgacaa tcacggaaac
      541 ctagttccat ctttgccaga ggactggtct gtttcgagcg acggtctgac ttatacttac
      601 aaattgagaa aagatgccaa atggttcaca gctgacggtg aagagtactc cccagtcaag
      661 gcccaggatt ttgtgacagg tatcaagtac gtagtggata ataaatcaca ggctattgac
      721 ttgattcaaa actcgatcaa aggtttgaat gattatatta caggagcgga ttctgacttt
      781 tctaaggttg ggatgaaggc cattgacaac cagactgttg agtatacttt ggtacgccca
      841 gaaccttact ggaactcaaa aacaaccaac agtattcttt tcccggtaaa ctaagagttt
      901 ctaaattcaa aagggaaaga ttttgggacc ctatctccag atagtattct ctacagcggt
      961 ccttatttgt taaaagattt cacatcaaaa tcatttatcg agtatgtgaa aaacccacat
     1021 tactatgatc atgccaaagt atcgattgaa cacgtgaaat tggcttactt taatggatca
     1081 gatcaagaat tgactatccg taactttgaa agtggagctt attctatcgc tggagtttat
     1141 ccaaatagtt cgaactttgc taagaccaag gagaaatata aggataatat cgtctatagc
     1201 ttgcaggaca agacttcttg gtatttaaat ttcaatgtca atcgcgaggc ttgcaatcac
     1261 actactaaaa cgacagatga gcagaagaag tcaactgaga cagctgtctt gaacaaaaac
     1321 ttccgccaag cagtaaactt tgccttggac cgcacagccc attctgccca gtcaaatggg
     1381 gaagaggcgg ctagcaagac ccttcgtaac accttggtgc tcctacattt gtccaagttg
     1441 gagacaagac ctttggagaa gtagttgctt ctaaattggt caactatggt acagaatgga
     1501 ggtattgact tggcagatgc tcaggatgcc tatttcaaca aagaaaaagc ccaagcaaaa
     1561 tttgcggaag ctaaaaaaga attggcaagt caaggtgtga ctttccctat ttacgtgaat
     1621 gtggcagtag atcagacaag taaaaatgcc gttacaggca tgaactcagt taagcagact
     1681 ctggagtcag ttttaggtgc tgataacatt gttattgatg ttcagcaact ttcaacagat
     1741 gattttaata atgtaccttc ttggcaccga tgccagctga tagaggctat gatttgagct
     1801 ttgatggttg ggtgggtgac tatcaggatc catcaactta tctcaatcct ttcaatgcag
     1861 agaatggctt ctatctcaaa atttttggac cggatgccaa ggaagataag gaaaaaatca
     1921 ctagcctagg tcttgatacc tacactaaga tgctcaaaga tgcagatagt gaaaacaaag
     1981 atgtagccaa acgctatgaa aaatatgctg aagcacaggc ttggatgatt gacaattctc
     2041 tcattatgtc agctatgtca agtggtggca cagcatctgt aaccaaagtg atgccattta
     2101 caagagggca ttaattggtt ggtattaagg gtgatggcaa taactacaag tacatgaaac
     2161 tgcaaaaaga tactgtaaca accaaacggt ttgaaaaagc taagaccaaa tgggagcaag
     2221 aaagcaaaaa agcaatcgaa aaagcccaaa aagaagcaga aaaacatgtt aaatagttat
     2281 aaatagcttt ttcaaggaga attataaaga caaacatcag ttttggtgct tgtcttttta
     2341 aatcactcgg ttattgaaaa ttagacttct tgcgaaacag gctctttgtc aactgtagtg
     2401 ggttgaagaa aagctaagct cgagaaagga caaatttcgt cctttctttt ttgatgttca
     2461 aagtgataac aatccgtttt ttgaagtttt caaagtttcg aaaaccaaag gcattgcgct
     2521 tgataagttt gatgagatta ttggtcgctt ccaattttgc gttggaataa ggtaattgaa
     2581 gagcgttgac gattttttct ttgttcttta gaaaggtttt aaagacagtc tgaaaaatag
     2641 gatgaacctg cttaagattg tcctcaataa gtccgaaaaa tttctctggt tccttattct
     2701 ggaagtgaaa cagcaagagt tgatagagct gatagtgatg tttcaagtct tgtgaatagc
     2761 tcaaaagctt gtcaagaatt tctttatttg ttaagtgcat gcgaaaagta gggcgataaa
     2821 aacgtttatc gctcaattta cggctatcct gttgaatgag tttccagtag cgcttgatag
     2881 ccttgtattc atgggatttt cgatgaaact gattcatgat ttggacacgc acacgactca
     2941 tagcacggct aagatgttgt acaatgtgaa agcgatcaag aacgatttta gcattcggga
     3001 gtgaaacagc ctgggagact gtttcagcct gagcctagaa atttgaaagc gaagctgttt
     3061 agccaagtca tagtaagggc taaacatatc catagtaatg attttgacgc gacatcggac
     3121 ggctctatca tatttaagaa agtgatctcg gatgacagct tgtgttctgc cttcaagaac
     3181 agtgataata ttaagattat caaaatcttg cgcaatgaag ctcatctcca tctcccgatt
     3241 gaaacagtca ctccccggac tgtttcaacc tcccaagaca taatctcagg cagatttcta
     3301 aaattacact caaagtggaa gtcattgagc ttgcgaatga cagttgaagt tgaaatggcc
     3361 agctgatggg caatatcagt catagaaatt ttttcaatta acttttgagc aattttttgg
     3421 ttgatgatac gagggatttg gtgatttttc tttaccaggg gagtctcagc aaccatcatt
     3481 tttgaacagt gatagcactt gaaacggcgt tttctaagga gaattctaga aggcatacca
     3541 gttgtttcga ggtaagggat cttagacggt ttttgaaagt catatttctt cattagactt
     3601 ccacaatcag ggcaagatgg agcctcataa tccagcttag cgataatttc tttgtgggta
     3661 tccatattga tgatatctag aatcttgatg tttgggtctt taatatcgag cagttttgtg
     3721 ataaaatgta attgttccat atgaatcttt ctaatgagtt gttttgtcgc ttttcattat
     3781 aggtcatatg ggactttttt tctacaacaa aataggctcc ataatatcta taggggattt
     3841 acccactaca aatattatag agccgcgaaa caaatatggt ataatagttc tatggattat
     3901 gaagcaagta aacaactaac tgatgcacga tttaagcgtc ttgttggtgt tcagcgtacc
     3961 acttttgaag agatgttagc tgtattaaaa acagcttatc aacttaaaca cgcaaaaggt
     4021 ggacgaaaac ctaaattaag cctagaagac cttcttatgg ccactcttca atatgtgcga
     4081 gaatatcgca cttatgaaca aattgcggcc gattttggta ttcacgaaag caacttaatc
     4141 cgtcggagcc aatgggttga agtaactctt gttcaaagtg gttttacgat ttcaagaact
     4201 cctctcagtt ctgaggacac ggtaatgatt gatgcgacgg aagtaaaaat caatcgccct
     4261 aaaaaaagaa ttagccccaa atttcaagtt gaagttagcc acccaaaaga aattcacttg
     4321 gcgacttgta gtccaagcat tttttagggt agttgttaat ccaattttcg ataaaagcta
     4381 cttctttcgg agtcgttttc ttggttcctt taggtaacca tctccgaatt aatcgattat
     4441 gattttcatt tgaacctctc tcccatgaag agtaagcatg tgcgtagtag atatgttcct
     4501 caggaaatac ctcagacaat cgtttgaact ccgaaccatt atctgcagta atggacagaa
     4561 tacgatgctc ccctaatagt aacgtaagcg cctgattgac agattcagca gttttatttg
     4621 gaattaacct tataatttgg tgtctgctcc gccggtcggt taagactaac aggcaataat
     4681 tttttatctt agtcagtagg acggtatcaa tttcataatg accattttcc aagcgaagat
     4741 taataacgtc aggacgttct tcgatagatt tacctgccgg cttaaagttc ggactagctt
     4801 gcttcttgac acctttcctt tttctgggat aaagcatgtc ggccttcgtc aatcctaaat
     4861 gaccattatg aaaccagtag tagatggttg aaataccaac tttcacttgc ttcttgttaa
     4921 ccatcatttc aggcgaaaat ttttgcttat gatagtgtaa gatcttctct ctgatttcct
     4981 ttgttaaaat taactttttc accgaccgtt ttcgattgaa ttggtaaaca gtttgtgcgt
     5041 aatcggcaga atagaccttt ttgtatagcc cttttctcac ttgttgtaaa gttgtacctc
     5101 ttttgacttc attatgaatc gtttgaggcg cctttcctaa caagcctgca atttcacgat
     5161 tggacttatt ttcattcttc caccgctcaa tcaagcgacg gttatctatt gtcaaatgtt
     5221 tcccttttgg ggtataatgt tcttgcatct ctgtgccttt ccttgtgttt gtggttgaac
     5281 aacaagtata gcacagaggt gttttcttat accttaaatc acatttcatt tgacaacagg
     5341 aacccttgaa cctgtttttt cagctaaacc aaggctatga ttagccttgg ccacctagcc
     5401 taacagtttc aaacctgtta tcaaatgaaa tcatcaactt actcaaacat agtgaaacat
     5461 ctaattcttg actaaggtaa ggtggctaac ttcattatag aactttcaaa aaaagaatta
     5521 gcaaattatt ctggtaaaaa gaaatgccgc gctatggaaa aatgatttgt tttgtgctaa
     5581 aatagattga aactaatact caatgaaaat caaagagtaa cttggaagtt agctcaaagt
     5641 acagctttaa ggtggtagat agaactgacg aagtcagctc aaaatactgt tttgaggttg
     5701 cagatggacg ctgacgtggt ttgaagagat tttcgaagag tataagatcc tctcttttgc
     5761 tatagttaag gagatgagag gtaaatgata agggagagac tatgtacgac tatctaatcg
     5821 ttggtgctgg tttgtcggga gcaatttttg cttatgaagc aaccaagcgt ggaaaaaaag
     5881 taaaagttat tgataaacgt aaccacattg gtggaaatat ctactgtgag aatatagaag
     5941 gagttaatgt tcataaatat ggtgcacata tcttccatac ttctaataag aaagtctggg
     6001 attatgtgaa tcaatttgct gaatttaaca actacatcaa ctcgcctgta gctaattaca
     6061 agggtagcct ttataatcta cctttcaata tgaatacttt ctatgctatg tgggggacaa
     6121 aaactcctca agaagtgaaa aataagattg ctgagcaaac ggctcacatg aaagacgttg
     6181 aaccgaaaaa cttggaagaa caggctatca agttgatcgg tccagatatt tatgaaaagt
     6241 tgattaaagg atatactgaa aagcaatggg gacgttccgc gactgacctt ccaccgttta
     6301 tcatcaaacg tctaccagtt cgtttgactt ttgataataa ctactttaat gaccgttacc
     6361 aaggtattcc aatcggtggc tataatgtca ttatcgaaaa tatgctgaaa gatgttgaag
     6421 tagaacttgg agttgacttt tttgccaatc gtcaggaatt agaagcttct gctgaaaaag
     6481 ttgtctttac agggatgatt gaccaatatt tcgattataa acatggtgag ctagaatacc
     6541 gtagtcttcg ttttgagcat gaagttctag ataaggaaaa ttatcaagga aatgccgttg
     6601 ttaattatac agaacgagaa attccttata ctcgcattat tgagcacaaa cattttgagt
     6661 acggaacaca agataaaacg gttattactc gtgaataccc agctgattgg aaacgtggag
     6721 atgaacctta ttatccaatc aatgatgaga gaaacaatgc catgtttgct aaatatcaag
     6781 aagaagcagt acagaatgat aaggtaattt tctgtggacg tttggctgat tataaatact
     6841 acgacatgca tgtggttatt gaacgggctt tggaagtggt aaggaatgag ttctcatgag
     6901 agaaacaggc atatatgaaa gttaatgtag aggagttgag ctttttattt gaatattggg
     6961 tgaaaaagta gtatacttag atagtctgtt tttaaaaatc aaaatgggga aatcgattct
     7021 tatcaacttc agagtgaact gaattaaaac tgcataggag tatataaaat gctgaagtaa
     7081 gatttacaga acatggtatg ataagtgttc gacagcttgt ttggcaggag ttcgaatatt
     7141 caagtaattg agagggtttt tgaacttctg ataagataga tagtagatta ctttcgagta
     7201 aaggatagtt gagaaaatga ataatcgtat agtagacatc agtttgtttg atttattgaa
     7261 tgtcttatgg cttcgtaaat ggatcattgt ttttgtatca tttgtttttg gatgtatttc
     7321 ttttttatat tatcaatttt ttgtacccaa aacctataca agtgatactc gtatatatgt
     7381 ggtaagcaaa ggggataata aaaatctgtc taatgcagat ttgcaagcag gaagtgctct
     7441 aacaaaggat tacaaagaaa tcattttatc agatgaagtg ttagaagaaa caatttctga
     7501 tttaaaacta gaatcaactt tggaatctct agcttcgaaa attaaaattt ctatccctgc
     7561 ggaaactcga attatttcca ttagtgttac aaatacgaac tcagatgaag ctgctcgaat
     7621 agcaaatggg ataaggaagg tagctgccct taaaatcaag gaagtaactc aagttacaga
     7681 tgtcaccact ttacagactg cacgccctcc ccaaactccg tcaggaccgc atgtgcgaaa
     7741 atctactaca gcagggcttg ttcttggtgc attcttaaca gtctttctag tagttgccaa
     7801 ggaaatatta gatgatcgca taaaacgttt tgaagaactt gaaaaattgg gaatccctat
     7861 tttaggctca atccctttat caaaaaatat aaagtagaaa atcatgggaa aattagaact
     7921 aacacgtaag tactatcaat tgtacaatga aacgaaagaa tattttaatg ccttacagac
     7981 caatattcaa cttagtggtg atggactgaa agtcatttct gttacttcca cagtaaaaaa
     8041 cgaaggcaaa tcgactatat cagttggctt gtccatgtcc ttggccttat caggctataa
     8101 agtcctgtta ctggatgtgg atttacgtaa ttcagtgatg tcaggaatgt ttcattctag
     8161 ggaaagaata acaggtttga ctgaatattt atctggcaaa gcgggaatgg cggattctat
     8221 gcaggaaact actttagata atctctatat attacaagca ggagtcgttt caccgaatcc
     8281 cttatctcta ttaaggagtg ttaagtttga aaccttgata gattctatga aaaagtactt
     8341 tgactatatt atagtagata ctccaccaat cggccaagta atagatgctg caattattgc
     8401 ccaacaatgt gatgggatat ttttggtcac tgaaatgagg aaaacgacac gcagacaaat
     8461 tttttcttcc ctccagcaat tggaacaaac tggagttccc gttttgggcc ttgtggccaa
     8521 taaagcaatt ataaaaaaag atagctatgg ctattatgga aaaaacaccg cgagcgagac
     8581 tgaaagatat tgatggacta cctcctctac ctcacaaatt gcattttttg tgaggtagag
     8641 gggtaagttg atactattat atattagact tcctgcgaaa caaaatatgg tatagtagtt
     8701 ctatgaatga tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt cttgttggtg
     8761 ttcagcgtac cacttttgaa gagatgttag ctgtattaaa aacagcttat caacttaaac
     8821 acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ccttcttatg gctactcttc
     8881 aatatgtgcg agaatatcga acttatgaag aaattacggc tgattttggt attcacgaaa
     8941 gcaacttact ccgtcggagc caatgggttg aagtaactct tgttcaaagt ggtgttacga
     9001 tttcaagaac tcctctcagc tctgaggaca cggtaatgat tgatgcgacg gaagtacaaa
     9061 tcaaccgccc taaaaaaaga attagcgaat gattctggta aaaagaaatg ccacgctatg
     9121 aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat cgctgtgaac
     9181 tatttgttat gatatgaagt tgttcaaaat gagtcgcaga aatatcggac aagctggtaa
     9241 aatcttggct gacagtggtt atcaagggct catgaagata tatcctcaag cacaaactcc
     9301 acgtaaatcc agcaaactca agccgctaac agctgaagat aaagcctgta accatgcgct
     9361 atccaaggag agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt
     9421 ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgc
     9481 tattatcaat catgaactag gattctagtt tggcaggaag tctattttgg aatgctatta
     9541 tgtttagttg tgctcaatga aaatgaaaga actagtaagc taggcgcagt cagctcaaaa
     9601 cagtgttttg aggttgtaga tagaactgac gaagtcagta acatatatat gacaaaccga
     9661 tgctgacgtg gtttgaagag atttttgaag agtataagac ggtattttaa gggaatgatt
     9721 actatttgag gtattttatg agtagagaga aaaaaagagg aacagcagtc cacttgaaat
     9781 cttatatcaa tagtgtgctg ctaatcctgt acacaggaat agcgagccta tttctttttc
     9841 agatattccg atacaatatt ttaaatttta ggaatctcaa tttattagta gctctgctag
     9901 tagtattggt atttatttta ggagtgagtt tgattgtccg aaaaaaagct gaaaagttga
     9961 caatgcttct cctaatctta gctgtcgcaa gtagttcaat atcgcttttg gctgttcaac
    10021 aatttatcgg ttttacaagt cgcttaaatg caacttcaaa cgtttcagaa tatgctatta
    10081 gtcttgtagt tttgaaagat agcgaaatta gtgaactaga acaagtatca catgtgatgg
    10141 cgcctaccga tacagattat gaagctattc aaagtttgtt agcagatata aaagaaaagc
    10201 aaggtaaaga tctaatagta gataaaagca aatcttattt agaagcctat aagagtttga
    10261 tttcaggtga caccaaggtg atttttttaa atagtatttt tgaacatatg attgagtcgg
    10321 attttcctga ctttagagac aaaattaaga aaatatatac aaaagaaatg acaaagaaag
    10381 tagaagctcc aaaggtttca aaggggcaga cttttactat ttatttcagt gggattgata
    10441 cttatggacc aattaactct gtatcacgtt cggatgtcaa tattttgatg acagtcaata
    10501 gcgagaccaa aaaaattctt ttgacaacta cacctcgtga ctcctatgtc gcaattgcag
    10561 atggaggaaa gaatcaaaaa gataaattga ctcatgctgg aatttatggt attgattctt
    10621 ccattcatac cttggaacat ttatatggtg tagagattaa ctactatgtt cgtgtaaatt
    10681 tcacttcttt cttaaagata gttgatttat tgaatggtat tgatgtggac aatagtcaag
    10741 aatttacaat tgacgggaac gactatcctg ttggaaatct ccatctaaat tctaagtcag
    10801 cacttggttt cgttcgagaa cgtcattctc tagcagatgg agatcgtgat cgaggacgga
    10861 atcaacagaa ggtgctcgct gcaattattc aaaaattaac ctcaatagaa tcattgaaaa
    10921 attatcgtca aatcatgcaa ggattagagg attcaataca aacaaatctc tctccaacaa
    10981 ctatcatgga cttagccaat actcaattgg aaagtggagg gaattataaa ataaattctc
    11041 aagatttaaa agggacaggg cggatggatc ttccttctta tgcaatgcct gatagtcagt
    11101 tgtatatgat ggaaattgat gagaatagcc tctcagctat caaagaaaat attcaggctg
    11161 ttctggaggg taggtaagat gatagatgtt cattctcaca ttatttttga tgtggatgat
    11221 gggccaaagt ccatagaaga tagtagagct ttgttgttag aagcctatga tcaaggaatt
    11281 cggacaattg tttcaacatc ccaccgccgt caaggtatgt ttgaaacacc agaagacaag
    11341 attgcggaaa attttcgtgc ggtacagaaa atagctagag atattgcaga tgatttaaca
    11401 attttatatg gtgcagaaat ctactatact caagacatta tcaataaact tgaaaagaaa
    11461 actttcccaa ctttaaatgg gagtcgatat gccttgattg aatttagtag cgagacttct
    11521 tatcgttcta ttcatagcgc tcttcagcag ttgcttttgt caggaattac cccgcttatc
    11581 gcccatatcg aacgttatga tgctcttgaa aacaataaac aagcagttct cgaattgatt
    11641 cgtatgggct gttatacaca gattaatagt tcccatctac tcaaaaaaaa attatttaaa
    11701 gatgatgcaa aaatcatgaa gaaacgagtt cactattttt tgaaacatga tttagtccat
    11761 attgtagcaa gtgacatgca taatcttgat actagaccgc cttatatggc ggaagcttat
    11821 gaaatcattt ctaaaagata cggaaaagaa aaagctgaag aattttttat aaaaaatccg
    11881 caacgaatcc taatggatca attgatttaa tgaaaaagga aacaacaaat gtataaagtt
    11941 atcaaacgat ttatagatat agctttagct ttgctaggaa ttgtattatt atcaccacta
    12001 tttttaggaa ttatagtgtt cataaaatta gaatctaaag ggactatttt ctttaaacaa
    12061 aaaagaattg ggctacataa aaaagaattt tacattctaa aatttagaac gatgagaatt
    12121 gacactcctt cagctgtccc tacacatctt ttaaaaaatc cttatcaatg gattacaaag
    12181 gttggtaaag tcttacgtag aacctctctg gatgaattgc cacagatttg gaatattttg
    12241 gtcggtcaca tgtcgcttgt aggaccaaga cctgcccttt ggaatcaatt tgatttgatt
    12301 gaagaaagag acaaatatgg agcaaatgat attttacctg gtttaacagg ttgggcacaa
    12361 atcaatggaa gagatgaatt atctattcca gtcaaagcca aatttgatgg ctactatgtg
    12421 aagaactgtt catttgtttt agattgtcga tgtgttgtag aaagtttttt agtagtattt
    12481 aagagatatg ggcatcgaga aggtggtgca gattagagga actgatatat gggaaatcgt
    12541 aaaaaagttt ttgtagtagc caatgtagtc aaagaacata ttctaaaatt tcacattccg
    12601 actatcaaag aaatgacaaa aagagggtgg acggtagacg taggtgcttc tggggatgaa
    12661 acagttccct attgtcacca acaatattca ctgccccacc aacgttctcc gtttcatcta
    12721 ggcactctca aaagtatctg gaaattgaga aaaattttga agtctggagg ctatgatatt
    12781 gtttactgtc atactcctgt tggaggtttg gtgggacgac tggcttcttt aggattgcga
    12841 aaacaaggaa caagagtcat ttattttgtt catggatatc atttttacaa aggagcaact
    12901 tttttcaatt ggttagtgta ttacccaatt gaaaagctac tgtccctttt tacagatagt
    12961 atcattctaa tcaatcaaga agattatcat ctcacaaaaa caaaatttaa acaggttcaa
    13021 tcctatctag tgagtggaat gggagtaaaa caagaacggt tttcacccca atcaaatcaa
    13081 gttagagaac gttatcgtaa agaattgaaa ctgcctgagg atgcgactgt tttaatttat
    13141 tgtgctgagc taataaaaaa taaaaatcaa acatttttac ttcatgctat gaaaaagctt
    13201 gtggatcagg gagaaaatct ttattgctta ttagtaggaa ttgattatac caagggtgaa
    13261 atggtagaat atattcaatc cttgaattta tccgatcgag ttttactttt agggtggaga
    13321 gaagatattg ccaatcttta cgcttgttct gatatatgtg ttgcaacaag tattcgagaa
    13381 ggatttggat taaatatagt ggaagcaatg ttttgtcacg ttccagttgt tgcgaccatc
    13441 aatagaggac acgccagtat tatacaagat ggacaaaacg gtctattagt ccaattagga
    13501 aatacaaagc aattagtaga ggctatttat gtactaatga aggatactaa gaagaagcaa
    13561 gaattagtgg agcaagctag tgcgaattta gaacaatatc atagtcagaa aattgtaaat
    13621 agcttactag aaataataga acagactgca atgaagtgag tgaaggatgt gaaaaagtga
    13681 aaatacaaat tgataaaata tactatctat ttttttggct ggtagtttcc tttggatatt
    13741 tttttatgat gccaaccttt acagaagatt tagaaggcgt tgtcagtgct agtttagtac
    13801 aattgttatt atttattata ggatatgtat atgtatctta tttaaatcgt tcttttatct
    13861 cactgtatag tatctttatg attgtatttt acctttttca aaatggacag gtattgttat
    13921 attcacttgg agtagagtat gattactttt atgttttaag atatgatgaa accatcgtac
    13981 tacaatcagt tattttttca acacaatgtc ttattgcagc ctttatggct ggagtctttt
    14041 ctacgaagaa agaggtatca aaaccccttt attcttatat ggatcaatta gaacgagaaa
    14101 aactgattac tactggaaag ttattttggg gtgcgtttgc gatttttgct ttacccttta
    14161 tgatgatgaa gcttgttatc accagtacat ctgggtattt tgcgatgata cgtttcgttg
    14221 gaagcctacc tacaataaca gtgttatttg aaaaaatgtt cattgcttca agtgtttttt
    14281 tgattgttta tttaaaatct gaggaaactt ggagcaagtt tttaaaagtt gttatcttag
    14341 gttggagtat aatggctgct ttaacaggag atagaaccgt aggtttagca gggattgtta
    14401 cgttagcttt aattcaaaca ttaattggta atcgtaaaaa aaagattaag ttttctcagt
    14461 atgccttgtt agttggggca gctgttgtag tgatgtattt aatgtccttt gcttttcaat
    14521 ttaggatgca acaagattct aaagtttcag gactacaaac tgcggtagta gaaatgatag
    14581 gaactctagg gtttagtttt ttcccactcg tattaacgat tagaattgtt ccaacttcta
    14641 ttaacttttt tagaggaaaa tcatatattg cagccatcat tacaggacta attccatcta
    14701 attttgattt tttacattta acaaatacat tatcagaatg gaatgcatat ccaacggaat
    14761 tattagatac aatctatcat tatggtttcg gattagatta ttctttaatt gcggaagcct
    14821 atattaattt tggttcttat ggatggatag cgattttttt cctttgttct ctaatagctt
    14881 attttgtaag agatgtggat tttaaaagaa aggacaactt attctcacaa tatgctagct
    14941 tgattttgct gtattcatgg tttacccttc caagaagaaa atcttatttt atttttaata
    15001 attttttttg gtatgtatta ttttttggac tagcactcat acttgtctct cgttctatta
    15061 aacaacgaaa ggaatttaaa aaatgaaaat ttcaattatt atgggcattc ataatggtga
    15121 aaagcgcttt gaaacagctg ttcaaagtat tttcaatcaa acttatgata attgggaatt
    15181 tattatttgt gatgatgctt ccacagataa aacgtttgaa aagttacaag gattatatgg
    15241 acaggattca cgttttatct tattaaaaaa tgaaaaaaat gtaggtcttt ccgcgacatt
    15301 aaaccgttgc attgaagcaa gtagtggaga atttattgct agaatggatg atgatgatat
    15361 ttgttatccc gagcgctttg aaagacaagt cgactatttg ttccatcatc cagagattga
    15421 ttttgtttct tcatctattg atatttttga tggagaagta gttgtaggta cacggatttt
    15481 acttgatttt cctagtaaaa aggatttgat ttggaatagc ccctttgttc atcctgttac
    15541 catgtttcgt agagatgcct tgcttgaagt tggcggttat agagtttctc cagaaactgt
    15601 tcgtgggcaa gattatgatt tgtttatgcg actatattca tgcgagaaaa aaggtggaaa
    15661 tattttagaa ccactatttc gctatacgat tgatcaaaat acgatgaagc gacgtacgtt
    15721 taaagctcga attggggaaa tgattattcg ctataaaggt tatcgtgcga tgaaagttcc
    15781 attttataat tatgttttta tatttaaacc attagtagct catctagtaa cactcgttaa
    15841 aaggagataa tgtttatgaa aattttaata accactcata cttatcttcc taataaagat
    15901 ggtgttcaat ttgttaatca atatttagca gaaggattgg ttaaaagagg acatcaagta
    15961 acggtgctga cctattgtta tccatcacgt acaagggtac ctagagaagt gataaatggt
    16021 gttagagtca ttcgttggaa tgctcgaaca agctgtactt tccataaagg agaaaaatta
    16081 gcttatcaaa acttcatctt aaactcccaa tcagattatg atgttttagt gaatgttgga
    16141 acacagactg ctttaacaga ttggttattt ccgatatttt ctcagctaac aattccgaaa
    16201 gtcttatata ttcattcgat atgggatttc aactggttgc attggcatag acaatcattc
    16261 aagcgatttg ttgctaaagc ttgggcaaat gtacgatgga aatattatta ttggacaaag
    16321 gcttctatct ttaagcaata tcatgaagtg attcagctgc acccaaaaga ttatagtgtg
    16381 gcttttttta aagaaaaata tggcatagaa agtcagattt tagaaaatgc tgctgatgct
    16441 tctttttttc aaaatagaaa tgctgtcaaa aagcaatctt acattgtaaa tgtttctaat
    16501 tttaatgatc gaaaaaatca gaagaaagcg gttgagtatt ttttgaaaag caatcttcca
    16561 aatgaatgga agctcgtttt agttggttca gaaaagaatc agtatttaca aagtctacaa
    16621 acttttgaaa aagaactccg aaaccaatta ggtatcactt caggtaaaga aatagaatat
    16681 cgcatcggac tgtcaagaga agaagtcgta aaaactgtaa aagaagcttc tttttgttta
    16741 atgacaagta tatgggaagc ttttccaatt tccttaattg aagtgatggc tgcaggaatt
    16801 ccatttatct cttctgatgt aggaattgtc aactatttgt ctggaggaat cactgcttgt
    16861 agtgatcaag aatttataag agctattgaa gagtttgcca gttgtccaga aattagaaat
    16921 caatatggca aaaagggaca aatggaagca aaagaacatt atcaagtgga tgataaagta
    16981 aaagagcttg aagctttgtt acaaaaggtc gtaaaggaag aaaaagagtg aaaaaaatag
    17041 tatttttgtg tccatacttt gggactttac caccccatac gcagttatgg ctaaattctt
    17101 gtaaaatgaa tccgtctgtg acatggtatc tttttacaga tgacaagaga aaatttgact
    17161 atccagaaaa tgtgcaagta ttttatacga ctttggaaga aacaaaggcg ttgtatcaaa
    17221 agaaatttga ttttgagatt tctttagagg gggcttataa actcggagat tataaacctt
    17281 tatttggtta tctttatgag gaaatgatac aagagtttga tgcttgggga catattgatg
    17341 tttatgatga aatctatgga gatattcgtg catttgtaac agatgaatta ctagaaaaat
    17401 acgataaatt gatgattttt gggcatatgg ggatttataa aaattctccc gaagtcaatc
    17461 gtagatttga attgtcgtct gatttgaatc gtacttatca agaaatattt tcttcatcac
    17521 aattttataa ttttgaagaa tatgttgcag gaagtattac tcgtatctat cagaaaaatg
    17581 gattccccat tggaaaatta gatgaggtga ttgcggatct ttctggtaca agttatcatt
    17641 ttcgacgagg gtacatttca gatgattttg aaacatttac ttatttacca tatgagccta
    17701 tgattttttc atgggaagag gggaaaacgt attgttattc ggttaagaat catcaagtgc
    17761 aaaaagatga gtttatgtat gttcacttta agcgtcgaaa aatgattcaa gatataccag
    17821 atgatgcttc tacttattta atcgtcccaa gtggttttgc cttgatgcct gaagagataa
    17881 cggttgattt gattcgaaaa tatagtcaga aaaaattatt ttatccagtt tattttgaag
    17941 aaaagtggaa aggtttcaaa cgattatgga ataaaatttg gaggtcggaa tgaagaacat
    18001 tttaaaaaaa ttgatacaac aattaccgga taaactgttt ctacaaatta agtatttcta
    18061 catttttaag aagaaattaa atttaaaaaa tcctaagacc ttcaatgaaa aattacaatg
    18121 gctaaaatta tatgatagaa atccttttta taccatttta gcggataaga ttttagtgaa
    18181 ggactatatt gccaagacac ttggggaaga atatgttatt ccgactcttg gtgtttatca
    18241 tcattttgat gagattgatt ttgatgagct tccaaattct tttgtgatga aaaccaatca
    18301 tgatagtggc agtattatca ttgtaaaaaa caaagaagac ttgaatattc aagaagcaag
    18361 agaaaagcta caaaaaagtt tggaaagaga ttattttatt tttggtcgtg aatggcctta
    18421 taaaaatatt gaacgaaaaa ttattattga agagtttatg acggatgaat cgaatcaaga
    18481 attaaaggat tataaaattt attgttttaa tggtcttcct aagtttgttc atgtagatta
    18541 tgaccgtttt acaaatcata agagaaatat ttatgatagc aactggaagc agcaagaatt
    18601 tatgtatgct tttccgtccg ataaaaataa gacgatagag aagcctgctg aactgtctga
    18661 aatgattgaa cttgtgagaa aattatcaaa agagatgcca tttgtgagat gtgattttta
    18721 tatcgtcaat cacaaaattt tgtttggtga gatgactttt tgtccaggtt cagggtttga
    18781 aaaattttat ccagaacagt atgatgtaga gtttggaaag gatattactt taccggagaa
    18841 gcatgaatgg aaacaaaaga aaaacgttta gttcataata cgattatttt tacaattgga
    18901 agtttaggtt caaaatttat tcagtttttg ttagttcctt tgtataccta tactttaaca
    18961 gcttctcagt ttgggattac cgaaatttta ttaaccgctg ttaatctttt aatacctgta
    19021 ttttctattt ccattgctga tggattatta agatttggat tagataagac cttaagaaga
    19081 gaaaatgtct tgaaatcagc ttttatcatt tcgatacttg ggactatttt atccattatt
    19141 tcgattccaa ttttttcgct ctatcctact ttgtcagagt ggatggttta ttttatcatc
    19201 attttgaact tgagaatgta tcgggatgtt tttgcgattc aattgaaagt tgaagggaaa
    19261 aatacattat ttgcttgcga tagtatgatt tatacatttg ttttatcttt agcgagtatt
    19321 gtctttctag ttcctttttc tttaggcatt tcaggttatt ttttcgctta tattgtcagt
    19381 aatggaattt ccattttctt tatcttattt ttcggaggag tctggaaaag ttttactagc
    19441 ggaagatttg aaaaacaatt gatgatacaa ctattgaaat attcagcacc catgatttta
    19501 aatggtattg catggtggat tacaaatgcc tcagatcggt ttatgttgca atggtttatg
    19561 gatgatagag cggtaggttt gtatggtgtt gttgcaaagt tacccttatt aatcggaacg
    19621 tttactggag tatttaatca ggcatggatt atttcagcag tagaagagtt tgaagaagaa
    19681 aatgaagaat ggttttatca aaaagttttt caccaatatt atgcagcact ctttttaagt
    19741 gtttcagtat ttttgcttct acttcaacca tttatgaaag tatatgttag tccaagcttt
    19801 tatgaagcat ggcaatatgc tccgttttta ttattgtcaa gtgtagtttc aggaatcgcc
    19861 gcatttatga caggttttta tgttgcgcaa aagaaaaatt tgaatattat atacacgacg
    19921 attgctggtg cttttgcgaa tattttgtta aatgcgatgt ttattcctat gcttggagta
    19981 ttaggcgctt ccattgcgac ctttctatca tggtttgtta ttgcaatcta tcgtatgaaa
    20041 gatgttgaaa actttgcttg ttttccatta gataaaaaag ttttttggta tttatttcta
    20101 ttatgtattc agaccattac gatgactttt ctgccaatcc ttggcattgt tttttcagtc
    20161 gtattgattc cttatttctt ttaccaagaa caggaatttc tagcagtttt atttgataaa
    20221 ggaaggaaaa aagtatgttc attcaaaaaa tcaaaaagat aataagagta tttttaagga
    20281 aatctttagt aaaagattat cgacaaagaa ttcaaaataa agagtttact cttattactt
    20341 ctaattgtgt gggtggactg attagtcatg atttgggtct acaatttcgt tctcccacta
    20401 tcaatatgta tatagaagca gcagacttta ttcagttttg ttcacattta gaacgctatt
    20461 taaaagaaga cttatctttt attgaagtaa atcaagatgg acattttgta gctctttgtg
    20521 gggatataaa aatttatatt gttcattata atagctttga agagtttgct aaaaaatggt
    20581 ctgaacgtgc caaaagagta gattttgatc aattatatct tatgatgtct gaacgagatg
    20641 gctgtcgtta tgaagatatt gtgaagtttg atacgttacc ctataagaat aaagtaattt
    20701 ttacaagtaa aaagatgcca gaaattcaat ccgcttttta tataccaggt attgaaacaa
    20761 aaaataatca aaaacataag gtgaaatcag taacaactta tcttaactcc tttacaggaa
    20821 aacgatatat agatttattc gactttgtag agtttttgaa tacaggaagg aaacaattaa
    20881 gtaagtatga aaagtaagat aatattaaaa aataaaacaa ttcttgttac aggagcagct
    20941 ggctttattg gtgctaatct tgtcatgagt ttattacaag aagaaaatcc attacagatt
    21001 attggaatag ataatttgaa tgattattat gatgtttctt taaaagagta tcgtttatca
    21061 acaattcaag aggagtgtca atcatcttta aataaaaaat gggtatttat caaaggagat
    21121 attgctgatt ctgatttgat ggaagaaatt tttgagacgt atagacctca aattgtagtg
    21181 aatttggcag cacaagcagg tgttcgttat tctatcacta atcctgatgt ttatatgaaa
    21241 agtaatatca ttggatttca tactattctt gaaaaatgta gaaagtatca agaaaatatt
    21301 gaacatttag tttatgcatc atcctcttct gtttatggtg gaaatacaaa aattcctttt
    21361 tctgaattag atgcagtaga caatcctgtt tctttatatg cagttacgaa gaaaacaaat
    21421 gaattagaag cacatgcgta ttcaaaattg tacaatattc caacaacagg cctgagattt
    21481 tttacagttt atggaccagc tggaagacct gatatggctt attttagttt tacaaagcaa
    21541 ttaattgata aaaagccaat tgaaattttc aattatggga attgtcaacg tgattttact
    21601 tatattgacg atattgttga aggcgttaaa agagtgatga ctggagctcc tcaaaaagaa
    21661 attggagaag atgggttacc aattcctcct tatgctatct ataatattgg aaatcaccaa
    21721 ccagaaaatt tattgaattt tgtcgaaatc ttgcaagaaa aattgatagc tgcttctatt
    21781 ttaccagaag attatgattt ctcatctgct cagaaacttg ttccaatgca agctggtgat
    21841 gtagttgcaa cctatgcaga tataagtcta ttggagaagg attttaattt caaacctaag
    21901 actagtctta gaaatggctt gagaaatttt gcagaatggt atagaaattt ttatcaaagg
    21961 ggtgaataga atgaaaatta ctgtagtagg aatgggatat gtcggattgt ccttggcggt
    22021 attattagcg caacatcatg aagtaacagc gttagatatt attgataaaa aaattcaact
    22081 catcaatgag aaaaaatctc caattcaaga tgagtatatt gaacaatact ttttagaaaa
    22141 aaatcttcat ttaagcgcaa caacaaacga agtagaggcg tataaagatg cggaaatgat
    22201 tattatagct gctcctacag attatgatac acacaaaaat ttctttgata catctgccgt
    22261 agaacaagta atcgaaaata ttatttctat gaataacgag gctttaattg tcattaaatc
    22321 aactgttcct gttggctata cggagtcgat tcgagaaaaa tatggtaaaa agaatatact
    22381 gtttagccca gaatttcttc gtgaagcaaa tggattgtat gataatcttt atcctaatcg
    22441 aattatcgta ggtacagatt tgaatgatgg agcattagtt tctaaagcac atgaatttgt
    22501 gtctttacta caagaaggtg ctctcaaaga gaatattgat actttaatca tgggattttc
    22561 tgaagcagaa gctgtgaaat tattttccaa tgcttatctg gctttaagag tgtcttattt
    22621 taatgagttg gatacttatg ctgaactgaa aggattgaat acgaaagcca ttattgatgg
    22681 agtaggattg gatcctagaa ttggtcagtt ttataacaat ccatcctttg gttatggtgg
    22741 ttactgttta ccaaaggata gtaagcaact gttgtcaaat tatcatgatg ttcctgaaaa
    22801 tattatttca gcaattgttt ctagtaatga aactcgtaaa aaatttattg cagaacgtat
    22861 tcttgaaata gtcggagcta atcatattga tgaatactat aatttgaagc aggaaatcgt
    22921 tgtaggtatt tatcgtttag tcatgaaaaa aggttcggat aattttagac attcttctat
    22981 ccaaggaatt ataaagagac taaaagcgaa tggagtgaca ttaatgatct atgaaccttc
    23041 acttccagat ggacaattat tttttggaag tgaagttgtt catgattttc caaaatttaa
    23101 agaaaaaagc caccttattg tagccaatcg ttttgatgaa acattaatgg atgtaaagga
    23161 taaagtatat acaagggatt tgtttggaag agattaaggg agataggttt tgaacaagtt
    23221 ctattctcaa aaaatcacac cgttactatc ttcgaataaa ttaaaagcaa agcaagtgat
    23281 tgatagaaaa tcggctcttt gtcaactgta gtgggttgaa gaaaagctaa gctcgagaaa
    23341 ggacaaattt cgtcctttct tttttgatgt tcaaagtgat aacaatccgt tttttgaagt
    23401 tttcaaagtt tcgaaaacca aaggcattgc gcttgataag tttgatgaga ttattggtcg
    23461 cttccagttt ggcattagaa tagtgtagtt gaagggcgtt gacaatcttt tctttatctt
    23521 tgaggaaggt tttaaagaca gtctgaaaaa taggatgaac ctgcttaaga ttgtcctcaa
    23581 taagtccgaa aaatttctct ggttccttat tctggaagtg aaaaagcaag agttgataga
    23641 gctgatagtg gtgtttcaag tcttccgaat agctcaaaag cttgtttaaa atctctttat
    23701 tggttaagtg catacgaaaa gtaggacgat aaaatcgctt atcactcagt ttacggctat
    23761 cctgttgaat gagtttccag tagcgcttga tagccttgta ttcatgagac tttcgatcca
    23821 attgattcat gatttggaca cggatacgac tcatagcacg gctaagatgt tgtacaatgt
    23881 gaaagcgaag ctgtttagcc aagtcatagt aagggctaaa catatccata gtaatgattt
    23941 tgacgcgaca tcggacggct ctatcatatt taagaaagtg atctcggatg acagcttgtg
    24001 ttctaccctc aagaacagtg atgatatcga gcttttcaaa atcttgcgca ataaagctca
    24061 tctccatctc ccgattgaaa cagtcactcc ccggactgtt ttaacgtccc aggacataat
    24121 ctcaggaaga caagaaaaat catgtttaaa gtgaaaatca ttgagctttc gaatgacagt
    24181 tgaagttgaa atggccagct gatgggcaat atcggtcata gaattctttt caattaactt
    24241 ttgagcaatc ttttggttga tgatacgagg gatttggtga ttcttcttga ctatagaagt
    24301 ttcagcgacc atcatttttg aacagtgata gcacttgaat cgacgctttc taaggagaat
    24361 tctagtaggc ataccagtcg tttcaagata aggaatttta gaaggttttt gaaagtcata
    24421 tttcttcaat tggtttccgc actcagggca agatggggcg tcgtagtcca gtttggcgat
    24481 gatttccttg tgtgtatcct tattgatgat gtctaaaatc tggatattag tgtctttaat
    24541 gtctagtaat tttgtgataa aatgtaattg ttccatatga ttctttctaa tgagttgttt
    24601 tgtcgctttt cattataggt catatgggac tttttttcta caacaaaata ggctccataa
    24661 tatccatagg ggatttaccc actacaaata ttatagagcc agaaaatcac ctgctttttg
    24721 tatcaatgtt tttttcacaa aatctaaaat ataatggatt gaatttggaa tagaacacta
    24781 tggtttctaa agcattgtta gaaattatag tcaattgaaa caagagcagg acaaaagagc
    24841 ctcgtaaaag gtattgcaac ttggtaatac ctttttgatg tacgacgggc atgtcgtgca
    24901 tctgaggtgt aagtcctcgg tgggcacctg ctaccggtga acccaatagc gatttccaag
    24961 cctgactatc gtgaggtagc agggagagga agggatagcg aaatcgtggc tctacgaaca
    25021 ggaacgtgat agtaaggcgt atatagcgga taagggggcc tcaaactcta aagtccaaaa
    25081 aggtagtcgt aacctatatg cgtaaatcac gagagtaatt gaattcggac taaggtttgt
    25141 gtgaaaaaga taaatctttc tagagtctaa agactctgcg tcagatttcc tattttcact
    25201 gtaacctttt aacgtcctca tatcttgtat aaacgaggaa agatgtacga cttatcccgt
    25261 gaggtttcat gagcgctgaa agcgtagtaa caacgaatca tgagaagtca gccgagccca
    25321 tagtagtgag gaaacttccg taatggaagt ggagcgaagg ggtgaacaac taatcgaagt
    25381 aatcctactt cacttgtgtc tgtaaaatga gtggtctgat agaactggac tttgacacgt
    25441 aatgactaga tgaaggttca ccaatataag atgtccctca ggcaccaaaa caagaaagga
    25501 ataggcacat gtcaaaattg ctagataaaa tattatcacg cgaaaatatg ctggaagcct
    25561 acaatcaagt aaaatccgat aaaggctcag ctgggattga tggaatgact atcgaagaga
    25621 tggataatta tctcagacaa aactggcgct tgactaagga actgataaaa cagagaaaat
    25681 ataagcctca accagttctt agagttgaga tacctaaacc aggcggaggt atccgtcaac
    25741 taggaattcc aacagttatg gatagaatga ttcaacagac cattgtccaa gtcatgagcc
    25801 ccatttgtga accccatttc tcagatacga gttatggttt cagaccaaat aggtcatgtg
    25861 aaaaagccat catgaagctc ttagaatact taaatgacgg ctatgagtgg atagtggata
    25921 tagacctaga gaaatttttc gatacagttc ctcaagatag attgatgtcc ttagtacata
    25981 acattatcga agacggagat acggaatcct tgattcgtaa gtatcttcat tcaggtgtta
    26041 tcattaatgg tcaactttat aaaacactag ttggtacacc acagggagga aatttatctc
    26101 ctctcttatc caatatcatg cttaatgaat tggacaagga attagaaaag aggggacttc
    26161 gatttgtgcg ctacgcagat gattgtgtga ttacggtcgg aagcgaggca gcctctaagc
    26221 gtgtgatgta ttcagtcagt cgttttattg agaaacggct aggtttgaaa gtaaacatga
    26281 ccaagactaa gattaccaga ccaagagagt tgaaatatct aggttttggg ttctggaaat
    26341 catcagatgg ttggaaaagc cgtccacatc aagatagtgt tcggagattt aagtttaaat
    26401 tgaagaaact aacacagagg aaatggagta tagacctaac aagacgtatt gagcaactga
    26461 atttgtctat tcgaggatgg ataaactatt tctcattggg aaatatgaaa agtatagtcg
    26521 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
    26581 agaaatcgag acgattatgg ggattgctta agttaggggt tcctaaatgg atagcagata
    26641 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
    26701 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
    26761 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
    26821 gagaggggct agagattatc ccctactcta tgtgcttttt gatatgagcc catgttttct
    26881 caataggatt gtactcaggt gagtagggag gaagaggtaa aagtttatgc ccaaactctt
    26941 tgcataaaag ttctagcttc cccattctat ggaatcttgc attatccata ataataaccg
    27001 atggtgtggt taatgttggt aagagaaact tctgaaacca agcttcaaaa aagtcgctcg
    27061 tcatcatctc ttcgtaagtc attggagcga ttaactcacc atttgttaga cctgcaacca
    27121 aagaaatcct ctgatatctt cttccagata ctttgcctct tcttaactga ccttttaatg
    27181 agcgaccata ttctcgataa aaataagtat cgaatcctgt ttcatcaatc taaacaggtg
    27241 ataggtgctt taaactatta aaattcttaa gaaataaggc tactttttct gggtcttgtt
    27301 catagtaggt gtggttcttt ttttcgagtg tagtccatag ctttgagcgc atagtggatg
    27361 gtagttggat gacagccaaa ttcagaagct atttcagtca aataagcgtc tggattgtca
    27421 gtaagatagt ttttaagtct atctctatca acttttcttg gttttgttcc ttttacttgg
    27481 tggtttagct ctcctgtttt ctcttttagc tttaaccagc cataaatagt attacgtgag
    27541 atttggaaaa cgtgtgatgc ttctgttata ctacctgttc gctcacaata agagagaact
    27601 tttttacgaa aatctattga atatgccata agaagattat accacattgt gtactatttt
    27661 tggttcattt tactataatt taaaattccc tcatcgattt gttcacattc tattgcaatc
    27721 aactgtaaat atgcttttca gaatatatca aatataacaa atataacaaa taactaaaag
    27781 ttctataata gactccctgc gaaacaaaat atggtatagt agttctatga atgatgaagc
    27841 aagtaaacaa ctaaccgatg cacgatttaa gcgtcttgtt ggtgttcagc gtaccacttt
    27901 tgaagagatg ttagctgtat taaaaacagc ttatcaactt aaacacgcaa aaggtggacg
    27961 aaaacctaaa ttaagcctag aagaccttct tatggccact cctcactatg tgcgagaata
    28021 tcgaacttat gaagaaattg cggctgattt tggtatccac gaaagcaact tactccgtcg
    28081 gagccaatgg gttgaagtaa ctcttgttca aagtggtttt acgatttcaa gaactcctct
    28141 cagttctgag gacacggtaa tgattgatgc gacgaaagta aaaatcaatc gccctaaaaa
    28201 aagaattagc gaattattct ggtaaaaaga aatgccacgc tatgaagtct caggcgattg
    28261 tcacaagtca agggagaatt gtttctttgg atatcactgt gaactattgt catgatatga
    28321 agttgttcaa aatgagttgc agaaatatcg gacaagctgg taaaatcttg gccgacagtg
    28381 gttatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
    28441 tcaagccgct aacagctgaa gataaagcct gtaaccatgc gctatctaag gagagaagca
    28501 aggttgagaa catctttgcc aaagcatagt atattgaaac tagaatagta cacctctact
    28561 tctaaaacat tgttagaaat cgatttgact gccctgatcg attcgtccta ttcttgtttc
    28621 attttgatat aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct
    28681 tcggattacg aatgaatttg attgctgcta ttatcaatca tgaactagga ttctagtttt
    28741 gcaggaagtt taatgaagtt agccacccag ccctcctaaa aattagatgg ttcaactagc
    28801 tgaaagctct tgtaggcata agaaaacacc tctgtgttat acttgttgtt caaccacaaa
    28861 cacaagaaag gcacagaaat gcaagacaat tatactacaa aaggtaaaca tttgacaatc
    28921 gatagccgtc gcttaatcga aagatggaaa aaagaaggaa aatcaaatag agaaattgcc
    28981 tctctacttg gaaaagctcc tcaaactatc cacactgaaa tcaagcgtag gacagtccga
    29041 aaatgtcttg gaaaagggcg cttcaaagag gtttattctg ccgactatgc tcaacagtct
    29101 tatgaaaata atcgcaagca ctcggtcaag agatcaagcg tgaccaagga actaaaggaa
    29161 aagattctcc actatcataa ccaaaaattt ttgcctgaaa tgatggttat ggctaaaggg
    29221 gttaacgtgg gaatttcaac catttactat tggattcatc atggaaaatt ggggttaagc
    29281 aagcaggatc tgctttaccc tagaaaagga aaagcgctta agaaacaggc tagcaccaac
    29341 tttaaacctg ctggtcaatc catcgaacag cggcctgaag ctatcaatct tcgcttggag
    29401 aatgggcatt atgagattga tacggttcta cttacgagat cgaaaaacta ctgcttgctt
    29461 gtcttgacgg atcgaaagag tagacatcag atcatccgat tgattccaaa taaaagtgct
    29521 gaggtggtca atcaggctct aaaactcatc ttaaaacaac acaagattct ttccatcacg
    29581 gcagataatg gaacggaatt caatcgcttg tttgatatat tttctgagga gcacatctat
    29641 tatgcgcacc cctatgcctc ttgggaaagg ggaactaatg agaatcacaa caggctcatt
    29701 cgtagatagt tacctaaggg aaccaagaaa atgactccca aagaagtcgc attcatcgaa
    29761 aagtggatta acaactatcc taaaaaatgc ttggactaca agtcacccag agaagacttc
    29821 tggatggcta acttgaactt gaaatttagc tataacaaat aactcttaaa attctgaaaa
    29881 ttctgttgac aactttctga aaagagtcta taatggagag aaagttttaa aggagaaaat
    29941 gatgaaaagt tcaaaactat ttgcccttgc tggcgtgaca ttattggcgg cgactacttt
    30001 agctgcatgc tctggatcag gttcaagcgc taaaggtgag aagacattct catacattta
    30061 tgagacagac cctgataacc tcaactattt gacaactgct aaggctgcaa cagcaaatat
    30121 taccagtaac gtggttgatg gtttgctaga aaatgatcgc tacgggaact ttgtgccgtc
    30181 tatggctgag gattggtctg tatccaagga tggattgact tacacttata ctatccgtaa
    30241 ggatgcaaaa tggtatactt ctgaagggga agaatacgcg gcagtcaaag ctcaagac
//
