LOCUS       CR931635               20936 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 600/62 (serotype 4).
ACCESSION   CR931635
VERSION     CR931635.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20936)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 20936)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..20936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="600/62"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC04_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC04_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI32760.1"
                     /db_xref="GOA:Q4K1T1"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K1T1"
                     /translation="SNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL"
     gene            293..466
                     /gene="aliB"
                     /locus_tag="SPC04_0002"
                     /pseudo
     CDS             293..466
                     /gene="aliB"
                     /locus_tag="SPC04_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
                     /db_xref="PSEUDO:CAI32761.1"
     gene            complement(order(459..995,997..1323))
                     /gene="tnp"
                     /locus_tag="SPC04_0003"
                     /pseudo
     CDS             complement(join(459..995,997..1323))
                     /gene="tnp"
                     /locus_tag="SPC04_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(933..995,997..1305))
                     /gene="tnp"
                     /locus_tag="SPC04_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 1.9e-22"
                     /pseudo
     gene            1558..3003
                     /gene="wzg"
                     /locus_tag="SPC04_0004"
     CDS             1558..3003
                     /gene="wzg"
                     /locus_tag="SPC04_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI32763.1"
                     /db_xref="GOA:Q9AHD5"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q9AHD5"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTNNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKSQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRHQQKVIVAILQKLTST
                     EVLKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1558..1674
                     /gene="wzg"
                     /locus_tag="SPC04_0004"
                     /note="Signal peptide predicted for SPC0077 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1762..2109
                     /gene="wzg"
                     /locus_tag="SPC04_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 2.2e-63"
     misc_feature    2287..2730
                     /gene="wzg"
                     /locus_tag="SPC04_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 1.7e-69"
     gene            3005..3736
                     /gene="wzh"
                     /locus_tag="SPC04_0005"
     CDS             3005..3736
                     /gene="wzh"
                     /locus_tag="SPC04_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI32764.1"
                     /db_xref="GOA:Q4K337"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K337"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    3008..3616
                     /gene="wzh"
                     /locus_tag="SPC04_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 3e-37"
     gene            3742..4437
                     /gene="wzd"
                     /locus_tag="SPC04_0006"
     CDS             3742..4437
                     /gene="wzd"
                     /locus_tag="SPC04_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI32765.1"
                     /db_xref="GOA:Q9AHD3"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q9AHD3"
                     /translation="MMKEQNTIEIDVFQLVKSLWKRKLMILIVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDVLEEVVSDLKL
                     DLTPKGLANKIKVTVPVDTRIVSISVNDRVPEEASRIANSLREVAAQKIISITRVSDV
                     TTLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLHLELLDTRVKRPEDIENTLQM
                     TLLGVVPNLGKLK"
     misc_feature    3763..4179
                     /gene="wzd"
                     /locus_tag="SPC04_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 3.8e-56"
     misc_feature    4285..4362
                     /gene="wzd"
                     /locus_tag="SPC04_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4447..5130
                     /gene="wze"
                     /locus_tag="SPC04_0007"
     CDS             4447..5130
                     /gene="wze"
                     /locus_tag="SPC04_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI32766.1"
                     /db_xref="GOA:Q4K335"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K335"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSINIAWSFARAGYKTLLIDGDTRNSVMLGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIIDTPPIGIVI
                     DAAIITQKCDASILVTATGEANKRDIQKAKQQLKQTGKLFLGVVLNKLDISVNKYGVY
                     GSYGNYGKK"
     gene            5143..5253
                     /gene="HG261"
                     /locus_tag="SPC04_0008"
                     /pseudo
     CDS             5143..5253
                     /gene="HG261"
                     /locus_tag="SPC04_0008"
                     /note="member of homology group 261"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenylphosphate glucosephosphotransferase
                     WchA (initial sugar transferase) (fragment)"
     gene            5471..6106
                     /gene="wciI"
                     /locus_tag="SPC04_0009"
     CDS             5471..6106
                     /gene="wciI"
                     /locus_tag="SPC04_0009"
                     /note="member of homology group 29"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32768.1"
                     /db_xref="GOA:Q9AHD1"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q9AHD1"
                     /translation="MKNGNRIYSWRLFMYGIIKRLGDILLSLIGIIILCPVFMIIAIA
                     IKLDSEGPVIFKQKRFGIHKEYFYILKFRSMKIDAPKNVAPRNLYNPEQWITKVGAFL
                     RKTSLDELPQLFNILVGNMSIVGPRPAGINELDLIAERDKYGANDILPGLTGWAQING
                     RDTLSVEMKTELDGYYVKHLSLIMDIRCIVKTIPYVLKRKGIVEGSGKKES"
     misc_feature    5471..5602
                     /gene="wciI"
                     /locus_tag="SPC04_0009"
                     /note="Signal peptide predicted for SPC0082 by SignalP 2.0
                     HMM (Signal peptide probability 0.809) with cleavage site
                     probability 0.562 between residues 44 and 45"
     misc_feature    5525..6079
                     /gene="wciI"
                     /locus_tag="SPC04_0009"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 4.3e-37"
     gene            6115..7344
                     /gene="wciJ"
                     /locus_tag="SPC04_0010"
     CDS             6115..7344
                     /gene="wciJ"
                     /locus_tag="SPC04_0010"
                     /note="member of homology group 35"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32769.1"
                     /db_xref="GOA:Q97SJ5"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q97SJ5"
                     /translation="MKILFVCQHYKPEPFRLSDICEDLVRKGHEVSVLAGIPNYPEGK
                     IYADYRHNKKRREIIEGVTIYRSYTIPRKKSVVFRLLNYFSFAISSTLGVLLGRYKTK
                     DGSNFDCVFVNQLSPVMMAWAGMAYKKKYKKPMFLYCMDVWPDSLTVGGVKQDGLIFK
                     LFKFISKKVYRASDYIFVTSPSFKNYFVKQFDISEQKITYLPQYAEDLFIPDESIVNK
                     ESVDLTFAGNIGKAQNLETILKAASLIEKNTNLPKKIHFHFVGDGTELLSMKALAHEL
                     ELKNISFYGRRSLEEMPSFYKKSDAMLVSLIGDSIVSRTIPGKVQSYMAAGKPIIGAI
                     SGDAKIIVEEANCGYVSPERDVKQLAKNICKFSMLSIKRQRELGKKARCYYENHFSKE
                     QFMLELETCLERESKKE"
     misc_feature    6733..7266
                     /gene="wciJ"
                     /locus_tag="SPC04_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 2.1e-12"
     gene            7349..8425
                     /gene="wciK"
                     /locus_tag="SPC04_0011"
     CDS             7349..8425
                     /gene="wciK"
                     /locus_tag="SPC04_0011"
                     /note="member of homology group 212"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32770.1"
                     /db_xref="GOA:Q4K332"
                     /db_xref="UniProtKB/TrEMBL:Q4K332"
                     /translation="MRVLFILSDNIYLTPYFNFYKELLKKLSISYDVIYWDKNINEII
                     TKQNYYRISFSGKGKLSKILGYVKFRKEIKKKLKENDYDMILPLHSIVSFILVDFLLF
                     SFKNRYIYDIRDYSYEKFLVYRLVQKQLVKNSLMNIVSSDGYKFFLPMGEYFTTHNLP
                     NMIELNEVKQLKNNSTFPIQLSYIGLIRFQEQNKKIIDFFANDSRFQLNFIGTNAGEL
                     REFCQEKNISNVNLVDTFQPKDTMSFYKNTDAVLNLYGNHTPLLDYALSNKLYFAALL
                     YKPILVCEDTYMEKVSIENGFGFVLPMKDESEKDCLALYIQNLDRKQLIKNCDNFMDR
                     ISLEKQKTEIELEKRILSLRKKND"
     gene            8418..9536
                     /gene="wciL"
                     /locus_tag="SPC04_0012"
     CDS             8418..9536
                     /gene="wciL"
                     /locus_tag="SPC04_0012"
                     /note="member of homology group 30"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32771.1"
                     /db_xref="GOA:Q9AHC8"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q9AHC8"
                     /translation="MIKVLHLFTTLDSGGVESFLFNYYSHIDRKKIQFDFIVPGKEQG
                     FLEDKMKELGAKVYHVPLLRKKPLHQFLSLARIIKKGDYDIVHCHGYKSAIGLILSKI
                     IGCKIRIIHSHMAYVTENSFQKVLRKLVTILVKILATHWFACGEDSAKWLYGEKAYKD
                     GKIEIIFNAIDLKKYQFLSDVREKCRRELDVSNKFVLGNIARLSDQKNQSYLFNVLKE
                     LILIKPNVILLLVGNGEDEQKLKQKALELNLTPYVLFLGRRTDISDLLSAMDVFLLPS
                     KYEGLPVSLVEAQASGLQILSSDTVTQEVDVTKNISYLPINEESVLLWKDKVLSLTSE
                     ECNRFEINNSMTDGLYDICYQASKLLNRYQEMCVIKEI"
     misc_feature    8961..9455
                     /gene="wciL"
                     /locus_tag="SPC04_0012"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 2.6e-26"
     gene            9537..10937
                     /gene="wzy"
                     /locus_tag="SPC04_0013"
     CDS             9537..10937
                     /gene="wzy"
                     /locus_tag="SPC04_0013"
                     /note="member of homology group 213"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI32772.1"
                     /db_xref="UniProtKB/TrEMBL:Q9AHC7"
                     /translation="MQTKYICRVTLVTLSFIFAFCYLFWTLDNWNNGFLISNYVPSIF
                     IWVCFLIIFQITGFILQKVSIYDFSVWYLILSYFFMFGLIFNEYMGFQTTLLWSPSNF
                     YNNEELFHSYIFIIWILFCYSVGYLFFYSDGKVHYHSEVQNYQENEEKILYNAGRILT
                     GVGFISRVITDSKTVLAVRAANSYSAYSEAASSGIIDDLGVLMLPGVFSLFYSDKLSR
                     VIKRTIFWVMLFYLILIMILTGSRKIQVFSILALVLVYTQSLGITFSKKRVLVFLIVT
                     VFLLNVLVVIRGHRFDLNTIGIYLFDSFSSLDFVKNILGEVFSESGLTSLTVASAVTV
                     VPSSIPYEYGMTFLRTILSIFPIGWLVGDFFDKASATVVINKFLGLPVGSSFVEELFW
                     NFGYYGGVFWSFVLGIFSGWRLNFRAFQTSKISKVIYFSVISQLLLLVRSSSIDVYRP
                     IMYSLIMIFIFRRLKK"
     gene            10937..12019
                     /gene="wciM"
                     /locus_tag="SPC04_0014"
     CDS             10937..12019
                     /gene="wciM"
                     /locus_tag="SPC04_0014"
                     /note="member of homology group 214"
                     /codon_start=1
                     /transl_table=11
                     /product="putative pyruvyl transferase WciM"
                     /protein_id="CAI32773.1"
                     /db_xref="GOA:Q97SJ4"
                     /db_xref="InterPro:IPR007345"
                     /db_xref="UniProtKB/TrEMBL:Q97SJ4"
                     /translation="MVKKIMLHGATDYGSSNYGDYLYGEIVYDLLESKGYEVSFYNPS
                     DFFQMYLKEYRQKQSFTKKQADAILYIPGGYFGEGHNARFRDNLIQFKRFLPLGIWAS
                     YFKKPIGVLGIGAGPNNDSLMNYGIKRIINHAQFITVRDRESFDSLKHLSPSAPVHET
                     FDLIISSKLREEKTEQLCQLKREAKDKKIILVHYNHSKKALEKFAESISLFLENNPNY
                     YVVVTSDSILPYEDAYYQEFRKLVRTEDCFQFKYHSPAEMTSLLKMVDVVLTCKLHVG
                     VVATCFNKSVIAIACHPEKTARYYGAIGELQRCESLFDSSVNSIVKKLETFHLKPITI
                     PSELVLKARSSLDYLDLFLEGLVRES"
     misc_feature    10952..11986
                     /gene="wciM"
                     /locus_tag="SPC04_0014"
                     /note="HMMPfam hit to PF04230, Polysaccharide pyruvyl
                     transferase, score 5.9e-109"
     gene            12009..13250
                     /gene="wzx"
                     /locus_tag="SPC04_0015"
     CDS             12009..13250
                     /gene="wzx"
                     /locus_tag="SPC04_0015"
                     /note="member of homology group 215"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI32774.1"
                     /db_xref="GOA:Q97SJ3"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q97SJ3"
                     /translation="MKVDRISFIKNTSSLYILNIVKLLFPLLTLPYLTRVLSLDAYGM
                     VIYVKALIAYVQLVIDFGFMISATKNIVNACTTPSKIGRIVGDTLVEKIFLSIISILI
                     YTILMWQIPIMRENILFSVFYLLATVTNIFIFDFLFRGIEKMHAVAIPYIISKTIITI
                     LTFIVVKDDSSILWIPILEGIGNLVAAVVSYRFLHYYGIKLSFSYLSVWVKDLKESSI
                     YFLSNFATTIFGVFTTVISGFYLQSQEIAFWGIAMQLLSAAKSLYNPIANSLYPHMIR
                     TKDIQSVKSINRIMFIPIIFGVLIVLFFSNQILSIIGGEKYTVSADFLKYLLPAFVAS
                     FYSMIYGWPVLGAIDKVKETTMTTILASIVQTLGLGIFILSDNFSLVTLAICSSMSEV
                     VLWISRYLIYFKNRSLFVRSK"
     misc_feature    12030..12842
                     /gene="wzx"
                     /locus_tag="SPC04_0015"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.4e-23"
     gene            13255..14352
                     /gene="mnaA"
                     /locus_tag="SPC04_0016"
     CDS             13255..14352
                     /gene="mnaA"
                     /locus_tag="SPC04_0016"
                     /EC_number="5.1.3.14"
                     /note="member of homology group 23"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine-2-epimerase MnaA"
                     /protein_id="CAI32775.1"
                     /db_xref="GOA:Q9AHC4"
                     /db_xref="HSSP:1O6C"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q9AHC4"
                     /translation="MKKVVVVFGTRPEAIKMCPLVKELRTRKNIETLVCVTGQHRQML
                     DQVLDTFGIIPDFDLSIMKDKQTLFDVTIGILEGMKAILESEKPDLVLVHGDTSTTFA
                     SSLAAFYLQIPIGHVEAGLRTYDIYSPYPEEFNRQAVGVLAQYHFTPTQLSKDNLLRE
                     GKTPESIFVTGNTAIDALQTTIQEDYTHPELEWIGESRFILITAHRRENLGEPMRHMF
                     RAIRRIIEEYSDVKAIYPIHMNPRVRQIAEEELSGCERIKMIEPLEVLDFHNFLSRSY
                     LILTDSGGIQEEAPSLGKPVLVMRDTTERPEGIEAGTLKLVGADENNIYRHFKELLEN
                     DSVYQAMSQASNPYGDGTACKKIADILEGEV"
     misc_feature    13318..14340
                     /gene="mnaA"
                     /locus_tag="SPC04_0016"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 1.3e-183"
     gene            14356..15411
                     /gene="fnlA"
                     /locus_tag="SPC04_0017"
     CDS             14356..15411
                     /gene="fnlA"
                     /locus_tag="SPC04_0017"
                     /note="member of homology group 36"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlA"
                     /protein_id="CAI32776.1"
                     /db_xref="GOA:Q9AHC3"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR013692"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q9AHC3"
                     /translation="MSQFTGKTLLITGGTGSFGNAVLKRFLETDVSEIRIFSRDEKKQ
                     DDMRHEFQVKVPEVAGKIRFYLGDVRDLASVKNAMHGVDYVFHAAALKQVPSCEFFPV
                     EAVKTNILGTENVLTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAMMEKIAVAKSRTV
                     NPEHTKICVTRYGNVLCSRGSVVPLWIEQIKQGNALTITEPSMTRFVMTLEEAVDLVL
                     FAFEEGKSGDILVQKAPACTIEVLAKAVSEIFASEQDIKIIGIRHGEKRYETLLTNEE
                     CANAIDLGDFYRVPSDNRNLNYDKYFKDGSTNRNLLTEFNSNNTDLMDVEQVKRKLLE
                     LDEIQTAIRDMVADEEM"
     misc_feature    14377..15231
                     /gene="fnlA"
                     /locus_tag="SPC04_0017"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00099"
     misc_feature    14380..15051
                     /gene="fnlA"
                     /locus_tag="SPC04_0017"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 4.8e-09"
     misc_feature    14380..15228
                     /gene="fnlA"
                     /locus_tag="SPC04_0017"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 1.2e-162"
     misc_feature    14383..15018
                     /gene="fnlA"
                     /locus_tag="SPC04_0017"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 5.8e-09"
     misc_feature    15229..15372
                     /gene="fnlA"
                     /locus_tag="SPC04_0017"
                     /note="HMMPfam hit to PF08485, Polysaccharide biosynthesis
                     protein C, score 2e-23"
     gene            15511..16740
                     /gene="fnlB"
                     /locus_tag="SPC04_0018"
     CDS             15511..16740
                     /gene="fnlB"
                     /locus_tag="SPC04_0018"
                     /note="member of homology group 37"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlB"
                     /protein_id="CAI32777.1"
                     /db_xref="GOA:Q97SJ2"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q97SJ2"
                     /translation="MIKNILITGAKGFVGKNLICTLEALKDGRDRTRPNLEIGEIFQY
                     DRDTDPILLDEYCKKADFVFHLAGVNRPQNPDEFMEGNYGFSSRLLEILEKYENTCPV
                     LLSSSTQASLEGRFSNSIYGQSKLAGEELFFEYGKKTGAPVLVYRFPNLYGKWCRPNY
                     NSAVATFCYNLAHDLPIQVNDPSVELELLYIDDLIQECLTALEGNPHRCNLDGLQILP
                     SPSGNYCYVPTTHRATLGEIVSLLETFKKQPDSLVMPEIPQGSFKKKLYSTYLSYLPV
                     DKFKFPLKMNIDERGSFTELLKTENTGQFSVNISKPGITKGQHWHHSKWEFFMVVSGR
                     ALIQERRIGLDENGQEYPILNFEVSGDKIEAIHMIPGYAHNIINLSDTENLITVMWAN
                     ESFDPRHPDTFFEQVEK"
     misc_feature    15523..16146
                     /gene="fnlB"
                     /locus_tag="SPC04_0018"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 8.6e-09"
     gene            16741..17925
                     /gene="fnlC"
                     /locus_tag="SPC04_0019"
     CDS             16741..17925
                     /gene="fnlC"
                     /locus_tag="SPC04_0019"
                     /note="member of homology group 38"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-L-fucosamine FnlC"
                     /protein_id="CAI32778.1"
                     /db_xref="GOA:Q9AHC1"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q9AHC1"
                     /translation="MKIKTDYSDIHFKDNGKLKLLIIVGTRPEIIRLSSVITKCRKYF
                     DVILAHTGQNYDYNLNGIFFDNLGLDTPDVYMDAVGDDLGATVGNIINTSYKLMNQIK
                     PDALLILGDTNSCLSAIAAKRLHIPIFHMEAGNRCKDECLPEETNRRIVDVISDVNLA
                     YSEHARKYLHECGLPKERTYVTGSPMAEVLHKNLSAIESSDIHERLGLKKGGYILLSA
                     HREENIDTDKNFISLFTAINQLAEKYNMPILYSCHPRSKKRLQESGFKLDKRVIQHEP
                     LGFHDYNCLQMNAFVVVSDSGTLPEESSFFTSQGYPFPAVCIRTSTERPESLDKAGFI
                     LAGIDENSLLQAVETAVSLAQDEDFGLPVPDYVEENVSTKVVKIIQSYTGIVDKIVWR
                     KS"
     misc_feature    16852..17880
                     /gene="fnlC"
                     /locus_tag="SPC04_0019"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 8.3e-105"
     gene            complement(18120..18209)
                     /gene="tnp"
                     /locus_tag="SPC04_0020"
                     /pseudo
     CDS             complement(18120..18209)
                     /gene="tnp"
                     /locus_tag="SPC04_0020"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS element transposase (fragment)"
     gene            complement(18291..19362)
                     /gene="tnp"
                     /locus_tag="SPC04_0021"
                     /pseudo
     CDS             complement(join(18291..18608,18610..19362))
                     /gene="tnp"
                     /locus_tag="SPC04_0021"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     gene            19465..19650
                     /gene="tnp"
                     /locus_tag="SPC04_0022"
                     /pseudo
     CDS             19465..19650
                     /gene="tnp"
                     /locus_tag="SPC04_0022"
                     /note="member of homology group 0047 7"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            complement(19886..20457)
                     /gene="tnp"
                     /locus_tag="SPC04_0023"
                     /pseudo
     CDS             complement(join(19886..20209,20193..20393,20392..20457))
                     /gene="tnp"
                     /locus_tag="SPC04_0023"
                     /note="member of homology group 31"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase"
     misc_feature    complement(19889..20191)
                     /gene="tnp"
                     /locus_tag="SPC04_0023"
                     /note="HMMPfam hit to PF05717, IS66 Orf2 like protein,
                     score 9e-53"
                     /pseudo
     gene            20577..>20936
                     /gene="aliA"
                     /locus_tag="SPC04_0024"
     CDS             20577..>20936
                     /gene="aliA"
                     /locus_tag="SPC04_0024"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI32783.1"
                     /db_xref="GOA:Q4K2T2"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K2T2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    20577..20663
                     /gene="aliA"
                     /locus_tag="SPC04_0024"
                     /note="Signal peptide predicted for SPC0098 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    20823..20891
                     /gene="aliA"
                     /locus_tag="SPC04_0024"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     6774 a   3126 c   4156 g   6880 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acactgcggc taaagaagta cttgaaaaac aggtcttggc tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaagttt ataaactttc
      241 attcttgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga agatgaacat
      301 aaagaagcgt gtccttagtg caggcctgac ttttgcatct gctttgcttt tagctgcttg
      361 cggccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaactat ctattagact attacgctga taatatagtc aattgaaaca agaacaagac
      481 aaaagagcct cataaaaggt attgcaactt ggtaatacct ttttgaggtg ctttttgata
      541 tgagcccatg ttttctcaat aggattgtac tcaggtgagt agggaggaag aggtaaaagt
      601 ttatacccaa actcttcaca caagagttct aacttaccca ttctatggaa tcttgcatta
      661 tccataataa taaccgatgg tgtgtttaat gttggtaaga gaaatttctg aaaccaagct
      721 tcaaaaaagt cgctcgtcat cgtctcttcg taagttattg gagcgattaa ctcaccattt
      781 gttagacctg caaccaaaga aatcctctga tatcttcttc cagatacttt gcctcttctt
      841 aactgacctt ttaatgagcg accatattct cgataaaaat aagtatcgaa tcctgtttca
      901 tcaatctaaa caggtgctag gtgctttaaa ctattaaaat tcttaagaaa taaggctact
      961 ttttctgggt tttgttcata gtaggtgtgg ttcttttttt cgagtgtagc ccatagcttt
     1021 gagcgcatag tggatggtag ttggatgaca gccaaattca gaagctattt cagtcaaata
     1081 agcgtctgga ttgtcagtaa gatagttttt aagtctatct ctatcaactt ttcttggttt
     1141 tgttcctttt acttggtggt ttagctctcc tgttttctct tttagcttta accagccata
     1201 aatggtatta cgtgatattt ggaaaacgtg tgatgcttct gttatactac ctgttcgctc
     1261 acaataagag agaacttttt tacgaaaatc tattgaatat gccataagaa gattatacca
     1321 cattgtgtac tatattagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
     1381 agaaatcgat ttgactgtcc tgaacgattt gttctgttct tatttcattt tactatattt
     1441 ttgtttcgcg ggaagtctac taagatactt aaagatgcag atagtaaaaa taaaggtgta
     1501 gacattaccg taaaaaagtg atataatcgt ataatgttca atgtataggt attaattatg
     1561 agtagacgtt ttaaaaaatc acgttcacag aaagtgaagc gaagtgttaa tatagttttg
     1621 ctgactattt atttattgtt agtttgtttt ttattgttct taatctttaa gtacaatatc
     1681 cttgctttta gatatcttaa tctagtggta actgcgttag tcctactagt tgccttggta
     1741 gggctactct tgattatcta taaaaaagct gaaaagttta ctatttttct gttggtgttc
     1801 tctatccttg tcagctctgt gtcgctcttt gcagtacagc agtttgttgg actgaccaat
     1861 cgtttaaatg cgacttctaa ttactcagaa tattcaatca gtgtcgctgt tttagcagat
     1921 agtgagatcg aaaatgttac gcaactgacg agtgtgacag caccgactgg gactaataat
     1981 gaaaatattc agaaattact agctgatatc aagtcaagtc agaataccga tttgacggtc
     2041 aaccagagtt cgtcttactt ggcagcttac aagagtttga ttgcagggga gactaaggcc
     2101 attgtcctaa atagtgtctt tgaaaacatc atcgagtcag agtatccaga ctacgcatcg
     2161 aagataaaaa agatttatac taagggattc actaaaaaag tagaagctcc taagacgtct
     2221 aagagtcagt ctttcaatat ctatgttagt ggaattgaca cctatggtcc tattagttcg
     2281 gtgtcgcgat cagatgtcaa catcctgatg actgtcaatc gagataccaa gaaaatcctc
     2341 ttgaccacaa cgccacgtga tgcctatgta ccaatcgcag atggtggaaa taatcaaaaa
     2401 gataaattga ctcatgcggg catttatgga gttgattcgt ccattcacac cttagaaaat
     2461 ctctatggag tggatatcaa ttactatgtg cgattgaact tcacttcgtt tttgaaattg
     2521 attgatttgt tgggtggaat tgatgtttat aatgatcaag aatttactgc ccatacgaat
     2581 ggaaagtatt accctgcagg caatgttcat cttgattcag aacaggctct cggttttgtt
     2641 cgtgagcgct actccctagc agatggcgat cgtgaccgcg ggcgccatca acaaaaggtg
     2701 attgtggcta tccttcaaaa attaacgtca accgaagtgc tgaaaaatta tagtacgatc
     2761 attaatagct tgcaagattc tatccaaaca aatatgccac ttgagaccat gataaatttg
     2821 gtcaatgctc agttagaaag tggagggaat tataaagtaa attctcaaga tttaaaaggg
     2881 acaggtcgga tggatcttcc ttcttatgca atgccagaca gtaacctcta tgtgatggaa
     2941 atagatgata gtagtttagc tgtagttaaa gcagctatac aggatgtgat ggagggtaga
     3001 tgaaatgata gacatccatt cgcatatcgt ttttgatgta gatgacggtc ccaagtcaag
     3061 agaggaaagc aaggctctct tggcagaatc ctacagacag ggggtgcgaa ccattgtttc
     3121 tacctctcac cgtcgcaagg gcatgtttga aactccggaa gagaagatag cagaaaactt
     3181 tcttcaggtt cgggaaatag ctaaggaagt ggcgagtgac ttggtcattg cttacggggc
     3241 tgaaatttat tacacaccag atgttctgga taagctggaa aaaaagcgga ttccgaccct
     3301 caatgatagt cgttatgcct tgatagagtt tagtatgaac actccttatc gcgatattca
     3361 tagcgccttg agcaagatct tgatgttggg aattactcca gtcattgccc acattgagcg
     3421 ctatgatgct cttgaaaata atgaaaaacg cgttcgagaa ctgatcgata tgggctgtta
     3481 cacgcaagta aatagttcac atgtcctcaa acccaaactt tttggcgaac gttataaatt
     3541 catgaaaaaa agagctcagt attttttaga gcaggatttg gttcatgtca ttgcaagtga
     3601 tatgcacaat ctagacggta gacctcctca tatggcagaa gcatatgacc ttgttaccca
     3661 aaaatacgga gaagcgaagg ctcaggaact ttttatagac aatcctcgaa aaattgtaat
     3721 ggatcaacta atttaggaga aatgatgaaa gaacaaaata cgatagaaat cgatgtattt
     3781 caattagtta aaagcttgtg gaaacgcaag ctaatgattt taatagtggc acttgtgaca
     3841 ggtgcggggg cttttgcata tagcactttt attgttaagc cagaatatac gagtaccacg
     3901 cgaatttacg tagtgaatcg caatcaagga gacaagccgg ggttgacaaa tcaggatttg
     3961 caggcaggaa cttatctggt aaaagactac cgtgagatta tcctttcgca ggatgttttg
     4021 gaggaagttg tttctgattt gaaactagat ttgacgccaa aaggtttggc taataaaatt
     4081 aaagtgacag taccagttga tacccgtatt gtctctattt cagttaatga tcgagttcct
     4141 gaagaggcaa gccgtatcgc taactctttg agagaagtag ctgctcaaaa aattatcagt
     4201 attactcgtg tttctgacgt gacaacactg gaggaggcaa ggccggcgat atccccgtct
     4261 tcgccaaata ttaaacgcaa tacactaatt ggttttttgg caggggtgat tggaactagt
     4321 gttatagttc ttcatcttga acttttggat actcgtgtga aacgtccgga agatatcgaa
     4381 aatacattgc agatgacact tttgggagtt gtgccaaact tgggtaagtt gaaataggag
     4441 agaaggatgc cgacattaga aatagcacaa aaaaaactgg agttcattaa gaaggcagaa
     4501 gaatattaca atgccttgtg tacaaatata cagttgagcg gagataaact aaaagtaatt
     4561 tccgttactt ctgttaaccc tggggaagga aaaacaacta cttccataaa tatagcatgg
     4621 tcgtttgcgc gtgcaggcta taaaactctt ttgatcgatg gcgatactcg aaattcagtt
     4681 atgttaggag tttttaaatc tcgtgaaaaa attacagggc taacagaatt tttatctggg
     4741 acagctgatt tatctcacgg tttatgtgat acaaatattg aaaatttatt tgtagttcaa
     4801 tcgggatctg tatcaccaaa ccctacagcc ttgttacaaa gtaaaaattt taatgatatg
     4861 attgaaacat tgcgtaaata ttttgattat atcattattg atacaccgcc tattggaatt
     4921 gttattgatg cggcaattat cactcaaaag tgtgatgcgt ccatcttggt aacagcaaca
     4981 ggtgaggcga ataaacgtga tatccaaaaa gcgaaacaac aattaaaaca aacagggaaa
     5041 ctgttcctag gagttgtttt aaataaattg gatatctcgg ttaataagta tggagtttac
     5101 ggttcctatg gaaattatgg taaaaaataa aatgaatata gtatggaagg ggactacaat
     5161 ataactctgg cattcttaca gagcatactt atcagtttat tagcttatgt actgattgca
     5221 atttcagaaa ccgatatgtc ttcaaataat attcggtcta tttggaagaa taattgaact
     5281 ggaccttcta attcattatt gagaactcat atattactga aacaaataaa ttttgtttag
     5341 atggagaaaa gttttatctg acgtagagga taaaagaatt atatttctga aaatcattga
     5401 gtgaccaaat atatattgag tttctgtagt tgcatgtact gcctgattta atttgtcaaa
     5461 tggaaataga atgaaaaatg gaaatagaat ttatagttgg aggttgttta tgtacggtat
     5521 aataaaacga ttaggtgata tattattatc tttaataggg ataataatat tgtgtccggt
     5581 ttttatgata attgcaattg cgattaaact tgattcagaa ggtccggtta tatttaagca
     5641 aaaacgcttt ggtattcata aagaatactt ctatattttg aaatttaggt ctatgaaaat
     5701 agatgcacct aaaaatgtgg cgcctcgaaa cttatataat ccagagcaat ggattacaaa
     5761 agtaggggct ttcttgcgaa aaacatcttt ggatgaacta ccacaattgt ttaatattct
     5821 tgttggtaat atgagtattg taggtcctag accagcgggt ataaatgaac tagatttgat
     5881 tgcagagaga gataagtatg gagcaaatga tatcttgcca gggttaactg gatgggcaca
     5941 aattaacggg cgtgatactt tgtctgttga gatgaagacg gagttagatg gctactatgt
     6001 taaacatctg tctttgataa tggatattag atgtatagtt aagacaatac cttacgtact
     6061 gaaacgaaaa ggtattgtag agggtagtgg taagaaagaa agttaaattg gacaatgaaa
     6121 atactatttg tttgccaaca ttataagcca gaaccattca ggttgtcaga tatttgtgaa
     6181 gatttagttc gaaaagggca tgaagtctct gttttggctg ggattcctaa ttaccctgaa
     6241 gggaagatat atgcagatta tcgtcataat aaaaaaagac gtgagattat agaaggtgtt
     6301 acgatatatc gttcttatac aatccctaga aaaaaaagtg ttgtatttcg attgttgaat
     6361 tattttagct ttgcaattag ttctacttta ggagttttat tggggaggta taaaacgaaa
     6421 gatggatcga attttgactg tgtattcgtt aaccaattgt ctccagttat gatggcatgg
     6481 gctggtatgg cttataaaaa aaaatataag aaaccgatgt ttctatattg tatggatgtt
     6541 tggccagata gtttaaccgt aggtggagtg aaacaagatg gcttgatttt caagctgttt
     6601 aaatttatct caaaaaaagt ttaccgagct agtgattata tatttgtcac tagtccatca
     6661 tttaaaaatt attttgtgaa gcaatttgac atatccgaac aaaagattac atatttgcca
     6721 caatatgcag aagatctttt tatccctgat gaatctatag ttaataaaga aagtgttgac
     6781 ctaacttttg ctggtaatat tggcaaagca caaaatttgg aaactatttt gaaagctgcc
     6841 agtttgatag agaagaatac caatttaccc aagaaaattc attttcattt tgttggagat
     6901 ggtacggaat tgttaagcat gaaagcatta gctcatgaat tggagttaaa gaatatttcc
     6961 ttctatggaa gacgttcttt ggaggaaatg ccatccttct ataaaaaatc agatgctatg
     7021 ttagtttctt taataggaga ctcgatagtt tctcgtacta tacctgggaa ggtacaatct
     7081 tatatggcgg caggcaaacc aattataggt gcaatttcag gagatgctaa aataattgta
     7141 gaagaagcaa attgtggata tgttagtccc gaacgagatg taaaacaatt ggcaaaaaat
     7201 atttgtaaat ttagtatgtt atctattaag agacaaagag agttaggaaa gaaagctcgt
     7261 tgttactatg aaaatcactt ttcaaaagag cagtttatgc tcgaactgga gacatgttta
     7321 gagagggaaa gtaagaaaga ataatttaat gagagtactg tttatactat ctgataatat
     7381 atatctaact ccttacttca atttttataa agaattattg aagaaactgt ctattagtta
     7441 cgatgttata tattgggata agaatattaa cgagattatt acaaaacaaa actactatcg
     7501 tatttctttt tctggtaaag gaaaattaag taagatatta ggttatgtaa aattcagaaa
     7561 agaaattaaa aagaagctaa aagaaaatga ttatgatatg atattgccgt tacatagtat
     7621 tgtgtctttc attttagtag attttcttct cttttcattt aaaaatagat atatttatga
     7681 tattcgtgat tacagttatg aaaaattttt ggtttatcgt ttggttcaga aacaattggt
     7741 gaaaaattct ttaatgaata tcgtttcttc agacggctat aaattttttt taccaatggg
     7801 agagtatttt actacccata acctacccaa tatgatagaa ttaaacgagg taaagcagtt
     7861 aaaaaataat agtacgtttc caattcaact ttcctacatt ggtttaattc gttttcaaga
     7921 acaaaataaa aaaataatcg atttttttgc aaatgacagt cgatttcagt tgaattttat
     7981 aggtactaat gcaggagaat taagggaatt ttgtcaagaa aaaaatatca gcaatgttaa
     8041 cttggtggac acattccagc ctaaagatac catgtctttt tataagaata cagatgctgt
     8101 tttgaattta tacgggaatc acactccctt actagactat gctttgtcta ataaactcta
     8161 ctttgctgca ttgttgtata aacctatttt agtttgtgaa gatacttata tggaaaaagt
     8221 gtcaatagag aatggttttg gtttcgtttt acctatgaag gatgaatcgg aaaaagattg
     8281 tttggctttg tatattcaaa accttgacag gaaacagcta attaagaatt gtgataactt
     8341 catggacaga attagtttag aaaaacaaaa aacagaaata gaattagaga agcgaatctt
     8401 aagcttaagg aagaagaatg attaaagtat tacatctatt tacaacacta gatagtggtg
     8461 gagtagaaag ttttctattc aactattatt ctcacattga tagaaaaaaa attcaatttg
     8521 attttattgt gcctggaaaa gaacaaggat ttttagagga taaaatgaaa gaattgggtg
     8581 caaaggttta tcatgtgcct ctattaagga aaaagcctct acatcagttt ctctctcttg
     8641 ctagaataat aaagaaagga gattatgata tagttcattg ccatggctat aaatctgcaa
     8701 ttggtctgat cttatctaaa ataattggtt gtaaaattag aattattcat agtcatatgg
     8761 cttatgtaac agaaaacagt tttcaaaaag tattgcgtaa attagtaaca attttggtaa
     8821 aaatcttagc aactcattgg tttgcatgtg gggaagattc ggctaagtgg ttatatggag
     8881 agaaagcgta taaagacgga aaaattgaaa ttatttttaa tgcaattgat ttgaaaaagt
     8941 atcaattttt gtcagatgtt agagaaaaat gtcgtagaga attagatgtg tcaaataagt
     9001 tcgtattagg aaatatagct cgcctatcag atcaaaaaaa ccaaagttat ttatttaacg
     9061 ttttaaaaga actcatttta atcaaaccaa atgttatttt actcctagtt ggtaatggtg
     9121 aggatgagca gaaattaaaa cagaaagctt tagaactaaa tctgacccca tatgtgctat
     9181 ttttagggag aaggactgat atttctgatt tattatctgc gatggatgtt tttttgcttc
     9241 cgtctaaata tgaggggttg cctgtttctc tagtagaggc tcaggcatcg ggattacaaa
     9301 ttttatcgtc agatacagtg acgcaagaag tagatgtgac caaaaacatt agttacttac
     9361 ctatcaacga agagtctgtg ttgctatgga aagataaagt actgtcttta acatctgagg
     9421 aatgcaatcg ttttgaaata aataacagta tgacagatgg actctatgat atttgttatc
     9481 aagctagtaa attattgaat cgttatcaag aaatgtgtgt aataaaggag atatagatgc
     9541 agacaaagta tatttgtaga gtgacactag tgacattaag ttttatattt gctttctgtt
     9601 acttgttctg gactctcgat aattggaata atggttttct tatatctaat tatgttccgt
     9661 ctatatttat atgggtttgc tttctaatta tttttcaaat tactggtttt attttacaaa
     9721 aagttagtat atatgatttt tctgtatggt atctgatttt atcttatttt tttatgtttg
     9781 gattaatttt caatgagtat atggggtttc aaacaactct gctgtggagc cctagtaact
     9841 tctataataa tgaagaatta tttcattcat atatttttat aatttggatt ttgttttgtt
     9901 attctgtagg ctatttattt ttttatagtg atggaaaggt acattatcat tcagaagtac
     9961 aaaattatca ggaaaatgaa gagaaaattt tgtacaatgc gggtaggatt ttaacaggag
    10021 tgggctttat ttctagggta ataactgatt ctaaaacagt actagcagtt agagcggcga
    10081 atagctattc agcatattca gaggcagcta gttcaggaat aatagatgat ttaggagtac
    10141 ttatgcttcc tggtgtgttc tccttgtttt attcagataa gctgtcccga gttataaagc
    10201 gtactatttt ttgggtaatg ttgttttacc taattttgat aatgatccta acaggaagtc
    10261 gtaaaatcca ggtgttttca atcttggcgt tggttttagt atacacacaa tctttaggga
    10321 ttactttttc gaagaaaaga gtacttgtat ttttaatagt aactgtattt ctattaaatg
    10381 tattagttgt tattaggggg caccgtttcg acttgaatac tataggtata tacttatttg
    10441 attccttttc ttcattagat tttgtaaaga atatactagg ggaagtattt tcagagtcgg
    10501 gactgaccag cctaacagta gcttctgctg taactgttgt gcctagtagc attccatatg
    10561 aatatgggat gacatttcta cgcactatcc tatcaatttt tcctattgga tggttagttg
    10621 gtgatttttt tgataaagca tcagcgacgg ttgttattaa taaatttttg gggttacctg
    10681 taggctcttc ttttgtggaa gaattatttt ggaactttgg ttactatggt ggtgtttttt
    10741 ggagttttgt tttgggaata tttagtggat ggcgattaaa tttcagagct tttcaaacaa
    10801 gtaaaatctc aaaagttatt tatttttcgg taatttctca actattgctt ttagtgagaa
    10861 gtagttcaat agatgtttat cgtcctatta tgtatagttt gattatgata tttattttta
    10921 ggaggttgaa aaaatagtgg tgaaaaaaat tatgttacat ggtgcaacgg attatggttc
    10981 aagtaattac ggtgattatc tttacggtga gattgtctat gatttattag aatctaaagg
    11041 atatgaagtt tctttttata atccatcaga tttctttcaa atgtacttga aagaatatcg
    11101 ccaaaaacaa agttttacta aaaaacaagc agatgctatt ttgtatatcc cgggaggata
    11161 ttttggggaa gggcataatg cacgttttcg tgataattta atccaattta aacgattttt
    11221 acctttggga atttgggctt catattttaa aaagcctata ggagtattag gtattggtgc
    11281 agggcctaat aacgattctt tgatgaatta tggtataaag agaattatta atcatgctca
    11341 atttattaca gttcgtgatc gagaatcatt tgattctttg aagcatttgt cgccttcggc
    11401 tccagtgcat gaaacctttg atttaattat ttcaagtaaa ttaagagaag aaaaaacaga
    11461 gcagctgtgt caattgaaaa gagaagctaa agataagaag ataattcttg ttcactataa
    11521 tcattccaaa aaagctcttg aaaaatttgc ggaatcaatt agtctttttc tagaaaacaa
    11581 tcctaactat tatgttgtag taacttcgga ttccattcta ccttatgaag atgcttatta
    11641 tcaggaattt agaaaattag ttagaactga ggattgtttt caattcaagt atcattctcc
    11701 tgcagaaatg acatcattgt tgaaaatggt agatgtggtt ttaacttgta aattacatgt
    11761 tggggtagtg gcaacatgtt ttaataaatc tgtgattgcc attgcatgcc atccagaaaa
    11821 aacagcacgt tattatggag caattggaga gttacaacgt tgtgaatctt tatttgattc
    11881 aagtgttaat agtattgtaa agaaacttga aacttttcat ctaaaaccga taacaatacc
    11941 ttcagaattg gtgttgaaag cgagaagtag tttggactat ttagatcttt ttttggaagg
    12001 actagttcgt gaaagttgat agaatttcat ttataaaaaa tacaagttct ctctatattc
    12061 tgaatattgt taaattacta tttcctttat taacactccc gtatttgaca agggtgcttt
    12121 cgctagacgc gtatggaatg gttatttatg ttaaagcgtt aatagcttat gttcaactgg
    12181 tgattgattt tggtttcatg atatcagcta caaaaaatat tgtaaatgct tgtactactc
    12241 cctcaaagat tggaaggata gttggagata ctctagttga aaaaatattt ttatctatca
    12301 tttcgattct aatttacacc atattgatgt ggcaaatccc aataatgaga gagaatattc
    12361 ttttttcagt tttttatttg ttagctacag tgaccaatat ttttatcttt gactttttat
    12421 ttcgtggaat tgaaaagatg catgcagttg caattcctta tattatttct aaaactatca
    12481 ttacaatttt gacatttatt gtagtaaaag atgattcttc tattttatgg attcctatat
    12541 tggaaggaat tgggaattta gttgctgcag tagtttctta tagattcctt cattattatg
    12601 gaattaaatt atcattttct tatctgtctg tttgggttaa agatttaaag gaatcctcta
    12661 tttatttttt atccaatttt gcaactacta tttttggcgt ctttacgaca gtcatttcgg
    12721 gtttttattt acaaagtcaa gagatagcct tttgggggat agcaatgcaa ctgctttcag
    12781 cagcaaaatc attgtataat cctatagcga atagtttata tccgcatatg atacgtacta
    12841 aagatataca atcggttaag agtattaatc ggattatgtt tattcctatt atctttggag
    12901 ttttgatagt tttattcttt tcaaatcaaa ttctttctat aattggtggt gaaaaatata
    12961 ccgtttcagc agattttctt aagtacttat tacccgcttt tgttgctagt ttttattcta
    13021 tgatttacgg atggcctgtc ttaggagcta ttgataaagt gaaagaaact acaatgacaa
    13081 ctatattagc ttcgattgtc caaactttgg gattaggaat atttatcttg tctgataatt
    13141 ttagtttagt aacattagct atttgttcaa gtatgtctga ggtggtgtta tggattagcc
    13201 gttatctaat ttattttaag aaccgttcat tatttgttag gagtaagtaa atatatgaaa
    13261 aaagtagttg tagtatttgg aactcgtcca gaagccatca agatgtgtcc tttggtcaaa
    13321 gagttaagaa cacgtaagaa tattgaaaca ttagtttgcg ttacgggcca acaccgtcaa
    13381 atgttggatc aggtcttgga cacatttggg attattcccg attttgattt gtctattatg
    13441 aaagataaac aaactttatt tgatgtgacc attggcattt tggaaggaat gaaggctatt
    13501 ttagagtcag aaaaacctga tttggtgtta gttcatgggg atacaagtac gaccttcgct
    13561 agttcactgg cggcctttta tttacagatt ccaattggtc atgttgaagc tggtttgcgc
    13621 acttacgata tctattcacc atatcctgaa gagtttaatc gtcaagcagt tggggttttg
    13681 gctcagtatc attttacacc aacacaactt tcaaaagata atcttttaag agaaggaaaa
    13741 actccagaga gcatatttgt gacaggtaat acggcgattg atgctttaca aactacaatt
    13801 caagaggact atacgcatcc tgagttagaa tggataggag aaagcaggtt tattctaatt
    13861 acagctcatc gtcgtgaaaa tcttggtgaa ccgatgagac atatgtttag agcaattaga
    13921 aggattattg aagaatattc agatgtcaag gctatttatc ctatccatat gaatcctcgt
    13981 gttcgccaaa ttgctgagga agaactaagt ggctgtgaac gtatcaagat gatcgaacct
    14041 ttagaagtat tagattttca caatttttta tcaagaagtt atttaatttt aacagatagt
    14101 ggtggtattc aggaagaggc tccaagttta ggaaaacctg ttttggttat gagagataca
    14161 actgaacgtc cagagggaat tgaagcaggg actttgaaac ttgtaggtgc tgatgaaaat
    14221 aatatttata ggcattttaa agaattatta gaaaatgatt cagtttatca agcaatgagt
    14281 caagcttcaa atccatatgg agatggaacg gcttgtaaga aaattgcaga catactagaa
    14341 ggagaagtgt aatatatgtc acaatttaca ggaaaaactc tcctaattac aggagggaca
    14401 ggttcatttg ggaatgcggt tctcaagcgt tttttagaaa cagatgtctc agagattcgt
    14461 atattttcgc gagatgaaaa gaaacaagat gatatgcgtc atgagtttca ggtaaaagta
    14521 ccagaagtgg ctgggaaaat ccgtttttac cttggagatg tgcgtgactt agcttcggta
    14581 aaaaatgcta tgcatggtgt ggattatgtt tttcacgctg ctgctcttaa acaagtacct
    14641 tcttgtgaat ttttccctgt agaagcggta aaaactaaca ttttgggaac ggagaatgtc
    14701 ctcactgcgg ctatcgaagc tggtgtaaag caagttatct gtctttctac agataaggcg
    14761 gcttatcctg tcaatgctat gggaacatcc aaggctatga tggaaaagat tgctgttgct
    14821 aagtccagga cggtaaatcc tgagcataca aagatatgtg tgactcgcta tgggaatgtt
    14881 ctgtgtagcc gtggatctgt cgttcctctt tggattgagc aaattaagca aggaaatgct
    14941 cttacaatta ctgaacctag catgacacgt tttgtgatga cattggaaga agcagtagac
    15001 ttggttttat ttgcatttga agaagggaaa tctggagata tactagttca gaaagcacca
    15061 gcatgtacga ttgaagtgtt ggctaaggct gtatcagaaa tttttgcctc agaacaagat
    15121 attaagatta taggtattag acacggagaa aaaaggtatg aaacactatt aactaacgaa
    15181 gagtgcgcaa atgcaattga tttgggtgat ttttatagag ttcctagtga taatcgtaat
    15241 cttaactatg ataagtattt caaagatggt agtacgaata gaaatttgtt gacagaattc
    15301 aatagtaata ataccgattt gatggatgta gagcaagtta aaagaaagtt gctagaatta
    15361 gatgaaatac agacagcaat tcgtgatatg gtagcagacg aagagatgta aaatctttta
    15421 agatacatta aaattatcaa ggatatataa tgtatcatgt attgtcgaga gagttaacta
    15481 ttaaaacagc atataaaata aggagggggc atgattaaaa atattttaat cacaggagcg
    15541 aaaggatttg taggaaaaaa tcttatctgt actctggaag ctttgaaaga tggacgagat
    15601 aggactcgtc ctaatttaga gattggagag atttttcagt atgatcgtga tacagatccg
    15661 attttattag atgaatattg taagaaggcc gatttcgtat tccatttagc tggtgtcaat
    15721 cgtccacaga atcctgatga attcatggag ggaaattacg gtttttcaag tagattattg
    15781 gagattttag aaaagtatga aaacacttgt cctgttctac tctcaagttc tactcaagct
    15841 agtttagaag gccgattttc aaactctata tatggacaat ctaagctagc aggggaagaa
    15901 ctcttctttg aatatggaaa gaaaacggga gcacctgtct tagtttaccg tttcccgaat
    15961 ctttatggga agtggtgccg tcctaactac aattctgctg tagcaacttt ctgttataat
    16021 ctagctcacg atttacctat tcaagtaaat gatccaagtg tagaattgga gttgctgtat
    16081 attgatgatt tgatacaaga gtgtctaact gcattggaag gaaatcctca tcgttgtaat
    16141 ctagatggat tacaaatctt acctagccca tcaggaaact actgctacgt accaacgact
    16201 catcgtgcaa ccttaggaga gattgtctct ctattagaaa catttaaaaa acagcctgat
    16261 agtttagtta tgcctgaaat tcctcaggga tcgtttaaaa agaaattgta ttctacctac
    16321 ctatcttatt taccagtaga taagtttaag tttcctctaa aaatgaatat agatgaacga
    16381 ggtagtttta cggaattatt aaaaacagaa aatacgggtc aattttctgt taatatttct
    16441 aaacctggca ttaccaaagg gcaacattgg catcattcta agtgggaatt tttcatggtt
    16501 gtttctggtc gtgctttaat acaagagcgt aggatagggc tggatgaaaa cggtcaagag
    16561 tatcctattc tgaactttga agtgtcgggc gataagattg aagcaataca tatgataccg
    16621 ggctatgcac ataatattat taatctttct gatacagaaa atctaattac tgtcatgtgg
    16681 gctaatgagt catttgatcc tagacatcca gatacttttt ttgaacaagt ggagaaataa
    16741 atgaaaatta agacagatta tagtgatatt cactttaaag ataatggcaa acttaagtta
    16801 ttgattattg tgggaacacg tccagagatt atacgtctaa gtagtgttat cactaaatgt
    16861 cgaaagtatt ttgatgttat tttggcacat actggacaaa actatgatta caatttaaat
    16921 ggtattttct ttgataattt agggttagac actccggacg tatacatgga tgctgttgga
    16981 gatgatcttg gtgctactgt agggaatatt attaatactt catacaaatt gatgaatcaa
    17041 attaaaccag atgctttatt gattttaggg gatacaaatt cttgtttatc agctattgct
    17101 gccaagcgtt tacatattcc aatttttcat atggaggctg gcaatcgctg taaagatgag
    17161 tgcctaccgg aagagactaa tcgtcggatt gttgatgtta tttcagatgt taacttagca
    17221 tactctgaac atgcacgtaa gtatttacat gagtgtggtt tacctaaaga gcgcacatat
    17281 gtaactggtt ctcctatggc agaagtgtta cataaaaatt tatctgctat tgagtcttca
    17341 gatatccatg aacgtttggg attgaaaaaa ggaggttata tcttactttc agctcaccgt
    17401 gaggaaaata ttgatacaga taaaaatttt atttctctct ttacagcaat taatcaatta
    17461 gctgaaaagt ataatatgcc aatcttatat tcttgccatc ctagatcaaa gaaaaggcta
    17521 caagagagcg gttttaaact agataaacgt gtgattcagc atgagccact aggattccat
    17581 gactataatt gtttacagat gaatgcattt gttgtagtat ctgattcggg aactttaccg
    17641 gaagaaagta gtttctttac tagtcaaggt tatccttttc ccgctgtatg tattcgtaca
    17701 agtacagaac gtcctgagtc cttagataag gcaggattta ttttggcagg cattgatgaa
    17761 aattctcttc ttcaagcagt tgaaactgct gttagcttgg cacaagatga ggattttgga
    17821 ttaccggttc cggattatgt tgaggaaaat gtctctacta aagttgttaa gataatacag
    17881 agctatacag ggatagtgga taaaatagtt tggaggaaaa gctgaattgt atatttttaa
    17941 taaatcaaaa cgagatgatt aattcttagt agaacaagag taaaattgaa cgtatttgat
    18001 ggaaatgtct tacttgatag tcgagggata gccattctat cggatttttg gcttgttttt
    18061 gcgcttcatg tttgatagaa taaagggctc tttgtcaact gtagtgggtt gaagaaaagc
    18121 taagcttgag aaaggacaaa tttcgtcctt tcttttttga tgttcagagc gataaaaatc
    18181 cgttttttga agttttcaaa gtttcgaaag taaccgccca ataacgaagt ctattgaaaa
    18241 atctccagac tagagaactc atatatagtt cctaatctgg agatttctta tttgcacttt
    18301 tcttgtacaa ctttagtcca cggtaaatag gcctctaaaa cctctttgtt tacgagagtt
    18361 tcctcgtttg gaagacattc tagaagatag gatagatatt tctcgctatt tataatggat
    18421 tgtaataaga tatgaacaaa tcgattagga aaggaaaatt gatttataga aatattttag
    18481 cagtcgatgc gtactgttat agattcaacg cactataatt gatgacgttt agctgtttcc
    18541 aacaaactca taataatagc tcttgcttta gctccttcaa aactttgaga aaataaccac
    18601 cctcgctttt ttaaaaataa ccaccctcgc ttttttaaac tgagcttagg ctaaaagagt
    18661 ccactggact cttttactcc gtcccataac caatgattta atggcgcgtt cagctagatt
    18721 attggaaagg accagatgtc cgtcttttaa aatggtctta aaggtttctt catacttgag
    18781 gctgtattca attgcccttc ctagttttga acccgataaa actgactgac gacggcacca
    18841 agcaaagaag tcttccagta ggggttggag atgttcttga cgtttctgta gccgttcatc
    18901 agctggcaaa gcctcccagt ctctttccaa ggaaaataac tgatcacaat aggctaaacc
    18961 tttagctcct aaggatgatt tatctgcttg cttggggggc acttcaaaaa acttccttct
    19021 cacatgcgcc caacatccaa caagtgcagc ttcttccagt tgacgataag cttctagctg
    19081 ttcgcagttt accaagctta gcgtcgcctt actcctaaac cttggactgc tatcgcatag
    19141 gcagaactag aggactaaag tcctaagtta ctgccgcaac atgtcacaat gaacatagcc
    19201 agaataatct cctaggaatt cttgtactac tgaaccactt cgacactgat catggtggta
    19261 aagcgtaatc ccttgtttct ctgctttacc tgacaaaaaa gtccaatagt aggtcagatg
    19321 gctatcactc tctagaaccc gataggaggt ttcatccgca tgaagtaagg gctgagtcaa
    19381 tagtctctct cgcaagaggt tataaagggg ctttaggaat aggagctttc acaagcttat
    19441 ccagatgatt atcttttact cgttatggac aatgctatat ggcataaatc aagtacctta
    19501 aagattccga ctaatattgg ctttgcattt attcctccat acacaccaga gatgaacccc
    19561 attgaacaag tgtggaaaga gattcgtaaa cgtggattta agaataaagc ctttcgaact
    19621 ttggaagatg tcatgaatca acttcaagat gttatacaag gactggagaa ggaggtgata
    19681 aagtccatcg ttaatcggag atggactaga gtgctttttg aaagcagatg agtataaaaa
    19741 gaaagtcctc atttcaatag aaatcacgac tttctgatgg atttatagta aaatgaaata
    19801 ataacaggac aaatcgatca ggacagtaaa atcgatttct aacaatgttt tagaagcaga
    19861 ggtgtactat tctagtttca atctactata tttttggagt gatagaaaag cctttcatca
    19921 gccaatctac ttgttcaggt gcgagagctt tgacatcctt ttctgtactg ggccaagtca
    19981 gtctgccgtt ctcaaagcgt ttatatagta gccaaaatcc ttgaccatcc cagtaaagga
    20041 ctttaaagcg gtctttacgt ccaccacaaa agagaaagat ttgaccggag aaaggatcca
    20101 attcaaagtg ggttttaacg agataagcca gtgaatcgat tccttgtctc atatcagttt
    20161 tcccacacac gagatagacc tgccctaggc tagatagatg aattgtcata gagcaacacc
    20221 ttatccaaaa gctgttctat catttcgaga ttgagagatt gaaaaaaact tacttcaagc
    20281 ttgccaatac gaattttaag tagaatatca tttctctttt tagaatcaaa acgacgagat
    20341 tgtggaatct ctacaggaac aataggttgt ggcattaaaa tatcctccaa tatttacttt
    20401 actaatagta tacaggagga gctccatgaa tgatagatac cttgttatga cgcgcttacg
    20461 atattcatat tttttgcaaa gatgttgttt gaaaaataat tttcaaaaat tctgaaaatt
    20521 ctgttgacaa ctttctgaaa agagtctata atggagagaa agttttaaag gagaaaatga
    20581 tgaaaagttc aaaactattt gcccttgcgg gcgtgacatt attggcggcg actactttag
    20641 ctgcatgctc tggatcaggt tcaagcacta aaggtgagaa gacattctca tacatttatg
    20701 agacagaccc tgataacctc aactatttga caactgctaa ggctgcgaca gcaaatatta
    20761 ccagtaacgt ggttgatggt ttgctagaaa atgatcgcta cgggaacttt gtgccgtcta
    20821 tggctgagga ttggtctgta tccaaggatg gattgactta cacttatact atccgtaagg
    20881 atgcaaaatg gtatacttct gaaggtgaag aatacgcggc agtcaaagct caagac
//
