LOCUS       CR931712               22089 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain Colemore (serotype 40).
ACCESSION   CR931712
VERSION     CR931712.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22089)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22089)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Colemore"
                     /db_xref="taxon:1313"
     gene            <1..166
                     /gene="dexB"
                     /locus_tag="SPC40_0001"
     CDS             <1..166
                     /gene="dexB"
                     /locus_tag="SPC40_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34442.1"
                     /db_xref="GOA:Q4K241"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K241"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVP
                     WDAFCVEMTD"
     gene            complement(313..1707)
                     /gene="tnp"
                     /locus_tag="SPC40_0002"
                     /pseudo
     CDS             complement(join(313..447,447..1577,1576..1707))
                     /gene="tnp"
                     /locus_tag="SPC40_0002"
                     /note="member of homology group 17"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1202 transposase"
     misc_feature    complement(723..1223)
                     /gene="tnp"
                     /locus_tag="SPC40_0002"
                     /note="HMMPfam hit to PF00665, Integrase core domain,
                     score 1.1e-21"
                     /pseudo
     gene            1874..3328
                     /gene="wzg"
                     /locus_tag="SPC40_0003"
     CDS             1874..3328
                     /gene="wzg"
                     /locus_tag="SPC40_0003"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34444.1"
                     /db_xref="GOA:Q4JZ21"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ21"
                     /translation="MLIMSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNI
                     LAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGL
                     TNRLNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKLSQNT
                     DLTVDQSSSYLVAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKV
                     EAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPI
                     ADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVH
                     NDQEFSALHGKFHFPVGNVHLDSEQALSFVRERYSLADGDRDRGRNQQKVIVAILQKL
                     TSTEALKNYSTIIDSLQDSIQTNMPLETMIDLVNAQLESGGTYKVNSQDLKGTGRMDL
                     PSYAMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1874..1999
                     /gene="wzg"
                     /locus_tag="SPC40_0003"
                     /note="Signal peptide predicted for SPC1814 by SignalP 2.0
                     HMM (Signal peptide probability 0.991) with cleavage site
                     probability 0.537 between residues 42 and 43"
     misc_feature    2087..2434
                     /gene="wzg"
                     /locus_tag="SPC40_0003"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 3.9e-61"
     misc_feature    2612..3055
                     /gene="wzg"
                     /locus_tag="SPC40_0003"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 2e-69"
     gene            3330..4061
                     /gene="wzh"
                     /locus_tag="SPC40_0004"
     CDS             3330..4061
                     /gene="wzh"
                     /locus_tag="SPC40_0004"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34445.1"
                     /db_xref="GOA:Q4JZ20"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ20"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSCHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     misc_feature    3333..3941
                     /gene="wzh"
                     /locus_tag="SPC40_0004"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1.9e-38"
     gene            4070..4762
                     /gene="wzd"
                     /locus_tag="SPC40_0005"
     CDS             4070..4762
                     /gene="wzd"
                     /locus_tag="SPC40_0005"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34446.1"
                     /db_xref="GOA:Q4JZ19"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ19"
                     /translation="MQDQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGTYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVIVPIDTRIVSVSVNDRVPEEASRIANSLREVAAKKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGLGTSVIVLLLELLDTRVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     misc_feature    4088..4504
                     /gene="wzd"
                     /locus_tag="SPC40_0005"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 5.8e-51"
     misc_feature    4610..4687
                     /gene="wzd"
                     /locus_tag="SPC40_0005"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4772..5455
                     /gene="wze"
                     /locus_tag="SPC40_0006"
     CDS             4772..5455
                     /gene="wze"
                     /locus_tag="SPC40_0006"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34447.1"
                     /db_xref="GOA:Q4JZ18"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ18"
                     /translation="MPTLEIAQKKLEFIKKAEEHYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDAQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            5471..6838
                     /gene="wchA"
                     /locus_tag="SPC40_0007"
     CDS             5471..6838
                     /gene="wchA"
                     /locus_tag="SPC40_0007"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34448.1"
                     /db_xref="GOA:Q4JZ17"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ17"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETEVERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAIGVLNFFIVERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFINLPGESYDIGEIISRFETMG
                     IDVTVNLNAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHLISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKINNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPK
                     QKRRLSFKPGITGLWQVSGRSKITDFDAVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     misc_feature    6254..6835
                     /gene="wchA"
                     /locus_tag="SPC40_0007"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 2.3e-145"
     gene            6869..8050
                     /gene="wchF"
                     /locus_tag="SPC40_0008"
     CDS             6869..8050
                     /gene="wchF"
                     /locus_tag="SPC40_0008"
                     /note="member of homology group 15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34449.1"
                     /db_xref="GOA:Q4JZ16"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ16"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKAIQYYVACMR
                     ENSAKSGTTEDVFEHNGAICYNVDVPNIGPARAIAYDIAAINRAIEIAKENKDENPIF
                     YILACRIGPFIHGIKKRIQAIGGTLLVNPDGHEWLREKWSLPVRKYWKYSERLMVKYA
                     DLLVCDSKNIEQYIQEDYKQFQPKTTYIAYGTDTTPSILKFEDTKVRNWYQEKGISEN
                     GYYLVVGRFVPENNYEAMIREFIKSQSKKDFVLITNVEQNKFYDKLLRETGFDQDPRI
                     KFVGTVYDQELLKYIRENAFAYLHGHEVGGTNPSLLEALGSTKLNLLLDVGFNREVGE
                     DGAIYWQKDELSRVIEYVETINQATIANLNFKSTQRILSDFTWEKIVADYEGVFCFAK
                     S"
     misc_feature    7484..7978
                     /gene="wchF"
                     /locus_tag="SPC40_0008"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 0.0035"
     gene            8007..8897
                     /gene="wcwI"
                     /locus_tag="SPC40_0009"
     CDS             8007..8897
                     /gene="wcwI"
                     /locus_tag="SPC40_0009"
                     /note="member of homology group 99"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34450.1"
                     /db_xref="GOA:Q4JZ15"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ15"
                     /translation="MWQIMKEYFVLRRVSVPNLYAVVVLYNSLLSEAKILKTLNTLNC
                     KELNLIVVDNSDRKEIQLKNKNFSTENNITLVNMNGNQGLSKAYNKVLELLKGRIGYV
                     VWLDDDTEISVEYLTKLLYASRGNYDIILPIIQDTHGKIVSPNSRGLLSNKPIKSYKD
                     GKKLEKFNAINSCTAVNLDIYEEYRYDERLFLDEIDHSFFYDHRNKNLKIELINTIVI
                     QNFSQRADNLNFDTAWSRLKIRIRDLIVAYKIRGGIFMGLVAVLKSILLGLQLYLKIK
                     DLRIVIYSFTSALCIFFRKT"
     misc_feature    8064..8561
                     /gene="wcwI"
                     /locus_tag="SPC40_0009"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 4.9e-11"
     gene            8894..10090
                     /gene="wcwL"
                     /locus_tag="SPC40_0010"
     CDS             8894..10090
                     /gene="wcwL"
                     /locus_tag="SPC40_0010"
                     /note="member of homology group 100"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34451.1"
                     /db_xref="GOA:Q4JZ14"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ14"
                     /translation="MKMKILYFMNNTDHGGAALALLDLVTQINENYPEYELIVVTGKK
                     NNLNVKLTEIGIENYFFPFRNFISSYKKPAILWTILYKIRHYIGNRMALKKIEKKIDL
                     KKIDIIHSNLNRIDIGAILAKKHSIPHLCHIREHLDVWYFYNKLDHRKFEYDFKVLTT
                     EKNYIFYMCSFSTKYIAISNSVAMDWCKKGLSQSSIVKVYDGIKLPQVFGDKKWFRNK
                     KINIVFVGGYDIKKGQELFLSYFLKLPKEIQMQYTLTFYGSGKSKYIKKLQKMSQHLC
                     SDQVKFHSYIDNLTELLPNYDIGINFSTMEGFGRVTVEYLANGLCVVANKSGASPELI
                     TEEVGFLIDKDNQDEFIQLFTKLSIEKNKIRQMGNKAVNQAQKFSINQHTREIINVYQ
                     EMRNKQ"
     misc_feature    9509..10015
                     /gene="wcwL"
                     /locus_tag="SPC40_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 3.2e-19"
     gene            10087..11094
                     /gene="wcwK"
                     /locus_tag="SPC40_0011"
     CDS             10087..11094
                     /gene="wcwK"
                     /locus_tag="SPC40_0011"
                     /note="member of homology group 64"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34452.1"
                     /db_xref="GOA:Q4JZ13"
                     /db_xref="UniProtKB/Swiss-Prot:Q4JZ13"
                     /translation="MKNMEQIDFVVTWVNNKDVDWCKRKSEFEKEYNIFQDLNSEERY
                     REWGFMKYWFRAVEKYAPWVNKIYFITEGHVPNWLDVNHPKLVHVKHEDYIEKQFLPT
                     FNSNVIEMNLIHLKDLSEKFVLFNDDTFINDFVKQSDFFENNLPKDTGIFSPLIPREN
                     SLTPIVLNNMEIINKYFSKKKILEQNFSKFFNIKYGKHLLKNICLLPWSDLLGFYNSH
                     IPVSYCKSNFLEVYEKEYDIFNLTFKNKFRNKNEINHWLIRYWQLSSGNFIPRNINFG
                     KNYAISNDPTDIINELKFSKYKIICINDGESIDSFDEVKDLMIDAFEKKFPEKSSFEK
                     K"
     gene            11091..11951
                     /gene="wcxU"
                     /locus_tag="SPC40_0012"
     CDS             11091..11951
                     /gene="wcxU"
                     /locus_tag="SPC40_0012"
                     /note="member of homology group 101"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34453.1"
                     /db_xref="GOA:Q4JZ12"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ12"
                     /translation="MRQIRMNLEDLVLIILNYNSAKDTLRCLEILRSFNMNFKIIVVD
                     NNSTDNSIELLKNIEDPQTTFLISDENRGYGAGNNIGIHFAENNFSSNIIGIINPDIV
                     IPNQEVIISMYNVLKNSDFAMVGGSVIDNEGNYRLLNSSWNLPSFKSVVLERFLIYNR
                     HKVPYCLNMYNDETAIVDCVAGCFFMIKADVMKEIGYFDENVFLYNEENILGMKLREK
                     GFQSIILTKQFYYHLHDFEKDKVELSLSKKCKRDWVKFQSRKYFTEKYYSKFLGFLLF
                     LLKYLICFKL"
     misc_feature    11124..11678
                     /gene="wcxU"
                     /locus_tag="SPC40_0012"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1.6e-20"
     gene            12003..13235
                     /gene="wzy"
                     /locus_tag="SPC40_0013"
     CDS             12003..13235
                     /gene="wzy"
                     /locus_tag="SPC40_0013"
                     /note="member of homology group 65"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34454.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ11"
                     /translation="MKKSSTLHIGLILFLIVLSKNFFNLVPNIALFSDFNLMIIIIIM
                     TVVNIKYYNRSTKYQYRWYIIFTLIFVLYSAINEKLLYGQPFLLGLLPQRQFFLCLMT
                     YFPLRKYFQEQNISLKKLYVGIMNLGSISSLIYILQKIVILYGGTQFVNVMYSFAGYF
                     SGYRLYVGSSLIILATLISTAYFLETLKLKYLCHLILGWFTQIWITQGRIEMIVLLIS
                     TIVCIIVQGRLTRKKIIYWLLTILGLWMITLTPIFENIVGAILKVDGAGRGSDSLTIR
                     AIGRQLYWDQLNETTSKLLFGTGYPNYNYALAFQRTGFSSNIFLTDNGFMTHIYIYGI
                     VGSSIMGLLFLKYLKNSIKYARQSADMIPLMYIISLLIVAYNIILWYWNADGTFILVI
                     MICALEHGEQLLHQRNGV"
     gene            13240..15192
                     /gene="rbsF"
                     /locus_tag="SPC40_0014"
     CDS             13240..15192
                     /gene="rbsF"
                     /locus_tag="SPC40_0014"
                     /note="member of homology group 49"
                     /codon_start=1
                     /transl_table=11
                     /product="putative phosphotransferase"
                     /protein_id="CAI34455.1"
                     /db_xref="GOA:Q4JZ10"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006439"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ10"
                     /translation="MNLNKEVRWKDKQYIAFDFFDTTIHRNCHPEVILFEWSKKISIY
                     FSFKISATEIYSIRKKSEIHEKQEKQLEEIKYERLLQLVFYTILSRLKSDVTDYNLED
                     FLIYARTCEEEIELRHISIDTDTINFIEFLKQNGKKIILISDFYSDKKLIEKLMVSLG
                     IRDYFSKIFISSEIGLRKSSGNLYEYVINELSCKPINLLMIGDNIYSDVKVPKKLGID
                     SYHKSYSDSHVTVSPNDIVKAMNNVISQACTESLFNLYIPEILYFISKLYKELSVNKA
                     SDILFCAREGFFIKKLFDLYQKKMNLKLINSHYFYVSRKSTLYPSFKNIEDEDFEVIF
                     RQFPEITLENFLINLNFSNNDINNISKQTEIKQTDKVSDKSIINKLKQNKLFKDVYDL
                     NCKEEKYSFREYLKSVGVENDNSTINMVDIGWKGTIQDNIQKAFPSLNIKGYYMGLNF
                     QRYSTRNSMNKTGILFTDDPQKTKFFNLFNYKYLFYERIFVADHGPTVRYEFMNGVGV
                     PTLDTDENHIEIYRFSEEFQITFFNTFEKILDLFNESLVTPDELFNEIANLSLKKHCI
                     YLPRLSVSIKKLDRAAKENFGIIKSTNRNSDNKVRNFWKNRDFLFLDYIYKAYGKNRL
                     LNPILDIYGYFVYLIKTLQIKIVGDI"
     misc_feature    13273..13914
                     /gene="rbsF"
                     /locus_tag="SPC40_0014"
                     /note="HMMPfam hit to PF00702, haloacid dehalogenase-like
                     hydrolase, score 1.8e-07"
     gene            15189..16649
                     /gene="wzx"
                     /locus_tag="SPC40_0015"
     CDS             15189..16649
                     /gene="wzx"
                     /locus_tag="SPC40_0015"
                     /note="member of homology group 47"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34456.1"
                     /db_xref="GOA:Q4JZ09"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ09"
                     /translation="MMSMKEKSINKNAILNIILTLTNIVFPLITFPYISRILNPSGIG
                     AISFFSSIGSYGVLVASLGISTYGIRVIAKDRYHKDKITKIFQELIVINSVMSIIVTF
                     FLVLMSFRLEQLSSEKGLLIITCITILSSPFNLNWFYSGIEEYSYITKRSIFFKLVSL
                     ILTFLFVKSKDDYILYAVITLFSTLASNFINILESRKYINFNLRRDLEFRYHLKPMWY
                     LFASLLAVNIYINLDSVMLGIINGNDAVGIYSIASKVKWILLSVVTSVSSVLLPRLSF
                     YSNKYDETKFNNILRKSSTIIFMISIPLTIFFMIKAKESILLLGGEQYIQAVLAMQIL
                     MPILVISGFSNITGNQILIPTGNEKYFMRAVSIGAIVNLCLNLLLMPILGIIGGAIAT
                     LCAESVQMIIQFYFSRNKLMGNISLNSIKKIAYSSIFAGILLIVIQNIIENFNSFLNL
                     AASSFLYFGVYFFLLVLFKESTIKKFLNQIFYKDIS"
     misc_feature    15213..16022
                     /gene="wzx"
                     /locus_tag="SPC40_0015"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.3e-61"
     gene            16791..17693
                     /gene="rmlA"
                     /locus_tag="SPC40_0016"
     CDS             16791..17693
                     /gene="rmlA"
                     /locus_tag="SPC40_0016"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI34457.1"
                     /db_xref="GOA:Q4JZ08"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ08"
                     /translation="MKTNLKRRDYSMKGIILAGGSGTRLYPLTRAASKQLMPVYDKPM
                     IYYPLSTLMLAGIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFI
                     IGEEFISDDSVALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFD
                     QDMKAISIEEKPEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDR
                     GDLSVELMGRGFAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISRED
                     VLALAQPLKKNEYGQYLLRLIGEA"
     misc_feature    16827..17543
                     /gene="rmlA"
                     /locus_tag="SPC40_0016"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 1.1e-119"
     gene            17694..18290
                     /gene="rmlC"
                     /locus_tag="SPC40_0017"
     CDS             17694..18290
                     /gene="rmlC"
                     /locus_tag="SPC40_0017"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI34458.1"
                     /db_xref="GOA:Q4JZ07"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ07"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPASFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     misc_feature    17730..18260
                     /gene="rmlC"
                     /locus_tag="SPC40_0017"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 8.1e-16"
     gene            18300..19349
                     /gene="rmlB"
                     /locus_tag="SPC40_0018"
     CDS             18300..19349
                     /gene="rmlB"
                     /locus_tag="SPC40_0018"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI34459.1"
                     /db_xref="GOA:O54546"
                     /db_xref="HSSP:1KEP"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:O54546"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    18315..19271
                     /gene="rmlB"
                     /locus_tag="SPC40_0018"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00012"
     misc_feature    18318..19058
                     /gene="rmlB"
                     /locus_tag="SPC40_0018"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 5.4e-77"
     misc_feature    18321..19133
                     /gene="rmlB"
                     /locus_tag="SPC40_0018"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/iso, score 1.4e-05"
     gene            19415..20266
                     /gene="rmlD"
                     /locus_tag="SPC40_0019"
     CDS             19415..20266
                     /gene="rmlD"
                     /locus_tag="SPC40_0019"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI34460.1"
                     /db_xref="GOA:Q9AH81"
                     /db_xref="HSSP:1N2S"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q9AH81"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAKMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    19415..20263
                     /gene="rmlD"
                     /locus_tag="SPC40_0019"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 4.3e-146"
     misc_feature    19418..20047
                     /gene="rmlD"
                     /locus_tag="SPC40_0019"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 2e-18"
     misc_feature    19418..20059
                     /gene="rmlD"
                     /locus_tag="SPC40_0019"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00011"
     misc_feature    19421..20149
                     /gene="rmlD"
                     /locus_tag="SPC40_0019"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 3.6e-08"
     gene            20413..21412
                     /gene="glf"
                     /locus_tag="SPC40_0020"
                     /pseudo
     CDS             join(20413..20832,20820..20933,20909..21412)
                     /gene="glf"
                     /locus_tag="SPC40_0020"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
     misc_feature    join(20749..20820,20832..20909,20933..21352)
                     /gene="glf"
                     /locus_tag="SPC40_0020"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 1.5e-101"
                     /pseudo
     gene            21730..>22089
                     /gene="aliA"
                     /locus_tag="SPC40_0021"
     CDS             21730..>22089
                     /gene="aliA"
                     /locus_tag="SPC40_0021"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34462.1"
                     /db_xref="GOA:Q4JZ60"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ60"
                     /translation="MMKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    21730..21816
                     /gene="aliA"
                     /locus_tag="SPC40_0021"
                     /note="Signal peptide predicted for SPC1832 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    21976..22044
                     /gene="aliA"
                     /locus_tag="SPC40_0021"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     7406 a   3047 c   4302 g   7334 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
      121 aatcttagtt ccatgggatg ctttctgtgt ggaaatgact gactagaatg agcaaacctc
      181 aagtttttga agcttgaggt tttttactat agtggattga aactagaata gtgcacctct
      241 gcttctaaaa cattgttaga aatcgatttg actgtcccga tcgatttgtc ctattcttat
      301 ttcattttgc tatacttgta gttgaggaga attaagctcc tcactagtaa actcttcata
      361 atccttttta tttttatgaa gatattgttt gaaagatgtg agtttccacg gatgggtttg
      421 tggagggata tacttgcgtc tttctttttt tgttctggtt cttgttcaaa gtttttcgaa
      481 tagagttcat gatttagtag ctcctttgtg tgatagattt tgtcagcgat attgaggtag
      541 atgtctccgt caaatgcttt tataactaat gctttcgtct ttctgatgaa atagacttct
      601 tttccttgtt cggtagggat atagtaacga ttttggaatc ggatatggtg tccactatcg
      661 acgactctct ccgccagtct agccagaatg agattccttt cagaggggtt aggaacctcc
      721 tcgaagacag agagttttgt cttgtttcca aactgttcat taaaggtttg aatgtaggaa
      781 agcaggaagg tattggcttc ttccaaggta tgaatattgt tttgttccag ttcgataggt
      841 aggcgagatt gtagtgtctg attgagtctt tcgactctcc ctttagcttg agggatagag
      901 gttgtctcaa ggagaatccc tagttggtga caggcgcatc caaactgtgt atgggtatcg
      961 tcctccattt tcttagagtt ggaggcttga taggtaaaga ccgttctctt atctgtttta
     1021 atttgaaggg gaatgccgtg attggctaag atttgttcga ggacatgata gtaagcattc
     1081 aagttctctt gtttatcaaa ataagcgcct aggatattgc cagaagcatc atcaatggct
     1141 aagtgtaagt tagatgtttg ggctccaaac taggcatgag gactggcatc catttgaatg
     1201 agttcaccag caaatttctt tctgggtcta ctaggatgta cttttttagg gtcttcaagg
     1261 aagttttcag ccgtcggtaa gattggattg tctaggggtt gattcaggtt cagtttagct
     1321 tgttttctta ctctcttctt tgtctttcta tgggacttag gcgacaggat atttttctta
     1381 tagagtattt ttctaacagt agtatcagag agctgaattc cttcttcttc agctagcaat
     1441 tcacagaaat gaaggacatt tggtttatat gtttcatagg agaggtattt ttttaggaga
     1501 cgttctttga tttcatcagg gattgcatgt tttggttttc gatttctgtt tccgtgtctg
     1561 aaggcttctt tgtcctttca gttgataggc tagtagcaga cgattgattt gtctttcaga
     1621 aagattgagc tcgacacagg ctcgtttctt tgttttcttt ccttgggcta tagcttttat
     1681 cacaagatat tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta
     1741 ccaaatggga cattttcacg ttcgatttac taaagacatt atcacattcg aattacacaa
     1801 gatgcagata gtgaaaaaag gtgtagacat taccgtaaaa aagtgatata atcataagat
     1861 gttcaatgta taggtgttaa tcatgagtag acgttttaaa aaatcaggtt cacagaaagt
     1921 gaagcgaagt gttaatatag ttttgctgac tatttattta ttgttagttt gttttttatt
     1981 gttcttaatc tttaagtaca atatccttgc ttttagatat cttaatctag tggtaactgc
     2041 gttagtctta ctagtagcct tggtagggct actcttgatt atctataaaa aagctgaaaa
     2101 atttactatt tttctgttgg tgttctctat ccttgtcagc tcagtgtcgc tctttgcagt
     2161 acagcagttt gttggactga ccaatcgttt aaatgcgact tctaattact cagaatattc
     2221 gctcagtgtc gctgttttag cagatagtga gatcgaaaat gttacgcaac tgacgagtgt
     2281 gacagcaccg actgggactg ataatgaaaa tattcaaaaa ctactagctg atatcaagtt
     2341 aagtcagaat accgatttga cagtcgacca gagttcgtct tacttggttg cttacaagag
     2401 tttgattgca ggggagacta aggccattgt cctaaatagt gtctttgaaa atatcatcga
     2461 gtcagagtat ccagactacg catcgaagat aaagaagatt tataccaagg gatttactaa
     2521 aaaagtagaa gctcctaaga cgtctaagaa tcagtctttc aatatctatg ttagtggaat
     2581 tgacacctat ggtcctatta gttcggtgtc gcgatcagat gtcaatatcc tgatgactgt
     2641 caatcgtgat accaagaaaa tcctcttgac cacaacgcca cgtgatgcct atgtaccaat
     2701 cgcagatggt ggaaataatc aaaaagataa attaacccat gcgggcattt atggagttga
     2761 ttcgtccatt cacaccttag aaaatctcta tggagtggat atcaattact atgtgcgatt
     2821 gaacttcact tctttcttga aaatgattga cttattggga ggggtagatg ttcataatga
     2881 tcaagagttt tcagctctac atgggaagtt ccatttccca gtagggaatg tccacctaga
     2941 ctctgagcag gctctaagtt ttgtacgtga acgctactca ctagccgatg gagaccgtga
     3001 ccgtggtcgc aaccaacaaa aggtgattgt ggctatcctt caaaaattaa cgtcaaccga
     3061 agcactgaaa aattatagta cgatcattga tagcttgcaa gattctatcc aaacaaatat
     3121 gccacttgag accatgatag atttggtcaa tgctcagtta gaaagtggtg gaacttacaa
     3181 agtgaattcg caagacttga aaggtacagg tcggatggat cttccttctt atgcaatgcc
     3241 agacagtaac ctctatgtga tggaaataga tgatagtagt ttagctgtag ttaaagcagc
     3301 tatacaggat gtgatggagg gtagatgaaa tgatagacat ccattcgcat atcgtttttg
     3361 atgtagatga cggtcccaag tcaagagagg aaagcaaggc tctcttggca gaatcctaca
     3421 ggcagggggt gcgaaccatt gtctctacct ctcaccgtcg caagggcatg tttgaaactc
     3481 cggaagagaa gatagcagaa aactttcttc aggttcggga aattgcaaaa gaagtagcag
     3541 atgatttagt cattgcttat ggtgcagaga tatactatac tctggatgct ctagaaaagc
     3601 tagaaaaaaa agaaattcct acccttaatg atagtcgtta tgccttgatt gagtttagca
     3661 tgcatacttc ctatcgtcag attcatacgg gattgagcaa tattttgatg ttgggaatca
     3721 caccagtaat tgctcatatt gaacgttatg atgctttaga gaataacgaa aaacgtgttc
     3781 gtgaactgat tgatatgggg tgctatactc agataaatag ttgtcatgtt tcaaaaccta
     3841 agttctttgg tgaaaaatat aaattcatga aaaagagagc tcggtatttt ttggaacgtg
     3901 atttagttca tgtagttgca agtgacatgc acaatttaga cagtagacct ccatatatgc
     3961 aacaggcata tgatatcatt gctaagaaat atggagcgaa aaaagcgaaa gaactttttg
     4021 tagataatcc cagaaaaatt ataatggatc aattaattta ggagaaaata tgcaagatca
     4081 aaacactttg gaaatcgatg tattgcagct attcagagct ttatggaaaa gaaagttggt
     4141 cattttatta gtggcaatta taacttcttc agttgctttt gcctacagta cttttgttat
     4201 caaacctgag tttactagta cgactcggat ttatgtagtt aaccgtaatc aggaagagaa
     4261 gtctggttta accaatcaag acttgcaggc aggaacttat ctggtaaaag actaccgtga
     4321 aattatccta tcgcaggatg ttttggagga agttatttct gatttgaaac tagatttgac
     4381 gccaaaaggt ttggctaata aaattaaagt aatagtacca attgataccc gtattgtctc
     4441 tgtttcagtt aatgatcgag ttcctgaaga agcaagccgt atcgctaact ctttgagaga
     4501 agtagctgct aaaaaaatta tcagtattac tcgtgtttct gatgtgacaa cactggagga
     4561 ggcaagaccg gcgatatcac cgtcttcgcc aaatattaaa cgcaatacac taattggttt
     4621 tttggcaggg gggcttggaa ctagtgttat agttcttctt cttgaacttt tggacactcg
     4681 tgtgaaacgt ccagaagata tcgaagatac actgcagatg acacttttgg gagttgtacc
     4741 aaacttgagt aagttgaaat aggagagagg aatgccgaca ttagaaatag cacaaaaaaa
     4801 actggagttc attaagaagg cagaagaaca ttacaatgcc ttgtgtacaa atatacagtt
     4861 gagcggagat aaactaaaag taatttccgt tacttctgtt aaccctgggg aaggaaaaac
     4921 aactacttcc gtaaatatag caaggtcgtt tgcgcgtgca ggctataaaa ctcttttgat
     4981 cgatggcgat actcgaaatt cagttatgtc aggatttttt aaatctcgtg aaaaaattac
     5041 agggctaaca gaatttttat ctgggacagc tgatttatct cacggtttat gtgatacaaa
     5101 tattgaaaat ttatttgtag ttcaatcggg atctgtatca ccaaacccta cagccttgtt
     5161 acagagtaaa aattttaatg atatgattga aacattgcgt aaatattttg attatatcat
     5221 tgttgataca gcacctattg gaattgttat tgatgcggca attatcactc aaaagtgtga
     5281 tgcgtccatc ttggtaacag caaccggtga ggtgaataaa cgtgatgccc aaaaagctaa
     5341 acaacaatta gaacaaacag ggaaactgtt cctaggagtt gttttaaata aattggatat
     5401 ctcggttgat aagtatgggg tatacggttc ctatggaaat tatggtaaaa aataacttag
     5461 gaaagatttt atggatgaaa aaggattgaa aatttttctg gcagtattac agagtattat
     5521 tgtcatttta ttggtttatt ttcttagctt tgttagagag acagaagttg aacgttcttc
     5581 gatggttata ctataccttc tccacttttt tgtattctat tttagttcct atggtaacaa
     5641 tttttttaaa agagggtacc tagttgagtt taatagtacc ataagatata tttttttctt
     5701 tgcaatagct ataggtgtat taaacttttt tatagtggaa cggtttagta tctctagaag
     5761 aggaatggta tacttcttaa ctttagaagg aatatcctta tacttgttaa atttcttagt
     5821 aaagaaatat tggaagcatg tgttttttaa tctaaaaaat agcaagaaaa ttttactgtt
     5881 aacagtaacg aaaaatatgg aaaaagttct tgataaattg ctagaatctg atgaactttc
     5941 atggaaattg gtagcagtaa gtgttttgga taaatctgat tttcaacatg ataaaatacc
     6001 tgtaattgaa aaggaaaaaa ttattgaatt tgcaacgcat gaagttgtgg atgaggtgtt
     6061 tatcaatctt ccaggagaga gctacgatat tggagaaatt atctctaggt ttgagacaat
     6121 ggggatagat gtaactgtaa atcttaatgc atttgataag aatttgggtc gcaataaaca
     6181 aattcatgag atggtaggat tgaatgtagt cactttctct acaaattttt ataaaactag
     6241 tcatttgatt tcaaagagaa ttctcgatat ttgtggtgcc actattggcc ttattctttt
     6301 tgctatagct agtctagttt tagttccatt gattcgtaaa gatggcggac cagctatttt
     6361 tgctcaaact cgtataggga aaaatggtcg acattttacc ttttataaat tccgttcaat
     6421 gcggatcgat gctgaagcta tcaaagaaca gttgatggat caaaatacga tgcaaggtgg
     6481 tatgtttaag ataaacaatg atcctcgtgt tacaaaaatt ggtcgcttta ttcgtaaaac
     6541 cagtttggat gaattgccac aattttggaa tgtctttatt ggagatatga gtttggttgg
     6601 gacgcgtcca ccgacagtag acgaatatga tcagtatact ccaaaacaga aacgtcgact
     6661 cagctttaag cctggtatta caggcttatg gcaggttagt gggcgtagta aaataaccga
     6721 ttttgatgct gttgtaaaat tagatgtggc ttatattgat aattggacaa tctggaaaga
     6781 tattgaaatt ttgcttaaaa ctgttaaagt tgtatttatg agagatggag cgaagtaatt
     6841 tctgtatatc catcatatta ggagagaaat gaaaaagtca gtttatatca ttggttcaaa
     6901 aggaattcct gctaagtatg gaggatttga aacttttgtt gaaaaattaa cagccttcca
     6961 acaagataag gctatccaat attatgtggc ttgtatgcgt gaaaactctg caaaatcagg
     7021 gactactgag gatgtttttg aacataatgg tgctatctgt tataacgtcg atgttcctaa
     7081 tattggtcca gcgcgagcta tagcgtatga tatcgctgca attaacagag ctattgaaat
     7141 tgccaaagaa aataaggatg aaaatccaat cttctatatt ttagcttgtc gaattggtcc
     7201 gttcatccat ggaattaaga aaagaattca agcaataggt gggactcttc tggttaatcc
     7261 ggatggtcat gagtggctac gagaaaaatg gagtttacct gttcgcaaat attggaaata
     7321 ctctgaaaga cttatggtca aatatgcaga tttattggtt tgtgacagta aaaatatcga
     7381 acagtatatc caagaagatt ataaacagtt ccaacctaag accacctata tcgcttatgg
     7441 gaccgataca actccctcaa tcttgaaatt tgaagatact aaagtccgaa attggtatca
     7501 agagaaggga attagtgaaa acggttatta tttagtggtg ggacgatttg tccctgagaa
     7561 taactatgaa gctatgattc gtgaatttat caaatcccag tctaaaaagg attttgtcct
     7621 cattacaaat gtggaacaaa ataaatttta cgacaagttg cttcgggaaa caggttttga
     7681 ccaagaccca agaatcaaat ttgttggtac tgtttatgat caggaattgt taaaatatat
     7741 tcgagaaaat gcctttgcat atttacatgg tcatgaggtg gggggtacaa atccatcact
     7801 tttagaggct ttaggatcaa caaagttaaa tttgttgctt gatgttggtt ttaaccgtga
     7861 agttggtgag gatggagcta tttattggca aaaagatgaa ctttcacgag tcatcgaata
     7921 tgtggaaacg ataaatcaag caactatcgc aaacttaaat tttaaatcaa cccaaagaat
     7981 cctctcagat ttcacatggg aaaaaattgt ggcagattat gaaggagtat tttgttttgc
     8041 gaagagttag tgtgcccaat ttatatgcag tagtagtttt atacaatagt ttattatcag
     8101 aagcaaaaat tttaaaaacc ttaaatacat taaattgtaa agaattaaac ttaattgtag
     8161 tagacaatag tgataggaaa gaaatacagt taaaaaataa gaacttttcc actgaaaata
     8221 atataacatt ggtgaatatg aatggaaatc agggattatc taaagcttat aataaagtcc
     8281 tagaattatt aaagggtaga ataggttatg tggtttggtt agatgatgat actgagatta
     8341 gtgtagaata tttaacaaaa ttattgtatg catcaagagg taattacgac attattttgc
     8401 ctattattca agatacccat ggtaaaattg tttctccaaa ttctcgtggt ttactttcaa
     8461 ataaaccgat taaaagttac aaagatggaa aaaaacttga aaaatttaac gcaataaata
     8521 gttgtacagc tgtcaattta gacatttatg aagaatatag atatgatgaa cgacttttct
     8581 tggatgaaat tgatcattcg tttttctatg accacagaaa taaaaattta aagatcgaat
     8641 taattaatac aatagttatt caaaattttt ctcaaagggc tgataattta aattttgata
     8701 ctgcatggag tagattgaaa attagaattc gggatttgat agtggcttat aaaattagag
     8761 gtgggatttt tatgggtctt gtagctgttt taaaaagtat cctacttgga ctccagttat
     8821 acttgaaaat taaggatttg cgtatagtta tctatagttt cacatctgct ttatgtattt
     8881 tttttagaaa gacttgaaaa tgaagatttt atattttatg aataatacag atcatggtgg
     8941 ggctgcttta gcattattag atttagttac tcagataaat gagaattatc ctgagtatga
     9001 acttattgtt gtaacaggaa aaaaaaataa tttaaatgtt aagttaacag aaattggtat
     9061 tgaaaattac ttttttccat ttagaaattt tattagttca tataaaaagc ctgcaatact
     9121 atggacgatt ttatataaaa ttcgtcatta tatcggaaat cgaatggctc taaaaaaaat
     9181 agaaaaaaaa attgatttga aaaaaatcga tattattcat tctaatttaa atagaatcga
     9241 tataggagca atattagcca aaaagcacag tataccccat ttatgtcata taagagagca
     9301 tttggatgta tggtattttt ataataaatt agatcataga aagtttgagt atgactttaa
     9361 ggtcttgact acggaaaaaa attatatttt ttatatgtgt tctttttcaa cgaaatatat
     9421 tgcaatctct aactctgtag ctatggattg gtgtaaaaaa ggactatctc agtcatctat
     9481 tgttaaagtt tacgacggta tcaagttacc tcaggtattt ggtgataaga aatggtttag
     9541 aaataaaaaa ataaatattg tatttgttgg tggttacgat attaaaaaag gtcaggagtt
     9601 gtttttaagc tattttttaa aattaccaaa agaaatacaa atgcaatata ctttgacttt
     9661 ctatggaagt ggaaaatcta agtatataaa gaaattacaa aagatgtctc aacatctatg
     9721 ttctgatcaa gttaaatttc atagttatat agataatctt acagaattac taccaaatta
     9781 tgatattggg attaattttt caacaatgga aggttttgga agagtgactg ttgaatattt
     9841 agcgaacggt ctttgtgttg ttgcaaataa aagtggagct agtccagaat taataacaga
     9901 agaagttgga tttttaatcg acaaggataa tcaggatgaa tttattcagt tatttactaa
     9961 attgtctatt gaaaagaata agataagaca aatggggaat aaagcagtta atcaggcaca
    10021 aaagttttca ataaaccaac atacaagaga gattataaat gtatatcaag aaatgagaaa
    10081 taaacagtga aaaatatgga acaaattgat tttgtggtga catgggttaa taataaagat
    10141 gtagattggt gtaaaagaaa gtctgaattt gagaaagaat ataatatatt tcaagattta
    10201 aatagtgaag aacgatatcg tgaatggggc tttatgaaat attggttcag agctgtggaa
    10261 aaatatgccc cttgggtaaa taaaatttat tttataactg aagggcatgt accaaattgg
    10321 ttagatgtaa atcatcctaa attggttcat gttaaacatg aggattatat tgaaaaacag
    10381 tttttgccaa cttttaattc aaacgttata gagatgaatt tgattcattt gaaagattta
    10441 tcagagaaat ttgttctttt taatgatgat actttcataa atgattttgt aaaacaaagt
    10501 gatttttttg aaaataattt acccaaagat acgggtattt ttagtccttt aatacctaga
    10561 gaaaattctt taactcctat tgtattaaac aatatggaga ttattaacaa atatttttca
    10621 aagaaaaaaa ttcttgagca gaatttttct aagtttttta acatcaaata tggaaaacat
    10681 ctattgaaga atatttgttt actgccatgg tcagatttgt taggctttta taatagtcat
    10741 attccagtaa gttattgtaa aagtaatttc ttggaagtct atgagaaaga atatgacatt
    10801 tttaatttga cgtttaaaaa taaatttagg aataaaaatg agattaatca ttggttaatt
    10861 agatattggc aattgtctag cggtaatttc atacctagaa acattaattt tgggaaaaat
    10921 tatgccattt caaatgatcc tacggatatt attaatgaat taaaattttc taaatataag
    10981 attatatgta ttaatgatgg tgaaagtata gatagttttg atgaagtgaa agatctaatg
    11041 attgatgctt ttgaaaaaaa gtttcctgag aaatcgagtt ttgagaaaaa gtgaggcaga
    11101 taagaatgaa tttggaagat ttagtattaa taattttaaa ttataatagt gctaaagata
    11161 cactacgttg tttagaaatt ctacgttctt ttaatatgaa ttttaaaatc attgtagtgg
    11221 ataataattc tacggacaat tcaatagaac tactcaagaa tatagaggat cctcaaacta
    11281 cttttttaat ttctgatgag aatagaggat atggagcagg taataatatt gggattcact
    11341 ttgcagaaaa taatttttct tcaaatatca taggtattat taatccagat atagtcattc
    11401 ccaatcagga agtgataatt tcaatgtata atgttttgaa aaatagtgac tttgctatgg
    11461 ttggtgggtc agtaatcgat aatgagggaa attatagact attaaattca tcatggaatt
    11521 taccttcttt taagagtgtt gtacttgaaa gatttttaat atataatcga cataaagttc
    11581 catattgttt aaatatgtat aatgatgaaa cagcgattgt agattgtgta gcaggttgct
    11641 tttttatgat aaaagctgat gtaatgaagg aaatcggtta ttttgatgaa aatgtttttt
    11701 tatataatga agagaacatt cttggaatga aactgagaga aaagggcttc caatcaatta
    11761 tattaaccaa acagttttac tatcatttgc atgattttga aaaggataag gtagaattat
    11821 ccttgagtaa aaaatgtaaa cgagattggg tgaaatttca gtcacgtaag tattttaccg
    11881 aaaaatatta ttcaaaattt ttaggttttc ttcttttttt gttgaaatat ttaatttgtt
    11941 tcaaattata ataggacact taaaaaataa tattataaag aagaatctga aaggaaactc
    12001 tagtgaaaaa aagtagtacg ttacatatag ggcttattct ttttttgatt gtactgagta
    12061 aaaacttctt taatttagta ccaaatatag cactgttttc tgattttaat cttatgatta
    12121 ttataatcat catgacagtt gttaatatta aatactataa tcgctcaacc aaatatcagt
    12181 atcgttggta tattattttc acattgatat ttgtgttgta tagtgcaatt aatgagaaac
    12241 tattatatgg ccaaccattt ctattaggtt tacttcctca aagacaattt tttttatgtt
    12301 taatgactta tttcccttta agaaagtatt tccaagaaca aaatattagt ttaaaaaaac
    12361 tttatgttgg tattatgaat ttgggatcta tttcatcgtt aatttacatt ttacaaaaga
    12421 tagtaatatt atatggggga acacaatttg ttaacgtaat gtatagtttt gccggatatt
    12481 ttagcgggta tagattgtat gtaggtagtt ctttaattat tttagcaaca ttaatttcta
    12541 ccgcttattt tttagaaaca ttaaaactca agtatctgtg tcaccttata ttaggttggt
    12601 ttactcaaat ttggataacg caaggtcgaa tagagatgat tgttttgcta atttcaacga
    12661 tagtttgcat aatagttcaa ggaagattaa ctagaaagaa aataatttat tggttgctga
    12721 caattttggg actgtggatg attactctaa cacctatttt tgaaaatatt gttggagcta
    12781 ttttaaaagt agatggagca ggtagaggaa gtgattcatt gactattcga gcaattggac
    12841 gacagttata ttgggatcaa ttgaatgaga caacttcaaa acttcttttt ggaacaggat
    12901 atcctaatta taattatgct ttagcctttc aacgtacagg tttttcaagc aatatttttt
    12961 taacagacaa tggttttatg acacatatat atatatatgg tattgtgggt tcctcaatta
    13021 tgggattatt atttttaaaa tatcttaaaa attcaataaa gtatgctaga caatctgcag
    13081 atatgattcc gttgatgtat attatttctt tactaattgt agcctataat attattcttt
    13141 ggtattggaa tgcggacggt acttttatat tagtaatcat gatttgcgca ttggagcatg
    13201 gagaacaatt attacatcag aggaatggag tgtgattaga tgaatttaaa taaagaagtt
    13261 agatggaagg ataagcaata tattgctttt gatttttttg atacaactat ccatagaaat
    13321 tgtcatcctg aagtgatttt atttgaatgg tctaaaaaaa tttctattta tttctctttc
    13381 aaaatatctg ctacagaaat ttattcaatt aggaaaaaat ctgaaataca tgagaagcaa
    13441 gaaaaacaat tggaagaaat taaatatgaa agattacttc aacttgtttt ttatactatt
    13501 ttaagtcgtt tgaagtcaga tgttaccgac tataatcttg aagatttttt aatttatgca
    13561 agaacgtgtg aagaggaaat agaattaaga catattagta ttgatacaga tacaattaat
    13621 tttattgaat ttttaaaaca aaatgggaaa aaaataattt taatttcaga tttttattct
    13681 gataaaaagc taattgaaaa attaatggtt tcattaggga ttagagatta tttctctaaa
    13741 atatttattt caagtgaaat tggcttacgt aagtcatcag gaaatttata tgaatatgtg
    13801 atcaatgaat tgagctgtaa gcctataaat ttacttatga ttggtgataa tatttattct
    13861 gatgtaaaag ttccaaaaaa actaggaata gattcttatc ataaatctta ttcagattca
    13921 catgtgactg tgagtcctaa cgatattgta aaagcgatga ataatgttat ttctcaagct
    13981 tgtactgaat ctttatttaa tctctatata cctgaaatac tttattttat ttcaaagtta
    14041 tacaaagaat tatctgttaa caaagctagt gatatattat tttgtgcaag agaaggtttt
    14101 tttataaaaa aattatttga tctttatcaa aaaaaaatga acttaaagct tattaattca
    14161 cattattttt atgtttctag aaaatcaacg ctatatccat catttaaaaa tattgaggat
    14221 gaagattttg aagttatttt tagacaattt cctgaaatta ctttagaaaa ttttttgatt
    14281 aatttaaatt tttccaataa tgatattaac aatatttcta agcaaacaga aattaaacaa
    14341 acagacaaag tatcagataa atctattatt aacaaattaa aacaaaataa attatttaaa
    14401 gatgtttatg atttgaactg taaagaagaa aaatattctt ttagagaata tttaaagtct
    14461 gtaggagttg agaatgacaa ttctacaata aatatggtag atattggttg gaaaggcacg
    14521 atacaagaca atattcaaaa agcttttcca tctttaaata taaaagggta ttatatgggg
    14581 ttgaattttc aacggtattc tactaggaat agtatgaata agacgggaat actgtttact
    14641 gacgatcctc aaaaaacaaa gttttttaac ttatttaatt ataaatattt attctatgaa
    14701 agaatttttg ttgcagatca tggaccgaca gttagatatg aatttatgaa tggtgttggg
    14761 gtaccaacat tggatacaga tgaaaatcat atagaaattt atagattttc tgaggaattt
    14821 cagattacat ttttcaacac atttgagaaa attttagatt tgttcaatga atcactagta
    14881 acaccagatg aattatttaa cgaaatagct aatttatcgt taaaaaaaca ttgcatctat
    14941 ttacctaggc tttcagtaag tataaaaaaa ttagatagag cagcaaaaga aaattttggt
    15001 attataaaat ctactaacag gaatagtgat aataaggtaa gaaatttttg gaaaaataga
    15061 gattttttat ttttagatta tatatataaa gcgtatggaa agaatagatt gttaaaccct
    15121 atattggata tttacggata ttttgtatat ctgattaaaa cactgcaaat aaaaatagta
    15181 ggggatattt gatgagcatg aaagaaaaat caataaataa aaatgctatt ttgaatatta
    15241 ttttaacact aacaaatatt gtgtttccat taattacttt tccttatatt tctagaattc
    15301 tgaatccgtc aggaataggt gcaatctctt ttttttcatc tattggttct tatggtgttt
    15361 tagttgcctc gcttggaatt tcaacttatg ggattcgggt gattgcaaag gatcgttatc
    15421 ataaagataa gataactaaa atattccaag aattgatagt tattaatagt gtaatgtcta
    15481 ttatagtgac gttcttcctt gttttaatga gtttccgatt agagcagtta agttcagaaa
    15541 aaggtttatt aataatcaca tgtattacta ttttgtcctc tccttttaat ttgaattggt
    15601 tttatagtgg aatagaagag tattcatata taacaaaacg ttcaatattt tttaaattag
    15661 tttcgttgat attaaccttt ttatttgtta aaagtaaaga cgattatatt ctatatgctg
    15721 tgataacatt gttttcaaca ttggcttcca attttataaa tattttggag agtagaaaat
    15781 acatcaattt taatttgaga agggatttag aatttagata tcatctaaaa ccaatgtggt
    15841 atttatttgc ttcgttactt gcagttaata tttatataaa tttggattct gtgatgttag
    15901 gaattattaa tggaaatgat gcggtaggta tttactcaat cgcatcaaaa gtaaaatgga
    15961 ttttattatc agtcgttact tcagtgagtt cagttttatt acccagatta tcattttata
    16021 gcaataaata tgacgaaacg aagtttaata atattttgag aaagtcatct acaataattt
    16081 ttatgatttc aattcctcta acaatttttt ttatgataaa agcgaaagag agtatattat
    16141 tgttaggtgg agagcagtat attcaggcag ttttagcaat gcaaatatta atgccgatct
    16201 tggtaatatc aggtttttct aatattacag gtaatcagat attgatccct actggtaatg
    16261 agaaatattt tatgagagca gtttctatag gagcaatagt aaatttatgt ttaaatttgt
    16321 tgcttatgcc tattttggga attatcggag gtgcgatcgc aactctttgt gcagaatcag
    16381 tccaaatgat tattcaattt tatttttctc gtaataaatt aatgggtaat atttcattaa
    16441 attcaatcaa aaaaatagcc tattcatcaa tttttgcggg tatactgtta atagtaatac
    16501 aaaatattat agagaatttt aatagcttct taaatttagc tgcatctagt tttctatatt
    16561 ttggagtata ttttttctta ttggtattgt ttaaagaaag tacaattaag aaatttctaa
    16621 atcaaatttt ttataaggat atttcatgaa tttattacca attatttatg gagcgattct
    16681 tgatttaata tcagaataat tttttaaagt gaatgaaatc aaagcaataa aagattaaaa
    16741 aataaattgc tatctattat gtttttctca agttaagtaa aacataactc atgaaaacaa
    16801 atttaaaaag gagggactat agtatgaaag gtattattct agcaggtggt tcggggacac
    16861 gtttatatcc tttgactcgc gctgcatcaa aacaacttat gccggtttat gataaaccga
    16921 tgatttacta cccactttca acattgatgc tggctgggat tagggatatt ttgattattt
    16981 ccactccaca ggatttacat cgattccaag agcttcttca agacggatct gagtttgggc
    17041 tcaaactttc ttatgcagag caaccaagtc cagatggttt ggcacaagcc tttatcattg
    17101 gggaagagtt tatttctgat gatagcgttg cgctgatctt aggtgacaat atctatcacg
    17161 gttctgggct ttccaagatg ctacaaaagg cagcgagtaa ggagtcggga gcaactgttt
    17221 ttggctacca tgtcaaggat ccagagcgct ttggtgtggt tgagtttgat caggatatga
    17281 aggctatttc tattgaagaa aagccagagc aacctcgttc aaactatgca gttacaggtc
    17341 tctatttcta tgataatgat gtagtagaga ttgccaagag tattaaacca agtcctcgtg
    17401 gtgaactgga aattacagat gtaaacaagg cttacctaga tcgtggtgat ttgtctgttg
    17461 agcttatggg acgtggcttt gcttggttgg atactggcac tcatgaaagt ttactagagg
    17521 cttcgcagta catcgaaaca gtccaacgga tgcaaaatgt tcaggtagca aacttagaag
    17581 aaattgctta ccgtatgggc tatatcagtc gagaagatgt attggcctta gcccaaccac
    17641 ttaagaaaaa tgaatacgga cagtatctgc tccgtttgat tggagaagca tagatgacag
    17701 ataatttttt cggtaagacg cttgcggcac gcaaggttga agctattcca ggcatgttgg
    17761 agtttgatat ccccgttcat ggagataatc gtggctggtt taaagaaaat ttccaaaagg
    17821 aaaaaatgct tccacttgga tttccagcgt ctttctttgc agaaggaaaa ttgcaaaaca
    17881 atgtatcctt ctcacgtaaa aatgtccttc gaggcctcca cgcagagcct tgggataagt
    17941 acatctctgt agcagatgga gggaaagttc tgggttcttg ggttgatcta cgcgagggtg
    18001 aaacctttgg gaatacctat cagacagtaa ttgatgcaag caagggaatc tttgttcctc
    18061 gaggcgtagc taatggcttc caagttttat cagatacagt gtcatatagc tatctggtca
    18121 atgattactg ggcgcttgaa ctcaaaccca agtatgcctt tgtgaactac gctgatccaa
    18181 gccttggtat tgaatgggaa aatattgcag aagcagaggt ttcagaagca gataaacatc
    18241 atcccctact taaggacgtg aagcctttga aaaaagaaga tttggaataa ggaaaaaata
    18301 tgactgaata caaaaatatt atcgtgacag gtggagctgg ctttatcggt tctaactttg
    18361 tccattatgt ttacgagaac tttccagatg ttcacgtgac agtcctagat aagttgactt
    18421 atgctggaaa tcgcgcgaat attgaggaaa ttttaggtaa tcgtgttgag ttagttgttg
    18481 gtgacattgc tgatgcggag ttggtagaca agttggctgc tcaagcagat gctatcgttc
    18541 attatgcagc ggaaagccac aatgataatt cgctcaatga tccatcgcca tttattcata
    18601 ctaacttcat tggaacctat actcttttag aagctgctcg taagtatgat attcgcttcc
    18661 accatgtatc gacagatgaa gtttatgggg atctcccttt acgcgaagat ttgccaggtc
    18721 atggagaagg gccgggtgag aaatttacgg ctgaaaccaa gtacaatcca agctcgcctt
    18781 actcatcaac caaggcagcc tcagatttga ttgtcaaagc ctgggtgcgt tcttttggag
    18841 tcaaggcaac gatttccaac tgttcaaata actacggtcc ttaccagcat attgagaagt
    18901 ttattccacg acaaatcacc aatatcttga gcggtatcaa gccaaaactt tacggtgaag
    18961 gtaagaacgt tcgtgactgg attcatacca atgaccattc ttcaggagtt tggacaatct
    19021 tgacaaaagg gcaaatcggt gaaacctact tgattggggc tgatggtgag aagaacaata
    19081 aggaagtttt ggaacttatc cttaaggaaa tgggacaagc tgcggatgcc tatgatcatg
    19141 tgactgaccg tgcaggacat gaccttcgct atgcgattga tgctagcaag ctccgtgatg
    19201 agttggggtg gaaacctgaa tttaccaact ttgaagctgg gctcaaggca acaatcaagt
    19261 ggtatacaga taaccaagaa tggtggaaag cagaaaaaga agctgttgaa gccaattatg
    19321 ctaagactca ggagattatt acagtataaa aagcaggaaa tagctgcttt ttattgctat
    19381 attgggaaga gttacatatt agaaaggtct agagatgatt ttaattacag gggcaaatgg
    19441 ccaattagga acggaacttc gctatttatt ggatgaacgt aatgaagaat acgtggcagt
    19501 agatgtggct aagatggaca ttaccaatga agaaatggtt gagaaagttt ttgaagaggt
    19561 gaaaccgact ttagtctacc attgtgcagc ctacaccgct gttgatgcag cagaggatga
    19621 aggaaaagag ttggacttcg ccatcaatgt gacggggaca aaaaatgtcg caaaagcatc
    19681 tgaaaagcat ggtgcaactc tagtttatat ttctacggac tatgtctttg atggtaagaa
    19741 accagttgga caagagtggg aagttgatga ccgaccagat ccacagacag aatatggacg
    19801 cactaagcgt atgggggaag agttagttga gaagcatgtg tctaatttct atattatccg
    19861 tactgcctgg gtatttggaa attatggcaa aaacttcgtt tttaccatgc aaaatcttgc
    19921 gaaaactcat aagactttaa cagttgtaaa tgaccagtac ggtcgtccga cttggactcg
    19981 taccttggct gagttcatga cctacctagc tgaaaatcgt aaggaatttg gttattatca
    20041 tttgtcaaat gatgcgacag aagatacaac atggtatgat tttgcagttg aaattttgaa
    20101 agatacagat gtcgaagtca agccagtaga ttccagtcaa tttccagcca aagctaaacg
    20161 tccgctaaac tcaacgatga gcctggccaa agccaaagct actggatttg ttattccaac
    20221 ttggcaagat gcattgcaag aattttacaa acaagaagtg agataagtag tagaatgatt
    20281 ttctagtcta ataaaagagg cagagaatga actccaaagg agcttaagat gtacgattat
    20341 cttgttgttg gtgcagtctt tgcccatgaa gcagtcttaa aaggaaaaaa agtaaaagtt
    20401 attgaaaaat gaaatcatat cgcgggtaat atctatactc gtgaagagga aggaattcaa
    20461 gttcatcaat atggtgctca tatcttccat acttctgata aggagatctg ggattatgta
    20521 aatcagtttg cagagtttaa ccgttacata aattctcctg ttgcaaacta taagggtgag
    20581 atttataacc ttccttttaa tatgaatact ttcaataaac tctggggagt tgtaacgcca
    20641 gcagaagcac aagctaagat tgatgaacaa cgtgctattt taaatggtaa aactcctgaa
    20701 aatttggaag aacaggcgat ttctcttgta gctacagaca tctacgaaaa attaatcaaa
    20761 gactatacag agaaacagtg gggcaaacca actactgaac ttccatcctt tattattgtt
    20821 tgccagtacg cctgacctat gataacaact attttaacga tacctatcaa gggattccaa
    20881 ttggtggata cactcaaata gttgaaaaat gttggatcat gaaaatattg atgtagaaac
    20941 aaacgttgat ttctttgtga ataaagagca atatctgaaa gattttccta agattgtctt
    21001 tactggtatg attgatgaat tctttgacta taagttgggc gaactagagt accgtagtct
    21061 tcgttttgaa aatgagacct tggatatgga aaattaccaa ggaaatgcag ttgtgaacta
    21121 tacggatgca gaaaccccat atactcgcat tattgaacac aaacattttg agtttgggag
    21181 tcaagcaaag actatcatta ctaaagaaca ttctaaaaca tgggaaaaag gtgatgagcc
    21241 ttattatcca gttaataatg atcgtaataa tcatttgtat aaatcatata aaaaacttgc
    21301 tgatgagcaa gggaatgtta tctttggtgg ccgcttagga cactatcgtt attacgatat
    21361 tcaccaagta attggagcag ctttgcagtg cgtgagaaat gagttaaatt aatactcaat
    21421 gaaaatcaaa gagcaaacta ggaagctagc cacaggttgc tcaaaacact gttttgaggt
    21481 tgcagatgga cgctgacgcg gtttgaagag attttcgaag agtataaaca agtaaaactg
    21541 actaccagtt attatttaga aatagtatta aaaattcctt gactatgtga tatagttgag
    21601 ggatttttaa atgatattca tattttttgc aaagatgttg tttgaaaaat aattttcaaa
    21661 aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga gaaagtttta
    21721 aaggagaaaa tgatgaaaag ttcaagacta tttgcccttg cgggcgtgac attattggcg
    21781 gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga gaagacattc
    21841 tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc taaggctgcg
    21901 acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg ctacgggaac
    21961 tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac ttacacttat
    22021 actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc ggcagtcaaa
    22081 gctcaagac
//
