LOCUS       CR931713               22520 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 6803 (serotype 41a).
ACCESSION   CR931713
VERSION     CR931713.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22520)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22520)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="6803"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC41A_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC41A_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34463.1"
                     /db_xref="GOA:Q4JZD8"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4JZD8"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAP
                     WDAFCVELL"
     gene            322..490
                     /gene="aliB"
                     /locus_tag="SPC41A_0002"
                     /pseudo
     CDS             322..490
                     /gene="aliB"
                     /locus_tag="SPC41A_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(463..1023,1025..1351))
                     /gene="tnp"
                     /locus_tag="SPC41A_0003"
                     /pseudo
     CDS             complement(join(463..1023,1025..1351))
                     /gene="tnp"
                     /locus_tag="SPC41A_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(961..1023,1025..1333))
                     /gene="tnp"
                     /locus_tag="SPC41A_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 7.7e-24"
                     /pseudo
     gene            1584..3029
                     /gene="wzg"
                     /locus_tag="SPC41A_0004"
     CDS             1584..3029
                     /gene="wzg"
                     /locus_tag="SPC41A_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34466.1"
                     /db_xref="GOA:Q4JZ02"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ02"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNVPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1584..1700
                     /gene="wzg"
                     /locus_tag="SPC41A_0004"
                     /note="Signal peptide predicted for SPC1836 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1788..2135
                     /gene="wzg"
                     /locus_tag="SPC41A_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 1.6e-63"
     misc_feature    2313..2756
                     /gene="wzg"
                     /locus_tag="SPC41A_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 5.7e-70"
     gene            3031..3762
                     /gene="wzh"
                     /locus_tag="SPC41A_0005"
     CDS             3031..3762
                     /gene="wzh"
                     /locus_tag="SPC41A_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34467.1"
                     /db_xref="GOA:Q4JZ01"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ01"
                     /translation="MIDVHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMSGITPVIAHIERYDALGNNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    3034..3642
                     /gene="wzh"
                     /locus_tag="SPC41A_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1.5e-36"
     gene            3768..4463
                     /gene="wzd"
                     /locus_tag="SPC41A_0006"
     CDS             3768..4463
                     /gene="wzd"
                     /locus_tag="SPC41A_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34468.1"
                     /db_xref="GOA:Q4JZ00"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ00"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNRNQGDKSGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKL
                     DMPAKTLASKVQVTVPTDTRIVSISVKDKQPEEASRIANSLREVAVEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELFDTRVKRPEDIEDVLQI
                     PLLGLVPDLDKMK"
     misc_feature    3768..3884
                     /gene="wzd"
                     /locus_tag="SPC41A_0006"
                     /note="Signal peptide predicted for SPC1838 by SignalP 2.0
                     HMM (Signal peptide probability 0.721) with cleavage site
                     probability 0.467 between residues 39 and 40"
     misc_feature    3789..4205
                     /gene="wzd"
                     /locus_tag="SPC41A_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1e-55"
     misc_feature    4311..4388
                     /gene="wzd"
                     /locus_tag="SPC41A_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4473..5162
                     /gene="wze"
                     /locus_tag="SPC41A_0007"
     CDS             4473..5162
                     /gene="wze"
                     /locus_tag="SPC41A_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34469.1"
                     /db_xref="GOA:Q4JYZ9"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ9"
                     /translation="MPTLEISQAKLDFVKKAEEYYNSLCTNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITQKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVNKYGSY
                     RNYGDYGKNKK"
     gene            5177..6544
                     /gene="wchA"
                     /locus_tag="SPC41A_0008"
     CDS             5177..6544
                     /gene="wchA"
                     /locus_tag="SPC41A_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34470.1"
                     /db_xref="GOA:Q4JYZ8"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ8"
                     /translation="MNGKVVKPSLAIIHSFLVILLTYLLSAVREAEIASATAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHLIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEIVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     misc_feature    5177..5284
                     /gene="wchA"
                     /locus_tag="SPC41A_0008"
                     /note="Signal peptide predicted for SPC1840 by SignalP 2.0
                     HMM (Signal peptide probability 0.897) with cleavage site
                     probability 0.441 between residues 36 and 37"
     misc_feature    5960..6541
                     /gene="wchA"
                     /locus_tag="SPC41A_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 2.7e-160"
     gene            6531..7337
                     /gene="wciB"
                     /locus_tag="SPC41A_0009"
     CDS             6531..7337
                     /gene="wciB"
                     /locus_tag="SPC41A_0009"
                     /note="member of homology group 16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34471.1"
                     /db_xref="GOA:Q4JYZ7"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ7"
                     /translation="MERSRLIDVKIIVATHKEVKMPQDNSLYLPIHVGRDGKSDIGFI
                     GDNTGDNISSLNPYYCELTGLYWAWKNLDYNYLGLVHYRRYFTKKSQRYSDYISMDEV
                     VLSRGDLDNLLSQNDVLVPKKRRYYIETLYSHYAHTLDGSHLDVARDVIKQLSSEYLT
                     TFDKVMKQRSGYMFNMFIMKKDLANQYFSWLFPILDKMYEQIDVSQLTPFEARLFGRV
                     SELLFNVWLKHKDIKPKELPFMYMEKVDLFEKGKSFLMAKFFGKKYGQSF"
     gene            7321..8418
                     /gene="wcrP"
                     /locus_tag="SPC41A_0010"
     CDS             7321..8418
                     /gene="wcrP"
                     /locus_tag="SPC41A_0010"
                     /note="member of homology group 89"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34472.1"
                     /db_xref="GOA:Q4JYZ6"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ6"
                     /translation="MDRVFEMLEKESPLFSVIVPTYKISESNLRQCIDSLLYDNQDVE
                     IILVDDNANSDICGKVIDEYAEKYNNISVIHQENQGVSVARNAGMSIAVGKYLVFVDP
                     DDWVAENFYSQMAFAVQKNPSSDVIILAAIVDYNGKRFTNYFWHTSRSFCGKDKDDLE
                     LQLIAKGATSYFPTEIGVGVPWAKIYRNEFVRANGLVFNPSLRRMQDNIFNMYAFEFA
                     NEIVYINEPIYYYRKSMDSVTNKKNDKVIYYFDLVNDEVEKFIQKFNKPKIFEDALHI
                     KRLIGINSYYKLYFQFATTSSEKKKMRQEFRELLEREEYANSLKQVNTAYLLPKEKIF
                     ISILKQKHLRIFSFLQKLEKLSARLKSRHFS"
     misc_feature    7366..7905
                     /gene="wcrP"
                     /locus_tag="SPC41A_0010"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 2.9e-31"
     gene            8426..9343
                     /gene="wcrQ"
                     /locus_tag="SPC41A_0011"
     CDS             8426..9343
                     /gene="wcrQ"
                     /locus_tag="SPC41A_0011"
                     /note="member of homology group 106"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34473.1"
                     /db_xref="GOA:Q4JYX5"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4JYX5"
                     /translation="MRQLTLKLVSIIYKVTKRIPISFISNLGERIYSLKDSYVFDVLS
                     KLGVDKESTYDLMPPDLFLNKIWICWFQGEDKAPDLVKKCINSVRKHASGYDVIILTE
                     DNIEEYVTLPNIVLTKYKNGLFSRTHFSDIVRLNLLAQQGGLWIDATIFMTRDLDLSI
                     FFKNDFVSLRTTIKSSPLFITGYWTTYFVYMPSNFKLVQYTALLLNKYIEKYDRFIDY
                     FLQDYIITKAIKDLNYESYMEERPVLGNQRWLLADLANKVVTSELLQQFKQDTVGIYK
                     VTYKSKYIRKKNGRETVYKKIVEDGECLE"
     misc_feature    8477..9316
                     /gene="wcrQ"
                     /locus_tag="SPC41A_0011"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 2.8e-47"
     gene            9324..10214
                     /gene="wcrR"
                     /locus_tag="SPC41A_0012"
     CDS             9324..10214
                     /gene="wcrR"
                     /locus_tag="SPC41A_0012"
                     /note="member of homology group 90"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34474.1"
                     /db_xref="GOA:Q4JYX4"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JYX4"
                     /translation="MENALNNKIGIVILNYLNWEDTLECINSLRSQSDQDFEAVIVEN
                     GSPNESVSRIRDYIKNDKNIHLYVVENNLGYANGNNMGILYLKNRYSINRILLTNNDV
                     IFDDEDYIKKLEDIKYSNTIGAIGTKIIGSDGLNQNPAYFPISFSSSIKSLLINLLAF
                     SKVITFIKKRFLSSWTKRANDFSNPKTDEQKYFLHGSVIFLTENYLDRFMGLYGGTFL
                     YYEEVILGIIFEKAGLDMLYVPDFSIYHKEDQSSLESFANDDLIRRKFLLKSIFSSFK
                     VHFCATNRLSILVKESIKYD"
     misc_feature    9351..9851
                     /gene="wcrR"
                     /locus_tag="SPC41A_0012"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 1.9e-13"
     gene            10207..11466
                     /gene="wzy"
                     /locus_tag="SPC41A_0013"
     CDS             10207..11466
                     /gene="wzy"
                     /locus_tag="SPC41A_0013"
                     /note="member of homology group 121"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34475.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ3"
                     /translation="MIKFNYSKLALIYQFIIIFFLGAWYKNSIQFKIFLISIDTIISL
                     FYLYKNNLSRSDLKKVYILITTVLVSLFLPSFMNRVSFILLILQKLYIFNHIINDIKF
                     EYLLSVFLQFIVLLTFCMGLEFISLGQFNPFKTFYAPRVLLDMSFKVGTPLYFLRSSL
                     EHPLITSIVLVVTGPFLFLLEKKWLRYVCVFLNISLIFFIQKRTAYILVSIGVVCFAL
                     YYLKYINRRFQLNKITSVIFLMTLFIIALSFIRVQGDYVLNIIFSKFSALQDADSFSL
                     NNRVINAKTGLDVIFDQNVINIFIGNGYDFLPNFFEQYNVYVIRNGFYVIDNTYISFL
                     ADYGMIGLFLVLLYIINAIRKSMTNIYKIKSKKEQLFMLYSIIGIINLMVSIAFFDIY
                     AWYTLLTLLIFLISVVTSYCKFHSNKF"
     gene            11508..12752
                     /gene="wcrW"
                     /locus_tag="SPC41A_0014"
     CDS             11508..12752
                     /gene="wcrW"
                     /locus_tag="SPC41A_0014"
                     /note="member of homology group 122"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAI34476.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ2"
                     /translation="MTLKNEVKNIKRTIEKNFFHKDFTSISDIKNYQIEISKNLRPRL
                     NLLITSMNSQDVYAGIKSAVDFFMKFKKFDIDLRIIVMGKKIDEPSLYQVPGFEFIKD
                     YSIENDSESRIICDLSKNRSPLFIRERDYFLSTMWYTAYNANNVLDEQKRIFGKRMPM
                     VYLVQDYEPGFYPWSSEYLLAESTYHLDNQLVVFNSKYLKEFFDANGYRFENSYYFDP
                     VLNEKLGEILNLAELSNIERKNRILFYGRPSKARNAFQLICMALEKWSVLDERSSNWE
                     IFSAGEDLKDIKLNNSIVIKSLGKMSVEEYAKFMLESKIGISLMASPHPSYPPLEMAT
                     FGMKVITNSFVTKDISDFNENIISIEHININKLAEELHFLTTSDIEYKISKNDDYING
                     ISQLDTIVDEIAGHLQFRHSEV"
     gene            12749..14197
                     /gene="wzx"
                     /locus_tag="SPC41A_0015"
     CDS             12749..14197
                     /gene="wzx"
                     /locus_tag="SPC41A_0015"
                     /note="member of homology group 123"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34477.1"
                     /db_xref="GOA:Q4JYZ1"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ1"
                     /translation="MIVKRKSIARNYLLNLIKTTLSILFPLISYPYVSRILSVDGLGA
                     INFSTSFVNYFVLIAIFGINVYAVREGAKYRDDKKLLGKFVTEMLLVSICTAMISFSL
                     LTVSLLLPALSEYRSLILIFSITIIFNVVGMEWFFQLMEDYQYITLRAIIFQILSLIF
                     LFIFVKNRNDIYVYALITVAANAGSQILNLFRLRKEVEIFRYKDYNIRNYFKPMFLIF
                     LTLLSMNMYRYLDVTFLGFFKNDRSVGYYSLATKITSAIISMLSSVTVILTPRLAYHY
                     KKEEFDKFYKIAYSSFDLILLLAIPVVIGVFSFSSILVDFLGGSTFVSSVLTVEILSL
                     TILFSNLNALLITPILTVMNREKAVLKIFIIALIFNVITNMLLIPVMDFNGSALVTVL
                     TEGIICILSLISIKSVFNVRRLFKNLFQYLVASIFIIVIKIVISQYVSSNYIIFISTA
                     LLSAILYFLTLILLRNELVLQLIIEVRKKIYR"
     misc_feature    12770..13576
                     /gene="wzx"
                     /locus_tag="SPC41A_0015"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 1.1e-44"
     gene            14213..14885
                     /gene="wcrX"
                     /locus_tag="SPC41A_0016"
                     /pseudo
     CDS             join(14213..14239,14239..14469,14469..14885)
                     /gene="wcrX"
                     /locus_tag="SPC41A_0016"
                     /note="member of homology group 124"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyl transferase"
     gene            14956..16176
                     /gene="ugd"
                     /locus_tag="SPC41A_0017"
     CDS             14956..16176
                     /gene="ugd"
                     /locus_tag="SPC41A_0017"
                     /note="member of homology group 20"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAI34479.1"
                     /db_xref="GOA:Q4JYZ0"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4JYZ0"
                     /translation="MKIAVAGTGYVGLSIAVLMAQHHEVVAVDIISEKVNLINNGKSP
                     IKDDYIEEYLATKPLNLVATLDTNLAYQNADFVIIAAPTNYDSEKNFFDTSAVESVIE
                     TVLETNPNAVMVIKSTVPVGYTQSIRNKYKTSNILFSPEFLRESKALYDNLYPSRIIV
                     GLDMDDAYLKERAETFAELLQEGAVKEAIEILYMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDTKAIIEGIGLDPRIGSQYNNPSFGYGGYCLPKDSKQLLANYKDVPQ
                     NMITAIVESNRTRKDFIAEQILKLAGVSNNGEIYPKDVIIGLYRLTMKSNSDNFRQSS
                     IQGVMKRLKAEGANVIIYEPTLSDDETFFGSKIVNDLEHFKSISNVIVANRYDDLLKD
                     VSDKVYSRDIFKRD"
     misc_feature    14956..15513
                     /gene="ugd"
                     /locus_tag="SPC41A_0017"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.1e-50"
     misc_feature    15541..15822
                     /gene="ugd"
                     /locus_tag="SPC41A_0017"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.8e-36"
     misc_feature    15904..16155
                     /gene="ugd"
                     /locus_tag="SPC41A_0017"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 9e-07"
     gene            16189..17289
                     /gene="glf"
                     /locus_tag="SPC41A_0018"
     CDS             16189..17289
                     /gene="glf"
                     /locus_tag="SPC41A_0018"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34480.1"
                     /db_xref="GOA:Q4JYY9"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYY9"
                     /translation="MYDYLIIGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYINQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTADMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGIDFFAHRE
                     ELEASAEKVVFTGMIDRYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     misc_feature    16624..17226
                     /gene="glf"
                     /locus_tag="SPC41A_0018"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 5e-138"
     gene            17317..18186
                     /gene="rmlA"
                     /locus_tag="SPC41A_0019"
     CDS             17317..18186
                     /gene="rmlA"
                     /locus_tag="SPC41A_0019"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI34481.1"
                     /db_xref="GOA:Q4JYY8"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4JYY8"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLT
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEHPRSNYAVTGIYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLGRGDLSVEVMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    17320..18036
                     /gene="rmlA"
                     /locus_tag="SPC41A_0019"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 6.4e-118"
     gene            18187..18780
                     /gene="rmlC"
                     /locus_tag="SPC41A_0020"
     CDS             18187..18780
                     /gene="rmlC"
                     /locus_tag="SPC41A_0020"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI34482.1"
                     /db_xref="GOA:Q7BTQ6"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q7BTQ6"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     misc_feature    18223..18753
                     /gene="rmlC"
                     /locus_tag="SPC41A_0020"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 8.8e-16"
     gene            18793..19842
                     /gene="rmlB"
                     /locus_tag="SPC41A_0021"
     CDS             18793..19842
                     /gene="rmlB"
                     /locus_tag="SPC41A_0021"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI34483.1"
                     /db_xref="GOA:Q4JYY6"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYY6"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGERPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLREELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    18808..19764
                     /gene="rmlB"
                     /locus_tag="SPC41A_0021"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 7.3e-05"
     misc_feature    18811..19551
                     /gene="rmlB"
                     /locus_tag="SPC41A_0021"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 3.3e-76"
     misc_feature    18811..19755
                     /gene="rmlB"
                     /locus_tag="SPC41A_0021"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0047"
     misc_feature    18814..19626
                     /gene="rmlB"
                     /locus_tag="SPC41A_0021"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.7e-05"
     gene            19908..20759
                     /gene="rmlD"
                     /locus_tag="SPC41A_0022"
     CDS             19908..20759
                     /gene="rmlD"
                     /locus_tag="SPC41A_0022"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI34484.1"
                     /db_xref="GOA:O54665"
                     /db_xref="HSSP:1N2S"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:O54665"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    19908..20756
                     /gene="rmlD"
                     /locus_tag="SPC41A_0022"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 3.4e-148"
     misc_feature    19911..20540
                     /gene="rmlD"
                     /locus_tag="SPC41A_0022"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 5.6e-19"
     misc_feature    19911..20552
                     /gene="rmlD"
                     /locus_tag="SPC41A_0022"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0001"
     misc_feature    19914..20642
                     /gene="rmlD"
                     /locus_tag="SPC41A_0022"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.8e-08"
     gene            order(20835..21730,21753..21962)
                     /gene="tnp"
                     /locus_tag="SPC41A_0023"
                     /pseudo
     CDS             join(20835..21245,21245..21730,21753..21962)
                     /gene="tnp"
                     /locus_tag="SPC41A_0023"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
                     /db_xref="PSEUDO:CAI34485.1"
     misc_feature    join(20841..21245,21245..21280)
                     /gene="tnp"
                     /locus_tag="SPC41A_0023"
                     /note="HMMPfam hit to PF03050, Transposase IS66 family,
                     score 0.00045"
                     /pseudo
     gene            22161..>22520
                     /gene="aliA"
                     /locus_tag="SPC41A_0024"
     CDS             22161..>22520
                     /gene="aliA"
                     /locus_tag="SPC41A_0024"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34486.1"
                     /db_xref="GOA:Q4JYY4"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4JYY4"
                     /translation="MMKSSKLLALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    22161..22253
                     /gene="aliA"
                     /locus_tag="SPC41A_0024"
                     /note="Signal peptide predicted for SPC1856 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.804 between residues 31 and 32"
     misc_feature    22407..22475
                     /gene="aliA"
                     /locus_tag="SPC41A_0024"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     7298 a   3427 c   4535 g   7260 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa cactgcggct aaagaagtac ttgaaaaaca
      121 ggtcttggct ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcgtat aaaaacaagg gaggactgta taaaagacag aaatcctttg
      241 ttttttataa ccaaagttta taaactttca ttcttgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gatgaacata aagaagcgtg tccttagtgc aggcctgact
      361 tttgcatctg ctttgctttt agctgcttgc ggccaatcag gttcagatac aaaaacttac
      421 tcatcaacct ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat
      481 aatatagtca attgaaacaa gaacaagaca aaagagcctc ataaaaggta ttgcaacttg
      541 gtaatacctt tttgaggtgc tttttgatat gagcccatgt tttctcaata ggattgtact
      601 caggtgagta gggaagaaga ggtaaaagtt tatgccaaac ttttcgcata aaagttctag
      661 cttccccatt ctatggaatc ttgcattatc cataataata accgatggtg tggttaatgt
      721 tggtaagaga aacttctgaa accatacttc aaaaaagtcg ctcgtcatcg tctcttcgta
      781 agtcattgga acgattaatt caccatttat tagacctgca accaaagaaa tcctctgata
      841 tcttcttcca gatactttgc ctcttcttaa ctgacctttt aatgagcgac catattctcg
      901 ataaaaataa gtatcgaatc ctgtttcgtc aatctaaaca ggtgctaggt gctttaaact
      961 attaaaattc ttaagaaata aggctacttt ttctgggtct tgttcatagt aggtgtggtt
     1021 ctttttttcg agtgtagccc atagctttga gcgcatagtg gatggtagtt ggatgacagc
     1081 caaattcaga agctatttca gtcaaataag cgtctggatt attagtaaga tagtttttaa
     1141 gtctatctct atcaactttt cttggttttg ttccttttac ttggtggttt agctctcctg
     1201 ttttctcttt tagctttaac cagccataaa tggtattacg tgagatttgg aaaacgtgtg
     1261 atgcttctgt tatactacct gttcgctcac aataagagag aactttttta cgaaaatcta
     1321 ttgaatatgc cataaaaaga ttataccaca ttgtgtacta tattatattg aaactagaat
     1381 agtacacatc tgcttctaaa atattgttag aaaacgattt gactgtcctg atcaatttgt
     1441 catgttctta tttcatttta ctatattttt ggttcgcggg aagtctacta agatacttaa
     1501 agatgcagat agtgaaaaaa ggtgtagaca ttaccgtaaa aaagtgatat aatcgtaaga
     1561 tgttcaatgt ataggtgtta atcatgagta gacgttttaa aaaatcacgt tcacagaaag
     1621 tgaagcgaag tgttaatata gttttgttga ctatttattt attgttagtt tgttttttat
     1681 tgttcttaat ctttaagtac aatatccttg cttttagata tcttaatcta gtggtaactg
     1741 cgttagtcct actagttgcc ttggtagggc tactcttgat tatctataaa aaagctgaaa
     1801 aatttactat ttttctgttg gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag
     1861 tccagcagtt tgttggactg accaatcgtt taaatgcgac ttctaattac tcagaatatt
     1921 cgctcagtgt cgctgtttta gcagatagtg agatcgaaaa tgttacgcaa ctgacgagtg
     1981 tgacagcacc gactgggact gataatgaaa atattcaaaa actactagct gatatcaagt
     2041 caagtcagaa taccgatttg acggttaacc agagttcgtc ttacttggca gcttacaaga
     2101 gtttgattgc aggggagact aaggccattg tcctaaatag tgtctttgaa aatatcatcg
     2161 agttagagta tccagactac gcatcgaaga taaagaagat ttataccaag ggattcacta
     2221 aaaaagtaga agctcctaag acgtctaaga atcagtcttt caatatctat gttagtggaa
     2281 ttgacaccta tggtcctatt agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg
     2341 tcaatcgtga taccaagaaa atcctcttga ccacaacgcc acgtgatgcc tatgtaccaa
     2401 tcgcagatgg tggaaataat caaaaagata aattaaccca tgcgggcatt tatggagttg
     2461 attcgtccat tcacacctta gaaaacctct atggagtgga tatcaattac tatgtgcgat
     2521 tgaacttcac ttctttcttg aaaatgattg acttattggg aggggtagat gttcataatg
     2581 atcaagagtt ttcagctcta catgggaagt tccatttccc agtagggaat gtccatctag
     2641 actctgagca agctctaggt tttgtacgtg aacgctactc actagccgat ggagaccgtg
     2701 accgcgggcg caatcaacaa aaggtgattg tggctatcct tcaaaaatta acgtcaaccg
     2761 aagcactgaa aaattatagt acgatcatta atagcttgca agattctatc caaacaaatg
     2821 tgccacttga gactatgata aatttggtca atgctcagtt agaaagtgga ggaaattata
     2881 aagtaaattc tcaagattta aaagggacag gtcggatgga tcttccttct tatgcaatgc
     2941 cagacagtaa cctctatgtg atggaaatag atgatagtag tttagctgta gttaaagcag
     3001 ctatacagga tgtgatggag ggtagatgaa atgatagacg tccattcgca tatcgttttt
     3061 gatgtagatg acggtcccaa gtcaagagag gaaagcaagg ctctcttggc agaatcctac
     3121 aggcaggggg tgcgaaccat tgtctctacc tctcaccgtc gcaagggtat gtttgaaact
     3181 ccggaagaga agatagcaga aaactttctt caggttcggg aaattgcaaa agaagtagca
     3241 gatgatttag tcattgctta cggggctgaa atttactaca caccagatgt tctggataag
     3301 ctgggaaaaa agcggattcc gaccctcaat gatagtcgtt atgccttgat agaatttagt
     3361 atgaacactc cttatcgcga tattcatagc gccttgagca agatcttgat gtcgggaatt
     3421 actccagtca ttgcccacat tgagcgctat gatgctcttg gaaataatga aaaacgcgtt
     3481 cgagaactga ttgatatggg ctgttacacg caagtaaata gttcacatgt cctcaaacca
     3541 aaactttttg gagaacgtta taaattcatg aaaaaaagag ctcagtattt tttagagcag
     3601 gatttggttc atgtcattgc aagtgatatg cacaatctag acggtagacc tcctcatatg
     3661 gcagaagcat atgaccttgt tacccaaaaa tacggagaag cgaaggctca ggaacttttt
     3721 atagacaatc ctcgaaaaat tgtaatggat caactaattt aggagaaatg atgaaagaac
     3781 aaaacacgat agaaatcgat gtatttcaat tatttaaaac cttgtggaaa cgcaagctaa
     3841 tgattttatt agtggcactt gtgacaggtg cgggggcttt tgcatatagc acttttattg
     3901 ttaagccaga atatacgagt accacgcgaa tttacgtagt gaatcgcaat caaggagaca
     3961 agtcggggct gacaaatcag gatttgcagg caggatctta tctggtaaaa gactaccgtg
     4021 agattatcct ttcgcaggat gcattggaaa aagtagcgac aaatttgaag ttggacatgc
     4081 cagcaaaaac gttagctagc aaagttcaag tgactgtacc aactgacact cgtatcgtct
     4141 caatctctgt caaggataaa cagccagagg aagccagtcg tatcgccaat tctctacgag
     4201 aagttgctgt agaaaagatc gtcgctgtaa cgcgagtatc tgatgtaacg acgcttgaag
     4261 aagcgcgacc agctacgact ccttcttctc caaatgttcg acgcaattcc ttgtttggtt
     4321 ttcttggagg agcagtcgta acagtaattg ctgttctttt gattgagttg ttcgacaccc
     4381 gtgtgaaacg tcctgaagat attgaagatg tactgcaaat tccactttta gggctcgttc
     4441 cagatttgga caaaatgaaa taggaggaag ttatgccaac gttagaaatc tcacaggcaa
     4501 aattggattt tgtaaaaaag gcagaggaat attataactc tttgtgcacg aacctacagt
     4561 taagtggaga tggtttgaaa gtattttcta tcacttctgt gaaactagga gaaggaaaat
     4621 caacgacttc caccaatatc gcttgggctt ttgcgcgtgc aggttacaaa acgctgctga
     4681 ttgatggaga tattcgcaat tctgttatgt taggtgtctt taaagcaagg gataagatta
     4741 caggcctgac agaattttta tcaggaacta cagacctatc acaagggctt tgtgatacca
     4801 atatcgaaaa tctctttgta attcaggctg gctctgtgtc accgaatccg acagctcttc
     4861 ttcaaagtaa gaatttcagt acaatgcttg aaaccttgcg taaatatttt gactacatca
     4921 ttgtagatac tgctcctgtc ggtgtcgtga ttgatgcggc tattattacg caaaaatgcg
     4981 atgcttctat tttagtgacg gaggcaggtg aaataaatcg acgggatatt caaaaagcaa
     5041 aagaacagtt ggaacacaca gggaagccgt ttttgggagt tgtgttgaat aaattcgata
     5101 cttcagtaaa caaatacggt tcttatagaa attatggaga ttacgggaaa aataaaaaat
     5161 agattgaggg atagagatga atggaaaagt agtaaagcct tcattggcca taatccatag
     5221 ttttcttgtt attttattga cttatctact tagtgctgtg agagaagcgg agattgcttc
     5281 agcaacagct attgcacttt atatcctcca ttattttgtc ttttatatca gtgattatgg
     5341 acaggatttc tttaaaaggg gatatttgat tgaacttgtc cagacattga aatatatcct
     5401 attctttgca ctagcgatta gtatttctaa ttttttctta gaggatcgat ttagtatttc
     5461 cagacgaggc atgatttact tcctcacatt acatgctctc ttagtctatg tgctaaacct
     5521 atttatcaag tggtattgga agcgggctta tcccaacttt aaaggaagta agaagattct
     5581 cctgcttaca gcaacttctc gtgtcgaaaa ggtactggat agattaatag aatcaaatga
     5641 ggttgttggg gagttggtag ccgtcagtgt cttagataaa ccagattttc agcatgattg
     5701 tttaaaggta gtagcagagg gggagatagt aaactttgcg actcatgagg tggtcgatga
     5761 agtctttatc aatcttccaa gtgaaaaata caatattgga gagcttgtct ctcagtttga
     5821 aacgatggga attgatgtaa cagtcaatct aaatgctttt gatcgtagtt tggcacgtaa
     5881 caagcaaatt cgtgagatgg cagggttaaa cgttgtgact ttttctacaa cattttataa
     5941 gactagtcat ctaattgcta agcggattat tgatatcgtg ggtgcattgg tagggctgat
     6001 attatgtggt ttagtcagta ttgtactggt tcctttgatt cgaaaggatg ggggctctgc
     6061 tatttttgct cagacgcgta taggaaaaaa tggtcgtcag ttcacttttt ataagtttcg
     6121 ctctatgtgt gtagatgccg aggcgaaaaa aagagaactc atggaacaaa ataccatgca
     6181 gggtggaatg tttaaggtgg acgatgatcc tcgtatcacg aaaattggtt gttttatacg
     6241 gaagactagc ttggacgagc taccacagtt ttacaatgtt ctaaagggag atatgagttt
     6301 ggtaggtaca cgaccaccaa cagtggacga gtatgagcac tataccccag aacaaaaacg
     6361 ccgactaagt tttaaacctg gcataacagg tttatggcag gtcagcggac gaagtgagat
     6421 caagaatttc gatgaaattg tcaaattaga tgtagcctat atagacgatt ggacaatttg
     6481 gaaagatatt gagattttat tgaagacagt taaagttgta ttgatgaagg atggagcgaa
     6541 gtagattgat agatgtaaaa atcattgtgg caacacataa agaagttaaa atgcctcaag
     6601 acaatagtct ttaccttcca atacatgttg ggagagacgg taaatcagat attggtttta
     6661 tcggtgataa tactggcgat aatatatcct ctctaaatcc atattattgt gaattgacgg
     6721 gactttattg ggcatggaag aatcttgatt ataattactt aggtttagtt cattaccgtc
     6781 gttattttac aaaaaaatca caaagatatt cagattatat cagtatggat gaagttgttt
     6841 tatctcgagg tgatttagat aatcttcttt cccaaaatga cgttttagtt cctaagaaga
     6901 ggcgatacta tattgaaacg ctctattcac actacgctca tactttggat ggaagtcatc
     6961 ttgatgttgc tcgtgatgta attaaacagt taagttcaga atatttaacg accttcgata
     7021 aggtcatgaa gcaacgtagt ggttacatgt tcaatatgtt tattatgaaa aaagatttgg
     7081 caaatcagta tttttcttgg ttatttccta ttttagacaa gatgtatgag caaatagatg
     7141 tatcccagtt aacacccttt gaagctagac tattcggtcg tgttagtgaa ttattattta
     7201 atgtgtggtt aaaacataag gacattaaac caaaagagct accatttatg tatatggaaa
     7261 aagtagattt gtttgaaaaa gggaaatcct tcttaatggc caaattcttc gggaaaaaat
     7321 atggacagag tttttgaaat gttagaaaaa gaatctccac tttttagtgt tattgttcca
     7381 acctataaga tatcagaatc taatctacgc caatgcatag actctctgtt atatgataat
     7441 caagatgttg aaattatttt ggtggatgat aacgcgaact cagatatatg tggtaaagta
     7501 atagacgaat atgctgaaaa atataataat atttcagtta ttcatcagga aaaccaaggt
     7561 gtgtcagtcg caagaaatgc tggtatgtct attgctgtag gaaagtatct tgtttttgta
     7621 gaccctgatg attgggttgc tgaaaatttt tatagccaaa tggcttttgc ggttcaaaaa
     7681 aatccttcaa gcgatgtgat tatattagct gctattgtag actacaatgg taaacgattt
     7741 acgaattatt tttggcacac ttctcgttct ttttgtggaa aagacaaaga tgatttggaa
     7801 cttcaattga ttgccaaagg agcaacgagt tattttccaa ctgagatagg ggttggtgtt
     7861 ccttgggcaa aaatttatcg taatgagttt gtgcgagcaa atggcttggt ttttaatcct
     7921 tctcttcgtc gaatgcaaga taatattttc aatatgtatg cattcgaatt tgcgaatgaa
     7981 atcgtctaca ttaatgagcc gatttactat tatagaaaga gtatggatag tgtaactaat
     8041 aagaaaaatg ataaagtaat ttattatttc gacttagtta atgatgaggt tgaaaaattt
     8101 attcaaaaat ttaataaacc taaaatattt gaagatgctc tgcatataaa aagacttata
     8161 ggaatcaatt cgtattataa gttgtatttt cagtttgcga ctacttcaag cgagaaaaag
     8221 aaaatgcgac aagaatttcg tgaactttta gaaagggaag aatatgcaaa ttcgttaaaa
     8281 caagtgaata cagcctatct tctcccaaaa gaaaaaattt ttataagtat tttaaagcag
     8341 aaacacttgc gaatattttc ctttttacaa aaacttgaaa aattatctgc gagattaaag
     8401 agccgtcatt ttagttagag ggaatatgag acagttaaca ttaaaattag ttagtatcat
     8461 ttataaagta acaaaacgaa tacctatatc ttttatttct aatttaggcg agaggattta
     8521 ttcactaaag gattcctatg tttttgacgt attaagtaaa ttgggagtcg ataaagagag
     8581 cacctatgat ttgatgccac cagatttatt tttgaataaa atttggattt gctggtttca
     8641 gggtgaggat aaagcaccag atttagtaaa aaagtgcatc aatagtgtta gaaaacatgc
     8701 ctcaggctac gatgtcatta ttttaacgga agataatata gaagaatatg ttacacttcc
     8761 aaatattgtt ttaacaaaat ataaaaatgg attatttagc cggactcatt tttcggatat
     8821 agttcgattg aatcttcttg cacaacaggg aggactttgg attgatgcaa cgatttttat
     8881 gactagggat ttagatttgt ctatattttt caaaaatgat tttgtaagct tgagaactac
     8941 aataaaatct agtcctcttt ttattacggg gtactggacg acatattttg tatatatgcc
     9001 ctctaatttt aaattggttc aatatactgc tttattatta aataaataca ttgagaaata
     9061 tgatcgcttt atagattatt tcttacaaga ttatataatt actaaggcaa ttaaagattt
     9121 gaattatgaa tcatacatgg aagaacggcc tgtattggga aatcaacgtt ggcttttagc
     9181 agatttagct aataaagttg tgacctcaga acttcttcaa caatttaagc aagatacggt
     9241 aggaatttat aaagtgacat ataaatccaa gtatattaga aaaaaaaatg gtagggaaac
     9301 ggtttataaa aaaattgtag aggatggaga atgccttgaa taataaaata ggaattgtta
     9361 ttttaaatta tcttaattgg gaggatactt tagaatgcat aaatagtttg cgctcacaaa
     9421 gtgatcaaga ttttgaagct gtcatagtag aaaatggttc tccaaatgaa tctgtttcta
     9481 ggattagaga ttatataaaa aatgacaaga atattcatct ttatgtagta gagaataact
     9541 taggttatgc aaatggaaat aatatgggca tcctctactt aaaaaataga tactctataa
     9601 atagaattct attaactaat aatgatgtta tttttgatga tgaagactac ataaaaaaat
     9661 tagaagatat taagtatagt aacacaattg gagctattgg aacaaaaatt attggttctg
     9721 atggtttaaa ccaaaatcca gcttattttc caatttcttt tagttctagt ataaaatcac
     9781 ttcttattaa cttattggca ttttctaaag ttatcacttt tatcaaaaag cgttttctat
     9841 cttcatggac gaaaagagct aatgactttt caaatccaaa aaccgatgaa caaaaatact
     9901 tcctacatgg atcagtcatt tttcttacgg aaaattattt agataggttt atgggattgt
     9961 atggagggac ttttctttac tatgaagaag taatcctagg tattatattt gaaaaagcag
    10021 gtcttgatat gttgtatgta cctgactttt caatttacca taaagaagat caatcatctt
    10081 tggaaagttt tgcaaatgat gatttgatta ggcgtaaatt tttattgaaa agcatattct
    10141 ctagctttaa ggtacatttt tgtgcaacga atagactctc tatactggtg aaggagtcaa
    10201 taaagtatga ttaaatttaa ttattctaaa ttagcattaa tttaccagtt tataataatt
    10261 ttttttctgg gtgcttggta taagaatagc attcagttta aaattttttt gatatctatt
    10321 gatactatca tttctttatt ttatttatat aaaaataatt tatctagaag tgacttaaaa
    10381 aaagtttata tcttgataac tacagtgtta gtaagcttat ttttaccatc gtttatgaat
    10441 agagtatctt ttatacttct catattgcaa aaattatata tatttaacca tattattaat
    10501 gatataaagt ttgaatattt gctctcagtc tttctacaat ttattgtact actaaccttt
    10561 tgtatgggat tagaattcat ttcattagga caatttaatc cgtttaaaac attttatgca
    10621 ccaagagttc ttcttgatat gagttttaaa gtcggaacac ctttatattt tttgagatca
    10681 agtttagagc atcctctaat aacttcgatt gtattagtag ttactggccc tttcttattc
    10741 cttttagaaa agaaatggtt gagatatgta tgtgtgtttc taaatattag tttaatcttt
    10801 tttattcaga agagaactgc gtatatattg gtatcgattg gagttgtatg ttttgctttg
    10861 tattatctaa aatatattaa tcgtagattt caattgaata aaataacttc agtgatattt
    10921 ttaatgacac tatttataat tgctttatcc tttataaggg tgcaaggtga ttatgtatta
    10981 aatattattt ttagtaaatt ttctgcttta caagatgcag atagtttctc gctaaataat
    11041 cgtgtaatta atgctaaaac tggattagat gtaattttcg atcaaaatgt tataaatata
    11101 ttcattggga atggatatga ctttttacct aatttttttg aacaatacaa tgtgtatgta
    11161 attcggaatg gtttttatgt gattgacaat acatatattt catttcttgc cgactatgga
    11221 atgattggtc tgttcttagt attgttatat attataaatg cgatccgaaa aagtatgact
    11281 aatatttaca aaataaagag taaaaaagaa caattattta tgttgtatag tattataggt
    11341 attatcaatt taatggtatc aatagctttt tttgatatat atgcttggta cacgctatta
    11401 acgttattga tttttttaat atcagtagtg acttcttatt gtaaatttca ttccaataag
    11461 ttttagtgtg tacaatcatt ataattagca aaaagaagga aatctgaatg actctcaaaa
    11521 acgaagttaa aaacataaaa cgaacaatag aaaaaaattt ttttcataag gattttacat
    11581 ctatatctga tattaagaat tatcagattg aaatttctaa gaatctaagg ccacgtctta
    11641 atttattaat tacttcaatg aactctcagg atgtatatgc tggcatcaaa tcagcagtgg
    11701 atttttttat gaagttcaaa aaatttgata tagatttaag aatcattgta atgggaaaaa
    11761 aaatcgatga accgtctctt tatcaagttc ctggttttga atttattaaa gactattcaa
    11821 ttgagaatga tagtgagtct aggattattt gcgatttatc taagaatcgt tctccattgt
    11881 ttattaggga gcgtgattat tttctatcaa caatgtggta cactgcttat aatgctaaca
    11941 atgtgctgga tgagcaaaaa agaatttttg ggaaacggat gcccatggtt tatctagttc
    12001 aagactatga accaggtttc tatccatggt cctcagagta tcttttggct gagagcacat
    12061 atcatctaga taaccagctt gttgtcttta attctaagta tttaaaagaa ttttttgatg
    12121 caaatggtta tagatttgaa aatagttatt attttgatcc agttttaaat gaaaaattgg
    12181 gggagattct taatttagca gagctttcta atattgaaag gaaaaatcgt attttatttt
    12241 atggaaggcc tagtaaagct agaaatgctt ttcagttaat ctgtatggca ttggaaaaat
    12301 ggagcgtttt ggacgaacgt agttcaaatt gggaaatttt ttctgcagga gaagatttaa
    12361 aagatattaa attgaataat agcatagtaa taaaatcgtt agggaagatg tcagttgaag
    12421 aatacgcaaa atttatgttg gaatctaaaa tcggaatctc tctaatggcc tcaccgcatc
    12481 ctagctatcc tccgttagaa atggctacgt ttggtatgaa agtcataacg aattctttcg
    12541 ttacaaaaga tatttctgat tttaatgaaa acataatttc tattgaacat attaatatta
    12601 ataaattggc ggaagaatta cattttttaa caacatctga tatagaatat aaaatttcga
    12661 aaaacgatga ttatataaat ggtattagcc agcttgatac aattgtagat gaaattgcgg
    12721 gacatttaca atttcggcat agcgaggtgt gattgtgaaa aggaaatcca ttgcccgaaa
    12781 ttatttactt aatttgataa aaacgacctt gtctattcta tttcccctga tatcataccc
    12841 atatgtgtcg cgtattttat ctgtggatgg gctgggtgca atcaattttt caacctcgtt
    12901 tgttaattat ttcgtactaa ttgcaatctt tggaattaat gtctacgctg ttagagaagg
    12961 tgccaaatat cgagatgata aaaagttact tgggaagttt gtaacggaga tgttacttgt
    13021 tagtatttgc acggcaatga tttcattctc tttattaact gtttccttac tcctacctgc
    13081 tctatcagaa tatagaagtc ttattctaat tttttcaatt accattatat ttaatgttgt
    13141 ggggatggag tggttttttc aattgatgga agactatcaa tatataacac ttcgtgcaat
    13201 tatatttcaa attctatctt tgatattttt attcatattt gtcaaaaata ggaatgatat
    13261 ttatgtgtac gctctaatta cagttgcagc aaatgcaggt tctcaaatac tgaatttatt
    13321 tagacttaga aaagaagttg aaatatttag atataaagac tataatatta gaaattattt
    13381 taaaccgatg tttctgatat ttttaacctt attgtctatg aatatgtata gatatttaga
    13441 tgttactttt ctgggcttct ttaaaaatga tcgaagtgtg ggctactata gcttagctac
    13501 aaaaataaca agtgctataa tttcaatgtt atcttctgtt acagttattt tgacacctcg
    13561 tctagcatat cattataaga aggaggagtt tgataaattc tataaaattg cttatagttc
    13621 ctttgatttg attttattac ttgctatacc agttgttata ggtgtattta gttttagttc
    13681 tattttagta gattttttgg gtgggagtac ttttgtttct tctgtgttaa cggtggagat
    13741 attaagttta acaattctat tctctaattt gaatgcttta ttaattacac ctattttaac
    13801 ggttatgaat cgtgagaaag cggttttaaa aatttttatt atcgcattga ttttcaatgt
    13861 tattacaaac atgttactta ttccagtaat ggattttaat ggttcagctt tggttacagt
    13921 tttgacagaa ggaattattt gcatattatc tttaattagt ataaaaagtg tgtttaatgt
    13981 tagaaggcta tttaagaatc tttttcaata tctggtagct agtatcttta taattgttat
    14041 caagattgtt atttctcagt acgtttcatc aaattatatt atttttattt caactgcttt
    14101 actaagcgca attttatatt tccttacttt gatattattg agaaatgagt tagtactaca
    14161 attaataata gaagttagaa agaaaatata tagatagtgg agttaaatat aaatgtttac
    14221 catatataga gccataaaaa aataattata attattttgt cgcttcccaa gattttttat
    14281 ataaatttta aatgccttcc gttgaatcag gcggttaaac ctcctatata tgttcatttt
    14341 aatactcgat taatgattag gggagacata aaaatcattg atactcattt atcacgtttt
    14401 actattattt tggggaaaga tggctctaat catatctctc ctcatgagag tagattattt
    14461 atgatggggg gcaattaatt ctagggagaa atattctatt atctagtgga tttaatttgt
    14521 gtatagagca aggaggtacg gttaaattag gagataatgt ctcttttaac agaaattctt
    14581 cgatcttttg taaaaaacaa attaatattg gtaaaaatag tttgtttggt tggaactgta
    14641 atttacgtga taataatgga cataggatct attatcaggg gaactgtatt aagagtgagg
    14701 gagttattgt aataggagag aattgctgga taacagcaga ctcagtcatt cttaaaaata
    14761 gtgttcttcc tttttctact gtagttgcta caggtagttt agtaaataaa gagtttaatc
    14821 agagtaacat tttgatagct ggaaggcctg ctagaattat tagagacgat ataaaatggg
    14881 aaagataaga tagtaattga ttaattaggt cgtgtaattt ttaacagaga taacgaaagg
    14941 taatgggtga agtaaatgaa aattgcagtt gcaggtacag gatatgtagg actatctatt
    15001 gcagttttaa tggctcagca tcatgaggtg gtagctgttg atattatttc tgaaaaggtc
    15061 aatctgatta ataatggaaa atctccaatt aaggatgact atattgaaga atacttagca
    15121 acaaagcccc tcaacttagt ggcaacattg gatacaaatc tagcgtacca aaatgcagat
    15181 tttgttatta tagcagctcc aacaaattat gattcagaaa agaacttttt tgatacatct
    15241 gctgtagaat cagttattga aacggtgtta gagactaatc ctaacgctgt aatggtaatt
    15301 aaaagtactg ttcctgtagg ctatactcaa tcgattcgta ataaatataa aacaagtaat
    15361 attttattta gtccagaatt tttacgtgag tcaaaggctt tatatgataa tttatatcct
    15421 agccgtataa ttgttgggct tgatatggac gatgcatatt taaaggagag agccgaaact
    15481 tttgcagaac tgctacaaga aggagctgtt aaagaggcta tagaaattct ttacatggga
    15541 tttacagagg cagaagcagt caaacttttt gcaaatacat atttagcctt acgtgtttct
    15601 tatttcaatg agttggatac ttatgcagaa gttaaagggc tagataccaa agctattatt
    15661 gaaggtattg gcttagatcc acgtatcgga agccaatata acaatccttc ttttggatat
    15721 gggggatatt gccttccaaa agatagtaaa caactattgg caaactataa agatgttcca
    15781 cagaatatga taacagctat cgttgagagc aatcgtacta gaaaagattt tattgcagag
    15841 cagattttga aacttgcagg agtttcaaat aatggggaaa tttacccaaa agatgtaata
    15901 ataggccttt atcggttaac tatgaagagc aactccgata attttcgtca atcttctatt
    15961 caaggtgtta tgaaacgatt gaaggcagaa ggagcaaatg tcataattta tgagccaact
    16021 cttagtgatg acgagacgtt ttttggtagt aagattgtaa atgatttgga acactttaaa
    16081 tcaattagta atgttatcgt ggcaaatcgt tatgatgatt tgcttaaaga tgtgagtgac
    16141 aaggtttata gtcgtgatat ttttaagaga gattaggtag aagttataat gtatgattat
    16201 ttaatcattg gagctggttt gtctggtgca atctttgcgc acgaagctac aaaacgtgga
    16261 aaaaaagtaa aagtgattga taaacgtgat cacatcggtg ggaacatcta ttgtgagaat
    16321 gtagaaggta tcaatgttca taaatatggt gcccatattt tccatacttc taataaaaaa
    16381 gtttgggact atatcaatca attcgctgag tttaacaact atatcaactc acctgtcgca
    16441 aactacaaag gaagtcttta caatcttcct ttcaatatga ataccttcta tgctatgtgg
    16501 ggcacaaaaa ctccacagga agtaaaagat aagattgctg agcagacagc tgatatgaag
    16561 gatgttgagc ctaaaaatct ggaagaacag gctatcaagt tgattggtcc agatatctat
    16621 gaaaagttga ttaagggtta tactgaaaag cagtgggggc gctcagcaac ggaacttcct
    16681 ccatttatca ttaagcgtct tccagttcgt ttaacatttg ataataacta ttttaacgac
    16741 cgttaccaag gaattcctat tggtggttac aatgtcatta tcgaaaacat gcttaaagac
    16801 gttgaagttg agcttggtat tgatttcttt gctcaccgtg aagagttaga agcatcagct
    16861 gaaaaagttg tcttcacagg aatgatcgac cggtattttg actacaagca cggagagtta
    16921 gaataccgta gccttcgttt tgagcatgag attttagacg aggaaaatta tcaagggaat
    16981 gctgtagtga actatacaga gcgtgagatc ccttatactc gtatcatcga acacaaacat
    17041 tttgaatatg gaatgcagcc aaagacagtt atcacgcatg aatatccagc tgactggaag
    17101 cgtggggacg agccctacta tcctattaac gatgagaaaa ataatgctat gtttgctaaa
    17161 taccaagaag aagcagcgca gaatgataaa gttatctttt gtgggcgttt agcagactat
    17221 aaatattacg atatgcatgt ggtgattgaa cgggcgcttg aggttgtgga gaaagaattt
    17281 agtaattgaa aaacaacgaa gaaaggttgc ttatatatga aaggtattat tcttgcaggt
    17341 ggttcgggga cacgattata tcctttgact cgggctgcat caaaacaact tatgccggtt
    17401 tatgataaac ccatgattta ctatcctttg tcaaccctga tgttgactgg aataaaggac
    17461 attttgatta tctcaacacc acaggatttg ccccgtttta aggacttgct cttggatggt
    17521 tccgaatttg ggatcaagct ttcctatgcg gaacaaccta gtcccgatgg acttgctcag
    17581 gcttttatta tcggtgaaga gtttatcggt gacgatagcg ttgccttgat tttaggtgac
    17641 aatatttacc atggtcctgg tctgagcaca atgcttcaaa aagcagccaa gaaagagaaa
    17701 ggtgcgactg tttttggcta ccaagtgaag gatccagagc gttttggtgt ggttgagttt
    17761 gatacagaca tgaatgctat ttctatcgaa gaaaagccag agcaccctcg ttcaaactat
    17821 gcagttacag gaatctattt ctatgataat gatgtagtag agattgccaa aagtataaaa
    17881 ccaagccctc gtggtgaact ggaaattaca gatgtaaaca aggcttacct aggtcgtgga
    17941 gatttatccg ttgaggttat gggacgaggc tttgcttggc tggatactgg aactcatgaa
    18001 agtttattag aggcttcgca gtacatcgaa acagtccaac ggatgcaaaa tgttcaggta
    18061 gcaaacttag aagaaattgc ctatcgcatg ggttatatca gtcgtgaaga tgtattgacc
    18121 ttagcccaac cacttaagaa aaatgaatac ggacagtatc tgctccgttt gattggagaa
    18181 gcatagatga cagataattt tttcggtaag acgcttgcgg cacgcaaggt tgaagctatt
    18241 ccaggcatgt tggagtttga tatccccgtt catggagata atcgtggctg gtttaaagaa
    18301 aatttccaaa aggaaaaaat gcttccactt ggatttccag agtctttctt tgcagaagga
    18361 aaattgcaaa acaatgtatc cttctcacgt aaaaatgtcc ttcgaggcct ccacgcagag
    18421 ccttgggata agtacatctc tgtagcagat ggagggaaag ttctgggttc ttgggttgat
    18481 ctacgcgagg gtgaaacctt tgggaatacc tatcagacag taattgatgc aagcaaggga
    18541 atctttgttc ctcgaggcgt agctaatggc ttccaagttc tatcagatac agtgtcatat
    18601 agctatctgg tcaatgatta ctgggctctc gagctcaaac ccaagtatgc ctttgtgaac
    18661 tacgctgatc caagccttgg tattgaatgg gaaaatattg cagaagcaga ggtttcagaa
    18721 gcagataaac atcatcccct acttaaggat gtaaaacctt tgaaaaaaga agatttgtaa
    18781 aaaggaaaga atatgactga atacaaaaat attatcgtga caggtggagc tggctttatc
    18841 ggttctaact ttgtccatta tgtttacgag aactttccag gtgttcacgt gacagtccta
    18901 gataagttga cttatgctgg aaatcgcgcg aatattgagg aaattttagg taatcgtgtt
    18961 gagttagttg ttggtgacat tgctgatgcg gagttggtag acaagttggc tgctcaagca
    19021 gatgctatcg ttcattatgc agcggaaagc cacaatgata attcgctcaa tgatccatcg
    19081 ccatttattc atactaactt catcggaacc tatactcttt tagaagctgc tcgtaagtat
    19141 gatattcgct tccaccatgt atcgacagat gaagtttatg gggatctccc tttacgcgaa
    19201 gatttgccag gtcatggtga aagaccaggt gagaaattta cggctgaaac aaaatacaac
    19261 ccaagctctc cgtactcatc aaccaaggca gcctcagatt tgattgtcaa agcctgggtg
    19321 cgttcttttg gagtcaaggc aacgatttcc aactgttcaa ataactacgg tccttatcaa
    19381 catatcgaaa aattcatccc acgtcagatt actaacatcc taagtggtat caagccaaaa
    19441 ctttacggtg aaggtaagaa cgttcgtgat tggattcata ccaatgacca ttcttcagga
    19501 gtttggacaa tcttgacaaa agggcaaatc ggtgaaacct acttgattgg ggctgatggt
    19561 gagaagaaca ataaggaagt tttggaactt atccttaagg aaatgggaca agctgcggat
    19621 gcctatgatc atgtgactga ccgtgcagga catgaccttc gctatgcgat tgatgccagc
    19681 aagctccgtg aggagttggg gtggaaacct gaatttacca actttgaagc tgggctcaag
    19741 gcaacaatca agtggtatac agataaccaa gaatggtgga aagcagaaaa agaagctgtt
    19801 gaagccaatt atgctaagac tcaggagatt attacagtat aaaaagcagg aaatagctgc
    19861 tttttattgc tatattggga agagttacat attagaaagg tctagagatg attttaatta
    19921 caggggcaaa tggccaatta ggaacggaac ttcgctattt attggatgaa cgtaatgaag
    19981 aatacgtggc agtagatgtg gctgagatgg acattaccga tgcagaaatg gttgagaaag
    20041 tttttgaaga ggtgaaaccg actttagtct accactgtgc agcctacacc gctgttgatg
    20101 cagcagagga tgaaggaaaa gagttggact tcgccatcaa tgtgacgggg acaaaaaatg
    20161 tcgcaaaagc atctgaaaag catggtgcaa ctctagttta tatttctacg gactatgtct
    20221 ttgacggtaa gaaaccagtt ggacaagagt gggaagttga tgaccgacca gatccacaga
    20281 cagaatatgg acgcactaag cgtatggggg aagagttagt tgagaagcat gtgtctaatt
    20341 tctatattat ccgtactgcc tgggtatttg gaaattatgg caaaaacttc gtttttacca
    20401 tgcaaaatct tgcgaaaact cataagactt taacagttgt aaatgaccag tacggtcgtc
    20461 cgacttggac tcgtaccttg gctgagttca tgacctacct agctgaaaat cgtaaggaat
    20521 ttggttatta tcatttgtca aatgatgcga cagaagacac aacatggtat gattttgcag
    20581 ttgaaatttt gaaagataca gatgtcgaag tcaagccagt agattccagt caatttccag
    20641 ccaaagctaa acgtccgcta aactcaacga tgagcctggc caaagccaaa gctactggat
    20701 ttgttattcc aacttggcaa gatgcattgc aagaatttta caaacaagaa gtgagataag
    20761 tagtagaatg attttctagt ctaataaaag aggcagataa tgaactccaa aggagcttaa
    20821 gatgtacgat tatcttgttg ttggtgctgg tctctttggc gcatagcttt ggctcagttt
    20881 ctattatcgc tcacaccatc catcagaagt ttaatctgaa ggtacccaat tatcgccatg
    20941 aagaagattg ggctaggatg ggtttaccaa tcacacgtaa ggaaatctct aattggcata
    21001 tcaaggcaag tcaatactat ttagagtccc tttataacct tttacgagaa aagttgttag
    21061 aacaacctct tcttcatgcg gatgaaacct cttatcgggt tctagagagt gatagccatc
    21121 tgacctacta ttggaccttt ttgtctggga aatcagagaa acaagggatt acgctttacc
    21181 atcatgatca gcgtcggagt ggttcggtag tgcaagaatt cctaggaaat tattctgcct
    21241 atgcgatagc agtccaaagt ttaggagcaa ggcgacgcta agcttggtaa actacgaacc
    21301 gctagaagct tatcgtcaac tggaagaagc tgaacttgtt ggatgttggg cgcatgtgag
    21361 aaggaagttt tttgaagcgc cccccaagca agcggataaa tcatcgttag gagctaaagg
    21421 tttagcttat tgtgatcagt tatttgcctt ggaaagagac tgggaggctt tgctagctga
    21481 tgaacgacta cagaaacgtc aagaagagct ccaaccccta atggaagatt tctttgcttg
    21541 gtgccggcgt cagtcagttt tatcgggttc aaaactagga agggcaattg aatacagcct
    21601 caagtataaa gaaaccttta agaccatttt aaaagacgga catctggtcc tttccaataa
    21661 tctagctgaa cgcgccatta aatcattggt tatgggacgg agtaaaagag tccagtggac
    21721 tcttttagcc taagctcagt ttaaaaaagt gagggtggtt attttctcaa agttttgaag
    21781 gagctaaagc aagagctatt attatgagct tattggaaac agctaaacgt catcaactaa
    21841 atagcgagaa atatctatcc tatcttctag aatgtcttcc aaacgaggaa actctcgtaa
    21901 acaaagaggt tttagaggcc tatttaccat ggactaaagt tgtacaagaa aagtgcaaat
    21961 aagaaatctc cagattagga actatccgtg agttctctag tctggagatt tttcaatata
    22021 cttcgttatt gggcgcttac aatgatattc atattttttg caaagatgtt gtttgaaaaa
    22081 taattttcaa aaattctgaa aattctgttg acaactttct gaaaagagtc tataatggag
    22141 agaaagtttt aaaggagaaa atgatgaaaa gttcaaaact acttgccctt gcgggcgtga
    22201 cattattggc ggcgactact ttagctgcat gctctggatc aggttcaagc gctaaaggtg
    22261 agaagacatt ctcatacatt tatgagacag accctgataa cctcaactat ttgacaactg
    22321 ctaaggctgc gacagcaaat attaccagta acgtggttga tggtttgcta gaaaatgatc
    22381 gctacgggaa ctttgtgccg tctatggctg aggattggtc tgtatccaag gatggattga
    22441 cttacactta tactatccgt aaggatgcaa aatggtatac ttctgaaggt gaagaatacg
    22501 cggcagtcaa agctcaagac
//
