LOCUS       CR931716               22097 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 2427/48 (serotype 43).
ACCESSION   CR931716
VERSION     CR931716.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22097)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22097)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="2427/48"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC43_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC43_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34531.1"
                     /db_xref="GOA:Q4K2R1"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K2R1"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVP
                     WDAFCVELL"
     gene            complement(307..825)
                     /gene="tnp"
                     /locus_tag="SPC43_0002"
                     /pseudo
     CDS             complement(307..825)
                     /gene="tnp"
                     /locus_tag="SPC43_0002"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     gene            322..378
                     /gene="aliB"
                     /locus_tag="SPC43_0003"
                     /pseudo
     CDS             322..378
                     /gene="aliB"
                     /locus_tag="SPC43_0003"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            1048..2493
                     /gene="wzg"
                     /locus_tag="SPC43_0004"
     CDS             1048..2493
                     /gene="wzg"
                     /locus_tag="SPC43_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34534.1"
                     /db_xref="GOA:Q4JYU2"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JYU2"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLAIYLLLVGFLLFLIFKYNILAF
                     RYLNLVVTALVLLVAFVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTNLM
                     VDQSSSYLAAYKSLIAGDTKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVSIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQNSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTGRIDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1048..1164
                     /gene="wzg"
                     /locus_tag="SPC43_0004"
                     /note="Signal peptide predicted for SPC1904 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1252..1599
                     /gene="wzg"
                     /locus_tag="SPC43_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 1.1e-62"
     misc_feature    1777..2220
                     /gene="wzg"
                     /locus_tag="SPC43_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 2.6e-68"
     gene            2495..3226
                     /gene="wzh"
                     /locus_tag="SPC43_0005"
     CDS             2495..3226
                     /gene="wzh"
                     /locus_tag="SPC43_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34535.1"
                     /db_xref="GOA:Q4JYU1"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JYU1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKSKLFGERYKFMKKRARYFLERDLVHVVASDMHNLNKRPPYMKEAYELIS
                     KQYGERRARELFIENPRLILSDQII"
     misc_feature    2498..3106
                     /gene="wzh"
                     /locus_tag="SPC43_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 8.1e-37"
     gene            3235..3927
                     /gene="wzd"
                     /locus_tag="SPC43_0006"
     CDS             3235..3927
                     /gene="wzd"
                     /locus_tag="SPC43_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34536.1"
                     /db_xref="GOA:Q4JYU0"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4JYU0"
                     /translation="MKENKEITIDVFQLFKVLWKKKTSIILTAIVAAVLAFAVSSFVL
                     TPEYSSTTRIYVVNRNQSEKAGLTNQDLQAGTYLVKDYKEIILSQDVLEKVISNLKLE
                     KTVKELSKKIQVTVPVDTRIVSITVKNAQPEEASRIANALREVAAEKIISVTRVSDVT
                     TLEEARAALSPSSPNIRRNTLLAFLAGGAVMVVSVLLLELLDDRVKRPEDVEEVMQIA
                     LLGVVLDLNKLK"
     misc_feature    3235..3381
                     /gene="wzd"
                     /locus_tag="SPC43_0006"
                     /note="Signal peptide predicted for SPC1906 by SignalP 2.0
                     HMM (Signal peptide probability 0.987) with cleavage site
                     probability 0.704 between residues 49 and 50"
     misc_feature    3253..3669
                     /gene="wzd"
                     /locus_tag="SPC43_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 6.4e-48"
     gene            3938..4639
                     /gene="wze"
                     /locus_tag="SPC43_0007"
     CDS             3938..4639
                     /gene="wze"
                     /locus_tag="SPC43_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34537.1"
                     /db_xref="GOA:Q4JYT9"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT9"
                     /translation="MPTLAIEQKRLDFAKKAEENYNALRTNIQLSGDNLRVLSISSVK
                     PGEGKSTTSINIAWAFARAGYKALLVDADIRNSIMSGVFKSREKITGLTDFLAGTTDL
                     SHGLCDTNIENLFVIQAGPVSPNPTALLQSENFATMIDTMRKYFDYVIVDTAPIGMVI
                     DAAIITQKCDASILVTAARETKRRDILKAKEQLEQTGVPFLGVVLNKFNTEVEKYGAY
                     GGYGTYGFYGNYRKG"
     gene            4648..5289
                     /gene="wcjH"
                     /locus_tag="SPC43_0008"
     CDS             4648..5289
                     /gene="wcjH"
                     /locus_tag="SPC43_0008"
                     /note="member of homology group 61"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34538.1"
                     /db_xref="GOA:Q4JYT8"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT8"
                     /translation="MIKIYFVFKNILDRFLAFFLFITLIIIPIIPITILAIWIEDPGD
                     VFYLQDRVGLNGKKFKVIKFRSMYKDADQRIKKSINSGKTERLNFKEHSQSMTTKVGK
                     VIRKLSIDELPQLLNIIKGDMSIVGPRPLQQFEITHHILTHKEMGIALKMSKRLSVKP
                     GLLCYWQVTPNKNDMPFADRMDLDLLYIDNVSFKTDFLLILKGFFTVLMGNNS"
     misc_feature    4648..4755
                     /gene="wcjH"
                     /locus_tag="SPC43_0008"
                     /note="Signal peptide predicted for SPC1908 by SignalP 2.0
                     HMM (Signal peptide probability 0.806) with cleavage site
                     probability 0.797 between residues 36 and 37"
     misc_feature    4672..5280
                     /gene="wcjH"
                     /locus_tag="SPC43_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 1.3e-24"
     gene            5291..6082
                     /gene="wciB"
                     /locus_tag="SPC43_0009"
     CDS             5291..6082
                     /gene="wciB"
                     /locus_tag="SPC43_0009"
                     /note="member of homology group 16"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34539.1"
                     /db_xref="GOA:Q4JYT7"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT7"
                     /translation="MKNIKILVATHKKYKMPSDTNMYLPIHVGCEGKEKLGFQGDNSG
                     ENISFLNPYYCELTGLYWAWKNLECDYLGLVHYRRYFTKMTKGYNESINIDDVILNRF
                     EVEKLLENSEVIVPKKRKYYIETLYSHYAHTLDASHLDLARKMIEQKNSEYLASFDKV
                     MKQRSGYMFNMFIMKKELADDYFTWLFPILDSMYECMDLSDLTPFEARLFGRVSELLF
                     NVWLSKNNLTPTEAHFMYMEKVNLFKKGLSFLQAKFFKKKYKESF"
     gene            6093..6914
                     /gene="whaI"
                     /locus_tag="SPC43_0010"
     CDS             6093..6914
                     /gene="whaI"
                     /locus_tag="SPC43_0010"
                     /note="member of homology group 149"
                     /codon_start=1
                     /transl_table=11
                     /product="putative LicD-family phosphotransferase"
                     /protein_id="CAI34540.1"
                     /db_xref="GOA:Q4JYT6"
                     /db_xref="InterPro:IPR007074"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT6"
                     /translation="MSEIKIIQNKILEILKIFIETCEENNLTYYALGGTLLGAVRHGG
                     FIPWDDDIDIGMPREDYEKFKKIASKKFNDRYLFLSEDTPGYKKAFSVIRDTSTKIVM
                     NYSNIEQEESLWIDIFPIDGLPEKGVKRKLHEKQYLFRRMMVQLSQFNSIVNQNKTNR
                     PWQEKVIIKIAGILKIENLLSFEKAQQKYLATIKKYSITEGYAGNFTGAYKLRELVPS
                     CYFGEPVKLDFEGIKLNCPNKYKDYLKAIYGDNYMTLPPIEQRLPHQYEIVSLGE"
     misc_feature    6156..6839
                     /gene="whaI"
                     /locus_tag="SPC43_0010"
                     /note="HMMPfam hit to PF04991, LICD Protein Family, score
                     2e-53"
     gene            6921..7889
                     /gene="wciE"
                     /locus_tag="SPC43_0011"
     CDS             6921..7889
                     /gene="wciE"
                     /locus_tag="SPC43_0011"
                     /note="member of homology group 44"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34541.1"
                     /db_xref="GOA:Q4JYT5"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT5"
                     /translation="MNKLRKALNYYQDISKKRSYFPNNVLNWQLLGKFLGQIPYLIGE
                     NNARKICEKRHNVTRGFLEKEFYEFIINYEFNTCNQKNSKIIWTLWMQGYENAPELVK
                     STIDSIRKFAELNNFQFILLEENTIEKYIVFPKLIKEKMDLGVIDYTKISDILRVSLL
                     AKYGGTWVDATIYMKEEFDSSLLLQNYYTIKTGGIEDYSPNISNNRWKGFFLSGNSSL
                     FSFTRDFFFEYYSRYDIAVDYLLIDYIFDIAYKYDEKIKNQMLELEKSNHNLFWLESH
                     LGDEFDQKVWDNITETTKIFKTTYKLSEEIKSNKNNFYSKLIDRKL"
     misc_feature    7029..7871
                     /gene="wciE"
                     /locus_tag="SPC43_0011"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 1e-61"
     gene            7899..9008
                     /gene="wcrC"
                     /locus_tag="SPC43_0012"
     CDS             7899..9008
                     /gene="wcrC"
                     /locus_tag="SPC43_0012"
                     /note="member of homology group 24"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34542.1"
                     /db_xref="GOA:Q4JYT4"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT4"
                     /translation="MKKIALVKWILDDSGGGERVAVSLANELTKKYEVYLIGITTKQS
                     DLFFEINSQVKYSNFFDHRVRLSKNILKISKMLKKYFVDNEIDIAFGIGITANIFLSL
                     AGIGISTQIVLCDHTNSITDNREFSQKVQRYVGAKCADKIITLTQEDRRSYIKKYGIS
                     EEKIDYVYNWKEDGLSNVPYNDESMKIVTVGRLDYQKGYDYLVQVAKKVLKEKTGWTW
                     EIYGSGNQDEVDKIKDLIIKNDLQDKLVIKGLEKNQAMIYGDKGIYVMTSRYEGLPLV
                     LLEAQQYNLPIVSFRCPTGPNEIVEDGVNGHLIDCYDTDKMSERLLELMEDSNLRTSF
                     ANHAKDNMDKFDKDKIIQQWIDLIEEMTGGNNFES"
     misc_feature    8409..8921
                     /gene="wcrC"
                     /locus_tag="SPC43_0012"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 3.6e-35"
     gene            8998..10122
                     /gene="wcyM"
                     /locus_tag="SPC43_0013"
     CDS             8998..10122
                     /gene="wcyM"
                     /locus_tag="SPC43_0013"
                     /note="member of homology group 181"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34543.1"
                     /db_xref="GOA:Q4JYT3"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT3"
                     /translation="MKAKMLICITSLTGGGAEKSLVNFIQEFESMFEISILVYTEKNN
                     FYGSKLSHLRIDYFIRKNTPAIIEKIVNKLVKLLPPSFVNRWIIQRSIFKNEKFDYEF
                     AYMEGKPTKIIAGSSNEDSLKLAYIHCDFSKNWYSKRSFKNFKEELTCYQKFNSILAV
                     STPQKESFEEIFPKTNLEVIPNLLNIDEIKNLSKEEIELENIPYFCAIGRLELVKNFE
                     LLINAFHLFRKKYSQYHLIILGDGSLYDHLKNQINNLGESQYIKLLGFQSNPYKYIKN
                     SVGLIQSSVSESFSYVLAEAAALGIPSISTKTQGSEVMSEYFEVIQVEHTSNELAKGL
                     EKVIANNFVNVHFNFNEEAYYKFLEIFKKGSRSFEIRREI"
     misc_feature    9565..10059
                     /gene="wcyM"
                     /locus_tag="SPC43_0013"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.3e-21"
     gene            10100..11197
                     /gene="wzy"
                     /locus_tag="SPC43_0014"
     CDS             10100..11197
                     /gene="wzy"
                     /locus_tag="SPC43_0014"
                     /note="member of homology group 182"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34544.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT2"
                     /translation="MKFEEKYNTLFNIIFSLLTILYLLKFVNIDRIDGISIVILICIL
                     FLFVMHSLKYGINRLKLTSLILFFLTFILNLFNGSTFLEITYFFLLYTIILKDNKKFF
                     KIHFITLTVFVLTIILLSHIGYISNFVIYRSNGGIRNSLGFVHPNSLGLMIYSLTVCS
                     LNLFEIKRFKFFFYLFLLLMNLWILQLADSRTSGYISILVIVFCYFFDKIGKLNRPLS
                     SFFINLAITMSVLFITLMSINFEASHIFQFLNKLFTNRIFSSYVFFREYGVTLFGKRI
                     DGIVSLVQGTVIIDSGYIGLLLQKGIIFFVLFLLFIFSRIKEYSFTLREGILLISVFI
                     SLMFESYGYTVFLFPILFFDYLGKRKESINE"
     gene            11190..12068
                     /gene="wcyN"
                     /locus_tag="SPC43_0015"
     CDS             11190..12068
                     /gene="wcyN"
                     /locus_tag="SPC43_0015"
                     /note="member of homology group 204"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34545.1"
                     /db_xref="GOA:Q4JYT1"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT1"
                     /translation="MNKITVFTPTFNRGYLMNKLFHSLNSQTNKHFEWLIVDDGSIDQ
                     TGELVETFKEQANFEIRYFYQQNGGKHRAINHGLDLARGELFFIVDSDDSLTDDAIEK
                     IFNNYSGIAFNHSFAGIAFNRGFSKKRIVGETFEGTYIDCDNLHRAKHNILGDKAEVY
                     RTDILKSIKFPVVDGENFMSEVVLWNEVARRGYKLRWFNDIIYFCDYLEDGLTKNSEK
                     ILFNNPVAHQMMTKELLQIDFTLKRKFGMIYNYHKIRNQSIKQTAINLEQPLILVYMV
                     VMMARIRKIVKGVKNE"
     misc_feature    11202..11696
                     /gene="wcyN"
                     /locus_tag="SPC43_0015"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 2.7e-25"
     gene            12061..13125
                     /gene="wcrH"
                     /locus_tag="SPC43_0016"
     CDS             12061..13125
                     /gene="wcrH"
                     /locus_tag="SPC43_0016"
                     /note="member of homology group 51"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34546.1"
                     /db_xref="GOA:Q4JYT0"
                     /db_xref="InterPro:IPR016503"
                     /db_xref="UniProtKB/TrEMBL:Q4JYT0"
                     /translation="MSNLYYIHEEFGSDSTAATKAPNDLQKIFQDCKFKPLVTLKKNS
                     KIVRIFDYAFKLLLCLIRIRSNDIVIFQFPFATHGKLKNFLMKLLQYKKAKMIFLIND
                     LESLRYSGNKKNLISKEQYIKNADVIICHNQRMKEFLIENKIDSEKIVVLGVFDYLLD
                     KFNKEKASFDKTVVIAGNLSPQKSGYLTELLKNENRIKFNLYGPNFTSSTNNNDCVSY
                     KGSFSPEKIPFILEGDFGLVWDGDSILTCSGITGEYLKYNNPHKVSLFIASKIPVIIW
                     KQSALSDFVKENNIGIVVNDLIEMQEIITNMTEEQYEIFRENIEQLSKKVRQGYFTNL
                     AIEKSLSIIKNNLNNYFEED"
     gene            13127..14182
                     /gene="wcyO"
                     /locus_tag="SPC43_0017"
     CDS             13127..14182
                     /gene="wcyO"
                     /locus_tag="SPC43_0017"
                     /note="member of homology group 80"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI34547.1"
                     /db_xref="GOA:Q4JYS9"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4JYS9"
                     /translation="MKKEEYNFLKVLTILLVVLGHSTYYIIKMNFGGIDYYHYINNND
                     SIIVINFFKKITEIIYYFHMPLFMAISGAFFRIQVEKNKWQSPLELFQNKFRRLLIPF
                     IIFTILYTIPMKYISNYFIQTSIFNAIIGQLFLFGNTHLWYLYALFIIFMIAYFVLKK
                     DTGFGMLLFLFALHLMSYKINITLIKSAFQFLFYFAIGFKFEQKREVYNHLLNHTKKF
                     VYFLLIGFVVLIFMNLGIKRYSIIFSKLLEEILALYGSLVTYTIAYYLSRNTKWMNTR
                     IYQFILVNGLGIYIFSDTLNYLILKWGFIVAEDLMITPHGIILMVIFRFLVTLILSLL
                     ITLAFKKLFPKYKWLVN"
     misc_feature    13145..14164
                     /gene="wcyO"
                     /locus_tag="SPC43_0017"
                     /note="HMMPfam hit to PF01757, Acyltransferase family,
                     score 9e-05"
     gene            14220..15185
                     /gene="wcyP"
                     /locus_tag="SPC43_0018"
     CDS             14220..15185
                     /gene="wcyP"
                     /locus_tag="SPC43_0018"
                     /note="member of homology group 201"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAI34548.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JYS8"
                     /translation="MCIKKFLKKSHLTKGIYQQLQRKKNQYRLEKKFKYTGKFIDRKK
                     DSKDLCIILAGYKEFLYDDVLGRVKTFAPETMDICVLSSGIYSEKLNQICEENNWSYL
                     STEQNNISLIQNVAINLHPQAKYIYKIDEDIFITEHYFENLKEAYIFAQEGDYAPGVV
                     APLIPVNGYGHKRILQKLGLEDVYYEKFGEKSKYIAGQPRFIESNPEVAKFFWSDGEV
                     IPTIDTMNAQFSKEEKKVNPCAIRFSIGAILFERSLWELMDYFNVEFEGAGLGVDEVQ
                     ICNFCILNSKPLMVSENVVVGHLSFGPQNKAMFEYYKEHPEKFSI"
     gene            15198..16655
                     /gene="wzx"
                     /locus_tag="SPC43_0019"
     CDS             15198..16655
                     /gene="wzx"
                     /locus_tag="SPC43_0019"
                     /note="member of homology group 47"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34549.1"
                     /db_xref="GOA:Q4JYS7"
                     /db_xref="InterPro:IPR002528"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JYS7"
                     /translation="MTSYKVKSIRYNFIMNFILTVSNFIFPLLTFPYVSRVLQVEANG
                     TVAYVSSIVSYFMMIASLGIPTYGIRAAAKVRDDKRKLSTIVQELLIINVILVFLVLI
                     AYFIMLFTLQSMYVYKELFYINAIGILLNVIGVGWFFQAIEQYDYITLRSIFFRLLSL
                     AMIFLLIHSPEDYIMYAGISVFASVGSNILNFKRLFEYISFKKTETYHFKPHIKPILI
                     LFAQTLVVSIYTNLDTVMLGSMKGTYDVGLYTAATKLKGILLSVVTSLGNVLLPRMSY
                     YANNQMKDRFLEIITKALNFTLFLSLPLSVFFISVSKESILLLAGEGYLGAVIGMQFL
                     MFAVIPNALTGLLGIQVLTPLEKEKYVLLSVTSGALIDLLLNFILIPAYGVSGAAFAT
                     MIAEFVVLCVQIYYTRDLLLKRLHQIVGIRYLCSVGVSTIGIVLVKKLQLSDFLLLCV
                     EGIIFFGSYGVILVLLKDDFILDFFKIFYKKLKKI"
     misc_feature    15198..15323
                     /gene="wzx"
                     /locus_tag="SPC43_0019"
                     /note="Signal peptide predicted for SPC1919 by SignalP 2.0
                     HMM (Signal peptide probability 0.679) with cleavage site
                     probability 0.496 between residues 42 and 43"
     misc_feature    15222..16031
                     /gene="wzx"
                     /locus_tag="SPC43_0019"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.5e-57"
     gene            16694..17797
                     /gene="glf"
                     /locus_tag="SPC43_0020"
     CDS             16694..17797
                     /gene="glf"
                     /locus_tag="SPC43_0020"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34550.1"
                     /db_xref="GOA:Q4JYS6"
                     /db_xref="InterPro:IPR003953"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYS6"
                     /translation="MYDYLIVGAGLSGAIFAHEATKQGKKVKVIDKRDHIGGNIYCEN
                     VEGINIHKYGAHIFHTSNKKVWDYVNQFAEFNNYVNSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIADQTAHMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     TDLPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFANRQ
                     ELEASAEKVVFTGMIDQYFDYKHGELEYRSLRFEHEVLDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQDKTVITREYPADWKRGDEPYYPINDAKNNEMYQRYLEEAKGKDV
                     IFCGRLADYKYYDMHVVIERALNVVREELGNND"
     misc_feature    17129..17728
                     /gene="glf"
                     /locus_tag="SPC43_0020"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 9.6e-133"
     gene            17790..18815
                     /gene="wcjE"
                     /locus_tag="SPC43_0021"
     CDS             17790..18815
                     /gene="wcjE"
                     /locus_tag="SPC43_0021"
                     /note="member of homology group 18"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI34551.1"
                     /db_xref="GOA:Q4JYS5"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q4JYS5"
                     /translation="MTKNRINWIDFGKGFAIFLVVIGHVFTGLFDSGKFTSDAKWLSI
                     VIAFIYIFHIPVFFALSGYFFKSVENFKEYYYYMKKKTIVLGLPYIFYSIIHYVLQKI
                     AGGSVRVPTTLFNLINIYKEPLGVVWYLYTLWALYLVYGFLSIFIKNKNYLFMISILG
                     YIITLVYMSEIFFIKKVLAWGVIFMLGSVLKTVKFNDIRFRNIILLGIIFNIVYIYIV
                     YILFNVYGKIITDYNYPRWWIIGYTGNVILSFIIFPKIEKTSQNIFRYFSKYGEISIG
                     ILIFHSPICSMIRILMLKMGIGSVFLHIVIGIVLGWYLSILATNVLKKIPLLNIVLLP
                     QRYIKLK"
     misc_feature    17805..18776
                     /gene="wcjE"
                     /locus_tag="SPC43_0021"
                     /note="HMMPfam hit to PF01757, Acyltransferase family,
                     score 7.4e-05"
     gene            complement(18856..19017)
                     /gene="tnp"
                     /locus_tag="SPC43_0022"
                     /pseudo
     CDS             complement(18856..19017)
                     /gene="tnp"
                     /locus_tag="SPC43_0022"
                     /note="Lone member of homology group 0255"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase (fragment)"
     gene            complement(order(19073..19670,19675..20676))
                     /gene="tnp"
                     /locus_tag="SPC43_0023"
                     /pseudo
     CDS             complement(join(19073..19384,19410..19670,19675..20676))
                     /gene="tnp"
                     /locus_tag="SPC43_0023"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     misc_feature    complement(19918..20502)
                     /gene="tnp"
                     /locus_tag="SPC43_0023"
                     /note="HMMPfam hit to PF03050, Transposase IS66 family,
                     score 1.1e-08"
                     /pseudo
     gene            complement(20892..21594)
                     /gene="tnp"
                     /locus_tag="SPC43_0024"
                     /pseudo
     CDS             complement(join(20892..21344,21325..21594))
                     /gene="tnp"
                     /locus_tag="SPC43_0024"
                     /note="member of homology group 31"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase"
     misc_feature    complement(order(21325..21329,21009..21344))
                     /gene="tnp"
                     /locus_tag="SPC43_0024"
                     /note="HMMPfam hit to PF05717, IS66 Orf2 like protein,
                     score 4.3e-56"
                     /pseudo
     gene            21738..>22097
                     /gene="aliA"
                     /locus_tag="SPC43_0025"
     CDS             21738..>22097
                     /gene="aliA"
                     /locus_tag="SPC43_0025"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34555.1"
                     /db_xref="GOA:Q4K2T2"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K2T2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    21738..21824
                     /gene="aliA"
                     /locus_tag="SPC43_0025"
                     /note="Signal peptide predicted for SPC1931 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    21984..22052
                     /gene="aliA"
                     /locus_tag="SPC43_0025"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     7629 a   3019 c   4040 g   7409 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
      121 aatcttagtt ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcatat aaaaacaagg gaggactgta taaaagacag aaatcctttg
      241 ttttttataa ccaaggttta taaactttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gatgaacata aagaagcgtg tccttagtgc aggtctgact
      361 tttgcatctg ctttgctttt tgatatgagc ccatgttttc tcaataggat tgtactcagg
      421 tgagtaggga ggaagaggta aaagtttatg cccaaactcc tcgcataaaa gttctaactt
      481 acctattcta tggaatctta cattatccat aataataacc gatggtgtgg ttaatgttgg
      541 taagaaaaac ttctgaaacc atacttcaaa aaagtcgctc gtcatcgtct cttcgcaagt
      601 cattggagcg attaactcac catttgttag acctgcaacc aaagaaatcc tctgatatct
      661 tcttccagat actttgcctc ttattaactg accttttaaa gagcgaccat attctcgata
      721 aaaataaata tcgaatcctg tttcgtcaat ctaaacaggt gctaggtgct ttaaactatt
      781 aaaattctta agaaataagg ctactttttc tgggtcttgt tcataattag attgaaacta
      841 gagtagtaca cctctgcttc taaaacattg ttagaaatcg atttaactgt cctgatcgat
      901 ttatcctatt cttgtttcaa tctactatat ttttgtttcg cgggaagtct acttaagata
      961 cttaaagatg cagatagtaa aaaagatgta gacattaccg taaaaaagtg atataatcgt
     1021 atgatattga atgtataggt gttaatcatg agtagacgtt ttaaaaaatc acgttcacag
     1081 aaagtgaagc gaagtgttaa tatagttttg ctggctattt atttattgtt agttggtttt
     1141 ttattgttct taatctttaa gtacaatatc cttgctttta gatatcttaa tctagtggta
     1201 actgcgttag tcctactagt tgcctttgta gggctactct tgattatcta taaaaaagct
     1261 gaaaaattta ctatttttct gttggtgttc tctatccttg tcagctctgt gtcgctcttt
     1321 gcagtacagc agtttgttgg actgaccaat cgtttaaatg cgacttctaa ttactcagaa
     1381 tattcgatca gtgtcgctgt tttagcagat agtgagatcg aaaatgttac gcaactgacg
     1441 agtgtgacag caccgactgg gactgataat gaaaatattc aaaaactact agctgatatc
     1501 aagtcaagtc agaataccaa tttgatggtc gaccagagtt cgtcttactt ggctgcttac
     1561 aagagtctga ttgcaggtga caccaaggcc attgtcttaa atagtgtctt tgaaaatatc
     1621 atcgagtcag agtatccaga ctacgcatcg aagataaaaa agatttatac caagggattc
     1681 actaaaaaag tagaagctcc taagacgtct aagaatcagt ctttcaatat ctatgttagt
     1741 ggaattgaca cctatggtcc tattagttcg gtgtcgcgat cagatgtcaa tatcctgatg
     1801 actgtcaatc gagataccaa gaaaattctc ttgaccacaa cgccgcgtga tgcctatgta
     1861 tcaatcgcag atggtggaaa taatcaaaaa gataaattga ctcatgcggg catttatgga
     1921 gttgattcgt ccattcacac cttagaaaat ctctatggag tggatatcaa ttactatgtg
     1981 cgattgaact tcacttcgtt tttgaaattg attgatttat tgggtggaat tgatgtttat
     2041 aatgatcaag aatttactgc ccatacgaat ggaaagtatt accctgcagg caatgttcat
     2101 cttgattcag aacaggctct cggttttgta cgtgaacgct actcactagc cgatggagac
     2161 cgtgaccgtg gtcgcaacca gcaaaaggtc attgtggcta tccttcaaaa attaacgtca
     2221 accgaagcac tgaaaaatta tagcacgatc attgatagct tgcaaaattc tatccaaaca
     2281 aatatgccac ttgagaccat gataaatttg gtcaatgctc agttagaaag tggtggaact
     2341 tacaaagtga attcgcaaga cttaaaaggt acaggtcgga ttgatcttcc ttcttatgca
     2401 atgccagaca gtaacctcta tgtgatggaa atagatgata gtagtttagc tgtagttaaa
     2461 gcagctatac aggatgtgat ggagggtaga tgaaatgata gacatccatt cgcacatcgt
     2521 ctttgatgta gatgatggtc ccaagtcaag agaggaaagc aaggctctct tggcagaatc
     2581 ctacaggcag ggggtgcgaa ccattgtctc tacctctcat cgtcgcaagg gcatgtttga
     2641 aactccggaa gagaagatag cagaaaattt tcttcaggtt cgggaaattg caaaagaagt
     2701 agcagatgat ttagtcattg cttatggcgc agagatatac tatactctgg atgctctaga
     2761 aaagctagaa aaaaaagaaa ttcctaccct taatgatagt cgttatgcct tgattgagtt
     2821 tagcatgcat acttcctatc gtgagattca tacgggattg agcaatattt tgatgttggg
     2881 aatcacgcca gtcattgccc acatcgagcg ttatgatgct ctagagaata acgaaaaacg
     2941 tgttcgtgag ctgattgata tggggtgcta tactcagata aatagttatc atgttttaaa
     3001 atctaagctc tttggtgaaa gatataaatt tatgaaaaag agagctcggt attttttgga
     3061 acgtgattta gttcatgtag ttgcaagtga catgcacaat ttgaacaaac gtccccctta
     3121 tatgaaagaa gcctatgaac ttatctcaaa acaatacggt gaaagaagag cgagagaatt
     3181 atttattgaa aatcctcgct taatcttatc tgatcaaatt atttaggagt tgacatgaaa
     3241 gaaaataaag aaattacgat tgatgttttt caattgttta aagtcctttg gaagaagaaa
     3301 acctctatta tactaactgc gattgtagca gctgtcctag cttttgctgt aagtagtttt
     3361 gtactgacac ctgagtattc tagtacgaca cgtatttatg tggtcaatcg aaatcaatcg
     3421 gaaaaagcag ggttgacgaa ccaggatttg caggctggaa cctatctggt aaaggactat
     3481 aaggaaatca tcctctctca agatgtactt gagaaagtca tttcaaatct taaactagag
     3541 aaaacagtta aggaattaag caagaagatt caggtaacag tacctgtgga tactcgtatc
     3601 gtatcaatta ctgtaaaaaa tgcacaacca gaagaagcta gccgtatcgc aaatgctctt
     3661 cgtgaagtgg ctgctgaaaa aatcatttct gtaactcgtg tatctgatgt gacaacattg
     3721 gaagaagcca gggcagccct aagtccttca tcacctaata ttcgtcgtaa taccctgtta
     3781 gcttttttag cgggaggagc agtgatggta gtttcagtct tgttacttga gttgttggat
     3841 gatcgtgtta aacgaccaga agatgtggaa gaagtaatgc agattgcact tctaggggtt
     3901 gttctagatt tgaataagtt aaaataaggg agaaaatatg ccaacattag caatagaaca
     3961 aaaacgttta gattttgcga aaaaagcaga agagaattac aatgctttgc gaacaaatat
     4021 tcaattgagt ggtgataatc tgagagttct ttccatctcg tctgttaaac ctggtgaggg
     4081 gaaatcgaca acatcaataa atattgcttg ggcctttgcg cgtgcaggct ataaagcttt
     4141 attggtggat gcggatattc gtaattctat catgtcagga gtctttaaat caagagaaaa
     4201 aattactggg ctaacggatt ttctggcagg taccactgac ctttctcatg gactttgtga
     4261 tacaaatatt gaaaatttat ttgttattca ggcaggacct gtatccccta acccaacagc
     4321 acttttacag agtgaaaact ttgccactat gattgatact atgcgtaagt attttgatta
     4381 tgtcattgtc gatactgcac cgattgggat ggtcattgat gctgctatta tcacacaaaa
     4441 atgtgatgct tctattttgg taacagcagc gagggaaaca aagcgtcgtg atattttgaa
     4501 agcaaaggaa cagttagaac agacaggagt acctttttta ggagttgttc taaataaatt
     4561 caatacagaa gttgaaaaat atggagctta tggtggctat ggaacttatg gtttctatgg
     4621 aaattatagg aagggatgac ggagtaattg ataaaaatat attttgtttt taaaaatatt
     4681 ttagatagat ttttggcgtt tttcctattt attactttga taatcatacc gattattcct
     4741 ataacaattt tggctatttg gatagaagat ccaggagatg ttttctattt acaagataga
     4801 gttggtttaa atggaaaaaa attcaaagta ataaagttcc ggagcatgta taaagatgcc
     4861 gatcagagaa taaagaaaag tattaatagt ggtaaaactg agcgtctaaa ttttaaagaa
     4921 cattctcaaa gtatgactac aaaagtcggt aaagtgatac gcaaactttc aattgatgaa
     4981 ttacctcaat tattgaatat tataaaaggt gatatgtcta tagtcggacc tcgtccatta
     5041 caacagtttg aaatcactca tcatattctt acccataaag aaatgggtat tgctttaaag
     5101 atgtctaaaa gattgtctgt gaaacctggt ttgctttgtt attggcaagt tacgccaaat
     5161 aaaaatgaca tgccttttgc tgacagaatg gatctcgatt tattatatat tgataatgta
     5221 tctttcaaga ctgatttctt gcttatttta aagggttttt ttacagtttt aatgggtaat
     5281 aatagttaac atgaagaata taaaaatatt agtagcgaca cataaaaaat ataaaatgcc
     5341 cagtgataca aatatgtatc taccaattca tgtaggatgt gaaggaaagg aaaaattagg
     5401 atttcaaggt gataattctg gcgaaaatat ttctttttta aatccttact actgtgaact
     5461 tactggtctc tattgggcat ggaaaaattt agagtgcgac tatttaggtt tggtacacta
     5521 tcgtcgttat tttactaaaa tgactaaagg gtacaatgaa tcaataaata ttgatgatgt
     5581 aattttaaat aggtttgaag tggagaaatt gttagagaac tcagaagtca tcgttcctaa
     5641 aaaaagaaag tactatatag aaaccctcta ttctcactat gctcatacct tggatgctag
     5701 ccacttagac ctagctagaa aaatgattga acagaaaaat tctgaatatc tagcaagttt
     5761 tgataaggta atgaagcaga gaagtggcta tatgttcaat atgtttatta tgaaaaaaga
     5821 actagccgat gattatttca cttggctatt tccaatttta gatagcatgt atgaatgtat
     5881 ggatttatca gacttaactc cttttgaagc ccgtcttttt ggaagagtaa gtgagttgtt
     5941 atttaatgta tggttgtcga agaataactt gactcctacg gaagcacatt ttatgtatat
     6001 ggaaaaagta aatctattta agaaaggttt atcattccta caagcgaagt ttttcaaaaa
     6061 gaaatataaa gaaagtttct agaggaggaa atatgtctga gataaaaata attcaaaata
     6121 aaattttaga aatacttaaa atttttatcg aaacatgcga agaaaataac ttgacgtatt
     6181 atgcactagg tggaacatta ttaggagccg ttaggcatgg tggattcatt ccttgggatg
     6241 atgatataga cattggtatg cccagagaag attatgagaa atttaaaaaa atagctagca
     6301 aaaaatttaa tgatagatat ctatttttga gtgaagatac tccaggttat aaaaaagctt
     6361 tttctgtaat tcgagatact tcaacaaaga ttgttatgaa ttatagtaat atagagcaag
     6421 aggagagttt gtggatagat atatttccta ttgatggtct acctgaaaaa ggtgtgaaga
     6481 gaaaactaca cgagaaacag tacctattta gaagaatgat ggtacagtta tctcaattca
     6541 attcaatagt gaatcaaaat aaaaccaaca gaccttggca agagaaagta ataattaaaa
     6601 ttgcagggat tttaaaaatt gaaaatttac tgtcttttga aaaagcgcaa caaaagtatc
     6661 tagctactat aaagaaatac agtataacag agggttatgc aggtaatttt acaggggcat
     6721 ataaacttcg tgagttagtg ccaagttgtt attttggtga acctgttaaa ttagattttg
     6781 aaggaataaa actgaactgt ccaaataaat ataaagatta tctcaaagca atatatggtg
     6841 ataattatat gacattacct ccaattgaac aaagacttcc ccatcaatat gaaattgtta
     6901 gtttaggaga atgatgataa atgaataaat taagaaaagc tttaaattat tatcaagaca
     6961 taagcaaaaa aagatcatat tttcctaata atgtactaaa ttggcaattg ttaggaaagt
     7021 ttcttggaca aataccatat cttataggag aaaataatgc gagaaaaatt tgtgaaaaaa
     7081 ggcacaatgt aacaagagga tttttggaaa aagaatttta tgaatttata ataaattatg
     7141 aatttaacac ttgtaatcaa aaaaatagta aaattatttg gacattgtgg atgcaaggat
     7201 atgaaaatgc gccagaatta gtaaaaagta caatcgatag tataagaaaa tttgctgaat
     7261 taaataattt tcagtttata ttgttagaag agaatacgat agaaaaatat atagtatttc
     7321 ctaagctgat aaaggagaaa atggatttag gtgttataga ttatactaaa atttcggata
     7381 tattaagagt ttcattgctg gcaaaatatg gagggacatg ggtagatgcg actatatata
     7441 tgaaagaaga gtttgattca tcattattat tacagaatta ttatactata aaaacaggag
     7501 gaatagagga ttattctcct aatatttcga ataataggtg gaaaggtttt tttttatcag
     7561 gtaatagttc attatttagc tttactcgtg attttttctt tgaatattat agcagatacg
     7621 atatcgctgt agattattta ttgatagatt atatttttga tatagcttac aaatacgatg
     7681 agaagattaa aaatcaaatg cttgaattag aaaaatctaa tcataattta ttttggttag
     7741 aaagtcattt aggagatgag tttgatcaaa aagtgtggga taatattaca gaaactacta
     7801 aaatattcaa aacaacgtat aaattatctg aagaaattaa atcaaataag aataattttt
     7861 attccaaact aatagataga aagttataga acgagaaaat gaagaaaata gctttagtga
     7921 aatggatttt ggatgattct ggtggtggtg agcgagttgc tgtatctttg gcaaacgaac
     7981 ttacaaaaaa gtatgaagtt tatttaattg gaattacaac aaagcaatcg gatttattct
     8041 ttgaaatcaa ttctcaagta aaatactcca atttttttga ccatcgagta cgcttgtcta
     8101 agaatattct aaagatctca aaaatgttaa aaaaatattt tgtagataat gagatagata
     8161 ttgcctttgg aatagggata actgctaata tatttttatc tttggcagga ataggaatat
     8221 ccacccaaat agttttgtgt gaccatacaa attcaattac agacaataga gaattttctc
     8281 agaaagtcca aagatatgtt ggagcaaaat gtgcagacaa gattatcact ctcacacaag
     8341 aagatcgtag aagttatata aaaaaatatg gtatttctga agaaaaaatt gattatgtct
     8401 ataattggaa agaagatggt ctttccaatg taccttataa tgatgagtca atgaaaattg
     8461 ttacagtagg tcgtttggat tatcaaaaag gctatgatta tcttgttcaa gttgctaaga
     8521 aagtactgaa agaaaagact ggctggactt gggaaattta tggttctggt aatcaagatg
     8581 aggtagataa aatcaaggat ttaatcatca aaaatgattt gcaagataag ttagtcatta
     8641 aaggtcttga aaaaaatcag gctatgattt atggagataa aggaatttat gtcatgactt
     8701 ctcgttatga aggattaccc ttggtattgt tagaagctca acaatacaat cttcctattg
     8761 ttagcttcag gtgtccaacg ggacctaatg agattgttga agatggggtc aatggtcatc
     8821 taatagattg ttatgatacc gataagatga gtgagagact acttgaattg atggaagatt
     8881 cgaacttgcg aacttccttc gccaatcatg ccaaggataa tatggataaa tttgataaag
     8941 ataaaataat tcaacagtgg attgatttaa ttgaggaaat gactggaggg aataattttg
     9001 aaagctaaaa tgttaatttg tataactagt ttaacaggtg gaggagctga aaaatcactt
     9061 gttaacttta ttcaagaatt tgaaagtatg tttgaaatta gcattctagt atatacggaa
     9121 aaaaataatt tttatggctc aaaattaagt catttaagga ttgattattt tattagaaag
     9181 aatacaccag ctattattga aaaaatagtg aataagcttg ttaagttatt accaccgtca
     9241 tttgtgaata gatggattat acagagaagt atttttaaaa atgaaaaatt tgattatgaa
     9301 tttgcatata tggaaggaaa acctacaaaa atcatagcgg gatcatcgaa tgaagatagc
     9361 ttaaaactgg cttatatcca ttgcgatttc tcaaaaaatt ggtattcaaa acgatcgttt
     9421 aaaaatttta aagaggaatt gacttgttat caaaagttta attcaatctt agctgtttct
     9481 actccacaaa aagaatcctt tgaggagatt tttccaaaga caaatttaga agtaatccct
     9541 aacttgctta acattgatga aataaaaaat ttaagtaaag aggaaataga attagaaaat
     9601 attccttatt tttgtgcgat aggaagatta gaacttgtta aaaattttga attattaata
     9661 aatgcttttc atttatttag aaaaaagtat tcacaatatc atttaattat tttgggagat
     9721 ggtagtttat atgatcattt aaagaatcaa attaacaatc taggagagag ccaatatata
     9781 aaattattag gttttcaatc taatccatat aaatatataa agaatagtgt gggattaatt
     9841 caaagttcag tatcagagtc ttttagttat gtattagcag aagcagctgc tttaggcatt
     9901 cctagtattt caacaaaaac tcaaggttct gaggttatgt cagaatattt cgaagtaatc
     9961 caggtagagc atacgagtaa cgaattagca aaagggctag agaaagtcat tgcgaacaac
    10021 tttgttaacg ttcattttaa ttttaatgaa gaagcttatt acaaattttt agagatattt
    10081 aagaaaggaa gtagaagttt tgaaattcga agagaaatat aacacattgt tcaatataat
    10141 tttttctctg ttaacaatat tgtatctact gaaatttgta aatattgaca gaattgatgg
    10201 aatttctatt gtaatcctta tatgtatatt attcctgttt gtgatgcata gtcttaaata
    10261 tggaataaat agattaaaac taacttcctt aatattgttt tttttaacat ttattttgaa
    10321 tctttttaat ggttctacat ttctagaaat aacgtacttc ttcttattat atacaattat
    10381 attaaaagat aataaaaaat ttttcaaaat acattttatt acacttacag tattcgtgtt
    10441 aacaattata ttattgtccc atattggcta tattagtaat tttgtgatat atagatcaaa
    10501 tggtggtatt aggaatagtt taggatttgt acacccgaat tcattagggt taatgatcta
    10561 ttccttaacc gtttgtagtt taaatctttt tgaaataaaa agattcaaat tcttcttcta
    10621 tttattttta ttattgatga atttatggat attacagtta gcagactcta gaacatcagg
    10681 atatataagt attttagtaa ttgtcttttg ttactttttt gataaaatag gtaagttaaa
    10741 tagaccgttg agtagttttt ttattaattt ggctattaca atgtctgttt tgtttataac
    10801 tttaatgtca attaattttg aagccagtca tattttccaa ttcttaaata aattgttcac
    10861 taatcgaatt tttagtagtt atgtattttt tagagaatat ggggttactc tatttggcaa
    10921 aagaattgat ggaattgtct cattagttca aggaacagtc ataattgaca gtggttatat
    10981 aggattgcta ttacaaaaag gaattatttt ttttgtgtta tttttgctat ttattttttc
    11041 tagaataaaa gaatactcat ttacactaag agaaggtatt ctactgatta gtgtatttat
    11101 ttctcttatg tttgagagct atggttacac cgtatttcta ttcccaatat tattttttga
    11161 ttatttagga aaaaggaagg aaagtattaa tgaataaaat taccgtattt acaccaactt
    11221 ttaatagagg gtatttaatg aataagttgt ttcattcatt aaacagtcaa acaaataaac
    11281 attttgaatg gcttattgta gatgatggtt caatagatca gactggtgag cttgttgaaa
    11341 catttaagga acaggcaaat tttgaaatac gatattttta tcaacaaaat ggtggtaagc
    11401 atagagcaat taatcatggt ttggatttag ctagagggga gttattcttc atcgttgatt
    11461 ccgatgattc attgacagat gatgctattg agaaaatttt taataactat tctggaattg
    11521 cctttaatca tagttttgca ggcatagcat ttaatagagg tttctctaaa aaaagaatag
    11581 ttggagagac ttttgaagga acatatatag attgtgacaa tttacatcga gctaaacata
    11641 atattttagg agataaggca gaagtatatc gaacagatat tttaaagagt attaagtttc
    11701 cagtggtaga tggagaaaac tttatgagtg aagttgtctt atggaatgaa gttgcaagaa
    11761 ggggttataa attacgttgg tttaatgaca taatttattt ttgtgactat ttagaagacg
    11821 gattaaccaa aaatagtgaa aaaattttat ttaataaccc agttgcacat caaatgatga
    11881 ccaaggaatt gttacaaatt gattttacat taaagagaaa atttgggatg atctataatt
    11941 atcataaaat tagaaaccaa agtattaagc aaactgctat taatcttgaa cagcctctaa
    12001 ttttagtata tatggtagta atgatggcta gaattagaaa aattgttaag ggggtgaaaa
    12061 atgagtaact tatattatat tcatgaagag tttggtagtg attcaacggc ggctacaaaa
    12121 gcaccaaatg atttacagaa aatatttcaa gactgtaaat ttaaaccatt agtaacatta
    12181 aaaaaaaata gtaaaatagt aagaatattt gattacgcgt ttaaactttt gttgtgtctt
    12241 attagaatta gaagtaatga tattgtgata tttcaatttc cttttgctac tcatgggaaa
    12301 ctaaaaaatt ttttaatgaa attactacaa tataaaaaag ctaaaatgat ctttttaata
    12361 aacgatttag agtcgttaag atattcggga aataaaaaaa atctaatttc taaggaacag
    12421 tatattaaaa atgctgatgt gattatttgt cataaccaac gaatgaagga gtttttaata
    12481 gaaaataaga ttgacagtga aaaaatagtt gtactcggtg tttttgatta tttactggat
    12541 aagtttaata aagaaaaagc atcttttgat aaaacagttg taattgcagg gaatctttcg
    12601 cctcaaaaaa gtggttattt aactgagtta ttaaaaaatg aaaatagaat aaaatttaat
    12661 ttatatggac ctaattttac ttcatcgact aacaataatg attgtgtatc atataaagga
    12721 agtttttcgc ctgaaaaaat tccttttata cttgaaggtg attttggatt agtttgggat
    12781 ggcgattcta tattaacttg ttcagggatt actggggagt atttgaaata caataatcct
    12841 cataaagtgt cgttatttat agcttcaaaa ataccagtta ttatttggaa acaatctgcc
    12901 ttgagtgatt ttgttaaaga aaataatatt ggaattgtag taaatgattt aattgaaatg
    12961 caagagatta ttactaatat gactgaagag caatatgaga tttttagaga aaatattgaa
    13021 cagttgtcca aaaaggtaag gcaaggctat tttacgaatt tagcgattga aaaatcttta
    13081 agcataataa aaaataatct caataattat tttgaggaag attgatatga aaaaagaaga
    13141 atataatttt ttaaaagtcc tcacaatatt attagtagta ttaggacata gtacgtatta
    13201 tattattaag atgaattttg gtgggattga ttattatcac tatataaata ataatgattc
    13261 aattatagta ataaattttt tcaaaaaaat aacagagatt atctattact ttcatatgcc
    13321 tttatttatg gcaatatctg gagcattttt cagaattcaa gttgaaaaaa ataagtggca
    13381 aagtccttta gagttattcc agaacaaatt tagaagacta ttaatcccat ttattatttt
    13441 tacgattttg tatactattc ctatgaaata tatttcaaac tattttatac aaacgagtat
    13501 ctttaatgcg attattggtc aactgttttt atttgggaac actcatctgt ggtatttata
    13561 tgcattgttc attattttta tgattgccta cttcgttttg aaaaaagata cgggttttgg
    13621 aatgttactg ttcctatttg cacttcattt aatgagttac aaaattaata ttacgttaat
    13681 aaaaagtgcg tttcaatttt tattttattt tgcgattggt tttaaatttg aacaaaaaag
    13741 agaagtatac aatcatttat tgaatcatac caagaaattt gtatattttc ttttaatcgg
    13801 atttgttgtg ttaattttca tgaatttggg tattaagaga tactcaatta ttttttcaaa
    13861 gctacttgaa gaaattttag cattgtatgg aagtttggta acttatacta ttgcttatta
    13921 tttatcaaga aacacgaaat ggatgaatac cagaatatac cagtttattt tagtcaatgg
    13981 tctaggaatt tatatttttt cggatactct taattatttg atattaaagt ggggctttat
    14041 tgttgctgag gatttaatga ttacacctca tggaattatt ttgatggtaa tttttcgatt
    14101 tttggtaaca ttaattttaa gtttgctgat tactttagca tttaaaaaac tatttccgaa
    14161 gtataaatgg ttagtgaatt aaaaaatttt atagagcgta aaaacgtaaa ggagaaaaaa
    14221 tgtgtattaa aaagtttctt aaaaagagtc atctgaccaa aggaatttat caacaattac
    14281 aaagaaaaaa gaatcaatat cgcttagaaa aaaaatttaa atatacaggg aaatttattg
    14341 accgtaaaaa agatagtaaa gatttatgta tcatattagc ggggtataaa gaatttttat
    14401 atgacgatgt gctaggaaga gtaaagacat ttgcaccaga aacaatggat atttgtgtcc
    14461 tatcttctgg catctattca gaaaaattaa accaaatttg tgaagaaaat aattggtcgt
    14521 atttgagtac ggaacagaac aatatatctt taattcaaaa cgtagctatt aatctacatc
    14581 ctcaagcaaa atatatttat aaaattgatg aagatatttt tattacagaa cattattttg
    14641 aaaatttaaa agaagcatat atttttgcac aagaagggga ttatgcaccc ggtgtagtag
    14701 caccactcat tccggttaat ggttatggac ataaaagaat cttacaaaaa ttaggcttgg
    14761 aagatgttta ttatgaaaaa tttggagaaa aatcgaaata tatagctgga cagcctcgtt
    14821 ttatagagag taatcccgaa gtagcgaagt ttttctggag cgatggagaa gtaattccta
    14881 ctatagatac aatgaatgca caattttcaa aagaagagaa aaaagtgaat ccgtgtgcaa
    14941 ttcgcttcag tatcggtgca attttatttg agagaagctt atgggaactg atggattatt
    15001 ttaatgttga gtttgaggga gctggacttg gagtggatga agtccaaatt tgtaattttt
    15061 gcatcttaaa ttcaaaacca ttgatggtca gtgaaaatgt ggttgtggga catttatcgt
    15121 ttggtcctca gaataaggct atgttcgaat attataaaga acatccagaa aaattttcta
    15181 tttagatgag ggataatatg acaagttata aagttaaatc tatcaggtat aattttataa
    15241 tgaattttat tttgactgtt tcaaatttca tctttccatt gttaactttt ccctatgttt
    15301 ctagagtact tcaagttgag gcgaatggta ctgtagcata tgtatcatct attgtatctt
    15361 attttatgat gattgcttca cttggtattc caacgtatgg catacgtgct gcagcaaaag
    15421 tacgtgatga taaaagaaaa ttatctacca ttgtccaaga actattgatt attaatgtaa
    15481 ttcttgtatt cttagtactc attgcatatt ttataatgtt gtttacttta cagtcaatgt
    15541 acgtctataa agaattattc tatatcaatg caataggtat actattaaat gtcataggag
    15601 ttggttggtt ttttcaagca attgaacaat atgattatat tactcttaga tcgattttct
    15661 tcagactttt atcattagct atgattttct tacttatcca tagtcctgag gattatatta
    15721 tgtatgcagg aatttctgtt tttgctagtg tgggatcaaa tattttaaat tttaaacgat
    15781 tatttgaata tatatcattt aaaaagacag aaacttatca ttttaaacca catataaagc
    15841 cgattttgat tttatttgct cagacattgg tagtgtcgat ttatacgaat cttgataccg
    15901 ttatgctagg aagtatgaaa ggaacatatg atgtgggatt atatactgca gcaacaaaac
    15961 taaaggggat tctcttgagt gttgttactt cattaggaaa tgttttgctt ccaagaatgt
    16021 cctactatgc taataatcaa atgaaagatc ggtttttgga aatcataaca aaagctttga
    16081 actttacgtt attcttatcg cttccattgt cagtattctt tatttcagta tcaaaggaaa
    16141 gtattttgct acttgctggg gaaggatatt taggtgctgt tataggaatg caatttttaa
    16201 tgtttgcagt tattcctaat gcacttacgg gtttattagg tattcaagta ttaacacctt
    16261 tagaaaaaga aaagtacgta ttactttcag tgacttcagg agcgttaata gatttactac
    16321 taaacttcat tttaattcca gcttatggtg taagtggagc agcatttgcc actatgattg
    16381 cagaattcgt tgtattatgc gttcagattt actatacgag agatttgcta ttaaagaggc
    16441 tacatcaaat agttggcatt agatatctat gctcggtagg ggtgagtact attggaattg
    16501 ttcttgtaaa gaaattacaa ttaagtgatt ttttgttatt atgtgtggaa ggaatcattt
    16561 tctttggaag ttacggtgtg attctagtgt tgttaaagga tgatttcatt cttgattttt
    16621 ttaaaatttt ctataagaaa ttaaagaaaa tttaactaat taattttgaa aatttaattt
    16681 taaaggagaa aaaatgtacg attatcttat tgtcggagct ggattgtcag gtgcaatctt
    16741 tgctcatgaa gcaacaaaac aaggaaaaaa agtaaaagta atagataaac gtgaccacat
    16801 tggtgggaac atctattgtg agaacgttga aggaatcaat atccataagt atggtgccca
    16861 tatcttccat acctctaata aaaaagtttg ggactatgtc aatcaattcg ctgagtttaa
    16921 caactatgtc aactcacctg tcgcaaacta caaaggaagt ctttataatc ttcctttcaa
    16981 tatgaatacc ttctatgcga tgtgggggac aaaaactcct caagaagtca aggataagat
    17041 tgctgatcaa acggctcaca tgaaggacgt tgaacctaaa aacttggaag aacaggctat
    17101 caagttgatc ggtccagata tctatgaaaa gttgatcaaa ggctacactg aaaagcaatg
    17161 gggacgttct gcgactgacc ttccaccgtt tatcatcaaa cgtctaccag ttcgtttgac
    17221 ttttgataat aactacttca atgaccgtta ccaaggaatt ccaatcggtg gttataatgt
    17281 cattatcgaa aatatgttga aggatgtgga agtagaactt ggagttgact tttttgccaa
    17341 tcgtcaagaa ttagaggctt ctgctgaaaa ggttgtcttt acaggaatga ttgaccaata
    17401 ctttgattat aaacatggtg agttagaata ccgtagtctt cgttttgagc atgaagttct
    17461 tgatgaagag aactatcaag gaaatgcagt tgtaaactat acagaacgag aaattcctta
    17521 tactcgcatt attgagcata aacattttga gtatggtacg caagataaaa cggttattac
    17581 tcgtgaatac ccagctgatt ggaaacgtgg agatgaacca tactacccaa tcaacgacgc
    17641 taaaaataat gaaatgtatc aaagatattt agaagaagca aaaggtaaag atgttatctt
    17701 ctgtggtcgt cttgcagatt ataaatatta tgatatgcac gtagtaatcg aaagagctct
    17761 taatgtagta agagaggaat taggtaataa tgactaaaaa tagaataaac tggatagatt
    17821 ttgggaaagg gttcgcaata tttctagtag tcataggtca tgtgtttact ggtttatttg
    17881 attctgggaa atttacaagt gatgccaaat ggttatccat agttattgca tttatatata
    17941 tattccatat tccagtattc tttgctttat caggatattt tttcaaatct gtagagaatt
    18001 ttaaagagta ttattattat atgaagaaga aaacgatagt attaggatta ccgtatatat
    18061 tttattctat aattcattat gtattacaga aaatagcggg aggatcggta cgtgttccca
    18121 ctacattgtt taatttgata aatatttata aagaaccatt aggagttgta tggtatttgt
    18181 atacattatg ggcactatat ttagtatacg gatttttatc aatatttata aagaacaaaa
    18241 actatctttt tatgattagt atactcggat atataattac attagtatat atgtcagaaa
    18301 tattttttat aaaaaaagtt ctagcatggg gagtaatttt catgttgggt tctgtattaa
    18361 aaacagttaa atttaatgat attagattta gaaacataat tctactagga atcatattta
    18421 atatcgtata tatttatata gtgtatattt tatttaatgt atatggtaaa ataataacgg
    18481 actataacta tcctagatgg tggattattg gatacacagg taatgttatc ttatcattta
    18541 taatttttcc aaaaatagaa aaaacatccc aaaatatttt taggtatttt agtaaatatg
    18601 gggaaattag tatagggatt ctaattttcc attcaccaat ttgtagtatg attcgaattc
    18661 taatgttaaa aatgggaatt ggttctgttt ttcttcatat tgttattggt attgtcttgg
    18721 gctggtattt atcaatactt gcaaccaatg tattgaagaa aattccatta ttgaatattg
    18781 ttttactacc acagagatat attaaactaa aataaaaagg ctctttgtca actgtagtgg
    18841 gttgaagaaa agctaagctc gagaaaggac aaattttgtc ctttcttttt tgatattcag
    18901 agcgataaaa atccgttttt tgaagttttc aaagttccga aaaccaaagg cgttgcgttt
    18961 gaggaattta atgagattat tagtcgcttc taatgtaacc gcccaataac gaagtctatt
    19021 gaaaaatctc cagactagag aactcatata tagttcctaa tctggagatt tcttatttgc
    19081 acttttcttg tacaacttta gtccatggta aataagcctc taaaacctct ttgtttacga
    19141 gagtttcctc gtttggaaga cattctagaa gataggatag atatttctcg ctatttataa
    19201 tggattgaaa taagatatga acaaattgat taggaaagga aaattgattt atagaaatgt
    19261 tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga cgtttagctg
    19321 tttccaacaa gctcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata
    19381 accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac tcttttactc
    19441 cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt
    19501 ccgtctttta aaatagtctt aaaggtttct ttatacttga ggctgtattc aattgccctt
    19561 cctagttttg aacctgctaa aactgactga cgacggcacc aagcaaagaa gtcttccatt
    19621 aggggttgga gctcttcttg acgtttctgt agtcgttcat cagctgacaa tgtcctccca
    19681 gtctctttcc aaggcaaata actgatcaca ataagctaaa cctttagctc ctaaggatga
    19741 tttatctgct tgcttggggg tcgcttcaaa aaatttcctt ctcacatgcg cccaacatcc
    19801 aacaagttca gcttcttcca gttgacgata agcttctagc ggttcgcagt ttaccaagct
    19861 tagcgtcgcc ttgctcctaa accttggact gctatcgcat aggcagaact agaggactaa
    19921 agtcctaagt tactgccgca acatatcaca atgaacatag ccagaataat ctcctaggaa
    19981 ttcttgtact accgaaccac tccgactctg atcatgatgg tacagcgtga ttgcttgatt
    20041 ctcaactttc ccagacaaaa aggtccaata gtaggtcaga tggctatgac tctctagaac
    20101 ccgataagag gtttcatctg catgaagaag agcttgttct aacaactttt ctcgtaaaag
    20161 attataaagg ggctccaaat aatagtgact cgtcttgata tgccaattag aaatttcctt
    20221 acgtgtgatt ggtaaaccca tcttagccca atcttcttct tagtgataat tgggtacctt
    20281 cagaataaac ttctgatgga tggtgtgagc gataatagaa gctgagccaa ggctatgcgc
    20341 caaaggggct ttaggaatag gagctttcac gattttatca ctccgatttt tatcactgca
    20401 tgcttggcac ttataagcgt gttggatatg atctattcgt tttaattgcg caggaataaa
    20461 gactaattct tgtcgttgaa gggttgctcc aatctctttt agatcatcct gacaatcagg
    20521 gcaaatgctc tcttctactt gatgatgaac tttttctgaa tcaaattggg caagaagagc
    20581 ttggcgtttc cctttagatt tcttacgttt gtaggtaatt tcctctgttt caactgggaa
    20641 catctccatc tttctcagat ggagactctt cctcaaaaag gttgagttgt ccagaagggc
    20701 aaacactttt ctcagaggat tttccataga gcttttgcgt tagataagcc acttgttcac
    20761 gcagaaggga aagttcatta gtgagactat caattatagc actctgttgt tgaatgattt
    20821 tcaatcttct tccatgagct tccctctcta ttttctaact ttattatact aaaaagaaag
    20881 tcctcatttc aatagaaatc acgactttct gatgaattta tagtaaaatg aaataataac
    20941 aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gcagaggtgt
    21001 actattctag tttcaattta ctatattttt ggagtgatag aaaagccctt cataagccag
    21061 tctacttgtt ctggtgtgag agctttgaca tccttttctg tactgggcca agtcagtctg
    21121 ccgttctcaa agcgtttata tagtagccaa aatccttgac catcccagta aagggcttta
    21181 aagcggtctt tacgtccacc acaaaagaga aaaacttgac ctgagaaagg atctaattca
    21241 aagtgggttt taaccagata agccagtgaa tcaatgcctt gcctcatatc cgttttccca
    21301 cacacgagat agacctgccc taggctaaat agatgaattg tcatagagca acaccttatc
    21361 caaaagctgt tctatcattt cgagattgag agattgaaaa aaacttactt caagcttgcc
    21421 aatacgaatt ttaagcagaa tatcatttct ctttttagaa tcaaaacgac gagattgtgg
    21481 aatctctaca ggaacaatag gttgtggcat taaaatatcc tccaatagtt ttactttact
    21541 aatagtatac aggaggagct ccatgaatga tagatacctt gttatgacgc gcttacgata
    21601 tagttgaggg atttttaaat gatattcata ttttttgcaa agatgttgtt tgaaaaataa
    21661 ttttcaaaaa ttctgaaaat tctgttgaca actttctgaa aagagtctat aatggagaga
    21721 aagttttaaa ggagaaaatg atgaaaagtt caaaactatt tgcccttgcg ggcgtgacat
    21781 tattggcggc gactacttta gctgcatgct ctggatcagg ttcaagcact aaaggtgaga
    21841 agacattctc atacatttat gagacagacc ctgataacct caactatttg acaactgcta
    21901 aggctgcgac agcaaatatt accagtaacg tggttgatgg tttgctagaa aatgatcgct
    21961 acgggaactt tgtgccgtct atggctgagg attggtctgt atccaaggat ggattgactt
    22021 acacttatac tatccgtaag gatgcaaaat ggtatacttc tgaaggtgaa gaatacgcgg
    22081 cagtcaaagc tcaagac
//
