LOCUS       CR931717               24095 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain Hammer (serotype 44).
ACCESSION   CR931717
VERSION     CR931717.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24095)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 24095)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..24095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Hammer"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC44_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC44_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34743.1"
                     /db_xref="GOA:Q4K2R1"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K2R1"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVP
                     WDAFCVELL"
     gene            322..490
                     /gene="aliB"
                     /locus_tag="SPC44_0002"
                     /pseudo
     CDS             322..490
                     /gene="aliB"
                     /locus_tag="SPC44_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(488..1009)
                     /gene="tnp"
                     /locus_tag="SPC44_0003"
                     /pseudo
     CDS             complement(488..1009)
                     /gene="tnp"
                     /locus_tag="SPC44_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            1222..2676
                     /gene="wzg"
                     /locus_tag="SPC44_0004"
     CDS             1222..2676
                     /gene="wzg"
                     /locus_tag="SPC44_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34746.1"
                     /db_xref="GOA:Q4JYS2"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JYS2"
                     /translation="MLIMSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNI
                     LAFRYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGL
                     TNRLNATSNYSEYSISVVVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNT
                     DLTVNQSSSYLAAYKSLIAGETKAIVLNSVFENIIELEYPDYASKIKKIYTKGFTKKV
                     EAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPI
                     ADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVH
                     NDQEFSALHGKFYFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKL
                     TSTEALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDL
                     PSYAMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1222..1347
                     /gene="wzg"
                     /locus_tag="SPC44_0004"
                     /note="Signal peptide predicted for SPC1935 by SignalP 2.0
                     HMM (Signal peptide probability 0.991) with cleavage site
                     probability 0.537 between residues 42 and 43"
     misc_feature    1435..1782
                     /gene="wzg"
                     /locus_tag="SPC44_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 1.8e-63"
     misc_feature    1960..2403
                     /gene="wzg"
                     /locus_tag="SPC44_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 1.5e-69"
     gene            2678..3409
                     /gene="wzh"
                     /locus_tag="SPC44_0005"
     CDS             2678..3409
                     /gene="wzh"
                     /locus_tag="SPC44_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34747.1"
                     /db_xref="GOA:Q4JYS1"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JYS1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    2681..3289
                     /gene="wzh"
                     /locus_tag="SPC44_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 1.3e-36"
     gene            3415..4110
                     /gene="wzd"
                     /locus_tag="SPC44_0006"
     CDS             3415..4110
                     /gene="wzd"
                     /locus_tag="SPC44_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34748.1"
                     /db_xref="GOA:Q4K1W4"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K1W4"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSAFI
                     VKPEYTSTTRIYVVNRDQGDKSGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKL
                     DIPAKTLARKVQVTVPVDTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDV
                     TTLEEARPATTPSSPNVGRNSLFGFFGGAVVTVIAVLLIELFDIRVKRPEDVEDVLQI
                     PLLGVVPDLDKMK"
     misc_feature    3415..3531
                     /gene="wzd"
                     /locus_tag="SPC44_0006"
                     /note="Signal peptide predicted for SPC1937 by SignalP 2.0
                     HMM (Signal peptide probability 0.729) with cleavage site
                     probability 0.460 between residues 39 and 40"
     misc_feature    3436..3852
                     /gene="wzd"
                     /locus_tag="SPC44_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1.4e-54"
     misc_feature    3958..4035
                     /gene="wzd"
                     /locus_tag="SPC44_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4120..4794
                     /gene="wze"
                     /locus_tag="SPC44_0007"
     CDS             4120..4794
                     /gene="wze"
                     /locus_tag="SPC44_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34749.1"
                     /db_xref="GOA:Q4JYR9"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JYR9"
                     /translation="MPTLEISQAKLDFVKKAEENYNALCTNLQLSGDDLKVFSITSVK
                     QGEGKSTTSINIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITQKCDASILVTKAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGKK"
     gene            5141..5740
                     /gene="wciI"
                     /locus_tag="SPC44_0008"
     CDS             5141..5740
                     /gene="wciI"
                     /locus_tag="SPC44_0008"
                     /note="member of homology group 29"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34750.1"
                     /db_xref="GOA:Q4JYR8"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q4JYR8"
                     /translation="MYRVTKRLGDILLSLIGIIVLFPVFIVIAIAINTDSEGPIIFKQ
                     KRFRIYKEPFYILKFRSMKIGAPKNVAPRNLDNPEQWITKVGAFLRKTSLDELPQLWN
                     ILIGNMSIVGPRPAGINELDLLTEREKFGANDVLPGLTGWAQINGRDTLSIEMKAEAD
                     GYYVKHMSLSMDLRCIIRTIPYVLKRKGIVEGSGKKELD"
     misc_feature    5141..5233
                     /gene="wciI"
                     /locus_tag="SPC44_0008"
                     /note="Signal peptide predicted for SPC1939 by SignalP 2.0
                     HMM (Signal peptide probability 0.994) with cleavage site
                     probability 0.844 between residues 31 and 32"
     misc_feature    5156..5710
                     /gene="wciI"
                     /locus_tag="SPC44_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 4.6e-30"
     gene            5706..6971
                     /gene="wciJ"
                     /locus_tag="SPC44_0009"
     CDS             5706..6971
                     /gene="wciJ"
                     /locus_tag="SPC44_0009"
                     /note="member of homology group 35"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34751.1"
                     /db_xref="GOA:Q4JYR7"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYR7"
                     /translation="MWRAVVRKSWIDAMKILFVCQHYKPEPFRLSDICEDLVQRGHEV
                     AVLTGIPNYPEGEIYADYRKRKKRRETINGVAIFRSYTIARRQNTLYRILNYFSFALS
                     STIGVIFGRYKAKDGSDFDCVFVNQLSPVMMAWAGIAYKNKYNKPMFLYCMDVWPDSL
                     IVGGVKENGLIYKIFEFVSKKVYQASDYIFVTSLSFKDYFVKKFNIPLHKITYLPQYA
                     EDLFVPNELKTNKNTIDLTFAGNIGKAQNLETILKAASAIEQIPDLAKRVHFHFVGDG
                     TELLNMQKLACELELENTSFYGRRPLEEMPDFYTKSDAMLVSLIGDSIISRTLPGKVQ
                     SYMAAGKPIIGAISGDTQRVVKEAKCGFISPEGNVDQLVRNIRKFCLLSVEEREKLGR
                     QARCYYEEQFSKEWFMTYLENHLKEGFLS"
     misc_feature    6363..6896
                     /gene="wciJ"
                     /locus_tag="SPC44_0009"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 3.8e-16"
     gene            6920..8137
                     /gene="wcxB"
                     /locus_tag="SPC44_0010"
     CDS             6920..8137
                     /gene="wcxB"
                     /locus_tag="SPC44_0010"
                     /note="member of homology group 55"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34752.1"
                     /db_xref="GOA:Q4JYR6"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYR6"
                     /translation="MVYDILRKSFKRGVSIMKVLMINSVCGIRSTGRICADLATALTE
                     EGYEVKIAYGREYVPKQFQQYAVKIGTKSDIRFHAIRSRLFDESGFGSRQATVNFIKW
                     MKEFDPDIIHLHNLHGYYINVELLFDYLRICGKKIIWTLHDCWAFTGHSAYFDCLECE
                     SKGVCDHPSQKNDYPKSFVNFSKRNYQRKKKCFTHIPNLTIVTPSQWLANLVRQSFLK
                     EYPVKVIHNGIDTTVFQPRLIAAQKLRKRHHLEGKQVLLGVAAIWDNRKGFSDMLALA
                     NDLTDNQRIVLIGLKDRQLKELPKGIIGLTETNSPEELVAWYTLADVFLNPTYQDNYP
                     TTNLEAISCGTPVISYPTGGSVESAKLYGLVCQDRNVASILSSLEKVSQLSKTEKLDF
                     SIASFIKQMKYLY"
     misc_feature    7640..8122
                     /gene="wcxB"
                     /locus_tag="SPC44_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 4.2e-12"
     gene            8175..9386
                     /gene="wzy"
                     /locus_tag="SPC44_0011"
     CDS             8175..9386
                     /gene="wzy"
                     /locus_tag="SPC44_0011"
                     /note="member of homology group 71"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34753.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q4K1V9"
                     /translation="MMKRIYYHLLAIWAWTLPNSYAFIDSLKVFFPNISLQIAGSLLA
                     VVSIGIFITRIYYTRYEVFISLLVCISILIFYSTRFFYSTNVELYQSFFNSFLIRPVP
                     AILVAMLLAKNNHIKGFIKWSEPMMLFYTLTSFLAALSPRNSIITYQSLSYYAMTAYM
                     INVFNIIYKEKILEEQLTYFRFSAWNFIRYFLLLIQAFNALSGGGRGAFILLIIFTGI
                     LLIRTAMKFKFLFSFIGGLSAIALVVFFTKGLDLTWLLNMDGGERLLNFFGRPEHIST
                     DNRLLIYDTVWSAIQEKPFLGWGVGSTFLKFNGYSHNIVLDLLHDMGSFGLLIILSAF
                     FASSVILYKLRKIDWKVNLFILMFLEVYVHMSFSGSYLADGRLWFLVIFTYCYYRWKV
                     QEKDEVSNFII"
     misc_feature    8991..9158
                     /gene="wzy"
                     /locus_tag="SPC44_0011"
                     /note="HMMPfam hit to PF04932, O-Antigen Polymerase, score
                     9.9e-08"
     gene            9361..10437
                     /gene="wcxD"
                     /locus_tag="SPC44_0012"
     CDS             9361..10437
                     /gene="wcxD"
                     /locus_tag="SPC44_0012"
                     /note="member of homology group 72"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34754.1"
                     /db_xref="GOA:Q4K1V8"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K1V8"
                     /translation="MKLAILLSDISKIGGVQRVTTALVNELCQNIDVTIISIFSENEL
                     PAFGLSDRVQVSYLLKEHVNLKKNFFKVSGALRKVLKKQQFDVVLSSGTGLVSFLWFA
                     SLGIPTRLLAWEHQCFYFGRSFGLEWLGRKLACRFAESIVVLTKKDEGFYKENRPKAH
                     IEQIYNILDMDSQTAKCQLSSKKIISVGSLVRQKGFDLALEVASQIQLSYPDWQWDIY
                     GDGPDREKLEEKVREYQLEGFINLKGLVQNVRELYPDYSIYALTSRYEGLSMVLLEAK
                     NCQMPAISFDCNCGPSDIISDGRNGFLIDCFDVNIYAKTLSKLMTSLELREQVAKSSV
                     IPAEELSTTYILDKWNNLLKIERR"
     misc_feature    9862..10368
                     /gene="wcxD"
                     /locus_tag="SPC44_0012"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.2e-33"
     gene            10439..11617
                     /gene="wcxE"
                     /locus_tag="SPC44_0013"
     CDS             10439..11617
                     /gene="wcxE"
                     /locus_tag="SPC44_0013"
                     /note="member of homology group 73"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34755.1"
                     /db_xref="GOA:Q4K1X6"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4K1X6"
                     /translation="MKIVHVEDFFHPDAGYQINVLPKYLAKFGHEQVIITSEMDKIPD
                     NLTQFFGRENIEERDRSYEEKHHVKIIRLPLHGFVSGRAIFSGKLISAIKGLSPEVLY
                     IHGNDTLTGIRLLLARKKLNCRIVTDSHMLEMASRNPFNNYFRRFYKTLITPILIKEQ
                     IPIIRTQDDNYVEKHLGIPLSQAPWISYGSDTAFFHADSQIKEDFRSQYQIASDALIC
                     VYAGKLDEHKGGMFLAESLSKKLNTEQPIVFIIVGNTNGEYGEAVEKSFSQSENQILR
                     FPTQKYQKLAQFFQVADFALFPKQCSLSFYDAQACGLPVLLEDNNINLDRTSHYNGWT
                     FKANSKLSLRDSLKMIASLDKEKRQEYSQNALHYILEHYNYEDKAREYEKILIGERTK
                     "
     misc_feature    11042..11542
                     /gene="wcxE"
                     /locus_tag="SPC44_0013"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 0.00013"
     gene            11650..12846
                     /gene="wcxF"
                     /locus_tag="SPC44_0014"
     CDS             11650..12846
                     /gene="wcxF"
                     /locus_tag="SPC44_0014"
                     /note="member of homology group 74"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34756.1"
                     /db_xref="GOA:Q4JYR2"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYR2"
                     /translation="MDLMKICIVSVGVGGLPIPAVKGGAVENLIDNYLSYNEKYNHDE
                     ITVVSCDHKEAREASKKYKYAQFVYIDIHSLKYKINKTIRYAINKYSPFFVGNAYISQ
                     LPDLSGFDTVLIENRPEYGYYIRKKFKGNLVLHLHNDLLMDNEYSVDYSVYDKIITVS
                     DYIRNRSEVVTSGVPIQTVYNGIDTEPFLQNFSEVDLSDLKNQLEILSDDFVIVFFGR
                     INKNKGIKELLEAFLLLPKNLNIKLLAVGSSIFGQTELDTFTTEIRQLAKQASDKVVF
                     TGYVNYKDIPKYHHIADCIVVPSIWEEPAALTVCEALISGKYVITTDTGGTPELVAGS
                     DALVVANDECIVEHLKTALLSVYQKGKCSSVITSNRDRGTYFSIEKYGRNLRKELTQN
                     ERIINI"
     misc_feature    11650..11724
                     /gene="wcxF"
                     /locus_tag="SPC44_0014"
                     /note="Signal peptide predicted for SPC1945 by SignalP 2.0
                     HMM (Signal peptide probability 0.653) with cleavage site
                     probability 0.406 between residues 25 and 26"
     misc_feature    12238..12765
                     /gene="wcxF"
                     /locus_tag="SPC44_0014"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 2.6e-25"
     gene            12843..14387
                     /gene="wzx"
                     /locus_tag="SPC44_0015"
     CDS             12843..14387
                     /gene="wzx"
                     /locus_tag="SPC44_0015"
                     /note="member of homology group 56"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34757.1"
                     /db_xref="GOA:Q4JYR1"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JYR1"
                     /translation="MSRVKNSFFNILAGIVGTIISSVLAFIVRTVFIRVLGETYLGFN
                     GLYTNILTVLSLTELGIGSSIAYLMYKPLAEKDGDKLAQVVQFYKKIYRVIGIIILIL
                     GLCLVPFLPVIVNLKNAEDLNYTALYLLYLADTVSTYLFFAYKRGVLAADQKIYVANI
                     FDIIITTILSIFQIITLMIFKDFYLYIILKIAKNLTLNLVISLKVDKMYPSIHKFKGI
                     APLPKMERRLVWKNVYATSVRQIFNELMNSTDSIVISIVLGIVMVGKYSNYAYILSIV
                     YIFFGGIFNPIQASIGNLSLLASIEKKNEIFNRLRFINFFFLSFCSSCLLVLVNPFIT
                     IWIGENYTLSFTGVIAIVGMLFVRQTGNCTTIFRLGEGYFRDYHFSPLIAGILNLVVS
                     VILVNYIGIAGVFVGTMLGFGFQFILVDTIVTYKKVLSRPLSEFYLRWLQTILLTVGL
                     CIASYYLSRLVRVNSIYDLILLFVVVIGFNFFALCFIYWRNDDFQYFIQLVKNFMKNL
                     EEKNHD"
     misc_feature    12843..12917
                     /gene="wzx"
                     /locus_tag="SPC44_0015"
                     /note="Signal peptide predicted for SPC1946 by SignalP 2.0
                     HMM (Signal peptide probability 0.819) with cleavage site
                     probability 0.398 between residues 25 and 26"
     gene            14380..15603
                     /gene="mnaB"
                     /locus_tag="SPC44_0016"
     CDS             14380..15603
                     /gene="mnaB"
                     /locus_tag="SPC44_0016"
                     /note="member of homology group 75"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmannosamine dehydrogenase MnaB"
                     /protein_id="CAI34758.1"
                     /db_xref="GOA:Q4K1X3"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4K1X3"
                     /translation="MINVIGLGYIGLPTILMLATNGVKVVGTDYNQDLVRTLNEGQTT
                     FKEDGLDELFHKAVESGVDFTTEYQQTDTYIISVPTPYDSFSKKIDPSYVIEATKTVL
                     DNCNKGAVIIIESTVSPGTVDKFIRPVVEEKGFVIGSDIHLVHAPERIIPGNMVYELV
                     NNNRTIGADDLEIGYKVKELYASFCKGDIVVTDIRTAEMTKVVENTFRAVNIAFANEL
                     AQICSYDNMNVYEIIRICNMHPRVNILQPGPGVGGHCISVDPWFLVGDYPELTNVIEH
                     SMRTNAAMPEFVLNRIYTIMNEHHLTDISRVGLYGLTYKENVDDMRESPTLQLLESMS
                     RHLATPAIKVYDPFIEKDVVANQSHDLDEFLSNVDIVVLLVGHDEILQNMDKLKDKIV
                     LDTRYICHLDGTYRL"
     misc_feature    14383..14937
                     /gene="mnaB"
                     /locus_tag="SPC44_0016"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.4e-45"
     misc_feature    14959..15219
                     /gene="mnaB"
                     /locus_tag="SPC44_0016"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 4.5e-33"
     misc_feature    15301..15564
                     /gene="mnaB"
                     /locus_tag="SPC44_0016"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 2.5e-15"
     gene            15626..16729
                     /gene="mnaA"
                     /locus_tag="SPC44_0017"
     CDS             15626..16729
                     /gene="mnaA"
                     /locus_tag="SPC44_0017"
                     /EC_number="5.1.3.14"
                     /note="member of homology group 23"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine-2-epimerase MnaA"
                     /protein_id="CAI34759.1"
                     /db_xref="GOA:Q4K1V3"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q4K1V3"
                     /translation="MTMKKIVVIFGTRPEAIKMCPLVKELRTRENLETLVCVTGQHRQ
                     MLDQVLDTFRITPDFDLSIMKDKQTLFDVTIGILEGMKTVLESVNPDLILVHGDTSTT
                     FASSLAAFYLQIPIGHVEAGLRTYDIYSPYPEEFNRQAVGALAQYHFTPTQLSKDNLL
                     REGKNSEAIFITGNTAIDALQTTIQEDYTHPELNWVGDSKLILITAHRRENIGDPMRH
                     MFRAIRRIIEEHSDIKALYPIHMNPLVRQIAEEELSGCERIKMIDPLEVLDFHNFLSR
                     SYLILTDSGGIQEEAPSLGKPVLVMRDTTERPEGIKAGTLKLVGTDEDNIYRHFKELL
                     ENDLVYQAMSQASNPYGDGTACKKIADILEGEV"
     misc_feature    15695..16717
                     /gene="mnaA"
                     /locus_tag="SPC44_0017"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 2.5e-174"
     gene            order(16733..17173,17175..17786)
                     /gene="fnlA"
                     /locus_tag="SPC44_0018"
     CDS             join(16733..17173,17175..17786)
                     /gene="fnlA"
                     /locus_tag="SPC44_0018"
                     /note="member of homology group 36"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlA"
                     /protein_id="CAI34760.1"
                     /db_xref="GOA:Q4JYQ8"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR013692"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYQ8"
                     /translation="MSQFTGKTLLITGGTGSFGNAVLNRFLQTDIGEIRIFSRDEKKQ
                     DDMRHEFQVKVPEVAGKIRFYLGDVRDLASVKNAMHGVDYVFHAAALKQVPSCEFFPV
                     EAVKTNILGTENVLTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAMEKIAVAKSRTVN
                     PEHTKICVTRYGNVLCSRGSVVPLWIEQIKQGNALTITEPSMTRFVMTLEEAVDLVLF
                     AFEEGKSGDILVQKAPACTIEVLAKAVSEIFASEQDIKIIGIRHGEKRYETLLTNEEC
                     ANAIDLGDFYRVPSDNRNLNYDKYFKDGSTNRNLLTEFNSNNTDLMDVEQVKRKLLEL
                     DEIQTAIRDMVADEEM"
     misc_feature    order(16754..17173,17175..17606)
                     /gene="fnlA"
                     /locus_tag="SPC44_0018"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.0046"
     misc_feature    order(16757..17173,17175..17426)
                     /gene="fnlA"
                     /locus_tag="SPC44_0018"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 3.1e-08"
     misc_feature    order(16757..17173,17175..17603)
                     /gene="fnlA"
                     /locus_tag="SPC44_0018"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 2.7e-158"
     misc_feature    order(16760..17173,17175..17393)
                     /gene="fnlA"
                     /locus_tag="SPC44_0018"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2e-08"
     misc_feature    17604..17747
                     /gene="fnlA"
                     /locus_tag="SPC44_0018"
                     /note="HMMPfam hit to PF08485, Polysaccharide biosynthesis
                     protein C, score 2e-23"
     gene            17886..19115
                     /gene="fnlB"
                     /locus_tag="SPC44_0019"
     CDS             17886..19115
                     /gene="fnlB"
                     /locus_tag="SPC44_0019"
                     /note="member of homology group 37"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlB"
                     /protein_id="CAI34761.1"
                     /db_xref="GOA:Q4K1V1"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K1V1"
                     /translation="MIKNILITGAKGFVGKNLICTLEALKDGRDRTRPNLEIGEIFQY
                     DRDTDPILLDEYCKKADFVFHLAGVNRPQNPDEFMEGNYGFSSRLLEILEKYENTCPV
                     LLSSSTQASLEGRFSNSIYGQSKLAGEELFFEYGKKTGAPVLVYRFPNLYGKWCRPNY
                     NSAVATFCHNLAHDLPIQVNDPSVELELLYIDDLIQECLTALEGNPHRCNLDGLQILP
                     SPSGNYCYVPTTHRATLGEIVSLLETFKKQPNSLVMPEIPQGSFKKKLYSTYLSYLPV
                     DKFRFPLKMNIDERGSFTELLKTENTGQFSVNISKPGITKGQHWHHSKWEFFMVVSGR
                     ALIQERRIGLDENGQEYPILNFEVSGDKIEAIHMIPGYAHNIINLSDTENLITVMWAN
                     ESFDPRHPDTFFEQVEK"
     misc_feature    17898..18521
                     /gene="fnlB"
                     /locus_tag="SPC44_0019"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 6.9e-09"
     gene            19116..20300
                     /gene="fnlC"
                     /locus_tag="SPC44_0020"
     CDS             19116..20300
                     /gene="fnlC"
                     /locus_tag="SPC44_0020"
                     /note="member of homology group 38"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-L-fucosamine FnlC"
                     /protein_id="CAI34762.1"
                     /db_xref="GOA:Q4JYQ6"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q4JYQ6"
                     /translation="MKIKTDYSDIHFKDNGKLKLLIIVGTRPEIIRLSSVITKCRKYF
                     DVILAHTGQNYDYNLNGIFFDNLGLDTPDVYMDAVGDDLGATVGNIINTSYKLMNQIK
                     PDALLILGDTNSCLSAIAAKRLHIPIFHMEAGNRCKDECLPEETNRRIVDIISDVNLA
                     YSEHARKYLHECGLPKERTYVTGSPMAEVLHKNLPAIESSDIHERLGLKKGGYILLSA
                     HREENIDTDKNFISLFTAINQLAEKYNMPILYSCHPRSKKRLQESGFKLDKRVIQHEP
                     LGFHDYNCLQMNAFVVVSDSGTLPEESSFFTSQGYPFPAVCIRTSTERPESLDKAGFI
                     LAGIDENSLLQAVETAVSLAEDEDFGLPVPDYVEENVSTKVVKIIQSYTGIVDKIVWR
                     KS"
     misc_feature    19227..20255
                     /gene="fnlC"
                     /locus_tag="SPC44_0020"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 9.7e-106"
     gene            complement(20498..20584)
                     /gene="tnp"
                     /locus_tag="SPC44_0021"
                     /pseudo
     CDS             complement(20498..20584)
                     /gene="tnp"
                     /locus_tag="SPC44_0021"
                     /note="Lone member of homology group 0256"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase (fragment)"
     gene            complement(20663..21608)
                     /gene="tnp"
                     /locus_tag="SPC44_0022"
                     /pseudo
     CDS             complement(join(20663..20884,20895..21608))
                     /gene="tnp"
                     /locus_tag="SPC44_0022"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase (fragment)"
     gene            21711..21899
                     /gene="tnp"
                     /locus_tag="SPC44_0023"
                     /pseudo
     CDS             21711..21899
                     /gene="tnp"
                     /locus_tag="SPC44_0023"
                     /note="member of homology group 0047 7"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            complement(21982..22684)
                     /gene="tnp"
                     /locus_tag="SPC44_0024"
                     /pseudo
     CDS             complement(join(21982..22434,22415..22684))
                     /gene="tnp"
                     /locus_tag="SPC44_0024"
                     /note="member of homology group 31"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase"
     misc_feature    complement(order(22415..22419,22099..22434))
                     /gene="tnp"
                     /locus_tag="SPC44_0024"
                     /note="HMMPfam hit to PF05717, IS66 Orf2 like protein,
                     score 8.3e-52"
                     /pseudo
     gene            order(22751..23060,23086..23475)
                     /gene="tnp"
                     /locus_tag="SPC44_0025"
                     /pseudo
     CDS             join(22751..22948,22947..23060,23086..23475)
                     /gene="tnp"
                     /locus_tag="SPC44_0025"
                     /note="member of homology group 19"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
     misc_feature    order(22998..23060,23086..23463)
                     /gene="tnp"
                     /locus_tag="SPC44_0025"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 2.7e-15"
                     /pseudo
     gene            23736..>24095
                     /gene="aliA"
                     /locus_tag="SPC44_0026"
     CDS             23736..>24095
                     /gene="aliA"
                     /locus_tag="SPC44_0026"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34768.1"
                     /db_xref="GOA:Q4K2T2"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K2T2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    23736..23822
                     /gene="aliA"
                     /locus_tag="SPC44_0026"
                     /note="Signal peptide predicted for SPC1961 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    23982..24050
                     /gene="aliA"
                     /locus_tag="SPC44_0026"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     7730 a   3781 c   4860 g   7724 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
      121 aatcttagtt ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcgtat aaaaacaagg gaggactgta taaaaggcag aaatcctttg
      241 ttttttataa ccaaggttta taaaccttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gacgaacata aagaagcgta tccttagtgc aggcctgact
      361 tttacatctg ctttgctttt agctacttgc ggccaatcag gttcagatat aaaaacttac
      421 tcatcaacct ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat
      481 aatatagtca attgaaacaa gaacaagaca aaagagcctc ataaaaggta ttgcaacttg
      541 gtaatacctt tttgaggtgc tttttgatat gagcccatgt tttctcaata ggattgtact
      601 caggtgagta gggaggaaga ggtaaaagtt tatgcccaaa ctcttcgcat aaaagttcta
      661 gcttccccat tctatggaat cttgcattat ccataataat aaccgatggt gtgtttaatg
      721 ttggtaagaa aaacttctga aaccatactt caaaaaagtc gctcgtcatc gtctcttcgt
      781 aagtcattgg aacgattaat tcaccatttg ttagacctgc aaccaaagaa attctctgat
      841 atcttcttcc agatactttg cctcttctta actgaccttt taatgagcga ccatattctc
      901 gataaaaata agtatcgaat cctgtttcgt caatctaaac aggtgctagg tgctttaaac
      961 tattaaaatt cttaagaaat aaggctactt tttctgggtc ttgttcataa ttagattgaa
     1021 actagagtag tacacctctg cttctaaaaa atttttagaa atcgatttaa ctgtcctgat
     1081 cgatttgtca tgttcttatt tcattttatt atatttttgg ttcgcgggaa gtctactaag
     1141 atacttaaag atgcagatag taaaaaaaat gtagacatta ccgtaaaaaa gtgatataat
     1201 cgtatgatgt tcaaggtata ggtgttaatc atgagtagac gttttaaaaa atcaggttca
     1261 cagaaagtga agcgaagtgt taatatcgtt ttgctgacta tttatttatt gttagtttgt
     1321 tttttattgt tcttaatctt taagtacaat atccttgctt ttagatatct taacctagtg
     1381 gtaactgcgt tagtcctact agttgccttg gtagggctac tcttgattat ctataaaaaa
     1441 gctgaaaagt ttactatttt tctgttgctg ttctctatcc ttgtcagctc tgtgtcgctc
     1501 tttgcagtac agcagtttgt tggactgacc aatcgtttaa atgcgacttc taattactca
     1561 gaatattcaa tcagtgtcgt tgttttagca gatagtgata tcgaaaatgt tacgcaactg
     1621 acgagtgtga cagcaccgac tgggactgat aatgaaaata ttcaaaaact actagctgat
     1681 attaagtcaa gtcagaatac cgatttgacg gtcaaccaga gttcgtctta cttggcagct
     1741 tacaagagtt tgattgcagg ggagactaag gccattgtcc taaatagtgt ctttgaaaac
     1801 atcatcgagt tagagtatcc agactacgca tcgaagataa aaaagattta taccaaggga
     1861 ttcactaaaa aagtagaagc tcctaagacg tctaagaatc agtctttcaa tatctatgtt
     1921 agtggaattg acacctatgg tcctattagt tcggtgtcgc gatcagatgt caatatcctg
     1981 atgactgtca atcgagatac caagaaaatc ctcttgacca caacgccacg tgatgcctat
     2041 gtaccaatcg cagatggtgg aaataatcaa aaagataaat taacccatgc aggcatttat
     2101 ggagttgatt cgtccattca caccttagaa aatctctatg gagtggatat caattactat
     2161 gtgcgattga acttcacttc tttcttgaaa atgattgact tattgggagg ggtagatgtt
     2221 cataatgatc aagagttttc agctctacat gggaagttct atttcccagt agggaatgtc
     2281 catctagact ctgagcaggc tctaggtttt gtacgtgaac gctactcact agccgatgga
     2341 gaccgtgacc gtggtcgcaa ccaacaaaag gtgattgtgg ctatccttca aaaattaacg
     2401 tcaaccgaag cactgaaaaa ttatagtacg atcattaata gcttgcaaga ttctatccaa
     2461 acaaatatgc cacttgagac tatgataaat ttggtcaatg ctcagttaga aagtggaggg
     2521 aattataaag taaattctca agatttaaaa gggacaggtc ggacggatct tccttcttat
     2581 gcaatgccag acagtaacct ctatgtgttg gaaatagatg atagtagttt agctgtagtt
     2641 aaagcagcta tacaggatgt gatggagggt agatgaaatg atagacatcc attcgcatat
     2701 cgtttttgat gtagatgacg gtcccaagtc aagagaggaa agcaaggctc tcttggcaga
     2761 atcctacagg caaggggtac gaatcattgt ctctacctct caccgtcgca agggcatgtt
     2821 tgaaactccg gaagagaaga tagcagaaaa ctttcttcag gttcgggaaa tagctaagga
     2881 agtggcgagt gacttagtca tcgcttacgg ggctgaaatt tactacacac cagatgttct
     2941 ggataagcta gaaaaaaagc ggattccgac cctcaatgat agtcgttatg ccttgataga
     3001 gtttagtatg aacactcctt atcgcgatat tcatagcgcc ttgagcaaga tcttgatgtt
     3061 gggaattact ccagtcattg cccacattga gcgctatgat gctcttgaaa ataatgaaaa
     3121 acgcgttcga gaattgatcg atatgggctg ttacacgcaa gtaaatagtt cacatgtcct
     3181 caaatccaaa ctttttggcg aacgttataa attcatgaaa aaaagagctc agtatttttt
     3241 agagcaggat ttggtccatg tcattgcaag tgatatgcac aatctagacg gcagacctcc
     3301 tcatatggca gaagcatatg accttgttac ccaaaaatac ggagaagcga aggctcagga
     3361 actttttata gacaatcctc gaaaaattgt aatggatcaa ctaatttagg agaaatgatg
     3421 aaagaacaaa acacgataga aatcgatgta tttcaattat ttaaaacctt gtggaaacgc
     3481 aagctaatga ttttattagt ggcacttgtg acaggtgcgg gggcttttgc atatagcgct
     3541 tttattgtta agccagaata tacgagtacc acgcgaattt acgtagtgaa tcgcgatcaa
     3601 ggagacaagt cggggctgac aaatcaggat ttgcaggcag gatcttatct ggtaaaagac
     3661 taccgtgaga ttatcctttc gcagaatgta ttggaaaaag tagcgacaaa tttgaagttg
     3721 gatataccag ccaaaacgtt agctagaaaa gttcaagtga ctgtaccagt tgacactcgt
     3781 atcgtctcaa tctctgtcaa ggataaacag ccagaggaag ccagtcgtat cgctaattct
     3841 ctacgagaag ttgctgcaga aaagatcatc gctgtaacgc gagtatctga tgtgacgaca
     3901 cttgaagaag cgcgaccagc tacgactccc tcttctccaa atgttggacg caattccttg
     3961 tttggttttt ttggaggagc agtcgtaaca gtaattgctg ttcttttgat tgagttgttc
     4021 gacatccgtg tgaaacgtcc tgaagatgtc gaagatgtac tgcaaattcc acttttaggg
     4081 gtcgttccag atttggacaa aatgaaatag gaggaagtta tgccaacatt agaaatctca
     4141 caggcaaaat tggattttgt aaaaaaggca gaggaaaatt ataacgcttt gtgcacgaac
     4201 ctacagttaa gtggagatga tttgaaagta ttttctatca cttctgtgaa acaaggagaa
     4261 ggaaaatcaa cgacttccat caatatcgct tgggcttttg cgcgtgcagg ttacaaaacg
     4321 ctgctgattg atggagatat tcgcaattct gttatgttag gtgtctttaa agcaagagat
     4381 aagattacag gcctgacaga atttttatca ggaactacag acctatcaca agggctttgt
     4441 gataccaata tcgaaaatct ctttgtaatt caggctggct ctgtgtcacc gaatccgaca
     4501 gctcttcttc aaagtaagaa tttcagtaca atgcttgaaa ccttgcgtaa atattttgac
     4561 tacatcattg tagatactgc tcctgtcggt gtcgtgattg atgcggctat tattacgcaa
     4621 aaatgcgatg cttctatttt agtgacgaag gcaggtgaaa taaatcgacg ggatattcaa
     4681 aaagcaaaag aacagttgga acacacaggg aagccgtttt tgggagttgt gttgaataaa
     4741 ttcgatactt cagtagacaa atacggttct tatggaaatt acggaaaaaa ataagtcgtt
     4801 aagtatttgt gtaaggacat ttttagaact acaatcaaaa tctttggaat tgctggcttc
     4861 aaatcatatt gatttgaaat gaaacttgca aaagagtttt taaggtgagt ttcttaattt
     4921 gtgactgaaa tcaatcttct acttccatac cttggaaaaa cagggtaaac gagagatgtt
     4981 ttttccataa taaagttttg atatggctag tagagtagta atataatgaa ttgtaatcat
     5041 tagtgttcat accaagaaat atcaagtatc tatttttgaa aatcataaat atgagatagt
     5101 ttttaaatct ctaaggagag ctagttttga gaggtaattt atgtatagag taacaaaacg
     5161 attaggggat attttacttt ctttaatagg aataatagta ctgtttccag tgtttattgt
     5221 aattgcaatt gcgataaaca ctgattcgga gggtccgatt atatttaaac aaaaacgatt
     5281 taggatatac aaggaacctt tttatatcct gaaatttagg tccatgaaaa taggagcacc
     5341 gaaaaatgta gctccacgga acttggataa tccagaacag tggattacca aagtgggagc
     5401 tttcttaaga aaaacatctt tggacgaact gccacaatta tggaatattc ttattggtaa
     5461 tatgagcatt gtaggaccta ggccagcagg tataaatgag cttgatttgc tcaccgaaag
     5521 agaaaagttt ggtgcgaatg atgtcttacc tggattaact ggatgggcac aaattaatgg
     5581 gcgagatact ttgtcaatag agatgaaggc agaagcagat ggttattatg tgaaacatat
     5641 gtcgttaagc atggatctta gatgtatcat taggacaatc ccctacgtat taaaacgtaa
     5701 gggaattgtg gagggcagtg gtaagaaaga gttggattga tgcaatgaaa attctatttg
     5761 tttgtcaaca ttataagcca gaacctttta ggttgtcaga tatttgtgag gatctagttc
     5821 aaagagggca tgaggtggct gttttgacag ggattcctaa ctatcctgag ggggaaatat
     5881 atgctgatta tcgtaagaga aaaaaaagaa gagagactat aaatggtgtt gctatttttc
     5941 gttcatacac cattgctagg aggcaaaata ctttataccg tatattgaat tattttagtt
     6001 ttgctctttc ttctacgata ggtgttatat ttgggcgtta taaagcgaaa gatggctcag
     6061 attttgattg tgtctttgtc aatcaactat ctccagttat gatggcttgg gctggtatag
     6121 cttataagaa caagtacaat aaacctatgt ttttgtattg catggatgtt tggccggata
     6181 gtttaattgt aggtggggtg aaggaaaatg gattgattta caagatattt gaatttgttt
     6241 caaaaaaagt atatcaagcc agcgattata tatttgttac tagtctatct tttaaagatt
     6301 attttgtaaa aaaatttaat attcctctcc acaaaattac ttacttacca caatatgcag
     6361 aggatttatt tgtaccaaat gaattaaaaa cgaacaaaaa tactattgac ttaacttttg
     6421 ctggaaatat tggaaaagct cagaatttag agactatttt gaaagcagcc agtgcaatag
     6481 aacagattcc cgatttagca aagagagttc attttcattt tgttggagat ggtacggaac
     6541 tattaaatat gcaaaaatta gcatgtgaac tagaattaga gaacacttca ttttatggta
     6601 gacgtccatt agaagagatg ccggattttt atacaaaatc agatgcgatg ctagtttctt
     6661 taataggcga ctctataatt tctcgcacct taccaggcaa ggtacaatct tatatggcgg
     6721 caggaaaacc aattatagga gcgatttcag gagatactca gagagttgta aaagaagcaa
     6781 aatgtggttt cataagtccg gaagggaatg ttgatcagtt agtgagaaat attcgtaagt
     6841 tctgtttgct ttctgtagag gaaagagaga aactaggaag gcaagctcgt tgttattatg
     6901 aagaacagtt ttcgaaagag tggtttatga catacttaga aaatcattta aaagaggggt
     6961 ttctatcatg aaggttttaa tgattaattc cgtttgtggt attaggagca ctgggagaat
     7021 ttgtgcagat ctcgcaactg ctttgacaga agaaggatat gaggttaaaa tcgcctatgg
     7081 tcgtgagtat gttccgaaac aatttcaaca gtatgcagtg aaaattggta caaagtctga
     7141 tattcgtttt catgcgattc gttctcgatt atttgacgaa tctggctttg gaagtagaca
     7201 ggcaactgtt aattttatta aatggatgaa agagtttgat cctgatatta ttcatctcca
     7261 taaccttcat gggtattata tcaatgttga actgttattt gattatctcc gaatatgcgg
     7321 taaaaagatt atatggactt tgcatgattg ttgggcattt acaggacact cggcttattt
     7381 tgattgtttg gaatgtgagt caaagggagt ttgtgaccat ccatctcaga aaaatgatta
     7441 tcccaagtcg ttcgtgaatt tttcaaagcg aaattatcaa agaaagaaaa aatgttttac
     7501 tcatattcct aatctcacta ttgttactcc gtctcaatgg ctagctaatt tagtaagaca
     7561 gtcattttta aaagaatatc cagtgaaagt aattcataat ggtattgata ctactgtctt
     7621 tcaaccgagg ctaatagccg ctcaaaaatt gagaaaaaga caccatcttg aaggaaagca
     7681 ggtactgctt ggtgtggctg ctatctggga taatagaaag ggattttctg atatgttagc
     7741 gctcgcgaat gatctaactg ataatcagag aatagttttg atagggttaa aagataggca
     7801 actcaaagaa ctacccaaag ggatcattgg gttaacagaa actaatagcc cagaagagtt
     7861 ggtagcatgg tatacactag cggatgtatt tctaaatcct acttatcaag ataattaccc
     7921 gacaactaat ttagaagcta tttcttgtgg gacaccagtt atcagctatc cgacaggtgg
     7981 tagtgtagaa agtgctaaac tttatggtct cgtttgtcag gatagaaacg tagcttctat
     8041 tttatcttcg ttagaaaaag tctctcagct atctaaaaca gaaaaattgg atttttcaat
     8101 tgcaagtttt attaaacaaa tgaaatattt atattagaac ttgaattata ggaaaatgag
     8161 gaatttgcat taaaatgatg aaaagaattt attatcacct tttggctatt tgggcttgga
     8221 ctcttccaaa ttcttatgct tttattgatt cgttaaaggt gttttttccg aatattagct
     8281 tacaaattgc aggttctctt ttggctgttg tctcaatagg aatttttatc actagaatat
     8341 attatacaag atatgaagtt tttatatctc tattggtttg tatttctatt ttaatttttt
     8401 attcaactcg ctttttttat tcgactaacg tagagttgta tcagtctttc ttcaattcct
     8461 ttctgattcg tccagttcct gcgatattag tagcgatgct gttagctaag aataatcata
     8521 taaaaggttt cataaaatgg tcagaaccta tgatgctttt ctatacattg acatcatttt
     8581 tagcagccct atctcctaga aacagcatta ttacttacca atctttatct tattatgcca
     8641 tgacagctta tatgattaat gtgtttaata ttatatacaa agagaaaata ttggaggagc
     8701 aactgacgta tttcagattc tcagcgtgga attttattag atatttttta cttttgattc
     8761 aagcttttaa tgcactctca ggaggtggga gaggtgcctt tattttatta attattttta
     8821 caggaatatt attaataaga actgctatga aatttaagtt ccttttctca tttattggag
     8881 gcctgtctgc tatagctcta gttgtttttt ttacaaaagg tttggatttg acatggctct
     8941 tgaatatgga cggtggagag cgattgttga acttcttcgg cagacctgaa catatatcta
     9001 cagataatag actattgatt tatgatactg tttggtctgc aatacaggaa aaaccctttt
     9061 taggatgggg agttggttca acttttttaa aatttaatgg atattcacat aatattgtat
     9121 tggatttatt gcatgatatg ggaagttttg gtttattaat tattctttcg gctttctttg
     9181 cttcttcagt aatattgtac aaattacgta aaatagattg gaaagtgaat ttatttattc
     9241 tgatgtttct agaagtatat gttcacatga gtttcagtgg aagctatctt gcagatggta
     9301 gactatggtt tttggtgatc tttacttatt gttactacag gtggaaagtg caggaaaagg
     9361 atgaagttag caattttatt atctgatatt tcaaaaatag gaggagtgca gcgtgtcacg
     9421 acagctcttg ttaatgaact ttgtcaaaat atagacgtta caattatcag catcttttcg
     9481 gaaaatgagc taccagcttt tggactttca gatagagttc aggtgagcta tcttttgaaa
     9541 gaacatgtta atttgaagaa gaattttttt aaagttagtg gagctttgcg aaaagtgttg
     9601 aaaaaacagc agtttgatgt tgttttatcg tcaggaactg gtctagtatc ctttctttgg
     9661 tttgctagtt tgggaattcc taccagactt ttggcatggg aacatcagtg tttttacttt
     9721 gggagatcgt ttggtctaga gtggttgggg cgaaagctag cctgtcgttt tgctgagagt
     9781 attgttgtct tgactaaaaa agatgaagga ttttacaaag agaatcgtcc taaggctcat
     9841 attgaacaaa tctataatat cctagacatg gattcacaaa cagctaagtg tcagctctct
     9901 tctaaaaaaa ttatcagtgt tggatcttta gtacgacaaa aaggttttga tctggctctt
     9961 gaggtagcta gtcaaataca attaagttat ccagattggc agtgggacat ttatggtgat
    10021 ggccccgata gagaaaaatt agaggagaaa gtcagggaat accaattaga aggctttata
    10081 aatttgaaag ggcttgttca gaatgttcgg gagctctatc ctgactactc tatctacgcc
    10141 ttgacatcac gatatgaagg attatcaatg gtattattag aagctaaaaa ctgccagatg
    10201 cctgctattt catttgattg taactgtgga ccctctgata ttatttcaga tggaagaaat
    10261 ggttttttga ttgattgttt tgatgtaaat atctatgcaa aaactttatc taaattaatg
    10321 actagtttag agttgcgaga acaagttgca aaatcgagtg ttattccagc agaagaattg
    10381 tcaacaactt atatcctaga taagtggaac aatctattaa agatagaaag aagataatat
    10441 gaaaatagtc catgtagaag atttttttca tccagatgca ggttaccaga ttaatgtttt
    10501 accaaaatat ctagcaaagt ttggtcatga acaagtgatt atcacttcag aaatggataa
    10561 aatccccgat aatcttaccc aattttttgg acgagaaaat atagaagaga gagatagaag
    10621 ttacgaagag aagcatcatg tgaagattat tcgcttgcct cttcatggat ttgtaagcgg
    10681 acgtgcgatt ttttctggaa agcttatttc ggctattaag ggtctttctc cagaggtatt
    10741 gtatattcat gggaatgaca ctttaacagg gattcgtctc cttttagctc gaaagaaact
    10801 taattgcaga atcgtcaccg atagtcatat gcttgaaatg gcatcaagaa atcctttcaa
    10861 caactacttt aggagatttt ataaaacctt gattactccc attttgataa aagaacagat
    10921 accaattatt cggacgcaag atgataatta tgttgaaaaa cacttgggaa ttcctttatc
    10981 gcaagctcca tggatttctt atgggtcgga tacagcgttc tttcacgcag atagccagat
    11041 taaggaagat tttcgttctc agtatcaaat cgcttcagat gctcttattt gtgtttacgc
    11101 aggaaagtta gatgagcata agggtgggat gtttttagca gagtctctaa gtaaaaagtt
    11161 aaatacggag caaccaattg ttttcattat agtgggtaat acaaatggag agtatggaga
    11221 agctgtcgag aaaagtttct cccaatctga aaaccaaatt ttgcgctttc cgactcaaaa
    11281 atatcaaaaa ttagcacagt tttttcaggt agcagatttt gctttatttc ctaaacaatg
    11341 tagtttaagt ttttatgatg cacaggcctg tggtttacca gttttattgg aagataataa
    11401 tatcaacctc gatagaactt ctcattataa tggttggacg ttcaaggcta acagcaaatt
    11461 aagtttgaga gattcattaa aaatgattgc gagtctagat aaagagaaga gacaagagta
    11521 ctctcagaat gcactgcact atatccttga acattataat tatgaagata aagcaagaga
    11581 atatgaaaag attcttatag gggaacgtac gaaatgagat agttaatatt tcgttatttt
    11641 ataggaaagg tggatttaat gaaaatttgc attgtttcag tcggagtggg cggactaccg
    11701 attccagctg taaaaggggg agcagtagaa aatctcattg ataattattt aagttacaat
    11761 gagaaatata atcatgatga aattacggtc gttagttgtg accataagga ggcgcgtgag
    11821 gcttcaaaaa aatacaagta tgcccaattt gtctatatag atattcattc acttaaatat
    11881 aaaataaaca aaacaatacg ttatgccatt aataaatatt cacctttctt cgtagggaac
    11941 gcttatatca gtcaattgcc agacttgtct ggttttgata cagttttgat tgaaaatcgc
    12001 cctgaatacg gttattatat tcgtaaaaag tttaaaggaa atcttgtttt acatcttcac
    12061 aatgatttat taatggacaa tgagtattct gtagattata gcgtttatga taaaattatc
    12121 acagtatctg actatattag gaataggtca gaagtagtaa cgtcaggtgt tccgatacag
    12181 actgtctata atggtattga cacagaacct tttttgcaga atttctctga agttgattta
    12241 tcagatctta aaaatcagtt ggaaattttg tcggatgatt ttgtgattgt tttttttgga
    12301 cgtatcaaca aaaataaagg tatcaaagaa ctgcttgaag ccttcttgtt gctaccaaag
    12361 aatttgaata taaaattact agctgttggt agttctatat ttggtcagac ggagttggat
    12421 actttcacaa cagagatacg gcaattggca aaacaagcat cagataaagt tgtttttaca
    12481 ggctatgtta attacaaaga cattcctaag tatcatcata ttgcagattg cattgttgtt
    12541 ccatctattt gggaggaacc agcggctttg acggtctgtg aagctttgat atcagggaaa
    12601 tatgttatta caacagatac tggagggaca ccagagcttg tagctggcag tgatgccctt
    12661 gtggtagcaa atgatgagtg tatagttgaa cacctcaaaa cagccctatt gagtgtctac
    12721 caaaaaggga aatgctcttc ggttattact tctaatagag atagaggaac ctatttttct
    12781 attgaaaaat atggaagaaa cttacgaaaa gagctcacac aaaatgaaag aattattaac
    12841 atatgagtcg tgtaaaaaat agttttttta atattttagc tggaatagtt ggtactatca
    12901 tatcgagtgt tttagctttc atagttagaa cagtgtttat ccgagttttg ggagagactt
    12961 atctaggttt caatggtcta tacaccaata tcttaacagt tttatcccta actgaattag
    13021 ggatcggatc atcaattgct tatttgatgt acaaaccttt agcagaaaaa gatggggaca
    13081 aattagctca agtagttcaa ttctataaaa aaatatatcg agtgattggt atcattattc
    13141 ttattttagg tttgtgtctc gttccttttt taccagtcat tgtaaattta aaaaatgcag
    13201 aagatttgaa ctatacagca ttgtatttgc tttatttagc agatacagtt tctacttatc
    13261 tattctttgc atataaaaga ggggtattgg ctgctgatca aaagatctat gttgcgaata
    13321 tctttgatat aattataacg acaattttat ctattttcca aattatcact ttgatgattt
    13381 ttaaagactt ttatctatat attattttaa aaattgctaa aaatcttact ttgaacctag
    13441 taattagttt aaaagtagat aaaatgtatc caagtattca taaatttaaa gggatagctc
    13501 cgcttccaaa aatggaaaga cgactagttt ggaaaaatgt atatgctacc tctgttcgac
    13561 aaatctttaa cgaattaatg aattcaacag atagtatagt tatttccatt gtcttaggaa
    13621 tagttatggt tggtaagtat tcgaactatg cttatatttt atcaatcgta tatattttct
    13681 ttggaggaat ttttaatccg attcaggctt ctattggaaa cctatctctg ttagcttcta
    13741 tagagaaaaa aaatgaaatc ttcaatagat tacgttttat aaattttttc tttttatcat
    13801 tttgctcaag ttgtcttcta gtattggtaa atccttttat cactatttgg attggagaaa
    13861 attacacttt atcatttaca ggtgtgattg caatagttgg tatgttattc gttagacaaa
    13921 ctggaaattg tacaaccatt tttcgtttgg gagaaggata ttttagagat tatcattttt
    13981 ctcctttaat cgcgggcatt ttaaatttag ttgtttcagt aattttagtg aattatatag
    14041 gtattgcagg tgtttttgtt ggaacaatgt taggatttgg tttccaattt atactggtgg
    14101 atacaattgt tacttataaa aaagtactta gtcgtccact atcagagttt tatttaagat
    14161 ggttgcagac gatcttatta actgtaggtt tatgtattgc gagttactat ttatctcgat
    14221 tggttagagt gaatagtata tatgatttga tactgttgtt tgtagtggtt attggattta
    14281 atttttttgc tttatgtttt atttattggc gaaatgatga ttttcaatat tttattcaat
    14341 tggttaaaaa ttttatgaaa aatttggagg aaaaaaatca tgattaatgt aatcggatta
    14401 ggttatattg gattgccaac aattttaatg ttggcaacaa acggcgtgaa agtagttgga
    14461 actgactaca atcaggattt ggtgagaact ttaaatgaag gtcaaacaac ctttaaagaa
    14521 gatggattgg atgaactatt ccataaagca gtggagtcgg gtgtggactt tacaaccgaa
    14581 tatcaacaaa cggataccta tattatttcc gttccaacac catatgactc cttctctaaa
    14641 aaaattgatc caagctatgt gattgaagct acgaaaacgg tacttgataa ttgcaataaa
    14701 ggagcggtta ttattattga atcgaccgta tcaccaggaa cggttgataa atttattcga
    14761 cctgttgtag aagaaaaagg ttttgttatt ggtagtgata ttcatcttgt ccatgctcca
    14821 gaacgtatta ttccagggaa tatggtctat gaattggtga ataataaccg tacaattgga
    14881 gctgatgacc tagaaatcgg ctataaagtg aaagagcttt atgcttcatt ttgtaagggc
    14941 gatattgttg ttacagatat tagaactgcg gagatgacca aggtagtaga aaatacattt
    15001 agagctgtaa atattgcttt cgctaacgaa ttagcacaga tctgtagtta tgataatatg
    15061 aatgtttatg aaattatccg gatctgtaat atgcacccac gggtaaatat tctacaacct
    15121 ggacctggtg ttggtgggca ttgtatttct gtggatcctt ggttcttagt tggagattat
    15181 cctgagttga caaatgttat tgaacattct atgcgaacaa atgctgccat gccagaattt
    15241 gtattaaatc gtatctatac cattatgaac gaacatcatc taacagatat tagtcgggtt
    15301 ggtctatatg gtcttaccta caaagagaat gtagatgata tgcgtgaatc tccaacgctt
    15361 cagttattag aatctatgag ccgccatctg gcaacacctg ctattaaagt atatgatcca
    15421 tttatagaaa aagatgttgt ggcgaatcag tcacatgatt tagatgaatt tttatctaat
    15481 gttgatattg ttgtactgtt ggttggtcat gatgagattt tacaaaatat ggataaacta
    15541 aaagataaga tagtgttaga tacacgttat atctgtcatc ttgatggaac ttacagatta
    15601 taattagtga taaataaagt aaggattgac tatgaaaaaa atagttgtaa ttttcggaac
    15661 tcgtcccgaa gctatcaaga tgtgtccctt ggttaaagag ctaagaacac gtgagaatct
    15721 tgaaacattg gtctgtgtta cgggtcaaca tcgtcaaatg ctggatcaag ttttggatac
    15781 ttttaggatt acgcctgatt ttgatttatc tattatgaag gacaaacaaa ctctctttga
    15841 tgtcacaatt ggcattttgg aaggcatgaa gactgtctta gagtcagtta atcctgattt
    15901 aatattagtt catggggata cgagtacaac atttgccagt tcactggccg ccttttatct
    15961 acagattcca attggacatg tagaggctgg tttgcgtact tatgatattt attcacctta
    16021 tcctgaagaa tttaatcgtc aagcagtagg tgctttggct cagtatcatt ttacaccaac
    16081 acaactctca aaagacaatc tcttgagaga aggaaaaaat tctgaagcta tatttatcac
    16141 aggtaacaca gcaattgatg ctttacaaac tacaattcaa gaggattata ctcatcctga
    16201 gttaaattgg gttggggata gcaaactaat attaattact gctcatcgtc gtgaaaatat
    16261 tggtgacccg atgaggcaca tgtttagagc aatccgacgt atcattgaag aacattcgga
    16321 tataaaggct ctttacccca ttcatatgaa tcctctagtt cgtcagattg ctgaggaaga
    16381 actaagcgga tgtgaacgta tcaaaatgat cgatccgttg gaagtattag attttcataa
    16441 ctttttatca cggagttatc tcattttaac agatagtggt ggtatccaag aagaggcacc
    16501 tagtttagga aaacctgttt tagttatgag agatacaact gaacgtccgg agggaattaa
    16561 agcaggaact ttgaagcttg taggtactga tgaggacaat atttatagac attttaaaga
    16621 attgttagaa aatgatttag tttatcaagc gatgagccaa gcttcaaatc cgtatggaga
    16681 tggaacagct tgcaagaaaa ttgcagacat actagaagga gaagtataat atatgtcaca
    16741 atttacagga aaaactctcc taattacagg aggaacaggt tcatttggta atgctgtcct
    16801 taatcgtttt ttacagactg atattggtga aattcgtatt ttttcccgtg atgaaaaaaa
    16861 acaggatgat atgcgtcatg agtttcaggt aaaagtacca gaagtagctg ggaaaatccg
    16921 tttttacctt ggagatgtgc gtgacttagc ttcggtaaaa aatgctatgc atggtgtgga
    16981 ttatgttttt catgctgctg ctcttaaaca agtaccttcg tgtgaatttt tccctgtaga
    17041 agcggtaaaa actaacattt tgggaacgga gaatgtcctc actgcggcta tcgaagctgg
    17101 tgtaaagcaa gttatctgtc tttctacaga taaggcggct tatcccgtca atgctatggg
    17161 aacatccaag gctgatggaa aagattgctg ttgctaagtc caggacggta aatcctgagc
    17221 atacaaagat atgtgtgact cgctatggga atgttctgtg tagccgtgga tctgtcgttc
    17281 ctctttggat tgagcaaatt aagcaaggaa atgctcttac aattactgaa cctagcatga
    17341 cacgttttgt gatgacatta gaagaagcag tagacttggt tttatttgca tttgaagaag
    17401 ggaaatctgg agatatacta gttcagaaag caccagcatg tacgattgaa gtgttggcta
    17461 aggctgtatc agaaattttt gcctcagaac aagatattaa gattataggt attagacacg
    17521 gagaaaaaag gtatgaaaca ctattaacta atgaagagtg cgcaaatgca attgatttgg
    17581 gtgattttta tagagttcct agtgataatc gtaatcttaa ctatgataag tatttcaaag
    17641 atggtagtac gaatagaaat ttgttgacag aattcaatag taataatacc gatttgatgg
    17701 atgtagagca agttaaaaga aagttgctag aattagatga aatacagaca gcaattcgtg
    17761 atatggtagc agatgaagag atgtaaaatc ttttaagata cattaaaatt atcaaggata
    17821 tataatgtat catgtattgt cgagagagtt gactattaaa acagcatata aaacaaggag
    17881 ggggcatgat taaaaatatt ttaatcacag gagcgaaagg atttgtagga aaaaatctta
    17941 tctgtactct ggaagctttg aaagatgggc gagataggac tcgtcctaat ttagagattg
    18001 gagagatttt tcagtatgat cgtgatacag atccgatttt attagatgaa tattgtaaga
    18061 aggccgattt cgtattccat ttagctggtg tcaatcgtcc acagaatcct gatgaattca
    18121 tggagggaaa ttacggtttt tcaagtagat tattggagat tttagaaaag tatgaaaaca
    18181 cttgtcctgt tctactctca agttctactc aagctagttt agaaggccga ttttcaaact
    18241 ctatatatgg acaatctaag ctagcagggg aagaactctt ctttgaatat ggaaagaaaa
    18301 cgggagcacc tgtcttagtt taccgtttcc cgaatcttta tgggaagtgg tgccgtccta
    18361 actacaattc tgctgtagca actttctgtc ataatctagc tcacgattta cctattcaag
    18421 taaatgatcc aagtgtagaa ttggagttgc tgtatattga tgatttgata caagagtgtc
    18481 taactgcatt ggaaggaaat cctcatcgtt gtaatctaga tggattacaa atcttaccta
    18541 gcccatcagg aaactactgc tacgtaccaa cgactcatcg tgcaacctta ggagagattg
    18601 tctctctatt agaaacattt aaaaaacagc ctaatagttt agttatgcct gaaattcctc
    18661 aaggatcgtt taaaaagaaa ttgtattcta cctacctatc ttatttacca gtagataagt
    18721 ttaggtttcc tctaaaaatg aatatagatg aacgaggtag ttttacggaa ttattaaaaa
    18781 cagaaaatac gggtcaattt tctgttaata tttctaaacc tggcattacc aaagggcaac
    18841 attggcatca ttctaagtgg gaatttttca tggttgtttc tggtcgtgct ttaatacaag
    18901 agcgtaggat agggctggat gaaaacggtc aagagtatcc tattctgaac tttgaagtgt
    18961 cgggcgataa gattgaagca atacatatga taccgggcta tgcacataat attattaatc
    19021 tttctgatac agaaaatcta attactgtca tgtgggctaa tgagtcattt gatcctagac
    19081 atccagatac tttttttgaa caagtggaga aataaatgaa aattaagaca gattatagtg
    19141 atattcattt taaagataat ggcaaactta agttattgat tattgtggga acacgtccag
    19201 agattatacg tctaagtagt gttatcacta aatgtcgaaa gtattttgat gttattttgg
    19261 cacatactgg acaaaactat gattacaatt taaatggtat tttctttgat aatttagggt
    19321 tagacactcc ggacgtatac atggatgctg ttggagatga tcttggtgct actgtaggga
    19381 atattattaa tacttcatac aaattgatga atcaaattaa accagatgct ttattgattt
    19441 taggggatac aaattcttgt ttatcagcta ttgctgccaa gcgtttacat attccaattt
    19501 ttcatatgga ggctggcaat cgctgtaaag atgagtgcct gccggaagag actaatcgtc
    19561 ggattgttga tattatttca gatgttaact tagcatactc tgaacatgca cgtaagtatt
    19621 tacatgagtg tggtttacct aaagagcgca catatgtaac tggttctcct atggcagaag
    19681 tgttacataa aaatttacct gccattgagt cttcagatat ccatgaacgt ttgggattga
    19741 aaaaaggagg ttatatctta ctttcagctc accgtgagga aaatattgat acagataaaa
    19801 attttatttc tctctttaca gcaattaatc aattagctga aaagtataat atgccaatct
    19861 tatattcttg ccatcctaga tcaaagaaaa ggctacaaga gagcggtttt aaactagata
    19921 aacgtgtgat tcagcatgag ccactaggat tccatgacta taattgttta cagatgaatg
    19981 catttgttgt agtatctgat tcgggaactt taccggaaga aagtagtttc tttactagtc
    20041 aaggttatcc ttttcccgct gtatgtattc gtacaagtac agaacgtcct gagtccttag
    20101 ataaggcagg atttattttg gcaggcattg atgaaaattc tcttcttcaa gcagttgaaa
    20161 ctgctgttag cttggcagaa gatgaggatt ttggattacc ggttccagat tatgttgagg
    20221 aaaatgtctc tactaaagtt gttaagataa tacagagcta tacagggata gtggataaaa
    20281 tagtttggag gaaaagctga attgtatatt tttaataaat caaaacgaga tgattaattc
    20341 ttagtagaac aagagtaaaa ttgaacgtat ttgatggaaa tgtcttactt gatagtcgag
    20401 ggatagccat tctatcggat ttttggcttg tttttgcgct tcatgtttga tagaataaag
    20461 ggctctttgt caactgtagt gggttgaaga aaagctaagc ttgagaaagg acaaatttcg
    20521 tcctttcttt tttgatgttc agagcgataa aaatccgttt tttgaagttt tcaaagtttc
    20581 gaaagtaacc gcccaataac gaagtatatt gaaaaatctc cagactagag aactcacgga
    20641 tagttcctaa tctggagatt tcttatttgc acttttcttg tacaacttta gtccatggta
    20701 aataagcctc taaaacctct ttgtttacga gagtttcctc gtttggaaga cattctagaa
    20761 gataggatag atatttctca ctatttagtt gatgacgttt agctgtttcc aacaagctca
    20821 taataatagc tcttgcttta gctccttcaa aactttgaga aaataaccac cctcgctttt
    20881 ttaaactgag ctcaggctaa aagagtccac tggactcttt tactccgtcc cataaccaat
    20941 gatttaatgg cgcgttcagc tagattattg gaaaggacca gatgtccgtc tttcaaaata
    21001 gtcttaaagg tttcttcata cttgaggctg tattcaattg cccttcctag ttttgaacct
    21061 gctaaaactg actgacggcg gcaccaagca aagaagtctt ccattagggg ctggagatgt
    21121 tcttgacgtt tctgtagtcg ttcatcagct ggcaaagcct cccagtctct ttccaaggaa
    21181 aataactgat cacaataagc taaaccttta gctcctaagg atgatttatc tgcttgcttg
    21241 ggggtcgctt caaaaaattt ccttctcaca tgcgcccaac atccaacaag ttcagcttct
    21301 tccagttgac gataagcttc tagcggttcg tagtttacca agcttagcgt cgccttgctc
    21361 ctaaaccttg gactgctatc gcataggcag aactagagga ctaaagtcct aagttactgc
    21421 cgcaacatat cacaatgaac atagccagaa taatctccta ggaattcttg tactaccgaa
    21481 ccactccgac tctgatcatg atggtacagc gtgattgctt gattctcaac tttcccagac
    21541 aaaaaggtcc aatagtaggt cagatggcta tgactctcta gaacccgata agaagtttca
    21601 tccgcatgaa gtaagggctg agtcaatagt ctctctcgca agaggttata aaggggcttt
    21661 aggaatagga gctttcacaa gcttatccag atgattatct tttactcgtt atggacaatg
    21721 ctatatggca taaatcaagt accttaaaga ttccgactaa tattggtttt gcatttattc
    21781 ctccatacac accagagatg aaccccattg aacaagtgtg gaaagagatt cgtaaacgtg
    21841 gatttaagaa taaagccttt cgaactttgg aagatgtcat acaaggactg gagaaggagg
    21901 tgataaagtc catcgttaat cggagatgga ctagaatgct ttttgaaagc agatgagtgt
    21961 aaaaagaaag tcctcatttc aatagaaatc acgactttct gatgaattta tagtgaaatg
    22021 aaataagacc aggacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
    22081 acagaggtgt actattctag tttcaatcta ctatattttt ggagtgatag aaaagccctt
    22141 catcagccaa tctacttgtt caggtgcgag agctttgaca tccttttctg tactgggcca
    22201 agtcagtctg ccgttctcaa agcgtttata tagtagccaa aatccttgac catcccagta
    22261 aagggcttta aagcggtctt tacgtccacc acaaaagaga aaaacttgac ctgagaaaga
    22321 atccaattca aagtgggttt taaccagata agccagtgaa tcgattcctt gtctcatatc
    22381 cgttttccca catacgagat agacctgccc taggctagat agatgaattg tcatagagca
    22441 acaccttatc caaaagctgt tctatcattt cgagattgag agattgaaaa aaacttactt
    22501 caagcttgcc aatacgaatt ttaagcagaa tatcatttct ctttttagaa tcaaaaggac
    22561 gagattgtgg aatctctaca ggaacaatag gttgtagcat taaaatatcc tccaatagtt
    22621 ttactttact aatagtatac aggaggagct ccatgaatga tagatacctt gttatgacgc
    22681 gcttactaaa caactaactg atgcacgatt taagcgcctt gttggtgttc agcgcacgac
    22741 ttttgaagag atgttagctg tattaaaaac agcttatcaa cttaaacacg caaaaggtgg
    22801 acgaaaacct aaattaagcc tagaagacct tcttatggcc actcttcaat atgtgcgaga
    22861 atatcgaact tatgaagaaa ttgcggctga ttttggtatc cacgaaagca acttaatccg
    22921 tcggagccaa tgggttgaag taactcttgt tcaaaggtgg tgttacgatt tcaagaactc
    22981 ctctcagttc tgaggacacg gtaatgattg atgcgacgga agtaaaaatc aatcgcccta
    23041 aaaaaagaat tagcgaatga ttctggtaaa aagaaatgcc acgctatgaa ggctcaagcg
    23101 attgtcacaa gtcaagggag aattgtttct ttggatatca ctgtgaacta ttgtcatgat
    23161 atgaagttgt tcaaaatgag ttgcagaaat atcggacaag ctggaaaaat cttggctgac
    23221 agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg taaatccagc
    23281 aaactcaatc cgctaacagc taaagataaa gcctgtaacc atgcactatc taaggataga
    23341 agcaaggttg agaacatctt tgccaaagta aaaacgttta aaatgttttc aacaacctat
    23401 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggtat tatcaatcat
    23461 gaactaggat tctagttttg caggaagtct attgaaggat cttttgcttt agttccttgg
    23521 tcaaggttga ttattttcac ggagcgcttc cgattgtttt cataaaccat ttgcgcatag
    23581 tcagcagaat aaatcttttt gaaacgtccc tttcctagac attatagaac tttcagattc
    23641 atctgaattt accaaattaa cacaaaaatt ctgaaaattc tgttgacatc tttctgaaaa
    23701 gagtttataa tggagagaaa gttttaaagg agaaaatgat gaaaagttca aaactatttg
    23761 cccttgcggg cgtgacatta ttggcggcga ctactttagc tgcatgctct ggatcaggtt
    23821 caagcactaa aggtgagaag acattctcat acatttatga gacagaccct gataacctca
    23881 actatttgac aactgctaag gctgcgacag caaatattac cagtaacgtg gttgatggtt
    23941 tgctagaaaa tgatcgctac gggaactttg tgccgtctat ggctgaggat tggtctgtat
    24001 ccaaggatgg attgacttac acttatacta tccgtaagga tgcaaaatgg tatacttctg
    24061 aaggtgaaga atacgcggca gtcaaagctc aagac
//
