LOCUS       CR931719               25070 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain Eddy nr. 73 (serotype 46).
ACCESSION   CR931719
VERSION     CR931719.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25070)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 25070)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..25070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Eddy nr. 73"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SCP46_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SCP46_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34602.1"
                     /db_xref="GOA:Q4K2R1"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K2R1"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVP
                     WDAFCVELL"
     gene            322..490
                     /gene="aliB"
                     /locus_tag="SCP46_0002"
                     /pseudo
     CDS             322..490
                     /gene="aliB"
                     /locus_tag="SCP46_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(488..808,810..1013))
                     /gene="tnp"
                     /locus_tag="SCP46_0003"
                     /pseudo
     CDS             complement(join(488..808,810..1013))
                     /gene="tnp"
                     /locus_tag="SCP46_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            1227..2681
                     /gene="wzg"
                     /locus_tag="SCP46_0004"
     CDS             1227..2681
                     /gene="wzg"
                     /locus_tag="SCP46_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34605.1"
                     /db_xref="GOA:Q4JYN0"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JYN0"
                     /translation="MLIMSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNI
                     FAFRYLNLVVTVLVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGL
                     TNRLNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNT
                     DLTVNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKV
                     EAPKTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPI
                     ADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVH
                     NDQEFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKL
                     TSTEALKNYSTIIDSLQNSIQTNMPLETMINLVNAQLESGGSYKVNSQDLKGTGRMDL
                     PSYAMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1227..1364
                     /gene="wzg"
                     /locus_tag="SCP46_0004"
                     /note="Signal peptide predicted for SPC1997 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 46 and 47"
     misc_feature    1440..1787
                     /gene="wzg"
                     /locus_tag="SCP46_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 2.3e-64"
     misc_feature    1965..2408
                     /gene="wzg"
                     /locus_tag="SCP46_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 5.7e-70"
     gene            2683..3414
                     /gene="wzh"
                     /locus_tag="SCP46_0005"
     CDS             2683..3414
                     /gene="wzh"
                     /locus_tag="SCP46_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34606.1"
                     /db_xref="GOA:Q4JYM9"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM9"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLVEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIEENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLEQDLVHAIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    2686..3294
                     /gene="wzh"
                     /locus_tag="SCP46_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 7.8e-36"
     gene            3420..4115
                     /gene="wzd"
                     /locus_tag="SCP46_0006"
     CDS             3420..4115
                     /gene="wzd"
                     /locus_tag="SCP46_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34607.1"
                     /db_xref="GOA:Q4JYM8"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM8"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILLVALVTGAGAFAYSAFI
                     VKPEYTSTTRIYVVNRDQGDKSGLTNQDLQAGTYLVKDYREIILSQNVLEKVATNLKL
                     DIPAKTLARKVQVTVPVDTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDV
                     TTLEEARPATTPSSPNVRLNSLFGFFGGAVVTVIAVLLIELFDIRVKRPEDVEDVLQI
                     PLLGVVPDLNKMK"
     misc_feature    3420..3536
                     /gene="wzd"
                     /locus_tag="SCP46_0006"
                     /note="Signal peptide predicted for SPC1999 by SignalP 2.0
                     HMM (Signal peptide probability 0.729) with cleavage site
                     probability 0.460 between residues 39 and 40"
     misc_feature    3441..3857
                     /gene="wzd"
                     /locus_tag="SCP46_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1.5e-54"
     misc_feature    3963..4040
                     /gene="wzd"
                     /locus_tag="SCP46_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4125..4799
                     /gene="wze"
                     /locus_tag="SCP46_0007"
     CDS             4125..4799
                     /gene="wze"
                     /locus_tag="SCP46_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34608.1"
                     /db_xref="GOA:Q4K1Y2"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4K1Y2"
                     /translation="MPTLEISQAKLDFVKKAEENYNALCTNLQLSGDDLKVFSITSVK
                     QGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITQKCDASILVTKAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGKK"
     gene            order(5073..5498,5510..5887)
                     /gene="tnp"
                     /locus_tag="SCP46_0008"
                     /pseudo
     CDS             join(5073..5498,5510..5887)
                     /gene="tnp"
                     /locus_tag="SCP46_0008"
                     /note="member of homology group 148"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
     misc_feature    order(5406..5498,5510..5878)
                     /gene="tnp"
                     /locus_tag="SCP46_0008"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 1.1e-10"
                     /pseudo
     gene            6019..6618
                     /gene="wciI"
                     /locus_tag="SCP46_0009"
     CDS             6019..6618
                     /gene="wciI"
                     /locus_tag="SCP46_0009"
                     /note="member of homology group 29"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34610.1"
                     /db_xref="GOA:Q4JYM6"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM6"
                     /translation="MYREIKRLGDILLSFIGIIVLFPVFIIIAIAIKLDSKGPVIFKQ
                     KRFGLHKKSFYVLKFRTMKVESPKYVATRDLDKPEQWITKVGACLRKTSLDELPQLWN
                     ILVGDMSVVGPRPVAINELDLIKEREQYGANDILPGLTGWAQINGRDNLSTEMKAEID
                     GYYVKHMSLRMDLRCILRTIPYVLKRKGIVEGSGKKELE"
     misc_feature    6019..6111
                     /gene="wciI"
                     /locus_tag="SCP46_0009"
                     /note="Signal peptide predicted for SPC2003 by SignalP 2.0
                     HMM (Signal peptide probability 0.855) with cleavage site
                     probability 0.449 between residues 31 and 32"
     misc_feature    6034..6588
                     /gene="wciI"
                     /locus_tag="SCP46_0009"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 1.4e-36"
     gene            6584..7849
                     /gene="wciJ"
                     /locus_tag="SCP46_0010"
     CDS             6584..7849
                     /gene="wciJ"
                     /locus_tag="SCP46_0010"
                     /note="member of homology group 35"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34611.1"
                     /db_xref="GOA:Q4JYM5"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM5"
                     /translation="MWRVVVRKSWSDAMKILFVCQHYKPEPFRLSDICEDLVQRGHEV
                     AVLTGIPNYPEGEIYADYRKRKKRRETINGVAIFRSYTIARRQNTLYRILNYFSFALS
                     STIGVIFGRYKAKDGSDFDCVFVNQLSPVMMAWAGIAYKNKYNKPMFLYCMDVWPDSL
                     IVGGVKENGLIYKIFEFVSKKVYQASDYIFVTSLSFKDYFVKKFNIPLHKITYLPQYA
                     EDLFVPNELKTNKNTIDLTFAGNIGKAQNLETILKAASAIEQIPDLAKRVHFHFVGDG
                     TELLNMQKLACELELENTSFYGRRPLEEMPDFYTKSDAMLVSLIGDSIISRTLPGKVQ
                     SYMAAGKPIIGAISGDTQRVVKEAKCGFISPEGNVDQLVRNIRKFCLLSVEEREKLGR
                     QARCCYEEQFSKEWFMTYLENHLKEGFLS"
     misc_feature    7241..7774
                     /gene="wciJ"
                     /locus_tag="SCP46_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.7e-14"
     gene            7798..9015
                     /gene="wcxB"
                     /locus_tag="SCP46_0011"
     CDS             7798..9015
                     /gene="wcxB"
                     /locus_tag="SCP46_0011"
                     /note="member of homology group 55"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34612.1"
                     /db_xref="GOA:Q4JYM4"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM4"
                     /translation="MVYDILRKSFKRGVSIMKVLMINSVCGIRSTGRICTDLATALTE
                     EGYEVKIAYGREYVPKQFQQYAVKIGTKSDIRFHAIRSRLFDESGFGSRQATVNFIKW
                     IKEFDPDVIHLHNLHGYYINIELLFDYLRICGKKIIWTLHDCWAFTGHSAHFDCLECE
                     SKGVCDHPSQKNDYPKSFVNFSRRNYQRKKKCFTHIPNLTIVTPSQWLANLVGQSFLK
                     EYPVKVIHNGIDTTVFQPRLIAAQKLKKRYHLEGKQVLLGVAAIWTDKKGFSDMLVLA
                     SHLADNQRIVLIGLKDRQLKKLPKGIIGLTETNSPEELAAWYTLADVFLNPTYQDSYP
                     TTNLEAISCGTPVISYPTGGSVESAKLYGLVCQDRNVASILSSLEKVSQLSKTEKLDF
                     SIASFIKQMKYLY"
     misc_feature    8518..9000
                     /gene="wcxB"
                     /locus_tag="SCP46_0011"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 3.6e-12"
     gene            9053..10264
                     /gene="wzy"
                     /locus_tag="SCP46_0012"
     CDS             9053..10264
                     /gene="wzy"
                     /locus_tag="SCP46_0012"
                     /note="member of homology group 71"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34613.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM3"
                     /translation="MMKRIYYHLLAILAWTLPNSYAFIDSLKVFFPNISLQIAGSLLA
                     VISIGIFITRIYYTGYEVFISLLVCIFILIFYSTRFFYSTNVELYHSFFNSFLIRPVP
                     GILVAMLLAKNNHIKGFIKWSEPMMLFYTLTSFLAALSPRNSIIIYQSLSYYAMTAYM
                     INVFNIIYKEKILEEQLTYFRFSAWNFIRYFLLLIQAFNALSGGGRGAFILLIIFTGI
                     LLIRIAMNFKFLFSFIGGLSAIALVVFCIKDLDFTWLLNMDGGERLLNFFGRPERIST
                     DNRLLIYDTVWSAIQEKPFLGWGVGSTFLKFNGYSHNIVLDLLHDMGSFGLLIILSAF
                     FASSVILYKLRKIDWKVNLFILMFLEVYVHMSFSGSYLADGRLWFLVIFTYCYYRWKV
                     QEKDEVSNFII"
     misc_feature    9869..10036
                     /gene="wzy"
                     /locus_tag="SCP46_0012"
                     /note="HMMPfam hit to PF04932, O-Antigen Polymerase, score
                     1.1e-08"
     gene            10239..11315
                     /gene="wcxD"
                     /locus_tag="SCP46_0013"
     CDS             10239..11315
                     /gene="wcxD"
                     /locus_tag="SCP46_0013"
                     /note="member of homology group 72"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34614.1"
                     /db_xref="GOA:Q4JYM2"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM2"
                     /translation="MKLAILLSDISKIGGVQRVTTALVNELCQNIDVTIISIFSENEL
                     PAFGLSDRVQVSYLLKEHVNLKKNFFKVSGALRKVLKKQQFDVVLSSGTGLVSFLWFA
                     SLGIPTRLLAWEHQCFYFGRSFGLEWLGRKLACRFAESIVVLTKKDEGFYKENRPKAH
                     IEQIYNILDMDSQTAKCQLSSKKIISVGSLGRQKGFDLALEVASQIQLSYPDWQWDIY
                     GDGPDREKLEEKVREYQLEGFINLKGLVQNVRELYPDYSIYAMTSRHEGLPTVLLEAK
                     NCQMPVISFDCNCGPSDIISDGRNGFLIDCFDVNIYAKTLSKLMTSLELREQVAKSSV
                     IPAEELSTTYILDKWNNLLKIERR"
     misc_feature    10740..11246
                     /gene="wcxD"
                     /locus_tag="SCP46_0013"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 2.8e-33"
     gene            11317..12495
                     /gene="wcxE"
                     /locus_tag="SCP46_0014"
     CDS             11317..12495
                     /gene="wcxE"
                     /locus_tag="SCP46_0014"
                     /note="member of homology group 73"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34615.1"
                     /db_xref="GOA:Q4JYM1"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM1"
                     /translation="MKIVHVEDFFHPDAGYQINVLPKYLAKFGHEQVIITSEMDKIPD
                     NLTQFFGRENIEERDRSYEEKHHVKIIRLPLHGFVSGRAIFSGKLISAIKGLSPEVLY
                     IHGNDTLTGIRLLLARKKLNCRIATDSHMLEMASRNPFNNYFRRFYKTLITPILIKEQ
                     IPIIRTQDDNYVEKHLGIPLSQAPWISYGSDTAFFHADSQIKEDFRSQYQIPSDALIC
                     VYAGKLDEHKGGMFLAESLSKKLNTEQPIVFIIVGNTNGEYGEAVEKSFSQSENQILR
                     FPTQKYQKLAQFFQVADFALFPKQCSLSFYDAQACGLPVLLEDNNINLDRTSHYNGWT
                     FKANSKLSLRDSLKMIASLDKEKRQEYSQNALHYILEHYNYEDKAREYEKILIGERTK
                     "
     misc_feature    11920..12420
                     /gene="wcxE"
                     /locus_tag="SCP46_0014"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 9.8e-05"
     gene            12528..13724
                     /gene="wcxF"
                     /locus_tag="SCP46_0015"
     CDS             12528..13724
                     /gene="wcxF"
                     /locus_tag="SCP46_0015"
                     /note="member of homology group 74"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34616.1"
                     /db_xref="GOA:Q4JYM0"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q4JYM0"
                     /translation="MDLMKICIVSVGVSGLPIPAVKGGAVENLIDNYLSYNEKYNHDE
                     ITVVSCDHKEAREASKKYKYAQFVYIDIHSLKYKINKTIRYTINKYSPFFVGNAYISQ
                     LPDLSGFDTVLIENRPEYGYYIRKKFKGNLVLHLHNDLLMDNEYSVDYSVYDKIITVS
                     DYIRNRSEVVTSGVPIQTVYNGIDTELFLQNFSEVDLSDLKNQLEILSDDFVIVFFGR
                     INKNKGIKELLEAFLLLPKNLNIKLLAVGSSIFGQTELDTFTTELRQLAKQASDKVVF
                     TGYVNYKDIPKYHHIADCIVIPSIWEEPASLTVCEALISGKYVITTDTGGTPELVAGS
                     DALVVANDECIVEHLKTALLSVYQKGKCSSVITSNRDRGAYFSIEKYGRNLRKELTQN
                     ERIINI"
     misc_feature    12528..12602
                     /gene="wcxF"
                     /locus_tag="SCP46_0015"
                     /note="Signal peptide predicted for SPC2009 by SignalP 2.0
                     HMM (Signal peptide probability 0.717) with cleavage site
                     probability 0.447 between residues 25 and 26"
     misc_feature    13116..13643
                     /gene="wcxF"
                     /locus_tag="SCP46_0015"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.1e-25"
     gene            13721..15265
                     /gene="wzx"
                     /locus_tag="SCP46_0016"
     CDS             13721..15265
                     /gene="wzx"
                     /locus_tag="SCP46_0016"
                     /note="member of homology group 56"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34617.1"
                     /db_xref="GOA:Q4JYL9"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JYL9"
                     /translation="MSRVKNSFFNILAGIVGTIISSVLAFIVRTVFIRVLGETYLGFN
                     GLYTNILTVLSLTELGIGSSIAYLMYKPLAEKDGDKLAQVVQFYKKIYRVIGIIILIL
                     GLCLVPFLPVIVNLKNAEDLNYTALYLLYLADTVSTYLFFAYKRGVLAADQKIYVANI
                     FDIIITTILSIFQIITLMIFKDFYLYIILKIAKNLTLNLVISLKVDKMYPSIHKFKGI
                     APLPKMERRLVWKNVYATSVRQIFNELMNSTDSIVISIVLGIVMVGKYSNYAYILSIV
                     YIFFGGIFNPIQASIGNLSLSASIEKKNEIFNRLRFINFFFLSFCSSCLLVLVNPFIT
                     IWIGENYTLSFTGVIAIVGMLFVRQTGNCTTIFRLGEGYFRDYHFSPLIAGILNLVVS
                     VILVNYIGIAGVFVGTMLGFGFQFILVDTIVTYKKVLSRPLSEFYLRWLQTILLTVGL
                     CIASYYLSRLVRVNSIYDLILLFVVVIGFNFFALCFIYWRNDDFQYFIQLVKNFMKNL
                     EEKNHD"
     misc_feature    13721..13795
                     /gene="wzx"
                     /locus_tag="SCP46_0016"
                     /note="Signal peptide predicted for SPC2010 by SignalP 2.0
                     HMM (Signal peptide probability 0.819) with cleavage site
                     probability 0.398 between residues 25 and 26"
     gene            15258..16481
                     /gene="mnaB"
                     /locus_tag="SCP46_0017"
     CDS             15258..16481
                     /gene="mnaB"
                     /locus_tag="SCP46_0017"
                     /note="member of homology group 75"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmannosamine dehydrogenase MnaB"
                     /protein_id="CAI34618.1"
                     /db_xref="GOA:Q4K1X3"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q4K1X3"
                     /translation="MINVIGLGYIGLPTILMLATNGVKVVGTDYNQDLVRTLNEGQTT
                     FKEDGLDELFHKAVESGVDFTTEYQQTDTYIISVPTPYDSFSKKIDPSYVIEATKTVL
                     DNCNKGAVIIIESTVSPGTVDKFIRPVVEEKGFVIGSDIHLVHAPERIIPGNMVYELV
                     NNNRTIGADDLEIGYKVKELYASFCKGDIVVTDIRTAEMTKVVENTFRAVNIAFANEL
                     AQICSYDNMNVYEIIRICNMHPRVNILQPGPGVGGHCISVDPWFLVGDYPELTNVIEH
                     SMRTNAAMPEFVLNRIYTIMNEHHLTDISRVGLYGLTYKENVDDMRESPTLQLLESMS
                     RHLATPAIKVYDPFIEKDVVANQSHDLDEFLSNVDIVVLLVGHDEILQNMDKLKDKIV
                     LDTRYICHLDGTYRL"
     misc_feature    15261..15815
                     /gene="mnaB"
                     /locus_tag="SCP46_0017"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.4e-45"
     misc_feature    15837..16097
                     /gene="mnaB"
                     /locus_tag="SCP46_0017"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 4.5e-33"
     misc_feature    16179..16442
                     /gene="mnaB"
                     /locus_tag="SCP46_0017"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 2.5e-15"
     gene            16504..17607
                     /gene="mnaA"
                     /locus_tag="SCP46_0018"
     CDS             16504..17607
                     /gene="mnaA"
                     /locus_tag="SCP46_0018"
                     /EC_number="5.1.3.14"
                     /note="member of homology group 23"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine-2-epimerase MnaA"
                     /protein_id="CAI34619.1"
                     /db_xref="GOA:Q4K1V3"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q4K1V3"
                     /translation="MTMKKIVVIFGTRPEAIKMCPLVKELRTRENLETLVCVTGQHRQ
                     MLDQVLDTFRITPDFDLSIMKDKQTLFDVTIGILEGMKTVLESVNPDLILVHGDTSTT
                     FASSLAAFYLQIPIGHVEAGLRTYDIYSPYPEEFNRQAVGALAQYHFTPTQLSKDNLL
                     REGKNSEAIFITGNTAIDALQTTIQEDYTHPELNWVGDSKLILITAHRRENIGDPMRH
                     MFRAIRRIIEEHSDIKALYPIHMNPLVRQIAEEELSGCERIKMIDPLEVLDFHNFLSR
                     SYLILTDSGGIQEEAPSLGKPVLVMRDTTERPEGIKAGTLKLVGTDEDNIYRHFKELL
                     ENDLVYQAMSQASNPYGDGTACKKIADILEGEV"
     misc_feature    16573..17595
                     /gene="mnaA"
                     /locus_tag="SCP46_0018"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 2.5e-174"
     gene            17611..18666
                     /gene="fnlA"
                     /locus_tag="SCP46_0019"
     CDS             17611..18666
                     /gene="fnlA"
                     /locus_tag="SCP46_0019"
                     /note="member of homology group 36"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlA"
                     /protein_id="CAI34620.1"
                     /db_xref="GOA:Q4JYL6"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR013692"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYL6"
                     /translation="MSQFTGKTLLITGGTGSFGNAVLNRFLQTDIGEIRIFSRDEKKQ
                     DDMRHEFQVKVPEVAGKIRFYLGDVRDLASVKNAMHGVDYVFHAAALKQVPSCEFFPV
                     EAVKTNILGTENVLTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAMMEKIAVAKSRTV
                     NPEHTKICVTRYGNVLCSRGSVVPLWIEQIKQGNALTITEPSMTRFVMTLEEAVDLVL
                     FAFEEGKSGDILVQKAPACTIEVLAKAVSEIFASEQDIKIIGIRHGEKRYETLLTNEE
                     CANAIDLGDFYRVPSDNRNLNYDKYFKDGSTNRNLLTEFNSNNTDLMDVEQVKRKLLE
                     LDEIQTAIRDMVADEEM"
     misc_feature    17632..18486
                     /gene="fnlA"
                     /locus_tag="SCP46_0019"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.0018"
     misc_feature    17635..18306
                     /gene="fnlA"
                     /locus_tag="SCP46_0019"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 8.3e-09"
     misc_feature    17635..18483
                     /gene="fnlA"
                     /locus_tag="SCP46_0019"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 3.1e-162"
     misc_feature    17638..18273
                     /gene="fnlA"
                     /locus_tag="SCP46_0019"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 8.4e-09"
     misc_feature    18484..18627
                     /gene="fnlA"
                     /locus_tag="SCP46_0019"
                     /note="HMMPfam hit to PF08485, Polysaccharide biosynthesis
                     protein C, score 2e-23"
     gene            18766..19995
                     /gene="fnlB"
                     /locus_tag="SCP46_0020"
     CDS             18766..19995
                     /gene="fnlB"
                     /locus_tag="SCP46_0020"
                     /note="member of homology group 37"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlB"
                     /protein_id="CAI34621.1"
                     /db_xref="GOA:Q4JYL5"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYL5"
                     /translation="MIKNILITGAKGFVGKNLICTLEALKDGRDRTRPNLEIGEIFQY
                     DRDTDPILLDEYCKKADFVFHLAGVNRPQNPDEFMEGNYGFSSRLLEILDKYENTCPV
                     LLSSSTQASLEGRFSNSIYGQSKLAGEELFFEYGKKTGAPVLVYRFPNLYGKWCRPNY
                     NSAVATFCHNIAHDLPIQVNDPSVELELLYIDDLIQECLTALEGNPHRCNLDGLQILP
                     SPSGNYCYVPTTHRATLGEIVSLLETFKKQPNSLVMPEIPQGSFKKKLYSTYLSYLPV
                     DKFRFPLKMNIDERGSFTELLKTENTGQFSVNISKPGITKGQHWHHSKWEFFMVVSGR
                     ALIQERRIGLDENGQEYPILNFEVSGDKIEAIHMIPGYAHNIINLSDTENLITVMWAN
                     ESFDPRHPDTFFEQVEK"
     misc_feature    18778..19401
                     /gene="fnlB"
                     /locus_tag="SCP46_0020"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 2.9e-09"
     gene            19996..21180
                     /gene="fnlC"
                     /locus_tag="SCP46_0021"
     CDS             19996..21180
                     /gene="fnlC"
                     /locus_tag="SCP46_0021"
                     /note="member of homology group 38"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-L-fucosamine FnlC"
                     /protein_id="CAI34622.1"
                     /db_xref="GOA:Q4K1W9"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q4K1W9"
                     /translation="MKIKTDYSDIHFKDNGKLKLLIIVGTRPEIIRLSSVITKCRKYF
                     DVILAHTGQNYDYNLNGIFFDNLGLDTPDVYMDAVGDDLGATVGNIINTSYKLMNQIK
                     PDALLILGDTNSCLSAIAAKRLHIPIFHMEAGNRCKDECLPEETNRRIVDIISDVNLA
                     YSEHARKYLHECGLPKERTYVTGSPMAEVLHKNLSAIESSDIHERLGLKKGGYILLSA
                     HREENIDTDKNFISLFTAINQLAEKYNMPILYSCHPRSKKRLQESGFKLDKRVIQHEP
                     LGFHDYNCLQMNAFVVVSDSGTLPEESSFFTSQGYPFPAVCIRTSTERPESLDKAGFI
                     LAGIDENSLLQAVETAVSLAEDEDFGLPVPDYVEENVSTKVVKIIQSYTGIVDKIVWR
                     KS"
     misc_feature    20107..21135
                     /gene="fnlC"
                     /locus_tag="SCP46_0021"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 4.8e-105"
     gene            complement(21378..21464)
                     /gene="tnp"
                     /locus_tag="SCP46_0022"
                     /pseudo
     CDS             complement(21378..21464)
                     /gene="tnp"
                     /locus_tag="SCP46_0022"
                     /note="Lone member of homology group 0259"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase (fragment)"
     gene            complement(21546..22605)
                     /gene="tnp"
                     /locus_tag="SCP46_0023"
                     /pseudo
     CDS             complement(join(21546..21731,21877..22605))
                     /gene="tnp"
                     /locus_tag="SCP46_0023"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase (fragment)"
     gene            22686..22874
                     /gene="tnp"
                     /locus_tag="SCP46_0024"
                     /pseudo
     CDS             22686..22874
                     /gene="tnp"
                     /locus_tag="SCP46_0024"
                     /note="member of homology group 0047 7"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            complement(23086..23659)
                     /gene="tnp"
                     /locus_tag="SCP46_0025"
                     /pseudo
     CDS             complement(join(23086..23409,23390..23659))
                     /gene="tnp"
                     /locus_tag="SCP46_0025"
                     /note="member of homology group 31"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase"
     misc_feature    complement(order(23390..23394,23092..23409))
                     /gene="tnp"
                     /locus_tag="SCP46_0025"
                     /note="HMMPfam hit to PF05717, IS66 Orf2 like protein,
                     score 1.7e-52"
                     /pseudo
     gene            order(23726..24044,24061..24450)
                     /gene="tnp"
                     /locus_tag="SCP46_0026"
                     /pseudo
     CDS             join(23726..23923,23922..24044,24061..24450)
                     /gene="tnp"
                     /locus_tag="SCP46_0026"
                     /note="member of homology group 19"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1381 transposase"
     misc_feature    order(23973..24044,24061..24438)
                     /gene="tnp"
                     /locus_tag="SCP46_0026"
                     /note="HMMPfam hit to PF01609, Transposase DDE domain,
                     score 7.6e-14"
                     /pseudo
     gene            24711..>25070
                     /gene="aliA"
                     /locus_tag="SCP46_0027"
     CDS             24711..>25070
                     /gene="aliA"
                     /locus_tag="SCP46_0027"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34628.1"
                     /db_xref="GOA:Q4K2T2"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K2T2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    24711..24797
                     /gene="aliA"
                     /locus_tag="SCP46_0027"
                     /note="Signal peptide predicted for SPC2025 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    24957..25025
                     /gene="aliA"
                     /locus_tag="SCP46_0027"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     8038 a   3974 c   5050 g   8008 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact tgacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
      121 aatcttagtt ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcgtat aaaaacaagg gaggactgta taaaaggcag aaatcctttg
      241 ttttttataa ccaaggttta taaaccttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gacgaacata aagaagcgta tccttagtgc aggcctgact
      361 tttacatctg ctttgctttt agctgcttgc gaccaatcag gttcagatac aaaaacttac
      421 tcatcaacct ttagtggaaa tccaactaca tttaactatc tattagacta ttacgctgat
      481 aatatagtca attgaaacaa gaacaagaca aaagagcctc ataaaaggta ttgcaacttg
      541 gtaatacctt tttgaggtgc tttttgatat gagcccatgt tttctcaata ggattgtact
      601 caggtgagta gggaggaaga ggtaaaagtt tatgcccaaa ctcttcgcat aaaagttcta
      661 gcttccccat tctatggaat cttgcattat ccataataat aaccgatggt gtggttaatg
      721 ttggtaagag aaatttctga aaccaagctt caaaaaagtc gctcgtcatc gtctcttcgt
      781 aagtcattgg agcgattaac tcaccattca tttgttagac ctgcaatcaa agaaatcctc
      841 tgatatcttc ttccagatac tttacctctt attaactgac cttttaatga gcgaccatat
      901 tctcgataaa aataagtatc gaatcctgtt tcgtcaatct aaacaggtgc taggtgcttt
      961 aaactattaa aattcttaag aaataaggct actttttcta ggtcttgttc ataattagat
     1021 tgaaactaga atagtacacc tctgcttcta aaacattgtt agaaatcgat ttgactgtcc
     1081 tgatcgtttt gtcatgttct tatttcattt tactatattt ttggttcgcg ggaagtctac
     1141 taagatactt aaagatgcag atagtaaaaa aagatgtaga cattaccgta aaaaagtgat
     1201 ataattgtat gatgttcaag gtataggtgt taatcatgag tagacgtttt aaaaaatcac
     1261 gttcacagaa agtgaagcga agtgttaata tcgttttgct gactatttat ttattattag
     1321 tttgtttttt attgttctta atctttaagt ataatatctt tgcttttaga tatcttaatc
     1381 tagtggtaac tgtgttagtc ctactagttg ccttggtagg gctactcttg attatctata
     1441 aaaaggctga aaagtttact atttttctgt tggtgttctc tatccttgtc agctctgtgt
     1501 cgctctttgc agtacagcag tttgttggac tgaccaatcg tttaaatgcg acttctaatt
     1561 actcagaata ttcaatcagt gtcgctgttt tagcagatag tgagatcgaa aatgttacgc
     1621 aactgacgag tgtgacagca ccgactggga ctgataatga aaatattcaa aaactactag
     1681 ctgatatcaa gtcaagtcag aataccgatt tgacggtcaa ccagagttcg tcttacttgg
     1741 cagcttacaa gagtttgatt gcaggggaga ctaaggccat tgtcctaaat agtgtctttg
     1801 aaaatatcat cgagtcagag tatccagact acgcatcgaa gataaaaaag atttatacca
     1861 agggattcac taaaaaagta gaagctccta agacgtctaa gaatcagtct ttcaatatct
     1921 atgttagtgg aattgacacc tatggtccta ttagttcggt gtcgcgatca gatgtcaata
     1981 tcctgatgac tgtcaatcga gataccaaga aaatcctctt gaccacaacg ccgcgtgatg
     2041 cctatgtacc aatcgcagat ggtggaaata atcaaaaaga taaattaacc catgcgggca
     2101 tttatggagt tgattcgtcc attcacacct tagaaaatct ctatggagtg gatatcaatt
     2161 actatgtgcg attgaacttc acttctttct tgaaaatgat tgacttattg ggaggggtag
     2221 atgttcataa tgatcaagag ttttcagctc tacatgggaa gttccatttc ccagtaggga
     2281 atgtccatct agactctgag caggctctag gttttgtacg tgaacgctac tccctagcag
     2341 atggcgatcg tgaccgtggt cgcaaccaac aaaaggtgat tgtggctatc cttcaaaaat
     2401 taacgtcaac cgaagcactg aaaaattata gtacgatcat tgatagcttg caaaattcta
     2461 tccaaacaaa tatgccactt gagaccatga taaatttggt caatgctcag ttagaaagtg
     2521 gagggagtta taaagtaaat tctcaagatt taaaagggac aggtcggatg gatcttcctt
     2581 cttatgcaat gccagacagt aacctctatg tgatggaaat agatgatagt agtttagctg
     2641 tagttaaagc agctatacag gatgtgatgg agggtagatg agatgataga catccattcg
     2701 catatcgttt ttgatgtaga tgacggtccc aagtcaagag aggaaagcaa ggctctcttg
     2761 gtagaagcct acagacaggg ggtgcgaacc attgtctcta cctctcaccg tcgcaaggga
     2821 atgtttgaaa ctccggaaga gaagatagaa gaaaactttc ttcaggttcg ggaaatagct
     2881 aaggaagtgg cgagtgattt agtcatcgct tacggggctg aaatttacta cacaccagat
     2941 gttctggata agctagaaaa aaagcggatt ccgaccctca atgatagtcg ttatgccttg
     3001 atagagttta gtatgaacac tccttatcgc gatattcata gcgccttgag caagatcttg
     3061 atgttgggaa ttactccagt cattgcccac attgagcgct atgatgctct tgaaaataat
     3121 gaaaaacgcg ttcgagaatt gatcgatatg ggctgttaca cgcaagtaaa tagttcacat
     3181 gtcctcaaat ccaaactttt tggcgaacgt tataaattca tgaaaaaaag agctcagtat
     3241 tttttagagc aggatttggt ccatgccatt gcaagtgata tgcacaatct agacggcaga
     3301 cctcctcata tggcagaagc atatgacctt gttacccaaa aatacggaga agcgaaggct
     3361 caggaacttt ttatagacaa tcctcgaaaa attgtaatgg atcaactaat ttaggagaaa
     3421 tgatgaaaga acaaaacacg atagaaatcg atgtatttca attatttaaa accttgtgga
     3481 aacgcaagct aatgatttta ttagtggcac ttgtgacagg tgcgggggct tttgcatata
     3541 gcgcttttat tgttaagcca gaatatacga gtaccacgcg aatttacgta gtgaatcgcg
     3601 atcaaggaga caagtcgggg ctgacaaatc aggatttgca ggcaggaact tatctggtaa
     3661 aagactaccg tgagattatc ctttcgcaga atgtattgga aaaagtagcg acaaatttga
     3721 agttggatat accagccaaa acgttagcta gaaaagttca agtgactgta ccagttgaca
     3781 ctcgtatcgt ctcaatctct gtcaaggata aacagccaga ggaagccagt cgtatcgcta
     3841 attctctacg agaagttgct gcagaaaaga tcatcgctgt aacgcgagta tctgatgtaa
     3901 cgacacttga agaagcgcga ccagctacga ctccctcttc tccaaatgtt cgtctcaatt
     3961 ccttgtttgg tttttttgga ggagcagtcg taacagtaat tgctgttctt ttgattgagt
     4021 tgttcgacat ccgtgtgaaa cgtcctgaag atgtcgaaga tgtactgcaa attccacttt
     4081 taggggtcgt tccagatttg aacaaaatga aataggagga agttatgcca acattagaaa
     4141 tctcacaggc aaaattggat tttgtaaaaa aggcagagga aaattataac gctttgtgca
     4201 cgaacctaca gttaagtgga gatgatttga aagtattttc tatcacttct gtgaaacaag
     4261 gagaaggaaa atcaacgact tccaccaata ttgcttgggc ttttgcgcgt gcaggttaca
     4321 aaacgctgct gattgatgga gatattcgca attctgttat gttaggtgtc tttaaagcaa
     4381 gagataagat tacaggcctg acagaatttt tatcaggaac tacagaccta tcacaagggc
     4441 tttgtgatac caatatcgaa aatctctttg taattcaggc tggctctgtg tcaccgaatc
     4501 cgacagctct tcttcaaagt aagaatttca gtacaatgct tgaaaccttg cgtaaatatt
     4561 ttgactatat cattgtagat actgctcctg tcggtgtcgt gattgatgcg gctattatta
     4621 cgcaaaaatg cgatgcttct attttagtga cgaaggcagg tgaaataaat cgacgggata
     4681 ttcaaaaagc aaaagaacag ttggaacaca cagggaagcc gtttttggga gttgtgttga
     4741 ataaattcga tacttcagta gacaaatacg gttcttatgg aaattacgga aaaaaataag
     4801 tcgttaagta tttgtgtaag gacattttta gaactacaat caaaatcttt ggaattgctg
     4861 gcttcaaatc atattgattt gaaatgaaac ttgcaaaaga gttttttagg tgagtttctt
     4921 aatttgtgac tgaaatcaat cttctacttc cataccttgg aaaaataggg taaacgagaa
     4981 atgttttttc cataataaag ttttgatatg gctagtagag tagtaatata atagacttgt
     5041 tcggtaactg taaaaagtgt tatactattt ttatggaaac agtatacgac aaagcacaaa
     5101 aacttaactc aaaaaacttc aaactattga ttggtgtcaa aaaggaaacc tttcaactca
     5161 tgctagaaca cctgaattca gcctatcaga ttcagcaccg aaaaggtgga cgtccacgta
     5221 gtctgcccat ggaagaccag ctcattatgc ccctccgtta cttgcgatat tatcccactc
     5281 agcgtctgct ggcctttgat tttggcgtcg gtgtagctac ggtaaatgcc atcatcactt
     5341 gggtggagga tacacttcgt gcgtcaggta gctttgattt ggaccattta gaagccccga
     5401 gtgctgctgt ggctattgac gtgaccgaaa gtccgattca gcgtccaaaa aaaaccaaag
     5461 caaaaattat tctggtaaaa agaaacgaca caccttaaaa actcaaatta tgctggattt
     5521 gacgacacat aaagtctgtc aaatggcctt ttctgacgga catacgcatg attttactct
     5581 cttcaaagaa agtattggac aaagtttgcc tgaaacgacg cttgcctttg ttgacctagg
     5641 ttatttaggc atcttgaaat ttcatgagaa tactttcatt cctgctaaaa attccaaaaa
     5701 tcgccgcctg agtgaggatg ataagcagtt aaataaagag atgtcagcga tacgaattga
     5761 aattgaacat tttaacgcta aattcaagac cttccaaatc atgtcagtcc cttatcgtaa
     5821 ccgcagaaaa cgtttcgagt tacgggcgga attaatttgt gccatcatca attatgaagt
     5881 gaactagatt ccgaacaagt ctaatgaatt gtaatcatta gtgttcatac caagaaatat
     5941 caagtaccta tttttggaaa ttataaatgt tagatagtgt ttaaattttt acggagagat
     6001 tgttttgaga ggtaatttat gtatagggaa ataaaacgat taggtgatat tttactttct
     6061 ttcataggaa taatagtact gtttccagtg tttattataa ttgcaatcgc aataaagctt
     6121 gattcaaaag gtccagtaat atttaagcaa aagcgatttg gacttcataa gaaatcgttc
     6181 tatgtcttga agtttcgaac tatgaaggtt gaatcgccaa aatatgtggc gactcgagac
     6241 ttagataaac cagaacagtg gattaccaaa gtaggagctt gtttgcggaa aacatcttta
     6301 gatgaactgc ctcaactgtg gaacattctt gttggtgata tgagtgttgt aggacctagg
     6361 cctgtagcta taaatgaact tgatttgata aaagaaagag aacagtatgg tgccaatgat
     6421 atcttaccag gattaactgg atgggcacaa attaatggac gtgataattt gtcaacagag
     6481 atgaaggcag agatagatgg ttattatgta aaacatatgt cgttaagaat ggatcttaga
     6541 tgtatcctta gaacaatccc ctacgtatta aaacgtaagg gaattgtgga gggtagtggt
     6601 aagaaagagt tggagtgatg caatgaaaat tctatttgtt tgtcaacatt ataagccaga
     6661 accttttaga ttgtcagata tttgtgagga tctagttcaa agagggcacg aggtggctgt
     6721 tttgacaggg attcctaact atcccgaggg ggaaatatat gctgattatc gtaagagaaa
     6781 aaaaagaaga gagactataa atggtgttgc tatttttcgt tcatacacca ttgctaggag
     6841 gcaaaatact ttataccgta tattgaatta ttttagtttt gctctttctt ctacgatagg
     6901 tgttatattt gggcgttata aagcgaaaga tggctcagat tttgattgtg tctttgttaa
     6961 tcaactatct ccagttatga tggcttgggc tggtatagct tataagaaca agtacaataa
     7021 acctatgttt ttgtattgca tggatgtttg gccggatagt ttaattgtag gtggggtgaa
     7081 ggaaaatgga ttgatttaca agatatttga atttgtttca aaaaaagtat atcaagccag
     7141 cgattatata tttgttacta gtctatcttt taaagattat tttgtaaaaa aatttaatat
     7201 tcctctccac aaaattactt acttaccaca atatgcagag gatttatttg taccaaatga
     7261 attaaaaacg aacaaaaata ctattgactt aacttttgct ggaaatattg gaaaagctca
     7321 gaatttagag actattttga aagcagccag tgcaatagaa cagattcccg atttagcaaa
     7381 gagagttcat tttcattttg ttggagatgg tacggaacta ttaaacatgc aaaaattagc
     7441 atgtgaacta gaattagaga acacttcatt ttatggtaga cgtccattag aagagatgcc
     7501 ggatttttat acaaaatcag atgcgatgct agtttcttta ataggcgact ctataatttc
     7561 tcgcacctta ccaggtaagg tacaatctta tatggcggca ggaaaaccaa ttataggagc
     7621 gatttcagga gatactcaga gagttgtaaa agaagcaaaa tgtggtttca taagtccgga
     7681 agggaatgtt gatcagttag tgagaaatat tcgtaagttc tgtttgcttt ctgtagagga
     7741 aagagagaaa ctaggaaggc aagctcgttg ttgttatgaa gaacagtttt cgaaagagtg
     7801 gtttatgaca tacttagaaa atcatttaaa agaggggttt ctatcatgaa ggttttaatg
     7861 attaattccg tttgtggtat taggagcact gggagaattt gtacggatct cgcaactgct
     7921 ttgacagaag aaggatatga ggttaaaatc gcctatggtc gtgagtatgt tccgaaacaa
     7981 tttcaacagt atgcagtgaa aattggtaca aagtctgata ttcgttttca tgcgattcgt
     8041 tctcgattat ttgacgaatc tggctttgga agtagacagg caactgttaa ttttattaaa
     8101 tggataaaag agtttgaccc tgatgttatt catcttcata atcttcatgg atattatatc
     8161 aatattgaac tgttatttga ttatctccgt atatgcggta aaaagattat atggactttg
     8221 catgattgtt gggcatttac aggacactcg gctcactttg attgtttgga atgtgagtca
     8281 aagggggttt gtgaccatcc atctcagaaa aatgattatc ctaagtcgtt cgtgaatttt
     8341 tcaaggcgaa attatcaaag gaagaaaaaa tgttttacac atattcctaa tctcactatt
     8401 gttactcctt cgcaatggct agctaacttg gtaggacagt catttttaaa agaatatcca
     8461 gtgaaagtaa ttcataatgg cattgatact actgtctttc aaccgaggct aatagccgct
     8521 caaaagttga aaaaaagata ccatcttgaa ggaaagcagg tattgcttgg tgtggctgct
     8581 atctggactg ataaaaaggg attttctgat atgttagtcc ttgcgagtca tctagctgat
     8641 aatcagagaa tagttttgat agggttaaaa gataggcaac tcaaaaaatt acccaaaggt
     8701 attattgggc taacagagac taatagtcca gaagagttgg cagcatggta tacactagcg
     8761 gatgtattct taaatcctac ttatcaagat agttacccga caactaattt agaagctatt
     8821 tcttgtggga caccagttat cagctatccg acaggtggta gtgtagaaag tgctaaactt
     8881 tatggtctcg tttgtcagga tagaaacgta gcttctattt tatcttcgtt agaaaaagtc
     8941 tctcagctat ctaaaacaga aaaattagat ttttcaattg caagttttat taaacaaatg
     9001 aaatatttat actagaactt gaattatagg aaaatgagga atttgcatta aaatgatgaa
     9061 aagaatttat tatcaccttt tggctatttt ggcttggact cttccaaatt cttatgcttt
     9121 tattgattcg ttaaaggtgt tttttccgaa tattagttta caaattgcag gttctctttt
     9181 ggctgttatc tcgataggaa tttttatcac tagaatatat tatacaggat acgaagtttt
     9241 tatatctcta ttggtttgta tttttatttt aattttttat tcaactcgct ttttttattc
     9301 gactaatgta gagttgtatc attctttctt caattccttt ctgattcgtc cagttcctgg
     9361 gatattagta gcgatgctgt tagctaagaa taatcatata aaaggtttca taaaatggtc
     9421 agaacctatg atgcttttct atacattgac atcattttta gcagccctat ctcctagaaa
     9481 tagcattatt atttaccaat ctttatctta ttatgccatg acagcttata tgattaatgt
     9541 gtttaatatt atatacaaag agaaaatatt ggaggagcaa ctgacgtatt tcagattctc
     9601 agcgtggaat tttattagat attttttact tttgattcaa gcttttaatg cactctcagg
     9661 aggtgggaga ggtgccttta tcttattaat tatttttaca ggaatattat taataagaat
     9721 tgctatgaat tttaagttcc ttttctcatt cattggaggc ttatctgcta tagctctagt
     9781 tgttttttgt ataaaagatt tggatttcac atggctcttg aatatggacg gtggagagcg
     9841 attgttgaac ttcttcggca gacctgaacg tatatctaca gataatagac tattgattta
     9901 tgatactgtt tggtctgcaa tacaggaaaa acccttttta ggatggggag ttggttcaac
     9961 ttttttaaaa tttaatggat attcacataa tattgtattg gatttattgc atgatatggg
    10021 aagttttggt ttattaatta ttctttcggc tttctttgct tcttcagtaa tattgtacaa
    10081 attacgtaaa atagattgga aagtgaattt atttattctg atgtttctag aagtatatgt
    10141 tcacatgagt ttcagtggaa gctatcttgc agatggtaga ctatggtttt tggtgatctt
    10201 tacttattgt tactacaggt ggaaagtgca ggaaaaggat gaagttagca attttattat
    10261 ctgatatttc aaaaatagga ggagtgcagc gtgtcacgac agctcttgtt aatgaacttt
    10321 gtcaaaatat agacgttaca attatcagca tcttttcgga aaatgagcta ccagcttttg
    10381 gactttcaga tagagttcag gtgagctatc ttttgaaaga acatgttaat ttgaagaaga
    10441 atttttttaa agttagtgga gctttgcgaa aagtgttgaa aaaacagcag tttgatgttg
    10501 ttctatcgtc aggaactggt ctagtatcct ttctttggtt tgctagtttg ggaattccta
    10561 ccagactttt ggcatgggaa catcagtgtt tttactttgg gagatcgttt ggtctagagt
    10621 ggttggggcg aaagctagcc tgtcgttttg ctgagagtat tgttgtcttg actaaaaaag
    10681 atgaaggatt ttacaaagag aatcgtccta aggctcatat tgaacaaatc tataatatcc
    10741 tagacatgga ttcacaaaca gctaagtgtc agctctcttc taaaaaaatt atcagtgttg
    10801 gctctttagg acgacaaaaa ggttttgatc tggctcttga ggtagctagt caaatacaat
    10861 taagctatcc agattggcag tgggacattt atggtgatgg ccccgataga gaaaaattag
    10921 aggagaaagt cagggaatac caattagaag gctttataaa tttgaaaggg cttgttcaga
    10981 atgttcggga gctctatcct gactactcta tctacgccat gacatcacga catgaaggat
    11041 taccaactgt attattagaa gctaaaaact gccagatgcc tgttatttca tttgattgta
    11101 actgtggacc ctctgatatt atttcagatg gaagaaatgg ttttttgatt gattgttttg
    11161 atgtaaatat ctatgcaaaa actttatcta aattaatgac tagtttagag ttgcgagaac
    11221 aagttgcaaa atcgagtgtt attccagcag aagaattgtc aacaacttat atcctagata
    11281 agtggaacaa tctattaaag atagaaagaa gataatatga aaatagtcca tgtagaagat
    11341 ttttttcatc cagatgcagg ttaccagatt aatgttttac caaaatatct agcaaagttt
    11401 ggtcatgaac aggtgattat cacttcagaa atggataaaa tccccgataa tcttacccaa
    11461 ttttttggac gagaaaatat agaagagaga gatagaagtt acgaagagaa gcatcatgtg
    11521 aagattattc gcttacctct tcatggattt gtaagtggac gtgcgatttt ttctggaaag
    11581 cttatttcgg ctattaaggg tctttctcca gaggtattgt atattcatgg gaatgacacc
    11641 ttaacaggga ttcgtctcct tttagctcga aagaaactta attgcagaat cgccaccgat
    11701 agtcatatgc ttgaaatggc atcaagaaat cctttcaaca actactttag gagattttat
    11761 aaaaccttga ttactcccat tttgataaaa gaacagatac caattattcg gacgcaagat
    11821 gataattatg ttgaaaaaca cttgggaatt cctttatcgc aagctccatg gatttcttat
    11881 gggtcggata cagcgttctt tcacgcagat agccagatta aggaagattt tcgttctcaa
    11941 tatcaaatcc cttcagatgc tcttatttgt gtttacgcag gaaagttaga tgagcataag
    12001 ggtgggatgt ttttagcaga gtctctaagt aaaaagttaa atacggagca accaattgtt
    12061 ttcattatag tgggtaatac aaatggagag tatggagaag ctgtcgagaa aagtttctcc
    12121 caatctgaaa accaaatctt gcgctttccg actcaaaaat atcaaaaatt agcacagttt
    12181 tttcaggtag cagattttgc tttatttcct aaacaatgta gtttaagttt ttatgatgca
    12241 caggcctgtg gtttaccagt tttattggaa gataataata tcaacctcga tagaacttct
    12301 cattataatg gttggacgtt caaggctaac agcaaattaa gtttgagaga ttcattaaaa
    12361 atgattgcga gtctagataa agagaagaga caagagtact ctcagaatgc actgcactat
    12421 atccttgaac attataatta tgaagataaa gcaagagaat atgaaaagat tcttataggg
    12481 gaacgtacga aatgagatag ttaatatttc gttattttat aggaaaggtg gatttaatga
    12541 aaatttgcat tgtttcagtc ggagtgagcg gactaccgat tccagctgta aaagggggag
    12601 cagtagaaaa tctcattgat aattatttaa gttacaatga gaaatataat catgatgaaa
    12661 ttacggtcgt tagttgtgac cataaggagg cgcgtgaggc ttcaaaaaaa tacaagtatg
    12721 cccaatttgt ctatatagat attcattcac ttaaatataa aataaacaaa acaatacgtt
    12781 ataccatcaa taaatattca cctttcttcg tagggaacgc ttatatcagt caattgccag
    12841 acttgtctgg ttttgataca gttttgattg aaaatcgccc tgaatacggt tattatattc
    12901 gtaaaaagtt taaaggaaat cttgttttac atcttcacaa tgatttatta atggacaatg
    12961 agtattctgt agattatagc gtttatgata aaattatcac agtatctgac tatattagga
    13021 ataggtcaga agtagtaacg tcaggtgttc cgatacagac tgtctataat ggtattgaca
    13081 cagaactttt tttgcagaat ttctctgaag ttgatttatc agatcttaaa aatcagttgg
    13141 aaattttgtc ggatgatttt gtgattgttt tttttggacg tatcaacaaa aataaaggta
    13201 tcaaagaact gcttgaagcc ttcttgttgc taccaaagaa tttgaatata aaattactag
    13261 ctgttggtag ttctatattt ggtcagacgg agttggatac tttcacaaca gagctacggc
    13321 aattggcaaa acaagcatca gataaagttg tttttacagg ctatgttaat tacaaagaca
    13381 ttcctaagta tcatcatatt gcagattgca ttgttattcc atctatttgg gaggaaccag
    13441 cgagtttgac ggtctgtgaa gctttgatat cagggaaata tgttattaca acagatactg
    13501 gagggacacc agagcttgta gctggcagtg atgcccttgt ggtagcaaat gatgagtgta
    13561 tagttgaaca cctcaaaaca gccctattga gtgtctacca aaaagggaaa tgctcttcgg
    13621 ttattacttc taatagagat agaggagcct atttttctat tgaaaaatat ggaagaaact
    13681 tacgaaaaga gctcacacaa aatgaaagaa ttattaacat atgagtcgtg taaaaaatag
    13741 tttttttaat attttagctg gaatagttgg tactatcata tcgagtgttt tagctttcat
    13801 agttagaaca gtgtttatcc gagttttggg agagacttat ctaggtttca atggtctata
    13861 caccaatatc ttaacagttt tatccctaac tgaattaggg atcggatcat caattgctta
    13921 tttgatgtac aaacctttag cagaaaaaga tggggacaaa ttagctcaag tagttcaatt
    13981 ctataaaaaa atatatcgag tgattggtat cattattctt attttaggtt tgtgtctcgt
    14041 tcctttttta ccagtcattg taaatttaaa aaatgcagaa gatttgaact atacagcatt
    14101 gtatttgctt tatttagcag atacagtttc tacttatcta ttctttgcat ataaaagagg
    14161 ggtattggct gctgatcaaa agatctatgt tgcgaatatc tttgatataa ttataacgac
    14221 aattttatct attttccaaa ttatcacttt gatgattttt aaagactttt atctatatat
    14281 tattttaaaa attgctaaaa atcttacttt gaacctagta attagtttaa aagtagataa
    14341 aatgtatcca agtattcata aatttaaagg gatagctccg cttccaaaaa tggaaagacg
    14401 actagtttgg aaaaatgtat atgctacctc tgttcgacaa atctttaacg aattaatgaa
    14461 ttcaacagat agtatagtta tttccattgt cttaggaata gttatggttg gtaagtattc
    14521 gaactatgct tatattttat caatcgtata tattttcttt ggaggaattt ttaatccgat
    14581 tcaggcttct attggaaacc tatctctgtc agcttctata gagaaaaaaa atgaaatctt
    14641 caatagatta cgttttataa attttttctt tttatcattt tgctcaagtt gtcttctagt
    14701 attggtaaat ccttttatca ctatttggat tggagaaaat tacactttat catttacagg
    14761 tgtgattgca atagttggta tgttattcgt tagacaaact ggaaattgta caaccatttt
    14821 tcgtttggga gaaggatatt ttagagatta tcatttttct cctttaatcg cgggcatttt
    14881 aaatttagtt gtttcagtaa ttttagtgaa ttatataggt attgcaggtg tttttgttgg
    14941 aacaatgtta ggatttggtt tccaatttat actggtggat acaattgtta cttataaaaa
    15001 agtacttagt cgtccactat cagagtttta tttaagatgg ttgcagacga tcttattaac
    15061 tgtaggttta tgtattgcga gttactattt atctcgattg gttagagtga atagtatata
    15121 tgatttgata ctgttgtttg tagtggttat tggatttaat ttttttgctt tatgttttat
    15181 ttattggcga aatgatgatt ttcaatattt tattcaattg gttaaaaatt ttatgaaaaa
    15241 tttggaggaa aaaaatcatg attaatgtaa tcggattagg ttatattgga ttgccaacaa
    15301 ttttaatgtt ggcaacaaac ggcgtgaaag tagttggaac tgactacaat caggatttgg
    15361 tgagaacttt aaatgaaggt caaacaacct ttaaagaaga tggattggat gaactatttc
    15421 ataaagcagt ggagtcgggt gtggacttta caaccgaata tcaacaaacg gatacctata
    15481 ttatttccgt tccaacacca tatgactcct tctctaaaaa aattgatcca agctatgtga
    15541 ttgaagctac gaaaacggta cttgataatt gcaataaagg agcggttatt attattgaat
    15601 cgaccgtatc accaggaacg gttgataaat ttattcgacc tgttgtagaa gaaaaaggtt
    15661 ttgttattgg tagtgatatt catcttgtcc atgctccaga acgtattatt ccagggaata
    15721 tggtctatga attggtgaat aataaccgta caattggagc tgatgaccta gaaatcggct
    15781 ataaagtgaa agagctttat gcttcatttt gtaagggcga tattgttgtt acagatatta
    15841 gaactgcgga gatgaccaag gtagtagaaa atacatttag agctgtaaat attgctttcg
    15901 ctaacgaatt agcacagatc tgtagttatg ataatatgaa tgtttatgaa attatccgga
    15961 tctgtaatat gcacccacgg gtaaatattc tacaacctgg acctggtgtt ggtgggcatt
    16021 gtatttctgt ggatccttgg ttcttagttg gagattatcc tgagttgaca aatgttattg
    16081 aacattctat gcgaacaaat gctgccatgc cagaatttgt attaaatcgt atctatacca
    16141 ttatgaacga acatcatcta acagatatta gtcgggttgg tctatatggt cttacctaca
    16201 aagagaatgt agatgatatg cgtgaatctc caacgcttca gttattagaa tctatgagcc
    16261 gccatctggc aacacctgct attaaagtat atgatccatt tatagaaaaa gatgttgtgg
    16321 cgaatcagtc acatgattta gatgaatttt tatctaatgt tgatattgtt gtactgttgg
    16381 ttggtcatga tgagatttta caaaatatgg ataaactaaa agataagata gtgttagata
    16441 cacgttatat ctgtcatctt gatggaactt acagattata attagtgata aataaagtaa
    16501 ggattgacta tgaaaaaaat agttgtaatt ttcggaactc gtcccgaagc tatcaagatg
    16561 tgtcccttgg ttaaagagct aagaacacgt gagaatcttg aaacattggt ctgtgttacg
    16621 ggtcaacatc gtcaaatgct ggatcaagtt ttggatactt ttaggattac gcctgatttt
    16681 gatttatcta ttatgaagga caaacaaact ctctttgatg tcacaattgg cattttggaa
    16741 ggcatgaaga ctgtcttaga gtcagttaat cctgatttaa tattagttca tggggatacg
    16801 agtacaacat ttgccagttc actggccgcc ttttatctac agattccaat tggacatgta
    16861 gaggctggtt tgcgtactta tgatatttat tcaccttatc ctgaagaatt taatcgtcaa
    16921 gcagtaggtg ctttggctca gtatcatttt acaccaacac aactctcaaa agacaatctc
    16981 ttgagagaag gaaaaaattc tgaagctata tttatcacag gtaacacagc aattgatgct
    17041 ttacaaacta caattcaaga ggattatact catcctgagt taaattgggt tggggatagc
    17101 aaactaatat taattactgc tcatcgtcgt gaaaatattg gtgacccgat gaggcacatg
    17161 tttagagcaa tccgacgtat cattgaagaa cattcggata taaaggctct ttaccccatt
    17221 catatgaatc ctctagttcg tcagattgct gaggaagaac taagcggatg tgaacgtatc
    17281 aaaatgatcg atccgttgga agtattagat tttcataact ttttatcacg gagttatctc
    17341 attttaacag atagtggtgg tatccaagaa gaggcaccta gtttaggaaa acctgtttta
    17401 gttatgagag atacaactga acgtccggag ggaattaaag caggaacttt gaagcttgta
    17461 ggtactgatg aggacaatat ttatagacat tttaaagaat tgttagaaaa tgatttagtt
    17521 tatcaagcga tgagccaagc ttcaaatccg tatggagatg gaacagcttg caagaaaatt
    17581 gcagacatac tagaaggaga agtataatat atgtcacaat ttacaggaaa aactctccta
    17641 attacaggag gaacaggttc atttggtaat gctgtcctta atcgtttttt acagactgat
    17701 attggtgaaa ttcgtatttt ttcccgtgat gaaaaaaaac aggatgatat gcgtcatgag
    17761 tttcaggtaa aagtaccaga agtagctggg aaaatccgtt tttaccttgg agatgtgcgt
    17821 gacttagctt cggtaaaaaa tgctatgcat ggtgtggatt atgtttttca tgctgctgct
    17881 cttaaacaag taccttcgtg tgaatttttc cctgtagaag cggtaaaaac taacattttg
    17941 ggaacggaga atgtcctcac tgcggctatc gaagctggtg taaagcaagt tatctgtctt
    18001 tctacagata aggcggctta tcctgtcaat gctatgggaa catccaaggc tatgatggaa
    18061 aagattgctg ttgctaagtc caggacggta aatcctgagc atacaaagat atgtgtgact
    18121 cgctatggga atgttctgtg tagccgtgga tctgtcgttc ctctttggat tgagcaaatt
    18181 aagcaaggaa atgctcttac aattactgaa cctagcatga cacgttttgt gatgacatta
    18241 gaagaagcag tagacttggt tttatttgca tttgaagaag ggaaatctgg agatatacta
    18301 gttcagaaag caccagcatg tacgattgaa gtgttggcta aggctgtatc agaaattttt
    18361 gcctcagaac aagatattaa gattataggt attagacacg gagaaaaaag gtatgaaaca
    18421 ctattaacta atgaagagtg cgcaaatgca attgatttgg gtgattttta tagagttcct
    18481 agtgataatc gtaatcttaa ctatgataag tatttcaaag atggtagtac gaatagaaat
    18541 ttgttgacag aattcaatag taataatacc gatttgatgg atgtagagca agttaaaaga
    18601 aagttgctag aattagatga aatacagaca gcaattcgtg atatggtagc agatgaagag
    18661 atgtaaaatc ttttaagata cattaaaatt atcaaggata tataatgtat catgtattgt
    18721 cgagagagtt gactattaaa acagcatata aaacaaggag ggggcatgat taaaaatatt
    18781 ttaatcacag gagcgaaagg atttgtagga aaaaatctta tctgtactct ggaagctttg
    18841 aaagatggac gagataggac tcgtcctaat ttagagattg gagagatttt tcagtatgat
    18901 cgtgatacag atccgatttt attagatgaa tattgtaaga aggccgattt cgtattccat
    18961 ttagctggtg tcaatcgtcc acagaatcct gatgaattca tggagggaaa ttacggtttt
    19021 tcaagtagat tattggagat tttagacaag tatgaaaaca cttgtcctgt tctactctca
    19081 agttctactc aagctagttt agaaggccga ttttcaaact ctatatatgg acaatctaag
    19141 ctagcagggg aagaactctt ctttgaatat ggaaagaaaa cgggagcacc tgtcttagtt
    19201 taccgtttcc cgaatcttta tgggaagtgg tgccgtccta actacaattc tgctgtagca
    19261 actttctgtc ataatatagc tcacgattta cctattcaag taaatgatcc aagtgtagaa
    19321 ttggagttgc tgtatattga tgatttgata caagagtgtc taactgcatt ggaaggaaat
    19381 cctcatcgtt gtaatctaga tggattacaa atcttaccta gcccatcagg aaactactgc
    19441 tacgtaccaa cgactcatcg tgcaacctta ggagagattg tctctctatt agaaacattt
    19501 aaaaaacagc ctaatagttt agttatgcct gaaattcctc aaggatcgtt taaaaagaaa
    19561 ttgtattcta cctacctatc ttatttacca gtagataagt ttaggtttcc tctaaaaatg
    19621 aatatagatg aacgaggtag ttttacggaa ttattaaaaa cagaaaatac gggtcaattt
    19681 tctgttaata tttctaaacc tggcattacc aaagggcaac attggcatca ttctaagtgg
    19741 gaatttttca tggttgtttc tggtcgtgct ttaatacaag agcgtaggat agggctggat
    19801 gaaaacggtc aagagtatcc tattctgaac tttgaagtgt cgggcgataa gattgaagca
    19861 atacatatga taccgggcta tgcacataat attattaatc tttctgatac agaaaatcta
    19921 attactgtca tgtgggctaa tgagtcattt gatcctagac atccagatac tttttttgaa
    19981 caagtggaga aataaatgaa aattaagaca gattatagtg atattcattt taaagataat
    20041 ggcaaactta agttattgat tattgtggga acacgtccag agattatacg tctaagtagt
    20101 gttatcacta aatgtcgaaa gtattttgat gttattttgg cacatactgg acaaaactat
    20161 gattacaatt taaatggtat tttctttgat aatttagggt tagacactcc ggacgtatac
    20221 atggatgctg ttggagatga tcttggtgct actgtaggga atattattaa tacttcatac
    20281 aaattgatga atcaaattaa accagatgct ttattgattt taggggatac aaattcttgt
    20341 ttatcagcta ttgctgccaa gcgtttacat attccaattt ttcatatgga ggctggcaat
    20401 cgctgtaaag atgagtgcct gccggaagag actaatcgtc ggattgttga tattatttca
    20461 gatgttaact tagcatactc tgaacatgca cgtaagtatt tacatgagtg tggtttacct
    20521 aaagagcgca catatgtaac tggttctcct atggcagaag tgctacataa aaatttatct
    20581 gccattgagt cttcagatat ccatgaacgt ttgggattga aaaaaggagg ttatatctta
    20641 ctttcagctc accgtgagga aaatattgat acagataaaa attttatttc tctctttaca
    20701 gcaattaatc aattagctga aaagtataat atgccaatct tatattcttg ccatcctaga
    20761 tcaaagaaaa ggctacaaga gagcggtttt aaactagata aacgtgtgat tcagcatgag
    20821 ccactaggat tccatgacta taattgttta cagatgaatg catttgttgt agtatctgat
    20881 tcgggaactt taccggaaga aagtagtttc tttactagtc aaggttatcc ttttcccgct
    20941 gtatgtattc gtacaagtac agaacgtcct gagtccttag ataaggcagg atttattttg
    21001 gcaggcattg atgaaaattc tcttcttcaa gcagttgaaa ctgctgttag cttggcagaa
    21061 gatgaggatt ttggattacc ggttccagat tatgttgagg aaaatgtctc tactaaagtt
    21121 gttaagataa tacagagcta tacagggata gtggataaaa tagtttggag gaaaagctga
    21181 attgtatatt tttaataaat caaaacgaga tgattaattc ttagtagaac aagagtaaaa
    21241 ttgaacgtat ttgatggaaa tgtcttactt gatagtcgag ggatagccat tctatcggat
    21301 ttttggcttg tttttgcgct tcatgtttga tagaataaag ggctctttgt caactgtagt
    21361 gggttgaaga aaagctaagc ttgagaaagg acaaatttcg tcctttcttt tttgatgttc
    21421 agagcgataa aaatccgttt tttgaagttt tcaaagtttc gaaagtaacc gcccaataac
    21481 gaagtatatt gaaaaatctc cagactagag aactcacgga tagttcctaa tctggagatt
    21541 tcttatttgc acttttcttg tacaacttta gtccatggta aataagcctc taaaacctct
    21601 ttgtttacga gagtttcctc gtttggaaga cattctagaa gataggatag atatttctcg
    21661 ctatttataa tggattgaaa taagatatga acaaatcgat taggaaagga aaattgattt
    21721 atagaaatgt tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga
    21781 cgtttagctg tttccaacaa gctcataata atagctcttg ctttagctcc ttcaaaactt
    21841 tgagaaaata accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac
    21901 tcttttactc cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag
    21961 gaccagatgt ccgtctttca aaatagtctt aaaggtttct tcatacttga ggctgtattc
    22021 aattgccctt cctagttttg aacctgctaa aactgactga cggcggcacc aagcaaagaa
    22081 gtcttccatt aggggctgga gatgttcttg acgtttctgt agtcgttcat cagctggcaa
    22141 agcctcccag tctctttcca aggaaaataa ctgatcacaa taggctaaac ctttagctcc
    22201 taaggatgat ttatctgctt gcttgggggt cgcttcaaaa aacttccttc tcacatgtgc
    22261 ccaacatcca acaagtgcag cttcttccag ttgacgataa gcttctagcg gttcgcagtt
    22321 taccaagctt agcgtcgcct tgctcctaaa ccttggactg ctatcgcata ggcagaacta
    22381 gaggactaaa gtcctaagtt actgccgcaa catgtcacaa tgaacatagc cagaataatc
    22441 tcctaggaat tcttgtacta ctaaaccact ccgacgctga tcatggtggt acagcgtgat
    22501 tgcttgattc tcagctttcc cagacaaaaa ggtccaatag taagtcagct gactatcact
    22561 ctctagcacc ctataagaag tttcatctgc atgaagtaag ggcttgagtc aatagtctcg
    22621 ttataaaggg gctttaggaa taggagcttt cacaagctta tccagatgat tatcttttac
    22681 tcgttatgga caatgctata tggcataaat caagtacctt aaagattccg actaatattg
    22741 gttttacctt tattcctcca tacacaccag agatgaaccc cattgaacaa gtgtggaaag
    22801 agattcgtaa acgtggattt aagaataaag cctttcgaac tttggaagat gtcatacaag
    22861 gactggagaa ggaggtgata aagtccatcg ttaatcggag atggactaga atgctttttg
    22921 aaagcagatg agtataaaaa gaaagtcctc atttcaatag aaatcacgac tttctgatgg
    22981 atttatagta aaatgaaata agaacaggac aaatcgatca ggacagtcaa atcgatttct
    23041 aacaatgttt tagaagcaga tgtgtactat tctagtttca atctactata tttttggagt
    23101 gatagaaaag cccttcatca gccaatctac ttgttcaggt gcgagagctt tgacatcctt
    23161 ttctgtactg ggccaagtca gtctgccgtt ctcaaagcgt ttatatagta gccaaaatcc
    23221 ttgaccatcc cagtaaaggg ctttaaagcg gtctttacgt ccaccacaaa agagaaaaac
    23281 ttgacctgag aaaggatcta attcaaagtg ggttttaacc agataagcca gtgaatcaat
    23341 gccttgcctc atatccgttt tcccacatac gagatagacc tgccctaggc tagatagatg
    23401 aattgtcata gagcaacacc ttatccaaaa gctgttctat catttcgaga ttgagagatt
    23461 gaaaaaaact tacttcaagc ttgccaatac gaattttaag cagaatatca tttctctttt
    23521 tagaatcaaa aggacgagat tgtggaatct ctacaggaac aataggttgt ggcattaaaa
    23581 tatcctccaa tagttttact ttactaatag tatacaggag gagctccatg aatgatagat
    23641 accttgttat gacgcgctta ctaaacaact aactgatgca cgatttaagc gccttgttgg
    23701 tgttcagcgc acgacttttg aagagatatt agctgtatta aaaacagctt atcaacttaa
    23761 acacgcaaaa ggtggacgaa aacctaaatt aagcctagaa gaccttctta tggccactct
    23821 tcaatatatg cgagaatatc gcacttatga acaaattgcg gctgattttg gtatccacga
    23881 aagcaactta ctccgtcgga gccaatgggt tgaagtaact cttgttcaaa ggtggtgtta
    23941 cgatttcaag aactcctctc agttctgagg acacggtaat gattgatgcg acggaagtac
    24001 aaatcaatcg ccctaaaaaa acaattagcg aatcattctg gtaaaaagaa atttcacgct
    24061 atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctttgga tatcgctgtg
    24121 aactatagtc atgatatgaa gttgttcaaa atgagttgca gaaatatcgg acaagctggt
    24181 aaaatcttgg ccgacagtgg ttatcaaggg ctcatgaaga tatatcctca agcacaaact
    24241 ccacgtaaat ccagcaaact caagccgcta atagctgaag ataaagcctg taaccatgcg
    24301 ctatctaagg agagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaatg
    24361 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct
    24421 ggtattatca atcatgaact aggattctag ttttgcagga agtctattga aggatctttt
    24481 gctttagttc cttggtcaag gttgattatt ttcacggagc gcttccgatt gttttcataa
    24541 accatttgcg catagtcagc agaataaatc tttttgaaac gtccctttcc tagacattat
    24601 agaactttca gattcatctg aatttaccaa atcaacacaa aaattctgaa aattctgttg
    24661 acatctttct gaaaagagtc tataatggag agaaagtttt aaaggagaaa atgatgaaaa
    24721 gttcaaaact atttgccctt gcgggcgtga cattattggc ggcgactact ttagctgcat
    24781 gctctggatc aggttcaagc actaaaggtg agaagacatt ctcatacatt tatgagacag
    24841 accctgataa cctcaactat ttgacaactg ctaaggctgc gacagcaaat attaccagta
    24901 acgtggttga tggtttgcta gaaaatgatc gctacgggaa ctttgtgccg tctatggctg
    24961 aggattggtc tgtatccaag gatggattga cttacactta tactatacgt aaggatgcaa
    25021 aatggtatac ttctgaaggt gaagaatacg cggcagtcaa agctcaagac
//
