LOCUS       CR931722               22062 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 656/63 (serotype 48).
ACCESSION   CR931722
VERSION     CR931722.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22062)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 22062)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..22062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="656/63"
                     /db_xref="taxon:1313"
     gene            <1..163
                     /gene="dexB"
                     /locus_tag="SPC48_0001"
     CDS             <1..163
                     /gene="dexB"
                     /locus_tag="SPC48_0001"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="CAI34666.1"
                     /db_xref="GOA:Q4K2R1"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="UniProtKB/TrEMBL:Q4K2R1"
                     /translation="DRRFLVVANLSNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVP
                     WDAFCVELL"
     gene            322..378
                     /gene="aliB"
                     /locus_tag="SPC48_0002"
                     /pseudo
     CDS             322..378
                     /gene="aliB"
                     /locus_tag="SPC48_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(349..840,842..1168))
                     /gene="tnp"
                     /locus_tag="SPC48_0003"
                     /pseudo
     CDS             complement(join(349..840,842..1168))
                     /gene="tnp"
                     /locus_tag="SPC48_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(778..840,842..1150))
                     /gene="tnp"
                     /locus_tag="SPC48_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 3.8e-23"
                     /pseudo
     gene            1402..2847
                     /gene="wzg"
                     /locus_tag="SPC48_0004"
     CDS             1402..2847
                     /gene="wzg"
                     /locus_tag="SPC48_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI34669.1"
                     /db_xref="GOA:Q4JYH8"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH8"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLGFSILVSSASLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIGNVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KMSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1402..1518
                     /gene="wzg"
                     /locus_tag="SPC48_0004"
                     /note="Signal peptide predicted for SPC2066 by SignalP 2.0
                     HMM (Signal peptide probability 0.999) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1606..1953
                     /gene="wzg"
                     /locus_tag="SPC48_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 2.9e-61"
     misc_feature    2131..2574
                     /gene="wzg"
                     /locus_tag="SPC48_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 8.4e-70"
     gene            2849..3580
                     /gene="wzh"
                     /locus_tag="SPC48_0005"
     CDS             2849..3580
                     /gene="wzh"
                     /locus_tag="SPC48_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI34670.1"
                     /db_xref="GOA:Q4JYH7"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH7"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGIRMIVSTSHRR
                     KGLFETPEEKIATNFIKVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDTIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     misc_feature    2852..3460
                     /gene="wzh"
                     /locus_tag="SPC48_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 2.6e-37"
     gene            3589..4281
                     /gene="wzd"
                     /locus_tag="SPC48_0006"
     CDS             3589..4281
                     /gene="wzd"
                     /locus_tag="SPC48_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI34671.1"
                     /db_xref="GOA:Q4JYH6"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH6"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSISVNDRVSEEASRIANSLREVAGQKIISITRVSDVT
                     TLEEARPTISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTRVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     misc_feature    3607..4023
                     /gene="wzd"
                     /locus_tag="SPC48_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 9.3e-52"
     misc_feature    4129..4206
                     /gene="wzd"
                     /locus_tag="SPC48_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4291..4974
                     /gene="wze"
                     /locus_tag="SPC48_0007"
     CDS             4291..4974
                     /gene="wze"
                     /locus_tag="SPC48_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI34672.1"
                     /db_xref="GOA:Q4JYH5"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH5"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVSIARSFARAGYKTLLIDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDAFILVTATGDVNKRDVQKAKQQLEQAGKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            4990..6357
                     /gene="wchA"
                     /locus_tag="SPC48_0008"
     CDS             4990..6357
                     /gene="wchA"
                     /locus_tag="SPC48_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34673.1"
                     /db_xref="GOA:Q4JYH4"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH4"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETEVERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISKRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSILDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDVGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAVASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     misc_feature    5773..6354
                     /gene="wchA"
                     /locus_tag="SPC48_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 3.3e-146"
     gene            6388..7560
                     /gene="wchF"
                     /locus_tag="SPC48_0009"
     CDS             6388..7560
                     /gene="wchF"
                     /locus_tag="SPC48_0009"
                     /note="member of homology group 15"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34674.1"
                     /db_xref="GOA:Q4JYH3"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH3"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKAIQYYVACIR
                     ENSAKSGITEDVFEHNGAICYNVDVPNIGPARAIAYDIAAINRAIEIAKENKDEDPIF
                     YILACRIGPFIHGIKKKIQAIGGTLLVNPDGHEWLRAKWSAPVRRYWKISEGLMVKYA
                     DFLVCDSKNIEKYIQEDYKQYQPKTTYIAYGTDTTRSTLKSSDKKVRSWFKEKNISEN
                     EYYLVVGRFVPENNYESMIRGFLASNSKKDFVLITNVEQNKFYNQLLAKTGFDKDPRV
                     KFVGTVYEQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     QSAIYWKKDELSQVIEKVEQFDAKMIDELDRQSNQRIADSFTWEKIVTDYEKVFKG"
     gene            7566..8462
                     /gene="wcxG"
                     /locus_tag="SPC48_0010"
     CDS             7566..8462
                     /gene="wcxG"
                     /locus_tag="SPC48_0010"
                     /note="member of homology group 79"
                     /codon_start=1
                     /transl_table=11
                     /product="putative LicD-family phosphotransferase"
                     /protein_id="CAI34675.1"
                     /db_xref="GOA:Q4JYH2"
                     /db_xref="InterPro:IPR007074"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH2"
                     /translation="MAVKLKYDKSDITFLDDDELKKYQSELLKMISDVFTFFDENGIA
                     YSLSGGSILGAIRHKGFIPWDDDVDINIPRESYDKLFSLFESDNSLSRKYYLQSAKSH
                     PELGLHVSQIRKKGTVARRKYDHSAEECGISIDLYIVENVYNNPVKRFFQGYTSMFLT
                     FALASVRETKNHALMKEMFRLEGRKLNYSVGKLMVGWFFGIIPIEKWLNWLDKCNSSC
                     KDSHTKYVSIPTGRKHFRRETYLRENMNIYKKVPFETLMVNVPVWSEEYLEMFYGKDY
                     MVVPPVDKREQHLFLELSYGEE"
     misc_feature    7683..8384
                     /gene="wcxG"
                     /locus_tag="SPC48_0010"
                     /note="HMMPfam hit to PF04991, LICD Protein Family, score
                     1.2e-21"
     gene            8463..9182
                     /gene="abp1"
                     /locus_tag="SPC48_0011"
     CDS             8463..9182
                     /gene="abp1"
                     /locus_tag="SPC48_0011"
                     /note="member of homology group 57"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IspD-family transferase (arabinitol)
                     Abp1"
                     /protein_id="CAI34676.1"
                     /db_xref="GOA:Q4JYH1"
                     /db_xref="InterPro:IPR001228"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH1"
                     /translation="MKVAILTASGIGSRIGQDIPKQFIHVENKPVIIYTLEKFQNHPE
                     IDEICIVILKGWEQMVKAYAEQFGITKLKMITLGGKSGQESIYNGLRAVKKAHPNEDV
                     TVLIHDGNRPLVSNNIISNALATYQRFGNAVAAIPTTEVVFVLENPQSTSSTEALNRD
                     LLRRTQTPHVYHLDNILSLHEKALENGITDVAASCQLMQLFGGKSYFSLGSEKNLKIT
                     TVEDLDIFKALLSSTRDKWIK"
     misc_feature    8469..9158
                     /gene="abp1"
                     /locus_tag="SPC48_0011"
                     /note="HMMPfam hit to PF01128, Uncharacterized protein
                     family UPF0007, score 5.5e-17"
     gene            9185..10237
                     /gene="abp2"
                     /locus_tag="SPC48_0012"
     CDS             9185..10237
                     /gene="abp2"
                     /locus_tag="SPC48_0012"
                     /note="member of homology group 58"
                     /codon_start=1
                     /transl_table=11
                     /product="putative dehydratase/epimerase (arabinitol)
                     Abp2"
                     /protein_id="CAI34677.1"
                     /db_xref="GOA:Q4JYH0"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYH0"
                     /translation="MTLLLNKIYRQDVESSLETIVNINDLNGKSILITGASGLIGSSV
                     IDQLLLLNEIRNFNIKIICCGRKFESLEKRFGRQTEYLHFVFYDATKVPHFAFAVDYI
                     IHAASPASPELYVNQPVETMASNFLGMYNLLEYAKNAKVSNLVYISSSEVYGISTSNN
                     PLDENYIGTVDHLSVRSSYASSKRATETLCASFASEYGIKIMIVRPGHIYGPSAKDSD
                     NRVSSFFMTEAIAGRDIVMKSTGSQLRSYCYSLDCASAILSVLLSGGSGQAYNVSNPN
                     SIITIKQMAETISRVGNVKLTMAIPSNQDIKQTNPMQNASLRSDKLEGLGWKGLFSAE
                     KGIENTFQILKALRSN"
     misc_feature    9272..10222
                     /gene="abp2"
                     /locus_tag="SPC48_0012"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00063"
     misc_feature    9275..10003
                     /gene="abp2"
                     /locus_tag="SPC48_0012"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 1.4e-44"
     misc_feature    9275..10108
                     /gene="abp2"
                     /locus_tag="SPC48_0012"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00052"
     misc_feature    9278..10090
                     /gene="abp2"
                     /locus_tag="SPC48_0012"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 9.1e-05"
     gene            10249..11265
                     /gene="wcyS"
                     /locus_tag="SPC48_0013"
     CDS             10249..11265
                     /gene="wcyS"
                     /locus_tag="SPC48_0013"
                     /note="member of homology group 118"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI34678.1"
                     /db_xref="GOA:Q4JYG9"
                     /db_xref="InterPro:IPR008441"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG9"
                     /translation="MIFFLSFYLVTEFKMDGKLGSFLKLLKKVDGLRILKQYFKSGVL
                     FFAIFQILSQGFSKKSLEIVRNSVDNKILAKLRKKYLSYIVENKDRILRESAERQSSS
                     KVWILWLQGMNNAPEIVKLCYNSVVQNLPDKEAVLLTEDTYRNYVIFPNHVQQKIDKG
                     IISKTHLSDLLRLELLTLYGGIWIDATVFISSDKIPDYMLFSELFLFQKLKPGLDGNP
                     KRISSWYICAKSNHPILVLTKELLYQYWSEHNYMMDYFLMHDFMELSIETYPQEWNKV
                     IPFSSSPSHILLLRLFETFDKRMLEYVYQQISIHKLTYKYDTDICYTETYLNKILSEG
                     EIDA"
     misc_feature    10393..11238
                     /gene="wcyS"
                     /locus_tag="SPC48_0013"
                     /note="HMMPfam hit to PF05704, Capsular polysaccharide
                     synthesis protein, score 1.1e-56"
     gene            11255..12229
                     /gene="wcwY"
                     /locus_tag="SPC48_0014"
     CDS             11255..12229
                     /gene="wcwY"
                     /locus_tag="SPC48_0014"
                     /note="member of homology group 183"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="CAI34679.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG8"
                     /translation="MMHKKLALIIAYFGELPEYSKVFFNSLNYNPEIDLFLVTDQCVN
                     INIDNLIVIKKTFSEFKNDVQNLFDFKIVLDTPYKLCDYKPIYGMLFKDILYEYPFWG
                     YCDLDMVLGDVFSFLPENILDNYSKIYEYGHLTIYKNDPENNRRFMYEVGMNYQDVFT
                     TKVIKVFDETEGIQRKYELMGIPTYTPRDCADINPWKYQLNRVETGISKEKLNSFNHK
                     KQLFFWENGKIFRGFINPYTHKIEYDSFNYLHFQKREMKITFPFNSSTKAFFITNQGI
                     VEKKQGFNIKKEDFKKYNNYNLIREISKGLQRYYFIWKRRLLKYIFRR"
     gene            12238..13419
                     /gene="wzy"
                     /locus_tag="SPC48_0015"
     CDS             12238..13419
                     /gene="wzy"
                     /locus_tag="SPC48_0015"
                     /note="member of homology group 260"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI34680.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG7"
                     /translation="MKISITNLYIWMLTVMFILMWIPSVPIFNYVDELLTLMILPYVI
                     MNFRALLLKSRLVIIGAIGFLLIGLISTYLSDLSRPLIAIVSDFFTFIKFPITYLYFR
                     YLFTKQNSTYFLNILYILSKFVVVIAFICCLLNYSFELGMTYDIRFGIGSFQFIYNNP
                     GFFLALMVVCYSLINYSNNSGNFKYKILAILNMVATLRSVAFGVIALLLVLSVFIGRN
                     LRLYHLFILIPSIIFVGNGAISTYFGDLETPRKLLFQGGIKVFQKFFPLGAGFASYGS
                     NAAYVYYSPLYFQFGFHHIWGLNLEYGNIANDNFWPMIFAQFGFIGSIFYILMFMAIM
                     KDLFIKSMYKNQVVSLSLIIGHLLISSVGANIITGVLGVSMICAYASMAHVLDDVEVN
                     Y"
     gene            13416..14834
                     /gene="wzx"
                     /locus_tag="SPC48_0016"
     CDS             13416..14834
                     /gene="wzx"
                     /locus_tag="SPC48_0016"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI34681.1"
                     /db_xref="GOA:Q4JYG6"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG6"
                     /translation="MKLLKNYIYNLVYQIVAIILPLVTIPYASRVLGAEIIGINSYTN
                     TIISYFVLIANVGLTTYGNRTISYTRDSVLKRSQKFWEIFVIKIIMALFSLSLFFTFT
                     FIYREYTTFLYIQSIQILATAIDISWFFTGMEYFKRTVTRNILTKILSAICIIGFVKS
                     REDLWLYILILVLSTFLGNLTLWTYVFDAIEVINFKSLQLKEHIKPVFVLFIPQLATT
                     LFLTLNKLLLGNLSTLSQSGYFDSADKVIRILLTFITAIGTVIFPRLANSFNRGEKRN
                     VEELLKLSFGAINIIAFPMIVGIMVIGRPFSILFFGSEFEGIEIVLGILSIELVFMGW
                     SSVLGNQFLVAVNKTKGLTVSVFIASLILLISSFILIPMLGASGASISSVIGEATIAL
                     VQLYYVSKHTRLCLLFSDISKILVSSLIMGTTCLVIGSCFYDGIMKLCVQGTVGLMVY
                     CIMIWYSRTEIVNTILKKIKIQ"
     misc_feature    13422..14222
                     /gene="wzx"
                     /locus_tag="SPC48_0016"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 5.1e-55"
     gene            14896..15303
                     /gene="glf"
                     /locus_tag="SPC48_0017"
     CDS             14896..15303
                     /gene="glf"
                     /locus_tag="SPC48_0017"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34682.1"
                     /db_xref="GOA:Q4JYG5"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG5"
                     /translation="MIDQYFDYKHGELEYRSLRFEHEVLDEENYQGNAVVNYTEREIP
                     YTRIIEHKHCEYGTQPKTVITREYPADWKRGDEPYYPINDEKNNTMFAKYQEEAAKND
                     KVIFCGRLADYKYYDMHVVIERALSVVTNEFGY"
     misc_feature    14896..15240
                     /gene="glf"
                     /locus_tag="SPC48_0017"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 6.4e-37"
     gene            15360..16229
                     /gene="rmlA"
                     /locus_tag="SPC48_0018"
     CDS             15360..16229
                     /gene="rmlA"
                     /locus_tag="SPC48_0018"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI34683.1"
                     /db_xref="GOA:Q4JYG4"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG4"
                     /translation="MKGIILAGGSGTRLYPLTRVASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGGLSVEVMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     misc_feature    15363..16079
                     /gene="rmlA"
                     /locus_tag="SPC48_0018"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 5.2e-119"
     gene            16230..16823
                     /gene="rmlC"
                     /locus_tag="SPC48_0019"
     CDS             16230..16823
                     /gene="rmlC"
                     /locus_tag="SPC48_0019"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI34684.1"
                     /db_xref="GOA:Q4JYG3"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG3"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTASYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDL"
     misc_feature    16266..16796
                     /gene="rmlC"
                     /locus_tag="SPC48_0019"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 6.5e-16"
     gene            16836..17885
                     /gene="rmlB"
                     /locus_tag="SPC48_0020"
     CDS             16836..17885
                     /gene="rmlB"
                     /locus_tag="SPC48_0020"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI34685.1"
                     /db_xref="GOA:Q4JYG2"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG2"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVIGDIADAELVDKLATQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    16851..17807
                     /gene="rmlB"
                     /locus_tag="SPC48_0020"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.0001"
     misc_feature    16854..17594
                     /gene="rmlB"
                     /locus_tag="SPC48_0020"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 3.5e-77"
     misc_feature    16854..17651
                     /gene="rmlB"
                     /locus_tag="SPC48_0020"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0038"
     misc_feature    16857..17669
                     /gene="rmlB"
                     /locus_tag="SPC48_0020"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.2e-05"
     gene            17951..18802
                     /gene="rmlD"
                     /locus_tag="SPC48_0021"
     CDS             17951..18802
                     /gene="rmlD"
                     /locus_tag="SPC48_0021"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI34686.1"
                     /db_xref="GOA:Q4JYG1"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELNFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLVKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    17951..18799
                     /gene="rmlD"
                     /locus_tag="SPC48_0021"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 1.4e-144"
     misc_feature    17954..18583
                     /gene="rmlD"
                     /locus_tag="SPC48_0021"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.2e-19"
     misc_feature    17954..18595
                     /gene="rmlD"
                     /locus_tag="SPC48_0021"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00012"
     misc_feature    17957..18685
                     /gene="rmlD"
                     /locus_tag="SPC48_0021"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 2.4e-08"
     gene            18843..20047
                     /gene="glf"
                     /locus_tag="SPC48_0022"
     CDS             join(18843..18860,18859..19371,19371..19484,19460..20047)
                     /gene="glf"
                     /locus_tag="SPC48_0022"
                     /EC_number="5.4.99.9"
                     /note="member of homology group 6"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase Glf"
                     /protein_id="CAI34687.1"
                     /db_xref="GOA:Q4JYG0"
                     /db_xref="InterPro:IPR004379"
                     /db_xref="InterPro:IPR015899"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4JYG0"
                     /translation="MNSKGALKIYNYLVVGAGLFGAVFAHEAALKGKKVKVIEKRNHI
                     AGNIYTREEEGIQIYQYGAHIFHTSDKEIWDYVNQFAEFNRYINSPVANYKGEIYNLP
                     FNMNTFNKLWGVVTPAEAQAKIDEQRAILNGKTPENLEEQAISLVATDIYEKLIKDYT
                     EKQWGKPTTELPSFIIVLPVRLTYDNNYFNDTYQGIPIGGYTQIVEKCWIMKILMMLD
                     HENIDVETNVDFFVNKEQYLKDFPKIVFTGMIDEFFDYKLGELEYRSLRFENEALDME
                     NYQGNAVVNYTDAETPYTRIIEHKHFEFGSQAKTIITKEHSKTWEKGDEPYYPVNNDR
                     NNHLYKSYKKLADEQGNVIFGGRLGHYRYYDMHQVIGAALQCVRNELDSYSMKIKEQT
                     RKLAAGCSKHCFEVADGN"
     misc_feature    18843..18923
                     /gene="glf"
                     /locus_tag="SPC48_0022"
                     /note="Signal peptide predicted for SPC2084 by SignalP 2.0
                     HMM (Signal peptide probability 0.719) with cleavage site
                     probability 0.362 between residues 27 and 28"
     misc_feature    join(19300..19371,19371..19460,19484..19903)
                     /gene="glf"
                     /locus_tag="SPC48_0022"
                     /note="HMMPfam hit to PF03275, UDP-galactopyranose mutase,
                     score 2.1e-102"
     gene            complement(20115..21371)
                     /gene="tnp"
                     /locus_tag="SPC48_0023"
     CDS             complement(20115..21371)
                     /gene="tnp"
                     /locus_tag="SPC48_0023"
                     /note="member of homology group 13"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
                     /protein_id="CAI34688.1"
                     /db_xref="GOA:Q4JYF9"
                     /db_xref="InterPro:IPR002560"
                     /db_xref="InterPro:IPR012287"
                     /db_xref="UniProtKB/TrEMBL:Q4JYF9"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDS
                     RKLSDKQFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHSLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSRA"
     misc_feature    complement(20619..20915)
                     /gene="tnp"
                     /locus_tag="SPC48_0023"
                     /note="HMMPfam hit to PF01610, Transposase, score 1.3e-46"
     misc_feature    complement(20955..21020)
                     /gene="tnp"
                     /locus_tag="SPC48_0023"
                     /note="Predicted helix-turn-helix motif with score
                     1860.000, SD 5.52 at aa 118-139, sequence
                     ISMTDIAHQLSISTSTVIRKLN"
     gene            21703..>22062
                     /gene="aliA"
                     /locus_tag="SPC48_0024"
     CDS             21703..>22062
                     /gene="aliA"
                     /locus_tag="SPC48_0024"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI34689.1"
                     /db_xref="GOA:Q4K2T2"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="UniProtKB/TrEMBL:Q4K2T2"
                     /translation="MMKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKD
                     AKWYTSEGEEYAAVKAQD"
     misc_feature    21703..21789
                     /gene="aliA"
                     /locus_tag="SPC48_0024"
                     /note="Signal peptide predicted for SPC2086 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.277 between residues 29 and 30"
     misc_feature    21949..22017
                     /gene="aliA"
                     /locus_tag="SPC48_0024"
                     /note="PS01040 Bacterial extracellular solute-binding
                     proteins, family 5 signature."
BASE COUNT     7187 a   3283 c   4422 g   7170 t
ORIGIN
        1 cgaccgtcgc ttcctagttg tggctaactt gtccaatgaa gagcaagact taacagtaga
       61 aggaaaagtc aaatctgtct tgattgaaaa caccctagct caagaagtct ttgaaaaaca
      121 aatcttagtt ccatgggatg ctttctgtgt ggaattacta taaatatttt ttgcagaaaa
      181 atttaaaatt gaaatcatat aaaaacaagg gaggactgta taaaagacag aaatcctttg
      241 ttttttataa ccaaggttta taaactttca ttctcgaaat tcaattaact ttacaaattc
      301 ccactattaa ggagaaagaa gatgaacata aagaagcgtg tccttagtgc aggtctgact
      361 tttgcatctg ctttgctttt tgatatgagc ccatgttttc tcaataggat tgtactcagg
      421 tgagtaggga ggaagaggta aaagtttatg cccaaactcc tcgcataaaa gttctaactt
      481 acccattcta tggaatctta cattatccat aataataacc gatggtgtgg ttaatgttgg
      541 taagaaaaac ttctgaaacc aagattcaaa aaagtcgctc gtcatcgtct cttcgtaagt
      601 cattggagcg attaactcac catttgttag acctgcaacc aaagaaatcc tctgatatct
      661 tcttccagat actttgcctc ttattaactg accttttaat gagcgaccat attctcgata
      721 aaaataagta tcgaatcctg tttcatcaat ctaaacaggt gctaggtgct ttaaactatt
      781 aaaattctta agaaataagg ctattttttc tgggtcttgt tcatagtagg tgtggttctt
      841 tttttcgagt gtagcccata gctttgagcg catagtggat ggtagttgga tgacagccaa
      901 attcagaagc tatttcagtc aaataagcgt ctggattatc agtaagatag tttttaagtc
      961 tatctctatc aacttttctt ggttttgttc cttttacttg gtggtttagc tctcctgttt
     1021 tctcttttag ctttaaccag ccataaatgg tattacgtga gatttggaaa acgtgtgatg
     1081 cttctgttat actacctgtt cgctcacaat aagagagaac ttttttacga aaatctattg
     1141 aatatgccat aaaaagatta taccacattg tgtactatag tagattgaaa ctagagtagt
     1201 acacctctgc ttctaaaaca ttgttagaaa tcgatttaac tgtcctggtc gagttgtcct
     1261 gttcttgttt caatctacta tatttttgtt tcgcgggaag tctacttaag atacttaaag
     1321 atgcagatag taaaaaaaga tgtagacatt accgtaaaaa agtgatataa ttgtatgata
     1381 ttgaatgtat aggtgttaat cttgagtaga cgttttaaaa aatcacgttc acagaaagtg
     1441 aagcgaagtg ttaatatagt tttactgact atttatttat tgttagtttg ttttttattg
     1501 ttcttaatct ttaagtacaa tatccttgct tttagatatc ttaatctagt ggtaactgcg
     1561 ttagttctac tagttgcctt ggtagggctg ctcttgatta tctataaaaa agcagaaaag
     1621 ttcacgattt ttctgttggg attctctatc cttgtcagct ctgcgtcgct ctttgcagta
     1681 cagcagtttg ttggactgac caatcgttta aatgcgactt ctaattactc agaatattca
     1741 atcagtgtcg ctgttttagc agatagtgag atcggaaatg ttacgcaact gacgagtgtg
     1801 acagcaccga ctgggactga taatgaaaat attcaaaaac tactagctga tatcaagtca
     1861 agtcagaata ccgatttgac ggtcaaccag agttcgtctt acttggcagc ttacaagagt
     1921 ttgattgcag gggagactaa ggccattgtc ctaaatagtg tctttgaaaa tatcatcgag
     1981 tcagagtatc cagactacgc atcgaagata aagaagattt ataccaaggg attcactaaa
     2041 aaagtagaag ctcctaagat gtctaagaat cagtctttca atatctatgt tagtgggatt
     2101 gacacctatg gtcctattag ttcggtgtcg cgatcagatg tcaatatcct gatgactgtc
     2161 aatcgagata ccaagaaaat cctcttgacc acaacgccac gtgatgccta tgtaccaatc
     2221 gcagatggtg gaaataatca aaaagataaa ttaacccatg cgggcattta tggagttgat
     2281 tcgtccattc ataccctaga gaacctttat ggtgtagata ttaattatta tgttcgtttg
     2341 aattttacct catttttgaa attgattgac ttattgggag gggtagatgt tcataatgat
     2401 caagagtttt cagctctaca tgggaagttc catttcccag tagggaatgt ccatctagac
     2461 tctgagcagg ctctaggttt tgtacgtgaa cgctactcac tagccgatgg agaccgtgac
     2521 cgtggtcgca accaacaaaa ggtgattgtg gctatccttc aaaaattaac gtcaaccgaa
     2581 gcactgaaaa attatagtac gatcattaat agcttgcaag attctatcca aacaaatatg
     2641 ccacttgaga ctatgataaa tttggtcaat gctcagttag aaagtggagg gaattataaa
     2701 gtaaattctc aagatttaaa aggtacaggt cggacggatc ttccttctta tgcaatgcca
     2761 gacagtaacc tctatgtgat ggaaatagat gatagtagtt tagctgtagt taaagcagct
     2821 atacaggatg tgatggaggg tagatgaaat gatagacatc cattcgcata tcgtttttga
     2881 tgtagatgac ggtcccaagt caatagagga aagcaaggca cttttaagag aagcttataa
     2941 tcaaggaatt cgaatgattg tgtctacttc gcatcgtcga aaagggctgt ttgaaactcc
     3001 agaagaaaaa attgcaacaa attttattaa ggttcgtgaa attgcaaaag aagtagcaga
     3061 tgatttagtc atagcttatg gcgcagagat atactatact ctggatgctc tagaaaagct
     3121 agaaaaaaaa gaaattccta cccttaatga tagtcgttat gctttgattg agtttagcat
     3181 gcatacttcc tatcgtgaga ttcatgcggg attgagcaat attttgatgt tgggaatcac
     3241 gccagtaatt gctcatattg aacgttatga tgccttagag aataacgaaa aacgtgttcg
     3301 tgaactgatt gatatggggt gctatactca gataaatagt tatcatgttt taaaacctaa
     3361 gttctttggt gaaaaatata aattcatgaa aaagagagct cgatattttt tggaacgtga
     3421 tttagttcat gtagttgcaa gtgacatgca caatttagac agtagacctc catatatgca
     3481 acaggcatat gataccattg ctaagaaata tggagcgaaa aaagcgaaag aattttttgt
     3541 agataatccc agaaaaatta taatggatca attaatttag gagaaaatat gaaggaacaa
     3601 aacactttgg aaatcgatgt attgcaacta ttcagagctt tatggaaaag aaagttggtc
     3661 attttattag tggcaattat aacttcttca gttgcttttg cctacagtac ttttgttatc
     3721 aaacctgagt ttactagtac aactcggatt tatgtagtta accgtaatca ggaagagaag
     3781 tctggtttaa ccaatcaaga cttgcaggca ggatcatact tggttaaaga ctatcgtgaa
     3841 attatcctat cgcaggatgt tttggaggaa gttatttctg atttgaaact agatttgacg
     3901 ccaaaaggtt tggctaataa aattaaagta acagtaccag ttgatacccg tattgtctct
     3961 atttcagtta atgatcgagt ttctgaagag gcaagccgta tcgctaactc tttgagagaa
     4021 gtagctggtc aaaaaattat cagtattact cgtgtttccg atgtgacaac actagaggag
     4081 gcaagaccga cgatatcacc gtcttcgcca aatattaaac gcaatacact aattggtttt
     4141 ttggcagggg ggattggaac tagtgttata gttcttcttc ttgaactttt ggacactcgt
     4201 gtgaaacgtc cggaagatat cgaagataca ctgcagatga cacttttggg agttgtacca
     4261 aacttgagta agttgaaata ggagagagga atgccgacat tagaaatagc acaaaaaaaa
     4321 ctggagttca ttaagaaggc agaagaatat tacaatgcct tatgtacaaa tatacagttg
     4381 agcggagata aactaaaagt aatttccgtt acttctgtta accctgggga aggaaaaaca
     4441 actacttctg taagtatagc aaggtcgttt gcgcgtgcag gctataaaac tcttttgatc
     4501 gatggcgata ttcgaaattc agttatgtca ggatttttta aatctcgtga aaaaattaca
     4561 gggctaacag aatttttatc tgggacagct gatttatctc acggtttatg tgatacaaat
     4621 attgaaaatt tatttgtagt tcaatcggga actgtatcac caaaccctac agccttgtta
     4681 caaagtaaaa attttaatga tatgattgaa acattgcgta aatattttga ctatatcatt
     4741 gttgatacac cacctattgg aattgttatt gatgcggcaa ttatcactca aaagtgtgat
     4801 gcgttcatct tggtaacagc aacaggtgat gtgaataaac gtgatgtcca aaaagcgaaa
     4861 caacaattag aacaagcagg gaaactgttc ctgggagttg ttttaaataa attagatatc
     4921 tcggttgata agtatggcgt ttacggttcc tacggaaatt atggtaaaaa ataatttagg
     4981 aaagatttta tggatgaaaa aggattgaaa atttttctgg cagtattaca gagtattatt
     5041 gtcattttat tggtttattt tcttagcttt gttagagaga cagaagttga acgttcttcg
     5101 atggttatac tataccttct ccactttttt gtattctatt ttagttccta tggtaacaat
     5161 ttttttaaaa gagggtacct agttgagttt aatagtacta taagatatat ttttttcttt
     5221 gcaatagcta taagtgtatt aaactttttt atagcggaac ggtttagtat atctaaaaga
     5281 ggaatggtat acttcttaac tttagaagga atatccttat acttgttaaa tttcttagta
     5341 aaaaaatatt ggaagcatgt gttttttaat ctaaaaaata gcaagaaaat tttactgtta
     5401 acagtaacga aaaatatgga aaaagttctt gataaattgc tagaatctga tgaactttca
     5461 tggaaattgg tagcagtaag tattttggat aaatctgatt ttcaacatga taaaatacct
     5521 gtaattgaga aggaaaaaat tattgaattt gcaacgcatg aagttgtgga tgaggtgttt
     5581 gtcaatcttc caggagagag ctacgatgtt ggagaaatta tctctaggtt tgagacaatg
     5641 gggatagatg taactgtaaa tcttaaagca tttgataaga atttgggtcg caataaacaa
     5701 attcatgaga tggtaggatt gaatgtagtc actttctcta caaattttta taaaactagt
     5761 catgtgattt caaagagaat tctcgatatt tgtggtgcca ctattggcct tattcttttt
     5821 gctgtagcta gtctagtttt agttccattg attcgtaaag atggcggacc agctattttt
     5881 gctcaaactc gtatagggaa aaatggtcga catttcacct tttataaatt ccgttcaatg
     5941 cggatcgatg ctgaagctat caaagaacag ttgatggatc aaaatacgat gcaaggtggt
     6001 atgtttaaga tagacaatga tcctcgtgtt acaaaaattg gtcgctttat tcgtaaaacc
     6061 agtttggatg aattgccgca gttttggaat gtctttatag gagatatgag tttggtggga
     6121 acacgtccac ctacagtaga cgagtatgat cagtatactc cagaacagaa acgtcgactc
     6181 agctttaaac ctggtattac aggtttatgg caggttagcg gccgtagtaa aataaccgat
     6241 tttgacgatg ttgtaaaatt agatgtggct tatattgata attggacaat ctggaaagat
     6301 attgaaattt tgcttaaaac tgttaaagtt gtatttatga gagatggagc gaagtaattt
     6361 ctgtatatcc atcatattag gagagaaatg aaaaagtcag tttatatcat tggttcaaaa
     6421 ggaattcctg ctaagtatgg aggatttgaa acttttgttg aaaaattaac agccttccaa
     6481 caagataagg ctatccaata ttatgtggct tgtatacgtg aaaactctgc aaaatcaggg
     6541 attactgagg atgtttttga acataatggt gctatctgtt ataacgtcga tgttcctaat
     6601 attggtccag cgcgagctat agcgtatgat atcgctgcaa ttaacagagc tattgaaatt
     6661 gccaaagaaa ataaggatga agatccaatc ttctatattt tagcttgtcg aattggtccg
     6721 ttcatccatg gaattaagaa aaaaatccag gcgataggtg ggactcttct agttaatcca
     6781 gatggccacg agtggttgcg agctaagtgg agtgctcctg ttcgtcgcta ctggaaaatt
     6841 tctgaaggtc ttatggtcaa atatgcagat tttttagtgt gtgatagtaa gaatattgaa
     6901 aaatatatcc aagaagatta taaacagtat caacctaaaa caacctatat cgcttatgga
     6961 acagatacaa cacgctctac attaaagagt agtgataaaa aagtacgttc ttggttcaaa
     7021 gagaagaata tttctgagaa cgagtattat ctagttgtag gacgttttgt accagaaaac
     7081 aactatgaat ctatgattcg tggctttctg gcgtctaact ctaagaagga ctttgtctta
     7141 atcacaaatg tagaacagaa taaattttat aatcagttgt tggcaaaaac tggttttgat
     7201 aaggacccac gagtaaaatt tgtaggtaca gtctatgagc aagagcttct taaatatatt
     7261 cgtgaaaacg cctttgctta cttccacggg catgaagttg gtggaaccaa tccttcgctt
     7321 ttagaagctc tggcatcaac taaactgaat ttattgctag atgttggctt taaccgagaa
     7381 gttggggagc aaagtgcgat ctattggaaa aaagatgagc tttcccaagt aatcgagaaa
     7441 gttgaacaat ttgatgcaaa aatgattgat gagttagata gacaatcaaa tcagagaatt
     7501 gcggattctt tcacttggga aaagattgtc acagactacg agaaagtatt taaaggttag
     7561 agttaatggc agtaaaatta aaatatgata aatcagatat tacattttta gatgatgacg
     7621 aattgaaaaa ataccaatca gaattgttga aaatgatatc agatgtgttt actttttttg
     7681 atgaaaatgg gatagcgtat tctttaagtg gaggtagcat tttaggggca atccgtcata
     7741 aagggtttat cccttgggat gatgatgttg atatcaatat tccgagggaa agttacgata
     7801 aactattttc tctatttgag tcagacaata gtcttagtcg taaatattat cttcaatcag
     7861 caaaaagtca tccagaatta ggacttcatg tttctcaaat tagaaaaaaa ggaacagttg
     7921 ctcgtaggaa atacgatcat tcggctgagg agtgcggtat ttctatagat ctttacattg
     7981 tagaaaatgt atacaataat ccagtgaaac gattctttca aggttataca agtatgtttt
     8041 tgacttttgc cttggcttct gtacgagaaa caaagaacca tgccctgatg aaggaaatgt
     8101 ttagactgga aggtagaaaa ctaaattatt cagttggaaa gttaatggtt ggttggtttt
     8161 ttggaattat tccaattgaa aagtggttga attggcttga taaatgtaat tcaagctgta
     8221 aggattcaca tacaaaatat gtatccatac ctacaggaag gaaacacttt agacgcgaga
     8281 cttacttgcg agagaatatg aatatttata aaaaggttcc ttttgaaact ttgatggtga
     8341 atgttcctgt ttggtcagaa gagtatttag aaatgtttta cggtaaagat tatatggtcg
     8401 ttcctcctgt tgataagaga gagcaacatt tgtttttaga gttgagttac ggagaagaat
     8461 aaatgaaagt agcaatatta actgcttcag gtatcgggag caggattggt caagatatcc
     8521 ctaaacaatt tattcatgtt gaaaataagc cagtcattat ctataccctt gaaaaatttc
     8581 aaaatcatcc agaaattgat gaaatctgta ttgtcatttt aaaagggtgg gagcagatgg
     8641 ttaaggctta tgcggaacaa tttggaatta caaagttaaa gatgataact ttgggaggga
     8701 agtctggtca agaatcaatt tataacggtc ttagagcagt taagaaagct catcccaatg
     8761 aggatgtgac tgtattaatt catgacggga atcgtccttt agtgagcaat aatattatta
     8821 gtaacgcttt agcaacatac caacggtttg gaaatgctgt tgcagctata ccaacgactg
     8881 aggtagtatt tgttttagaa aacccacaat caacttcgtc cacagaagca ttgaatcgtg
     8941 acttgttgag acgaacacaa actcctcatg tttaccatct tgataatatt ctatcgcttc
     9001 atgaaaaagc attagaaaat gggataactg atgttgcagc atcatgccaa ctcatgcaac
     9061 tattcggtgg aaagagttat ttctctcttg gatcagagaa aaacttgaaa attacgactg
     9121 tagaagatct cgatattttt aaagccttat tgagttcaac tcgagataag tggattaaat
     9181 agtaatgaca ttattattaa ataaaatata tagacaagat gtagaatctt ctctagaaac
     9241 aatcgtcaat attaatgatt tgaatggcaa gtcaatttta attactggag cttctggttt
     9301 gattggttca agtgtcattg accagttatt attgctaaat gaaataagga attttaacat
     9361 taaaattatt tgttgcggaa gaaagtttga atcattagaa aaacgatttg gtagacaaac
     9421 agagtattta cactttgtgt tctatgatgc gactaaagta cctcactttg cttttgcagt
     9481 ggactacatt attcatgctg ctagtcctgc tagtcctgaa ttatatgtta atcagcctgt
     9541 agaaacaatg gctagtaact ttctgggcat gtataatcta ctggaatacg ccaaaaatgc
     9601 taaagtttca aatctagttt atatctcatc tagtgaagtt tatggaatta gcactagtaa
     9661 taatcctttg gacgaaaatt atattggaac tgttgatcat cttagcgtac ggtcttctta
     9721 tgccagttca aaaagagcta ctgaaacact ttgtgctagt tttgcttccg agtatggaat
     9781 caaaataatg atagtaaggc caggacatat ctatggtcct agtgccaagg actctgataa
     9841 tcgtgtatca tcatttttta tgacagaagc gattgctggg cgtgatattg tcatgaaaag
     9901 tacaggtagt cagttaagat cctattgtta tagtttggat tgtgccagtg caattctaag
     9961 tgttctcctt tcgggtgggt caggacaagc ttataatgtt tccaatccaa attcaattat
    10021 tactataaaa cagatggctg aaactatttc acgagttggc aatgtgaaac ttaccatggc
    10081 tattcctagt aatcaagata ttaaacagac caatcctatg cagaatgcca gtcttaggag
    10141 tgataagtta gaaggattgg gatggaaagg attgttttct gctgaaaaag gtatagaaaa
    10201 tacattccaa attttgaaag cattaagaag caattagata gattaaattt gatatttttc
    10261 ttatcatttt acttagtaac ggagtttaaa atggatggta aattaggttc ttttttgaaa
    10321 ttattaaaaa aagtagatgg cttaaggatt ttaaaacagt attttaagtc tggggtacta
    10381 ttttttgcta tttttcaaat actatctcaa ggtttttcaa aaaagtcttt agaaattgtt
    10441 cgtaattcag tagataataa aatattagct aaattgagga aaaaatacct ttcctatata
    10501 gttgaaaata aagatagaat tttacgggaa tcggctgaac gtcaatcttc tagtaaggtg
    10561 tggatattgt ggttacaggg gatgaacaat gctcctgaga tcgtaaagtt atgttataat
    10621 tctgtggttc aaaatctccc tgataaagag gcagttcttt taacggaaga tacttataga
    10681 aattatgtaa tctttccaaa tcatgttcaa cagaagattg ataaaggaat catttctaaa
    10741 acacacctgt ctgatttgtt gagattagaa ctgctaactc tgtatggagg tatttggatt
    10801 gatgcgactg tttttatatc ttccgataaa atccctgatt atatgttgtt ttctgaatta
    10861 tttttattcc aaaaattgaa accagggtta gatggaaatc ctaagagaat ttcaagttgg
    10921 tatatttgtg cgaagtctaa tcatccaata cttgttctta ccaaggagtt gttgtatcaa
    10981 tattggtcgg aacacaatta tatgatggac tactttttaa tgcatgattt tatggaatta
    11041 tcaattgaga catatccaca agaatggaat aaagtgattc cattctctag ttctccttcc
    11101 catatactgc tattaagatt atttgaaaca tttgataaga ggatgctaga atatgtttat
    11161 caacaaattt ctatacataa actaacttat aaatatgata ctgatatctg ttatactgaa
    11221 acctacttga ataaaatact aagtgaagga gagattgatg cataaaaagt tagctctaat
    11281 aatagcatat tttggtgaat tacctgaata ctctaaagtt ttttttaatt ctttaaatta
    11341 taatcctgag attgatttat ttctagtgac ggatcaatgt gtaaatataa acatagataa
    11401 tttaattgtt ataaaaaaaa cgttctctga atttaaaaat gatgttcaaa atttatttga
    11461 tttcaaaata gttttagata ctccttataa attatgtgat tacaagccta tatatgggat
    11521 gctttttaaa gatattttat atgaatatcc attttgggga tattgtgatt tggatatggt
    11581 gctgggagat gtgttttcgt ttttacctga aaatatattg gataattaca gcaaaatata
    11641 tgaatatggt catttaacta tttataaaaa tgaccctgaa aataatcgac gtttcatgta
    11701 tgaagttgga atgaattacc aagacgtttt tacaactaaa gttattaaag tatttgatga
    11761 gacagaagga attcagagaa aatatgaatt aatgggaatt cctacatata caccaagaga
    11821 ttgtgctgat ataaaccctt ggaagtatca gttaaataga gtagaaacag gtatttccaa
    11881 agaaaaatta aattcattta atcataaaaa gcagttgttt ttctgggaaa atggtaagat
    11941 ttttagagga tttatcaacc catatacaca taaaatagag tacgattctt tcaattatct
    12001 tcattttcaa aaaagagaaa tgaagataac ctttcctttt aattctagta caaaagcatt
    12061 ttttattact aatcaaggga ttgtagagaa gaagcagggg tttaatataa aaaaagaaga
    12121 ttttaaaaaa tataataact ataacttaat aagagaaata tcgaaaggtt tacaacgata
    12181 ttatttcatc tggaaaagga gattattaaa atatatattt aggagataac ttcaataatg
    12241 aaaatttcaa ttacaaattt atatatatgg atgttgacag taatgtttat attaatgtgg
    12301 attccaagtg ttcctatatt taattatgta gatgaactat taacgttgat gatacttccg
    12361 tatgtgatta tgaattttag agctcttcta ctaaaaagta gattagtaat tataggtgca
    12421 attggttttt tattaatagg attaatatca acataccttt cagatcttag ccgccctttg
    12481 atagctatag tatcggattt tttcacattt attaagtttc ctattaccta tttatatttt
    12541 agatatttat ttacaaaaca aaattcaact tattttttga atattttata tattcttagt
    12601 aagtttgttg tggttattgc ttttatttgc tgtttattaa attatagttt tgaactaggc
    12661 atgacctatg atatccgctt tggaataggt agttttcagt ttatatataa taacccagga
    12721 ttttttctag ccttgatggt tgtttgttat tcacttataa attactctaa taattcaggt
    12781 aattttaaat ataaaatttt agctatttta aatatggttg caactctacg atcagtggca
    12841 tttggagtta ttgccctact gctagttttg agtgtgttta taggaagaaa tttaagatta
    12901 tatcacttat ttatattgat tccgtcgatt atttttgtag gtaatggtgc tataagtaca
    12961 tatttcggtg atttggaaac acctagaaaa cttctattcc agggaggtat aaaggttttt
    13021 cagaaatttt tcccattagg ggcaggtttt gcttcatatg ggagcaacgc tgcttatgtg
    13081 tattactctc ccctgtattt tcaatttggt tttcatcata tttggggtct taatttagaa
    13141 tatgggaata tagctaatga taacttttgg ccgatgattt ttgcacagtt tggttttatt
    13201 ggttctatat tttatatact gatgttcatg gctattatga aggatttatt cattaaatct
    13261 atgtataaaa atcaagtggt atctttatct ttaattatag gtcatttgtt aatttcctca
    13321 gttggtgcaa atataattac tggtgtgtta ggtgtaagta tgatatgtgc atatgcctca
    13381 atggctcatg ttttagatga tgtagaggta aattattgaa attattaaaa aactacatat
    13441 ataatttggt ttatcaaata gtagctatta ttttaccatt ggtgaccatt ccatatgctt
    13501 ctagggtctt aggtgcagaa ataattggta ttaattcata tacaaataca attatttctt
    13561 actttgttct gattgcaaat gttggattaa ctacttatgg gaatagaacg atttcgtata
    13621 ctagagattc tgttttaaaa agaagtcaaa aattctggga aatctttgtc ataaaaatta
    13681 ttatggcttt gttttcattg tcactgtttt ttacctttac atttatttat agagagtata
    13741 caactttctt atatatacag tctattcaaa tccttgcaac agcaatagat atttcttggt
    13801 tttttacagg aatggaatat tttaaaagaa cagtcactag aaatatattg acaaagatat
    13861 tatctgcaat ttgtattatt ggatttgtta aaagtaggga agatttatgg ttatatatat
    13921 taattttagt tctctcaact tttttaggga atttaacttt atggacatat gtttttgatg
    13981 cgattgaagt aattaatttt aaaagcttgc aacttaaaga gcatattaaa cctgtatttg
    14041 tgttatttat acctcaattg gcaacaactc tttttctcac attaaacaaa ttgttgttag
    14101 gaaacttatc aacattatct caatctggct attttgatag tgcagacaaa gtgatacgaa
    14161 ttttactgac atttatcaca gctattggga cagtaatttt tccaagactg gcgaatagct
    14221 ttaatagagg agaaaaaaga aatgtcgaag aattattaaa actatctttt ggtgctatta
    14281 atattattgc tttcccaatg attgttggta ttatggtaat cggaaggcca ttttcaatcc
    14341 ttttttttgg aagtgaattt gaaggaattg aaattgtttt ggggatatta tcaatagaat
    14401 tggtttttat gggctggtca tcagtcttag gtaaccaatt tttagtagct gttaataaga
    14461 cgaagggctt aactgtttca gtgtttattg cttcattaat cttgctcata tcctctttca
    14521 tattgattcc tatgttagga gcttctggag cttcaatttc atcagttata ggagaggcga
    14581 caatagcttt ggtgcagtta tattatgttt caaaacatac tagattatgt ttattattta
    14641 gtgatatttc taaaatttta gtttctagtc tcataatggg aacgacttgt ttggtaattg
    14701 ggagttgttt ttatgatggt attatgaaac tctgtgttca aggaacagtt ggtttaatgg
    14761 tatattgtat aatgatttgg tatagcagga ctgaaattgt aaatactata cttaaaaaaa
    14821 taaagataca gtagtgaaaa atatttatag agatttttac tgcaaataat tgcaaataaa
    14881 gttgtcttca ctggaatgat tgaccagtac tttgattaca aacacgggga gttagaatac
    14941 cgtagccttc gttttgaaca cgaagtcttg gatgaagaaa attatcaagg gaatgcagta
    15001 gtaaactata cagaacgtga gattccttac actcgtatca ttgagcacaa gcactgtgag
    15061 tatggtacac aaccgaagac ggttatcact cgtgagtacc cagctgattg gaaacgtgga
    15121 gatgaaccat attatccgat caacgatgaa aagaacaaca ctatgtttgc taagtatcaa
    15181 gaagaagcag caaaaaatga caaggttatc ttctgtgggc gcctagctga ctataaatac
    15241 tacgacatgc atgttgttat tgaacgtgca cttagtgtag taacgaatga gtttggttac
    15301 taagacatac atttttaaca atataatgat tgttcaacaa caaagaaagg taccctacta
    15361 tgaaaggtat tattctagca ggtggttcgg ggacacgttt atatcctttg actcgcgttg
    15421 catcaaaaca acttatgccg gtttatgata aaccgatgat ttactaccca ctttcaacat
    15481 tgatgttggc tgggattagg gatattttga ttatttccac tccacaggat ttacatcgat
    15541 ttcaagagct tcttcaagac ggatctgagt ttgggatcaa actttcttat gcagagcaac
    15601 caagtccaga tggtttggca caagccttta tcattgggga agagtttatt tctgatgata
    15661 gcgttgcgct aatcttaggt gataatatct accatggttc tggactttcc aagatgctac
    15721 aaaaggcagc gagtaaggag tcgggagcaa ctgtttttgg ctaccatgtc aaggatccag
    15781 agcgctttgg tgtggttgag tttgatcagg atatgaaggc tatttctatt gaagaaaagc
    15841 cagagcaacc tcgttcaaac tatgcagtta caggtctcta tttctatgat aatgatgtag
    15901 tagagattgc caagagtatt aaaccaagtc ctcgtggtga actggaaatt acagatgtaa
    15961 acaaggctta tctagatcgt ggaggcttat ccgttgaggt tatgggacgt ggctttgctt
    16021 ggttggatac tggcactcat gaaagtttac tagaggcttc gcagtacatc gaaacagtcc
    16081 aacggatgca aaatgttcag gtagcaaact tggaagaaat tgcctatcgc atgggttata
    16141 tcagtcgtga agatgtattg accttagccc aaccacttaa gaaaaatgaa tacggacagt
    16201 atctgctccg tttgattgga gaagcataga tgacagataa ttttttcggt aagacgcttg
    16261 cggcacgcaa ggttgaagct attccaggca tgttggagtt tgatatcccc gttcatggag
    16321 ataatcgtgg ctggtttaaa gaaaatttcc aaaaggaaaa aatgcttcca cttggatttc
    16381 cagagtcttt ctttgcagaa ggaaaattgc aaaacaatgt atccttctca cgtaaaaatg
    16441 tccttcgtgg cctccacgca gagccttggg ataagtacat ctctgtggca gatggaggga
    16501 aagttctggg ttcttgggtt gatctacgcg agggtgaaac ctttgggaat acctatcaga
    16561 cagtaattga tgcaagcaag ggaatctttg ttcctcgagg cgtagctaat ggcttccaag
    16621 ttttatcaga tacagcttca tatagctatc tggtcaatga ttactgggcg cttgaactca
    16681 aacccaagta tgcctttgtg aactacgctg atccaagcct tggtattgaa tgggaaaatc
    16741 tggaagaagc agacgtatct gaagcagaca aacatcatcc cctacttaag gacgtgaagc
    16801 ctttgaaaaa agaagatttg taaaaaggaa agaatatgac tgaatacaaa aatattatcg
    16861 tgacaggtgg agctggcttt atcggttcta actttgtcca ttatgtttac gagaactttc
    16921 cagatgttca tgtgacagtc ctagataagt tgacttatgc tggaaaccgc gcgaatattg
    16981 aggaaatttt aggtaatcgt gttgagttag ttattggtga cattgctgat gcggagttgg
    17041 tagacaagtt ggctactcaa gcagatgcta tcgttcatta tgcagcggaa agccacaatg
    17101 ataattcgct caatgatcca tcgccattta ttcatactaa cttcatcgga acctatactc
    17161 ttttagaagc tgctcgtaag tatgatattc gcttccacca tgtatcgaca gatgaagttt
    17221 atggggatct ccctttacgc gaagatttgc caggtcatgg tgaaggacca ggtgagaaat
    17281 ttactgctga aacaaaatac aacccaagct ctccgtactc atcaaccaag gcagcctcag
    17341 atttgattgt caaagcctgg gtgcgttctt ttggagtcaa ggcaacgatt tccaactgtt
    17401 caaataacta cggtccttat caacatattg agaagtttat tccacgacaa atcaccaata
    17461 tcttgagcgg tatcaagcca aaactttacg gtgaaggtaa gaacgttcgt gactggattc
    17521 ataccaatga ccattcttca ggagtttgga caatcttgac aaaagggcaa atcggtgaaa
    17581 cctacttgat tggggctgat ggtgagaaga acaataagga agttttggaa cttatcctta
    17641 aggaaatggg acaagctgcg gatgcctatg atcatgtgac tgaccgtgca ggacatgacc
    17701 ttcgctatgc gattgatgct agcaagctcc gtgatgagtt gggatggaaa cctgaattta
    17761 ccaactttga agctgggctc aaggcaacaa tcaagtggta tacagataac caagaatggt
    17821 ggaaagcaga gaaagaagct gttgaagcca attatgctaa gactcaggag attattacag
    17881 tataaaaagc aggaaatagc tgctttttat tgctatattg ggaagagtta catattagaa
    17941 agatctagag atgattttaa ttacaggggc aaatggccaa ttaggaacgg aacttcgcta
    18001 tttattggat gaacgtaatg aagaatacgt ggcagtagat gtggctgaga tggatattac
    18061 caatgaagaa atggttgaga aagtttttga agaggtgaaa ccgactttag tctaccattg
    18121 tgcagcctac accgctgttg atgcagcaga ggatgaagga aaagagttga acttcgccat
    18181 caatgtgacg gggacaaaaa atgtcgcaaa agcatctgaa aagcatggtg caactctagt
    18241 ttatatttct actgactatg tctttgacgg taagaaacca gttggacaag agtgggaagt
    18301 tgatgaccga ccagatccac agacagaata tggacgcact aagcgtatgg gggaagagtt
    18361 agttgagaag catgtgtcta atttctatat tatccgtact gcctgggtat ttggaaatta
    18421 tggcaaaaac ttcgttttta ccatgcaaaa tcttgcgaaa actcataaga ctttaacagt
    18481 tgtaaatgac cagtacggtc gtccgacttg gactcgtacc ttggctgagt tcatgaccta
    18541 cctagctgaa aaccgcaagg aatttggtta ttatcatttg tcaaatgatg cgacagaaga
    18601 cacaacatgg tatgattttg cagttgaaat tttgaaagat acagatgtcg aagtcaagcc
    18661 agtagattcc agtcaatttc cagccaaagc taaacgtccg ctaaactcaa cgatgagtct
    18721 ggtcaaagcc aaagctactg gatttgttat tccaacttgg caagatgcat tgcaagaatt
    18781 ttacaaacaa gaagtgagat aagtagtaga atgattttct agtctaataa aagaggcaga
    18841 taatgaactc caaaggagct taagatatac aattatcttg ttgttggtgc tggtctcttt
    18901 ggtgcagtct ttgcccatga agcggcctta aaaggaaaaa aagtaaaagt tattgaaaaa
    18961 cgaaatcata tcgcgggtaa tatctatact cgtgaagagg aaggaattca aatttatcaa
    19021 tatggtgctc atatcttcca tacttctgat aaggagatct gggattatgt aaatcagttt
    19081 gcagagttta accgttacat aaattctcct gttgcaaact ataagggtga gatttataac
    19141 cttcctttta atatgaatac tttcaataaa ctctggggag ttgtaacgcc agcagaagca
    19201 caagctaaga ttgatgaaca acgtgctatt ttaaatggta aaactcctga aaatttggaa
    19261 gaacaggcga tttctcttgt agctacagac atctacgaaa aattaatcaa agactataca
    19321 gagaaacagt ggggcaaacc aactactgaa cttccatcct ttattattgt ttgccagtac
    19381 gcctgaccta tgataacaac tattttaacg atacctatca agggattcca attggtggat
    19441 acactcaaat agttgaaaaa tgttggatca tgaaaatatt gatgtagaaa caaacgttga
    19501 tttctttgtg aataaagagc aatatctgaa agattttcct aagattgtct ttactggtat
    19561 gattgatgaa ttctttgact ataagttggg cgaactagag taccgtagtc ttcgttttga
    19621 aaatgaggcc ttggatatgg aaaattacca aggaaatgca gttgtgaact atacggatgc
    19681 agaaacccca tatactcgca ttattgaaca caaacatttt gagtttggga gtcaagcaaa
    19741 gactatcatt actaaagaac attctaaaac atgggaaaaa ggtgatgagc cttattatcc
    19801 agttaataat gatcgtaata atcatttgta taaatcatat aaaaaacttg ctgatgagca
    19861 agggaatgtt atctttggtg gccgcttagg acactatcgt tattacgata tgcaccaagt
    19921 aattggagca gctttgcagt gcgtgagaaa tgagttagat tcatactcaa tgaaaatcaa
    19981 agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgcagatgg
    20041 aaactgacgc ggtttgaaga gattttcgaa gagtataaac aggctctttg tcaactgtag
    20101 tgggttgaag tcagctaagc tcgagaaagg acaaattttg tcctttcttt tttgatattc
    20161 agagcgataa aaatccgttt tttgaagttt tcaaagttcc gaaaaccaaa ggcattgcgc
    20221 ttgataagtt tgatgagatt attggtcgct tccaatttgg cgttagaata gtgtagttga
    20281 agggcgttga cgattttctc tttgtccttt agaaaggttt taaagacagt ctgaaaaaga
    20341 gaatgaacct gctttagatt gtcctcaata agtccgaaaa atttctctgg ttccttattc
    20401 tggaagtgaa aaagcaagag ctgatagagc tgatagtgat gtttcaagtc ttccgaatag
    20461 ctcaaaagct tgtttaaaat ctctttattg gttaaatgca tacgaaaagt aggacgataa
    20521 aattgcttat cactcagttt acggctatcc tgttgaatga gtttccagta gcgcttgata
    20581 gccttgtatt catgggattt tcgatgaaac tgattcatga tttggacacg cacacgactc
    20641 atagcacggc taagatgttg tacaatgtga aagcgatcca acacgatttt agcacatggg
    20701 aaaagttgtc tagctaagtc atagtaagga ctaaacatat ccatagtaat aattttgacg
    20761 cgacatcgga cggctctatc atatttaaga aagtgatttc gaatgatagc ttgtgttctt
    20821 ccctcaagaa cagtgatgat attgagattg ttaaaatctt gcgcaatgaa gctcatcttt
    20881 ccctttgtaa aagcatactc atcccaagac ataatctcag gaagacaaga aaaatcatgt
    20941 ttaaagtgaa agtcattgag cttacgaata acagttgaag ttgagatgga aagctgatgg
    21001 gcaatatcag tcatagaaat cttttcaatt aacttttgag caatcttttg gttgatgata
    21061 cgagggattt ggtgattctt cttgacgata gaagtttcag cgaccatcat ttttgaacag
    21121 tgatagcact tgaatcgacg ctttctaagg agaattctag taggcatacc agtcgtttca
    21181 agataaggaa ttttagaagg tttttgaaag tcatatttct tcaattggtt tccgcactca
    21241 gggcaagatg gggcgtcgta gtccagtttg gcgatgattt ccttgtgtgt atccttattg
    21301 atgatgtcta aaatctggat attagggtct ttaatgtcta gtaattttgt gataaaatgt
    21361 aattgttcca tatgattctt tctaatgagt tgttttgtcg cttttcatta taggtcatat
    21421 gggacttttt ttctacaata aaataggctc cataatatct atagtggatt tacccactac
    21481 aaatattata gaacctataa acaagtaaaa ctgactacca gttattattt agaaatagta
    21541 ttaaaaattc cttgactatg tgatatagtt gaggaatttt taaatgatat tcatattttt
    21601 tgcaaagatg ttgtttgaaa aataattttc aaaaattctg aaaattctgt tgacatcttt
    21661 ctgaaaagag tctataatgg agagaaagtt ttaaaggaga aaatgatgaa aagttcaaaa
    21721 ctatttgccc ttgcgggcgt gacattattg gcggcgacta ctttagctgc atgctctgga
    21781 tcaggttcaa gcactaaagg tgagaagaca ttctcataca tttatgagac agaccctgat
    21841 aacctcaact atttgacaac tgctaaggct gcgacagcaa atattaccag taacgtggtt
    21901 gatggtttgc tagaaaatga tcgctacggg aactttgtgc cgtctatggc tgaggattgg
    21961 tctgtatcca aggatggatt gacttacact tatactatcc gtaaggatgc aaaatggtat
    22021 acttctgaag gtgaagaata cgcggcagtc aaagctcaag ac
//
