LOCUS       CR931637               19969 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain Ambrose (serotype 5).
ACCESSION   CR931637
VERSION     CR931637.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19969)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 19969)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from wzg to aliA and is likely to be responsible for the
            expressed capsule serotype. For this particular strain a cps gene
            cluster appears to have deleted from the dexB-aliA locus. For a
            detailed description of how CDS products were predicted see the
            associated publication.
FEATURES             Location/Qualifiers
     source          1..19969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Ambrose"
                     /db_xref="taxon:1313"
     gene            <1..1422
                     /gene="wzg"
                     /locus_tag="SPC05_0001"
     CDS             <1..1422
                     /gene="wzg"
                     /locus_tag="SPC05_0001"
                     /note="member of homology group 0; DNA sequence does not
                     include 5' end of this CDS"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI32791.1"
                     /db_xref="GOA:Q4K320"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K320"
                     /translation="RSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAFRYLNLVVT
                     ALVLLVTLVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNRLNVTSNYS
                     EYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLTVNQSSSYL
                     AAYKNLIAGETKAIVLNSVFENIIESEYPGYASKIKKIYTKGFTKKVEAPKTSKNQSF
                     NIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKL
                     THAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGIDVYNDQEFTAHTNG
                     KYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTSTEALKNYST
                     IINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSYAIPDSNLY
                     VMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1..93
                     /gene="wzg"
                     /locus_tag="SPC05_0001"
                     /note="Signal peptide predicted for SPC0099 by SignalP 2.0
                     HMM (Signal peptide probability 0.884) with cleavage site
                     probability 0.473 between residues 31 and 32"
     misc_feature    181..528
                     /gene="wzg"
                     /locus_tag="SPC05_0001"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 6.2e-63"
     misc_feature    706..1149
                     /gene="wzg"
                     /locus_tag="SPC05_0001"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 1.8e-69"
     gene            1424..2155
                     /gene="wzh"
                     /locus_tag="SPC05_0002"
     CDS             1424..2155
                     /gene="wzh"
                     /locus_tag="SPC05_0002"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI32792.1"
                     /db_xref="GOA:Q7WVX2"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q7WVX2"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     misc_feature    1427..2035
                     /gene="wzh"
                     /locus_tag="SPC05_0002"
                     /note="HMMPfam hit to PF02811, PHP domain, score 2.3e-38"
     gene            2164..2856
                     /gene="wzd"
                     /locus_tag="SPC05_0003"
     CDS             2164..2856
                     /gene="wzd"
                     /locus_tag="SPC05_0003"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI32793.1"
                     /db_xref="GOA:Q7WVX1"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q7WVX1"
                     /translation="MEKQNTLEIDVLQLFRSLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVSRDQGEKSGLTNQDLQAGSYLTKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVAVPVDTRIVSISVNDQVPEGASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKLNTLIGFLVGLIVINVTVLLLELLDTRVKRPEDIEDALQMT
                     LLGVVPNLDKLK"
     misc_feature    2182..2598
                     /gene="wzd"
                     /locus_tag="SPC05_0003"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 2.9e-50"
     misc_feature    2704..2781
                     /gene="wzd"
                     /locus_tag="SPC05_0003"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            2866..3540
                     /gene="wze"
                     /locus_tag="SPC05_0004"
     CDS             2866..3540
                     /gene="wze"
                     /locus_tag="SPC05_0004"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI32794.1"
                     /db_xref="GOA:Q7WVX0"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q7WVX0"
                     /translation="MPTLEIVQKKLEFIKKTEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSINIAWSFARAGYKTLLIDGDIRNSVMSGVFKSREKITGLTEFLSGTTDL
                     SHGLCDTNIENLFVVQSGAVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGVVI
                     DSAIITQKCDASILVTATGEVNKRDVPKAKQQLEQTGKLFLGVVLNKFNVQHEKYGSY
                     GNYGKR"
     gene            3944..4537
                     /gene="wciI"
                     /locus_tag="SPC05_0005"
     CDS             3944..4537
                     /gene="wciI"
                     /locus_tag="SPC05_0005"
                     /note="member of homology group 29"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32795.1"
                     /db_xref="GOA:Q7WVW9"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW9"
                     /translation="MYSILKRLGDISISLIVITLFCPFFILIAIAIKFDSKGPVIFKQ
                     KRFGIHKKTFYVFKFRTMKVETPKNVATRDLQNPEQWITRVGTFLRKTSLDELPQLCN
                     ILVGDMSIVGPRPALWNQFDLIEERDKYGANDILPGLTGWAQINGRDNLSIDMKAELD
                     GYYVTHKSLLMDIRCIVRTIPYVLKRKGIVEGSQKES"
     misc_feature    3944..4051
                     /gene="wciI"
                     /locus_tag="SPC05_0005"
                     /note="Signal peptide predicted for SPC0103 by SignalP 2.0
                     HMM (Signal peptide probability 0.812) with cleavage site
                     probability 0.384 between residues 36 and 37"
     misc_feature    3959..4513
                     /gene="wciI"
                     /locus_tag="SPC05_0005"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 8.1e-32"
     gene            4546..5772
                     /gene="wciJ"
                     /locus_tag="SPC05_0006"
     CDS             4546..5772
                     /gene="wciJ"
                     /locus_tag="SPC05_0006"
                     /note="member of homology group 35"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32796.1"
                     /db_xref="GOA:Q7WVW8"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW8"
                     /translation="MKILFVSQHYRPEPFRLSDICEDLVERGHEVTVLTGIPNYPEGK
                     TYADYRNNKNRRETIEGVTVFRSYTIPRGKSTLHRILNYFSFAISSSIGVLLGQYKAK
                     DGSEFDCIFVNQSSPVMMAWAAMAYKNKYKKPMFLYCMDVWPDSLTVGGVKQDGLIFK
                     LFKFISKKVYRASDYIFVTSPSFKNYFVNQFDITEQKITYLPQYAEDLFIPDESRVNK
                     ESVDLTFAGNIGKAQNLETILKAASLIEKNTDLPKKIQFHFVGDGTELLSMKALAHEL
                     ELKNVSFYGRRSLEEMPTFYKKSDAMLVSLIGDSIVSRTIPGKVQSYMAAGKPIIGAI
                     SGDTKTIVEEAKCGFVSPEQDVEQLAQNICKFSMLSTEEQRELGKQARCYYGKHFSKE
                     QFMTQLENYLREGFSS"
     misc_feature    5164..5697
                     /gene="wciJ"
                     /locus_tag="SPC05_0006"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1e-12"
     gene            6003..7208
                     /gene="wzy"
                     /locus_tag="SPC05_0007"
     CDS             6003..7208
                     /gene="wzy"
                     /locus_tag="SPC05_0007"
                     /note="member of homology group 217"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI32797.1"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW7"
                     /translation="MESRKKFVCFPNSSLRFYILQAAIALSILSQTPYIWKFSGIPTQ
                     LLIMPLWILLGVVSIFSRIDMERSFLFFLLTIGCLISTIALLDIVTGVSYVFNGLSQQ
                     LYLAVGILVLGYWNADVIVHYWKIITMTFLGACLLISVDIYFHYFQGHTFSNIDYVYR
                     AKNSAASIFLSAVILNLSLYNRKWALWRKVLLLASSGLLIYMCILMRSRAVLLAAAVL
                     PLVYIWFQETSLGHKIGRTLGVSTVVGAFLLNSAIYDFFINNLFLRVTSEYRPSSLTL
                     DYVSSNRFVYFEIFAKEISGHELTGIGYYYMDNFFLESFLNYGYIVGTAFVLIALSPM
                     IYALLQRSSSHRFRMLFLALAFSYTVNALFEGYAPFGPGAKSFILWLVFGCLLNTRIG
                     KVGEHSETS"
     gene            7183..8655
                     /gene="wzx"
                     /locus_tag="SPC05_0008"
     CDS             7183..8655
                     /gene="wzx"
                     /locus_tag="SPC05_0008"
                     /note="member of homology group 7"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI32798.1"
                     /db_xref="GOA:Q4K313"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q4K313"
                     /translation="MVNILKQVSLKWNYVFNLANKLFSLTIPLIVTPYVTRVFSSDHF
                     GIYTYTNTVASYFVTFTLMGISMYGSKKISLKRHDEIAVNDEYASLLTVQLLNVGLAT
                     LTYFLYVTFFVNNNQVIYWIQMLYVISAGFDMTWFLSGLERFREIAVRNIIVNVLSAL
                     MIFFFVHTEADLAIYTLIKVGTIFISQIVIFLPVVRMQRFYLAGAEHIRRTYRGLLLL
                     FIPVLADTLFQTMDKIMLGIYASYTAVGLYYSSRMVTDIPQTVITSLNIILFPRITHL
                     LSQNKKVESNKLFYQSFILIIALSLATAFGVSAIARDFVGIFFGSSYGAVADYVPSLS
                     LYICLAAWSGTIRYQYLIPHSLERVYVVAIILGSGINLVLNSLLIPFLGVYGSILATI
                     ISELVICVYQTYPIRKEIPLKGLLGYVIIFAGLSFLMYLSLGWLRLLLLGRLSTVLLL
                     ASEIIFGILVFTIATITYIYLGNPILWQAIKKYIESRKNV"
     misc_feature    7210..8013
                     /gene="wzx"
                     /locus_tag="SPC05_0008"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.5e-31"
     gene            8652..9533
                     /gene="whaC"
                     /locus_tag="SPC05_0009"
     CDS             8652..9533
                     /gene="whaC"
                     /locus_tag="SPC05_0009"
                     /note="member of homology group 184"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32799.1"
                     /db_xref="GOA:Q4K312"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q4K312"
                     /translation="MISIIMPAYNEEKNIGAAIASIQQQTYTDFQLIIVNDGSTDDTA
                     AIVQEKIMGDERIVFLNPGKIGKVPAYNLASQYVKGDWIYFMGADDQLPLDAFEKWNK
                     EAQKWNPAEKVALRARMRMVSDSHKYDGLVLPKKNTVRNFSGPLTLLSKEMHRFILPI
                     PEAYPNEDIWWGLCIEYFGDRVSLIEDVVVYYRVHEGNSISRTSTFEPFNEKYHIRQI
                     IRRDFLERFSNHLTADQKTKLQRELKLEEARYKGNRLPILLMPGISAVHRLRLLFLSG
                     RRSYVLKVKLDRFFLGH"
     misc_feature    8658..9125
                     /gene="whaC"
                     /locus_tag="SPC05_0009"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 4.3e-28"
     gene            9547..10632
                     /gene="whaD"
                     /locus_tag="SPC05_0010"
     CDS             9547..10632
                     /gene="whaD"
                     /locus_tag="SPC05_0010"
                     /note="member of homology group 185"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32800.1"
                     /db_xref="GOA:Q7WVW4"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW4"
                     /translation="MSKKKISYVTNNIAPFRVMLLDELAKHAEVTLFYVHEIEAGVKA
                     EYVKLRPVRTKLQSITELGLFQTFQMLKEMDMVFFDGYTGWEKMFLMSSMWLTRRQYA
                     ISVDGIINHSNISLKQRLLDFIKSVALSKAEFVLSTNTPTDAYIQQLAPKAKIKRHIF
                     STLSQDDFKNMIEVASDTVFTRYSIRKSEKNLLFVGQFINRKGVDELLAFMKEHEADT
                     SLQLIMVGGTREELSVFETEIPSNIHIIPFLEKTDILELMRVADVFVLPTREDIWGLV
                     IIEALSMGIPIVSTDRCNAALEFVRDGENGYLMQEVTAVELANKLKATFKLDAEHVAR
                     YDQKLMQDYNLEGSAKNIMDILEGIHV"
     misc_feature    10072..10572
                     /gene="whaD"
                     /locus_tag="SPC05_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 3e-22"
     gene            10625..11431
                     /gene="whaE"
                     /locus_tag="SPC05_0011"
     CDS             10625..11431
                     /gene="whaE"
                     /locus_tag="SPC05_0011"
                     /note="previously sequenced as SWALL:Q7WVW3; member of
                     homology group 186"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="CAI32801.1"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW3"
                     /translation="MFNSSCALFIVSCETNQQVVNLLIQSMRQQISHMVSIYVSSDGP
                     LLITDPSVRVLIGQEEVFGDRVATALEQVTEERVIVFCDDFIVEKPAKIEELEELLSL
                     MEEDTSIASIALSQISGGNTPERIAEHYIRRTKYAPYKTTLQCAIWKKSSLIQFMKGS
                     PSPWEFEIYHNFKTYLTKEKFYALEDDMFQPIPYNRGKLIIRGKVVKPEKERLEELLG
                     YSLDLSDFPETESFIQGENLTVGYRLKRKIKLLEKEIIYRLKSKIKNKKK"
     gene            11665..12702
                     /gene="fnlA"
                     /locus_tag="SPC05_0012"
     CDS             11665..12702
                     /gene="fnlA"
                     /locus_tag="SPC05_0012"
                     /note="member of homology group 36"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlA"
                     /protein_id="CAI32802.1"
                     /db_xref="GOA:Q7WVW2"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR013692"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW2"
                     /translation="MFTKKTLLITGGTGSFGNAVLKRFLGTDISEVRIFSRDEKKQDD
                     MRHEFQAKMPEVADKIRFYLGDVRDLASVKNAMIGVDYVFHAAALKQVPSCEFFPVEA
                     VKTNVLGTENILTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAMMEKIAVAKSRTVEE
                     DQTKVCVTRYGNVLCSRGSVIPLWIDQIKQGNPITITEPSMTRFIMSLEEAVDLVLFA
                     FEKGKTGDILVQKAPACTIEVLAQAVTELFAPNQDIKVIGIRHGEKMYETLLTTEECT
                     NAIDLGGFYRVPSDNRDLNYDKYFNEGDAKRNPLIEFNSSNTELWNVEQVKEKLLLLP
                     YIREELASLNQ"
     misc_feature    11680..12516
                     /gene="fnlA"
                     /locus_tag="SPC05_0012"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 0.00038"
     misc_feature    11683..12357
                     /gene="fnlA"
                     /locus_tag="SPC05_0012"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 1.5e-13"
     misc_feature    11683..12531
                     /gene="fnlA"
                     /locus_tag="SPC05_0012"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 5.2e-165"
     misc_feature    11686..12327
                     /gene="fnlA"
                     /locus_tag="SPC05_0012"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 4.4e-08"
     misc_feature    12532..12675
                     /gene="fnlA"
                     /locus_tag="SPC05_0012"
                     /note="HMMPfam hit to PF08485, Polysaccharide biosynthesis
                     protein C, score 1.3e-26"
     gene            12711..13922
                     /gene="ugd"
                     /locus_tag="SPC05_0013"
     CDS             12711..13922
                     /gene="ugd"
                     /locus_tag="SPC05_0013"
                     /note="member of homology group 20"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAI32803.1"
                     /db_xref="GOA:Q7WVW1"
                     /db_xref="HSSP:1DLI"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW1"
                     /translation="MKIAVAGTGYVGLSIAILLAQYHKVIAVDVIPEKVELINRRQSP
                     IKDDDIETYLVEKELDLVATLDGNEAYRDADFVIIAVPTNYDSKKNYFDTSVVEAVIE
                     QIIAVNLKATIVIKSTIPVGYTESLRTRFGQFKILFSPEFLRESKALYDNLYPSRIIV
                     GADLRDTEQVVQAERFATLLQEGSLKPDVETLIMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTKSIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDSKQLLANYHDVPQ
                     NMMTAIVESNRTRKYFIADRILKNALELSDGNQTIIVGVYRLTMKSGSDNFRQSSIQG
                     VIKCLKAKGVEVIIYEPTLEDHSFFFGNQVVNDLEVFKSSSQVIVANRMEKSLYDVLE
                     KVYTRDIFQRD"
     misc_feature    12711..13226
                     /gene="ugd"
                     /locus_tag="SPC05_0013"
                     /note="HMMPfam hit to PF01210, NAD-dependent
                     glycerol-3-phosphate deh, score 0.0013"
     misc_feature    12711..13253
                     /gene="ugd"
                     /locus_tag="SPC05_0013"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 2.1e-52"
     misc_feature    13296..13577
                     /gene="ugd"
                     /locus_tag="SPC05_0013"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 2.6e-36"
     misc_feature    13650..13880
                     /gene="ugd"
                     /locus_tag="SPC05_0013"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 0.00029"
     gene            13941..15170
                     /gene="fnlB"
                     /locus_tag="SPC05_0014"
     CDS             13941..15170
                     /gene="fnlB"
                     /locus_tag="SPC05_0014"
                     /note="member of homology group 37"
                     /codon_start=1
                     /transl_table=11
                     /product="FnlB"
                     /protein_id="CAI32804.1"
                     /db_xref="GOA:Q7WVW0"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR008894"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q7WVW0"
                     /translation="MPLKILVTGSKGFVGKNLICTLEALKDGRDRTRPNLEIGEIFQY
                     DRDTDPILLDEYCKKADFVFHLAGVNRPQNPDEFMEGNYGFSSRLLEILEKYENTCPV
                     LLSSSTQASLEGRFSNSIYGQSKLVGEELFFEYGKKTGAPVLVYRFPNLYGKWCRPNY
                     NSAVATFCHNLAHDLPIQVNDPSVELELLYIDDLIQECLTALEGNPHRCNLDGLQILP
                     SPSGNYCYVPTTHRATLGEIVSLLETFKKQPNSLIMPEIPQGSFKKKLYSTYLSYLPV
                     DKFKFPLKMNIDERGSFTELLKTENKGQFSVNISKPGITKGQHWHHSKWEFFMVVSGR
                     ALIQERRIGLDENGQEYPILNFEVSGDKIEAIHMIPGYAHNIINLSDTENLVTVMWAN
                     ESFDPRHPDTFFEQVEK"
     misc_feature    13953..14576
                     /gene="fnlB"
                     /locus_tag="SPC05_0014"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase fam, score 1.6e-08"
     gene            15171..16355
                     /gene="fnlC"
                     /locus_tag="SPC05_0015"
     CDS             15171..16355
                     /gene="fnlC"
                     /locus_tag="SPC05_0015"
                     /note="member of homology group 38"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-L-fucosamine FnlC"
                     /protein_id="CAI32805.1"
                     /db_xref="GOA:Q7WVV9"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q7WVV9"
                     /translation="MKIKTDYSDIHFKDNGKLKLLIIVGTRPEIIRLSSVITKCRKYF
                     DVILAHTGQNYDYNLNGIFFDNLGLDTPDVYMDAVGDDLGATVGNIINTSYKLMNQIK
                     PDALLILGDTNSCLSAITAKRLHIPIFHMEAGNRCKDECLPEETNRRIVDIISDVNLA
                     YSEHARKYLHECGLPKERTYVTGSPMAEVLHKNLSAIESSDIHERLGLKKGGYILLSA
                     HREENIDTDKNFISLFTAINQLAEKYNMPILYSCHPRSKKRLQESGFKLDKRVIQHEP
                     LGFHDYNCLQMNAFVVVSDSGTLPEESSFFTSQGYPFPAVCIRTSTERPESLDKAGFI
                     LAGIDENSLLQAVETAVSLAEDEDFGLPVPDYVEENVSTKVVKIIQSYTGIVDKIVWR
                     KS"
     misc_feature    15282..16310
                     /gene="fnlC"
                     /locus_tag="SPC05_0015"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 2.6e-103"
     gene            16556..17264
                     /gene="tnp"
                     /locus_tag="SPC05_0016"
                     /pseudo
     CDS             join(16556..16933,16917..17264)
                     /gene="tnp"
                     /locus_tag="SPC05_0016"
                     /note="member of homology group 31"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1671 transposase"
     misc_feature    16935..17261
                     /gene="tnp"
                     /locus_tag="SPC05_0016"
                     /note="HMMPfam hit to PF05717, IS66 Orf2 like protein,
                     score 3.9e-55"
                     /pseudo
     gene            17332..17505
                     /gene="tnp"
                     /locus_tag="SPC05_0017"
                     /pseudo
     CDS             17332..17505
                     /gene="tnp"
                     /locus_tag="SPC05_0017"
                     /note="Lone member of homology group 0218"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative ISPSy5-like transposase (fragment)"
     gene            order(17768..18205,18281..18907)
                     /gene="tnp"
                     /locus_tag="SPC05_0018"
                     /pseudo
     CDS             join(17768..18205,18281..18907)
                     /gene="tnp"
                     /locus_tag="SPC05_0018"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     misc_feature    join(17768..18205,18281..18301)
                     /gene="tnp"
                     /locus_tag="SPC05_0018"
                     /note="HMMPfam hit to PF03050, Transposase IS66 family,
                     score 2.4e-06"
                     /pseudo
     gene            complement(19192..19541)
                     /gene="tnp"
                     /locus_tag="SPC05_0019"
                     /pseudo
     CDS             complement(join(19192..19410,19398..19541))
                     /gene="tnp"
                     /locus_tag="SPC05_0019"
                     /note="member of homology group 219"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1380-Spn1 transposase (fragment)"
     gene            19817..>19969
                     /gene="aliA"
                     /locus_tag="SPC05_0020"
     CDS             19817..>19969
                     /gene="aliA"
                     /locus_tag="SPC05_0020"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI32810.1"
                     /db_xref="UniProtKB/TrEMBL:Q4K305"
                     /translation="MMKSSRLLALAGVTLLTATTLAACSGSGSSTKGEKTFSYIYETD
                     PDNLNYL"
     misc_feature    19817..19903
                     /gene="aliA"
                     /locus_tag="SPC05_0020"
                     /note="Signal peptide predicted for SPC0121 by SignalP 2.0
                     HMM (Signal peptide probability 1.000) with cleavage site
                     probability 0.270 between residues 29 and 30"
BASE COUNT     6201 a   3167 c   4136 g   6465 t
ORIGIN
        1 cgttcacaga aagtgaagcg aagtgttaat atcgttttgc tgactattta tttattgtta
       61 gtttgttttt tattgttctt aatctttaag tacaatatcc ttgcttttag atatcttaat
      121 ctagtggtaa ctgcattagt cctactagtt accttggtag ggctactctt gattatctac
      181 aaaaaagctg aaaaatttac tatttttctg ttggtgttct ctattcttgt cagctctgtg
      241 tcgctctttg cagtacagca gtttgttgga ctgaccaatc gtttaaatgt gacttctaat
      301 tactcagaat attcaatcag tgtcgctgtt ttagcagata gtgagatcga aaatgttacg
      361 caactgacga gtgtgacagc accgactggg actgataatg aaaatattca aaaattacta
      421 gctgatatca agtcaagtca gaataccgat ttgacggtca accagagttc gtcttacttg
      481 gcagcttaca agaatttgat tgcaggggag actaaggcca ttgtcctaaa tagtgtcttt
      541 gaaaacatca tcgagtcaga gtatccaggc tacgcatcga agataaaaaa gatttatacc
      601 aagggattca ctaaaaaagt agaagctcct aagacgtcta agaatcagtc tttcaatatc
      661 tatgttagtg gaattgacac ctatggtcct attagttcgg tgtcgcgatc agatgtcaat
      721 atcctgatga ctgtcaatcg agataccaag aaaatcctct tgaccacaac gccgcgtgat
      781 gcctatgtac caatcgcaga tggtggaaat aatcaaaaag ataaattgac tcatgcgggc
      841 atttatggag ttgattcgtc cattcacacc ttagaaaatc tctatggagt agatatcaat
      901 tactatgtgc gattgaactt cacttcgttt ttgaaaatga ttgatttgtt gggtggaatt
      961 gatgtttata atgatcaaga atttactgcc catacaaatg gaaagtatta ccctgcaggc
     1021 aatgttcatc ttgattcaga acaggctctc ggttttgttc gtgagcgcta ctcactagca
     1081 gatggcgatc gtgaccgtgg gcgcaatcaa caaaaggtga ttgtggctat ccttcaaaaa
     1141 ttaacgtcaa ccgaagcact gaaaaattat agtacgatca ttaatagctt gcaagattct
     1201 atccaaacaa atatgccact tgagaccatg ataaatttgg tcaatgctca gttagaaagt
     1261 ggagggaatt ataaagtaaa ttctcaagat ttaaaaggga caggtcggat ggatcttcct
     1321 tcttatgcaa taccagacag taacctctat gtgatggaaa tagatgatag tagtttagct
     1381 gtagttaaag cagctataca ggatgtgatg gagggtagat gaaatgatag acatccattc
     1441 gcatatcgtt tttgatgtag atgacggtcc caagtcaaga gaggaaagca aggctctctt
     1501 ggcagaagcc tacagacagg gggtgcgaac cattgtctct acctctcacc gtcgcaaggg
     1561 catgtttgaa actccggaag agaagatagc agaaaacttt cttcaagttc gggaaatagc
     1621 taaggaagtg gcgagtgact tagtcattgc ttatggcgca gagatatact atactctgga
     1681 tgctctagaa aagctagaaa aaaaagaaat tcctaccctt aatgatagtc gttatgcttt
     1741 gattgagttt agcatgcata cttcctatcg tcagattcat acgggattga gcaatatttt
     1801 gatgttggga atcacgccag taattgctca tattgaacgg tatgatgctt tagagaataa
     1861 cgaaaaacgt gttcgtgaac tgattgatat gggatgctat actcagataa atagttatca
     1921 tgttttaaaa cctaagttct ttggtgaaaa atataaattc atgaaaaaga gagctcggta
     1981 ttttttggaa cgtgatttag ttcatgtagt tgcaagtgac atgcacaatt tagacagtag
     2041 acctccatat atgcaacagg catatgatat cattgctaag aaatatggag cgaaaaaagc
     2101 gaaagaactt tttgtagata atcccagaaa aattataatg gatcaattaa tttaggagaa
     2161 aatatggaga aacaaaacac tttggaaatc gatgtattgc aactattcag atctttatgg
     2221 aaaagaaagt tggtcatttt attagtggca attataactt cttcagttgc ttttgcctac
     2281 agtacttttg ttatcaaacc tgagtttact agtacgactc ggatttatgt agttagccgt
     2341 gatcagggag agaagtctgg tttaaccaat caagacttgc aggcaggatc gtacttgact
     2401 aaagactatc gtgaaattat cctatcgcag gatgttttgg aggaagttgt ttctgatttg
     2461 aaactagatt tgacgccaaa aggtttggct aataaaatta aagtggcagt accagttgat
     2521 acccgtatcg tgtctatttc ggttaatgat caagttcctg aaggggcaag ccgtatcgct
     2581 aactctttga gagaagtggc ggctcaaaaa attatcagta ttactcgtgt ttctgatgtg
     2641 acaacactgg aggaggcaag accagcgata tcaccgtctt cgccaaatat taaactcaat
     2701 acactaattg gttttttggt aggattgatt gtcataaatg ttacagttct tcttcttgaa
     2761 cttttggaca cacgagtgaa acgtccggaa gatatcgaag atgcactaca gatgacactt
     2821 ttgggggttg taccaaactt ggataagttg aaataggaga gagagatgcc gacattagaa
     2881 atagtacaaa aaaaactgga gttcattaag aagacagagg aatattacaa tgccttgtgt
     2941 acaaacatac agttgagcgg agataaacta aaagtgattt ccgttacttc tgttaaccct
     3001 ggagaaggga aaacaactac ttctataaat atagcatggt cttttgcgcg tgcaggatat
     3061 aaaactcttt tgatagatgg cgatatccga aattcggtga tgtcaggagt ttttaaatct
     3121 cgtgaaaaaa ttacaggctt aacagaattt ttatctggta caactgattt atctcacggt
     3181 ttatgtgata caaatattga aaatttattt gtagttcaat cgggagctgt atcaccaaac
     3241 cctacagcct tgttacaaag taaaaatttt aatgatatga ttgaaacctt gcgtaaatat
     3301 tttgattata tcattgttga tacagcacct attggagttg ttattgattc ggcaattatc
     3361 actcaaaagt gtgatgcgtc tatcttggta acggcaacgg gtgaggtgaa taaacgtgat
     3421 gtcccaaaag cgaaacaaca attagaacaa acagggaaac tatttttagg tgtcgttctc
     3481 aataaattta atgttcaaca tgaaaaatat ggttcttacg gtaattatgg taaaagataa
     3541 aatgaatata gtatggaagg ggctacaata taactctggc attctgaact gcaccccaaa
     3601 agttagacag aaaaaatcta acttttgggg gtcagtacat tcttacaggg tacacttgtt
     3661 agtttattag cttagatact gattgcaatt tcagaaaccg atattttttc aaataaatat
     3721 tcggtctgtt tggaagtgca atcgaactga actttccaat gctttattgg gcatcatata
     3781 ttaccgaaac aaataaattt tgttatattg gatgatgttg ttatgttatt gtaaaaatat
     3841 tgtgtgacca aatatattga gtctttgtgg tctaataggc tgatatattt aatttgataa
     3901 ataaaaataa gatgaagttt gaatttagag tgagagatag tttatgtata gtatattaaa
     3961 acggttagga gatatatcta tatctttaat agttataacg ttattttgtc cattttttat
     4021 cctaattgca attgcgatta agtttgattc aaaaggacct gtaatattta aacaaaaacg
     4081 ttttggaatt cacaaaaaaa ctttttatgt ttttaaattt cggactatga aagtggagac
     4141 accaaaaaat gtggcaactc gagatttaca aaatccagag cagtggatca ctagagtggg
     4201 aactttctta aggaaaacat ctctagatga attgcctcaa ttatgtaata ttcttgttgg
     4261 tgatatgagt attgtaggac caagacctgc cctttggaat caatttgatt tgattgaaga
     4321 aagagacaaa tatggagcaa atgatatttt acctggttta acaggttggg cacaaatcaa
     4381 tggtcgtgat aatctatcaa tagatatgaa agctgaattg gatggatact atgtgacaca
     4441 taaatcgttg ctaatggaca ttagatgtat agtaagaaca ataccttatg tgctgaaacg
     4501 caaaggaatt gtagagggaa gtcaaaaaga gagttaagtt gtacgatgaa aattttattt
     4561 gttagtcaac attatagacc agaacctttt agattatcag atatttgtga ggatcttgtt
     4621 gagagaggtc atgaagttac tgttttgaca ggaattccta attatcctga aggtaaaaca
     4681 tatgcggatt atcggaataa caaaaataga cgagagacta tagaaggagt tactgttttt
     4741 cgttcctata caattccaag gggaaaaagt actttacata ggatattaaa ttattttagt
     4801 tttgctatca gttcctcgat aggggttcta ctgggacagt ataaagcaaa agatggatca
     4861 gaatttgatt gtatttttgt aaatcaatcg tctccagtta tgatggcatg ggctgctatg
     4921 gcttataaaa ataaatataa gaaacctatg tttctgtatt gtatggatgt ttggccagat
     4981 agtttaactg taggtggagt gaaacaagat ggcttgattt tcaagttgtt taaatttata
     5041 tcgaaaaaag tttatcgagc tagtgattat atatttgtta ctagtccatc atttaagaat
     5101 tattttgtga accaatttga cataacagaa caaaagatta cttatttgcc acaatatgca
     5161 gaagatcttt ttatccctga tgaatctaga gttaataaag aaagtgttga cctaactttt
     5221 gctggtaata ttggcaaagc acaaaatttg gaaactattt tgaaagctgc cagtttgata
     5281 gagaagaata ccgatctacc caagaaaatt caatttcatt ttgttggaga tggtacggaa
     5341 ttgctaagta tgaaagcatt agctcatgaa ttggagttaa agaatgtttc cttctatgga
     5401 agacgttctt tggaagaaat gcctaccttc tataaaaaat cagatgctat gttagtttct
     5461 ttaataggag actcgatagt ttctcgtact atacctggga aggtacaatc ttacatggcg
     5521 gcagggaaac caattatagg tgcaatttca ggagatacta aaacaattgt agaagaagca
     5581 aagtgtggtt ttgtcagtcc tgaacaagat gtggaacaat tggcacaaaa tatttgtaaa
     5641 tttagtatgt tgtctacgga agaacaaaga gagttaggaa agcaagctcg ttgttactat
     5701 gggaagcact tttctaaaga gcagtttatg acacagttag aaaattattt gagagagggc
     5761 ttttcctcat gagaatttta atgattaata ctgtttgtgg tattaggagt atagatactt
     5821 tgttaaagaa atttgctgag atttggcgtt tcaatttata ggatttgaaa gtttagtaag
     5881 taaatttaag tattttctgt aagataataa gttcttaatg acttattaac tattgtataa
     5941 tagctgtaat tccaaataaa agtacatagg tactgacatg ttgacgatag taaggaggag
     6001 gaatggaatc ccgaaagaaa tttgtttgtt ttcccaatag tagtttgcgt ttttatattt
     6061 tgcaggcagc gattgcctta tctattttat cgcagactcc ctatatctgg aagtttagtg
     6121 ggatacctac acaacttctg attatgcctt tgtggatcct gttgggagta gtgtctattt
     6181 tttctagaat tgacatggaa cgatcattcc tatttttttt attaacaata ggttgtttaa
     6241 ttagcactat tgctttgtta gatatagtta cgggagtatc ttatgtcttt aatggtttgt
     6301 ctcagcaact ctatttggct gtgggaattc tagttttagg ctactggaat gctgatgtga
     6361 ttgttcatta ttggaaaatc atcaccatga cttttttggg agcatgtttg ctgatttcag
     6421 tggatattta ttttcactac tttcaaggac atactttttc aaatattgat tatgtttatc
     6481 gagctaagaa ttcagcggca tctatctttt tatcggcagt tattctcaac ttgtctctat
     6541 ataatcgcaa gtgggcactg tggagaaaag tattgttatt agctagtagc ggattgctga
     6601 tttacatgtg catccttatg cggtcacgag cagttctgtt agcagctgca gtacttccgc
     6661 tagtttatat atggtttcag gagacgtctt tggggcataa gattggacgg acattaggag
     6721 tttcaacagt agtaggtgcg tttttgctca attcagctat ttatgatttt tttatcaata
     6781 atctattttt aagggtcaca tctgaatatc gaccatctag tctgactttg gactacgttt
     6841 cctccaaccg ttttgtgtat tttgagatct ttgctaaaga aatttcagga catgaattaa
     6901 cagggattgg ttattattat atggataatt tttttctaga gagttttctc aattatggtt
     6961 atatagtagg gactgctttt gttttaatag ccttgtctcc catgatttat gccctcttgc
     7021 aacgttcttc ttctcatcgt ttccgcatgc tttttttagc ccttgctttt tcttatactg
     7081 tcaatgcctt atttgaaggt tacgcgccat ttggtcctgg tgccaagagt tttattcttt
     7141 ggttagtttt tggttgcctt ctgaatacac gaattggaaa ggttggtgaa cattctgaaa
     7201 caagttagtc taaagtggaa ctatgtgttt aatcttgcca ataaactatt ttctctaact
     7261 attccactta ttgttactcc ctatgtcact cgagtctttt cttcagatca ttttgggatt
     7321 tatacttata ccaatacagt tgcttcttac tttgttacct ttacattgat ggggataagt
     7381 atgtatggaa gtaagaaaat ttctcttaaa agacatgatg agatagcagt caatgatgaa
     7441 tatgcttcct tactgactgt ccagctgctt aatgtaggtc tagccacgtt aacttacttt
     7501 ctctatgtga ccttttttgt caataataat caagttattt attggatcca gatgttgtat
     7561 gtgatttctg ctggttttga tatgacttgg tttttatcag gattggaacg ttttcgtgaa
     7621 attgctgttc gaaatatcat tgtaaatgtc ttatcagccc tcatgatttt tttctttgtg
     7681 catacggagg ctgatttggc tatctatacc ttaataaagg tagggacgat ttttatcagt
     7741 cagattgtta tttttttacc agttgttcgg atgcaacggt tttatcttgc aggagctgaa
     7801 catattcgac gtacctatcg aggcttgctt ttgttgttta tccctgtttt ggcagacacc
     7861 ctttttcaaa ctatggataa gatcatgcta ggtatctatg catcctatac tgctgtgggt
     7921 ttgtattact caagtaggat ggttactgac atcccgcaaa ctgtcattac ttctctcaat
     7981 ataatcttat ttccacgaat aacacatctt ttaagtcaga ataaaaaagt tgaatctaat
     8041 aaactttttt atcagtcttt tatcttaatt attgctttat ctctagctac agcttttgga
     8101 gttagtgcta ttgctaggga ttttgtaggt attttttttg gatcttcata tggtgcggta
     8161 gcagattatg tgcctagttt atcgctctat atctgccttg ctgcctggag tggaacgata
     8221 cgttaccaat atctgattcc tcattcactt gagagagtct atgtagtagc gattattttg
     8281 ggaagtggga tcaatctagt tttaaactct ctcttaattc cttttttggg agtatacggt
     8341 tccattttag ctactattat atcagaatta gtgatttgtg tttaccagac atatcctatt
     8401 cgaaaggaaa ttcctcttaa aggattgtta ggatatgtga tcatttttgc aggcttgtct
     8461 tttcttatgt atctatctct tggttggcta cgattgttat tgctaggccg cctatccaca
     8521 gtattgctat tggcaagtga aataatattt ggtatccttg tttttactat cgcaactata
     8581 acctatattt atctaggtaa cccaatttta tggcaagcta ttaaaaaata tatagaaagt
     8641 aggaaaaacg tatgatctct atcattatgc cagcttataa tgaagaaaaa aatatcggag
     8701 cagctattgc cagtattcaa cagcaaacct atacggactt tcagttgatt atcgtcaatg
     8761 atggatctac agatgatacg gcagctattg tacaggaaaa aatcatggga gatgagcgaa
     8821 ttgtcttttt gaatcctgga aagattggca aggtaccagc ttataacttg gcttcacagt
     8881 atgtaaaagg agactggata tattttatgg gagcggatga ccagttgcca ttggatgcct
     8941 ttgaaaagtg gaacaaggag gctcaaaagt ggaatcctgc tgaaaaggtg gctttaagag
     9001 ctcgcatgcg gatggtttct gactctcaca agtatgatgg attggtatta ccaaagaaaa
     9061 atacagttcg caattttagt ggacctctta ccttgctttc aaaagagatg caccgtttta
     9121 tccttcctat acctgaggcc tatccgaacg aagatatttg gtgggggcta tgtattgagt
     9181 atttcggaga tcgtgtttcg ttgattgagg atgttgtggt ttattatcgt gttcatgagg
     9241 ggaattctat atcccgaacc tcaacttttg aaccttttaa cgagaaatat catatccgtc
     9301 agattatccg tcgtgatttt ttagagagat ttagcaatca cttaacagca gaccagaaga
     9361 ctaaacttca gcgtgaattg aaactagaag aagcacgcta taaaggaaat agattgccaa
     9421 ttcttctgat gccaggtatt tctgcagtac acagacttcg attacttttt ttatcgggta
     9481 ggcgttcata tgtacttaaa gtcaaattgg atcgcttttt cttaggacat tagaaagaag
     9541 gaagagatgt caaagaaaaa aatttcttat gttacaaata atattgctcc ttttagggtt
     9601 atgttattag atgagttagc caagcatgca gaagtgactc ttttttatgt gcacgaaatt
     9661 gaggcggggg taaaggctga gtatgtcaag ctacgacctg ttcgtaccaa gctccaatca
     9721 atcacagaac taggtttatt tcagacgttt caaatgttga aagagatgga tatggtcttc
     9781 tttgatggct atactgggtg ggaaaagatg ttcttgatga gcagtatgtg gctaacaaga
     9841 cggcagtacg ctatttctgt tgatggtata ataaatcata gtaatatctc acttaagcag
     9901 agactgttgg attttattaa gtctgttgct ctaagcaaag cggagtttgt gcttagcacc
     9961 aataccccaa cagatgctta tatacagcaa ttagctccca aggcaaagat taaacgacac
    10021 atattttcaa ctctttcaca agatgatttc aaaaacatga tagaggttgc ctcggatacg
    10081 gttttcacaa gatatagtat tcgaaaatct gagaaaaatc tgctttttgt gggacagttt
    10141 atcaatagaa aaggagtcga tgagcttttg gcttttatga aagagcacga agctgatact
    10201 tcgttgcagt taattatggt cggaggtaca agagaagaat tgtcagtttt tgaaacagag
    10261 attccttcta atatacatat aattcctttt ctagaaaaaa ctgatatcct agagttgatg
    10321 cgggtggcag atgtctttgt tttgcccact cgagaagata tttggggact ggttattata
    10381 gaggcgctat caatgggcat tcctattgtt tctacggatc gttgtaacgc agccttggag
    10441 tttgttaggg atggcgaaaa tggttatctg atgcaggaag tgactgcggt agaattggct
    10501 aacaagctta aggctacctt taaactagat gctgagcatg ttgctcgcta tgatcaaaaa
    10561 ctgatgcaag actataatct ggaaggttca gcaaaaaata ttatggacat cttggaggga
    10621 attcatgttt aattcatctt gtgctttatt tattgttagt tgcgagacta atcagcaggt
    10681 agtcaatctc ctcatccagt ccatgcgtca gcagatttct catatggtat ccatttatgt
    10741 atcatcagat ggcccattgt taatcacgga tcctagcgta agggttttga ttggtcagga
    10801 agaagttttt ggagatcgtg ttgcaactgc tttggaacaa gttactgaag agcgagtcat
    10861 tgttttttgt gatgacttta tcgtagaaaa accagctaaa attgaagaat tagaagaact
    10921 actgtctcta atggaagagg atacaagtat tgctagtatt gccctgtcac aaatatctgg
    10981 agggaataca cctgagcgta ttgctgagca ttatataaga cgcacgaaat atgcccccta
    11041 taagacaact cttcaatgcg ctatttggaa gaagtctagt ttgattcaat tcatgaaggg
    11101 gagtccctct ccttgggaat ttgagattta tcataacttt aaaacttacc tgacgaaaga
    11161 gaaattttat gctttagagg atgatatgtt ccaacctatc ccttataata gaggaaagtt
    11221 gattattcga ggtaaagttg ttaaacctga aaaagaacgt ttggaggaac ttttgggtta
    11281 ttcattagat ttatcggatt tcccagaaac ggagtctttt atccaggggg aaaatcttac
    11341 tgtaggctat cggttgaaga gaaagattaa attgttagaa aaagaaatta tttatcgttt
    11401 gaaatctaaa ataaagaata agaaaaaata gtgaaaaaga aagtttataa tatttggtgg
    11461 atgcaaaaga tttaaagatt gagttatctt tatttctaca cctttaaaaa atatagcttt
    11521 tcttttggat aaggtgtatg ttgaaattct caccaatatt atcagtcaga aaaatattgt
    11581 agtgcgttat ttttcatgtt gttaagcttt aaatttattt aaaaagcatt atgttgaaca
    11641 tcattataga taggagtaat aactatgttt acaaagaaaa ctctccttat tacagggggg
    11701 acaggttcat tcgggaatgc agttctcaaa cgatttttgg gaacagatat ttcggaggta
    11761 cgtatctttt caagagatga gaagaaacag gatgatatgc gtcatgaatt tcaagcaaaa
    11821 atgccagaag tagctgataa gatacgtttt tacttaggag atgtgcgtga tttagcttct
    11881 gttaaaaatg ctatgatcgg tgtggattac gtatttcatg ctgctgcatt aaaacaagtc
    11941 ccttcttgtg aatttttccc tgtggaagca gtcaaaacta acgttctagg aactgaaaat
    12001 attctcactg cagctataga agctggagta aaacaagtca tctgcctttc tacagataag
    12061 gcagcctatc ctgttaatgc gatgggaacc tctaaggcta tgatggaaaa gattgctgtt
    12121 gctaagtcaa ggacggtaga agaagatcag acaaaagtct gtgtaactcg ctacggcaat
    12181 gttctatgta gtcgtggttc tgtgattccc ctatggattg atcaaataaa gcaagggaat
    12241 cctataacga ttacggaacc tagtatgact cgttttatta tgtccttaga agaagcggta
    12301 gacctagttc tgtttgcttt tgaaaaagga aaaacaggag atatcctagt acagaaagca
    12361 ccagcatgta ccattgaagt gttggcgcaa gctgttacgg aactttttgc acctaatcaa
    12421 gatattaaag taatcgggat tcgccacggt gaaaagatgt atgaaacgtt gttgactact
    12481 gaagaatgta cgaatgccat tgatttaggc ggcttttatc gtgtgcctag cgataatcga
    12541 gatcttaact atgataagta tttcaacgaa ggggatgcca aacgcaatcc cttaatagag
    12601 tttaacagta gtaatacaga actctggaat gtcgagcagg ttaaggaaaa actcttactt
    12661 ttgccctata ttagggaaga attagcatct ttaaatcagt gaggtatcct atgaaaatag
    12721 cagtagcagg gacaggttat gtgggtttat ctattgcaat tctattagcg caatatcata
    12781 aggttatagc ggtagatgtt attcctgaaa aagtagagct tatcaatcgt cgccaatctc
    12841 ccattaagga tgatgatatt gaaacttatt tagtggaaaa ggaattagac ttagttgcaa
    12901 cattagatgg taatgaagct tatcgagatg ctgactttgt cataattgct gtcccaacta
    12961 actatgacag taaaaaaaat tattttgata catctgttgt ggaagcagtt attgagcaga
    13021 ttattgcggt taatttgaag gcaacaattg tcataaaatc cacaattcct gtgggatata
    13081 cagaaagtct ccgaacacgt tttgggcaat ttaagattct ctttagtcct gaatttttac
    13141 gggagtctaa agcactttat gataatctct atcctagtcg aatcatcgtt ggagcagatt
    13201 tgagagatac ggagcaggta gttcaggctg agcggtttgc aactcttttg caggaaggtt
    13261 cacttaaacc tgatgttgag accttaatta tgggtgtaac agaggcagaa gcagtcaaac
    13321 tatttgccaa cacctatttg gctttgcggg tttcttactt taacgaattg gatacctatg
    13381 cggagataaa gggattggac actaaatcca tcattgacgg agtagggtta gatccacgaa
    13441 ttggtagcca ttataacaat ccgtcatttg gttatggagg ttattgtctt cccaaagata
    13501 gtaagcagtt gctggcgaat tatcatgatg taccacaaaa tatgatgaca gctattgtag
    13561 aaagtaaccg tactcgcaag tattttattg ccgatcgtat tttgaaaaat gcgttggagc
    13621 tttcagacgg taatcaaaca atcatagtag gtgtttaccg cttaactatg aagagtggtt
    13681 cggataattt ccgtcaatca tcaatccaag gtgttataaa atgtttaaag gccaaaggtg
    13741 tagaagtaat tatctatgaa ccaactttgg aggatcatag ctttttcttt ggtaatcagg
    13801 tggttaatga tttggaagtt tttaagtcta gcagtcaagt gattgttgcc aatcggatgg
    13861 aaaaatcttt atatgatgtg ctagaaaaag tttatacaag agatattttt cagcgagatt
    13921 aagtatatgg agggaaaaat atgccattaa aaattttagt gactggttct aaaggatttg
    13981 taggaaaaaa tcttatctgt actctggaag ctttgaaaga tggacgagat aggactcgtc
    14041 ctaatttaga gattggagag atttttcagt atgatcgtga tacagatccg attttattag
    14101 atgaatattg taagaaggcc gatttcgtat tccatttagc tggtgtcaat cgtccacaga
    14161 atcctgatga attcatggag ggaaattacg gtttttcaag tagattattg gagattttag
    14221 aaaagtatga aaacacttgt cctgttctac tctcaagttc tactcaagct agtttagaag
    14281 gccgattttc aaactctata tatggacaat ctaagctagt aggggaagaa ctcttctttg
    14341 aatatggaaa gaaaacggga gcacctgtct tagtttaccg tttcccgaat ctttatggga
    14401 agtggtgccg tcctaactac aattctgctg tagcaacttt ctgtcataat ctagctcacg
    14461 atttacctat tcaagtaaat gatccaagtg tagaattgga gttgctgtat attgatgatt
    14521 tgatacaaga gtgtctaact gcattggaag gaaatcctca tcgttgtaat ctagatggat
    14581 tacaaatctt acctagccca tcaggaaact actgctacgt accaacgact catcgtgcaa
    14641 ccttaggaga gattgtctct ctattagaaa catttaaaaa acagcctaat agtttaatta
    14701 tgcctgaaat tcctcaagga tcgtttaaaa agaaattgta ttctacctac ctatcttatt
    14761 taccagtaga taagtttaag tttcctctaa aaatgaatat agatgaacga ggtagtttta
    14821 cggaattatt aaaaacagaa aataagggtc aattttctgt taatatttct aaacctggca
    14881 ttaccaaagg gcaacattgg catcattcta agtgggaatt tttcatggtt gtttctggtc
    14941 gtgctttaat acaagagcgt aggatagggc tggatgaaaa cggtcaagag tatcctattc
    15001 tgaactttga agtgtcgggc gataagattg aagcaataca tatgataccg ggctatgcac
    15061 ataatattat taatctttct gatacagaaa atctagttac tgtcatgtgg gctaatgagt
    15121 catttgatcc tagacatcca gatacttttt ttgaacaagt ggagaaataa atgaaaatta
    15181 agacagatta tagtgatatt cactttaaag ataatggcaa acttaagtta ttgattattg
    15241 tgggaacacg tccagagatt atacgtctaa gtagtgttat cactaaatgt cgaaagtatt
    15301 ttgatgttat tttggcacat actggacaaa actatgatta caatttaaat ggtattttct
    15361 ttgataattt agggttagac actccggatg tatacatgga tgctgttgga gatgatcttg
    15421 gtgctactgt agggaatatt attaatactt catacaaatt gatgaatcaa attaaaccag
    15481 atgctttatt gattttaggg gatacaaatt cttgtttatc agctattact gccaagcgtt
    15541 tacatattcc aatttttcat atggaggctg gcaatcgctg taaggatgag tgcctgccgg
    15601 aagagactaa tcgtcggatt gttgatatta tttcagatgt taacttagca tactctgaac
    15661 atgcacgtaa gtatttacat gagtgtggtt tacctaaaga gcgcacatat gtaacaggtt
    15721 ctcctatggc agaagtgtta cataaaaatt tatctgccat tgagtcttca gatatccatg
    15781 aacgtttggg attgaaaaaa ggaggttata tcttactttc agctcaccgt gaggaaaata
    15841 ttgatacaga taaaaatttt atttctctct ttacagcaat taatcaatta gctgaaaagt
    15901 ataatatgcc aatcttatat tcttgccatc ctagatcaaa gaaaaggcta caagagagcg
    15961 gttttaaact agataaacgt gtgattcagc atgagccact aggattccat gactataatt
    16021 gtttacagat gaatgcattt gttgtagtat ctgattcggg aactttaccg gaagaaagta
    16081 gtttctttac tagtcaaggt tatccttttc ctgctgtatg tattcgtaca agtacagaac
    16141 gtcctgagtc cttagataag gcaggattta ttttggcagg cattgatgaa aattctcttc
    16201 ttcaagcagt tgaaactgct gttagcttgg cagaagatga ggattttgga ttaccggttc
    16261 cagattatgt tgaggaaaat gtctctacta aagttgttaa gataatacag agctatacag
    16321 ggatagtgga taaaatagtt tggaggaaaa gctgaattgt atatttttaa taaatcaaaa
    16381 cgagatgatt aattcttagt agaacaagag taaaattgaa cgtatttgat ggaaatgtct
    16441 tacttgatag tcgagggata gccattctat cggatttttg gcttgttttt gcgcttcatg
    16501 tttgatagaa taaagggctc tttgttaact gtagtgggtt gaagaaaagc taagcttgag
    16561 aaaggacaaa tttcgtcctt tcttttttga tgttcagagc gatgaaaatc cgttttttga
    16621 agttttcaaa gttccgaaaa ccaaaggcat tgcgcttgat aagtgtaagc gcgtcataac
    16681 aaggtatcta tcattcatgg agctcctcct gtatactatt agtaaagtaa aactattgga
    16741 ggatatttta atgccacaac ctattgttcc tgtagagatt ccacaatctc gtcgttttga
    16801 ttctaaaaag agaaatgata ttctacttaa aattcgtatt ggcaagcttg aagtaagttt
    16861 ttttcaatct ctcaatctcg aaatgataga acagcttttg gataaggtgt tgctctatga
    16921 caattcatct atctagccta gggcaggtct atctcgtatg tgggaaaacg gatatgaggc
    16981 aaggcattga ttcactggct tatctggtta aaacccactt tgaattagat cctttctcag
    17041 gtcaagtttt tctcttttgt ggtggacgta aagaccgctt taaagccctt tactgggatg
    17101 gtcaaggatt ttggctacta tataaacgct ttgagaacgg cagactgact tggcccagta
    17161 cagaaaagga tgtcaaagct ctcacacctg aacaagtaga ctggcttatg aagagctttt
    17221 ctatcactcc caaaataaac tcatcagaaa gtcgtgattt ctattgaaat gaggactttc
    17281 tttttagtat aataaagtta gaaaacagag agggaagctc atggaagaag attgaaaatc
    17341 attcaacaac agagtgctac aattgatagt ctcaccaatg aacttgccct tcttcgtgaa
    17401 caagtggctt atctgactca aaagctctat ggaaaatcct ctgagaaaag tgtttgcccc
    17461 tctggacaac tcaacctttt tgaggaagat ggagatgttc ccagttgaaa cagaggaaat
    17521 tacccacaaa cgtaagaaat ctaaagggaa acgccaagct cttcttgccc aatttgattc
    17581 agaagaagtt catcatcaag tagaagagag catttgccct gattgtcagg gagatctaaa
    17641 agagattgga gcaacccttc aacgacaaga attagtcttt attcctgcgc aattaaaacg
    17701 aatagatcat atccaacacg cttataagtg ccaagcatgc agtgataaaa atccgagtga
    17761 taaaatcgtg aaagctccta ttcctaaagc ccctttggcg catagctttg gctcagcttc
    17821 tattatcgct cacaccatcc atcagaagtt taatctgaag gtacccaatt atcgccaaga
    17881 agaagattgg gctaggatgg gtttaccaat cacacgtaag gaaatctcta attggcatat
    17941 caaggcaagt caatactatt tagagtccct ttataacctt ttacgagaaa agttgttaga
    18001 acaacctctt cttcatgcgg atgaaacctc ctatcgggtt ctagagagtg atagtcagct
    18061 gacttactat tggacttttt tgtcaggtaa agctgagaat caagcaatca cgctgtacca
    18121 ccatgatcag cgtcggagtg gttcggtagt gcaagaattc ctaggaaatt attctggcta
    18181 tgtgcattgt gatatgttgc ggcagtaact taggacttta gtcctctagt tctgcctatg
    18241 cgatagcagt ccaaggttta ggagcaaggc gacgctaagc ttggtaaact gcgaaccgct
    18301 agaagcttat cgtcaactgg aagaagctga acttgttgga tgttgggcgc atgtgagaag
    18361 gaaatttttt gaagcgcccc ccaagcaagc ggataaatca tcgttaggag ctaaaggttt
    18421 agcttattgt gatcagttat tttccttgga aagagactgg gaggctttgc cagctgatga
    18481 acgactacag aaacgtcaag aacatctcca acccctactg gaagacttct ttgcttggtg
    18541 ccgtcgtcag tcagttttat cgggttcaaa actaggaagg gcaattgaat acagcctcaa
    18601 gtatgaagaa acctttaaga ccattttaaa agacggacat ctggtccttt ccaataatct
    18661 agctgaacgc gccattaaat cattggttat gggacgtaaa aattggttgt tttctcaaag
    18721 ttttgaagga gctaaagcaa gagctattat tatgagctta ttggaaacag ctaaacgtca
    18781 tcaactaaat agtgagaaat atctatccta tcttccagaa tgtcttccaa acgaggaaac
    18841 tctcgtaaac aaagaggttt tagaggccta tttaccgtgg actaaagttg tacaagaaaa
    18901 gtgcaaataa gaaatctcca gattaggaac tatatatgag ttctctagtc tggagatttt
    18961 tcaatatact tcgttattgg gcggttacga tattcaaccc aaatcattca tacccctctc
    19021 aactagatgt aacttacaaa acccctgacc tcatgagcca ctttcttcct cctcatgagg
    19081 tcagttttac tttctgctgt tccagtatcg tttttcctcg ctagatttcc tcaaaagggc
    19141 agacttctcc cttggtgcat cacacgattt tttcatctcg actgttcttt aatgcatcat
    19201 taacgacgct tttcttccag gtggttcata aggaacagga agattcaggt tgacttttct
    19261 aatcctagaa taaagtgctg aaaacaattc ggaataggca tagagactag acaatttgag
    19321 gagctgcttg cgtcctgttc gaacacattt tcctaccacg tgaagaaaaa gatggcggaa
    19381 gcgtttgatt gttaaagttt ggaagtcacc tcttttagtt tcaactggga aaaaagttcc
    19441 tgaaaaaaga taagaccacc atactgggtt aaatgacctc catcgaaaga tagttggtaa
    19501 aaagacttgt tttggaagtg atgatttggt aaactgttca tgtgagtttc ctttcttttt
    19561 gtgttttttt ctacacttat accataaagg ggaaactctt ttttgtctag taaaaaacac
    19621 ccattgggtg aaaaaagaaa ccatccagga tctaagctaa ggcaaggatt ctggatggtt
    19681 tttagattag gggtgaataa ttggggatat tttttgaaaa gatgttgttt gaaaaataat
    19741 tttcaaaaat tctgaaaatt ctgttgacat ctttctgaaa agagtttata atggagagaa
    19801 agttttaaag gagaaaatga tgaaaagttc aagactactt gcccttgcgg gcgtgacatt
    19861 attgacggcg actactttag ctgcatgctc tggatcaggt tcaagcacta aaggtgagaa
    19921 gacattctca tacatttatg agacagaccc tgataacctc aactatttg
//
