LOCUS       CR931638               17611 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain 34351= Rodriques (serotype 6a).
ACCESSION   CR931638
VERSION     CR931638.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17611)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 17611)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..17611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="34351=Rodriques"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC06A_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC06A_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI32811.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..458
                     /gene="aliB"
                     /locus_tag="SPC06A_0002"
                     /pseudo
     CDS             293..458
                     /gene="aliB"
                     /locus_tag="SPC06A_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(459..981)
                     /gene="tnp"
                     /locus_tag="SPC06A_0003"
                     /pseudo
     CDS             complement(join(459..521,520..981))
                     /gene="tnp"
                     /locus_tag="SPC06A_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase (fragment)"
     gene            1309..2754
                     /gene="wzg"
                     /locus_tag="SPC06A_0004"
     CDS             1309..2754
                     /gene="wzg"
                     /locus_tag="SPC06A_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI32814.1"
                     /db_xref="GOA:Q4K303"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q4K303"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSTLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIKKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1309..1425
                     /gene="wzg"
                     /locus_tag="SPC06A_0004"
                     /note="Signal peptide predicted for SPC0126 by SignalP 2.0
                     HMM (Signal peptide probability 0.997) with cleavage site
                     probability 0.540 between residues 39 and 40"
     misc_feature    1513..1860
                     /gene="wzg"
                     /locus_tag="SPC06A_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 9.8e-65"
     misc_feature    2038..2481
                     /gene="wzg"
                     /locus_tag="SPC06A_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 6.5e-70"
     gene            2756..3487
                     /gene="wzh"
                     /locus_tag="SPC06A_0005"
     CDS             2756..3487
                     /gene="wzh"
                     /locus_tag="SPC06A_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI32815.1"
                     /db_xref="GOA:Q4K302"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q4K302"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQNLVYVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     misc_feature    2759..3367
                     /gene="wzh"
                     /locus_tag="SPC06A_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 2.1e-38"
     gene            3493..4188
                     /gene="wzd"
                     /locus_tag="SPC06A_0006"
     CDS             3493..4188
                     /gene="wzd"
                     /locus_tag="SPC06A_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI32816.1"
                     /db_xref="GOA:Q9AHB8"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q9AHB8"
                     /translation="MMKEQNTIEIDVFQLFKTLWQRKLMILLVALVTSAGAFAYSTFI
                     VKPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDALEKVATNLKL
                     DMPAKTLASKVQVAVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDIEDVLKI
                     PLLGLVPDFDKMK"
     misc_feature    3514..3930
                     /gene="wzd"
                     /locus_tag="SPC06A_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1.1e-53"
     misc_feature    4036..4113
                     /gene="wzd"
                     /locus_tag="SPC06A_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4198..4887
                     /gene="wze"
                     /locus_tag="SPC06A_0007"
     CDS             4198..4887
                     /gene="wze"
                     /locus_tag="SPC06A_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI32817.1"
                     /db_xref="GOA:Q9AHB7"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q9AHB7"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            4902..6269
                     /gene="wchA"
                     /locus_tag="SPC06A_0008"
     CDS             4902..6269
                     /gene="wchA"
                     /locus_tag="SPC06A_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32818.1"
                     /db_xref="GOA:Q4K2Y3"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q4K2Y3"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYINGWTIWKDIEILLKTVKVVFM
                     RDGAK"
     misc_feature    4902..4988
                     /gene="wchA"
                     /locus_tag="SPC06A_0008"
                     /note="Signal peptide predicted for SPC0130 by SignalP 2.0
                     HMM (Signal peptide probability 0.759) with cleavage site
                     probability 0.388 between residues 29 and 30"
     misc_feature    5685..6266
                     /gene="wchA"
                     /locus_tag="SPC06A_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 1.7e-160"
     gene            6365..7309
                     /gene="wciN"
                     /locus_tag="SPC06A_0009"
     CDS             6365..7309
                     /gene="wciN"
                     /locus_tag="SPC06A_0009"
                     /note="member of homology group 62"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32819.1"
                     /db_xref="GOA:Q9AHB5"
                     /db_xref="InterPro:IPR002495"
                     /db_xref="UniProtKB/TrEMBL:Q9AHB5"
                     /translation="MNIVYATDNNFVDVLSASIKSLYTTNSDLDLNLWIIADKVSDRN
                     KEKINRLSKQFAQREINWIENVEIPFKLHLDRGSISSFSRLFLGSVLPSSMSKVLYLD
                     SDIIVMDSLRSIFDIDFKGKILYGVNDTFNKEYKQVLGIPIDKPMFNAGVMLINLELW
                     RNNNVEERFLQVIQKFNGTILQGDLGVLNAVLYNSFGVLPPEYNYMTIFEDLTYEEMI
                     VFKKPINYYSKEEIKNARERIVLRHFTTSFLSKRPWQEGSNVAHIDQFKKYYEGSYKN
                     VKESILLKIVQKLPKKCSVFLLGIIQSKFRPKLYRILK"
     misc_feature    6368..7138
                     /gene="wciN"
                     /locus_tag="SPC06A_0009"
                     /note="HMMPfam hit to PF01501, Glycosyl transferase
                     family, score 3.9e-72"
     gene            order(7347..7490,7492..7593)
                     /gene="HG262"
                     /locus_tag="SPC06A_0010"
                     /pseudo
     CDS             join(7347..7490,7492..7593)
                     /gene="HG262"
                     /locus_tag="SPC06A_0010"
                     /note="member of homology group 262"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative LicD-family phosphotransferase
                     (pseudogene)"
                     /db_xref="PSEUDO:CAI32820.1"
     gene            7580..8299
                     /gene="wciO"
                     /locus_tag="SPC06A_0011"
     CDS             7580..8299
                     /gene="wciO"
                     /locus_tag="SPC06A_0011"
                     /note="member of homology group 81"
                     /codon_start=1
                     /transl_table=11
                     /product="putative ribitol phophotransferase"
                     /protein_id="CAI32821.1"
                     /db_xref="GOA:Q4K2Y1"
                     /db_xref="InterPro:IPR000462"
                     /db_xref="UniProtKB/TrEMBL:Q4K2Y1"
                     /translation="MSIYRICKDIERKTMSPAKKAMAKNDYFAFYVGRPLSYLLTVPF
                     VKTNITPNQISYLSIIPLIVGFIIMIFTTDFVVLLLAWFLFFLWNLLDGVDGNLARYR
                     EQYSKDGSVVDAMAGYVAMVLTYFGAGIVAAHLNDSDIYIILGALSGISLIFPRLVMH
                     KYINTVAQDESVSSIKDKSDFNTIKILALNMTSITGIPQVLLLLTILTNQWVLFTLVY
                     FTINFLLMIFSLYSLFKKENV"
     misc_feature    7823..8287
                     /gene="wciO"
                     /locus_tag="SPC06A_0011"
                     /note="HMMPfam hit to PF01066, CDP-alcohol
                     phosphatidyltransferase, score 0.01"
     gene            8302..9288
                     /gene="wciP"
                     /locus_tag="SPC06A_0012"
     CDS             8302..9288
                     /gene="wciP"
                     /locus_tag="SPC06A_0012"
                     /note="member of homology group 97"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32822.1"
                     /db_xref="GOA:Q8RIW1"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q8RIW1"
                     /translation="MGKSVAILMTTYNGERYLSQQIDSIRSQTFTNWTLFIRDDGSKD
                     KTIEVIQRYSKIDDRIRFVENPSKFHGAYYNFFNLIEYVKNNYQFDYYFFCDQDDIWK
                     EHKLEIQLLRFSKDDMPEMVYSDMSMIDASNNLIDISINKIMGIELPNINNLYFIHAY
                     IWGCTAGFNHALLEMVPSVDIDKDYLYIEKLAHDSYFAKFALEYGKVLFCPEQLVLYR
                     RHGHNVTTSHHFKLSPLNVFRKAILGFNELALTHARVYNQTLYMLKKASGKNPLSDRL
                     LEIQEVIKIGGLKGVRYFYQNRISRKQLVRTIGLYTIMLFGTYKKYIMKELL"
     misc_feature    8317..8820
                     /gene="wciP"
                     /locus_tag="SPC06A_0012"
                     /note="HMMPfam hit to PF00535, Glycosyl transferase
                     family, score 7.7e-25"
     gene            9288..10631
                     /gene="wzy"
                     /locus_tag="SPC06A_0013"
     CDS             9288..10631
                     /gene="wzy"
                     /locus_tag="SPC06A_0013"
                     /note="member of homology group 139"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI32823.1"
                     /db_xref="UniProtKB/TrEMBL:Q8RSF1"
                     /translation="MLLNFLFISIFLLIIITFILFEGDFFQPAVILTIAYFISIASAL
                     VNRNVWGTELHFKTFYLILLGVATFVIVSLLTKLSYRPKVEGISHEELKEINPSKIIY
                     VILLTLNLVMLFLYIREIQKVVLFSGRSFSNITDLISNYRYLSYYSNEVENRVSGMIN
                     QLSKIIPATTLISLYIFMNNYFITKQIKKNFIYLIPIAIFFVYAIISGGRLPLIRLVV
                     GSLLILYIYSVYGSPKSQLTKSFKMITRSLFTFLILIVLFFLLKFVLGRSSQEDFISY
                     ITRYMGGSIQLFDLFVIDPIRRNKELGAETFSGIYEMLAKLGFDNNIIKGLEWRVSPN
                     YYSLGNVYTAIRRYYSDFGVIGIVICQSFTAWLYTLGYEKVRHYSLVTNVQRFRLILL
                     AASFYPIFLNGIEDVFYISMVTIGYGIQIVIFYLVFWVLLKVQVDFNKGKLTINR"
     misc_feature    9288..9416
                     /gene="wzy"
                     /locus_tag="SPC06A_0013"
                     /note="Signal peptide predicted for SPC0135 by SignalP 2.0
                     HMM (Signal peptide probability 0.938) with cleavage site
                     probability 0.688 between residues 43 and 44"
     gene            10756..12168
                     /gene="wzx"
                     /locus_tag="SPC06A_0014"
     CDS             10756..12168
                     /gene="wzx"
                     /locus_tag="SPC06A_0014"
                     /note="member of homology group 82"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI32824.1"
                     /db_xref="UniProtKB/TrEMBL:Q9AHB1"
                     /translation="MKLKFLITNLFHVFLSNLITIVTSVIVVLILPKIMGVTEYSYWQ
                     LYIFYLTYIGFFHLGWIDGIYLKYGGLEYQNLDKKQFYSQILQFFSFLILISFLLFGF
                     NLLIVTDPNAKYIYNMTIISMIVTNLRMLFVYILQMTNRLKDSSIILISDRVIYIFLL
                     FLFIIFKWHEYKVMIWADVLGRTFSLLLSFWICKDIVFQSLSEFILDLRESFDNIRVG
                     INLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVVFPLL
                     KRTKTENLSKIYSNLRNVLMLIMFAILLFYYPLKIILDLWLPAYRDALIFMALIFPMS
                     IYEGKMALVINTYLKALRMERDILKINTLIMLFSMLVTLITTLLLNNLELTVISIVVL
                     LALRSIIAELILSKKLDISVEQDIVLELLMTIIFISSSWYLPIWLAVIVYLLAYTLYL
                     YLKRKDTKMYIEYFRKKIFE"
     misc_feature    10756..10863
                     /gene="wzx"
                     /locus_tag="SPC06A_0014"
                     /note="Signal peptide predicted for SPC0136 by SignalP 2.0
                     HMM (Signal peptide probability 0.692) with cleavage site
                     probability 0.398 between residues 36 and 37"
     gene            12662..13531
                     /gene="rmlA"
                     /locus_tag="SPC06A_0015"
     CDS             12662..13531
                     /gene="rmlA"
                     /locus_tag="SPC06A_0015"
                     /EC_number="2.7.7.24"
                     /note="member of homology group 10"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RmlA"
                     /protein_id="CAI32825.1"
                     /db_xref="GOA:Q4K2Z3"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="UniProtKB/TrEMBL:Q4K2Z3"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQSLKKN
                     EYGQYLLRLVGEA"
     misc_feature    12665..13381
                     /gene="rmlA"
                     /locus_tag="SPC06A_0015"
                     /note="HMMPfam hit to PF00483, Nucleotidyl transferase,
                     score 3.7e-121"
     gene            13532..14125
                     /gene="rmlC"
                     /locus_tag="SPC06A_0016"
     CDS             13532..14125
                     /gene="rmlC"
                     /locus_tag="SPC06A_0016"
                     /EC_number="5.1.3.13"
                     /note="member of homology group 11"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
                     RmlC"
                     /protein_id="CAI32826.1"
                     /db_xref="GOA:Q9AHA9"
                     /db_xref="HSSP:1NXM"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q9AHA9"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKNHPLLKDVKPLKKEDL"
     misc_feature    13568..14098
                     /gene="rmlC"
                     /locus_tag="SPC06A_0016"
                     /note="HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose
                     3,5-epimerase, score 4.5e-16"
     gene            14138..15187
                     /gene="rmlB"
                     /locus_tag="SPC06A_0017"
     CDS             14138..15187
                     /gene="rmlB"
                     /locus_tag="SPC06A_0017"
                     /EC_number="4.2.1.46"
                     /note="member of homology group 8"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-D-glucose 4,6-dehydratase RmlB"
                     /protein_id="CAI32827.1"
                     /db_xref="GOA:Q4K0A7"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K0A7"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAVD
                     AYDHVTDRAGHDLRYAIDASKLREELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     misc_feature    14153..15109
                     /gene="rmlB"
                     /locus_tag="SPC06A_0017"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 6.3e-05"
     misc_feature    14156..14896
                     /gene="rmlB"
                     /locus_tag="SPC06A_0017"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 5.4e-77"
     misc_feature    14156..15100
                     /gene="rmlB"
                     /locus_tag="SPC06A_0017"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.0033"
     misc_feature    14159..14971
                     /gene="rmlB"
                     /locus_tag="SPC06A_0017"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.6e-05"
     gene            15253..16104
                     /gene="rmlD"
                     /locus_tag="SPC06A_0018"
     CDS             15253..16104
                     /gene="rmlD"
                     /locus_tag="SPC06A_0018"
                     /EC_number="1.1.1.133"
                     /note="member of homology group 9"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-L-rhamnose reductase RmlD"
                     /protein_id="CAI32828.1"
                     /db_xref="GOA:Q4K2Z0"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q4K2Z0"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPVKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     misc_feature    15253..16101
                     /gene="rmlD"
                     /locus_tag="SPC06A_0018"
                     /note="HMMPfam hit to PF04321, RmlD substrate binding
                     domain, score 4.7e-147"
     misc_feature    15256..15885
                     /gene="rmlD"
                     /locus_tag="SPC06A_0018"
                     /note="HMMPfam hit to PF01370, NAD dependent
                     epimerase/dehydratase f, score 9.9e-19"
     misc_feature    15256..15897
                     /gene="rmlD"
                     /locus_tag="SPC06A_0018"
                     /note="HMMPfam hit to PF02719, Polysaccharide biosynthesis
                     protein, score 0.00013"
     misc_feature    15259..15987
                     /gene="rmlD"
                     /locus_tag="SPC06A_0018"
                     /note="HMMPfam hit to PF01073, 3-beta hydroxysteroid
                     dehydrogenase/i, score 1.7e-08"
     gene            order(16180..17133,17150..17365)
                     /gene="tnp"
                     /locus_tag="SPC06A_0019"
                     /pseudo
     CDS             join(16180..17133,17150..17365)
                     /gene="tnp"
                     /locus_tag="SPC06A_0019"
                     /note="member of homology group 12"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1670 transposase"
     misc_feature    16186..16629
                     /gene="tnp"
                     /locus_tag="SPC06A_0019"
                     /note="HMMPfam hit to PF03050, Transposase IS66 family,
                     score 8.9e-05"
                     /pseudo
     gene            17564..>17611
                     /gene="aliA"
                     /locus_tag="SPC06A_0020"
     CDS             17564..>17611
                     /gene="aliA"
                     /locus_tag="SPC06A_0020"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI32830.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ89"
                     /translation="MMKSSKLLALAGVTLL"
BASE COUNT     5688 a   2673 c   3543 g   5707 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcgta taaaaacaag
      181 ggaggactgt ataaaagaca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attctcgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga agatgaacat
      301 aaagaagcgt gtccttagtg caggtctgac ttttgcatct gctttgcttt tagctgcttg
      361 cgaccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaattac ctattagact attaaactga taatatagtc aatcgaaaca agaacaagac
      481 aaaagagcct tgtaaaaggt attgcaactt ggtaatacct tttatgaggt gctttttgat
      541 atgagtccat gttttctcaa taggattgta ctcaggtgag tagggaggaa gaggtaaaag
      601 tttattccca aactcttcac acaagagttc tagcttcccc attctatgga atcttacatt
      661 atccataata ataaccgatg gtgtggttaa tgttggtaag aaaaacttct gaaaccatac
      721 ttcaaaaaag tcgctcgtca tcgtctcttc gtaagtcatt ggagcgatta actcaccatt
      781 tgttagacct gcaaccaaag aaatcctctg atatcttctt ccagatactt tacctcttat
      841 taactgacct tttaatgagc gaccatattc tcgataaaaa taagtatcga atcctgtttc
      901 gtcaatctaa acaggtgcta ggtgctttaa tctattaaaa ttcttaagaa ataaggctac
      961 tttttctggg tcttgttcat aattagattg aaaaaagaac atgaaagatg aagcaatcaa
     1021 tgtactggat aaagttatga aaaagatttt ttaaaaagtt ttgccccttt tttgtcctct
     1081 aaatacaaaa atagccctct agaatagtac acctctgctt ctaaaacatt gctagaaatc
     1141 gatttgactg tcctgatcga tttatcatgt tcttatttca ttttactata tttttgtttc
     1201 gcgggaagtc tactaagata cttaaagatg cagatagtga aaaaaggtgt agacattacc
     1261 gtaaaaaagt gatataatcg tatgatgttc aatgtatagg tgttaatcat gagtagacgt
     1321 tttaaaaaat caagttcaca gaaagtgaag cgaagtgtta atatagtttt gttgactatt
     1381 tatttattgt tagtttgttt tttattgttc ttaatcttta agtacaatat ccttgctttt
     1441 agatatctta atttagtggt aactgcgtta gtcctactag ttgccttggt agggctactc
     1501 ctgattatct ataaaaaagc tgaaaaattt actatttttc tgttggtgtt ctctatcctt
     1561 gtcagctctg tgtcgctctt tgcagtacag cagtttgttg gactgaccaa tcgtttaaat
     1621 gcgacttcta attactcaga atattcaatc agtgtcgctg ttttagcaga tagtgagatc
     1681 gaaaatgtta cgcaactgac gagtgtgaca gcaccgactg ggactgataa tgaaaatatt
     1741 caaaaactac tagctgatat caagtcaagt cagaataccg atttgacggt cgatcagagt
     1801 tcgtcttact tggcagctta caagagtttg attgcagggg agactaaggc cattgtctta
     1861 aatagtgtct ttgaaaatat catcgagtca gagtatccag actatgcatc gaagataaaa
     1921 aagatttata ccaagggatt cactaaaaaa gtagaagctc ctaagacgtc taagaatcag
     1981 tctttcaata tctatgttag tggaattgac acctatggtc ctattagttc ggtgtcgcga
     2041 tcagatgtca atatcctgat gactgtcaat cgagatacca agaaaatcct cttgaccaca
     2101 acaccacgtg atgcctatgt accaatcgca gatggtggaa ataatcaaaa agataaatta
     2161 acccatgcgg gcatttatgg agttgattcg tccattcaca ccttagaaaa tctctatgga
     2221 gtggatatca attactatgt gcgattgaac ttcacttctt tcttgaaaat gattgactta
     2281 ttgggagggg tagatgttca taatgatcaa gaattttcaa ctctacatgg gaagttccat
     2341 ttcccagtag ggaatgtcca tctagactct gagcaggctc taggttttgt acgtgaacgc
     2401 tactcactag ccgatggaga ccgtgaccgt ggtcgcaacc aacaaaaggt cattgtagca
     2461 attattaaga agttaacttc tacagaggtt ttgaaaaact atagtagtat tcttcaagga
     2521 ttgcaggatt ctcttcaaac aaatatgccg attgagacta tgatagattt agtgaatact
     2581 cagttggaga gtggagggaa ttataaagta aattcgcaag acttgaaagg tacaggtcgg
     2641 atggatcttc cttcttatgc aatgccagac agtaacctct atgtgatgga aatagatgat
     2701 agtagtttag ctgtagttaa agcagctata caggatgtga tggagggtag atgaaatgat
     2761 agacatccat tcgcatatcg tttttgatgt agatgacggt cccaagtcaa gagaggaaag
     2821 caaggctctc ttggcagaag cctacagaca gggggtgcga accattgtct ctacctctca
     2881 ccgtcgcaag ggcatgtttg aaactccgga agagaagata gcagaaaact ttcttcaggt
     2941 tcgggaaata gctaaggaag tggcgagtga cttagtcatt gcttacgggg ctgaaattta
     3001 ctacacacca gatgttctgg ataagctggg aaaaaagcgg attccgaccc tcaatgatag
     3061 tcgttatgcc ttgatagagt ttagtatgaa tactccttat cgcgatattc atagcgcctt
     3121 gagcaagatt ttgatgttgg gaattactcc agtcattgcc cacattgagc gctatgatgc
     3181 tcttgaaaat aatgaaaaac gcgttcgaga actaatcgat atgggctgtt acacgcaagt
     3241 aaatagttca catgtcctca aacccaaact ttttggcgaa cgttataaat tcatgaaaaa
     3301 aagagctcag tattttttag agcagaattt ggtttatgtc attgcaagtg atatgcacaa
     3361 tctagacggt agacctcctc atatggcaga agcatatgac cttgttaccc aaaaatacgg
     3421 agaagcgaag gctcaggaac tttttataga caatcctcga aaaattgtaa tggatcaact
     3481 aatttaggag aaatgatgaa agaacaaaac acgatagaaa tcgatgtatt tcaattattt
     3541 aaaaccttgt ggcaacgcaa gctaatgatt ttattagtgg cacttgtgac aagtgcgggg
     3601 gcttttgcat atagcacttt tattgttaag ccagaatata cgagtaccac gcgaatttac
     3661 gtagtgaatc gcaatcaagg agacaagccg gggctgacaa atcaggattt gcaggcagga
     3721 acttatctgg taaaagacta ccgtgagatt atcctttcgc aggatgcatt ggaaaaagta
     3781 gcgacaaatt tgaagttgga tatgccagca aaaacgttag ccagcaaagt tcaagtggct
     3841 gtaccagctg acactcgtat cgtctcaatc tctgtcaagg ataaacagcc agaggaagcc
     3901 agtcgtatcg ctaattctct acgagaagtt gctgcagaaa agatcgtcgc tgtaacgcga
     3961 gtatctgatg taacgacact tgaagaagcg cgaccagcta cgactccctc ttctccaaat
     4021 gttcgacgca attccttgtt tggttttctt ggaggagcag tcgtaacagt aattgctgtt
     4081 cttttgattg agttgctcga cacccgtgtg aaacgtcctg aagatattga agatgtactg
     4141 aaaattccac ttttagggct cgttccagat tttgacaaaa tgaaatagga ggaagttatg
     4201 ccaacattag aaatctcaca ggcaaaattg gattctgtaa aaaaggcaga ggaatattat
     4261 aacgctttgt gcacgaacct acagttaagt ggagatggtt tgaaagtatt ttctatcact
     4321 tctgtgaaaa taggagaagg aaaatcaacg acttccacca atatcgcttg ggcttttgcg
     4381 cgtgcaggtt acaaaacgct gctgattgat ggagatattc gcaattctgt tatgttaggt
     4441 gtctttaaag caagggataa gattacaggc ctgacagaat ttttatcagg aactacagac
     4501 ctatcacaag ggctttgtga taccaatatc gaaaatctct ttgtaattca ggctggctct
     4561 gtgtcaccga atccgacagc tcttcttcaa agtaagaatt tcagtacaat gcttgaaacc
     4621 ttgcgtaaat attttgacta catcattgta gatactgctc ctgtcggtgt cgtgattgat
     4681 gcggctatta ttacgcgaaa atgcgatgct tctattttag tgacggaggc aggtgaaata
     4741 aatcgacggg atattcaaaa agcaaaagaa cagttggaac acacagggaa gccgtttttg
     4801 ggagttgtgt tgaataaatt cgatacttca gtagacaaat acggttctta tggaaattat
     4861 ggagattacg ggaaaaataa aaaataggtc gggggataga gatgaatgga aaaatagtaa
     4921 agtcttcatt ggccataatc cagagctttc ttgttatttt attgacttat ctacttagtg
     4981 ctgtgagaga aacggagatt gtttcaacaa cagctattgc actttatatc ctccattatt
     5041 ttgtctttta tatcagtgat tatggacagg atttctttaa aaggggatat ttgattgaac
     5101 ttgtccagac attgaaatat atcctattct ttgcactagc gattagtatt tctaattttt
     5161 tcttagagga tcgatttagt atttccagac gaggcatgat ttacttcctc acattacatg
     5221 ctctcttagt ctatgtgcta aacctattta tcaagtggta ttggaagcgg gcttatccca
     5281 actttaaagg aagtaagaag attctcctac ttacagcaac ttctcgtgtc gaaaaggtac
     5341 tggatagatt aatagaatca aatgaggttg ttggggagtt ggtagccgtc agtgtcttag
     5401 ataaaccaga ttttcagcat gattgtttaa aggtagtagc agagggggag atagtaaact
     5461 ttgcgactca tgaggtggtc gatgaagtct ttatcaatct tccaagtgaa aaatacaata
     5521 ttggagagct tgtctctcag tttgaaacga tgggaattga tgtaacagtc aatctaaatg
     5581 cttttgatcg tagtttggca cgtaacaagc aaattcgtga gatggcagga ttaaacgttg
     5641 tgactttttc tacaacattt tataagacta gtcatgtaat tgctaagcgg attattgata
     5701 tcgtgggtgc attggtaggg ctgatactat gtggtttagt cagtattgta ctggttcctt
     5761 tgattcgaaa ggatgggggc tctgctattt ttgctcagac gcgtatagga aaaaatggtc
     5821 gtcagttcac tttttataag tttcgctcta tgtgtgtaga tgccgaggcg aaaaaaagag
     5881 aactcatgga acaaaatacc atgcagggtg gaatgtttaa ggtggacgat gatcctcgta
     5941 tcacgaaaat tggtcgtttt atacggaaga ctagcttgga cgagctacca cagttttaca
     6001 atgttctaaa gggagatatg agcttggtag gtacacgacc accaacagtg gacgagtatg
     6061 agcactatac cccagaacaa aaacgccgac taagttttaa acctggcata acaggtttat
     6121 ggcaggtcag cggacgaagt gaaatcaaga atttcgatga agttgtcaaa ttagatgtgg
     6181 cctatattaa tggttggaca atctggaaag atattgaaat tttattgaaa acggttaaag
     6241 ttgtatttat gagagatgga gcgaaatagt ttggttgtgt aggatatttg tagaggtaaa
     6301 agtttcgaat atatctcact caatcttttt tataagtgaa aataaattta gaagtaggaa
     6361 ttttatgaat atagtttatg ccacagataa taattttgta gatgtattga gtgcttccat
     6421 caaatcactt tacactacta attcagattt ggatttaaat ttatggatta ttgctgataa
     6481 agtttcggat agaaataaag aaaagataaa tagattatca aaacaatttg cgcagagaga
     6541 aattaattgg atagagaacg ttgagatccc atttaaatta catttagata ggggatcaat
     6601 tagttcattt agcagattat ttctgggaag tgttcttcca tcttcaatga gtaaagttct
     6661 ttatcttgac agtgatatta ttgttatgga ttctttacga agtatttttg atattgattt
     6721 taagggtaaa attctctatg gggtgaatga tacttttaat aaagaataca agcaggtgtt
     6781 gggtatacca attgacaagc caatgtttaa tgctggagtt atgcttatta atttagagtt
     6841 atggagaaat aataacgtcg aagaaagatt tttgcaagta attcaaaagt ttaatggtac
     6901 tatattacaa ggagatttag gggttttaaa tgcagtttta tataactcat ttggtgtact
     6961 tcctccagaa tataattata tgaccatatt tgaagatttg acttatgaag aaatgatagt
     7021 ttttaaaaaa ccaattaatt attattcaaa agaggaaatt aaaaatgcca gagaacgtat
     7081 agtcttacga catttcacaa ctagtttttt atcaaaaaga ccttggcaag aaggcagtaa
     7141 tgttgcacat atagaccaat ttaaaaaata ctatgaaggt agttataaaa atgttaaaga
     7201 atctatttta ctaaaaatag ttcaaaaatt acccaaaaaa tgttcagttt ttttattagg
     7261 aattattcaa tcaaaattta gacctaaatt gtatagaatt ttgaaataag gtggatagta
     7321 ttaatgacaa aaaagaaaga attttattga aaattcaaga agaattgaaa ttattaaaag
     7381 agtttataaa aatatgttct aaaaataaaa ttaagtattt tgctcttgga ggcagtctat
     7441 taggagctgt aagacacaaa ggtttcattc cttgggatga tatggatcta agctttccaa
     7501 agagttaaat ctatgtttga aataaaggaa aaagtgttag aattagagaa tgtattaatg
     7561 agtttaggag aaagtataga tgtcaatata tagaatctgt aaagatattg aaagaaaaac
     7621 tatgtcgcct gctaaaaaag caatggctaa aaacgactat tttgcatttt atgttggaag
     7681 acctttatcc tatcttttaa cagttccttt cgtgaaaaca aatattactc ccaatcaaat
     7741 atcttattta tctataattc ctttgattgt tggatttata ataatgatat ttacaactga
     7801 tttcgttgta ttattactgg catggtttct atttttttta tggaacttac tagatggagt
     7861 agatgggaac ttagccagat atcgggagca atactcgaag gatggaagtg tagtagatgc
     7921 aatggctggc tatgtagcca tggtgttgac gtatttcggt gcaggaatag tagctgctca
     7981 tttaaacgac tcagatatct atataatttt gggtgcatta tctgggattt cattgatttt
     8041 tccaaggtta gtgatgcata agtatatcaa tacagtagct caagatgagt ctgtgagtag
     8101 cattaaagat aaatctgatt ttaatactat aaaaatactg gctctaaaca tgacatcaat
     8161 tacaggaatt ccgcaggttt tactgctatt aactatttta acaaatcagt gggtactttt
     8221 tactttagta tattttacga ttaatttttt attaatgata ttttctttgt attcattatt
     8281 caaaaaggag aatgtttaga aatgggaaag tcagttgcaa ttttaatgac cacctataat
     8341 ggtgagcgat atttgtcaca acagattgat agtattaggt ctcaaacatt cactaattgg
     8401 acacttttta ttagggatga tggatcaaaa gataaaacaa tagaagtaat acagaggtat
     8461 tctaagatag atgatagaat tagattcgtt gaaaatccct caaagtttca tggagcttat
     8521 tacaattttt ttaatctaat tgaatacgtt aaaaacaatt atcaatttga ttattacttt
     8581 ttttgtgatc aagatgatat ttggaaagag cacaagttag aaatacagct gttaagattt
     8641 tctaaagatg acatgccaga gatggtttac tctgatatgt caatgattga tgccagtaat
     8701 aatttgatag atattagtat aaataaaata atggggattg aattaccgaa cataaataat
     8761 ttgtatttta ttcatgccta tatctggggg tgtactgcag gttttaatca tgcattgcta
     8821 gagatggttc cttcagttga tattgataaa gattatttat atatagaaaa actggctcat
     8881 gatagttatt ttgcaaagtt tgcactagag tatgggaagg tgttgttctg ccctgagcaa
     8941 ctggtcttgt atcgaagaca tggacataat gtaacaacta gtcatcattt taaattatct
     9001 ccgctaaatg ttttcagaaa ggctatattg ggtttcaatg aattggcact tacacatgct
     9061 agggtatata atcaaactct ttatatgcta aaaaaagctt ctggaaaaaa tcctttaagt
     9121 gatagactac ttgaaattca ggaagtaatc aaaattggag gattaaaagg tgtgagatat
     9181 ttctatcaga atcgaatttc tcgaaagcaa ctcgtaagaa caatcggctt atataccatc
     9241 atgctttttg ggacctataa aaaatatatt atgaaagaac tcttataatg cttttaaatt
     9301 tcttattcat atctattttt ctattaatta tcattacatt tatattattt gagggggatt
     9361 tttttcaacc tgcagtaatt ttaacaatcg cttattttat ttcgattgca agtgctctag
     9421 ttaatagaaa tgtttgggga acagaactcc atttcaaaac cttttatttg atattgttag
     9481 gggttgctac atttgttata gtttccttgt tgacaaaatt gtcgtacagg cctaaagtgg
     9541 agggaatttc gcatgaagaa ttgaaagaaa taaatccttc aaagataatc tatgtcattc
     9601 ttctgactct aaatcttgtt atgttatttc tttatatccg tgaaattcag aaagtagtat
     9661 tgttttcagg tagaagtttt tctaatatta cagatttgat aagtaactat aggtacctat
     9721 cttattattc aaatgaagta gaaaatcgtg taagtggaat gattaatcaa ctatctaaaa
     9781 ttattccagc gactacactt atttctttat atatatttat gaataattat tttataacta
     9841 aacaaataaa gaaaaatttc atttatttga ttccaatagc tatattcttt gtctatgcaa
     9901 tcattagtgg tggtagattg ccccttataa ggttagttgt tggatctctg ttgatattgt
     9961 atatatactc tgtgtacggg agtcctaaat ctcaacttac caaaagtttt aaaatgatca
    10021 ctcgctctct gtttacattt cttattttga tagttttatt ctttctttta aaatttgtat
    10081 tagggcgctc ctctcaggaa gattttatca gttacatcac tcgttatatg ggaggttcaa
    10141 ttcaactatt tgatttattt gttatagatc cgatacgacg taacaaagaa ctaggtgcag
    10201 aaactttttc gggaatttat gagatgcttg caaaattagg atttgacaat aatattataa
    10261 aaggcttaga atggagagtg tctcctaatt attattcttt agggaatgtg tatactgcaa
    10321 ttagacgtta ttattcagac tttggtgtaa ttggtattgt aatttgtcag agttttacag
    10381 cgtggttata tactttaggt tatgaaaaag ttagacatta ttctttagtt acaaatgttc
    10441 aaagatttag gttgatccta ttagcagctt cattttatcc aatattttta aatggtatcg
    10501 aggatgtgtt ttatatttca atggttacca ttggatatgg aatacaaatt gttatctttt
    10561 atctggtctt ttgggttctt ctgaaagttc aggttgactt taacaaaggt aaattaacga
    10621 taaatagatg aatttagcgc taatgtattg agtcatataa agggatatat ttggtaggta
    10681 ttttaattgg aggaagagag tcttgaatgg gaagtacaaa tcttctgaaa taatttttag
    10741 gtggggagta tagctatgaa attgaagttt cttataacaa atttgtttca tgtctttttg
    10801 tctaatctga ttacaattgt cacatcggtt atagttgtac taatcttacc aaaaattatg
    10861 ggagtaactg agtatagtta ttggcaacta tatatttttt acctaacata tattggtttt
    10921 tttcatctgg gttggattga tggaatttat cttaaatatg gtggattaga gtaccagaat
    10981 ttagataaga aacagtttta ttctcaaata cttcaatttt tcagtttttt aattttaatt
    11041 tcttttctat tatttggttt taacttattg attgtgacag atccaaatgc aaaatatatt
    11101 tataacatga ctattattag tatgatagtt acaaatttaa gaatgttatt cgtttatatt
    11161 ttgcagatga caaatcgatt aaaggatagc tctataattc tgataagtga tcgcgttata
    11221 tatatttttc ttttatttct gtttattata tttaaatggc atgaatacaa ggtaatgatt
    11281 tgggcggatg ttttaggaag gacattttct ctcctacttt ctttttggat ttgtaaagat
    11341 attgtttttc aatccttatc cgagttcata ttggatctga gagagtcttt tgacaatatc
    11401 cgtgttggaa tcaatttaat gttatccaat attgcaagta gtatgattat tggtattgtt
    11461 cgaatgggaa ttcaatggaa ttggaatatc gaaacattcg ggaaagtatc actgacgcta
    11521 agcatctcta atttattaat gacttttatt aatgcgattg gtttagttgt ctttcctttg
    11581 ttaaaacgga caaaaacgga aaatttatct aaaatttatt ccaacttaag aaatgttttg
    11641 atgctgatca tgtttgcaat attgctcttt tattatcctt taaaaattat tctagatctt
    11701 tggttgccag cttatcggga tgcgttgatt tttatggctc ttatttttcc tatgtcaatt
    11761 tatgaaggga agatggcctt ggtgattaat acatatttaa aggcgctaag gatggaaaga
    11821 gatattctca aaataaatac tttgattatg ttgttcagta tgttagttac cctaataact
    11881 actctattat taaataattt agagctaacg gttatatcta tagttgtttt gctagcttta
    11941 cgtagtataa tagcagaact aattctatct aaaaaacttg atatatcagt tgagcaagac
    12001 attgtgttag aattacttat gacaattata tttatttctt caagttggta cttaccgatt
    12061 tggctcgcag taatagttta tttgttagcg tatactttat acttgtatct aaagcgtaaa
    12121 gatacaaaaa tgtatataga atattttaga aagaaaatat ttgaataaaa agaactatat
    12181 atcagttaga tggcaaattc tatttttacc tttttgtcgt ttaatagaaa atgataaaaa
    12241 atatgatatt attcttacac atatttataa gcaatttaaa tgtatcaggt gataaattaa
    12301 tttaaaataa gaatagtttc tggaacattg ctattagtgg gaacaggtta cgaaataatt
    12361 tatcaatttt aaagacgttt tttaaaatat aaaataatgg attctgtcaa caattctaaa
    12421 ttctaatagg aatgataatg ctagaaaatc agattgttca tttttcaagg aagtttattt
    12481 ttaaaataat atatctttaa gtaagaatta ttttattaga cttaacctag cctatcagtt
    12541 aaattagaat atcaactttg attaattaaa aattagcaaa atttattgac attttgtttt
    12601 tataaattgc aataaaggtc taattctgaa tttcagtgaa tataagaaag ggatcctact
    12661 aatgaaaggt attattctag caggtggttc gggaactcgc ttgtatcctt tgactcgcgc
    12721 tgcatcaaaa caacttatgc cggtttatga taaaccgatg atttactacc cactttcaac
    12781 attaatgttg gctgggatta gggatatttt gattatctca actcctcaag atttgcctcg
    12841 ttttaaagag cttcttcaag atggttctga gtttggtatt aaactttctt atgctgagca
    12901 accaagtcca gatggtttgg cacaagcctt tatcattggg gaagagttta tcggtgacga
    12961 tagcgttgcc ttgattttag gtgacaatat ctaccatggt cctggtttga gcacaatgct
    13021 tcaaaaagca gccaagaaag agaaaggtgc gactgttttt ggctaccatg tcaaggatcc
    13081 agaacgcttt ggtgttgtag aatttgatga aaatatgaat gctatctcca tcgaagaaaa
    13141 gccagaatac cctcgttcaa actatgcagt gacaggactc tatttctatg ataatgatgt
    13201 agtagagatt gccaaaagta ttaaaccaag tcctcgtggt gaattggaaa ttacagatgt
    13261 caacaaggct tacttggatc gtggtgattt gtctgttgag ctcatgggac gtggttttgc
    13321 ttggttggat actggcactc atgaaagttt actagaggct tcgcagtaca tcgaaacagt
    13381 ccaacggatg caaaatgttc aggtagcaaa cttagaagaa attgcttacc gtatgggcta
    13441 tatcagtcga gaagatgtat tggccttagc ccaatcactt aagaaaaatg aatacggaca
    13501 gtatctgctc cgtttggttg gagaagcata gatgacagat aattttttcg gtaagacgct
    13561 tgcggcacgc aaggttgaag ctattccagg catgttggag tttgatatcc ccgttcatgg
    13621 agataatcgt ggctggttta aagaaaattt ccaaaaggaa aaaatgcttc cacttggatt
    13681 tccagagtct ttctttgcag aaggaaaatt gcaaaacaat gtatccttct cacgtaaaaa
    13741 tgtccttcga ggcctccacg cagagccttg ggataagtac atctctgtag cagatggagg
    13801 gaaagttctg ggttcttggg ttgatctacg cgagggtgaa acctttggga atacctatca
    13861 gacagtgatt gatgcgagta agggaatctt tgttcctcga ggcgtagcta atggcttcca
    13921 agttttatca gatacagtgt catatagcta tctggtcaat gattactggg ctcttgaact
    13981 caaacccaag tatgcctttg tgaactacgc tgatccaagc cttggtattg aatgggaaaa
    14041 tattgcagaa gcagaggttt cagaagcaga taaaaatcat ccactactta aggatgtaaa
    14101 acctttgaaa aaagaagatt tgtaaaaagg aaagaatatg actgaataca aaaatattat
    14161 cgtgacaggt ggagctggct ttatcggttc taactttgtc cattatgttt acgagaactt
    14221 tccagatgtt catgtgacag tcctagataa gttgacttat gctggaaacc gcgcgaatat
    14281 tgaggaaatt ttaggtaatc gtgttgagtt agttgttggt gacattgctg atgcggagtt
    14341 ggtagacaag ttggctgctc aagcagatgc tatcgttcat tatgcagcgg aaagccacaa
    14401 tgataattcg ctcaatgatc catcgccatt tattcatact aacttcatcg gaacctatac
    14461 tcttttagaa gctgctcgta agtatgatat tcgcttccac catgtatcga cagatgaagt
    14521 ttatggggat ctccctttac gcgaagattt gccaggtcat ggtgaaggac caggtgagaa
    14581 atttactgct gaaacaaaat acaacccaag ctctccgtac tcatcaacca aggcagcctc
    14641 agatttgatt gtcaaagcct gggtgcgttc ttttggagtc aaggcaacga tttccaactg
    14701 ttcaaataac tacggtcctt atcaacatat cgaaaaattc atcccacgtc agattactaa
    14761 catcctaagt ggaattaagc caaaacttta cggtgaaggt aagaatgttc gtgactggat
    14821 tcataccaat gaccattctt caggagtttg gacaatcttg acaaaagggc aaatcggtga
    14881 aacctacttg attggggctg atggtgagaa gaacaataag gaagttttgg aacttatcct
    14941 taaggaaatg ggacaagctg tggatgccta tgatcatgtg actgaccgtg caggacatga
    15001 ccttcgctat gcgattgatg ccagcaagct ccgtgaggag ttggggtgga aacctgaatt
    15061 taccaacttt gaagctgggc tcaaggcaac aatcaagtgg tatacagata accaagaatg
    15121 gtggaaagca gaaaaagaag ctgttgaagc caattatgct aagactcagg agattattac
    15181 agtataaaaa gcaggaaaca gctgcttttt attgctatat tgggaagagt tacatattag
    15241 aaaggtctag agatgatttt aattacaggg gcaaatggcc aattaggaac ggaacttcgc
    15301 tatttattgg atgaacgtaa tgaagaatac gtggcagtag atgtggctga gatggacatt
    15361 accaatgaag aaatggttga aaaagttttt gaagaggtga aaccgacttt agtctaccac
    15421 tgtgcagcct acaccgctgt tgatgcagca gaggatgaag gaaaagagtt ggacttcgcc
    15481 atcaatgtga cggggacaaa aaatgtcgca aaagcatctg aaaagcatgg tgcaactcta
    15541 gtttatattt ctacggacta tgtctttgac ggtaagaaac cagttggaca agagtgggaa
    15601 gttgatgacc gaccagatcc acagacagaa tatggacgca ctaagcgtat gggggaagag
    15661 ttagttgaga agcatgtgtc taatttctat attatccgta ctgcctgggt atttggaaat
    15721 tatggcaaaa acttcgtttt taccatgcaa aatcttgcga aaactcataa gactttaaca
    15781 gttgtaaatg accagtacgg tcgtccgact tggactcgta ccttggctga gttcatgacc
    15841 tacctagctg aaaatcgtaa ggaatttggt tattatcatt tgtcaaatga tgcgacagaa
    15901 gacacaacat ggtatgattt tgcagttgaa attttgaaag atacagatgt cgaagtcaag
    15961 ccagtagatt ccagtcaatt tccagtcaaa gctaaacgtc cgctaaactc aacgatgagc
    16021 ctggccaaag ccaaagctac tggatttgtt attccaactt ggcaagatgc attgcaagaa
    16081 ttttacaaac aagaagtgag ataagtagta gaatgatttt ctagtctaat aaaagaggca
    16141 gataatgaac tccaaaggag cttaagatgt acgattatct tgttgttggt gctggtctct
    16201 ttggcgcata gctttggctc agtttctatt atcgctcaca tcatccatca gaagattaat
    16261 ctgaaggtac ccaattatcg ccaagaagaa gattgggcta ggatgggttt accaatcaca
    16321 cgtaaggaaa tctctaattg gcatatcaag gcaagtcaat actatttaga gtccctttat
    16381 aaccttttac gagaaaagtt gttagaacaa cctcttcttc atgcggatga aacctcttat
    16441 cgggttctag agagtgatag ccatctgacc tactattgga cctttttgtc tgggaaagct
    16501 gagaatcaag caatcacgct gtaccatcat gatcagcgtc ggagtggttt agtagtacaa
    16561 gaattcctag gagattattc tggctatgtg cattgtgata tgttgcggca gtaacttagg
    16621 actttagtcc tctagttctg cctatgcgat agcagtccaa ggtttaggag caaggcgacg
    16681 ctaagcttgg taaactgcga accgctagaa gcttatcgtc aactggaaga agctgaactt
    16741 gttggatgtt gggcacatgt gagaaggaag ttttttgaag cgacccccaa gcaagcagat
    16801 aaatcatcct tagaagctaa aggtttagct tattgtgatc agttattttc cctggaaaga
    16861 gactgggagg ctttgccagc tgatgaacga ctacagaaac gtcaagaaga gctccaaccc
    16921 ctaatggaag acttctttgc ttagtgccgg cgtcagtcag ttttagcagg ttcaaaacta
    16981 ggaagggcaa ttgaatacag cctcaagtat gaagaaacct ttaagactat tttgaaagac
    17041 ggacatctgg tcctttccaa taatctagct gaacgcgcca ttaaatcatt ggttatggga
    17101 cggagtaaaa gagttcagtg gactctttta gcctaagcta aattttaaaa agcgagggtg
    17161 gttattttct caaagttttg aaggagctaa agcaacagct attattatga gtttgttgga
    17221 aacagctaaa cgtcatcaat taaatagcga gaaatatcta ttctatcttc tagaatgtct
    17281 tccaaacgag gaaactctcg taaacaaaga ggttttagag gcttatttac catggactaa
    17341 agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatcc gtgagttctc
    17401 tagtctggag atttttcaat atacttcgtt attgggcgct tacaatgata ttcatatttt
    17461 ttgcaaagat gttgtttgaa aaataatttt caaaaattct gaaaattctg ttgacaactt
    17521 tctgaaaaga gtctataatg gagagaaagt tttaaaggag aaaatgatga aaagttcaaa
    17581 actacttgcc cttgcgggcg tgacattatt g
//
