LOCUS       CR931645               20538 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus pneumoniae strain Wilder (serotype 9a).
ACCESSION   CR931645
VERSION     CR931645.1
KEYWORDS    .
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20538)
  AUTHORS   Bentley,S.D., Aanensen,D.M., Mavroidi,A., Saunders,D.,
            Rabbinowitsch,E., Collins,M., Donohoe,K., Harris,D., Murphy,L.,
            Quail,M.A., Samuel,G., Skovsted,I.C., Kaltoft,M.S., Barrell,B.,
            Reeves,P.R., Parkhill,J. and Spratt,B.G.
  TITLE     Genetic analysis of the capsular biosynthetic locus from all 90
            pneumococcal serotypes
  JOURNAL   PLoS Genet. 2 (3), E31 (2006)
   PUBMED   16532061
REFERENCE   2  (bases 1 to 20538)
  AUTHORS   Bentley,S.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2004) Submitted on behalf of the Pathogen
            Sequencing Unit, Sanger Institute, Wellcome Trust Genome Campus,
            Hinxton, Cambridge CB10 1SA, E-mail: sdb@sanger.ac.uk
COMMENT     NOTE: This sequence was generated from a PCR product representing
            the region from dexB to aliA and is not necessarily responsible for
            the expressed capsule serotype. For a detailed description of how
            CDS products were predicted see the associated publication.
FEATURES             Location/Qualifiers
     source          1..20538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="Wilder"
                     /db_xref="taxon:1313"
     gene            <1..134
                     /gene="dexB"
                     /locus_tag="SPC09A_0001"
     CDS             <1..134
                     /gene="dexB"
                     /locus_tag="SPC09A_0001"
                     /codon_start=3
                     /transl_table=11
                     /protein_id="CAI32962.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZI8"
                     /translation="SNEEQDLTVEGKVKSVLIENTLAQEVFEKQILVPWDAFCVELL"
     gene            293..458
                     /gene="aliB"
                     /locus_tag="SPC09A_0002"
                     /pseudo
     CDS             293..458
                     /gene="aliB"
                     /locus_tag="SPC09A_0002"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative oligopeptide-binding protein AliB
                     (pseudogene)"
     gene            complement(order(459..995,997..1323))
                     /gene="tnp"
                     /locus_tag="SPC09A_0003"
                     /pseudo
     CDS             complement(join(459..995,997..1323))
                     /gene="tnp"
                     /locus_tag="SPC09A_0003"
                     /note="member of homology group 4"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS630-Spn1 transposase"
     misc_feature    complement(join(933..995,997..1305))
                     /gene="tnp"
                     /locus_tag="SPC09A_0003"
                     /note="HMMPfam hit to PF01710, Transposase, score 2.2e-23"
                     /pseudo
     gene            1536..2981
                     /gene="wzg"
                     /locus_tag="SPC09A_0004"
     CDS             1536..2981
                     /gene="wzg"
                     /locus_tag="SPC09A_0004"
                     /note="member of homology group 0"
                     /codon_start=1
                     /transl_table=11
                     /product="integral membrane regulatory protein Wzg"
                     /protein_id="CAI32965.1"
                     /db_xref="GOA:Q8KWQ3"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q8KWQ3"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNAASNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYGTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     misc_feature    1536..1652
                     /gene="wzg"
                     /locus_tag="SPC09A_0004"
                     /note="Signal peptide predicted for SPC0281 by SignalP 2.0
                     HMM (Signal peptide probability 0.993) with cleavage site
                     probability 0.538 between residues 39 and 40"
     misc_feature    1740..2087
                     /gene="wzg"
                     /locus_tag="SPC09A_0004"
                     /note="HMMPfam hit to PF02916, DNA polymerase processivity
                     factor, score 3e-61"
     misc_feature    2265..2708
                     /gene="wzg"
                     /locus_tag="SPC09A_0004"
                     /note="HMMPfam hit to PF03816, Cell envelope-related
                     transcriptional a, score 8.4e-70"
     gene            2983..3714
                     /gene="wzh"
                     /locus_tag="SPC09A_0005"
     CDS             2983..3714
                     /gene="wzh"
                     /locus_tag="SPC09A_0005"
                     /EC_number="3.1.3.48"
                     /note="member of homology group 1"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase Wzh"
                     /protein_id="CAI32966.1"
                     /db_xref="GOA:Q8KWQ2"
                     /db_xref="InterPro:IPR004013"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="UniProtKB/TrEMBL:Q8KWQ2"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGVTPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQEFFIDNPRKIVMDQLI"
     misc_feature    2986..3594
                     /gene="wzh"
                     /locus_tag="SPC09A_0005"
                     /note="HMMPfam hit to PF02811, PHP domain, score 6.2e-37"
     gene            3720..4415
                     /gene="wzd"
                     /locus_tag="SPC09A_0006"
     CDS             3720..4415
                     /gene="wzd"
                     /locus_tag="SPC09A_0006"
                     /note="member of homology group 2"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Wzd"
                     /protein_id="CAI32967.1"
                     /db_xref="GOA:Q4K2H5"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="UniProtKB/TrEMBL:Q4K2H5"
                     /translation="MMKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFI
                     VKPEYTSTTRIYVVNHNQGNKLGLTNQDLQAGSYLVKDYREIILSQDVLEKVATNLKL
                     DMPAKTLASKVQVTVPDDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDV
                     TTLEEARPATTPSSPNVRRNSLFGFLGGVVVTVIAVLFIELLDTRVKRPEDVEDVLQI
                     PLLGLVPDLNKMK"
     misc_feature    3720..3836
                     /gene="wzd"
                     /locus_tag="SPC09A_0006"
                     /note="Signal peptide predicted for SPC0283 by SignalP 2.0
                     HMM (Signal peptide probability 0.625) with cleavage site
                     probability 0.411 between residues 39 and 40"
     misc_feature    3741..4157
                     /gene="wzd"
                     /locus_tag="SPC09A_0006"
                     /note="HMMPfam hit to PF02706, Chain length determinant
                     protein, score 1.7e-55"
     misc_feature    4263..4340
                     /gene="wzd"
                     /locus_tag="SPC09A_0006"
                     /note="PS00217 Sugar transport proteins signature 2."
     gene            4425..5114
                     /gene="wze"
                     /locus_tag="SPC09A_0007"
     CDS             4425..5114
                     /gene="wze"
                     /locus_tag="SPC09A_0007"
                     /EC_number="2.7.10.1"
                     /note="member of homology group 3"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wze"
                     /protein_id="CAI32968.1"
                     /db_xref="GOA:Q8KWQ0"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="UniProtKB/TrEMBL:Q8KWQ0"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     LGEGKSTTSINIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDQYGSY
                     GNYGDYGKNKK"
     gene            5129..6496
                     /gene="wchA"
                     /locus_tag="SPC09A_0008"
     CDS             5129..6496
                     /gene="wchA"
                     /locus_tag="SPC09A_0008"
                     /note="member of homology group 5"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32969.1"
                     /db_xref="GOA:Q8KWP9"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP9"
                     /translation="MNGKILRSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQAFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFNISRRGMIYF
                     LTLHALLVYVLNLFIKRYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     IAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGAFVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQISGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVFM
                     RDGAK"
     misc_feature    5129..5221
                     /gene="wchA"
                     /locus_tag="SPC09A_0008"
                     /note="Signal peptide predicted for SPC0285 by SignalP 2.0
                     HMM (Signal peptide probability 0.938) with cleavage site
                     probability 0.364 between residues 31 and 32"
     misc_feature    5912..6493
                     /gene="wchA"
                     /locus_tag="SPC09A_0008"
                     /note="HMMPfam hit to PF02397, Bacterial sugar
                     transferase, score 2.4e-159"
     gene            6502..7245
                     /gene="wchO"
                     /locus_tag="SPC09A_0009"
     CDS             6502..7245
                     /gene="wchO"
                     /locus_tag="SPC09A_0009"
                     /note="member of homology group 33"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32970.1"
                     /db_xref="GOA:Q8KWP8"
                     /db_xref="InterPro:IPR004629"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP8"
                     /translation="MNERMQILGIIIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCHEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEILQDMLKVFKQRYPNLNVVGYRNGYFSPEDEKKIQEDIKGGKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQKLNLEWLFRVVN
                     EPKRLFKRYFVGNVTFIKRVLDEKRKSKK"
     misc_feature    6664..7179
                     /gene="wchO"
                     /locus_tag="SPC09A_0009"
                     /note="HMMPfam hit to PF03808, Glycosyl transferase
                     WecB/TagA/CpsF f, score 1.2e-93"
     gene            7220..8305
                     /gene="wcjA"
                     /locus_tag="SPC09A_0010"
     CDS             7220..8305
                     /gene="wcjA"
                     /locus_tag="SPC09A_0010"
                     /note="member of homology group 66"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32971.1"
                     /db_xref="GOA:Q8KWP7"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP7"
                     /translation="MKSENQKNNILHISRTMDIGGAERIVYQLSSDLKDEFDSVHVAS
                     TGGLWESKLLSKGVQHHKILDVDSKNPLTMVKILSSFYRIIKNNDITIVHTHHRMAAF
                     YIRLLKIINPKLIHVYTAHNVFKNKLPLYKFSLKKAYCVAVGKAVNDNLKHDVGISDS
                     TVIYNGVVFEKTDKLVDEIVNYNGIKLGCIARLSEQKGLTYLIDAMSLVKHRDITLFI
                     VGDGELRDELENKVKQLNLQKSVIFLGYRKDVVECINSFDYLVSSSLYEGLALNVIEA
                     FMNGKTMVASDIPGINEVVNNKNGILVPVKDDVALARAIEKLATDKKLREKLAYQAKK
                     DYETKFNYSLFLDNYRRLYRKLTGESK"
     misc_feature    7733..8224
                     /gene="wcjA"
                     /locus_tag="SPC09A_0010"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 4e-43"
     gene            8302..9390
                     /gene="mnaA"
                     /locus_tag="SPC09A_0011"
     CDS             8302..9390
                     /gene="mnaA"
                     /locus_tag="SPC09A_0011"
                     /EC_number="5.1.3.14"
                     /note="member of homology group 23"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine-2-epimerase MnaA"
                     /protein_id="CAI32972.1"
                     /db_xref="GOA:Q8KWP6"
                     /db_xref="HSSP:1O6C"
                     /db_xref="InterPro:IPR003331"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP6"
                     /translation="MKKVMLVFGTRPEAIKMCPLVNELKQNDSIKTLVCVTGQHKEML
                     EQVLEVFKVVPDHDLGIMKANQTLFSITISILDKIQAVLEQEMPDIVLVHGDTTTTFA
                     TALAAFYMGIKVGHVEAGLRTHNLQSPFPEEFNRQTTSIIADYHFAPTEVAKENLLRE
                     GRKNIFVTGNTVIDALKTTVQCNYHHPILEWAKGSKLIMLTAHRRENLGEPMENMFNA
                     VNRILDEFEDVKVVYPIHKNPKVRELASKVFGDNERMKIIEPLEVIDFHNFMDQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTEEENIYNNFKLLLEDET
                     EYNKMSKASNPYGDGMTCKRVVDIILEV"
     misc_feature    8365..9381
                     /gene="mnaA"
                     /locus_tag="SPC09A_0011"
                     /note="HMMPfam hit to PF02350, UDP-N-acetylglucosamine
                     2-epimerase, score 1.4e-181"
     gene            9432..10571
                     /gene="wzy"
                     /locus_tag="SPC09A_0012"
     CDS             9432..10571
                     /gene="wzy"
                     /locus_tag="SPC09A_0012"
                     /note="member of homology group 83"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="CAI32973.1"
                     /db_xref="InterPro:IPR007016"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP5"
                     /translation="MIKRKIYIICVLLSYFLPSFFTVGSMATIFTLLSTVIRLFVTIY
                     HVPKVFSQYKVTLIDILVVLFLFFQVFVGVQSQTVNLNYIGGQFFFLGLYSFLKYFLL
                     FDCKTTIESLFLTFILFLCVQVITQLLFPVGFDSLYPTGDNRLYFLGRKNIATPYIIV
                     GLGSFYLLNKKMNEFISLKEIIFLGLFGILSFLTQSSTAIICYVLFIFMRMLGLKENI
                     GKPYSLVSITVYICFSFSIIFSQSTILSTFTAIFSKNATFSGRINIWQLAIRIFEENF
                     WFGKGLNIDFNAWTNGIIVNSAHNTLLDILARTGIFPGILFVVVLLSLFLGKYRVKSK
                     TLLTMLISFMVYITMEATSVSILLLIIAICVYWSFGEEKLYEQVT"
     misc_feature    9432..9506
                     /gene="wzy"
                     /locus_tag="SPC09A_0012"
                     /note="Signal peptide predicted for SPC0289 by SignalP 2.0
                     HMM (Signal peptide probability 0.955) with cleavage site
                     probability 0.276 between residues 25 and 26"
     misc_feature    10194..10379
                     /gene="wzy"
                     /locus_tag="SPC09A_0012"
                     /note="HMMPfam hit to PF04932, O-Antigen Polymerase, score
                     1e-07"
     gene            10555..11424
                     /gene="wcjB"
                     /locus_tag="SPC09A_0013"
     CDS             10555..11424
                     /gene="wcjB"
                     /locus_tag="SPC09A_0013"
                     /note="member of homology group 84"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32974.1"
                     /db_xref="GOA:Q8KWP4"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP4"
                     /translation="MSKLLNAIYYRLFGLYKKIYLQVFSKKTINILGEKANLENELIV
                     SFTTIPSRLNYLPSMIKSIFNQTIIPNRFIMYVYKDEFEGINLESILETEIKNGLEIV
                     YVDENLRSHKKYFYAMKDNPNSIVILVDDDTVYSSNTIEKLVASYRKYPSCISAMRCH
                     RIKLLTDGSLAPYNEWEYEFFGDIKPSYFNFFTGCGGVLFPPTARTDEFFNISNIMNL
                     SYLADDVWLNFLAIKNRIKIVKATRCKGTPLTIDDNPEESLVYLNAIYDNNNDRCIKN
                     MVDFYHIDFSEVD"
     gene            11424..12848
                     /gene="wzx"
                     /locus_tag="SPC09A_0014"
     CDS             11424..12848
                     /gene="wzx"
                     /locus_tag="SPC09A_0014"
                     /note="member of homology group 85"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="CAI32975.1"
                     /db_xref="GOA:Q8KWP3"
                     /db_xref="InterPro:IPR002797"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP3"
                     /translation="MDISNKFKVGILYTALGKYSNVIIQLFVTAVLSRILTPEEYGVV
                     AVVNVFLVFFQILADSGIGPAIVQNKTLTQNDLNDIFTLTIYSGLILSFVFVLIGYPI
                     SIVYGNEVYIKLYSLLGMCVLFYTMTIVPQSILTRNMNFKRMNLLSLIANIFSGVIGV
                     VLAIHDFGVYSLIFSNIMKATILFFVFFSSVELSFKKKIEKTSLVKILNFSKFQFMFN
                     FLNYFARNLDNLLIGRFINPAALGYYDKAYQLSLYPNQILLQVISPVIHPIMSNFQND
                     RQKMEEVFAKIFNILLLIGMPISVYLFFNASDVITFMFGNNWFQSVPVFQILSASIWI
                     QMANSPIGIFYQASNRVDLLFKVGLLASGFNIIAIVIGLLSKSIVTIAAMLIISFIIG
                     LSLNLYVLSHVVFKNDIIKYLKIILVHLVTVIPYIIFNMIGFRFEQGVVINLVLQGLV
                     LGLIWSIGIFVTGQYKQLIMMFSR"
     misc_feature    11442..12245
                     /gene="wzx"
                     /locus_tag="SPC09A_0014"
                     /note="HMMPfam hit to PF01943, Polysaccharide biosynthesis
                     protein, score 2.4e-21"
     gene            12855..14048
                     /gene="wcjC"
                     /locus_tag="SPC09A_0015"
     CDS             12855..14048
                     /gene="wcjC"
                     /locus_tag="SPC09A_0015"
                     /note="member of homology group 86"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="CAI32976.1"
                     /db_xref="GOA:Q8KWP2"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR009695"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP2"
                     /translation="MKILFVNMFYNEEGGAQKSTKFLAEQLVKEGHEVFAYSDDAIDS
                     DIEEVINGVKVFRRRTPLFSLHYIFSAKKNPAKHFFYKIFETYNVFAKKKFIDIIEEI
                     QPDIVHFNTISGMSLSIVKEAKKRNIRTIWTLRDYWLEYPWGEKDIALIKLLNRIYRP
                     FVKKSLKHLDIVTAPSAFTLNNFINKGFINPSSQKCMAIENAVIFSKSKLENIIKRKQ
                     ETKRNPEKTNFLFVGSILEIKGVFNLVMAFKKLTNPEISLKIVGKGKDLEKLQKEIES
                     DPRIQYLGFQDTKNLYETYQNSDVLVVPSAWDEPFGRVVIEGNANGLPVITSDRGGLP
                     EIVQTVGGGEVFTDKSGNTLYSILKKFVEMENYNVYYRCILENIDIYSIEKQSEKFIS
                     LYREG"
     misc_feature    13491..13988
                     /gene="wcjC"
                     /locus_tag="SPC09A_0015"
                     /note="HMMPfam hit to PF00534, Glycosyl transferases
                     group, score 1.2e-30"
     gene            14049..14714
                     /gene="wcjD"
                     /locus_tag="SPC09A_0016"
     CDS             14049..14714
                     /gene="wcjD"
                     /locus_tag="SPC09A_0016"
                     /note="member of homology group 145"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI32977.1"
                     /db_xref="GOA:Q8KWP1"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP1"
                     /translation="MQVRHLLTYLISLPKTIFFNFKCLPINQAIHLPILVAYNVKLLN
                     LKKNVIGIETVVKFGLVRIGFSGTEIISSNRSLINLRQGKVIFKGKSVITKGCTISVT
                     GGTIILGDNFYANRNCLISCTDRLIVGNNVLLGWNVILFDSAGHTLSYDGKKKIKMTE
                     EIVIGNHVWICAEAHLLKGSKIADGSVVAYSSLVTGYFAEKNCLIGGIPAKTLRKGVS
                     WEK"
     gene            complement(14840..16066)
                     /gene="tnp"
                     /locus_tag="SPC09A_0017"
                     /pseudo
     CDS             complement(14840..16066)
                     /gene="tnp"
                     /locus_tag="SPC09A_0017"
                     /note="member of homology group 146"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative ISIS116-IS110-IS902-like transposase"
     misc_feature    complement(15047..15379)
                     /gene="tnp"
                     /locus_tag="SPC09A_0017"
                     /note="HMMPfam hit to PF02371, Transposase
                     IS116/IS110/IS902 family, score 7.4e-11"
                     /pseudo
     gene            16366..17598
                     /gene="ugd"
                     /locus_tag="SPC09A_0018"
     CDS             16366..17598
                     /gene="ugd"
                     /locus_tag="SPC09A_0018"
                     /note="member of homology group 20"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase Ugd"
                     /protein_id="CAI32979.1"
                     /db_xref="GOA:Q8KWP0"
                     /db_xref="HSSP:1DLJ"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR014028"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="UniProtKB/TrEMBL:Q8KWP0"
                     /translation="MKIAVAGTGYVGLSIAVLLAQHHEIKAVDIVAEKVELINQKKSP
                     IQDDYIEKYLVEKDLNLEATMDAKYAYEDAEFVVVAAPTNYDSKKNFFDTSAVEAVIQ
                     QVKKINPKAVIIIKSTIPVGFTESVRKKYQYKNILFSPEFLRESKALYDNLYPSRIIV
                     GTDLEDTYLKDKANIFASLLKEGAIKEDIDTLFMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDAKAIIDGIGLDPRIGNHYNNPSFGYGGYCLPKDSKQLLANYFDVPQ
                     NMMTATVESNRTRKDFIAQRILEKAGVSETDSLDAFKNTQDIVIGIYRLTMKSNSDNF
                     RHSSIQGVMKRLKAKGVTVIIYEPTLKDGETFFGNKVVNNLDKFKEASNVIVANRFEP
                     SLEDVSNKVYSRDIFKRD"
     misc_feature    16366..16920
                     /gene="ugd"
                     /locus_tag="SPC09A_0018"
                     /note="HMMPfam hit to PF03721, UDP-glucose/GDP-mannose
                     dehydrogenase, score 2e-52"
     misc_feature    16366..16986
                     /gene="ugd"
                     /locus_tag="SPC09A_0018"
                     /note="HMMPfam hit to PF01210, NAD-dependent
                     glycerol-3-phosphate deh, score 0.00028"
     misc_feature    16951..17232
                     /gene="ugd"
                     /locus_tag="SPC09A_0018"
                     /note="HMMPfam hit to PF00984, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.6e-35"
     misc_feature    17326..17577
                     /gene="ugd"
                     /locus_tag="SPC09A_0018"
                     /note="HMMPfam hit to PF03720, UDP-glucose/GDP-mannose
                     dehydrogenase, score 1.3e-05"
     gene            17810..18843
                     /gene="wcjE"
                     /locus_tag="SPC09A_0019"
     CDS             join(17810..18532,18532..18843)
                     /gene="wcjE"
                     /locus_tag="SPC09A_0019"
                     /note="member of homology group 18"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAI32980.1"
                     /db_xref="GOA:Q8KWN9"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:Q8KWN9"
                     /translation="MKSIGKRINWIDFGKGFAIFSVLVGHVLMGLYESNIFSIANDVL
                     LLLITQIYIFHIPVFFALSGYFFRPVSDMKEFWHYAKKKTIILGIPYVFYSIIHFCLQ
                     KVAGASVRVPTTIFNLLNIYKFPLGVSWYLYTLWSILIVYGLLSVVFKNRKSLLLVSV
                     FAYIFTLFIQTDIFIVQRTLVWGVCFCLGSVLSAIHFDKINLKKFLFFFVLFDFIYMF
                     AWFLFYEVGSKKDYVSYSNPGLWGIAFIVCVLVAFAIFPKMEKNFPKTFLYFTKYGKD
                     SLGIYILHAPICSMIRILMLKVGINSVFLHVVVGIVLGWYLSILATYILKKIPFLNIV
                     LLPQKYIKLK"
     misc_feature    join(17831..18532,18532..18804)
                     /gene="wcjE"
                     /locus_tag="SPC09A_0019"
                     /note="HMMPfam hit to PF01757, Acyltransferase family,
                     score 6.5e-05"
     gene            complement(order(18887..19471,19525..20193))
                     /gene="tnp"
                     /locus_tag="SPC09A_0020"
     CDS             complement(join(18887..19471,19525..20193))
                     /gene="tnp"
                     /locus_tag="SPC09A_0020"
                     /note="member of homology group 13"
                     /codon_start=1
                     /transl_table=11
                     /product="putative IS1167 transposase"
                     /protein_id="CAI32981.1"
                     /db_xref="GOA:Q4K2L1"
                     /db_xref="InterPro:IPR002560"
                     /db_xref="InterPro:IPR012287"
                     /db_xref="UniProtKB/TrEMBL:Q4K2L1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAVIRDHFLKYDRAVRCRVKIITMDMFSPYYD
                     LAKQLPNAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSR
                     KLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGLI
                     EDNLKQVHPIFQTVFKTFLKDKEKLVNTLQLHYSNAKLEATNNLIKLIKRNAFGFRNF
                     ENFKKRIFIALNIKKERTKFVLSQA"
     misc_feature    complement(join(19391..19471,19525..19737))
                     /gene="tnp"
                     /locus_tag="SPC09A_0020"
                     /note="HMMPfam hit to PF01610, Transposase, score 6.7e-44"
     misc_feature    complement(19777..19842)
                     /gene="tnp"
                     /locus_tag="SPC09A_0020"
                     /note="Predicted helix-turn-helix motif with score
                     1860.000, SD 5.52 at aa 118-139, sequence
                     ISMTDIAHQLSISTSTVIRKLN"
     gene            20491..>20538
                     /gene="aliA"
                     /locus_tag="SPC09A_0021"
     CDS             20491..>20538
                     /gene="aliA"
                     /locus_tag="SPC09A_0021"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="CAI32982.1"
                     /db_xref="UniProtKB/TrEMBL:Q4JZ89"
                     /translation="MMKSSKLLALAGVTLL"
BASE COUNT     6600 a   3080 c   4073 g   6785 t
ORIGIN
        1 tgtccaatga agagcaagac ttgacagtag aaggaaaagt caaatctgtc ttgattgaaa
       61 acaccctagc tcaagaagtc tttgaaaaac aaatcttagt tccatgggat gctttctgtg
      121 tggaattact ataaatattt tttgcagaaa aatttaaaat tgaaatcata taaaaacaag
      181 ggaggactgt ataaaaagca gaaatccttt gttttttata accaaggttt ataaactttc
      241 attctcgaaa ttcaattaac tttacaaatt cccactatta aggagaaaga agatgaacat
      301 aaagaagcgt gtccttagtg caggcctgac ttttgcatct gctttgcttt tagctgcttg
      361 cggccaatca ggttcagata caaaaactta ctcatcaacc tttagtggaa atccaactac
      421 atttaactat ctattagact attacgctga taatatagtc aattgaaaca agaacaagac
      481 aaaagagcct cgtaaaaggt attgcaactt ggtaatacct ttttgaggtg ctttttgata
      541 tgaacccatg ttttctcaat aggattgtac tcaggtgaat agggaggaag aggtaaaagt
      601 ttatgcccaa actcttcaca caagagttct agcttcccca ttctatggaa tcttgcatta
      661 tccataataa taaccgatgg tgtggttaat gttggtaaga gaaacttctg aaactaagct
      721 tcaaaaaagt cgctcgtcat cgtctcttcg taagtcattg gagcgattaa ttcaccattt
      781 gttagacctg caaccaaaga aattctctga tatcttcttc cagatacttt gcctcttctt
      841 aactgacctt ttaatgagcg accatattct cgataaaaat aagtatcgaa tcctgtttca
      901 tcaatctaaa caggtgctag gtgctttaaa ctattaaaat tcttaagaaa taaggctact
      961 ttttctgggt cttgttcata gtaggtgtgg ttcttttttt cgagtgtagc ccatagcttt
     1021 gagcgcatag tggatggtag ttggatgaca gccaaattca gaagctattt cagtcaaata
     1081 agcgtctgga ttgtcagtaa gatagttttt aagtctatct ctatcaactt ttcttggttt
     1141 tgttcctttt acttggtggt ttagctctcc tgttttctct tttagcttta accagccata
     1201 aatggtatta cgtgagattt ggaaaacgtg tgacgcttct gttatactat ctgttcgctc
     1261 acaataagag agaacttttt tacgaaaatc tattgaatat gccataaaaa gattatacca
     1321 cattgtgtac tatattagat tgaaactaga atagtacaca tctgcttcta aaacattgtt
     1381 agaaatcgat ttgactgtcc ttatttcatt ttattatatt tttggttcgc gggaagtcta
     1441 ctaagatact taaagatgca gatagtaaaa aaaatgtaga cattaccgta aaaaagtgat
     1501 ataatcgtat gatgttcaag gtataggtgt taatcatgag tagacgtttt aaaaaatcag
     1561 gttcacagaa agtgaagcga agtgttaata tcgttttgct gactatttat ttattgttag
     1621 tttgtttttt attgttctta atctttaagt acaatatcct tgcttttaga tatcttaacc
     1681 tagtggtaac tgcgttagtc ctactagttg ccttggtagg gctactcttg attatctata
     1741 aaaaagctga aaagtttact atttttctgt tgctgttctc tatccttgtc agctctgtgt
     1801 cgctctttgc agtacagcag tttgttggac tgaccaatcg tttaaatgcg gcttcgaatt
     1861 actcagaata ttcgatcagt gtcgctgttt tagcagatag tgagatcgaa aatgttacgc
     1921 aactgacgag tgtgacagca ccgactggga ctgataatga aaatattcaa aaactactag
     1981 ctgatatcaa gtcaagtcag aataccgatt tgacggtcaa ccagagttcg tcttacttgg
     2041 cagcttacaa gagtttgatt gcaggggaga ctaaggccat tgtcctaaat agtgtctttg
     2101 aaaatatcat cgagtcagag tatccagact acgcatcgaa gataaagaag atttatacca
     2161 agggattcac taaaaaagta gaagctccta agacgtctaa gaatcagtct ttcaatatct
     2221 atgttagtgg aattgacacc tatggtccta ttagttcggt gtcgcgatca gatgtcaata
     2281 tcctgatgac tgtcaatcga gataccaaga aaatcctctt gaccacaacg ccacgtgatg
     2341 cctatgtacc aatcgcagat ggtggaaata atcaaaaaga taaattaacc catgcgggca
     2401 tttatggagt tgattcgtcc attcacacct tagaaaatct ctatggagtg gatatcaatt
     2461 actatgtgcg attgaacttc acttctttct tgaaattgat tgacttattg ggaggggtag
     2521 atgttcataa tgatcaagag ttttcagctc tacatgggaa gttccatttc ccagtaggga
     2581 atgtccatct agactctgag caagctctag gttttgtacg tgaacgctac tcactagccg
     2641 atggagaccg tgaccgtggt cgcaaccaac aaaaggtgat tgtggctatc cttcaaaaat
     2701 taacgtcaac cgaagcactg aaaaattatg gtacgatcat taatagcttg caagattcta
     2761 tccaaacaaa tatgccactt gagaccatga taaatttggt caatgctcag ttagaaagtg
     2821 gagggaatta taaagtaaat tctcaagatt taaaagggac aggtcggatg gatcttcctt
     2881 cttatgcaat gccagacagt aacctctatg tgctggaaat agatgatagt agtttagctg
     2941 tagttaaagc agctatacag gatgtgatgg agggtagatg aaatgataga catccattcg
     3001 catatcgttt ttgatgtaga tgacggtccc aagtcaagag aggaaagcaa ggctctcttg
     3061 gcagaatcct acaggcaagg ggtgcgaacc attgtctcta cctctcaccg tcgcaagggc
     3121 atgtttgaaa ctccggaaga gaagatagca gaaaactttc ttcaggttcg ggaaatagct
     3181 aaggaagtgg cgagtgactt ggtcattgct tacggggctg aaatttacta cacaccagat
     3241 gttctggata agctggaaaa aaagcggatt ccgaccctca atgatagtcg ttatgccttg
     3301 atagagttta gtatgaacac tccttatcgc gatattcata gcgccttgag caagatcttg
     3361 atgttgggag ttactccagt cattgcccac attgagcgct atgatgctct tgaaaataat
     3421 gaaaaacgcg ttcgagaact gatcgatatg ggctgttaca cgcaagtaaa tagttcacat
     3481 gtcctcaaac ccaaactttt tggcgaacgt tataaattca tgaaaaaaag agctcagtat
     3541 tttttagagc aggatttggt tcatgtcatt gcaagtgaca tgcacaatct agacggtaga
     3601 cctcctcata tggcagaagc atatgacctt gttacccaaa aatacggaga agcgaaggct
     3661 caggaatttt ttatagacaa tcctcgaaaa attgtaatgg atcaactaat ttaggagaaa
     3721 tgatgaaaga acaaaacacg atagaaatcg atgtatttca attatttaaa accttgtgga
     3781 aacgcaagct aatgatttta atagtggcac ttgtgacagg tgcgggggct tttgcatata
     3841 gcacttttat tgttaagcca gaatatacga gtaccacgcg aatttacgta gtgaatcaca
     3901 atcaaggaaa caagctgggg ctgacaaatc aggatttgca ggcaggttct tatctggtaa
     3961 aagactaccg tgagattatc ctttcgcagg atgtattgga aaaagtagcg acaaatttga
     4021 agttggatat gccagcaaaa acgttagcca gcaaagttca agtgactgta ccagatgaca
     4081 ctcgtatcgt ctcaatctct gtcaaggata aacagccaga ggaagccagt cgtatcgcta
     4141 attctctacg agaagttgct gcagaaaaga tcgtcgctgt aacgcgagta tctgatgtaa
     4201 cgacacttga agaagcgcga ccagctacga ctccctcttc tccaaatgtt cgacgcaatt
     4261 ccttgtttgg ttttcttgga ggagtagtcg taacagtaat tgctgttctt tttattgagt
     4321 tgctcgacac ccgtgtgaaa cgtcctgaag atgttgaaga tgtactgcaa attccacttt
     4381 tagggctcgt tccagatttg aacaaaatga aataggagga agttatgcca acgttagaaa
     4441 tctcacaggc aaaattggat tttgtaaaaa aggcagagga atattataac gctttgtgca
     4501 cgaacctaca gttaagtgga gatggtttga aagtattttc tatcacttct gtgaaactag
     4561 gagaaggaaa atcaacgact tccatcaata tcgcttgggc ttttgcgcgt gcaggttaca
     4621 aaacgctgct gattgatgga gatattcgca attctgttat gttaggtgtc tttaaagcaa
     4681 gggataagat tacaggcctg acagaatttt tatcaggaac tacagaccta tcacaagggc
     4741 tttgtgatac caatatcgaa aatctctttg taattcaggc tggctctgtg tcaccgaatc
     4801 cgacagctct tcttcaaagt aagaatttca gtacaatgct tgaaaccttg cgtaaatatt
     4861 ttgactacat cattgtagat actgctcctg tcggtgtcgt gattgatgcg gctattatta
     4921 cgcgaaaatg cgatgcttct attttagtga cggaggcagg tgaaataaat cgacgggata
     4981 ttcaaaaagc aaaagaacag ttggaacaca cagggaagcc gtttttggga attgtgttga
     5041 ataaattcga tacttcagta gaccaatacg gttcttatgg aaattatgga gattacggga
     5101 aaaataaaaa ataggtcggg ggatagagat gaatgggaaa atattaaggt cttcattggc
     5161 cataatccag agttttcttg ttattttatt gacttatcta cttagtgctg tgagagaagc
     5221 ggagattgtt tcaacaacag ctattgcact ttatatccta cattattttg tcttttatat
     5281 cagtgattat ggacaggctt tctttaaaag gggatatttg attgaacttg tccagacatt
     5341 gaaatatatc ctattctttg cactagcgat tagtatttct aattttttct tagaggatcg
     5401 atttaatatt tccagacgag gcatgattta cttcctcaca ttacatgctc tcttggtcta
     5461 tgtgctaaac ctatttatca agcggtattg gaagcgggct tatcccaact ttaaaggaag
     5521 taagaagatt ctcctactta cagcaacttc tcgtgtcgaa aaggtactgg atagattaat
     5581 agaatcaaat gaggttgttg gggagttgat agccgtcagt gtcttagata aaccagattt
     5641 tcagcatgat tgtttaaagg tagtagcaga gggggagata gtaaactttg cgactcatga
     5701 ggtggtcgat gaagtcttta tcaatcttcc aagtgaaaaa tacaatattg gagagcttgt
     5761 ctctcagttt gaaacgatgg gaattgatgt aacagtcaat ctaaatgctt ttgatcgtag
     5821 tttggcacgt aacaagcaaa ttcgtgagat ggcaggatta aacgttgtga ctttttctac
     5881 aacattttat aagactagtc atgtaattgc taagcggatt attgatatcg tgggtgcatt
     5941 tgtagggctg atattatgtg gtttagttag tattgtactg gttcctttga ttcgaaagga
     6001 tgggggctct gctatttttg ctcagacgcg tataggaaaa aatggtcgtc agttcacttt
     6061 ttataagttt cgctctatgt gtgtagatgc cgaggcgaaa aaaagagaac tcatggaaca
     6121 aaataccatg cagggtggaa tgtttaaggt ggacgatgat cctcgtatca cgaaaattgg
     6181 tcgttttata cggaagacta gcttggacga gctaccacag ttttataatg ttctaaaggg
     6241 agatatgagt ttggttggca cacggccacc aacagtggac gagtatgaac actatacccc
     6301 agaacaaaaa cgtcggctaa gttttaaacc tggtataaca ggcttatggc agatcagtgg
     6361 acgaagtgag attaagaatt ttgatgaagt tgtcaaatta gatgtggcct atattgatgg
     6421 ttggacaatc tggaaagata ttgaaatttt gcttaaaact gttaaagttg tatttatgag
     6481 agatggagcg aagtaattca tatgaatgag agaatgcaaa tattaggaat tattatagat
     6541 ccattaacga tgaaagaaac agtggatgct gttgaacagt atgttttaaa gaagcatcct
     6601 ttgcacttga tgggagttaa cgcagataaa attaatcagt gccatgaaga tgagaaaatc
     6661 aaaaaaatcg ttaatgaatc aggaatcatt aatgcggatg gagcatcagt tgttcttgca
     6721 agtaagtttt taggaacgcc tgttcctgaa cgagtagcgg gtattgattt gatgcaatgt
     6781 cttttagagt tgtcaaataa aaaaggatat tcagtttact tttttggagc caaagaagaa
     6841 attttacaag atatgctaaa agtttttaaa caaagatatc ctaatcttaa tgttgttggc
     6901 tatagaaacg gatatttttc acctgaagat gaaaaaaaga ttcaggaaga tattaaagga
     6961 ggcaaaccag attttgtatt tgtagggatt acttctccta aaaaggaata tatcatccaa
     7021 tcattcatgg ataatgggat taatgctgtc tttatgggtg ttggtggcag ttttgatgta
     7081 ttatcaggac acattaaacg agctccatta tggatgcaaa aattgaatct ggaatggttg
     7141 ttccgtgtag ttaatgaacc caaacgtctt tttaagcgtt attttgtagg gaatgttact
     7201 tttattaagc gagttttaga tgaaaagcga aaatcaaaaa aataatattc tacatatttc
     7261 tcgtacaatg gatattggtg gtgcagaacg tattgtatat caattgagtt ctgatttgaa
     7321 agatgaattt gatagtgtcc atgtcgcttc aacaggtgga ctatgggaga gcaaactttt
     7381 atcaaaagga gttcaacatc ataaaatttt agatgttgac agtaagaatc ccctaactat
     7441 ggtaaagatc ctttcaagtt tttatagaat tatcaaaaat aatgatatta ccattgttca
     7501 cactcatcat cggatggctg ccttttatat tcgcttgttg aaaatcatta atcctaagtt
     7561 gatacatgtt tacactgcac ataatgtatt taaaaataaa ttaccattat acaaattttc
     7621 cttaaaaaaa gcgtattgtg tagctgtggg taaagcggtt aatgataatt tgaaacatga
     7681 tgtaggaatc agtgatagta cagtaatcta taatggggtt gtttttgaaa aaactgataa
     7741 gctagttgat gagattgtaa attataacgg aatcaaattg gggtgtattg ctaggttatc
     7801 agagcaaaaa ggattgacct acctaattga tgcgatgtct ttagtgaaac acagggatat
     7861 tacattgttc attgtcggag atggagagct tcgagatgaa cttgaaaaca aggtgaaaca
     7921 attaaatctt caaaaatcag tgatattttt aggttatcga aaagatgttg ttgaatgtat
     7981 caatagtttt gattacttag tgtcatcatc tttatatgag gggttggctc taaatgtaat
     8041 tgaagcattt atgaatggga aaacgatggt tgcatcagat atccccggaa taaatgaagt
     8101 agtcaataac aaaaatggga ttcttgttcc tgttaaggat gatgttgcct tagcgagagc
     8161 gattgaaaag cttgcgactg acaaaaaact tagagaaaaa ctcgcttatc aagcaaaaaa
     8221 agactatgag acaaaattta attattcctt gtttttggat aattatcgga gactttatag
     8281 aaaattaacg ggagaatcaa aatgaaaaaa gtcatgttgg tttttgggac acgtccagag
     8341 gctattaaaa tgtgtcccct agtaaatgaa ctgaaacaaa atgattcaat caagacactt
     8401 gtgtgtgtaa ctggtcaaca taaggaaatg ctagagcagg ttttggaggt gttcaaggtt
     8461 gtcccagatc atgatttggg tatcatgaaa gcaaatcaaa ccctattttc cattacgatt
     8521 agtattttgg ataagattca agcagttcta gaacaagaaa tgcctgatat cgttcttgtt
     8581 catggagata caacaacaac atttgcgaca gctttggcag cattttatat gggaatcaaa
     8641 gtgggacacg tcgaagccgg tctcagaacc cacaatctcc aaagtccatt tccagaggag
     8701 ttcaatcgcc agacgacttc tatcattgcc gactatcatt tcgcgccgac tgaagttgca
     8761 aaggaaaatc tactaagaga gggcagaaaa aatatctttg tgacgggaaa tacagtcatt
     8821 gatgctttga agacgactgt tcaatgcaac tatcatcacc caattttgga atgggcaaag
     8881 ggtagtaagt taatcatgct aacggctcat cgacgagaaa atcttgggga accgatggaa
     8941 aacatgttta atgctgttaa tcgaatttta gacgaatttg aagatgtaaa agttgtatat
     9001 cccatccata aaaatcctaa ggttcgagag ttggcaagta aagtttttgg cgataatgaa
     9061 cgaatgaaga tcattgaacc gttagaagtt attgatttcc ataattttat ggatcaaagc
     9121 tatatgattt tgacagattc tggaggtgtg caggaagaag caccttcttt agggaaacct
     9181 gtcttagtga tgcgtgatac aacagagcgt cctgaaggag tcgctgctgg cacattgaag
     9241 ttggtaggta cagaagaaga gaatatttat aataacttta aacttcttct tgaggatgaa
     9301 acagaatata acaagatgag taaagctagc aatccttatg gagatggaat gacttgtaaa
     9361 cgggttgttg atattattct ggaagtataa aaataattca attatgaatg aggaaagaat
     9421 aaattagatt gatgataaaa agaaaaatat atataatctg tgtattactg tcgtattttt
     9481 tacctagttt ttttacagtt ggatcaatgg caactatatt taccctactc tccacagtaa
     9541 ttaggctatt cgtaactata tatcatgttc ctaaagtttt ttcacagtat aaggtaacgc
     9601 tgattgacat tttggttgtt ctgtttttgt tttttcaagt gtttgtgggg gttcaaagtc
     9661 agacagtgaa tcttaactat attggaggac agtttttctt tttaggatta tattcatttt
     9721 tgaaatactt tttattgttt gattgtaaaa caacaattga aagcctcttt ttaaccttta
     9781 tcttgttttt gtgtgttcaa gtaataactc aattgctttt tccggttggt ttcgactctt
     9841 tgtaccctac aggagataat agactttact ttttaggaag aaaaaacata gccaccccat
     9901 atatcattgt tggattaggt agtttttact tattaaataa aaaaatgaat gagtttatat
     9961 cactaaagga gattattttt ttaggattgt tcggaatttt atcattttta acacaatcca
    10021 gtacagcgat tatatgttat gtgcttttta tttttatgcg tatgttaggt ttaaaggaaa
    10081 atataggaaa accatattct ttagtcagta taactgtgta tatttgtttt agtttttcta
    10141 taattttttc acaaagtaca attttatcaa cttttacagc aattttttcc aaaaatgcaa
    10201 ccttttcagg acgtatcaat atttggcagt tagcgattcg tatttttgaa gaaaattttt
    10261 ggtttggaaa aggacttaat attgatttca atgcttggac aaatgggatt atcgttaact
    10321 ccgcacacaa taccttacta gatatacttg ctcgaacggg tatatttccg ggtattttat
    10381 ttgtagtggt tcttctaagt ctatttcttg gaaaatatag agtaaaatca aaaacgctac
    10441 tgacaatgtt gatttcattc atggtttata ttacgatgga ggctacatct gtaagtattc
    10501 ttctattaat aattgctatt tgtgtgtatt ggtcttttgg agaggagaag ttatatgagc
    10561 aagttactta atgcaatcta ttatcgacta tttggattat ataaaaaaat ttatctacaa
    10621 gtttttagta aaaaaacaat taatatttta ggtgaaaagg ctaatttaga aaatgaacta
    10681 attgtttcgt ttacaacaat tccaagccgt cttaattatt taccaagtat gattaaaagt
    10741 attttcaatc agacaattat ccctaaccgt tttattatgt atgtttataa agatgaattt
    10801 gaaggtatta atttggagag tatcctagaa actgaaatca aaaatggttt ggaaattgtc
    10861 tatgtggacg aaaatcttcg ctcgcataaa aaatattttt atgctatgaa ggataatccg
    10921 aatagtattg taattttggt tgatgatgac actgtctatt catcgaatac catcgaaaag
    10981 ttagttgctt cttacaggaa atacccaagt tgtatttcgg caatgcgatg tcatcgaatt
    11041 aaactgctta ctgatggaag tctggcacca tacaatgagt gggaatatga atttttcggt
    11101 gatattaaac catcttactt taatttcttt acaggttgtg gaggagtact ttttcctcct
    11161 actgctcgaa cagatgaatt ttttaatatt tctaatataa tgaatctcag ttatttagct
    11221 gatgatgtat ggttgaattt tttagcaata aaaaatagaa ttaaaatagt aaaagcaaca
    11281 cgatgtaagg gaacaccatt aactatagat gacaaccctg aagagagttt ggtgtatctg
    11341 aatgctatat atgataataa taatgatagg tgtatcaaga atatggtaga tttttatcat
    11401 attgattttt cagaggttga ttaatggata taagtaataa gtttaaggta ggtatcctat
    11461 atactgcttt aggtaagtat tctaatgtta taattcaatt atttgtaacg gcggtattaa
    11521 gtagaatatt aacacctgaa gagtatggcg ttgtagcggt tgtcaatgtg tttttagtat
    11581 tctttcagat attggcagat tcgggaatag gacctgcaat tgtacaaaat aagacattaa
    11641 ctcaaaatga tttaaatgat atttttactt taacaattta ttcaggttta attctttcgt
    11701 ttgtttttgt attgataggc tatccaatta gtatagtcta tgggaatgaa gtctatatca
    11761 aactgtactc attattaggt atgtgtgtac tattttatac tatgacaatt gttcctcagt
    11821 caattttaac aagaaacatg aactttaaac ggatgaactt attgagtctg attgccaata
    11881 tttttagtgg agttattggt gttgtgctgg ccatacatga tttcggggta tattctctga
    11941 ttttttctaa tattatgaag gctactatat tattttttgt ttttttttca agtgttgagt
    12001 tgagttttaa gaaaaagata gagaaaactt cgttagttaa aattctaaat ttttctaagt
    12061 ttcaatttat gtttaatttt ctaaactact ttgcaagaaa tttagacaat ctcttgattg
    12121 gtagattcat taatcccgct gcgttgggtt attatgataa ggcttaccag ttatcattat
    12181 atcctaatca gattttattg caggtgattt cacctgtaat tcatccgata atgtcgaatt
    12241 ttcaaaatga tagacaaaaa atggaagaag tttttgcaaa aatttttaat attctacttt
    12301 taataggaat gccaatctca gtgtatttgt ttttcaatgc aagtgatgtg ataacattta
    12361 tgtttggaaa taattggttt cagagcgttc cagtatttca aatactatct gctagcatct
    12421 ggattcaaat ggctaatagt ccaataggaa ttttttatca agcttcgaat cgtgttgatc
    12481 tgttatttaa ggtaggatta ttagcgtcag gatttaatat tatagctatt gtgatagggc
    12541 tattatcgaa aagtatagtg acaattgctg ctatgttaat tatttcattt ataatagggc
    12601 tatcactgaa tctctacgtt ttatcacatg tagtctttaa aaatgatata attaaatatt
    12661 taaaaataat tttagttcac cttgtaacag ttatcccata tattatattc aatatgattg
    12721 gctttagatt tgaacagggt gtagttatca atcttgtgtt gcaaggactg gtattgggac
    12781 taatttggtc tataggaata tttgtaacag gtcaatacaa gcagttaata atgatgttta
    12841 gtaggtgaaa atttatgaaa attttatttg tgaatatgtt ttacaatgaa gaaggaggag
    12901 cacaaaagag caccaaattt ctagctgaac aacttgtaaa agaaggacat gaggtatttg
    12961 catactctga tgatgctatt gattcagata ttgaggaagt tattaatggg gttaaggttt
    13021 ttagaagaag aactccgctt tttagtcttc actatatttt cagtgccaag aagaatccag
    13081 ctaaacattt tttctataaa atatttgaaa cctataatgt atttgcgaaa aaaaaattta
    13141 tcgatatcat tgaggaaata caaccagata ttgttcattt taatacaatt tcaggaatgt
    13201 ctttatcaat agttaaagaa gctaaaaaga gaaatatcag aaccatttgg accttgcgag
    13261 actattggct agaatatcca tggggggaga aagatattgc tcttattaaa ctgctaaata
    13321 gaatatatag accttttgtt aagaaaagtt taaaacactt agacatagta acagcacctt
    13381 cagcatttac cttgaataat tttatcaata aaggatttat taacccatct tctcaaaaat
    13441 gtatggccat tgaaaatgct gttatatttt caaagagtaa attggaaaat attatcaaac
    13501 gaaagcaaga aacaaaaaga aatccagaaa aaacgaattt tctttttgta ggctctatac
    13561 ttgaaataaa gggcgttttt aacttagtaa tggcttttaa aaaactaact aatccagaaa
    13621 tttctttgaa aattgtagga aaaggaaaag atttagaaaa acttcaaaaa gaaatcgaaa
    13681 gtgatcctag aatacaatat ttaggctttc aagatacaaa aaacctctat gaaacttatc
    13741 aaaattcgga tgtattggtc gttccatcag cttgggatga accgtttggt agagttgtaa
    13801 ttgaaggaaa tgcaaatggc cttccggtca tcacttcaga tagaggtgga ttacctgaaa
    13861 ttgtgcaaac agtaggagga ggggaagttt ttacagacaa atcgggaaat acattatata
    13921 gtattttaaa gaaatttgta gaaatggaaa actacaatgt ctattaccga tgcattcttg
    13981 agaatattga tatttattct atcgaaaaac aaagtgaaaa gtttataagt ttatataggg
    14041 agggatagat gcaggttcga catttattaa cttatctgat ttcgctacct aaaacaatct
    14101 tttttaattt taagtgttta ccaattaatc aggcaattca ccttccaata cttgtagcat
    14161 ataatgtcaa gttgttaaat ttgaaaaaga atgtaattgg tatagaaact gtagtaaaat
    14221 ttggtttagt tcgaattggt ttctcaggta cggagataat atcctctaat cgatcgctca
    14281 taaacttgag acaaggaaaa gttattttta aagggaagtc agtgatcaca aaaggttgca
    14341 caattagtgt tacaggagga accatcattt tgggcgataa cttttatgcg aatagaaatt
    14401 gtcttatatc atgtactgat aggctcattg ttggtaataa tgtactttta ggttggaatg
    14461 ttattctttt tgactcagct ggtcatacac taagctacga tggtaagaaa aagataaaaa
    14521 tgacagaaga aattgtaatt ggtaaccatg tatggatttg tgctgaagca cacttattga
    14581 aaggaagtaa gattgcagat ggttctgtag tagcttattc tagtttagtt acaggttatt
    14641 tcgcagaaaa gaattgcttg attggaggaa tacctgcaaa aacacttaga aaaggagtaa
    14701 gttgggaaaa gtaactttat tttattgatt caaaatatta gaggtggaag tttgaaaaaa
    14761 ataaaagtta gttgattgat tacttctcta aattttgggc acactaaaaa gaggtcttga
    14821 cacctaaact ttaaaattaa agcatattga atccgcgctg ctgtgcgaag cgaatagcgt
    14881 cttggacgga cattgtctta tctggatttc ttatttctgt aaggccttgt aatcttggat
    14941 tataactctc ctgttttagg aatacatggt agatggcaac caataatctg cgacagatag
    15001 cgatgatagc ttttcgatga ccacgtcgtt tcttgagttt gagatattta tttcgtagtt
    15061 caggatgctt ctctgattta accacggcat tagctatttg aacaagaaaa ggtttgagat
    15121 agtgaccgcc tttcgaaata cgagtagaga atttctttcc tgcactttca ttgttggcag
    15181 gaactaatcc gccccaagaa tagagtttac ctgcagtacc aaagacagtc atatcagctc
    15241 cgatttcaga gagtattctg agggcagata gttcctcttt gaaaccaggc acagtttgga
    15301 tcagtttgac ctgttcttgg tattcgtgac cgagcttccg aatcatggtt tctaaatctt
    15361 ctttacagac ggcaagagca tcatagtgtt ccttgatgat tctgattttc tcagcttgtt
    15421 caggtgtcac ctccccctca atagcgattt tcaagtcttg caccttatcc ttcattctct
    15481 tgtgaatcaa ctgttcaatg tttggtttgt cctctggatt gtcaaggatg ctctgaataa
    15541 tagcctgagc actttttccg aacacgtcgg aaacgacact tgcaatctga aggttagacc
    15601 aagtcagaca gttctggtaa cgatttttct cgctgacttg aagttgtgtt aatttcatgc
    15661 gatagcgaaa aaggtctcgg agttgtctga ttttaagagg gggaataaag ctagaagcaa
    15721 ccaaatcatg cttgaagagg tcggctatcc attgcgcatc tttcttgtcg gttttctttc
    15781 ctctgatagc cttgacatac ttagggtgag ctaagcaaat cttgcaggat ttttcaagga
    15841 tattgaagac aggaatccaa tatttactgg tagattccat acagacatca aatcaagaat
    15901 agtattctag ccaatctcgt agctgtacta acccatttgt aaaagttgag aaacgtttac
    15961 gatggtagct tgtgagtcct tgcttgtcgg tgatggtaac aaccgctaca acaaaggttt
    16021 tatgcacatc aatgccacaa caattaggat agataatttt taacatgagg ggtctccctt
    16081 caccaaattt gagtctgcct atcccttgac tattctttcc tttcacaaac gagtcgctta
    16141 ttcaattata agtttacgtg ctcttagtca cagttcttgt gcttgatgga aagaatgaca
    16201 cctataaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
    16261 atagtgatag gctttctcac tattattata aaccaaaata aagagcacaa cactttttca
    16321 tgctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aatagcggta
    16381 gcaggaacag gttatgtagg attgtcaatt gccgtgttgt tggcacaaca tcacgaaata
    16441 aaagcagttg atattgttgc tgaaaaagtt gaattaatca atcaaaaaaa atctccaatt
    16501 caggatgatt atattgaaaa atatttagtg gaaaaagatt taaatttgga agcaactatg
    16561 gatgctaagt atgcttatga agatgcagaa tttgttgttg ttgcagcacc aacaaattat
    16621 gattcgaaaa agaacttttt tgatacatca gcagtagagg cggtcattca acaagtaaaa
    16681 aaaattaatc ccaaagcggt aataattatt aaatctacaa tccctgttgg attcacagag
    16741 tccgttcgaa agaaatatca gtataaaaat atcctattta gtccagaatt tttacgcgaa
    16801 tctaaagcat tatacgataa cctgtatcca agtcgcatca ttgttggaac tgacttagaa
    16861 gatacttatt taaaagacaa agctaatata tttgcttccc tactaaaaga gggggctatt
    16921 aaagaagaca tagatacact tttcatggga gtaacggaag ctgaggcagt taaattattt
    16981 gccaatactt accttgcgtt gcgtgtttct tactttaatg aattggatac ttatgcagag
    17041 gtgaaaggtt tggatgcaaa agccattatt gatggtattg gcctagatcc acgtatagga
    17101 aatcattata acaatccatc ctttggctac ggtgggtatt gtttacctaa agatagtaag
    17161 cagttattag caaattactt tgatgtacca caaaatatga tgacggcaac tgttgaaagc
    17221 aatcgaacgc gtaaggattt tatcgctcaa cggattttag aaaaagctgg agtatctgag
    17281 actgatagtt tagatgcgtt taagaacaca caagatattg ttataggtat ttatcgttta
    17341 acaatgaaaa gtaattcgga taacttccgt cactcctcta ttcaaggtgt tatgaaacga
    17401 ttgaaagcta agggagttac ggttatcatc tatgagccaa ctttgaagga cggggaaaca
    17461 ttctttggta ataaagtggt aaataatcta gataaattta aagaagctag taatgttatt
    17521 gtagccaatc gttttgaacc ttcactagag gatgtgtcta ataaagttta tagtcgggat
    17581 atttttaagc gtgactaata aatatgtcca cgtgacgtaa tatctattaa atggataaaa
    17641 tattaataaa catggcatct atatcttttt ggggataata aaaggcatat gattatctaa
    17701 gttagtttat ataattaagc agttacgtca acttatttta ttatgaatta tatataacat
    17761 gaatatcatt attaaatgag cactaaatag ataacaagag gagaaataaa tgaaatcaat
    17821 cggaaagcga atcaattgga tagattttgg gaaaggattc gcaatatttt cagttctagt
    17881 aggacatgta ttgatggggt tgtatgaatc caatattttt tcaattgcaa atgatgtgtt
    17941 attattattg ataactcaaa tttatatatt tcacatacca gtgttttttg ccctgtcagg
    18001 atactttttt agacctgtat cagatatgaa ggagttttgg cattatgcta aaaagaagac
    18061 gattatttta ggtataccat atgtttttta ttcaattatt cacttttgtc ttcaaaaggt
    18121 cgctggtgcc tctgtccgag tacccactac gatatttaac ctattgaata tctataaatt
    18181 tcctctggga gtttcatggt atctatatac gttatggtcg atattgatag tttatggttt
    18241 actatctgtt gttttcaaaa atcgtaagtc ccttttgtta gttagtgttt ttgcctatat
    18301 tttcacacta tttattcaaa ctgatatttt tattgtacaa cggacgttgg tttggggtgt
    18361 ttgcttctgt cttggcagtg tattgagcgc aattcacttt gataaaatta atttgaaaaa
    18421 atttcttttt ttctttgtgc tatttgattt tatttatatg ttcgcttggt ttttgtttta
    18481 tgaagtaggg tctaagaagg attatgtaag ctatagcaac ccaggtttgt ggggattgct
    18541 tttattgtct gtgtattagt tgcttttgcg atttttccta aaatggagaa aaattttcct
    18601 aaaactttcc tatatttcac taaatacggg aaagatagtt tagggatcta tattcttcat
    18661 gcaccaattt gtagcatgat tcggattcta atgttgaaag taggaataaa ctcagttttt
    18721 cttcacgttg ttgttgggat tgtgctaggc tggtatttat ccatactagc aacttatata
    18781 ttgaaaaaaa ttccattttt gaatattgtt ttattaccac aaaagtatat taaattaaaa
    18841 taaattattt tcggctcttt gtcaactgta gtgggttgaa aaaaagctaa gcttgagaaa
    18901 ggacaaattt tgtcctttct tttttgatgt tcagagcgat gaaaatccgt tttttgaagt
    18961 tttcaaagtt tcgaaaacca aaggcattgc gcttgataag tttgatgaga ttattggtcg
    19021 cttccagttt ggcgttagaa tagtgtagtt gaagggtgtt gacaagcttt tctttatctt
    19081 tgaggaaggt tttaaagaca gtctgaaaaa taggatgaac ctgcttaaga ttgtcctcaa
    19141 taagtccgaa aaatttctcc ggttccttat tctgaaagtg aaacagcaag agttgataga
    19201 gctgatagtg gtgtttcaag tcttccgaat aactcaaaag cttgtttaaa atctctttat
    19261 tggttaagtg catacgaaaa gtaggacgat aaaatcgctt atcactcagt ttacgactat
    19321 cctgttgtat gagcttccag tagcgcttga tagccttgta ttcatgagac tttcgatgaa
    19381 actgattcat gatttgaaca cgcacacgac tcatagcacg gctaagatgt tgtacaatgt
    19441 gaaagcgatc aagaacgatt ttagcattcg ggagtgaaac agtctgggag actgtttcag
    19501 cctgagccta gaaatttgaa agcgaagctg tttagccaag tcatagtaag gactaaacat
    19561 atccatcgta atgattttga cgcgacatcg gacggctcta tcatatttaa gaaagtgatc
    19621 tcggatgaca gcttgtgttc taccttcaag aacagtgatg atattgagat tgttaaaatc
    19681 ttgcgcaatg aagctcatct ttccctttgt aaaagcatac tcatcccaag acataatctc
    19741 aggaagacaa gaaaaatcat gtttaaagtg aaaatcattg agcttacgaa taacagttga
    19801 agttgaaatg gaaagctgat gggcaatatc agtcatagaa atcttttcaa ttaacttttg
    19861 agcaatcttt tggttgatga tacgagggat ttggtgattc ttcttgacga tagaagtttc
    19921 agcgaccatc atttttgaac agtgatagca cttgaaacga cgctttctaa ggagaattct
    19981 agtaggcata ccagtcgttt caagataagg aattttagaa ggtttttgaa agtcatattt
    20041 cttcaattgg tttccgcact cagggcaaga tggggcgtcg tagtccagtt tggcgatgat
    20101 ttccttgtgt gtatccttat tgatgatgtc taaaatctgg atattagggt ctttaatgtc
    20161 tagtaatttt gtgataaaat gtaattgttc catatgattc tttctaatga gttgttttgt
    20221 cgcttttcat tataggtcat atgggacttt ttttctacac aaaaataggc tccataatat
    20281 ccatagggga tttacccact acaaatatta tagagcctta ttttagattt ataatgtgtc
    20341 tctttgtcaa ctaacatctg gagaggacaa tcactgtctt ctcctttttt gtcttttcag
    20401 aatataccaa attaacacaa aaattctgaa aattctgttg acaactttct gaaaagagtc
    20461 tataatggag agaaagtttt aaaggagaaa atgatgaaaa gttcaaaact acttgccctt
    20521 gcgggcgtga cattattg
//
