LOCUS       GU576498               19487 bp    DNA     linear   BCT 25-JUL-2016
DEFINITION  Vibrio cholerae strain CO545 O-antigen biosynthesis gene locus,
            partial sequence.
ACCESSION   GU576498
VERSION     GU576498.1
KEYWORDS    .
SOURCE      Vibrio cholerae
  ORGANISM  Vibrio cholerae
            Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
REFERENCE   1  (bases 1 to 19487)
  AUTHORS   Aydanian,A., Tang,L., Morris,J.G., Johnson,J.A. and Stine,O.C.
  TITLE     Genetic Diversity of O-Antigen Biosynthesis Regions in Vibrio
            cholerae
  JOURNAL   Appl. Environ. Microbiol. 77 (7), 2247-2253 (2011)
   PUBMED   21317260
REFERENCE   2  (bases 1 to 19487)
  AUTHORS   Aydanian,A.G., Johnson,J.A., Tang,L., Morris,J.G. Jr., Nair,G.B.
            and Stine,O.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2010) Epidemiology and Preventive Medicine,
            University of Maryland School of Medicine, 934 MSTF, 10 S. Pine
            Street, Baltimore, MD 21201, USA
FEATURES             Location/Qualifiers
     source          1..19487
                     /organism="Vibrio cholerae"
                     /mol_type="genomic DNA"
                     /strain="CO545"
                     /serovar="O5"
                     /db_xref="taxon:666"
     gene            complement(<1..227)
                     /gene="gmhD"
     CDS             complement(<1..227)
                     /gene="gmhD"
                     /EC_number="5.1.3.20"
                     /note="LPS core biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="GmhD"
                     /protein_id="ADF80970.1"
                     /translation="MIIVTGGAGMIGSNIIKALNERGITDILVVDHLKNGRKFKNLVD
                     LQIADYMDRDDFLAQIMAGDDFGSIDAIPGGG"
     misc_feature    <1..>19487
                     /note="O-antigen biosynthesis gene locus"
     gene            447..1562
                     /gene="wzz"
     CDS             447..1562
                     /gene="wzz"
                     /note="regulates length of O-antigen component of
                     lipopolysaccharide chains"
                     /codon_start=1
                     /transl_table=11
                     /product="chain length determinant protein"
                     /protein_id="ADF80971.1"
                     /translation="MSSLANTPPVQPPQYPHYAYPANDEIDLKELFSALWQGKWLIIV
                     TTLLFSVAAIGYALTAQEWWSAKATVSQPQLQGIASYQQAVKRYQPLFDVYQEDGSII
                     VSEALDLLIDPEVIFKRFIQEFNANGTKRRFMQTNPTFLTLQKQMMEQNNDPEVMQKL
                     YEEWFERIQASAVDKKANDIFTLSFQSVDKASSLTLLNDYIQFVNQTLNQQLNANLIS
                     ILTAKYGELAQQEKNLQQQAQLRLHVELERTQYALNIAEAADIKQPVQNLGEQEIFAI
                     NIGSRALKAKVDALKSIKDLSVFEPRLAILQSKLSQFDLETLSAEAKWSVNGFYYLDQ
                     PEQPLTRDKPKRALIVVLGTLLGGMLGGGDSIDEVCV"
     gene            1669..2793
                     /gene="wecB"
     CDS             1669..2793
                     /gene="wecB"
                     /EC_number="5.1.3.14"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="ADF80972.1"
                     /translation="MPPKKVLTVFGTRPEAIKMAPLVHALAADERFEAKCCVTAQHRE
                     MLDQVLELFEITPDYDLNLMKAGQTLNEVTARILLELKPVLQEFKPDVVLIHGDTATT
                     FAASLAAYYEQIVVGHVEAGLRTGNIYSPWPEEANRKLTGALTKYHFAPTETSQQNLL
                     QENYSEENIFVTGNTVIDALLMVKEKIEQDADLKATLAAQFPYLDKSKKLILVTGHRR
                     ESFGGGFERICEALAQTAKQHPEVQILYPMHLNPNVREPVNRILGSVKNVLLIEPQQY
                     LPFIYLMDRAHIILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVAAGTVKLVGTDVEK
                     IVSNLNILLTDNKAYQAMSFAHNPYGDGKACQRILDFLCK"
     gene            2846..4111
                     /gene="wecC"
     CDS             2846..4111
                     /gene="wecC"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosaminuronate dehydrogenase"
                     /protein_id="ADF80973.1"
                     /translation="MSFETISVIGLGYIGLPTAAMFASRKKKVIGVDVNQHAVDTINQ
                     GKIHIVEPELDMMVHAAVTGGYLKATTTPEAADAFLIAVPTPFLPCVEGDIPAPDLSY
                     IQAASKAIAPVLKKGDLVILESTSPVGATEQMAAWLAEARSDLTFPQTYGEEADVNIA
                     HCPERVLPGHVVRELVENDRVIGGLTAKCSARAVELYKTFVKGECVITNARTAEMAKL
                     TENSSRDVQIAFANELSIICDKLDINVWELIALANRHPRVNILQPGPGVGGHCIAVDP
                     WFIVSKTPEEAQIIHTARKVNDSKPQWVINKVKLAIADFLQANPEKTAKEVTIACYGL
                     AFKPDIDDLRESPAMAITQKIAEMHAGRVIAVEPNIESIPEKLKHVELVGFEAASKEA
                     DIRVLLVDHKEFKVASVNSGIIIDTKGIW"
     gene            4111..5199
                     /gene="rmlB"
     CDS             4111..5199
                     /gene="rmlB"
                     /EC_number="4.2.1.46"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="ADF80974.1"
                     /translation="MKILITGGAGFIGSAVVRHIINDTQDSVVNLDKLTYAGNLESLA
                     NVAGCERYAFEQVDICERSELDRVFAEYQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTFTLLEATREYWNKLDDKAKQAFRFHHISTDEVYGDLPHPDEVADGSELPLFLETTP
                     YAPSSPYSASKASSDHLVRAWLRTYGLPAIVTNCSNNYGPFHFPEKLIPLVILNALEG
                     KQLPIYGKGDQIRDWLFVEDHARALYKVVTEGKVGETYNIGGHNEKQNLEVVQAICSI
                     LDELVPKVTPYAEQIRYVQDRPGHDRRYAINSSKMQRELGWTPIETFETGLRKTVQWY
                     LDNQQWCKNVQDGSYQRERLGTSVKGEK"
     gene            5199..6065
                     /gene="rmlA"
     CDS             5199..6065
                     /gene="rmlA"
                     /EC_number="2.7.7.24"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="ADF80975.1"
                     /translation="MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLA
                     GIREILIITTPEDQSSFKRLLGDGSDFGIELQYAIQSSPDGLAQAFIIGEEFIGKDSV
                     CLVLGDNIFYGQGFSPKLQQVTAQTIGATVFGYKVKDPERFGVVEFDSQMRVISIEEK
                     PRKPKSSYAVTGLYFYDNRVVEMAKKVKPSERGELEITTLNEMYLNDGLLNVELLGRG
                     FAWLDTGTHTSLHEASSFVETIENVQGLKVACLEEIAWRKGWLSNEQLAKAGCVLAKN
                     DYGKYLLALLEE"
     CDS             6066..6482
                     /codon_start=1
                     /transl_table=11
                     /gene="orf7"
                     /product="hypothetical protein"
                     /protein_id="ADF80976.1"
                     /translation="MKKLIRWIDFPVIGDERGNLVALEANKLIPFDIKRVYYLFGMQS
                     DLPRGFHAHRELVQVAVCIKGSCDILMDNAQEKEIVKLKSPNRGLVIDVMQWHEMNNF
                     SDDCVLLILASDYYDESDYIRSYDDFLNVLEIGNEK"
     CDS             6472..7143
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr1"
                     /product="glycosyltransferase"
                     /protein_id="ADF80977.1"
                     /translation="MKNKKLVIIGAGELARIAFEYFTYDSSYDVFAFSVNKEFIESSE
                     INGIPVVEFEELERIYPPSEYEAFVAIPATKLNRVRTRLFNEAKNKGYKLATYISSSA
                     FVWRNAEIGENCFIFENNTIQPFVKIEDNVILWSGNHIGHRTVIRANSFITSHAVISG
                     YCEIGSGSFVGVNATFNDKTSLAANSIVGSGAVVTKKLKTEEGVYIGNPAKLFPRKSA
                     FDIEL"
     CDS             7145..8074
                     /codon_start=1
                     /transl_table=11
                     /gene="orf9"
                     /product="hypothetical protein"
                     /protein_id="ADF80978.1"
                     /translation="MKWKKMGLVYRPRRKQPWNQKYAILPVPEFIENENRIRIYFGST
                     DNENFGRISYIEVDADEPTKILYEHQKPVLDLGREGTFDDCGVVPSCLVQKEECSLLY
                     TVGFQRCVKVPYMLFAGLAMFEKNEPATMKRYSEAPILERTPERPISQGAPWVLYENG
                     KYRMWHWYGTKWIEVEGKPFIDYHIGYAESDDGYTWSMTDNVCLAPIKELGEFAVARP
                     CVFKQGETYHMWYSVRLEKKMYRIAYATSKDGLKWIRHTGDFGLEVSDDGWDSEMMCY
                     PAVIEVKGRLLMFFNGNNNGETGFGVAEAELND"
     CDS             8067..9026
                     /codon_start=1
                     /transl_table=11
                     /gene="orf10"
                     /product="hypothetical protein"
                     /protein_id="ADF80979.1"
                     /translation="MTELSIRYFSEDDSIEWDSFIELSHKGTFLHSRKFLSYHGDRFV
                     DRSLIVEDRNKIVAVLPACQTYDNKSAVVSHLGATYGGLITSASCYGEDLISVMHAIC
                     VFYRNEGFSELCYKVTPSVYHNTIDEDEIYALFRLNAELVRVDNNAVVDKYSRLKVSN
                     QRKRSFKKARDANLTLFSGFENLEDFYSVLLSNLSEKHNAKPVHTISELRELKFRFNK
                     EIELVVAKNEVGYVISGVVFFNINNVVHSQYIASSSEGYDKGGLDFIFEKKIDDLLEN
                     QQRFLAFGTSNESNGKVLNQSLYRFKRQFGAGSVAHQYYSIKL"
     gene            9029..10132
                     /gene="wecE"
     CDS             9029..10132
                     /gene="wecE"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="ADF80980.1"
                     /translation="MIPFLDLKAINSQYKDKLLASCEAVIDSGFYVQGCHLREFEEKF
                     SRFCDVRHTIGVANGLDALTLTLRAWKEMGLLRDDDEVIVQANTYIATILAITENKLK
                     PILVEPCELTYNLNLKNVADAITEKTRVILPVHLYGLLSPMNEIMSLAKKHNLLVLED
                     CAQAHGAEIDGKKAGSWGDAGAFSFYPGKNLGALGDGGAVTTNSDELAKVIRSLGNYG
                     SQKKYVNEFKGVNSRLDEIQAAMLSVKLEYQDREILIRQEIAERYNREINNDNIMLPF
                     WGKKGSHVFHLYVMRVKNRDKFVDHMTNLGVQTLIHYPIPPHKQDAYSEFGNKTLPIT
                     EIIHQQVVSIPLYPTMSKEQQEIVIEAINSYKC"
     gene            10126..11367
                     /gene="wzx"
     CDS             10126..11367
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="ADF80981.1"
                     /translation="MLKFLFNKSIDSIKLGVDGLLKIITGLIVIKIISNIGDDSLLAN
                     FSQLKMLSALLISITSSAFIIGLNKLSMKYARNDFIGNMNFLIFTISVAIILVIVFFE
                     GKLSALMGRRTECFLFLSFLLLISGYLANYFLGCKIASLNNKLLSSAKIYSTTLSFFA
                     FLSVYFVGVNVWLGLYIYIISYYVFLALFLFDKNEVKNLFFSFSINVNVLKDAINIIF
                     LTFLSSVVFPSCIVYLRYDMSTLYGWEYVSFWEAEWQLSSLFLLVISPVLSVIVTTYV
                     TSKSRVGGLNKQIILKLISTIVVLAVIFSSVVYFFNELLLSTFFNSMMIVGDSSIELL
                     LLINLFRLVSVVIFYILYVISDTKKLVFGELFFLLTFALANVVLKDSQVNSSIPLLIS
                     VLICFLYFILILVKTDEYKTP"
     gene            11348..12439
                     /gene="wzy"
     CDS             11348..12439
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="ADF80982.1"
                     /translation="MNIKLPDFTFAFFLVFFLLLGKKIIDIQVVEANIFLSLFVYGLL
                     FFTSFLFLGKCILIPLLSIITLPFFLTGEFNSFGLYKIINLIFCVQVLTFVYTLLRSR
                     LQWERVFIYFSIMLAAYIIFVVLFMVLFKGWFFGQRVTMGLNGPITFSRFNFLVSLAI
                     ILFCKMKNNIIYAAPFGVVGGAMASKGPLLSLIVSLLYYYWKNITIKRVFLSIIAIYA
                     VFLSIEYFSPRLYNFLIDISKIIIEQDYSVIYSDYNSGSLGSRATEWIHAFSSFLLNP
                     MGIGAGNWSLYGEHLYPHNLFFEIITEFGFLGLLFCIVFVFSAIRVKNTELKAIILFL
                     FVNSLFSGSVVDNSLLFVLVIIGRLDSNA"
     CDS             12432..13667
                     /codon_start=1
                     /transl_table=11
                     /gene="orf14"
                     /product="WblR protein"
                     /protein_id="ADF80983.1"
                     /translation="MLDEIIFFYPSYTLGGVQTLFIRTLNKLAKEGIRVGYCDFHDGT
                     LRKSLKDNSEISYVTLDDIRNIKSNLIVTSANYMNVSKLIFHRDSKLLFWFLSPYNLP
                     ILNLSQKTNIDFKSINIIDWMYNGFENIDYLLKKESVYFMDKLCFEINGSPEVNYDSF
                     LPLYIDMPEFDASFGEDSNCLNIAWIGRIDLSVKYHCVVYLIEEFEKIKKCNKFKYVT
                     LTIVGSGAGSEDIKKMCKNLTCCDYINFIDNVEYSRFHKFIASSFDVVFAHGTTCLES
                     ASVGVPTVCLDGSINKMREGYRFKWLFKRPSYDIGRTEFDEDFSNIGSNLHDILLDVI
                     HRRSEISIKCKNVVLNSFDSSEVINKIRHAFTKANASTRDVKLNWFTFFVDLIVCRVV
                     LSKIFKIRLISLITKLNQK"
     CDS             13664..14923
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr2"
                     /product="glycosyltransferase"
                     /protein_id="ADF80984.1"
                     /translation="MNILYFHQHFSTPKGSTGIRSYEMAKRLIHHGHNVTMVCGTYGG
                     GETGLDSAFVAGKREGIVDGIRIIEFDLAYSNSDGFVKRSMTFVKFALKSIGLAFTEK
                     YDVLFATTTPLTAGIPGIFARWLRGKPFVFEVRDLWPELPKEMGVIKNPVILGLMSLL
                     EWASYRSAHRCIGLSPGIVDGIKKRGVPDNKVTMVPNGCDLSIFTQPSEPWRPDGVAE
                     EDLMAIFTGTHGIANGLGSVLNAAAELQNQGRDDIKLVLVGQGKLKPQLEAKAQELQL
                     KNVIFHPPVNKQKLAGLMASADVGMQVLANIPAFYYGTSPNKFFDYISAGLPVINNYP
                     GWLAGMIEELQCGFAVAPENPKAFANALEQAADDREALAAMGEAARQLAENRFDRQML
                     ADKWVEWVVATAQSEVKSSEVNDEKAI"
     CDS             14904..15521
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr3"
                     /product="lipid
                     carrier:UDP-N-acetylgalactosaminyltransferase"
                     /protein_id="ADF80985.1"
                     /translation="MMKRLFDFLVSLTTLILLSPIIALVAWKIRKNLGSPVFFRQTRP
                     GLNGKPFEMIKFRTMKDAVDKQGNPLPDSERMTPFGDKLRNSSLDELPELWNVLKGEM
                     SLVGPRPLLMQYLPLYSKEQARRHEVRPGVTGWAQINGRNAISWEEKFKLDVWYVDNR
                     SFWLDLRILLLTVKKVFVKEGISADGHVTIAPFTGKDQQGTGNER"
     CDS             15472..16173
                     /codon_start=1
                     /transl_table=11
                     /gene="orf17"
                     /product="putative acetyltransferase"
                     /protein_id="ADF80986.1"
                     /translation="MPHLQGKINKEQVMNVKPVSKNSLGSCAILGASGHGKVIAEMAE
                     LNGYSDIHFYDDRWPSLGRVELWQVSGNSETLLKQARNYANVVVAIGNNATRLEKYNQ
                     LVASGASCLPLVHPSAIVSRYANVENGTVVMAGAVINPFSRIGQACIINTAATVDHDC
                     VIEDGVHLSPGVHLAGGVEVAQASWLGIGCQIKQLIKIGSNAVVAAGATVINDVLANQ
                     MVVGVPAKPICSKEL"
     gene            16176..17351
                     /gene="wecE"
     CDS             16176..17351
                     /gene="wecE"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="ADF80987.1"
                     /translation="MLNTPFSPWPSFTQEEADAVSNVLLSNKVNYWTGNECREFENEF
                     ATWAGCEYAIALGNGTLALDIALKALGVGVGDEVITTSRTFLASASAIVTAGANPVFA
                     DVDLNSQNITAETIADVVTEKTKAVIVVHLAGMPAEMDAIMALAAERGFYVIEDCAQA
                     HGARYKGRSVGTIGHIGAWSFCQDKIMTTGGEGGMVTTNDHALWSLMWSYKDHGKSYD
                     AVYNRQHPPGFRWLHESFGTNWRMTEIQGVLGRIQLRRMAEWTAKRQCNGKKLDQAVS
                     DLAVVRCVQVPDYIEHAEYKHYMFINPEHLKADWSRDRIIEKINMLGVPAYQGSCSEI
                     YLEKAFDNTSWRPAQRLKNAVILGETSLMFLVHPTLTTQEIEKSCDVIRSVLTEATR"
     gene            17634..19322
                     /gene="wbfY"
     CDS             17634..19322
                     /gene="wbfY"
                     /codon_start=1
                     /transl_table=11
                     /product="putative epimerase/dehydratase"
                     /protein_id="ADF80988.1"
                     /translation="MVSVGTLISTASVAIAAFYFNAPVPRSLPIIYGTFLCLLCGGSR
                     LIVRVLVSGLNGKGRKVVLIYGAGSAGRQLAIALRNSENYKVVGFIDQDKTLENTVIM
                     GLQVYDISRAAYLVDKYDVTQVLLAVPSASRARRKKILESLIDLSAEVLTVPDMKDIV
                     EGKASIDQLKDVAIEDLLGRDPVTPQQCLMESNILGKVVMVTGAGGSIGSELCRQIVR
                     QKPKALVLFELSEFGLYQIDRELKQLMEAEGLHVEIIPLLGSVQRINRLVVTMKSFKV
                     QTVYHAAAYKHVPLVEYNVVEGVRNNVFGTYYAAQAAIEAGVESFVLISTDKAVRPTN
                     VMGTTKRMAELGLQALAEQENRKAKGTRFCMVRFGNVLGSSGSVVPLFKRQIEAGGPI
                     TVTHPDIIRYFMTIPEAAQLVIQAGAMGKGGDVFVLDMGEPVRITDLAVNLIQLSGLE
                     VKDEQHPYGDIAIEFTGLRPGEKLYEELLIGDNVQKTAHERIMTANERYLPLAEFEQH
                     LNELDKACHAFNHERIRELLLEAPTDFNPTDGIGDLVWQRTQDNQTQLEKQLVH"
BASE COUNT     5658 a   3431 c   4415 g   5983 t
ORIGIN
        1 ccccccccag gaatggcgtc aatggacccg aaatcatcac cagccatgat ctgagctagg
       61 aagtcatctc gatccatata gtcggcgatc tgtaggtcaa ccagattttt gaacttacga
      121 ccatttttca aatgatcgac gaccagaatg tcagtgatgc cacgctcatt aagcgctttg
      181 ataatgttgc tgccaatcat gccagcgccg ccagttacga taatcattat gaattcctat
      241 agatgcgaac agttgcacgc attatagcct gtcattttct tactgtaatc acaaaatcta
      301 agctccgcct tttgagggct cgccctgtaa ggggttttgg tttaaacttc gtggcaaaac
      361 gcatgttgta taacgctatt aggagcgaga cctaagggcg gtagcgtgtc aaaaaaactt
      421 gtacatctat actgcaggag caataagtga gttcattagc caatacccct cccgttcagc
      481 caccacaata cccacattat gcctatcctg ctaatgatga aattgattta aaagagcttt
      541 tttcagccct atggcaaggg aaatggctaa tcatagtgac cacattgctg tttagtgtgg
      601 ccgccatagg ttatgcatta actgcccaag aatggtggag tgccaaagca accgttagcc
      661 aaccgcaatt gcaaggtatt gctagctacc aacaagcagt aaagcgttat cagccgctgt
      721 ttgatgtgta ccaagaagac ggcagcatta ttgtgagtga ggccttagat ttattgattg
      781 atccagaggt tatttttaaa cgctttattc aagagtttaa tgctaacggc acgaaacgcc
      841 gctttatgca aactaaccct acttttttaa ctctgcaaaa gcagatgatg gagcaaaaca
      901 atgatccgga agttatgcag aagctatatg aagagtggtt tgagcgcatt caagcttcag
      961 cggtagataa aaaagctaac gatatattca ccttaagctt tcagtctgta gataaagcta
     1021 gcagcctaac cttacttaat gactatattc agtttgttaa ccaaacccta aatcagcagc
     1081 tcaatgctaa tttgattagc atcttgacgg ctaaatatgg cgagttggca cagcaagaga
     1141 aaaacttaca gcaacaagca caattacgtt tgcacgttga gttagagcgt acccaatatg
     1201 cattaaacat tgctgaggca gctgatatta aacagccagt acaaaattta ggtgaacaag
     1261 agatttttgc tattaacatt ggtagccgcg ccttaaaagc taaggtagat gccttaaaat
     1321 cgattaaaga tttgagtgtg tttgagccaa gactggcaat tttacaaagt aagctgagcc
     1381 aatttgattt agaaacgttg agtgcggaag cgaagtggtc ggtaaacggt ttctactatt
     1441 tagaccaacc ggaacaacca ttaactagag ataagcctaa gcgcgcttta attgtggtgc
     1501 ttggcacctt gctcggcggc atgttggggg ggggcgatag tattgatgag gtttgcgttt
     1561 agaagggaag aggaagttga agcgagaagc tagctagagt ggctgatggt cttctagaat
     1621 tgagcagttc taactcattt attttgataa cttaaattag gttcgacaat gcccccaaaa
     1681 aaagttctca ccgtttttgg cacccgtccc gaagcgatta aaatggcacc gttagttcac
     1741 gctttagcgg ctgatgagcg tttcgaagcg aaatgctgtg tcacagctca acatcgtgaa
     1801 atgcttgacc aagtattaga gctgttcgaa attacaccgg actacgatct aaacctgatg
     1861 aaagctggtc aaacactcaa tgaagtgaca gcgcgaattc tgttagaact aaaaccggtt
     1921 ttgcaagaat tcaaacccga tgtcgtactc attcacggcg ataccgcaac gacatttgca
     1981 gccagccttg ctgcctatta tgagcaaatt gttgttggcc atgttgaagc gggcctacgc
     2041 acaggtaaca tctactcgcc atggccagag gaagccaacc gtaagctcac gggggcgtta
     2101 accaaatacc actttgcacc aacagagacc tcccagcaaa atttgctgca agagaattac
     2161 tcagaagaga atattttcgt tacgggcaat acggtaattg atgcgctgct aatggtgaaa
     2221 gagaaaattg agcaagatgc cgatctaaaa gcaactttag cggcgcagtt cccttactta
     2281 gataaaagca aaaagctcat cttagtgact ggtcatcgcc gcgaaagctt tggtggtggt
     2341 tttgaacgta tctgtgaagc tctagcacaa acagccaaac agcaccccga ggtgcaaatt
     2401 ctctacccta tgcacctaaa ccctaacgtg cgtgaaccgg ttaatcgtat tctaggtagt
     2461 gtgaaaaatg tgctgctgat tgagccgcag caatatctgc cttttatcta cttaatggac
     2521 cgagcgcaca ttattctcac cgattctggt ggtattcaag aagaagcacc atcccttggc
     2581 aaacccgtgt tggtgatgcg cgataccacc gagcgcccag aagctgtggc tgcagggaca
     2641 gttaaattag taggaacaga tgtggaaaaa atcgtttcca acctaaacat cctgctaact
     2701 gataataaag cctatcaagc gatgagcttt gctcataacc catatggtga tggtaaagct
     2761 tgccagcgaa ttctcgattt cttgtgtaag taacttttaa gttatctcct agaaccaaat
     2821 ttataaatat tttaggacgc gtaaaatgtc ttttgaaacc atttcagtca tcggcttagg
     2881 ctacatcggc ttaccaaccg cagcgatgtt tgcatcacgt aaaaagaaag tgattggagt
     2941 agatgttaat caacacgcgg ttgataccat taatcaaggc aaaattcata ttgtagagcc
     3001 agaactcgat atgatggtgc atgctgccgt tactggtggc tacttaaaag caaccaccac
     3061 accagaagcg gccgatgcct ttttgattgc tgtgccaacg ccattcttac cttgtgtaga
     3121 gggcgatatt ccagcaccgg atctctctta cattcaagcc gccagtaaag cgattgcccc
     3181 tgtactgaaa aaaggcgact tggtgatttt agaatcgacc tctcctgttg gtgcaaccga
     3241 gcaaatggcc gcatggcttg ctgaagctcg ttctgatctt accttcccac aaacgtacgg
     3301 cgaagaagcc gacgtcaaca ttgcccattg ccctgagcgt gttttgcctg gtcatgtagt
     3361 gcgtgagctc gtagaaaatg accgagtgat tggtggttta acagctaagt gttctgcgcg
     3421 tgcggtggaa ctttataaaa cctttgttaa aggtgaatgt gttatcacaa atgcacgtac
     3481 tgctgaaatg gccaaactga ccgagaatag ctctcgtgat gtgcaaatcg cctttgccaa
     3541 cgagctatcc atcatttgtg acaagctaga tatcaacgta tgggagctaa tcgcactggc
     3601 aaaccgtcac ccacgtgtaa acatcctcca accaggccca ggtgtaggcg gccactgcat
     3661 agcagtagac ccttggttta ttgtgtcaaa aacaccggaa gaagctcaaa ttatccatac
     3721 ggcacgcaaa gtcaatgaca gcaaaccgca gtgggtgatt aataaagtga aattagcgat
     3781 tgcagacttt ttacaagcca acccagaaaa aacagcgaaa gaggtgacca ttgcttgcta
     3841 cggtttggcc tttaaacctg atatcgatga cttacgtgaa agccctgcga tggctattac
     3901 gcaaaaaatc gccgagatgc atgctggacg cgtgattgca gtagaaccca atatcgaatc
     3961 aattcctgaa aaacttaagc atgtggaact tgtaggcttt gaagctgcat ctaaagaagc
     4021 ggacattcga gtgctattag ttgatcacaa ggagtttaaa gttgcttcag taaatagtgg
     4081 catcattata gacactaagg gtatctggta atgaaaattc ttatcactgg cggcgcgggc
     4141 tttatcggct ctgcggtggt tcgtcatatc atcaacgaca ctcaagatag cgtagtaaac
     4201 ctcgataagc tcacttatgc aggtaactta gaatcactgg ccaatgttgc gggctgcgag
     4261 agatatgctt tcgagcaagt ggatatttgt gaacgctctg agctggatag agtttttgca
     4321 gagtatcaac ccgatgcagt tatgcaccta gccgctgaat cgcatgttga ccgttcaata
     4381 acagggccag ctgcgtttat cgaaactaat atagttggca cttttacatt gttggaagca
     4441 acgcgtgaat actggaacaa gctagatgat aaagcaaagc aagcattccg cttccatcat
     4501 atctcaaccg atgaagtgta tggtgacctt ccgcatccag atgaagttgc agatggttct
     4561 gagcttccac tatttttaga aacgacacca tatgcaccgt caagcccata ctcggcatca
     4621 aaagcatcta gcgatcactt agtacgagca tggttacgta cttatggttt accagctatt
     4681 gttactaact gttctaacaa ctatggtcca tttcacttcc cagaaaagct gatcccttta
     4741 gtgattctta atgcattaga aggtaagcag cttcctattt atggtaaagg tgatcaaatt
     4801 cgcgattggt tatttgttga agaccatgct cgcgcgcttt ataaagtggt aacagaaggc
     4861 aaagtcggtg aaacctacaa catcggcggt cataacgaga agcaaaattt agaagtagtg
     4921 caagcaatct gttcaattct agacgagtta gtacccaaag ttacgccata tgcagagcaa
     4981 attaggtacg tacaagatcg tcctggccat gacagacgtt acgcgattaa ttcaagtaaa
     5041 atgcaaagag aacttggctg gacaccgatt gaaacgtttg aaactgggct gagaaaaaca
     5101 gttcaatggt atctagataa ccaacagtgg tgcaaaaatg ttcaagatgg cagctaccaa
     5161 cgtgaacggt taggcacgtc agtaaaaggg gaaaagtaat gaaaggtatt attcttgctg
     5221 gtggttcagg tactcgtctc tacccgatca cgcgaggcgt ctcgaagcag ttgttgccag
     5281 tttatgataa gccaatgatt tactacccac tttcagtgct tatgctggcc ggtattcgag
     5341 aaattttaat tatcaccaca ccagaggacc aaagtagctt taaacgctta ctaggagatg
     5401 gttctgactt tggtatcgag ttgcaatatg cgattcaatc tagtccagat ggcctagcac
     5461 aagcatttat cattggcgaa gagtttattg gtaaagattc cgtgtgcttg gtcttaggag
     5521 acaatatttt ctatggccag ggtttctccc caaaacttca gcaggttact gcccaaacga
     5581 ttggtgcgac ggttttcggc tacaaagtaa aagacccaga gcgttttggt gtcgtcgagt
     5641 ttgatagcca aatgagggta atttcgattg aggaaaagcc tcgtaaacct aaatctagct
     5701 atgcggtcac agggctgtat ttttacgata accgagtggt ggaaatggct aagaaggtaa
     5761 aaccttcaga gcgtggtgag ttggaaatta caacgctgaa tgagatgtat ctaaatgatg
     5821 gtttgctaaa tgttgaatta ctaggccgag gttttgcttg gttagatacc gggacgcata
     5881 caagtctgca tgaggcatct tcatttgtgg aaaccattga gaatgttcag gggttgaaag
     5941 tcgcgtgttt agaagagatt gcatggcgca aaggatggtt gtcgaatgaa cagctggcta
     6001 aagcaggttg tgtcttggcg aaaaatgatt atggcaagta tctgttagca ttgttggaag
     6061 aataaatgaa aaagcttatt cgttggattg attttccagt cattggtgat gaaagaggaa
     6121 accttgttgc tttagaagca aacaaactca tcccttttga cattaaacgt gtttattact
     6181 tattcggtat gcagtctgat ttgccgcgtg gttttcatgc tcatagagag cttgttcaag
     6241 ttgcagtctg tataaaaggt agctgtgaca ttttaatgga taatgctcaa gaaaaagaaa
     6301 tcgttaaatt aaaatcacct aaccgaggat tagtaattga tgtcatgcaa tggcatgaaa
     6361 tgaataattt ttctgatgat tgtgtactgc ttattctagc tagtgattac tatgatgaga
     6421 gtgactacat acgtagttat gacgattttt taaatgtgtt ggagataggg aatgaaaaat
     6481 aaaaaactag tgattattgg tgctggagaa ttagctagaa tagcgtttga atattttaca
     6541 tatgattcta gttatgatgt ttttgcgttc tctgtcaata aagagtttat tgaaagcagt
     6601 gagattaatg gtattcctgt cgtagagttt gaggagttag aaagaattta cccaccaagt
     6661 gaatatgaag catttgttgc cataccggcg acaaaattga atagagtaag aacgaggtta
     6721 tttaatgaag ctaaaaataa aggctataag ctcgcaactt atataagttc aagtgcgttt
     6781 gtatggcgta atgctgagat tggtgaaaat tgctttattt ttgaaaataa cacaatacaa
     6841 ccatttgtaa aaatagaaga taatgtgatt ttatggagtg gtaaccatat tggtcatcga
     6901 acagttattc gtgcaaacag ctttattacc tcccatgctg tgatatcagg atattgtgaa
     6961 ataggttcag gtagttttgt tggagtaaat gcaacattca atgataaaac atcgctggca
     7021 gcaaactcaa ttgttggttc cggggctgtc gtaacaaaaa aattaaaaac agaagaagga
     7081 gtatacattg gaaatcctgc caaattattc cctcgtaagt ctgcatttga tatagaacta
     7141 taatatgaaa tggaaaaaaa tgggtcttgt atatagacca agaagaaagc aaccatggaa
     7201 tcaaaagtat gctattctac ctgtgccgga atttattgag aatgaaaata ggattcgtat
     7261 ttattttggt tcgacagata atgagaattt tgggcgaata tcttatattg aagtagatgc
     7321 agatgagcca actaagatac tctatgagca tcaaaagcct gtattggatc taggtagaga
     7381 aggtacattt gacgattgtg gtgtagtacc ttcctgttta gttcaaaaag aagagtgctc
     7441 attgctatat acagtgggtt ttcagagatg cgttaaagtg ccgtatatgt tgtttgctgg
     7501 tttggcaatg tttgaaaaaa atgaaccagc aacgatgaag agatattctg aagctccgat
     7561 attagagaga actccagaga ggccaatttc tcaaggggct ccttgggttt tatacgagaa
     7621 tggtaaatat cgtatgtggc attggtatgg gactaagtgg atagaagtcg aagggaaacc
     7681 attcatagac tatcatattg gatacgctga gtccgatgat ggttatactt ggtcaatgac
     7741 tgataatgtg tgtctagctc caataaagga acttggtgag tttgctgttg cgagaccctg
     7801 cgtatttaag caaggtgaaa cataccatat gtggtattcc gtgagattgg aaaaaaaaat
     7861 gtacaggatt gcatatgcaa catccaaaga cggtttaaag tggataaggc atacaggtga
     7921 ttttggatta gaagtttccg atgatggttg ggatagtgaa atgatgtgtt atccggctgt
     7981 aattgaagtg aagggaaggt tgttaatgtt ttttaatggt aacaataatg gagaaacagg
     8041 ctttggtgta gctgaggctg aattaaatga ctgaactatc aattcgctac ttctcagaag
     8101 atgatagcat tgaatgggat agctttattg agctctcgca taaagggact tttctacact
     8161 ccaggaaatt tctaagttat catggtgacc gatttgtaga tcgctctttg atagtggaag
     8221 ataggaataa aatcgtcgct gttttaccag catgtcagac ttatgataac aaatctgctg
     8281 tagttagtca tttaggtgca acttatggag gtctcataac ttctgcatcg tgctatggtg
     8341 aagacttaat ttcagtaatg catgctattt gtgtttttta tcgtaatgaa ggctttagtg
     8401 agctttgtta taaagttaca cctagtgttt atcataatac aatcgatgag gatgagatct
     8461 atgctctatt taggttgaat gccgaacttg ttcgagtgga caataacgca gttgttgata
     8521 aatattctag attaaaagtg agtaatcaga ggaaaagatc ttttaagaaa gcaagggacg
     8581 ctaatttgac gttattcagt ggatttgaaa atcttgaaga tttttactcg gtgctactaa
     8641 gtaatttgtc agaaaaacac aatgctaagc ctgttcatac tatttccgag ctacgtgaat
     8701 taaagtttcg tttcaacaaa gagattgagc tggtagtagc caaaaacgaa gttggttatg
     8761 tcatttcagg agtggtcttt tttaacatta ataatgtagt gcattcacag tatattgcct
     8821 catcaagcga gggatatgat aaaggtggat tggattttat ttttgagaaa aaaattgatg
     8881 atctcttaga aaatcaacaa aggtttttgg catttggtac atcgaacgaa agcaacggta
     8941 aagtcttaaa tcaaagctta tatcggttta aacgacaatt cggggctggc tctgtagccc
     9001 atcagtatta ttcaataaag ttatagctat gatcccattt ttagatttga aggcgataaa
     9061 ctcgcagtat aaagataagt tattagcctc ttgtgaggct gtaattgatt caggttttta
     9121 tgttcaagga tgtcacttac gagaatttga ggaaaaattt tccaggtttt gtgatgttag
     9181 gcatactata ggtgtcgcta atggtctgga tgcgttaaca ttaactttaa gagcttggaa
     9241 agaaatgggt ttattgcgtg acgatgacga agttatcgtt caggctaata catatattgc
     9301 tacgatttta gctattacag aaaataaatt aaagcctatt ttggttgaac cttgtgaatt
     9361 gacatataat ctgaatttga aaaatgttgc tgatgcaatt acagaaaaaa caagagtaat
     9421 attacctgtg catttgtatg gattattgag tcctatgaat gaaattatgt cattggctaa
     9481 aaagcataat ttattagtat tagaagattg tgcgcaagca catggtgccg agattgatgg
     9541 taaaaaagct ggctcctggg gggatgctgg agcatttagt ttttatcctg gcaaaaactt
     9601 aggtgcatta ggtgatggtg gtgcagttac tacaaatagt gatgagctag caaaagttat
     9661 tcgtagttta ggtaattatg gtagccagaa aaaatatgtg aacgaattta agggagttaa
     9721 ttcgcgccta gatgagattc aagctgcaat gcttagcgtt aagctagaat atcaagacag
     9781 ggaaattcta atacgacagg aaatagcaga acgttataat cgtgaaatta acaacgataa
     9841 tataatgcta cctttttggg gtaaaaaagg tagccatgtt tttcacttat acgtaatgcg
     9901 tgttaagaat cgagataaat ttgtggatca tatgactaac cttggagttc aaacgttgat
     9961 tcactatccc attccgccac ataaacaaga cgcttactcc gaatttggga ataagactct
    10021 accaatcaca gaaattattc atcaacaagt agtatcaatt ccactgtatc ctactatgtc
    10081 taaagaacaa caggaaatag tgatagaggc tatcaatagt tataaatgtt aaaattcttg
    10141 ttcaataaat ctatagattc aattaagttg ggtgtagacg ggcttttaaa gataataact
    10201 ggtctaatag tcattaaaat catctccaat attggagatg attcactttt ggctaacttt
    10261 agtcagttga aaatgctatc agcactgcta atatctatta cctctagtgc attcatcatt
    10321 gggctaaaca aactttcaat gaaatatgca aggaacgatt tcattggaaa tatgaacttc
    10381 cttattttta ccattagtgt agcaattatt ctggtgattg ttttttttga aggtaagcta
    10441 agcgctttaa tggggcggcg tacagaatgc tttttatttc tatcttttct tttattgatt
    10501 tcaggctatc ttgctaacta ttttttaggt tgtaagattg cgtccttgaa taataaattg
    10561 ttgtctagtg ctaaaatata ttctacaacg ctttcttttt ttgcatttct ttctgtttac
    10621 ttcgttggtg tgaacgtatg gcttggttta tatatatata taatttctta ttatgtgttt
    10681 ttagctttgt ttttatttga taaaaatgaa gttaagaacc tgtttttttc attttcaatt
    10741 aacgttaatg tattgaagga tgcaattaat attatatttt tgactttttt atcatctgtt
    10801 gtttttccgt cgtgtattgt ttatctgaga tatgatatgt caaccttgta tggatgggag
    10861 tatgtatcct tttgggaggc tgagtggcaa ctttcttcat tgtttttatt agtaatttct
    10921 cctgttttaa gtgttattgt tacaacatat gtgacatcaa aatcgagagt tggtggatta
    10981 aataaacaaa tcattttgaa actcatctca acaatcgtag tgctagcagt gattttttca
    11041 tcggtagtgt atttttttaa tgagcttctt ttgtctacat tttttaactc aatgatgatt
    11101 gtaggtgatt catctattga gctgttactt ttaattaatt tgtttagatt agtttctgtt
    11161 gttattttct atatacttta cgtaataagc gacaccaaga agctggtttt tggtgagttg
    11221 ttttttcttt tgacttttgc tctggctaat gttgtcctta aagattcaca ggtaaactca
    11281 agcatacctt tacttatttc tgtattaatt tgttttttgt attttatttt aatcttggtt
    11341 aaaacagatg aatataaaac tccctgattt tacctttgct ttttttcttg tttttttcct
    11401 acttttagga aaaaaaatca tcgatatcca agttgttgag gctaatatat tcctgtctct
    11461 atttgtttat ggcttgcttt tttttacgtc ctttcttttt ttagggaagt gtatactcat
    11521 acctttactc tcgataatta cgcttccatt ttttttaact ggagagttta atagttttgg
    11581 tttatataaa ataataaatc taattttttg tgtacaagtg ctgacatttg tatacaccct
    11641 tctgagaagt agacttcaat gggaaagagt atttatttat ttttcaatca tgctggcagc
    11701 ttatatcatt ttcgttgttt tgtttatggt tctttttaag gggtggtttt ttgggcagag
    11761 agttacaatg ggtcttaatg gtcccattac attttcgaga tttaattttc tagtttctct
    11821 ggcaataatt cttttctgta aaatgaaaaa caacataata tatgctgctc cttttggtgt
    11881 tgtgggggga gcaatggcat cgaaagggcc actattgagt cttatcgtct cgttgctcta
    11941 ttactattgg aaaaacataa caattaaaag agtatttttg tcaataattg cgatttatgc
    12001 cgtattttta tcaattgagt atttttctcc aaggctttac aattttctca tagatatatc
    12061 gaaaattata attgagcaag attattctgt aatatactca gactataatt ctggcagtct
    12121 tggctctaga gctacggaat ggatacatgc tttttcatca ttcttattga atcctatggg
    12181 aataggtgct ggtaactggt cactatatgg tgagcatctt tatcctcata accttttttt
    12241 tgagattata acggagtttg gctttttagg gcttcttttt tgtattgttt ttgtctttag
    12301 tgccatccga gttaagaaca ccgaactaaa agctataatt ctattcttgt ttgttaactc
    12361 tctttttagt ggttcagttg tagataactc gctactattt gtattggtaa taattggtag
    12421 gctagatagt aatgcttgat gaaataattt tcttttatcc ttcatatact ttaggtgggg
    12481 ttcaaactct ttttataaga actttaaaca aattagctaa ggaaggaata agggttgggt
    12541 attgtgactt tcatgatgga actcttagga aatctctaaa agacaattcg gaaatatcat
    12601 atgtgacctt agatgatatt agaaatataa aatcaaattt aatagttact agtgctaact
    12661 atatgaatgt aagtaagctg atttttcatc gagactcaaa gttgttgttt tggtttttat
    12721 ctccttataa tcttcccatt ctaaatttat cccaaaagac caatatagat tttaaaagca
    12781 taaatattat tgactggatg tataatggct ttgaaaatat agactatctt ttaaaaaaag
    12841 agtcagttta ttttatggat aagctgtgtt ttgagattaa tgggtctcca gaagtaaatt
    12901 atgactcctt tttgccactt tacatcgata tgcctgaatt tgacgcaagt ttcggtgagg
    12961 atagtaattg cttaaatatc gcatggatag gtagaataga tttatcagtt aaatatcact
    13021 gtgtagttta cttaattgaa gaatttgaga aaattaaaaa atgcaacaag tttaaatatg
    13081 tgacactgac cattgtaggt tcgggggctg ggtctgaaga tataaagaaa atgtgtaaaa
    13141 atttgacttg ttgtgattat atcaatttta ttgataatgt tgaatattca aggtttcata
    13201 agttcattgc ttcaagcttt gatgtggttt ttgctcatgg aacaacttgc ttagaatctg
    13261 catccgttgg ggttccaacg gtatgtcttg atggttctat aaataaaatg cgcgaaggct
    13321 atcgttttaa atggctcttc aagagaccat cttatgatat cgggagaaca gagtttgatg
    13381 aggatttttc aaatattggc tctaatttgc atgatatctt gctagatgtg atccacaggc
    13441 gtagtgaaat ttcaataaag tgtaaaaatg tggttttaaa tagctttgat tcaagtgaag
    13501 taataaataa aattcgacac gcttttacta aagcgaacgc tagtactcga gatgttaagt
    13561 tgaattggtt tacttttttt gttgatctca tagtttgtag ggttgttttg tctaaaattt
    13621 ttaaaattag attaattagc ttaataacaa agttgaatca gaaatgaata ttctttattt
    13681 tcaccagcac ttttcaacac cgaaaggttc tactggaata cgttcatacg agatggcaaa
    13741 gcgccttata catcatgggc ataatgtcac tatggtatgt ggtacctatg gtggtgggga
    13801 aacggggtta gactcggctt ttgtggctgg taagcgcgaa ggtatcgtcg atggcattcg
    13861 tattatcgag tttgatttgg cttactccaa ctcagatggc tttgttaaaa gaagcatgac
    13921 gtttgttaag tttgcactca aaagtatcgg cttagctttt acggaaaaat acgatgtatt
    13981 gtttgcaaca acaacgcctt taacagcggg tattccgggc atttttgcac gttggctacg
    14041 tgggaaaccg tttgtatttg aagtaagaga tttgtggcct gaattaccaa aagaaatggg
    14101 ggtaatcaaa aaccctgtca ttttgggttt gatgtctcta ttagagtggg cttcttatcg
    14161 gagtgcacat cgatgtattg gtctttcccc tggcattgtg gatggaatta agaaacgagg
    14221 tgtaccggac aacaaggtta ccatggtacc caacggttgt gatctgtcta tctttaccca
    14281 gccaagcgaa ccgtggagac cagacggagt ggctgaagaa gatctgatgg ctatttttac
    14341 tggtacacat ggtatagcga atggcttggg ctctgttctg aatgcagcgg cagagttaca
    14401 aaaccaaggt cgagacgata ttaagctcgt tttggtaggg caaggtaagt taaaaccgca
    14461 actggaagca aaagcgcaag agttacaact caagaatgtc atctttcatc ccccagtgaa
    14521 taaacaaaag ttagcggggt taatggcaag tgccgatgta ggtatgcagg tattggccaa
    14581 tattccggct ttttattacg gaacatcgcc aaataagttc ttcgattaca tatctgcggg
    14641 actgcccgtt ataaataact acccaggttg gcttgcaggc atgattgaag agttgcagtg
    14701 tggctttgct gttgctccag aaaaccctaa agcctttgcg aacgcactag agcaggctgc
    14761 ggacgaccga gaagctcttg ctgcaatggg agaagcagct cgacaacttg ctgaaaatcg
    14821 gtttgatcgt cagatgctag ccgataaatg ggttgagtgg gtagtagcaa cggctcagtc
    14881 agaagtgaaa tcttcagagg taaatgatga aaaggctatt tgattttctg gtttcactta
    14941 caacgcttat cctgctctca ccgataattg cgctggtcgc gtggaaaatc cgcaaaaacc
    15001 ttggctcgcc agtttttttt cgtcaaacac gccctggctt aaacggcaag ccctttgaaa
    15061 tgatcaaatt tcgtactatg aaagacgccg tagacaaaca aggtaaccca ttgccagatt
    15121 cagagcgcat gactcctttc ggtgacaagt tgcgtaattc aagcctagat gaattgccag
    15181 aactctggaa tgtgcttaaa ggtgagatga gcttggttgg tcctcgtcca ttgctaatgc
    15241 aatatttacc tctgtatagc aaagagcaag ctcgtcggca tgaagtccgt cctggggtaa
    15301 ctgggtgggc acaaattaat ggtcgtaacg ccataagttg ggaagaaaaa ttcaaactcg
    15361 acgtttggta tgtggataat cgctcttttt ggttagattt aagaattctg ttgttaacag
    15421 taaaaaaggt gtttgttaaa gaaggtattt cggcggatgg tcacgtcacc attgccccat
    15481 ttacagggaa agatcaacaa ggaacaggta atgaacgtta agcctgtgag taaaaactcg
    15541 ttaggttctt gtgcaattct cggtgccagc gggcatggca aggtgattgc tgaaatggct
    15601 gagctcaatg gctattctga tatccatttt tatgatgacc gctggccaag tctaggacga
    15661 gtagagcttt ggcaggtgtc aggcaatagt gaaaccttac tcaagcaagc gcggaattat
    15721 gctaatgttg ttgttgctat aggcaataac gcaactcgct tagagaagta caatcaacta
    15781 gttgcgtctg gagctagctg tctgccttta gttcatccct cagccatagt tagtcgatat
    15841 gccaatgtgg aaaatggtac ggtagtgatg gctggtgcgg tgattaaccc gtttagccgt
    15901 atcgggcagg cctgcattat taatactgcc gctacggtag atcacgattg tgtgattgag
    15961 gatggagtgc atctgagccc tggtgtacac cttgccggcg gtgtagaagt cgcacaagct
    16021 agttggctgg gaattggttg tcagattaag caattaatca aaattggttc aaacgctgtt
    16081 gttgcagcag gagcaacagt gataaacgat gtattagcga atcagatggt ggtaggtgtc
    16141 cctgcaaaac ctatttgctc taaggaatta taactgtgtt aaatacccct ttttctcctt
    16201 ggccgagttt cactcaagaa gaggctgatg cagtaagtaa cgtgctgctt tctaacaaag
    16261 tcaattattg gacgggtaac gagtgccgtg agtttgaaaa tgaattcgcg acatgggcag
    16321 gttgtgaata cgctattgct ttgggtaacg gcactttagc gcttgatata gccttaaaag
    16381 cgttgggtgt tggtgtgggt gatgaagtga tcacgacttc gcgcactttt ttggcctctg
    16441 cttctgcgat tgtcactgct ggtgccaatc ctgtgtttgc tgatgttgat ctcaacagcc
    16501 aaaatattac tgctgaaacc attgcggacg tagtcactga aaaaaccaaa gcagtaattg
    16561 tggttcattt agctggtatg cctgcggaaa tggatgcgat catggcgctc gccgctgagc
    16621 gcggttttta tgtgattgaa gattgcgccc aagcacatgg tgcgagatac aaaggccgca
    16681 gtgtcggcac cattgggcat attggtgctt ggtccttctg ccaagataaa attatgacta
    16741 ctggtggtga aggcggcatg gtgacgacaa atgaccatgc gctttggtcg ctgatgtggt
    16801 cctacaaaga tcatggtaaa agctatgatg ctgtatacaa tcgtcagcac cctccgggct
    16861 ttcgctggtt acatgaaagc tttggtacta actggcgtat gactgagatc caaggagtat
    16921 tgggcagaat tcagctccgg cgtatggctg agtggacagc aaagcgtcaa tgtaatggta
    16981 agaagcttga ccaagctgta tctgatttag ctgtcgtacg gtgtgttcaa gtaccagact
    17041 atattgagca tgcagaatac aaacattaca tgttcattaa tcctgagcat ctgaaagcag
    17101 attggagccg tgaccgtatt atcgaaaaaa ttaatatgtt aggtgttcct gcttatcaag
    17161 gtagttgctc tgagatttac ttagagaagg cgtttgacaa tacatcttgg cgtccagctc
    17221 aacgacttaa gaatgcggtt attttgggag aaactagcct tatgttttta gtccatccca
    17281 ctttgactac ccaagaaata gagaaaagtt gtgatgttat taggagcgtt ttaaccgaag
    17341 caacgagata aaataataat gaaatattca aaggctaata catggctagg ctaaacttta
    17401 tctggaatct ttcgcgtgta aataagcgca tcatcagtgt tttggttgat gcgtttttta
    17461 tcattttctc attttacagt gcttactggg ttcgagtcgg gaactttgag attattcact
    17521 cagactcgat agcctacctt cttactacgg ttatcgttgt tacaattcta agttttactc
    17581 gacttgggtt gtatcgagct atcctacgtt acctcacttt ccatgctctt gctgtggtga
    17641 gtgttggtac cctaatctct acagcatctg ttgctattgc cgctttttat tttaatgcac
    17701 cagtgccgcg ttctttgcct atcatctatg gcaccttttt gtgcctgttg tgtggtggat
    17761 cgcgcctaat tgtgcgtgta ttggtttctg ggctcaatgg caaaggtcgt aaagtcgtgc
    17821 tgatttatgg cgcgggctct gctggtcgtc aactagcgat agctttacgt aactcagaaa
    17881 actacaaagt ggttgggttt atcgatcaag ataaaaccct tgaaaatacc gtaatcatgg
    17941 gtttgcaagt ctatgatatt agccgagctg cttacctcgt tgataagtac gatgttaccc
    18001 aagtgctact tgcagtaccg agtgcttcac gagcgcgtag gaagaagatt ctcgagtcat
    18061 tgatagactt gtcggcggaa gtgcttacgg ttcctgatat gaaagatatc gttgaaggca
    18121 aggcatccat cgatcagttg aaagatgtgg cgattgaaga cttactgggg cgcgatccgg
    18181 tgacacctca gcaatgttta atggaatcga atatcttagg taaggtcgtc atggtgactg
    18241 gggctggcgg ttctatcggc tccgagctct gtcgtcagat tgtgcggcaa aaacctaaag
    18301 cacttgtgct gtttgagctt tctgagtttg ggttatacca aatcgataga gaactcaaac
    18361 aactgatgga agccgagggt ctgcatgttg aaatcatccc gttactagga tcggtacaga
    18421 gaattaatcg ccttgtggta acgatgaaaa gcttcaaggt tcaaactgtg tatcatgctg
    18481 ctgcttataa acatgtacct cttgttgagt acaatgtcgt tgaaggggta cgcaataacg
    18541 tttttggtac ttactacgct gcgcaggcgg ccattgaagc aggtgttgaa tcgtttgttc
    18601 tgatctccac tgataaagcg gtgcgcccga ccaatgtcat gggaaccacc aagcgtatgg
    18661 ccgaactggg tttgcaagcg cttgcggaac aagaaaaccg taaagccaaa ggaactcgct
    18721 tttgtatggt gcgttttggt aatgttttgg gctcatcggg ttctgtggtt ccgctgttta
    18781 aacgtcaaat tgaggcaggc ggcccaatta cggtgacgca cccagacatt attcgttatt
    18841 tcatgaccat ccctgaagcg gcgcaactgg tgatccaagc cggagctatg ggtaaaggtg
    18901 gggatgtgtt tgtgcttgat atgggtgagc ctgtgcgcat cactgacctc gcggttaacc
    18961 ttattcagct ttctgggctg gaagtgaaag atgagcagca tccttatggg gatattgcta
    19021 ttgagttcac agggttaagg ccaggtgaga agctctatga agaactgctg attggcgata
    19081 atgttcaaaa aacggctcat gagcgaatca tgacagccaa tgaacgttat ttacctttag
    19141 cggaatttga acagcatctt aacgagctag acaaagcgtg tcatgcattt aaccatgagc
    19201 gtatccgtga gctactgctt gaagcaccga ccgattttaa tccgacagat gggattggcg
    19261 acttagtttg gcagcgtacg caagataacc aaactcagct cgaaaaacag cttgtgcatt
    19321 aatgatgtcg atttaagttg aaaaaccgcg gtctctaccg cggttttttt attctttcga
    19381 ttcatgcttg agcgaaatag gtatgatccc atcggttgat taatgtactc aggagtggaa
    19441 aacaacatgg aagtggttca tcacggaggg aaggcgagtg tcacggg
//
