LOCUS       GU576499               26128 bp    DNA     linear   BCT 01-APR-2011
DEFINITION  Vibrio cholerae strain CO845 O-antigen biosynthesis gene locus,
            partial sequence.
ACCESSION   GU576499
VERSION     GU576499.1
KEYWORDS    .
SOURCE      Vibrio cholerae
  ORGANISM  Vibrio cholerae
            Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
REFERENCE   1  (bases 1 to 26128)
  AUTHORS   Aydanian,A., Tang,L., Morris,J.G., Johnson,J.A. and Stine,O.C.
  TITLE     Genetic Diversity of O-Antigen Biosynthesis Regions in Vibrio
            cholerae
  JOURNAL   Appl. Environ. Microbiol. 77 (7), 2247-2253 (2011)
   PUBMED   21317260
REFERENCE   2  (bases 1 to 26128)
  AUTHORS   Aydanian,A.G., Johnson,J.A., Tang,L., Morris,J.G. Jr., Nair,G.B.
            and Stine,O.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2010) Epidemiology and Preventive Medicine,
            University of Maryland School of Medicine, 934 MSTF, 10 S. Pine
            Street, Baltimore, MD 21201, USA
FEATURES             Location/Qualifiers
     source          1..26128
                     /organism="Vibrio cholerae"
                     /mol_type="genomic DNA"
                     /strain="CO845"
                     /serovar="O8"
                     /db_xref="taxon:666"
     misc_feature    <1..>26128
                     /note="O-antigen biosynthesis gene locus"
     gene            119..229
                     /gene="gmhD"
     CDS             119..229
                     /gene="gmhD"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-L-glycero-D-mannoheptose-6-epimerase"
                     /protein_id="ADF80989.1"
                     /translation="MIDDQNVSDATLIKRFDNVAANHASAASYDNHYEFL"
     gene            434..1558
                     /gene="wzz"
     CDS             434..1558
                     /gene="wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="chain length determinant protein"
                     /protein_id="ADF80990.1"
                     /translation="MSSLANTPPVQPPQYPHYAYPANDEIDLKELFSALWQGKWLIIM
                     TTLLFSVTAIGYALNAQEWWSAKATISKPQLQNITAYQQAVKRYQPLFDVYQEDGTVI
                     VSNTLDRLIDPKLIFQEFIQTFNANGTKRRFMQTNPTFLTLQKQMLDQTNAPETMQKL
                     YEAWFERIQASAVDKNNDTFTLSFQSVDKASSLTLLNEYIQFVNQTLSQHLNDDFVST
                     LASKYGELAQQEKSLLQQAQLRLQVELERTQYALNIADAADIKLPVQNLGEQELFAIN
                     IGSRALKAKVDALKSIKDLSVFEPRLAILQSKLSQFDLETLSAETKWSVNGFYYLDQP
                     EQPLTRDKPKRALIVVFGGLLGGMLGVAVVLVRFTFRRDD"
     CDS             1702..2751
                     /EC_number="1.1.1.18"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf3"
                     /product="myo-inositol 2-dehydrogenase"
                     /protein_id="ADF80991.1"
                     /translation="MIKMIKNRKIRIAVVGCGRISKNHFGSIEQLDSEYELVAVCDNN
                     PEVLELHSNKYGVPGYHSIDDLLASQTLDIVTLCTPSGIHAPQTIKAAKAGIHVITEK
                     PMATKWEDGLAMVKACDEAGVRLFVVKQNRRNSTLQLLKRAVTEKRFGKIHMVHLNVF
                     WTRPQEYYDRAAWSGTWHMDGGAFMNQATHYVDLLHWLVGPIETIHAMTSTHRDIEVE
                     DTGVVNIKWRNGALGSMAVTMCTYPNNLEGSITILGEKGTVRVGGVAVNQIQEWNFAE
                     SKDYDQQIEQANYQTTSVYGFGHPPYFKNVADVLRGEAEPETDGREGLKSLELLISIY
                     RSARDHKEIGLPLNL"
     CDS             2768..4042
                     /codon_start=1
                     /transl_table=11
                     /gene="ugd"
                     /product="UDP-glucose dehydrogenase"
                     /protein_id="ADF80992.1"
                     /translation="MKLENLNIGIIGLGYVGLPLAVEFGKKFNTVGFDINQKRVAELR
                     SGVDLTLECSEEELRSAPLLSYTHQLEEIKDCNFYIVTVPTPITDEKTPDLNPLKKAS
                     EALAKVISHGDVVVFESTVYPGATEEVCLPIIEKNSGLVFNRDFFAGYSPERINPGDK
                     VNRLTTIMKITSGSTPEVADFVDQVYASIVTAGTHKAPSIKVAEAAKVIENTQRDLNI
                     AVINEFAKIFNRLGIDTEAVLKAAGTKWNFLHFKPGLVGGHCISVDPYYLTHKAQEVG
                     YRPEVILAGRRINDGMGEYVATQLVKALSRKKIHIDEAKVLIMGFTFKGDCPDVRNTK
                     IIDIVNELQDFNMSVDVYDSWASKEEVKHEYGIELIDELRDGYYDAIVLAVDHSQTKQ
                     MGVEKLRRLGKKEHVLYDVKHVLTADEADIRL"
     CDS             4230..4820
                     /EC_number="2.3.1.89"
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr1"
                     /product="glycosyltransferase"
                     /protein_id="ADF80993.1"
                     /translation="MKYFKHETAIIDDGAQIGDGSRVWHWAHVCAGAHIGQGVSLGQN
                     VFVGNKVTIGDHCKIQNNVSVYDNVHLEEGVFCGPSMVFTNVYNPRSMIERKDQYRDT
                     LVRKGATLGANCTIVCGVTIGEFAFIGAGAVVNKDVPAYAMMVGVPAKQKGWMSEFGE
                     QLDLPLSGDAEVICPHTGAVYTLSGDTVIKNIGANK"
     gene            4887..5966
                     /gene="wecE"
     CDS             4887..5966
                     /gene="wecE"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase"
                     /protein_id="ADF80994.1"
                     /translation="MQFIDLGAQQARIKEKIDVGIQKVLAHGQYILGPEVAELEQKLI
                     AYTGAKHCISVANGTDALQIAQMALGVGPGDEVITPGFTYIATAETVALLGAKPVYVD
                     VCPKTYNLDPTKLEAAITPRTKAIIPVSLYGQCADFDAINTIAAKYGIPVIEDSAQSF
                     GASYKGKKSCNLSTIACTSFFPTKPLGCYGDGGAIFTNDDELALVMRQIARHGQDRRY
                     HHIRVGINSRLDTLQAAILLPKLEVLHEEIELRNQVANTYTRLLNNAGILSTPFVEAH
                     NISAWAQYTIRVKYRAEIQHKLQEAGIPTAVHYPIPLNKQPAVADRSIQLPIGDEIAE
                     EVMSLPMHPYLTEQDIQRVVESLAQ"
     misc_feature    5963..6235
                     /note="similar to O-antigen acetylase"
     gene            6241..7296
                     /gene="wzx"
     misc_feature    6241..7296
                     /gene="wzx"
                     /note="similar to flippase"
     CDS             7315..9105
                     /EC_number="6.3.5.4"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf7"
                     /product="asparagine synthetase"
                     /protein_id="ADF80995.1"
                     /translation="MCGIAGYIFSGVLDKSNLKKMTDSIIHRGPDGEGHYYGDGFFFG
                     HRRLAIVDLTEHGKQPMLYQDRYIITFNGEIYNYIEIKKELIDVGYRFNNDTDTEVIM
                     AAYDYWGVNCLDRFNGMWAFVLYDKKEDVFFISRDRFGKKPLYYSLDNNKFVFCSEVK
                     GLYASGLVEKAPNKSYLKNYVENGPNEYDAETAFANVYRFPFAHYFLGSKEQLLNQPK
                     FTRYWELTTNTSKERFCPSKAKEYAKQYYDLLADAVRLRLRADVKVGSALSGGLDSSS
                     IVYLVNEQLRAQGKADLQETFSSVYKSDGTQNCDESVYIDLLAKALNVNSNQIEPQEG
                     DIPVEHQKMIWAMENPPESTCMSGWHTFIKVKESGVKVTLDGQGADEQLAGYLPYIAS
                     YLTSISLIDLYKEFFYFLKIPGAKKTLLFSFLMANFKFIFGMKAYQALFKKIKGRQPP
                     TELNLELKSAIEKGLINLIHYSDRVSMGHSIESRMPFMDYRLVEFLAQVPACYKMHNG
                     WTKYLARLAFDKKLPDEITWRKDKMGWPIPEEHWFRGNLRLWASDTLMNSKVLKEISP
                     ELDAETEFKSNIKKSIRKLNIATINKLNFW"
     CDS             9113..10069
                     /EC_number="2.1.2.9"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf8"
                     /product="formyl transferase"
                     /protein_id="ADF80996.1"
                     /translation="MRILIITSGLTRIVSPVLDSGHEILGIVESMPRGWSEKQEKPFL
                     FQFAQKIHRIFLGRKKTLKQFCEIRNIRYNYISKGRDAEVTNWVKELNPDLIVVFSMS
                     QLLKKDLIDIPKYGVINLHPSMLPEYRGPNPDFWQYYNMEMNPGVTVHYIDEGEDTGD
                     IIFQERVHIPLGIKSPERLDKLIGGVGSSLLVKAIQAIKSGSAPRIPQPSHSSTLRAR
                     NLKSEEHKEIIDWQNWPIERIWHVLRGTELWLNAYDQPKGIFKGQRWVVGEYERKDNI
                     DLPGAIVRYKGRKALATPDGYIFIDINFSLKKALLFVLNFKF"
     CDS             10066..11040
                     /codon_start=1
                     /transl_table=11
                     /gene="orf9"
                     /product="conserved hypothetical protein"
                     /protein_id="ADF80997.1"
                     /translation="MSESMINKEKYRQLCEEEPTIPIFSQAWWLDAVARDNWDVCIVE
                     KGDKIQATMPYIIQKKFGLTLLTQPKLTQTLGPWLRPSTAKYSKQLSQQKDLMEALID
                     QLPKYHYFSQNWHYSNTNWLPFYWKGFEQITRYTYLIDDLSNIDDVWDSSLANIRTDI
                     RKAENKFNLVVKENLPFSDFLLLNRQTFLRQGMQLPYSESFVNQLVFTAKDRNQCRWF
                     IAQDNEGRNHAGVLLVWDSESAYYLMGGGDPDLRNSGATSLCMWEAIKFASTVTKRFD
                     FEGSMIEPVERFFRAFGAKQTPYFALTHRPSRWLNTAIHFKKALKGQA"
     CDS             11120..12475
                     /codon_start=1
                     /transl_table=11
                     /gene="orf10"
                     /product="polysaccharide deacetylase"
                     /protein_id="ADF80998.1"
                     /translation="MIHFSDGAIRWLETILFERFGHRFILAEQPNTLQFYLNDSQGSI
                     AFPSLQGIFHQSRSDFPCQQWQASSEDFIAPIEDYIPAPFLNALPSPLIEFTEQGAIV
                     HYDILGLTYWVLTRLEEVGRKDLDNHQRFPAVSSHAYQHGYLERPIVDEWLMILGQVI
                     QRVWPDIELKQHEFSIKVSHDVDSPSMYGFKPWPTIGRMMAGHLLKRRDLKAFFTAPY
                     VKLATHSQLHPTDPYNTFEWLMDISEANNIKSAFYFICGGNHSHDADYEPEHPAIRNL
                     MRRIHERGHEIGLHPSYGTFQQPELIKQEAERLKRICAEESIEQQLWGGRMHYLRWEQ
                     PTTMRAWAGAGMTYDSTLGYADRPGFRCGTCYEYPAFDPVAHEQLNLRIRPLAVMECT
                     VIDAVYLGLGVTEAAEEKIQQLKMRCQQVSGTFGLLWHNSYFKNSNLRNIYKNVLGSQ
                     L"
     gene            12472..13812
                     /gene="wzy"
     CDS             12472..13812
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="ADF80999.1"
                     /translation="MRFIPYNKVIVLKIIIILQLTTLLIYLNANIVNVGEMGVALHLL
                     VEFVGLTSLLFAMFWVKKKLYFHIHFFFFLLLICWIAFRIVFDLNDLEYLKQLTVATT
                     GGVLLFYIIGASLGLTRHSLASLRSDIKIEKYIILLFYFLSIWMLYNFSQRLHDSLFY
                     LKDIDGSYQRSGNFLSISFIIISFAYLNLVLKNVAQGATILARFFWLFVYTLSTLMAL
                     VGSQLFGSNSATAVILGVYLITLVMSLVTAKKTVWLSYLKHKLVLPWSKRLVKNLSLM
                     ALIGLAIFVGALVLIIGISGFDITSLRLLGFGSGSNTSLLSRVDILLETGANQLNYAP
                     FLGNINVAYLTTGNAGQTLHSFFPYVMANLGLVGLLVVLTLFTNVLLQLYRETKQAKY
                     TGLYGYQLSMVALYSIFLFLYILLFANLSTGIEWPVLWFTLGFISKPFVFSERI"
     CDS             13812..15695
                     /EC_number="6.3.5.4"
                     /codon_start=1
                     /transl_table=11
                     /gene="orf12"
                     /product="asparagine synthetase"
                     /protein_id="ADF81000.1"
                     /translation="MCGFLGGFYKKAKDETLVQSSLDLIQHRGPDHSSFYKYVVDGGW
                     VYLGHTRLSIIDLTDSASQPFRSRCGGYVLIFNGEIYNYKEIKEELIDLGCSFETNSD
                     TEVLLYALMIWGVECLSRLIGMFSFVFYEQQQEKLLLVRDAFGIKPLFYSINDGEITF
                     GSEIRALLSLKNEKARPNLQRAYDYLVHGDYDSTQESFVDGVFHLSPAHYFTFDLKTK
                     TASKPERWWQPVISTNNNISFDDAVSQLRTLFLDSVRLHLRSDVPLGVALSGGIDSSA
                     VVSTIRYLEPSLPIKTFSYIASDSRISEEKWVDLLNEKIGAIAHKVVANQDEMREDLD
                     AMLLMQGEPFGGTSIYAQYRVFKLAKESGVKVTLDGQGADELLAGYSGYPGHRLLSII
                     ERQGWLAAHRYAKRWSKSPGRSYALAWQYLGRIILPDSLYELARKKMGRDFQPAWLNI
                     DYLRQRDVEFKEKRATLKQENKGVRVKEALANSLTGRGLSSLLRHGDRNSMAFSIESR
                     VPFLTLPLAEFLLSLPENYLVSDDGMTKHVFREAMRGIMPDSHLDRKDKIGFATPEST
                     WLLNMVDVMKEWISDAPELPFLDKSELLKEFQQVVEGSKSFDGRVWRWVNYLRWCTLM
                     GVE"
     CDS             15644..16822
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr2"
                     /product="glycosyltransferase"
                     /protein_id="ADF81001.1"
                     /translation="MALGQLPALVYIDGCRMKIANLVLNNFVNDSRVLKTSKSLSSLG
                     YDVCIVAMHDEGLKEKDLVGNVPVRRIKLTSRHWSKRKAVQLIKLFEFVFRFVFLCRK
                     VDVVHCNDLNGLFVGFCCKLTRPSLVLVYDSHEYSINPLPGQNFLTVKFNYFAEFFLI
                     RFAEQVINVSESIASEYERLYNIPKPHLVLNCPNYYEQPKRNLFRENLDIRKDQTIFL
                     YQGGLGKGRGIELLLEAFSNLDSDRNVLVCMGYGPLEALIQEKAQQQSTIFFHPAVTP
                     DVLLNYTSSADYGVSFIEDSCLSYRYCLPNKMFEYLMAGLPVLTSNLFEMKRLVETEG
                     VGIVAEENTVDGFKKAVEASLNQDYATIQKNVFAVRKKYCWEEQEENLKHIYEGLIDE
                     "
     CDS             16800..17735
                     /codon_start=1
                     /transl_table=11
                     /gene="orf14"
                     /product="D-glucuronyl C5-epimerase"
                     /protein_id="ADF81002.1"
                     /translation="MRGLLMNRKIYLDIRNYFFLKKEFGFESGENSYPLDLSFTYDDF
                     EFHYSPLDSRGIPCIEYESVGLQYNPTRIAAYALVNYNFFVKHNKHEYFDICILCANW
                     FLSIDSARYQYDFDWGDLKSPWISCMAQGEAASVLIRAYKLTGEDKYLLQAEKSLTPL
                     FLPITEGGVQSVLPDGSIFLEEYPSLKPTHVLNGFLYALIGLGEYIDVTGSKVHQDLF
                     DKLVNSLCQNISIWCYAGWSLYEDSVKAKGLNFCTPSYHNLQITQLKWLNKRVNNPDI
                     QHVIEVWEKGLNSFLMRVFALLGKVCFRLKNKAQR"
     gene            17732..18835
                     /gene="wbpH"
     CDS             17732..18835
                     /gene="wbpH"
                     /gene="wbpH"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="ADF81003.1"
                     /translation="MNKIAHLSSVHTRYDTRIFLKECTTLAKNGYSVSLVVADGKGDE
                     TKNNVSIYDVGASKGRLDRIRNAPGRVLTKALDLDADIYHLHDPELIPIGLKLKKHGK
                     VVIFDAHEDVPKQLLGKPYLNKPAKWLLSKTFAIYEHWACRQLDAVIAATPYIRDKFI
                     AIGVRSVDINNYPLLGELSTDEVDWSQKKAQVGYVGGIGQIRGISQVVQAMGMLHSDA
                     RLQLAGKFNEHVVEAAAHADKGWQHVDALGFVGREDVRDILSRCVGGLVTFLPSPNHI
                     DAQPNKMFEYMSAGVPVIGSNFPLWKQIIEGNQCGLCVDPLVPQAIAEAIDYLVTHPV
                     EAEQMGRNGQKAVQEQYNWGIEEQKLLSFYKSI"
     gene            18836..19915
                     /gene="wecB"
     CDS             18836..19915
                     /gene="wecB"
                     /EC_number="5.1.3.14"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="ADF81004.1"
                     /translation="MTKMQRIFTIIGARPQFIKASVVSRAIQQANGIEEIMLHTGQHF
                     DANMSDIFFNQLNIPRPHIQLDIHGGSHGDMTGRMLKEIEQALLTHKPDRVLVYGDTN
                     STLAGALAAAKLHIPVAHIEAGLRSFNMQMPEEINRILTDQVSDLLFCPTDTAVQNLN
                     NEGFVNKQVRVLQVGDVMQDAALLFAQKAVAPAGELPDEFILATLHRAENTDSPERLA
                     NIVNALNQLHQTLAPVVLPLHPRTRKLIAEQGLELNVHLTDPVGYFEMVWLLDKCQLV
                     LTDSGGVQKEAFFFGKACVTMRDQTEWVELIKAGANELVGADITRIIEASTRNVGRKV
                     QDTHNLYGGGKAAQQIVDVILKANI"
     CDS             19912..21138
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr3"
                     /product="glycosyltransferase"
                     /protein_id="ADF81005.1"
                     /translation="MSKTVWIVQQYASTPATGIGGRHYYLGRELVKLGYKVYLIASAS
                     HHLLREKPVLNQPFKIETLEEGFYFVWVNMPDYTEAHSKQRALNWFLFPWQIQKLARK
                     IADKPDAVLSSSPSLIAFLGAQRLAKKFKARLVFEVRDIWPLTLTEIGGYSPKHPFIR
                     LMQWVEDKAYRDSDAVVSNLKNSVEHMAGRGMARDKFSWVPNGFSLDEVNQKIPLNHT
                     AAAQLPKNKFIIGYTGTLGVANALQTLIEAAERLQEYTEIAFVLVGAGKEKAALQSLV
                     AEKQLRNIFFIDPIPKVEIQSILSEFDACYIGLTKDPLFRFGVSPNKLFDYLYSGKPI
                     VYGIESGEYKPIEDAKAGLQVPAQAPEQLADAVLSLYQMPAEERLAMGENGRKAALKQ
                     YEYGQLANQLIKVLFN"
     CDS             21548..22162
                     /codon_start=1
                     /transl_table=11
                     /gene="gtr4"
                     /product="UDP-N-acetylgalactosaminyltransferase"
                     /protein_id="ADF81006.1"
                     /translation="MKRVFDFLISLAVLIVLSPITVLVAWKIRSNLGSPVLFRQIRPG
                     LNGQPFEMIKFRTMKDAVDANGNPLPDSERMTPFGDKLRNSSLDELPELWNVLKGEMS
                     LVGPRPLLMQYLPLYSKEQARRHEVRPGVTGWAQINGRNAISWEEKFKLDVWYVDNHS
                     FWLDLRILLLTVKKVFVKEGISADGHVTIAPFTGKDQQGTGNER"
     CDS             22113..22814
                     /codon_start=1
                     /transl_table=11
                     /gene="orf5"
                     /product="lipid
                     carrier:UDP-N-acetylgalactosaminyltransferase"
                     /protein_id="ADF81007.1"
                     /translation="MPHLQGKINKEQVMNVKPVSKNSLGSCAILGASGHGKVIAEMAE
                     LNGYSDIHFYDDRWPSLGRVELWQVSGNSETLLKQARNYANVVVAIGNNATRLEKYNQ
                     LVASGASCLPLVHPSAIVSRYANVENGTVVMAGAVINPFSRIGQACIINTAATVDHDC
                     VIEDGVHLSPGVHLAGGVEVAQASWLGIGCQIKQLIKIGSNAVVAAGATVINDVLANQ
                     MVVGVPAKPICPKEL"
     gene            22817..23992
                     /gene="wecE"
     CDS             22817..23992
                     /gene="wecE"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase"
                     /protein_id="ADF81008.1"
                     /translation="MLNTPFSPWPSFTQEEADAVSNVLLSNKVNYWTGNECREFENEF
                     ATWAGCEYAIALGNGTLALDIALKALGVGVGDEVITTSRTFLASASAIVTAGANPVFA
                     DVDLNSQNITAESIAAVITEKTKAVIVVHLAGMPAEMDAIMALAAERGFYVIEDCAQA
                     HGARYKGRSVGTIGHIGAWSFCQDKIMTTGGEGGMVTTNDHALWSLMWSYKDHGKSYD
                     AVYNRQHPPGFRWLHESFGTNWRMTEIQGVLGRLQLRRMAEWTAKRQCNGKKLDQAVS
                     DLAVVRCVQVPDYIEHAEYKHYMFINPEHLKADWSRDRIIEKINMLGVPAYQGSCSEI
                     YLEKAFDNTSWRPAQRLTNAVILGETSLMFLVHPTLTTQEIEKSCDVIRSVLTEATR"
     gene            24275..25963
                     /gene="wbfY"
     CDS             24275..25963
                     /gene="wbfY"
                     /codon_start=1
                     /transl_table=11
                     /product="putative epimerase/dehydratase"
                     /protein_id="ADF81009.1"
                     /translation="MVSVGTLISTASVAIAAFYFNAPVPRSLPIIYGTFLCLLCGGSR
                     LIVRVLVSGLNGKGRKVVLIYGAGSAGRQLAIALRNSENYKVVGFIDQDKTLENTVIM
                     GLQVYDISRAAYLVDKYDVTQVLLAVPSASRARRKKILESLIDLSAEVLTVPDMKDIV
                     EGKASIDQLKDVAIEDLLGRDPVTPQQCLMESNILGKVVMVTGAGGSIGSELCRQIVR
                     QKPKALVLFELSEFGLYQIDRELKQLMEAEGLHVEIIPLLGSVQRINRLVVTMKSFKV
                     QTVYHAAAYKHVPLVEYNVVEGVRNNVFGTYYAAQAAIEAGVESFVLISTDKAVRPTN
                     VMGTTKRMAELGLQALAEQENRKTKGTRFCMVRFGNVLGSSGSVVPLFKRQIEAGGPI
                     TVTHPDIIRYFMTIPEAAQLVIQAGAMGKGGDVFVLDMGEPVRITDLAVNLIQLSGLE
                     VKDEQHPYGDIAIEFTGLRPGEKLYEELLIGDNVQKTAHERIMTANERYLPLAEFEQH
                     LNELDKACHAFNHERIRELLLEAPTDFNPTDGIGDLVWQRTQDNQTQLEKQFVH"
BASE COUNT     7435 a   4789 c   5940 g   7964 t
ORIGIN
        1 aaggcgtcat ggacccgaaa tcatcaccag ccatgatctg agctaggaag tcatctcgat
       61 ccatatagtc ggcgatctgt aggtcaacca gatttttgaa cttacgacca tttttcaaat
      121 gatcgacgac cagaatgtca gtgatgccac gctcattaag cgctttgata atgttgctgc
      181 caatcatgcc agcgccgcca gttacgataa tcattatgaa ttcctataga tgcgaacagt
      241 tgcacgcatt atagcctgtc atatctgtac tgtaatcaca aaatctaagc tccgcctttt
      301 gagggctcgc cctgtaaggg gttttggttt aaacttcgtg gcaaaacgca tgttgtataa
      361 cgctattagg agcgagacct aagggcggta gcgtgtcaaa aaaacttgta catctatact
      421 gcaggagcaa taagtgagtt cattagccaa tacccctccc gttcagccac cacaataccc
      481 acattatgcc tatcctgcta atgatgaaat tgatttaaaa gagctttttt cagccctatg
      541 gcaaggaaag tggctaatca ttatgaccac attgctgttt agtgtgaccg ctataggcta
      601 tgcattaaac gcccaagaat ggtggagtgc caaagcaacc attagtaaac cacaactaca
      661 aaatattact gcttatcaac aggctgtgaa acgttatcaa ccgctgtttg atgtgtacca
      721 agaagatggc accgttattg tcagtaatac attagatcgc ttgattgacc ctaagcttat
      781 ttttcaggaa tttattcaaa catttaatgc taacggcacc aaacgccgct ttatgcaaac
      841 caaccctact tttttaactt tgcaaaagca gatgttggat caaacaaatg ctccagagac
      901 catgcagaaa ctatatgaag cgtggtttga gcgcattcaa gcttctgcgg tagataaaaa
      961 caacgacaca tttaccttaa gctttcagtc tgtagataaa gccagcagct taaccttact
     1021 taatgagtat attcagtttg ttaatcaaac cctaagtcag caccttaatg atgattttgt
     1081 tagtacctta gcttccaaat atggcgaact ggcacaacaa gagaagagcc tacttcaaca
     1141 agcacaattg cgtttacaag ttgagttaga gcgtacccaa tatgctttaa acattgctga
     1201 tgcggctgat attaagctgc cagtacaaaa tttaggtgaa caagagcttt tcgcgattaa
     1261 tattggtagc cgcgccttaa aagccaaagt ggacgcttta aaatcgatta aagatttgag
     1321 tgtgtttgag ccaagactgg cgattttaca aagtaagctg agccagttcg atttagaaac
     1381 gttaagtgcg gagactaagt ggtcggtaaa cggcttttac tatttagacc aaccggaaca
     1441 accattaact agagataagc ctaagcgcgc tttaattgtg gtgtttggtg gtttacttgg
     1501 cggaatgctg ggggtggctg tggtattagt gagatttacg tttagaagag atgactaaaa
     1561 attcgagtca tcaatatcta ttaggaatgg ttgaagtaaa acctagattt aacaatagat
     1621 ggcgaagatg tggctgtctc aaaatggacc aaaattttct cattggtgga agagtgctta
     1681 gataaaaagt agcaaataag agtgattaag atgataaaaa atagaaaaat tcgaatagca
     1741 gtcgttggtt gtgggcgtat ttctaaaaat cattttggct caattgagca gcttgattca
     1801 gaatatgagc tggtcgcggt gtgcgataat aaccctgaag ttttagagct acattcaaat
     1861 aaatacggcg ttccgggtta tcactcgata gatgatctgc tcgcttcaca aacacttgat
     1921 atcgtcacct tgtgtacccc gagtggcata cacgcaccac aaactattaa agctgcgaaa
     1981 gccggtatac atgtgattac cgaaaaaccg atggcgacca agtgggaaga tggactagca
     2041 atggttaaag cgtgtgatga agctggggtg cgtttatttg tggttaaaca aaaccgccgt
     2101 aattcaacat tgcaattact taagcgtgca gtgacggaaa agcgttttgg taaaatccat
     2161 atggtgcatt taaatgtgtt ttggacccga cctcaagagt attacgaccg cgctgcttgg
     2221 tctggcactt ggcacatgga tggtggtgcc tttatgaatc aggcgactca ttatgttgat
     2281 ctcctacatt ggctagtggg gcctattgaa accatccatg ccatgacctc cactcatcgt
     2341 gatattgaag tcgaagatac tggagtggtg aacatcaaat ggcgtaatgg cgcgttaggt
     2401 tcaatggcgg taactatgtg tacttacccc aataatttag agggttcaat tactattttg
     2461 ggtgaaaaag ggacggtgcg tgttggtggc gttgcggtta atcaaattca agaatggaac
     2521 tttgctgaat caaaagatta cgatcagcaa attgaacaag ccaactacca aactacttca
     2581 gtctatggat ttggtcatcc accttacttt aaaaacgttg cggatgtatt acgtggcgag
     2641 gcagagccag aaaccgacgg ccgtgaaggt ttaaaatcac ttgagctatt gatcagcatt
     2701 tatcgctcag ctcgcgatca taaagaaatt ggtttgccat tgaatctgta attacgagta
     2761 aagaaaaatg aagttagaaa atttaaatat tggcattatt ggtttaggtt atgttggttt
     2821 gccgcttgct gtggagtttg gtaaaaaatt taacacggta ggttttgata ttaatcagaa
     2881 aagggtcgct gaattacgtt caggtgttga tttgacctta gaatgttccg aagaggaact
     2941 gcgtagtgct ccattgctga gttacactca ccaattggaa gagattaaag attgtaattt
     3001 ttatattgtt accgtcccaa cccctattac cgatgaaaaa acgcctgatc tcaaccctct
     3061 aaaaaaagcc tctgaagcgc ttgcgaaagt tatctctcac ggcgatgttg tcgttttcga
     3121 atcaacggtc tatcccggtg caacagagga agtgtgcctc cctattatcg agaaaaattc
     3181 agggttagtg tttaaccgtg atttctttgc tggttatagc ccagagcgta tcaatccagg
     3241 agataaagtg aatcgtttaa ctacgatcat gaaaataact tctggctcta cgcctgaagt
     3301 ggctgatttt gttgatcaag tatacgcttc gatagtcact gctggtaccc ataaagcgcc
     3361 atcaatcaag gtggcagaag ccgctaaagt tattgaaaat acccagcgtg atctaaatat
     3421 tgctgtaatc aatgagtttg ccaaaatttt taatcgacta ggtattgata ctgaagctgt
     3481 tttaaaagca gctggcacaa agtggaactt tttgcatttc aagccggggt tagttggagg
     3541 tcactgcatc agtgtggatc cttactacct cacccataaa gcacaagaag ttggctatcg
     3601 accagaggtg attttagctg gtcgtcgtat taatgatggt atgggtgaat acgtcgccac
     3661 acaattagtt aaagctttgt cacgtaaaaa aattcatatt gatgaagcaa aagtgctgat
     3721 catgggcttt acctttaaag gtgattgtcc tgatgttcgt aataccaaaa ttattgatat
     3781 tgttaacgaa ttgcaagatt tcaacatgtc agttgatgta tacgatagct gggcctcgaa
     3841 agaggaagtg aagcatgagt acggtattga gttgattgat gagctgcgcg atggttacta
     3901 cgatgcaatc gtactggccg tggatcatag tcaaaccaaa cagatgggtg ttgaaaagtt
     3961 acgtcgttta ggtaaaaaag agcatgtact ttatgatgtg aagcatgtat taaccgccga
     4021 tgaagcagac atccgccttt gattaatagc caaactactt ggagttgcag gtaggcggca
     4081 agtgagtgaa tgaatcccca tgagcataga taaactatgt gataggggtg aaccaacgta
     4141 gccaacaccg ctgcagcttc aagtagtaag ggtgtagcct tcacaagggt agtgttcagc
     4201 ttcccttctc aatcgataga acatttttca tgaaatattt taaacacgaa accgccatta
     4261 ttgatgatgg tgcacaaata ggtgatggca gccgagtgtg gcactgggca cacgtttgtg
     4321 ccggtgccca tattggccaa ggagtgtcac tgggtcaaaa cgtatttgtg ggcaacaaag
     4381 ttacaattgg cgatcattgt aagattcaaa ataacgtctc agtgtatgac aacgtgcatt
     4441 tagaggaggg agtattttgt gggccaagca tggtatttac caatgtttat aatccgcggt
     4501 caatgattga acgaaaagat caatatcgcg ataccttagt cagaaaaggg gctacgcttg
     4561 gtgctaattg tacgattgtc tgtggtgtga ctattggtga gtttgccttt atcggcgcgg
     4621 gggcagttgt gaacaaagat gttcctgctt atgcaatgat ggtgggtgta ccggctaaac
     4681 aaaaaggttg gatgagtgaa tttggtgagc agctagactt gccattgagc ggagacgctg
     4741 aagtgatttg tcctcataca ggtgctgttt ataccctcag tggtgacact gttattaaaa
     4801 acatcggtgc taataaataa ttcttcaatg taaatatatt tacaagttgc tgaggattca
     4861 cttggctatc tggctaggag ctaaaaatgc agtttattga tttgggtgcg cagcaggcgc
     4921 gaattaaaga aaaaattgat gtcggaattc agaaagtact cgcccatggt cagtatattt
     4981 tgggccccga ggtggctgaa ctagagcaaa aattaattgc atatactgga gctaagcact
     5041 gtatctcggt tgctaatggt acggatgcat tgcaaatcgc ccaaatggca ttgggtgttg
     5101 gcccaggtga tgaagtgata acacctggat ttacttatat cgccaccgca gaaaccgtcg
     5161 cccttttagg agctaaaccg gtttatgttg atgtctgccc gaaaacttac aatttagacc
     5221 cgactaaact agaagcggct attacgccaa ggaccaaagc aattattcca gtaagtttgt
     5281 atggtcaatg tgctgacttt gatgcaatta atacgattgc cgccaagtat ggcataccag
     5341 tgattgaaga ctctgcgcaa agttttgggg ccagttacaa aggcaaaaaa tcgtgtaact
     5401 taagcaccat tgcctgtacc agttttttcc caactaagcc attaggttgc tatggtgatg
     5461 gcggtgctat tttcactaat gatgatgaat tggcccttgt catgcgccaa attgctcgtc
     5521 acggacagga tcgtcgctac catcatattc gtgtaggtat aaacagccgt ttagatacct
     5581 tacaagctgc gattttatta ccaaaacttg aggttttgca tgaagaaatc gagctaagaa
     5641 atcaggtagc caatacctat actcgtttat taaataatgc tggtattctc tcaaccccat
     5701 ttgtggaagc tcataatatt tcggcttggg cacaatatac catccgagtt aagtatagag
     5761 ctgaaattca gcacaagctg caagaagctg gcattccaac tgccgtacat tatcccattc
     5821 ccttgaataa acaaccagca gttgctgata gaagtattca attgccgata ggcgatgaaa
     5881 ttgcagaaga agtgatgagt ttaccaatgc atccttattt gactgagcaa gatattcaac
     5941 gtgtggtaga gagtttggca cagtgagttc tgttcctcat cgtaaggata ttcaaggatt
     6001 aagagccata gcagtacttg ctgttatggt ttttcactta aacccgacat ggcttcctgg
     6061 aggctttgtt ggtgtcgatg ttttcctcgt gatttctggc tttttaatta ctagcatttt
     6121 gctgcataaa aaatccagtg ctggctattc tcttactgaa actctgaaat atttctatgt
     6181 gagtcgcttt aagaggattg ttccagcata ctttttgatg ctcgttatga aatagctatt
     6241 atgttgccaa aagatgatga ggatgcccgt cttcttttgc aactttcaat gctagttgct
     6301 ctgttttttt cttttctgat tagtatacct atatcgattt ggaatgcgca aattgctcgt
     6361 tttctaggta atgaggatat tgctgtttgg ttgtacttag tccctgtatc tgtgttgttc
     6421 acaggtattt atcaagcact aacttattgg aataataggc agaaaaaatt cataaacaca
     6481 gcagtgtcgc gtgtgaatca aagcttattt caaggtttct cccaaacgtc acttggtttt
     6541 ttacaggtat caggtggtct tatttgtggg cagttcgtag gaatagtatc tggtttaata
     6601 taccttttaa agaaagatag aaactataag tcgctaataa gaaaatcaaa aataaattcg
     6661 atacaaaaac aaggtataaa gtatcataag ttcccgactt atggagtttg gggggctctg
     6721 tgcgatgcag gagctgtaca aatgccggtt atactgttga cgaagttcta ttcaaattcc
     6781 gtgacgggaa tgtttagtct gacttttcgt gttttgaata tgccgacatc gattatttca
     6841 tctgctattg cacaggttct ctttcaaaag gtagttgaaa taagtcaaac agagccagag
     6901 aaacttaatc tttatataat aaaaatgttt ttgttacttt ttattatata cctccccgca
     6961 gtgcctgttt tattcatatg gggtgaaagt ttgttttcaa ttatttttgg tagtgaatgg
     7021 tcacaagctg gggtttatgc aggttattta gtcatagctg ttgcagtacg tttcgctgtc
     7081 agcccattaa gtgcagttct tggtttagaa caaaacataa agatgggggt tttatggcaa
     7141 gttctctatc tatgtacgat tagtgtaaca ttgtatttct cctcttctct ttcaattgaa
     7201 gagtttctga ttgcttttgt tgtgcatgaa gttgttttat atcttattta tttgttcctt
     7261 attcttaaag gaactaaaaa aatagctaaa tgctaaaaaa ttttaaggtt taatatgtgt
     7321 ggaattgctg gttatatttt tagtggcgta ttagataaat cgaatcttaa gaaaatgact
     7381 gattcaataa ttcatcgagg tcctgatggt gaggggcatt attatggaga tggttttttc
     7441 tttggacatc gtagattagc tattgttgat ttaaccgagc atggtaaaca gccaatgctt
     7501 tatcaagata gatatataat aacttttaat ggcgaaattt ataattatat agaaataaaa
     7561 aaagagctta ttgatgtagg atatcgattc aataatgata ccgatacgga agtcattatg
     7621 gcggcatatg attactgggg agtaaattgt cttgaccgtt ttaatggtat gtgggcattc
     7681 gttctatatg ataagaaaga ggatgttttt tttatatcac gtgaccgatt tgggaaaaaa
     7741 ccgctttatt acagcttaga taacaataaa tttgtatttt gtagtgaagt taaaggtctc
     7801 tatgctagtg gattggtaga aaaagcaccc aacaaaagct acctgaaaaa ctacgtggaa
     7861 aacgggccta atgagtacga tgcagaaacg gctttcgcta acgtttatcg ttttcctttt
     7921 gcacactact ttcttggtag caaagaacaa ctgctcaatc aaccgaagtt tactcggtac
     7981 tgggaattaa ccactaatac tagcaaagaa cgcttctgcc ccagtaaagc caaagaatac
     8041 gccaaacaat attacgacct actagcagat gcggtaagac tacgcttaag agccgacgta
     8101 aaagtgggtt ctgcactttc aggcggttta gacagtagct cgattgttta cctagtcaac
     8161 gaacagttaa gagctcaagg taaagctgat ctacaggaaa ccttttcttc tgtttacaag
     8221 tctgatggta cccagaattg tgatgaaagc gtatatatag accttctagc aaaggcgctg
     8281 aatgttaatt caaatcaaat agagcctcag gaaggtgata ttcctgttga gcatcaaaaa
     8341 atgatttggg ccatggaaaa tccaccagaa agtacctgta tgtctggttg gcacaccttt
     8401 attaaagtga aagaatcagg tgtaaaggta actttagatg gccaaggtgc tgatgagcag
     8461 ttagctgggt atctacctta cattgctagt tatttaacat cgatttcatt gattgactta
     8521 tataaagagt tcttttattt cttaaaaata ccaggtgcga aaaaaacgtt actgtttagt
     8581 tttttaatgg caaattttaa gttcatcttc ggtatgaaag cttatcaagc gctattcaaa
     8641 aaaataaaag ggcgacaacc acctactgaa ttaaatttag aattaaaatc tgctatcgaa
     8701 aagggattaa ttaaccttat tcattactct gatcgtgttt caatgggaca cagtatagaa
     8761 tccagaatgc cctttatgga ctatcgatta gtcgagtttt tagctcaagt tcctgcatgt
     8821 tataaaatgc ataatggttg gactaaatac ttggctcgcc tagcattcga caaaaaacta
     8881 cctgatgaaa ttacctggcg aaaagacaaa atgggttggc caattccgga agaacattgg
     8941 ttcagaggaa acttgaggtt gtgggcttca gatacattaa tgaattcaaa agttttaaaa
     9001 gaaatatctc cagaattaga tgcagagact gagtttaaaa gcaatataaa gaagagcata
     9061 agaaagctga atattgcaac tattaataaa ttgaattttt ggtgattcat atatgcgaat
     9121 tctgataatt acaagtgggt tgacgcgtat tgtctcacct gtattagata gtggccatga
     9181 gattttaggt atcgttgaat ctatgccacg aggttggagt gaaaagcaag aaaaaccttt
     9241 tctttttcag tttgcccaaa aaatacacag gattttcttg gggagaaaga aaacgttgaa
     9301 gcaattctgt gagattagaa atataagata taactatata tcaaaaggaa gagatgcaga
     9361 ggtaactaat tgggttaagg aactcaaccc cgacctgatt gtagttttta gcatgtctca
     9421 actccttaaa aaagatttaa tagatattcc caaatatggg gttataaacc tacatccatc
     9481 aatgttgcca gagtatcgtg ggcctaatcc agatttttgg cagtactata atatggaaat
     9541 gaacccaggt gtaacggtcc attatattga tgaaggtgaa gatactggag atatcatctt
     9601 tcaggaacgt gtgcatatcc ctttaggaat caagtcacct gaaaggctgg ataagctaat
     9661 tggtggtgtt ggctcttctc tgcttgtaaa ggcaatccaa gctataaaat cgggttcggc
     9721 accacgaatt ccccagccaa gccatagttc aactcttcga gccagaaact taaaatccga
     9781 agaacacaaa gaaattatag attggcaaaa ttggccgata gaacgaattt ggcatgtgct
     9841 acgtggtaca gagctttggc ttaatgctta tgatcaaccc aaaggcattt ttaaaggcca
     9901 gcgatgggtc gtcggagagt acgagagaaa ggacaatatt gatctgccgg gtgcgatagt
     9961 gcgttataaa ggaagaaaag ctctggcgac tccagatggt tatattttta ttgatataaa
    10021 cttcagctta aaaaaagctt tacttttcgt acttaatttt aaattttgag tgaatcaatg
    10081 atcaataaag aaaaatatcg tcaattgtgt gaagaagaac ctactattcc aattttcagt
    10141 caagcttggt ggttagacgc cgttgctaga gataactggg atgtgtgtat tgtcgagaaa
    10201 ggtgataaaa tacaggcaac aatgccttat ataatacaga agaaatttgg gctaacccta
    10261 ttgacccaac ctaaactaac ccaaacactc ggtccttggc ttagaccttc aacggcaaaa
    10321 tacagtaaac agctttcaca gcaaaaagat ttgatggaag cactgattga tcaactacca
    10381 aaatatcact acttcagcca aaactggcat tattccaata ccaactggtt acctttttac
    10441 tggaaaggat ttgagcaaat aacgcgttat acttatctga ttgatgactt atctaatatc
    10501 gatgatgttt gggattcctc gcttgcaaat atcagaacag atattcgcaa ggctgagaat
    10561 aagtttaatc ttgttgtaaa ggaaaatttg ccattcagtg attttttatt acttaatcgt
    10621 caaaccttct tacgacaagg aatgcaatta ccttattccg aaagctttgt aaaccagttg
    10681 gtatttacag caaaagatcg taatcaatgt cgctggttta ttgctcaaga taacgaaggc
    10741 agaaatcatg caggtgtttt gctggtttgg gatagtgaat cggcgtatta cttaatgggt
    10801 ggtggtgatc ctgatctaag aaatagtggt gcaacgagcc tttgtatgtg ggaagcaatt
    10861 aaatttgcat caactgttac aaagcgattt gactttgaag gttctatgat tgaaccggtt
    10921 gagcgtttct tcagagcttt tggcgcaaaa caaaccccat actttgcact cactcatcga
    10981 ccttcgcgtt ggttaaatac ggcaattcat tttaaaaaag ccctaaaagg tcaagcttag
    11041 ttttgaacaa atgcttactc actctataaa atcttttaac aacattgcta cggcaggtaa
    11101 actccaagaa aggtaataca tgattcattt ttctgatggt gcaatacgtt ggctcgagac
    11161 cattttattt gaacgttttg gccatcgttt tatacttgct gaacaaccta atacgctaca
    11221 attttattta aatgatagtc agggctctat agcgtttcct agcctgcaag gcatatttca
    11281 tcagtcgcgt tcagatttcc cgtgtcagca gtggcaagct tccagcgaag actttatagc
    11341 gccaatcgaa gactacatac cagccccttt cttaaacgca ctaccaagcc cgcttattga
    11401 gtttactgag caaggagcaa ttgtacacta cgatattctc ggtttaacct actgggtgct
    11461 aacgaggtta gaagaagttg gacgtaagga tttagataat catcaacgct ttccagcggt
    11521 ttcttctcac gcttatcagc atggttatct tgagcgccca attgttgatg aatggctgat
    11581 gattctaggg caggttattc agcgtgtttg gcctgatatt gagttaaagc aacatgagtt
    11641 cagtattaag gtctcgcacg atgtagatag cccgagcatg tatggtttta aaccttggcc
    11701 gaccatcggc cggatgatgg cggggcacct gctgaaacgg cgcgatctca aggctttttt
    11761 tacggcaccc tatgttaaac ttgcgacaca cagccagcta cacccaaccg atccttacaa
    11821 cacctttgag tggttgatgg atatatctga agctaacaac atcaaaagtg cattttattt
    11881 tatctgtggt ggtaatcatt ctcatgacgc cgattatgaa cctgagcatc ctgcgatccg
    11941 taatttgatg cgccgaatcc acgaacgcgg tcatgaaata gggttgcatc ctagttacgg
    12001 tactttccag cagcctgagt tgattaagca agaagcagaa cggcttaaac gcatttgtgc
    12061 ggaagagagt attgagcaac aactatgggg tggacgaatg cactacctgc gctgggaaca
    12121 acccactacc atgcgagctt gggcgggggc aggtatgact tatgattcta cacttggtta
    12181 tgccgatagg ccgggttttc gctgcggcac ctgttatgaa tatcctgctt ttgatcccgt
    12241 ggctcatgag caattgaacc ttcgaatcag gccgctggcg gtgatggagt gtacggtgat
    12301 tgatgctgtt tacttagggt taggtgtaac tgaagccgca gaagaaaaaa ttcagcaatt
    12361 gaaaatgcgc tgtcagcagg taagcggtac ttttggttta ctatggcata attcatactt
    12421 taaaaattct aatttacgga atatttataa aaatgttcta ggaagtcagt tgtgagattt
    12481 ataccatata ataaagtcat tgtattaaag ataataatta ttcttcaact caccacatta
    12541 ctaatttatc tcaatgcaaa cattgttaat gttggtgaga tgggagttgc cttacactta
    12601 cttgtagagt ttgtgggctt gacaagtttg ttatttgcga tgttttgggt aaaaaaaaag
    12661 ctctacttcc atatccactt ttttttcttc cttttactaa tatgttggat agcttttcga
    12721 atagtttttg atttaaatga tcttgaatat ttaaaacaac taacagtggc taccactggt
    12781 ggtgttttat tgttttatat tataggtgca tcactaggtt taacgaggca tagtctggct
    12841 agccttagga gtgatataaa gatagaaaaa tatattattt tactttttta ttttctatct
    12901 atctggatgc tctacaattt ctctcagcgc ctacatgatt cgcttttcta cttaaaagat
    12961 attgatggta gctatcaaag gtctggaaat ttcttatcaa tctcatttat tattatttca
    13021 ttcgcttacc ttaatctagt attaaagaat gttgctcaag gtgctactat tttagctagg
    13081 tttttctggt tgttcgtata taccttatca accttgatgg cattagttgg atcacagctt
    13141 tttggctcta atagcgcaac cgctgttatt ttaggtgttt atcttattac gctggttatg
    13201 tctcttgtaa ctgctaaaaa aacagtctgg ttgagctatc tcaagcataa actagtctta
    13261 ccttggtcga agcgcctagt gaaaaatctt agcctgatgg ctctaattgg cttagctatt
    13321 tttgtagggg cactggtgct gattataggt atatcaggtt ttgatattac tagtttgcgg
    13381 ttactaggct ttggttctgg ttctaatact tctttactaa gcagagtgga tattttatta
    13441 gaaactggag ctaatcaact caactatgct cccttcttag gtaacataaa tgttgcttat
    13501 cttaccactg gtaatgcagg ccaaactctg catagttttt tcccttatgt gatggctaac
    13561 ttggggctgg taggattact agtcgtgctg actcttttta cgaatgtact actacagctt
    13621 tatcgtgaga ctaagcaagc taagtatact gggctttatg gttatcagct aagtatggtt
    13681 gcactttatt ccatttttct gtttctctat attctattat ttgcgaactt gtccactggt
    13741 atcgagtggc ctgttctttg gtttacgctt ggttttatat ccaagccttt tgtttttagt
    13801 gagcgtattt aatgtgcggt tttctaggcg gtttctataa aaaagccaaa gatgaaactt
    13861 tggttcaaag ttcgttagac ttaattcagc accgtgggcc tgatcatagt tctttttata
    13921 agtatgtggt tgatggggga tgggtatatt tgggccatac tcgactttcc atcattgatt
    13981 taacagattc tgcctctcag ccatttcgtt cacgatgcgg tggatatgtg ctgatattta
    14041 atggtgaaat atataactat aaggagatta aggaggagtt aattgattta ggatgctcct
    14101 ttgaaactaa ctctgataca gaagtattat tatatgcatt gatgatatgg ggtgttgaat
    14161 gcctgtccag attgattgga atgttttcat tcgtttttta cgaacagcaa caagaaaagt
    14221 tgctacttgt tcgagatgcc tttggaatta aaccgttatt ctattctatt aatgatggtg
    14281 aaattacatt tggttctgag attagagcac tgcttagttt aaaaaatgaa aaggcgagac
    14341 ctaatttaca gcgtgcatat gactacttag tgcatggcga ctatgactcc actcaagaat
    14401 cgtttgtcga tggtgtgttt cacttatctc ctgcacacta ctttaccttt gatctaaaga
    14461 caaaaactgc ttctaaacct gaacgctggt ggcagcctgt aattagtaca aataacaata
    14521 ttagttttga tgatgcagtt agtcagctaa gaacactgtt tttggacagt gttaggctcc
    14581 atcttcgaag tgatgtaccg ctgggggttg cgttatctgg gggaattgat tcttctgcgg
    14641 tggtttcaac tattcgctac cttgaaccaa gccttcctat taaaactttt agctatatag
    14701 cgagcgattc tcgcatctca gaagaaaagt gggttgatct tctgaatgaa aaaattggtg
    14761 ctatagctca taaagttgtc gctaatcaag atgaaatgcg agaagacttg gatgctatgc
    14821 tccttatgca gggcgagcct ttcggtggta caagtattta tgctcaatat cgtgttttca
    14881 agcttgccaa agaatcaggc gtaaaggtga ctctggatgg ccagggggcc gatgagctgt
    14941 tggcaggcta ttctggttat cctggtcacc gtttgctcag tattattgag aggcaaggat
    15001 ggttagctgc gcatcgctat gctaaacgct ggtcaaaatc gccaggtcga agttatgctt
    15061 tggcttggca gtatctgggt cgtataatat tacctgattc tctgtatgag cttgcgcgta
    15121 agaaaatggg acgtgatttt cagccagcat ggttgaatat tgactactta agacaaaggg
    15181 atgttgagtt caaggaaaaa cgtgccacat tgaaacagga aaacaaaggt gtaagagtta
    15241 aggaggcttt agctaattca cttacaggtc gtggattatc ttctttgtta cggcatggtg
    15301 accgtaattc aatggcattt tcaatagaaa gccgtgtgcc atttcttact ttgcctttag
    15361 ctgaattttt attgtctttg cctgagaatt acttggtttc agatgatgga atgactaaac
    15421 atgtttttcg tgaagctatg cgcggtatta tgcccgatag tcacttagat agaaaagaca
    15481 agattggatt tgctacacca gaatcaactt ggttattgaa tatggttgat gtaatgaaag
    15541 aatggatttc cgatgcgccg gaattaccat ttttagataa atctgaactt ttaaaagaat
    15601 ttcagcaagt tgttgaaggt agtaaatcat ttgatggtcg agtgtggcgt tgggtcaact
    15661 acctgcgttg gtgtacattg atgggtgtag aatgaaaatt gctaatcttg tgttaaataa
    15721 ttttgttaat gatagtaggg tgttaaagac ctcgaaatct ttaagttctc ttggctatga
    15781 tgtatgcata gtggcaatgc atgatgaggg tttaaaagag aaggacttgg ttggtaatgt
    15841 tcctgttcga cgaataaaat taaccagtag acattggtca aagcgcaaag ctgttcaact
    15901 aattaagcta tttgaatttg tttttagatt tgtttttctc tgcagaaaag tagatgtagt
    15961 tcattgcaat gaccttaatg gtctgtttgt cggtttttgc tgcaagctga ctcgaccaag
    16021 tttagtttta gtttatgatt ctcatgagta ttctattaat cctttgcctg gtcaaaattt
    16081 ccttacggta aaatttaatt attttgctga gttttttcta attcgttttg ctgaacaggt
    16141 gataaatgta agcgaatcta ttgccagtga gtatgagcgc ctctacaaca ttccaaagcc
    16201 ccatcttgta ctcaattgtc ccaactacta tgagcaaccc aagcgtaatt tattccgtga
    16261 aaatttagat attcgcaagg atcaaactat ctttctctac caaggtggac ttggtaaagg
    16321 tcgaggcata gaactattgc tcgaagcttt ttccaatctt gattccgata ggaatgtatt
    16381 ggtttgcatg ggttatgggc ctcttgaagc tttgattcaa gaaaaggcgc agcaacaaag
    16441 cacaattttt tttcatccag cggttacccc agatgtattg ttgaactata ccagctctgc
    16501 tgattatggt gtttcattta ttgaagattc ctgtctgagt tacaggtact gtttgcctaa
    16561 caaaatgttt gagtacctta tggctggttt gccggtgctt acttcaaatc tgtttgaaat
    16621 gaaacgattg gttgaaacag aaggtgtcgg cattgttgct gaggaaaata ctgttgatgg
    16681 ttttaagaag gcggtagaag cttcgctgaa ccaagactat gctaccatcc agaaaaatgt
    16741 atttgcagtc cgcaaaaaat actgctggga agaacaagaa gaaaatttaa agcatattta
    16801 tgaggggctt attgatgaat agaaagattt accttgatat caggaactac ttttttttaa
    16861 aaaaagagtt tggttttgag agcggtgaaa attcctaccc tttagattta tcgttcactt
    16921 atgatgattt tgaattccac tatagcccat tagattctcg tggaattcca tgtattgagt
    16981 atgagtcagt aggtttgcag tataatccaa cacgcatagc tgcatatgcc ctagtaaatt
    17041 ataatttttt tgtaaagcac aacaagcatg aatattttga tatatgtatt ctttgtgcta
    17101 actggttttt aagtatagac tctgcacgct accagtacga ctttgattgg ggtgatctaa
    17161 agtcaccctg gatatcctgc atggctcaag gtgaagcagc aagtgttctt atcagagctt
    17221 acaaattgac gggtgaggac aagtacttac tccaggcaga aaaatcactt acaccattgt
    17281 ttttgcctat cactgagggt ggcgtacagt ctgtactacc tgatggttct attttccttg
    17341 aggagtatcc ttcacttaaa ccaactcatg ttcttaatgg ctttctttat gcattgatag
    17401 gcctcggtga atatattgat gttacgggca gtaaagttca tcaagattta tttgacaagc
    17461 ttgtaaactc actttgtcaa aatatcagta tttggtgtta tgcaggttgg tctctttatg
    17521 aggatagtgt taaggctaag ggcttaaatt tttgcacacc ctcttatcat aatcttcaaa
    17581 ttacacaact caagtggctc aataagcgag tcaacaaccc agatattcaa catgttatag
    17641 aagtctggga aaaggggctc aacagttttc ttatgcgtgt ttttgcgctt ttaggaaagg
    17701 tgtgttttcg ccttaagaat aaggcacaga gatgaataaa attgctcact tgtcttcagt
    17761 acacactcgc tatgacaccc gtattttcct aaaggaatgt acaacccttg ctaaaaatgg
    17821 gtactcggta tcactggtcg tagcagacgg taagggtgat gaaactaaaa acaatgtgtc
    17881 tatctacgat gtaggcgcat ctaaagggcg tttggatcgc attcgtaatg cacctggtcg
    17941 tgtgttgact aaagctttgg acttggatgc agatatctac catctgcatg atcctgaatt
    18001 aatccccatt ggtttgaaac tcaaaaagca cggcaaggtg gtgatttttg atgcccatga
    18061 agatgtaccc aagcagttgt tgggtaaacc ctatctaaat aagcctgcca agtggttgct
    18121 gtctaaaacc tttgccattt atgagcattg ggcctgtcgt cagttggatg ccgttattgc
    18181 agcgacccct tacattcgtg ataagtttat tgcgataggg gtgcgttctg tggatatcaa
    18241 caactatcca ctattaggcg agctctcaac tgatgaggtc gattggtcac agaaaaaagc
    18301 acaggttggg tatgttggtg gtattggaca gattcgaggt atatctcaag ttgttcaagc
    18361 tatgggtatg ttgcactcag atgcgcgttt acagctagca ggtaaattta atgagcatgt
    18421 tgttgaagct gccgcccatg ctgataaagg atggcaacat gtagatgcac taggctttgt
    18481 tgggagggaa gatgttcgtg atatactgtc tcgttgtgtc ggtggtttgg ttactttttt
    18541 accttcacct aaccacatcg atgcgcaacc caacaaaatg tttgaataca tgagtgctgg
    18601 tgttcctgtc atcggttcta attttcccct ttggaaacaa attattgagg gtaatcagtg
    18661 tggcttgtgt gttgatccac tggttcctca agcgatagca gaagcgattg actacctggt
    18721 tactcatcct gttgaggctg aacaaatggg acgtaatggc cagaaagcgg tgcaggaaca
    18781 gtacaactgg ggtatcgaag agcaaaagct acttagtttc tataaatcca tataagtgac
    18841 aaagatgcaa agaattttta ccatcatagg cgcacgtcca cagtttatta aagctagcgt
    18901 tgtatcacgc gctattcagc aagccaacgg tattgaagag attatgctgc atactggcca
    18961 gcattttgat gccaatatgt cggatatttt tttcaaccaa ctgaatattc cacggccgca
    19021 tattcagtta gatattcacg gtggtagcca cggtgacatg accgggcgta tgctgaaaga
    19081 aattgaacag gccttgctaa cccataaacc agatcgggtc ttggtgtatg gagataccaa
    19141 ctcaacactt gctggcgcgc ttgcggcagc aaaactgcat atacctgttg ctcacattga
    19201 agcaggcttg cgcagcttta atatgcaaat gccggaagag attaatcgta tcctcaccga
    19261 tcaagtgagt gatttactct tttgcccaac ggatacggca gtgcaaaatc tgaataacga
    19321 aggctttgta aacaagcagg tacgggtatt gcaagttggc gacgtaatgc aggatgcggc
    19381 gctcttattt gcccaaaaag cggttgcacc agcaggtgag ctgccagatg agtttatttt
    19441 ggctacatta catcgtgctg aaaacacaga tagccccgag cgcttggcga atattgtgaa
    19501 tgcactgaat caacttcatc agactttagc tcctgttgta ctccctttgc acccacggac
    19561 gcgcaaactg atcgccgaac aaggtcttga gttgaacgtt catttgactg atcccgtcgg
    19621 ttattttgag atggtctggc tactagataa gtgtcaattg gtactgacag atagcggcgg
    19681 tgtgcagaaa gaagcgtttt tctttggtaa ggcttgtgtc acgatgcgtg accaaaccga
    19741 atgggtagag ctgataaaag cgggagctaa tgagttagtt ggtgctgaca ttacaaggat
    19801 tattgaagcc tctactcgta atgtcggacg taaagtccaa gatacacata atctgtatgg
    19861 tggcgggaaa gctgcgcagc agattgtgga tgttatcctg aaggctaata tatgagcaaa
    19921 acagtttgga ttgtacaaca gtacgcgtct accccggcaa cggggattgg agggcgccat
    19981 tactacttag ggcgtgaact agtaaagctg gggtataagg tatatttgat tgcttctgct
    20041 tcacaccatc tgttacgtga aaagccagtt ttaaatcagc catttaaaat agaaacgctg
    20101 gaagaaggtt tctattttgt gtgggttaat atgcctgatt atacagaagc acacagcaag
    20161 caacgtgctt tgaattggtt tttattccct tggcagattc aaaaattggc acgaaaaatt
    20221 gctgataagc cggatgctgt tttatcttct tctccctcac ttattgcttt tttaggcgct
    20281 caacgactgg ctaaaaaatt caaagcccgt ttggtttttg aggtacgtga tatctggccg
    20341 ttgaccttga ctgaaattgg tggttattca cctaagcatc cttttattcg tttgatgcag
    20401 tgggtggaag ataaagccta tcgtgactct gatgcggttg tatctaatct taaaaattct
    20461 gttgaacata tggctggccg tggtatggcg cgtgataaat tcagttgggt gcctaatggg
    20521 ttctctttag atgaagtgaa tcaaaaaatc ccactcaatc atactgctgc cgctcagctt
    20581 ccaaaaaata aatttatcat tggctataca ggtacgctgg gcgtggctaa cgcgttgcaa
    20641 acgctaattg aagctgctga gcggttgcag gaatatactg agattgcctt cgtgttagtg
    20701 ggtgctggaa aagagaaagc cgctctccag tctttggttg cagagaaaca attgcgtaat
    20761 atattcttta ttgaccccat tccaaaagtt gaaattcagt ctattttgag cgagtttgat
    20821 gcttgttaca tcgggcttac aaaagaccca ttattccgat ttggtgtctc acctaacaaa
    20881 ctatttgatt atctttattc aggtaagccg attgtttacg gtattgagtc tggtgagtat
    20941 aagccaatcg aagacgctaa ggcggggcta caagtcccgg cacaagctcc agagcaactg
    21001 gctgatgctg tcttaagcct ttatcagatg ccagcagaag aaaggctggc tatgggggaa
    21061 aatggccgta aagctgcact taagcagtat gagtacgggc aactggctaa tcaattgata
    21121 aaagtgttgt ttaactaagt gccttctgac aaggtaaccg catgaacatc cttgacttta
    21181 gatgtgcata ctttcagata aaaatcatca acacgcctat gtttaaaggg tgaattccat
    21241 agattggttg atctgttgga tagcgttatc acacaacaaa caattaaccg atgagcattt
    21301 tcagtgtttt ctaatatctc catagacaaa ttggaggtta aacaatgagt aaccagcacc
    21361 catttatgca tgttgacgcc atcccggatt acccttagta ctaagtctga agtgaaacga
    21421 cattgaaagc gattattaaa cataaaaggg tgatggatcc agagttcctt ttgaaggtat
    21481 tgggaagcct ttatttacga gaatgttcat gatttttacg tatagttctg aattttatag
    21541 gtagataatg aaaagggtat ttgatttcct gatttcactc gcggtgctca ttgttttatc
    21601 cccaatcact gtgctcgttg cttggaaaat acgttcaaac cttggctctc cagtgctttt
    21661 tcgccaaatc aggccgggtt taaatggtca gccttttgaa atgatcaagt ttcgtaccat
    21721 gaaagatgct gtggatgcta atggtaaccc attgccggac tctgaacgca tgactccttt
    21781 cggtgacaag ttgcgtaatt caagcttaga tgaattgcca gaactttgga atgtgcttaa
    21841 aggtgagatg agcttggttg gccctcgtcc attgctaatg caatatttac ctctgtatag
    21901 caaagagcaa gctcgtcggc atgaagtccg ccctggggta accgggtggg cgcaaattaa
    21961 tggtcgcaac gccataagtt gggaagaaaa attcaaactc gacgtttggt atgttgataa
    22021 tcactctttt tggctagatt taagaattct gctgttaact gtaaaaaagg tgtttgttaa
    22081 agaaggtatt tcggcggatg gtcacgtcac cattgcccca tttacaggga aagatcaaca
    22141 aggaacaggt aatgaacgtt aagcctgtga gtaaaaactc gttaggttct tgtgcaattc
    22201 tcggtgccag cgggcatggc aaggtgattg ctgaaatggc tgagctcaat ggctattctg
    22261 atatccattt ttatgatgac cgctggccaa gtctaggacg agtagagctt tggcaggtgt
    22321 caggcaatag tgaaacctta ctcaagcaag cgcggaatta tgctaatgtt gttgttgcta
    22381 taggcaataa cgcaactcgc ttagagaagt acaatcaact ggttgcgtct ggagctagct
    22441 gtctgccttt ggttcatccc tcagccatag ttagtcgata tgccaatgtg gaaaatggta
    22501 cggtagtgat ggctggtgcg gtgattaacc cgtttagccg tattgggcag gcctgcatta
    22561 ttaatactgc cgctacggta gatcacgatt gtgtcattga ggatggagtg catctgagcc
    22621 ctggtgtaca ccttgccggc ggtgtagaag tcgcacaagc tagttggctg ggaattggtt
    22681 gtcagattaa gcaattaatc aaaattggtt caaacgctgt tgttgcagca ggagcaacag
    22741 tgataaacga tgtattagcg aatcagatgg tggtaggtgt ccctgcaaaa cctatttgcc
    22801 ctaaggaatt ataactgtgt taaacacccc tttttctcct tggccgagtt tcactcaaga
    22861 agaggctgat gcagtaagta acgtgctgct ttctaacaaa gtcaattatt ggacgggtaa
    22921 cgagtgccgt gagtttgaaa atgaattcgc gacatgggca ggttgtgaat acgctattgc
    22981 tttgggtaac ggcaccttag cgcttgatat agccttaaaa gcgttgggtg ttggtgtggg
    23041 tgatgaagtg atcacgacct cgcgcacttt tttggcctct gcttctgcga ttgtcactgc
    23101 tggtgccaat cctgtatttg ctgatgttga tctcaacagc caaaatataa ctgctgaaag
    23161 cattgcggcc gtaatcactg aaaaaaccaa agcagtaatt gtggttcatt tagctggtat
    23221 gcctgcggaa atggatgcga tcatggcgct tgccgctgag cgtggttttt atgtgattga
    23281 agattgcgcc caagcacatg gtgcgagata caaaggccgc agtgtcggca ccattgggca
    23341 tattggtgct tggtccttct gccaagataa aattatgact actggtggtg aaggcggcat
    23401 ggtgacgaca aatgaccatg cgctctggtc gctgatgtgg tcctacaaag atcatggtaa
    23461 aagctatgat gctgtataca atcgtcagca cccgccgggc tttcgctggt tacatgaaag
    23521 ctttggtact aactggcgta tgactgagat ccaaggagta ttgggcagac ttcagctccg
    23581 gcgtatggct gagtggacag caaagcgtca atgtaatggt aagaagcttg accaagctgt
    23641 atctgattta gctgttgtac ggtgtgttca agtaccagac tacattgagc atgctgaata
    23701 caaacattac atgttcatta atcctgagca tctgaaagca gattggagcc gtgaccgtat
    23761 tatcgaaaaa attaatatgt taggtgttcc tgcttatcaa ggtagttgct ctgagattta
    23821 cttagagaag gcgtttgaca acacatcttg gcgtccagct caacgactta cgaatgcggt
    23881 tattttgggg gaaactagcc ttatgttttt agtccatccc actttgacta cccaagaaat
    23941 agagaaaagt tgtgatgtta ttaggagcgt tttaaccgaa gcaacgagat aaaataataa
    24001 tgaaatattc aaaggctaat acatggctag gctaaacttc atctggaatc tttcgcgtgt
    24061 aaataagcgc atcatcagcg ttttggtgga tgcgtttttt atcattttct cattttacag
    24121 tgcctattgg gttcgggtcg gaaactttga gattattcac tcagactcga taccttatct
    24181 tcttacaacg gttatcgttg ttacaatcct aagttttact cgacttgggt tgtatcgagc
    24241 tatcctacgt tacctcactt tccatgctct tgctgtggtg agtgttggca ccctaatttc
    24301 tacagcatct gttgctattg ccgcttttta ttttaatgca ccagtacccc gttctttgcc
    24361 tatcatctat ggcacctttt tgtgcctgtt gtgtggtggg tcgcgtttga ttgtgcgtgt
    24421 attggtttct gggctcaatg gtaaaggtcg taaagtcgtg ctgatttatg gtgcgggctc
    24481 tgctggtcgt caactagcga tagctttacg taactcagaa aactacaaag tggttgggtt
    24541 tatcgatcaa gataaaaccc ttgaaaatac cgtaatcatg ggtttgcaag tctatgatat
    24601 tagccgagct gcttacctcg ttgataagta cgatgttacc caggtgctac ttgcagtacc
    24661 gagtgcttca cgagcgcgta ggaagaagat tctcgagtca ttgatagact tgtcggcgga
    24721 agtgcttacg gttcctgata tgaaagatat cgttgaaggc aaggcatcca tcgatcagct
    24781 gaaagatgtg gcgattgaag acttactggg gcgcgatccg gtgacacctc agcaatgttt
    24841 aatggaatcg aatatcttag gtaaggtcgt catggtgaca ggggctggtg gttctatcgg
    24901 ctctgagctc tgtcgtcaga ttgtgcggca aaaacctaaa gcactagtgt tgtttgagct
    24961 ttcagagttt gggttatacc aaatcgatag agaactcaaa caactgatgg aagccgaggg
    25021 gctgcacgtt gaaatcatcc cgctactagg gtcggtacag agaatcaatc gccttgtggt
    25081 aacgatgaaa agcttcaagg tgcaaactgt ttatcatgct gctgcttata aacatgtacc
    25141 tcttgttgaa tacaatgtcg ttgaaggggt acgcaataac gtttttggca cttactacgc
    25201 tgcgcaggcg gccattgagg ccggtgttga atcgtttgtt ctgatctcca ctgacaaagc
    25261 ggtgcgcccg accaatgtca tgggaaccac caagcgtatg gccgaactgg gtttgcaagc
    25321 gcttgcggaa caagagaacc gtaaaaccaa aggaactcgc ttttgtatgg tgcgttttgg
    25381 taatgttttg ggctcatcgg gttctgtggt tccgctgttt aaacgtcaaa ttgaggcagg
    25441 cggcccaatt acggtgacgc acccagacat tattcgttat ttcatgacca tccctgaagc
    25501 ggcgcaactt gtgatccaag ccggagctat gggtaaaggt ggggatgtgt ttgtgcttga
    25561 tatgggtgag cctgtgcgca tcactgacct cgcggttaac cttattcagc tttctgggct
    25621 ggaagtgaaa gatgagcagc atccttatgg ggatattgcc attgagttca cagggttaag
    25681 gccaggtgag aagctctatg aagaactgct gattggcgat aatgttcaaa aaacggctca
    25741 tgagcgaatc atgacagcca atgaacgtta tttaccttta gcggaatttg aacagcatct
    25801 taacgagcta gacaaagcgt gtcatgcgtt taaccatgag cgtatccgtg agctattgct
    25861 tgaagcaccg accgatttta atccgacaga tgggattggt gacttagttt ggcagcgtac
    25921 gcaagataac caaactcagc ttgaaaaaca gtttgtgcat taatggtgtc gatttaagtt
    25981 gaaaaaccgc ggtctctacc gcggtttttt tatcctttcg attcatgctg gtgtgaaatc
    26041 ggtatgatcc catcggttga ttaatgtact caggagtgga aaacaacatg gaagtggttc
    26101 atcacggagg gaaggcgagt gtcacggg
//
