LOCUS       JX454603               20082 bp    DNA     linear   BCT 09-APR-2013
DEFINITION  Yersinia similis strain MW864-2 O-specific polysaccharide gene
            cluster, complete sequence.
ACCESSION   JX454603
VERSION     JX454603.1
KEYWORDS    .
SOURCE      Yersinia similis
  ORGANISM  Yersinia similis
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Yersinia.
REFERENCE   1  (bases 1 to 20082)
  AUTHORS   De Castro,C., Kenyon,J.J., Cunneen,M.M., Molinaro,A., Holst,O.,
            Skurnik,M. and Reeves,P.R.
  TITLE     The O-specific polysaccharide structure and gene cluster of
            serotype O:12 of the Yersinia pseudotuberculosis complex, and the
            identification of a novel L-quinovose biosynthesis gene
  JOURNAL   Glycobiology 23 (3), 346-353 (2013)
   PUBMED   23077132
REFERENCE   2  (bases 1 to 20082)
  AUTHORS   Kenyon,J.J., De Castro,C., Cunneen,M.M., Reeves,P.R., Molinaro,A.,
            Holst,O. and Skurnik,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2012) School of Molecular Bioscience, University
            of Sydney, Building G08, Darlington Campus, Sydney, NSW 2006,
            Australia
FEATURES             Location/Qualifiers
     source          1..20082
                     /organism="Yersinia similis"
                     /mol_type="genomic DNA"
                     /strain="MW864-2"
                     /serotype="O:12"
                     /isolation_source="river water"
                     /db_xref="taxon:367190"
                     /country="Japan"
     gene            227..1231
                     /gene="ddhD"
     CDS             227..1231
                     /gene="ddhD"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-6-deoxy-delta-3,4-glucoseen reductase"
                     /protein_id="AFV46128.1"
                     /translation="MWTYFMSLNVKLHPSGIIFTSDGTSTILDAALDSNINIEYSCKD
                     GTCGSCKAILISGEVDSAENTFLTEEDVAKGAILTCCSKAKSDIELDVNYYPELSHIQ
                     KKTYPCKLDSIKFVGEDIAILSLRLPPTAKIQYLAGQYIDLIINGQRRSYSIANAPGG
                     NGNIELHVRKVVNGVFSNIIFNELKLQQLLRIEGPQGTFFVREDNLPIVFLAGGTGFA
                     PVKSMVEALINKNDQRQVHIYWGMPAGHNFYSDIANEWAIKHPNIHYVPVVSGDDSIW
                     TGATGFVHQAVLEDIPDLSLFNVYACGSLAMITAARNDFINHGLAENKFFSDAFVPSK
                     "
     misc_feature    227..19730
                     /note="O-specific polysaccharide gene cluster"
     gene            1257..2042
                     /gene="ddhA"
     CDS             1257..2042
                     /gene="ddhA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate cytidyltransferase"
                     /protein_id="AFV46129.1"
                     /translation="MEIQVKAVILAGGLGTRLSEETVVKPKPMVEIGGKPILWHIMKL
                     YSSYGINDFVICCGYKGYVIKEYFANYFMHMSDITFCMRDNEMTVHQKRVEPWNVTLV
                     DTGEDSMTGGRLRRVKDYVKDDEAFCFTYGDGVSDVNIAELIEFHKSHGKQATLTATY
                     PPGRFGALDIKDKQVRSFKEKPKGDGALINGGYFVLSPKVIDLIDGDKSTWEQEPLMT
                     LAAQGELMAFEHAGFWQPMDTLRDKIYLHELWEEGRAPWKVWE"
     gene            1939..3120
                     /gene="ddhB"
     CDS             1939..3120
                     /gene="ddhB"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose-4,6-dehydratase"
                     /protein_id="AFV46130.1"
                     /translation="MNMPGSGSQWIRCVTRSICMNYGKKAGHLGRYGNNKMINNSFWQ
                     GKRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLAPPTVPSLFDTARVADGMQSEIGDI
                     RDQNKLLESIREFQPEIVFHMAAQPLVRLSYTEPVETYSTNVMGTVYLLEAIRHVGGV
                     KAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYRNSFFNPSSYD
                     QHGTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPVIIRNPHAIRPWQHVLEPLS
                     GYLLLAQKLYTDGAEYAEGWNFGPNDADATPVKNIVEQMVKYWGEGASWQLDGNAHPH
                     EAHYLKLDCSKAKMQLGWHPRWNLNTTLEYIVGWHKNWLSGTDMHEYSITEINNYMNT
                     K"
     gene            3138..4451
                     /gene="ddhC"
     CDS             3138..4451
                     /gene="ddhC"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-4-keto-6-deoxy-D-glucose-3-dehydratase"
                     /protein_id="AFV46131.1"
                     /translation="MSQEELRQQIAELVAQYAETAMAPKPFEAGKSVVPPSGKVIGTK
                     ELQLMVEASLDGWLTTGRFNDAFEKKLGEYLGVPYVLTTTSGSSANLLALTALTSPKL
                     GVRALKPGDEVITVAAGFPTTVNPTIQNGLIPVFVDVDIPTYNVNASLIEAAVSDKTK
                     AIMIAHTLGNLFDLAEVRRVADKYNLWLIEDCCDALGSTYDGKMAGTFGDIGTVSFYP
                     AHHITMGEGGAVFTQSAELKSIIESFRDWGRDCYCAPGCDNTCKKRFGQQLGSLPFGY
                     DHKYTYSHLGYNLKITDMQAACGLAQLERIEEFVEKRKANFKYLKDALQSCADFIELP
                     EATENSDPSWFGFPITLKEDSGVSRIDLVKFLDEAKVGTRLLFAGNLTRQPYFHDVKY
                     RVVGELTNTDRIMNQTFWIGIYPGLTHDHLDYVVSKFEEFFGLNF"
     gene            4487..6202
                     /gene="yerE"
     CDS             4487..6202
                     /gene="yerE"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-yersiniose biosynthesis protein"
                     /protein_id="AFV46132.1"
                     /translation="MFLGQKMKASDAIAHVLSANNVDFGFELIGGMIAHLVDSINSLG
                     KTKLVSVHHEQAAAFAAGGIARATGNEKIGLALGTSGPGATNLITGIADCWLDSSPCI
                     FITGQVNTHELKGGRGIRQQGFQELDIVSIVKSITKYAYQIKSKDEIIPCLQNAIDIA
                     RSGRPGPVLIDIPMDLQRAELDDSIINYLNNEIDSNLISKKDSSSIFDEIFSLLEQSK
                     RPVFLIGGGAIHEEKFNLWQNKISENNIPHVASLKGAEKTLSIPGYFGMVGSYGTRTA
                     NYAVQNADLVIVLGSRLDVRQTGADTQDFARNAKIVQIDIDIEQLDNRVKCQLNINAS
                     CEDFFSYYLRSRQCNSYNSWFLQLENNWTKNFVDEYQDLKVSPFSLFSILNNAFNDKN
                     VHYVTDVGNNQMWAAHSLRLGVGQAIHNSGGLGAMGFGIPTAIGVSYATNYPVVVITG
                     DGGAQLNIQELDIISRENRPILTIVLNNNSLGMVRAFQEMYFDGRNESTYWSGYSSSF
                     SKIGKAYNVESYTVLTECDFLEKVNVFIDNPKPMLIEVLMEDARECRPRLAFGNPIDK
                     QFPYK"
     gene            6215..7159
                     /gene="yerF"
     CDS             6215..7159
                     /gene="yerF"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-yersiniose biosynthesis protein"
                     /protein_id="AFV46133.1"
                     /translation="MKLAIFGATSQIAKDLIIRLSGLQDIKLYLYSRNPVLVEEWASK
                     LRSRNKINSYHFAEFCSNQQYDGIINFIGASDPEKIKLINSDILKITNEYDSIIINYL
                     NVHIECKYLFISSGAAYGDVFSTENHDRTYSKFKLDNQSVSDWYGIAKYCTEMRHRSL
                     YQFNIYDIRVFSYFSASQNIEANFILSEMYRKIRDNSIFYTTDQNIVRDFIHPDDFYQ
                     LVCSVLFNDIKNCVLDCYSAEPITKKELILLMHDEFGMEYNIKKNSKLISTSASKVFY
                     YSKNKSAGGLLGYIPRYTSKESIVMEMSKIIKNIKHHD"
     gene            7152..8498
                     /gene="wzx"
     CDS             7152..8498
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AFV46134.1"
                     /translation="MTKIKYLALKLSKLTSIDYHIGITLLLRLWTIVAGGILILLVPI
                     FFTENEQGYYFTFASLISLQVFFELGFNYVIVQMVGHEMAYIKINKYKQLEGQPSSIS
                     RVYSLIALLKKWYLFISLLFLIIVFISGFYFFKINGPLDIYIWLPAWSILVVFSSVNL
                     FVSPQLAVLEGMGFVGQVAMIRLYQSLIGYILFFILISSGGGLLAVSIISGSSAFISL
                     MFITVKYKNILYRKNHIYSDRISWRKEIFPFQWKIALSWMSGYFIFQLFNPILFVHQG
                     AIEAGRVGLTLQIFSTMLALSMSWITAKSPVMARLIAENNRVELNKLFFSLIIKSGIL
                     NIIMSFLFLLFIYVFRLYDFNIVTRVANISVILVLCFTSIINHLVFSMAIYMRAHKEE
                     PMLWNSITVGIIIIPLIYLFSKISSFLTIFSYFMVMVVVCLPWCYVIFKKYYNRKL"
     gene            8527..9528
                     /gene="wbzH"
     CDS             8527..9528
                     /gene="wbzH"
                     /note="putative CDP-yersiniose glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFV46135.1"
                     /translation="MNSSLIINNCSLIEGDVILTIAIPTYKRFSLLKETLRSVFDLKF
                     NIPIEVIIVDNDPENIDLAIKEMQEFLGYKFKYYKNESNYGAAGNWNRCLELAIGQFI
                     TLLHDDDLLCENFPYEIESYFNSLEKLECAPMIGFDAHVLEQRDACSKVKVGFIYTLV
                     KNIYQKYKNMRTMNDYQFKDLQSFIFSGSYVSTLGVVMDRKKALAISGFDNSWYPVID
                     CEFYIRWIRAYGDVIYKNVKVSKYRILQNDSMKQEVIRDVIKKSYELRMKVHNEEHNL
                     VGIDKFAKIMKKIEDYTWNMKWRKGNEYKINILDVAKLLLLKLNCILHIRKINLMRK"
     gene            9559..10650
                     /gene="wzy"
     CDS             9559..10650
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AFV46136.1"
                     /translation="MIFYILATALLIISLFDLIFPNIRGVGYRYIYSCFLVFLAIFCG
                     LRSNTVDYDYIEYVRIYNNIPSLFDLFSDGLKDIHGDALFFLISSLVKSLNLDVYVVF
                     MVFAFSSIFIYRWCLLNFSVYPFLSIFIYFCHGFLNKEMTQIRAGLASAFILISLCFF
                     CERKKTKSFITMILSFLSHSSALPVVLLNTCNFFLKEKHYRVIVLFFLSVGLFFIWEP
                     LFNILPENISIVKNVNNYVYWDKYNYSLSLLNPVLLKQLFYVFIFIYMRDKYKWPSNM
                     NIFIFSYVFSVCWLIAFSDMAILASRISNLFSVSELILVPYAIKTFFINKKPIFGLGL
                     FFITIIINFAMLYNNLEIKKIFFDYQTIL"
     gene            10674..11726
                     /gene="wbzI"
     CDS             10674..11726
                     /gene="wbzI"
                     /note="putative glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFV46137.1"
                     /translation="MKIAMITPSLRNVGPVKVALDIITELVDGDSALDISFTVFYLDE
                     KVEVSFPCQQVKLTWRNILELYDYDVIHSHMLRPDLLNSLLPFYKGMKISTIHNIVKT
                     DLLFSHGKTVSFLFSNVWKLIWKGIHKKVVLTNYAKKYYSNEMSIPLDEITVINNGVK
                     KIEKPDSFSGDLAEKIGFFKEKKYIVLGSVALFNDRKGLEQVIKLLVKKTDYAYVIIG
                     DGPSKNYLKKLAEECEVSNRVFFSGFMHNGKDYIYMLDCYMMPSREEGFPLALTEAIS
                     TNVVTVCSDIPVFKEILDEASTSYFALDDINSLSLAVERSISNRVALSASAYKKYCLE
                     YTREIMAKKYVELYMH"
     gene            11772..12755
                     /gene="qui"
     CDS             11772..12755
                     /gene="qui"
                     /note="putative L-quinovose biosynthesis protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Qui"
                     /protein_id="AFV46138.1"
                     /translation="MVNMNKVLVTGGSGFIGTNVVSRLLDMKYHVLNIDIKPPIKSEH
                     LFCYKYIDMKSFSQLREAIADFEPNMILHLAARTDLNGKKLSDYEDNIIPVENLCKII
                     TNSPFVNRVIFTSSMLVCRAGYIPADSEDYCPTTVYGESKVETENIVKKYKNLLPSFC
                     IVRPTSIWGPWFKEPYRDFFDMVLAGRFFRIGKPSCTKTYGYVGNTVNQIISLLSFKE
                     EKSNDNVYYLGDSPPNNIDDWSVKISELAEKRKPIILPFFLLKVAALIGDLLISVGVK
                     FPLSSFRLKNMTTNNVLDCTKVISCNKWEPIPLEHGIKATLNWMKEYKVMK"
     gene            12725..13870
                     /gene="gmd"
     CDS             12725..13870
                     /gene="gmd"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="AFV46139.1"
                     /translation="MDERIQGNEMKKALITGITGQDGSYLAEFLLEKGYEVHGIKRRA
                     SSFNTSRIDHIYQDRHETNPRFFLHYGDLTDTSNLIRLVQEIQPDEIYNLGAQSHVAV
                     SFESPEYTADVDAMGTLRLLEAIRINGLEKKTRFYQASTSELYGLVQETPQRETTPFY
                     PRSPYAVAKMYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAVANIAL
                     GLEKCLYLGNIDSLRDWGHAKDYVRMQWMMLQQDKPEDFVIATGKQITVREFVRMSAR
                     EAGIELEFSGEGVDEVATVVAVNGNHVSSVNIGDVIVRVDPRYFRPAEVETLLGDPTK
                     AKKVLGWVPEITVEEMCAEMVASDLEQAKQHALLKANGFDVSISSEN"
     gene            13849..14841
                     /gene="fcl"
     CDS             13849..14841
                     /gene="fcl"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthetase"
                     /protein_id="AFV46140.1"
                     /translation="MHFVGELIQMDKKRVFIAGHRGMVGSAIVRQLKNRNDIELIIRD
                     RTELDLMSQSDVQKFFATEKINEIYLAAAKVGGIQANNNYPAEFIYENLMIECNIIHA
                     AHLADIQKLLFLGSSCIYPKLAAQPMIEEALLTGVLEPTNEPYAIAKIAGIKLCESYN
                     RQYGRDYRSVMPTNLYGENDNFHPENSHVIPALLRRFHEAKIRNDKEIVVWGTGKPMR
                     EFLHVDDMAAASVHVMELSDQIYQTNTQPMLSHINVGTGVDCTIRELAETMAKVVGFT
                     GNLVFDSTKPDGTPRKLMDVSRLAKLGWCYRISLEVGLTMTYQWFLAHQNNFRK"
     gene            14994..16406
                     /gene="manC"
     CDS             14994..16406
                     /gene="manC"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="AFV46141.1"
                     /translation="MLMLLPVIMAGGAGSRLWPLSRALYPKQFLALTSDLTMLQETLL
                     RLDGLPHLAPLVICNEEHRFIIAEQLRQKNLVHSGILLEPVGRNTAPAIALAALRATM
                     SGDDPLLLVLAADHVIQDKLAFIRAVQLAEPLAEAGKLVTFGIVPKSPETGYGYIRQG
                     KQVVDGAYQVAAFVEKPDLITAERYLASGDYYWNSGMFVFKASRYLQELDLHRPDILA
                     ACKQAIAGQHTDLDFIRLNEEAFSSCPGESIDYAVMEKTSDAVVVPMDAQWSDVGCWS
                     ALWDINTKDGHGNVIRGDVLMEDTNNSYVYSQNRLIATVGINDLVIVETKDAILVAHK
                     DKVQDVKGIVGQLKLESRCEYLQHREVYRPWGAHDAIAKGVRYHVQHVTVKPGQRIAT
                     QIHYHRAEHWVVVSGIAKVHYGKETYLVNENESTYIPVGIAHSIENPGQIPLEIIEVH
                     TGNYISEDDVERIDDLGVGY"
     gene            16406..17152
                     /gene="wbyL"
     CDS             16406..17152
                     /gene="wbyL"
                     /note="putative glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AFV46142.1"
                     /translation="MMKISIITATYNSERTISDTLSSLEKQTYLDVEYIIVDGASKDN
                     TLTVISQNSTRVTKIISESDQGIYDALNKGIDLATGDIIGFLHSDDLLAYPGALSDIV
                     ETFEKQQCDAVYGDLQYVAKNDLNKVIRCWKSVFFNHEKMKYGWMPPHPTFYMKRDLY
                     IRFGGFDLSYKISADYDSLTRYIINYKIKVAYLPKVIIKMRVGGISNRSLGSMLLKSK
                     EDIQIMKLRGLFWPMSFLCKNLSKLPQFIK"
     gene            17157..18529
                     /gene="manB"
                     /pseudogene="unknown"
     gene            18579..19730
                     /gene="wzz"
     CDS             18579..19730
                     /gene="wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant"
                     /protein_id="AFV46143.1"
                     /translation="MSNKQTQSNLDNPIPNNYDFSNISSSKNEIDLFELFGIIFSSKL
                     KIIFITFVFIIIGLGISYILPQKWTSTAIIALPGDEQVQVLDELVTNLTVLDIKVDVS
                     ANYLLSTFKQNFDSQDLREQYLVNTNYFKRLLKDNPEDGLDKRALIERIVNENISSVN
                     PVKDKTEGDNEYRYYKLSYSASTPTDARDLLQGSINYINTIVNADVFRKIQRAVDLAK
                     GIGTDKYSMELLKARNNQKVKIERLRYASSIADAAGVKKPVYSSGSAISDDPDFPITM
                     GSDALNRKLEIEKSVTDLASINAELLNRKLYLDKLNRLEIPNVNIVPFKYLQQPTEPT
                     KRDAPKRALIVILFALVGLMGSVGFVLVEHFVRGRKREEEGLKLSQTKE"
BASE COUNT     6164 a   3108 c   4098 g   6712 t
ORIGIN
        1 attggtagct gcaagccaag ggcggtagcg tgggggggat agaaccccaa tagttgcctt
       61 ttactctgga aacggcagga agaagacctt ctacaatttt ttactttagg gatttttaac
      121 cgtacttcta tatcaaaaat tatttgcttt tttgtttcta ttttagtcac tgaatttttt
      181 tgacttaagt ttgtattgag tacgtctaat aaaccttaca taatatattt ggacttattt
      241 tatgtcatta aatgttaagc tgcatccatc aggtattatt tttacttccg atggaacatc
      301 tacaatatta gatgcggctc tggatagtaa tataaatatt gaatacagct gcaaagatgg
      361 aacctgtggt tcttgtaagg caatattgat ttctggtgaa gtagacagtg cggaaaatac
      421 ctttttaact gaggaagatg ttgctaaagg tgcaattcta acttgttgct ctaaggcgaa
      481 atctgatatt gaattagatg ttaattacta tccagagtta agtcatatac aaaaaaaaac
      541 ttacccatgt aaattagata gcattaaatt tgttggtgaa gatattgcca ttctctcctt
      601 acgcttgcca ccaacggcca aaatacagta tctggcgggc caatacattg atttaattat
      661 taatggacag cgccgtagtt actctattgc taatgctcca ggtggtaatg gcaatatcga
      721 attacacgta cgtaaagttg ttaatggtgt attcagcaac atcattttta atgagttaaa
      781 attacagcag cttttgcgaa ttgaaggccc gcaagggacc tttttcgttc gtgaagataa
      841 tctccctatt gtttttcttg ctggtggaac aggttttgca ccagtgaaat caatggttga
      901 ggcgttgatc aataagaatg accaacggca ggttcatatc tattggggaa tgcctgcagg
      961 gcataatttc tattctgaca ttgccaatga gtgggctata aaacacccta acattcatta
     1021 tgtgcctgtt gtatcaggcg atgatagtat ttggaccgga gccactggtt ttgtacatca
     1081 agcggtgctt gaagatatac ccgatctcag tttatttaat gtttatgcct gtggttcatt
     1141 agctatgatt actgctgctc gtaatgattt cattaatcat ggattagctg aaaataaatt
     1201 tttctctgat gcctttgtgc catcaaaata actttgagag atcaaagtaa tacgtaatgg
     1261 agattcaagt gaaagcagtc attttggccg gaggccttgg aacccgtctt agtgaagaga
     1321 ccgtagtaaa accaaaacca atggtagaga tcggtgggaa gcctattctc tggcatatta
     1381 tgaaacttta ctcttcttat ggcataaatg atttcgttat ttgctgtggc tataaaggct
     1441 atgtcattaa agaatatttt gcgaattact ttatgcacat gtcggatatt accttctgca
     1501 tgcgtgataa tgaaatgaca gtacaccaaa agcgagtcga accttggaat gtcacgttag
     1561 tagacaccgg tgaagattct atgaccggtg gccgacttag gcgtgtaaaa gattacgtca
     1621 aagacgatga ggctttctgt ttcacctatg gtgatggtgt tagtgacgtt aatattgctg
     1681 aattaattga attccataag agccatggca agcaagccac attaacggca acctatcccc
     1741 caggccgttt tggtgcgctg gatattaaag ataaacaagt acgtagtttt aaagaaaaac
     1801 caaaaggcga tggcgcattg atcaacggcg gttattttgt tttgtcgcct aaagttatcg
     1861 atctgatcga tggtgataag tctacttggg agcaggaacc tttaatgaca ttagctgcgc
     1921 agggggagtt gatggcgttt gaacatgccg ggttctggca gccaatggat acgttgcgtg
     1981 acaagatcta tctgcatgaa ctatgggaag aaggcagggc accttggaag gtatgggaat
     2041 aacaaaatga ttaataatag tttctggcaa ggtaaacggg tttttgtaac cggtcatact
     2101 gggtttaaag gtggctggtt gagtttatgg ttgcaaacca tgggggcaac ggtaaaaggt
     2161 tactctctgg ccccccccac tgtgcctagc ctatttgata ccgcacgagt tgccgacggg
     2221 atgcaatcgg aaatcggtga tattcgtgat caaaacaaat tattagaatc aatccgcgaa
     2281 ttccagccag agattgtttt ccacatggct gctcagccac tggtcaggtt atcctacacc
     2341 gagcctgttg aaacctactc aacgaatgtt atgggtaccg tttatttact ggaggctatt
     2401 cgccatgttg gtggcgtcaa ggcggtggtc aatatcacca gtgataaatg ctacgataat
     2461 aaagagtgga tctggggcta tcgcgaaaat gaagcgatgg ggggatatga cccttactct
     2521 aacagtaaag gttgtgcgga attagtgacg tcatcctatc gtaattcgtt cttcaatcca
     2581 tcgagctatg accagcatgg cactgccgta gcgacagtac gtgctggtaa tgttatcggt
     2641 ggtggcgatt gggcattgga tcgcatcgtt ccagatatcc ttcgggcgtt tgaacagtcc
     2701 caaccagtga ttattcgcaa cccacatgcc attcgcccat ggcagcatgt gttggagcct
     2761 ttgtcgggtt atttgctgtt ggcacagaag ttatatactg acggtgctga atatgccgaa
     2821 ggttggaact ttggtcctaa cgatgctgat gctactccag taaaaaacat tgttgaacaa
     2881 atggtgaaat attggggaga gggggcaagc tggcaattag atggcaatgc tcaccctcat
     2941 gaagctcatt atctgaaact ggattgttca aaagctaaaa tgcaactcgg ttggcatcct
     3001 cgctggaact tgaatactac gctcgaatat attgtgggct ggcacaagaa ctggttatca
     3061 ggcacagata tgcatgaata cagtattact gaaattaata attacatgaa cactaaatga
     3121 tttgaggtca tagataaatg agtcaagaag aattacgtca acagattgct gagctggttg
     3181 ctcagtacgc tgaaacggct atggccccta agccatttga agcaggtaag agtgtcgttc
     3241 caccttcagg taaagttatt ggtaccaaag aactccagtt aatggttgaa gcttctttag
     3301 acggttggct aacaacgggc cgttttaatg acgcttttga gaaaaaacta ggcgagtact
     3361 tgggcgttcc ttatgttctg actacaactt ccggctcttc agctaactta ttggctttga
     3421 ccgcgctgac ttcccctaaa ttaggggtac gggcgttgaa accaggtgat gaagttatta
     3481 ctgtggccgc cggttttcca actacagtaa acccaactat tcagaatggg ttaattcctg
     3541 tatttgttga tgttgatatt ccaacttaca atgtgaatgc cagcctgatt gaagcggcgg
     3601 ttagtgataa aactaaagct attatgattg cccatacatt aggtaatcta tttgatctag
     3661 ctgaagttcg ccgagtagct gataaatata acctgtggtt aattgaagac tgctgcgatg
     3721 cgttgggctc tacctacgat ggaaaaatgg caggtacgtt tggcgatatt ggtaccgtta
     3781 gcttctatcc tgctcatcat atcaccatgg gcgaaggtgg ggcggtattt acacaatcgg
     3841 cggaactgaa gagtatcatc gaatctttcc gtgattgggg tcgtgattgt tactgtgctc
     3901 caggctgtga caacacatgt aaaaagcgtt tcggccagca actaggctct ttaccattcg
     3961 gttatgatca taaatatact tattcccatt taggttataa cctaaaaatc acagatatgc
     4021 aggctgcctg tggcttggcg caactagagc gcatagaaga gtttgttgaa aaacgcaaag
     4081 ctaactttaa atatcttaaa gacgcacttc aatcctgtgc tgactttatt gaattaccag
     4141 aagcaactga aaattcagat ccatcatggt ttggtttccc tatcacactg aaagaagata
     4201 gcggagttag ccgtattgat ctagttaaat tccttgatga agctaaagtg ggaactcgcc
     4261 tactctttgc cggtaattta actcgccagc cgtatttcca tgatgtgaaa taccgtgttg
     4321 ttggtgaatt gacaaatacc gatagaatta tgaatcaaac tttctggatt ggtatttacc
     4381 caggcctgac acatgatcat ttggattatg ttgtgagtaa gtttgaagag ttctttggtt
     4441 tgaattttta atgtagttag tatattgagc tggtttagct agcttaattt ttctggggca
     4501 gaaaatgaaa gcatctgatg caatagcgca tgtgttaagt gctaataatg tagattttgg
     4561 ttttgaattg atcggtggaa tgattgctca tcttgtggat agcatcaatt cattagggaa
     4621 aacaaaatta gtttctgtac accatgagca ggctgcagca tttgcagccg gtggaatagc
     4681 tagagctacg ggtaatgaaa aaataggttt agctttaggt actagtggac ctggtgctac
     4741 aaatttgata actggcattg cagattgttg gttagatagt tctccttgta tttttattac
     4801 aggccaggtc aatactcatg aacttaaggg ggggcgtggt atccggcagc aaggttttca
     4861 agaattagat atagttagta ttgttaaaag tataacaaag tatgcatatc agataaaaag
     4921 caaagatgaa ataattccat gtttgcaaaa tgcaatcgat atcgcaagaa gtggtagacc
     4981 tgggcctgtg cttattgata tcccaatgga tctgcaaaga gctgaactag atgatagtat
     5041 aatcaattat cttaacaatg aaatagattc taatctgata tctaaaaaag attcatcatc
     5101 tatatttgat gagattttta gcttactaga gcagtctaaa cgacctgtat ttttaattgg
     5161 tggtggtgca atacacgaag aaaaattcaa tctttggcaa aacaaaattt ctgaaaataa
     5221 tataccccat gtcgccagtt taaaaggtgc ggagaaaact ttatcaatac caggctattt
     5281 tggtatggtc ggtagctatg gtacccgcac tgctaattat gcagtacaaa atgctgactt
     5341 ggttattgtt ctaggtagcc gtttagacgt aaggcagacc ggtgctgaca cgcaagattt
     5401 tgcaagaaac gcgaaaattg tccaaattga tattgatatt gaacaattag ataatagagt
     5461 gaaatgtcaa cttaatatta atgcatcatg tgaggatttc ttttcttatt atttacgttc
     5521 gaggcaatgt aattcgtata actcttggtt cctacaatta gaaaacaatt ggactaaaaa
     5581 ttttgtagat gaatatcaag atttaaaagt aagtccattt agccttttct ccattctaaa
     5641 taatgctttt aatgataaaa atgtccatta cgtaactgat gtcggcaaca atcagatgtg
     5701 ggcagcccat tcattacgtt taggtgtagg gcaagctatt cataattctg gaggcttggg
     5761 tgcgatggga tttggcatcc caacagctat tggtgtgtca tatgcgacaa actatcctgt
     5821 tgtagtaatt actggggatg gtggagctca attgaatatc caagagctag atattatatc
     5881 tcgcgaaaat cgtcctatac taacaatagt tttaaacaat aattctttag gtatggtacg
     5941 tgcttttcag gaaatgtatt ttgacggtag aaatgagtca acatactgga gtggatatag
     6001 ctcatcattc tctaaaattg ggaaagcata taatgttgag tcgtacactg tattaacaga
     6061 atgtgacttt ttagaaaaag tcaatgtgtt tattgataat ccaaagccaa tgcttattga
     6121 agttttgatg gaagatgcaa gagaatgtag accaagatta gcttttggta acccaattga
     6181 caaacaattc ccctataaat aaccggttta atatatgaag ttagcaattt ttggtgcaac
     6241 gagtcagata gctaaagatc tcattatacg tttatcaggt ttacaagata taaaattata
     6301 tctatattcc agaaacccgg tgttagttga agaatgggca agtaaattaa gatcaagaaa
     6361 taaaataaat tcctatcact ttgctgaatt ttgttctaac caacaatatg atggaattat
     6421 aaatttcata ggtgcctctg atcctgaaaa aataaaattg attaatagtg atatacttaa
     6481 aataactaat gagtacgatt cgattataat taattatctg aatgttcata ttgaatgcaa
     6541 atatttattt attagtagtg gtgctgctta tggcgatgtt ttttctactg agaatcatga
     6601 taggacatat tctaagttca agcttgataa tcaatcagtt tcggattggt atggaatagc
     6661 taagtattgt acagaaatga gacatcgctc tttatatcaa tttaatatat atgatataag
     6721 agtttttagc tactttagtg catcacaaaa tatagaggct aattttatat tatccgaaat
     6781 gtataggaaa attagggata attcaatatt ttacacaact gatcagaata tcgttaggga
     6841 ttttattcat ccggatgatt tttatcaatt ggtgtgtagt gtcttattta atgatataaa
     6901 aaactgtgta ttagattgtt actctgcaga acctataaca aaaaaagaat tgatattatt
     6961 aatgcatgat gaattcggca tggaatataa tattaaaaag aacagtaaac ttatatcaac
     7021 tagtgcttct aaagtttttt attatagtaa aaataagtcc gcaggtggat tgctaggcta
     7081 tattcctaga tacacatcta aagagtcaat tgtaatggaa atgtctaaaa taattaaaaa
     7141 tataaaacac catgactaaa ataaaatatt tagcattaaa gttatctaag ttaacttcca
     7201 tcgattatca tataggtatt acattattac ttcgtttatg gactatagtt gctggtggaa
     7261 ttctaatttt attagttcct atttttttta cagaaaatga acagggatat tattttacat
     7321 ttgcaagttt aatttcatta caggtttttt ttgaacttgg ttttaattat gtcattgtcc
     7381 aaatggtggg gcatgagatg gcatatataa aaataaataa atataaacag cttgaaggac
     7441 agccatcaag tatatcacgt gtttattctc ttattgcttt attaaaaaaa tggtatttgt
     7501 ttatatcgct attgttctta attattgtat ttatctctgg cttctacttt tttaaaataa
     7561 atggtcccct tgatatatat atatggttac ctgcatggag tatcttagtt gtcttttcgt
     7621 cagttaatct ttttgttagc ccacagttag ccgtacttga ggggatgggg tttgtcggcc
     7681 aagtggcaat gattcgccta tatcaatcgc ttattggtta tattctattt tttatattaa
     7741 tttcaagtgg tggtggatta ttagcagtat ctataattag tggttcttca gcttttattt
     7801 cattaatgtt tatcacagta aagtataaaa atattttata cagaaaaaac cacatatata
     7861 gtgatagaat ttcttggcgg aaagaaattt ttccatttca atggaaaatt gctttgagtt
     7921 ggatgagtgg gtactttatt tttcagttgt ttaaccctat tctttttgtt caccaaggag
     7981 ctattgaggc tggaagggtt ggtttaacac ttcaaatatt tagtactatg ttggcattat
     8041 ctatgagttg gataacagca aaaagtccgg tgatggctag attgatagcg gaaaataata
     8101 gagttgagct aaataaatta tttttctctc ttataataaa atctggtatt ttgaatatca
     8161 ttatgtcatt tttattttta ttgtttattt atgtttttag actatatgat tttaatatag
     8221 taactagagt ggcgaatata agtgttattt tggttttgtg ttttacatct atcattaatc
     8281 atcttgtttt ttcaatggct atttatatgc gtgctcataa agaggaacca atgctgtgga
     8341 attctataac agtaggaata atcatcattc ctcttattta tctattttct aaaataagtt
     8401 catttctaac tatattcagt tattttatgg ttatggttgt agtttgctta ccttggtgtt
     8461 acgttatttt taaaaaatat tacaatagaa aattataaat attaatttta actttaaggt
     8521 ttataaatga atagtagtct cattattaat aattgttctt tgattgaagg tgatgttatc
     8581 ttaacaatcg caattcctac ctataaaagg ttttctttac taaaggaaac tttacgaagt
     8641 gtatttgatt taaagtttaa tattccaata gaggtcatta ttgttgataa tgatcctgaa
     8701 aatattgatt tggccattaa agaaatgcaa gaatttttag gctataaatt caagtattat
     8761 aaaaatgaat ctaactatgg agccgcgggt aattggaatc gttgcctaga gttagctata
     8821 ggacagttca ttactttatt acatgatgat gatttgttgt gtgagaattt cccctatgaa
     8881 attgagagtt attttaatag tttagaaaaa ttagagtgtg ctcctatgat tggatttgat
     8941 gcccacgttc ttgagcaaag agatgcgtgt agtaaagtaa aagtaggttt tatttataca
     9001 cttgtaaaaa atatatatca aaaatataaa aatatgcgaa caatgaatga ctaccaattt
     9061 aaagatctcc agagtttcat ttttagtggt agttatgtat ctacacttgg ggttgttatg
     9121 gaccgaaaaa aagcattagc gatctctggg tttgataatt cgtggtatcc tgttattgat
     9181 tgtgagtttt atatccgatg gataagagct tacggtgatg ttatatataa aaacgttaag
     9241 gtgtcaaaat acagaattct acaaaatgat agtatgaaac aagaagtaat tagagatgtt
     9301 attaaaaaga gttatgagct aagaatgaaa gttcataatg aagagcataa cttagttggc
     9361 atcgataaat ttgctaaaat tatgaagaaa attgaggatt acacctggaa tatgaaatgg
     9421 agaaaaggta atgaatataa gataaatata ctagatgttg ctaaactact tttacttaaa
     9481 cttaattgca tattgcatat aagaaaaata aatctcatga gaaaatgata atgtttgata
     9541 ttgttttggt gaaatttaat gatattttat attcttgcta cggcactgtt aattattagt
     9601 ttgtttgatc tgatatttcc aaatattaga ggtgttggat atcgatatat atattcatgt
     9661 tttttggttt ttttggctat tttttgtgga ctaagatcta atactgtcga ttatgactat
     9721 atagaatatg ttcgtattta taataatatt cctagcttat ttgatttatt ttctgatgga
     9781 ttgaaagata ttcatggaga tgccctattt ttcttaatct cttccctagt gaaatcttta
     9841 aacttagatg tatatgttgt ttttatggtt tttgccttct cctcaatatt tatttatcgc
     9901 tggtgtctgt taaatttttc agtttatcca tttttatcga tttttattta tttctgtcat
     9961 ggttttttaa ataaagaaat gacgcagatt agggccggtt tggcttcggc ttttattctt
    10021 atttctctgt gttttttctg tgaaagaaaa aaaacaaaaa gttttataac aatgatttta
    10081 tcttttctat cccactcatc agctctaccg gtagtattat taaatacatg caatttcttt
    10141 ttgaaagaaa aacattacag ggtaatagta ttgttttttt tatctgtagg tctttttttt
    10201 atttgggaac cattgtttaa tattttgcct gaaaatatat caatagtgaa aaatgttaat
    10261 aattatgtct attgggataa gtataactat tctttatcat tattgaatcc ggttttattg
    10321 aaacaattat tttatgtttt tatttttatt tacatgagag ataaatataa atggccatcc
    10381 aacatgaata tattcatttt ctcttatgtg ttttcagtct gttggctaat tgcatttagt
    10441 gatatggcca tacttgcatc tagaatatca aatttatttt cagtgtcaga actaatactc
    10501 gttccatatg caataaaaac tttttttatt aataaaaaac caatttttgg tttggggttg
    10561 ttttttatta ctataataat aaactttgct atgttatata ataatctgga aattaaaaaa
    10621 atattttttg attaccagac tattctgtaa gttgaaataa aagagagagc ataatgaaaa
    10681 ttgcaatgat aacaccatct ttaagaaatg ttggaccagt aaaagtagcc ttggatataa
    10741 taactgaact ggttgatggt gattctgcgt tggatatttc atttacagta ttttatttag
    10801 atgaaaaggt tgaagtttct tttccttgtc aacaggtaaa gttgacgtgg cgtaatatac
    10861 ttgaattata tgattatgat gtaattcatt cgcatatgtt aaggcctgat ttattaaact
    10921 cattattacc attttataaa ggaatgaaaa tctccacaat acataatatt gttaaaactg
    10981 atttgctttt ttctcatgga aagacggttt cttttttgtt ttcaaatgtt tggaaattaa
    11041 tctggaaagg tatacataaa aaagttgttt taactaatta tgcaaagaaa tattattcca
    11101 atgaaatgtc tattccactt gatgaaatca ctgttatcaa taatggtgtt aaaaaaatag
    11161 aaaaaccgga ttcattttct ggtgatttag ctgaaaaaat tggttttttt aaagaaaaaa
    11221 aatatatagt attaggttcg gttgcattgt ttaatgatag gaaaggttta gagcaagtaa
    11281 ttaaattact tgtgaaaaaa actgattatg catatgttat tataggtgat ggcccatcaa
    11341 aaaactatct aaagaaatta gcagaagaat gtgaagtatc aaatagagtt tttttcagcg
    11401 ggttcatgca caatggcaaa gactatatat atatgttgga ttgttatatg atgccgagtc
    11461 gggaggaagg gttcccatta gcattgactg aagcgataag tactaatgta gtcactgttt
    11521 gttctgatat tcctgttttt aaagagatac tggatgaggc ttcaacaagt tactttgctt
    11581 tagatgatat taattcatta tctctagctg tagaaagatc tattagtaat cgtgtagctc
    11641 tatcggcttc agcctataaa aaatactgtc tggagtatac gagagaaatc atggctaaga
    11701 agtatgttga attgtacatg cattagcgtg tgcctttatg gttttgattt aactctctaa
    11761 attatattta agtggtaaat atgaataaag tactcgtcac tggaggttct ggttttattg
    11821 gtactaatgt tgtcagtcgc ttacttgata tgaaatatca tgttttaaat attgacatca
    11881 aaccgcctat taaatctgaa catttatttt gttacaaata tattgatatg aaatctttta
    11941 gtcagctaag agaagcaata gctgactttg aacctaatat gattttacat ttggccgcta
    12001 gaactgattt gaatggaaaa aaattgtctg actatgagga taatattatt cctgtcgaaa
    12061 acttatgtaa aataattaca aattctcctt ttgttaatcg agtaatattt acgtctagta
    12121 tgcttgtttg tcgagctggg tatattcctg ctgatagtga agactattgt ccaacaactg
    12181 tttatggtga gagtaaagta gagactgaaa atattgttaa aaaatataaa aatttactgc
    12241 catcattttg tattgtcagg cctacgtcta tctgggggcc ttggtttaaa gagccatata
    12301 gagatttttt tgatatggtt ttagctggaa gattttttcg aattggtaag ccttcatgca
    12361 ctaaaaccta tggttatgtt ggtaatacgg taaatcaaat aatttcacta ttgtctttta
    12421 aagaagaaaa aagtaacgat aatgtttatt atttaggtga ctcgcctcca aataatatag
    12481 atgattggag tgtgaagatc tcagaacttg cagagaaaag aaaacctatc attttaccgt
    12541 tctttctatt aaaagtagct gcgcttattg gtgacttact cattagcgtt ggagtgaaat
    12601 tcccattatc cagttttcgt ttgaaaaata tgacaaccaa caatgtatta gactgtacga
    12661 aagtaatttc atgtaataaa tgggaaccca ttcctctaga gcatggcatc aaagctacac
    12721 ttaattggat gaaagaatac aaggtaatga aatgaaaaag gctctaatta ctggtattac
    12781 aggacaagat ggctcttatt tggccgagtt tttattagaa aagggttatg aggttcatgg
    12841 tattaagcgc cgagcttcat cttttaatac cagccgtatt gatcatattt atcaagatcg
    12901 ccatgagacg aatccacgct tctttttaca ttatggtgac ttgactgata cgtcgaattt
    12961 aattcgtttg gtccaggaaa ttcagcctga tgagatttat aatttgggtg cacaatctca
    13021 tgtggctgtt tcattcgaat caccggaata tactgccgat gttgatgcca tggggacact
    13081 gcgcttgcta gaggccattc gtatcaatgg gcttgaaaag aaaactcgtt tctatcaagc
    13141 ctcaacctca gagctttatg gtttagtgca ggaaacgcct cagcgtgaaa caacgccatt
    13201 ctatccgcgt tctccttatg ctgttgccaa aatgtatgct tactggatta cagtaaatta
    13261 ccgtgaatca tatggaatgt atgcttgtaa cggcatttta tttaatcatg agtctcctcg
    13321 tcgtggtgaa acatttgtta ctcggaagat tacccgtgct gttgcgaata ttgcattagg
    13381 tctagaaaaa tgtctctatt taggcaatat agattcgcta cgtgactggg gccatgcgaa
    13441 agattatgtg cgtatgcaat ggatgatgtt gcaacaagat aagccagaag attttgttat
    13501 tgcaacaggc aagcaaatta ccgttcgtga gtttgtgcgc atgtcagcaa gagaagcagg
    13561 gattgagctg gaatttagtg gggaaggcgt tgacgaagtt gccactgttg ttgctgttaa
    13621 tggtaaccat gtttcttctg tcaatattgg agatgtaata gtccgtgttg atccacgtta
    13681 tttccgtcct gctgaagttg aaacattatt aggcgatcca actaaggcta aaaaagtatt
    13741 aggctgggta cctgaaatta cggttgaaga aatgtgtgct gaaatggtcg ctagtgactt
    13801 agagcaggct aaacagcatg cattgttaaa agctaatggc tttgacgtat ccatttcgtc
    13861 ggagaattaa tacaaatgga taagaaacgc gtatttattg ccgggcatcg tggcatggtg
    13921 ggttctgcta ttgtacgtca acttaaaaac cgtaatgata ttgaattgat cattagggat
    13981 cgtactgaac ttgacctcat gtctcaatcc gatgtgcaaa aattttttgc tactgaaaaa
    14041 attaatgaaa tctatttggc tgcggcaaaa gtagggggga ttcaggccaa taataattat
    14101 ccggcagagt tcatctacga aaacttaatg atcgagtgca atattattca cgcggctcat
    14161 ttagctgaca ttcaaaaatt attatttttg gggtcttctt gtatttatcc aaaattggct
    14221 gcacaaccaa tgatagagga ggctctgtta actggcgtct tggaaccaac gaatgaacct
    14281 tatgccatcg ccaagatagc cggtatcaaa ctgtgcgaat cttataatcg tcaatatggt
    14341 cgtgattatc gcagtgttat gccaaccaac ctttatggtg aaaatgacaa ttttcacccc
    14401 gagaattctc atgtcattcc tgccttatta cgtcgcttcc atgaggctaa aattcgtaat
    14461 gataaggaaa tagttgtgtg gggaacgggt aaaccaatgc gtgagttcct acatgtagat
    14521 gatatggctg ctgccagtgt gcatgtcatg gagctgtctg atcaaattta tcaaaccaat
    14581 actcaaccaa tgctttcgca tattaatgtc ggaacgggtg tggattgcac tattcgtgaa
    14641 ttggcagaaa ctatggctaa agttgttggt tttaccggca atttagtttt tgattcaact
    14701 aagccggacg gaacaccacg aaagttgatg gacgtaagcc gcttggctaa actcgggtgg
    14761 tgttatcgga tttcgcttga ggtaggttta acgatgactt atcaatggtt cttggctcat
    14821 cagaataact tcagaaaata gtttgatttg ctatttggat atagcacttc ttaagttgat
    14881 taatgatttt ttaacttact aagtaaaaat atcattgggt ttctgtttgt tattcgttat
    14941 ctgatgatta tatttatttg catatcagct ctattttaaa aaataggaaa taattgctca
    15001 tgctattacc tgtaattatg gctggaggtg ctggtagccg tttgtggcca ttatcccgag
    15061 ctctttatcc taaacaattt ctagcgctaa cgtcagattt gacgatgcta caagaaaccc
    15121 tattgcgtct ggacggcctt ccccaccttg caccattagt gatttgcaac gaagaacatc
    15181 gctttattat cgcagaacag ttacgtcaga aaaatctggt gcatagcgga atactcttgg
    15241 aacctgttgg gcgcaatacc gcgccagcta tagcattggc tgccttacga gcaacaatga
    15301 gtggggatga tcctctatta ttggtattag cagcggatca cgtgattcag gataaacttg
    15361 catttattcg tgccgtccaa cttgctgaac cgcttgctga agcgggaaaa ttggttactt
    15421 ttggaatcgt gccaaagagt ccggaaacag gatatggata tattcgccaa gggaagcaag
    15481 tcgtagatgg agcttatcag gttgctgctt ttgttgagaa gccagacctg attactgcag
    15541 aacggtattt ggcttcgggt gactattatt ggaatagcgg tatgtttgta tttaaagcat
    15601 ctcgctatct acaggaatta gatctacatc gaccggatat tttggctgct tgcaagcaag
    15661 ccattgccgg tcaacatact gatttagatt ttattcgtct caatgaagaa gctttctcta
    15721 gttgccctgg tgaatctatc gactatgctg tgatggaaaa aactagcgat gccgttgtcg
    15781 taccaatgga tgctcagtgg agtgatgttg ggtgctggtc agcgctttgg gacattaata
    15841 ctaaagatgg tcatggaaat gttattcgtg gcgatgtatt aatggaagat actaataata
    15901 gctacgttta ttctcaaaat aggctcattg caactgtagg cattaatgat ttggtcattg
    15961 ttgaaactaa agatgccatt ttagttgctc ataaagataa agttcaagat gttaaaggga
    16021 tagttggaca acttaagctt gaatctcgat gtgaatatct acagcaccgg gaagtctatc
    16081 gcccttgggg ggcgcatgat gctatagcta aaggtgttcg ctatcatgtc cagcatgtaa
    16141 cggtgaaacc aggtcaacgt attgctactc aaattcatta tcacagagca gaacattggg
    16201 ttgtagtttc tggtattgcc aaagtacatt atggaaaaga aacttatttg gttaatgaga
    16261 atgaatccac ttatattccc gtcggtattg ctcattctat tgaaaatcca ggtcagatcc
    16321 ctctggaaat aatagaggtt catactggta attacatttc agaagatgac gtagaacgaa
    16381 tcgatgattt aggtgtaggg tattaattat gaagataagt attattactg ctacatataa
    16441 tagcgagaga acaatttcgg ataccctatc ttctttggaa aaacaaacct atctggatgt
    16501 tgagtatatt attgttgatg gtgcatcaaa ggataataca ttaactgtta tcagtcagaa
    16561 ttctacgcga gtcactaaga ttattagtga gtctgatcaa ggtatttatg atgctttgaa
    16621 taaagggata gatttggcaa caggtgacat tattggtttt ttacattctg atgatttact
    16681 tgcctatcca ggggccctat ctgatattgt agaaaccttt gaaaaacagc aatgtgatgc
    16741 tgtatatggt gacttacagt atgtcgcaaa aaatgattta aataaggtaa tcagatgttg
    16801 gaaaagtgtt ttttttaacc atgaaaaaat gaagtatggt tggatgcctc cccatcctac
    16861 tttttatatg aaacgagatc tttatataag gtttggaggt tttgacttga gttataaaat
    16921 atcagccgac tatgattctc ttacgcgtta tatcattaat tataaaatta aagttgctta
    16981 tttacctaag gtaattatta aaatgagagt tgggggaata agtaatcggt cattgggaag
    17041 tatgttgtta aaatctaaag aagatataca aataatgaag ctccgtgggc tattctggcc
    17101 tatgtcattt ttatgcaaaa acttatctaa acttcctcag tttataaagt gatcttatgc
    17161 caaaactaac ctgttttaaa gcctatgata ttcgtggccg gttgggcgat gaattgaatg
    17221 aagatatagc ttaccgtatt ggtcgcgcgt atggtgagtt tgctaaacct aaaaaggttg
    17281 tagtaggggg ggatgttcga ttaaccagtg aaagccttaa gctagcgtta agtcaaggtt
    17341 tacaagacgc gggtactgat gtattagata ttggtttgtc aggtactgag gagatatatt
    17401 tttccacctt ccatcttggg gttgatggtg gtatagaagt gactgccagc cataacccaa
    17461 tagactacaa tggaatgaag ttagtttgtg aaggctccag gcctatcagt ggagatacag
    17521 ggttacggga tattcagtat ttagctgaac agaatgaatt ccctccagtg gacagtgaaa
    17581 aaagaggagg ttataaaaaa tatctattat taatgactat gttgaacact taattagcta
    17641 tattaaccct tctcttttta agccgttgaa attagttgta aatactggca atggtgctgc
    17701 tggtcatgtt attgatgctt tggaaaagcg tttttcagaa ttaaacatac cgataagtct
    17761 gattaaaatt catcatgagc cagatggtac attcccgaat ggtattccga atccactgtt
    17821 accagaatgc cgccaggata ctactgatac tgtgttgatg catgacgctg atatgggtat
    17881 tgcctttgat ggcgattttg accgttgttt cttctttaat agtaagggtg agtttattga
    17941 aggctattat atcgtggggc ttttagccga agcttttctt caaaaaaatg ctggagctaa
    18001 aattatccat gatccacgtt taagctggaa tactattgat atagttaatt cttctggtgg
    18061 aacgcctata atgtccaaaa ccgggcacgc ttttattaaa gaacggatgc gagaagaaga
    18121 tgcggtttat ggtggtgaaa tgagtgctca tcactacttc cgtgactttg tttattgtga
    18181 ttcagggatg attccatggt tactgattgc tgagctttta tgtgtcaaag aaaaaagttt
    18241 ggagcagtta gttgaagaac ggatgcgtat ttaccctgca tctggagaaa ttaattctaa
    18301 gctaaacgat ccaatctctg cgatagcgcg tgtccgtgct gaatatgaag ttacggctat
    18361 agctattgac gaaactgatg gtattagtat ggaatttgat gggtggcgtt ttaatttacg
    18421 cagttcaaat actgaacctg ttgttcgtct caatgtggag tcgcattaca ataaaacatt
    18481 aatgcggtat aaaacagcgg agatactttc tctcttgaga caagagtaat gaatttagaa
    18541 agcatttcta ttattgctat gaatacaggt aatactcaat gagtaataaa cagacacaaa
    18601 gtaaccttga taatccaata ccaaataact atgatttttc aaatatatct tcttcaaaaa
    18661 atgaaattga tctttttgaa ctgtttggta ttatttttag ctccaaactt aaaataatat
    18721 ttattacatt tgtttttata atcatcggat taggtatttc atatatcctc ccccaaaaat
    18781 ggacaagtac tgcaataata gctcttcctg gtgatgagca agttcaagtt ctggatgaac
    18841 tcgtcacaaa tctaaccgta cttgatataa aggttgatgt gagtgctaat tatttgctgt
    18901 caacattcaa gcaaaatttt gattctcaag atcttcgtga acaatattta gtgaatacta
    18961 attattttaa acgtttgctg aaagacaatc cagaagacgg tttagataaa cgagcgttaa
    19021 tagaacgaat agtgaatgaa aatatttctt cggttaaccc agtgaaagat aaaactgagg
    19081 gtgacaatga atatcgctat tataaattat catatagtgc aagcacaccg acagatgctc
    19141 gtgacttgtt gcaaggttct attaactata taaataccat cgttaatgct gatgttttcc
    19201 gaaaaataca gcgtgcggtg gatttagcta agggtatcgg tacagataaa tactctatgg
    19261 aactgttgaa agctagaaat aatcaaaaag ttaaaattga gcgtttaagg tatgcttcct
    19321 ctatcgctga tgccgcaggc gtaaaaaagc cagtttacag tagtggctca gccattagtg
    19381 atgatcctga cttccctatt accatgggat ccgatgcgct gaaccgtaaa ctggaaatag
    19441 agaagtcagt taccgatctg gcttcaatca atgctgaact tctaaaccgt aagttgtatt
    19501 tggataaatt aaataggtta gaaattccta atgttaatat cgtgccattt aaatatttgc
    19561 aacagccaac ggaacctact aaaagagatg cacctaagcg cgcattgatt gtgattctgt
    19621 ttgcactggt aggtcttatg ggctctgtcg gttttgtttt agttgagcac tttgtgcgtg
    19681 ggcggaagcg agaagaagag gggcttaagc tctctcaaac taaggaatag gttttaaacg
    19741 aatttatcta acggctgggt gaggtttctc atctggccgt tctattttat cgccctgtat
    19801 tattttacta ttttactatt ttactatttt actatttttc cgtttttaag ttagccgcta
    19861 ctgcccgatt gtaactaatt cccctgcatt atgcgtccca gcaaccctta tgctaaaatt
    19921 cgttatcttt tcatcgctaa atttttaact caaaacaatg aaatttcctg gtaagcgcaa
    19981 gtccaaacac tactttccag tcaatgcccg cgatccacta ttacaatcgg tgcaggctga
    20041 aaatgaagtg agtacctctt atatcgtggt atgacagttc ct
//
