LOCUS       AF461768               20511 bp    DNA     linear   BCT 26-SEP-2002
DEFINITION  Yersinia pseudotuberculosis serogroup IA O-antigen gene cluster,
            complete sequence.
ACCESSION   AF461768 U29692
VERSION     AF461768.1
KEYWORDS    .
SOURCE      Yersinia pseudotuberculosis
  ORGANISM  Yersinia pseudotuberculosis
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Yersinia.
REFERENCE   1  (bases 1 to 20511)
  AUTHORS   Hobbs,M. and Reeves,P.R.
  TITLE     Genetic organisation and evolution of Yersinia pseudotuberculosis
            3,6-dideoxyhexose biosynthetic genes
  JOURNAL   Biochim. Biophys. Acta 1245 (3), 273-277 (1995)
   PUBMED   8541300
REFERENCE   2  (bases 1 to 20511)
  AUTHORS   Reeves,P.R., Hobbs,M., Valvano,M.A., Skurnik,M., Whitfield,C.,
            Coplin,D., Kido,N., Klena,J., Maskell,D., Raetz,C.R. and Rick,P.D.
  TITLE     Bacterial polysaccharide synthesis and gene nomenclature
  JOURNAL   Trends Microbiol. 4 (12), 495-503 (1996)
   PUBMED   9004408
REFERENCE   3  (bases 1 to 20511)
  AUTHORS   Pacinelli,E., Wang,L. and Reeves,P.R.
  TITLE     Relationship of Yersinia pseudotuberculosis O antigens IA, IIA, and
            IVB: the IIA gene cluster was derived from that of IVB
  JOURNAL   Infect. Immun. 70 (6), 3271-3276 (2002)
   PUBMED   12011023
REFERENCE   4  (bases 1 to 20511)
  AUTHORS   Hobbs,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-1995) Department of Microbiology, University of
            Sydney, Building G08, Sydney, NSW 2006, Australia
REFERENCE   5  (bases 1 to 20511)
  AUTHORS   Pacinelli,E., Wang,L. and Reeves,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2001) Microbiology, University of Sydney, Sydney,
            NSW 2006, Australia
  REMARK    Nucleotide and amino acid sequences updated by submitter
COMMENT     On Sep 26, 2002 this sequence version replaced U29692.1.
FEATURES             Location/Qualifiers
     source          1..20511
                     /organism="Yersinia pseudotuberculosis"
                     /mol_type="genomic DNA"
                     /isolate="M444"
                     /db_xref="taxon:633"
                     /note="serogroup: IA"
     gene            207..1196
                     /gene="ddhD"
     CDS             207..1196
                     /gene="ddhD"
                     /note="DdhD"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-6-deoxy-delta-3,4-glucoseen reductase"
                     /protein_id="AAN23035.1"
                     /translation="MSLNVKLHPSGIIFTSDGTSTILDAALDSNIHIEYSCKDGTCGS
                     CKAILISGEVDSAENTFLTEEDVAKGAILTCCSKAKSDIELDVNYYPELSHIQKKTYP
                     CKLDSIEFVGEDIAILSLRLPPTAKIQYLAGQYIDLIINGQRRSYSIANAPGGNGNIE
                     LHVRKVVNGVFSNIIFNELKLQQLLRIEGPQGTFFVREDNLPIVFLAGGTGFAPVKSM
                     VEALINKNDQRQVHIYWGMPAGHNFYSDIANEWAIKHPNIHYVPVVSGDDSTWTGATG
                     FVHQAVLEDIPDLSLFTVYACGSLAMITAARNDFINHGLAENKFFSDAFVPSK"
     gene            1222..2007
                     /gene="ddhA"
     CDS             1222..2007
                     /gene="ddhA"
                     /note="DdhA"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-P-cytidylyltransferase"
                     /protein_id="AAN23036.1"
                     /translation="MEIQVKAVILAGGLGTRLSEETVVKPKPMVEIGGKPILWHIMKL
                     YSSYGINDFVICCGYKGYVIKEYFANYFMHMSDITFCMRDNEMIVHQKRVEPWNVTLV
                     DTGEDSMTGGRLRRVKDYVKDDEAFCFTYGDGVSDVNIAELIEFHKSHGKQATLTATY
                     PPGRFGALDIKDKQVRSFKEKPKGDGALINGGYFVLSPKVIDLIDGDKSTWEQEPLMT
                     LAAQGELMAFEHAGFWQPMDTLRDKIYLHELWEEGRAPWKVWE"
     gene            1910..3085
                     /gene="ddhB"
     CDS             1910..3085
                     /gene="ddhB"
                     /note="DdhB"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose-4,6-dehydratase"
                     /protein_id="AAN23037.1"
                     /translation="MPVSGSQWIRCVTRSICMNYGKKAGHLGRYGNNKMINNSFWQGK
                     RVFVTGHTGFKGGWLSLWLQTMGAKVKGYSLTPPTVPSLFETARVADGMQSEIGDIRD
                     QNKLLESIREFQPEIVFHMAAQPLVRLSYSEPVETYSTNVMGTVYLLEAIRHVGGVKA
                     VVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYRNSFFNPANYGQH
                     GTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPVIIRNPHAIRPWQHVLEPLSGY
                     LLLAQKLYTDGAEYAEGWNFGPNDADATPVKNIVEQMVKYWGEGASWQLDGNAHPHEA
                     HYLKLDCSKAKMQLGWHPRWNLNTTLEYIVGWHKNWLSGTDMHEYSITEINNYMNTK"
     gene            3103..4416
                     /gene="ddhC"
     CDS             3103..4416
                     /gene="ddhC"
                     /note="DdhC; formerly known as rfbH"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-4-keto-6-deoxy-D-glucose-3-dehydrase"
                     /protein_id="AAN23050.1"
                     /translation="MSQEELRQQIAELVAQYAETAMAPKPFEAGKSVVPPSGKVIGTK
                     ELQLMVEASLDGWLTTGRFNDAFEKKLGEYLGVPYVLTTTSGSSANLLALTALTSPKL
                     GVRALKPGDEVITVAAGFPTTVNPTIQNGLIPVFVDVDIPTYNVNASLIEAAVSDKTK
                     AIMIAHTLGNLFDLAEVRRVADKYNLWLIEDCCDALGSTYDGKMAGTFGDIGTVSFYP
                     AHHITMGEGGAVFTQSAELKSIIESFRDWGRDCYCAPGCDNTCKKRFGQQLGSLPFGY
                     DHKYTYSHLGYNLKITDMQAACGLAQLERIEEFVEKRKANFKYLKDALQSCADFLELP
                     EATENSDPSWFGFPITLKEDSGVSRIDLVKFLDEAKVGTRLLFAGNLTRQPYFHDVKY
                     RVVGELTNTDRIMNQTFWIGIYPGLTHDHLDYVVSKFEEFFGLNF"
     repeat_region   4427..4442
                     /rpt_type=inverted
     gene            4453..5310
                     /gene="prt"
     CDS             4453..5310
                     /gene="prt"
                     /note="Prt; formerly known as rfbS"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-paratose synthetase"
                     /protein_id="AAB48322.1"
                     /translation="MKILITGVSGYLGSQLANALMLEHEVAGTVRAGSVCNRITDIGN
                     VNLINVTDSGWIDKVLSFSPDVVINTVALYGRKGELLSELVDANIQFPLRILEMLVST
                     GKGLFFQCGTSLPADVSQYALTKNQFTELAREYCNKFSGKFIELKLEHFFGPFDDSTK
                     FTTYVINSCRSHSDLKLTAGLQRRDFIYINDLINAFKIMISKSESLISGESISIGSGH
                     AVTIKEFVETVAKMTSYQGNLQFGAIPTRENELMYSCASLARIQELGWLCQYSLNSAI
                     KDTLNRMRV"
     gene            5311..6594
                     /gene="wbyH"
     CDS             5311..6594
                     /gene="wbyH"
                     /codon_start=1
                     /transl_table=11
                     /product="WbyH"
                     /protein_id="AAN23051.1"
                     /translation="MDMKFCKNRYINTVILGAGVAGLGAALKAREVNIEYEIFEAKTS
                     AGGLLDNFVIDGYRFDNAVHLSFATEEKVRDVFDRTPYFSHSPDAVNFETDKWLKHPV
                     QNNLYPLPAIEKVTLIESLIHRPESELADNYESWLIHQYGNEIAKRYPMRYTRKYWQC
                     NANELSVSWIGNRLRRAKLSEILYGAFTDDTPNDYYAKEMRYPKKGGFKSFIQPLIDE
                     SIINYNYEVTEIDLSGKTIKFSNGVIISYENLINTLPLPLFIEFCGANVPTSVKKSAS
                     KLGATSLDLISVGFNKSIIKDLWFYIYDEDIYASRAYSPSVKSSDNVPDGCSSLQFEI
                     YNPGRDSQYTVQELKDNVIYAMKKMGVANNEDIVFLHHKRLPWGNVVFKKDMEKYRDI
                     VREYIFDNQVKSVGRFGEWDYLWSNQSFLSGYSSI"
     gene            6776..8119
                     /gene="wzx"
     CDS             6776..8119
                     /gene="wzx"
                     /note="Wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AAN23038.1"
                     /translation="MRINYQMVWGLLNQGCNIFIPFVIMFMSYKYLPLEMASVWVIFL
                     SMISLITLFDFGLSPAIVRNVSYVISGAQNLVKRGIDDIIIKDVISYPLLSRLLFDIK
                     RIYLYLSLIAFFIIVIGGLWYFYYISPLDIKIEVAYSWVLFSSALIINLIYLYYVPVL
                     TGLGEIENSYKANVFGRIIWFFLSLLVFIFSPSILLLSLSFVFSVFINRYLCYFFYIR
                     NSHVKAIDKTEMDKKSTVPFIGHNAAKLGVVSLGSFLINRSTTLIVGIVCPIVTAGQF
                     VLSMQVFFALMAISNILLSIKIPEISQAVAKREHYTVKILIYKVVAFSSSIYLLGFVT
                     FLILAEYVLPTIGVSLSFLPLDYLLILGLIYFLEMNHSICATIITSKNNVPFVFASLF
                     SGGLIILLSIILSVHFKYGVVGLILAQGIVQLMYNNWKWPLMVYSEFIKNNIEDR"
     gene            8130..9122
                     /gene="wbyM"
     CDS             8130..9122
                     /gene="wbyM"
                     /note="WbyM"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAN23039.1"
                     /translation="MKSNIIIDNSNSDDVLLTIAIPTYKRFGLLKETLKSVFSLEFNI
                     PVEVIVVDNDPEHPELVLSEMAEFERYDFIYYKNIENYGMFGNWNQCLNLGRGKLITI
                     LHDDDLLCANFPRELDRFLKEYSCHDDIPLIGFGHYLLDQRKSEDKVNKNILYKISKK
                     IFNAFRKYIIKPKVVSITLDEIFWGNIFCGTLGVVMDRNKALSISGFDEKNYPVSDYD
                     FWIRWIQKYGPIKYNKTKVSYYRILDNESMRPDVISNFIKKTYELRLMMIKETPLLVN
                     QESNAINLKKLDEYSFNVNWSREGDFNLGILDTVNYIYIKIKCISCKYFSFWLH"
     gene            10136..11245
                     /gene="wbyB"
     CDS             10136..11245
                     /gene="wbyB"
                     /note="WbyB"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAN23040.1"
                     /translation="MNILIVYLGRKGGGAHYTYELVNELSKKTNVSLLVSKQAENIKS
                     YESLNISLNTINTFNGMFSFILSSFKLPFIKNKIKKIILDEKIDIVISTMTHVWNGFI
                     FTPNFMMKIPYILTIHDAVPHSGEGNFILNLLNNKDIKNANAYIALTEHVKNQFINIY
                     GDKKDICILPLGSFNFKSGEIKSWCGVRPLRILFFGRIHEYKGIDLLLDSMIILQEKY
                     DLELSIYGQGDLSDYVDKIDVIKKINIENRWIGDSEVGDILQAHDVCVIPYKDASQSG
                     VIPVAQSAGLPTIVNPVDGLIEQIEKDKTSLVTDRVDSVSLALSIEKIIKNPELVNKL
                     SIGSLEYASRKLSWVPIVNKLITYSKETLNSSDRS"
     gene            11325..12410
                     /gene="wzy"
     CDS             11325..12410
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AAN23041.1"
                     /translation="MLYKKEFILLILVKVLFSFFAFFIYSNFSQLGDSNRYLNATLNF
                     NNILDRTQFVDNTFAFLKYVMSSSLLVNISISVLFGYSFFYVFKDVLIFVDKKLLYMS
                     FLLPSFQIWTSVAGKEIIAVIGFLFFIKWVINIQFGRDNRIHYLVIGILFGVFLRPHY
                     GIAYIYLAISAIILSRIKFRVFSNGFYVLSLFIIAIMLFLVLALTVNIWSAQFLSVLD
                     TIEGYFLSYDASNSNRYDIEWGTISDYFYNITWGFFISIIGPTLNETLNRVVYLPFFI
                     EGILSFILMIVISYRLYKSTNENVLYRKLFYFSFLPALIIILMIHYPFGLFNPGSAIR
                     YKQNITPLIYFYPLLMLACINKYKVKG"
     gene            12598..13740
                     /gene="wbyC"
     CDS             12598..13740
                     /gene="wbyC"
                     /note="WbyC"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAN23042.1"
                     /translation="MKLKKILLCGNSSWSMYNFRLGVIKFLISNQYSVVILAPRDDYS
                     DKLISIGCKFIDINLSAQGVNPFNELKFLFSLVSIYREEKPDFIINYTIKPNIYGSLA
                     SKVTNIPSIAITTGLGFVFTRKSIVSFFAKLLYKIALSCCQEVWFLNSDDQDVFLRKN
                     IVNKNKTKILYSEGIDVTHFSPRKRNDHHDEDTFCFLLVARMLRDKGVPEFVSAARII
                     KKKYPNVSFRLLGFCDVENPSAITRSEIDSWVNEGVVEYLGVTDDVRQYIADSQCIVL
                     PSSYREGIPRILMEAASMAKPVITTNNVGCREVILDEVTGYLCEVNNVDSLVSACEKL
                     LSLDEAQIIDMGKKGRKLVEEKFSEEKIISQYSECINYYLIEKSIK"
     gene            13965..14798
                     /gene="dmhB"
     CDS             13965..14798
                     /gene="dmhB"
                     /note="DmhB"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23043.1"
                     /translation="MTKVFILGSNGYIGNNLMESLCDNIEVITVGRSNADIYINLESD
                     DFQSLLNKVEFKDTVIFLSAISSPDECNNNYDYSYKINVKNTISLISLLLAKNVRVMF
                     SSSDAVFGATQNLCDENSEKKPFGKYGEMKSEVEDYFTLEDDFFVVRFSYVLGRNDKF
                     SMMIKEFYEQGKILDVFDGFERNVISINDVTAGIKNIICDWDSIKTRIVNFSGNELVS
                     RQDIVNALVKEKYLNLKYKFTAAPESFWVGRPKKIHTKSNYLESILNRKLESYLEVIK
                     E"
     gene            14801..15829
                     /gene="dmhA"
     CDS             14801..15829
                     /gene="dmhA"
                     /note="DmhA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23044.1"
                     /translation="MNNVLITGFTGQVGSQLADYILENTDDHVIGMMRWQESMDNIYH
                     LTDRINKKDRISIQYADLNDLMSLYNLIDTVRPKFIFHLAAQSFPRTSFDIPIETLQT
                     NIIGTANLLECIRKLKQQDGYDPVVHVCSSSEVYGRAKVGEALNEDTQFHGASPYSIS
                     KIGTDYLGQFYGEAYGIRTFVTRMGTHTGPRRSDVFFESTVAKQIALIEAGHQEPKLK
                     VGNLASVRTFQDARDAVRAYYLLALESGKGNIPNGEVFNIAGDEAFKLPEVIELLLSF
                     STRNDIEVVTDTDRLRPIDADYQMFDSTKIKSYINWKPEIKAADMFRDLLQHWRNEIA
                     SGRIPLNR"
     gene            15847..16875
                     /gene="hddA"
     CDS             15847..16875
                     /gene="hddA"
                     /note="HddA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23045.1"
                     /translation="MKIRSKAPLRLGIAGGGTDVSPYSDTFGGCVLNATINMYAYAYI
                     DDELDENKVIFEAADLGLREEINLDKEINIEGQLKLHRAVYLRVMKDYFGGELKPIRI
                     ITHSDAPAGSGLGSSSTVVVSMLEGLRQMYSLPLGEYDLAQLAFKIERVDCGLSGGKQ
                     DQYAATFGGFNFMEFYKCNRVIVNPLRIRRYIINELESSLILYFTGASRDSAKIINEQ
                     IKSLEEKKGSKLEAMHRVKESAYKIKEYLLKSDIDAMSSTFLDAWRSKKETSSSITNP
                     MIEEIEMEIFNIGAKSMKVSGAGGGGFMMIFVEPEKKHIVENKLKAFGGEVYKFQFVE
                     EGAYSWTI"
     gene            16863..17453
                     /gene="gmhA"
     CDS             16863..17453
                     /gene="gmhA"
                     /note="GmhA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23046.1"
                     /translation="MDNLNYIQKYLENSISVKRTLQESKEVLEQVSLVTDLIIEAYRN
                     GNKVILAGNGGSAADSQHIAAEFVSRFFFDRPGLPAMALTTDTSMLTAIGNDYGFDKL
                     FSRQLQAQSRPGDVFIGISTSGNSENIINAMKLTKELGVTSVALCGESGKLKEIVDYS
                     INVPSKITPYIQECHICIGHMICAIVEKVIFGSEDN"
     gene            17455..18132
                     /gene="hddC"
     CDS             17455..18132
                     /gene="hddC"
                     /note="HddC"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23047.1"
                     /translation="MYDVVILAGGLGTRLKSVSGDIPKPMVDISGKPFLYRLMEYLED
                     QGVQRIILSLSYKADYIIDSVIKDNPVNSKVDFIIENEPLGTGGAIKNACKYIEASKF
                     IVINGDTYCELDYKKFIESSLDSDLQISGVEVDDVCRYGSLDIDHDFHVNSIVEKGRQ
                     GTGIINSGTYILSKKIIEDYPHDKFSFELDFLPKFTGVFKAFVTKAYFIDIGIPEDYY
                     KACEKFK"
     gene            18129..18659
                     /gene="gmhB"
     CDS             18129..18659
                     /gene="gmhB"
                     /note="GmhB"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23048.1"
                     /translation="MKIAFLDRDGVINKEVNYLYKIDDFVFTPNCIDGLRRLREKNFE
                     IVIITNQAGIAKGFYSVDDYNDLTFWYREKLLSYGVDILDILYCPHHPNGCVPEYSIE
                     CNCRKPKTGLLEEVAKKYQIDIKESILVGDKQSDLNAGISFGISKVYLVETGHKIPKE
                     NYKKYHVYSDLSCIPL"
     gene            19134..20285
                     /gene="wzz"
     CDS             19134..20285
                     /gene="wzz"
                     /note="Wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant-like protein"
                     /protein_id="AAN23049.1"
                     /translation="MSNKQARSNLDSPIPNNYDFSNVSSSRNEIDLFEIFGVVFKSKF
                     KIILITLFFLISGLVVSYILPQKWTSTAIIALPGDEQVQVLDELITNLTVLDIKVDVS
                     ANYLLSTFKQNFDSQDLREQYLVNTNYFKRLMKNNPEDGLDKRALIERIVNENISSVN
                     PLKDKTEGENEYRYYKLSYSASTPTDARDLLQGSINYVNTIVNADVFRKIQRAVDLAK
                     GIGTDKYSMELLKARNNQKVKIERLRYASSIADAAGVKKPVYSNGSAISDDPDFPITM
                     GSDALNRKLEIEKSVIDLASINTELLNRKLYLDKLNRLEIPNVNIVPFKYLQQPTEPT
                     KRDAPKRALIVILFALVGLMGSVGFVLVEHFVRERKREEEGLKLSQTKE"
BASE COUNT     6584 a   2987 c   4027 g   6913 t
ORIGIN
        1 ggggatagaa cccaatagtt gccttttact ctggaaccgg caggaagaag accttctaca
       61 attttttact ttagtgattt ttaaccgtac ttctttatca aaaattattt gcttttttgt
      121 ttctatttta gtcactgaat ttttttgact taagtttgta ttgagtacgt ctaataaacc
      181 ttacataata tatttggact tattttatgt cattaaatgt taagctgcat ccatcaggta
      241 ttatttttac ttccgatgga acatctacaa tattagatgc ggctctggat agtaatatac
      301 atattgaata cagctgcaaa gatggaacct gtggttcttg taaggcaata ttgatttctg
      361 gtgaagtaga cagtgcggaa aatacctttt taactgagga agatgttgct aaaggtgcaa
      421 tcctcacttg ttgctctaag gctaaatctg atattgagtt agatgttaat tattatccag
      481 agttaagtca tatacaaaaa aaaacttacc catgtaaatt agatagcatt gaatttgttg
      541 gtgaagatat tgccattctc tccttacgct tgccaccaac ggccaaaata cagtatctag
      601 cgggccaata cattgattta attattaatg gacagcgtcg tagttactct attgctaatg
      661 ctccaggtgg taatggcaat atcgaattac acgtacgtaa agtcgttaat ggtgtattca
      721 gcaacatcat ttttaatgag ttaaaattac agcaactttt acgaattgaa ggtcctcaag
      781 ggaccttttt cgttcgtgaa gataatctcc ctattgtttt tcttgctggt ggaacaggtt
      841 ttgcaccagt gaaatcaatg gttgaggcgt tgatcaataa aaatgaccaa cggcaggttc
      901 atatctattg gggaatgcca gcagggcata atttctattc tgacattgcc aatgagtggg
      961 ctataaaaca ccctaacatt cattatgtgc ctgttgtatc aggcgatgat agtacttgga
     1021 ccggagccac tggttttgta catcaagcgg tgcttgaaga tatacccgat ctcagcttat
     1081 ttactgttta tgcctgtggt tcattagcga tgattactgc tgctcgtaat gatttcatca
     1141 atcatggatt agctgaaaat aaatttttct ctgatgcctt tgtgccatca aaataacttt
     1201 gagagatcaa agtaatacgt aatggagatt caagtgaaag cagtcatttt ggccggaggc
     1261 cttggaaccc gtcttagtga agagaccgta gtaaaaccaa aaccaatggt agagattggt
     1321 gggaagccta ttctctggca tattatgaaa ctttactctt cttatggcat caatgatttc
     1381 gttatttgct gtggttataa aggctatgtc attaaagaat attttgcgaa ttactttatg
     1441 cacatgtcgg atattacctt ctgcatgcgt gataatgaaa tgatagtaca ccaaaagcga
     1501 gtcgaaccct ggaatgtcac gttagtagac accggcgaag attctatgac cggtggccga
     1561 ctgaggcgtg taaaagatta cgtcaaagac gatgaggctt tctgtttcac ctatggtgat
     1621 ggtgtgagtg acgtcaatat tgctgaatta attgaattcc ataagagcca cggcaagcaa
     1681 gccacattaa cggcaaccta tcccccaggc cgttttggtg cgctggatat taaagataaa
     1741 caagtacgta gttttaaaga aaaaccaaaa ggcgatggcg cattgatcaa cggcggttat
     1801 tttgttttgt cgcctaaagt tatcgatctg atcgatggtg ataagtctac ttgggagcag
     1861 gaacctttaa tgacattagc tgcgcagggg gagttgatgg cgtttgaaca tgccggtttc
     1921 tggcagccaa tggatacgtt gcgtgacaag atctatctgc atgaactatg ggaagaaggc
     1981 agggcacctt ggaaggtatg ggaataacaa aatgattaat aatagtttct ggcaaggtaa
     2041 acgggttttt gtaacaggcc atactgggtt taaaggtggc tggttgagtt tatggttgca
     2101 aaccatgggg gcaaaggtaa aaggttactc tctgaccccc cccacggtgc ctagcctatt
     2161 tgagaccgca cgagttgccg acgggatgca atcggaaatc ggtgatattc gtgatcaaaa
     2221 caaattatta gaatcaatcc gcgaattcca accagaaatt gttttccaca tggctgctca
     2281 gccactggtc cgtctatcct attccgagcc tgttgaaacc tactcgacga atgttatggg
     2341 tactgtttat ttgctggagg ctattcgcca tgttggtggc gtcaaagcgg tggtcaatat
     2401 caccagtgat aaatgctacg acaataaaga gtggatctgg ggctatcgtg aaaatgaagc
     2461 gatggggggg tatgatcctt actccaacag taaaggttgt gcggaattag tgacgtcatc
     2521 ctaccgtaat tcgttcttca atccagcgaa ctatggccag catggcactg ccgtagcgac
     2581 agtgcgtgcg ggtaatgtca tcggtggtgg cgattgggca ttggatcgca tcgttccaga
     2641 tattcttcgg gcgtttgaac agtcccaacc agtgattatt cgcaacccac atgccattcg
     2701 cccatggcag catgtgttgg agcctttgtc gggttatttg ctgttggcac agaagttata
     2761 tactgacggt gctgaatatg ccgaaggttg gaactttggt cctaacgatg ctgatgctac
     2821 tccagtaaaa aacattgttg aacaaatggt gaaatattgg ggagagggtg caagctggca
     2881 attagatggc aatgctcacc ctcatgaagc tcattatctg aaactggatt gttcaaaagc
     2941 taaaatgcaa cttggctggc atcctcgctg gaacttgaat actacgctcg aatatattgt
     3001 gggctggcac aagaactggt tatcaggcac agatatgcat gaatacagta ttactgaaat
     3061 taataattac atgaacacta aatgatttga ggtcatagat aaatgagtca agaagaatta
     3121 cgtcaacaga ttgctgagct ggttgctcag tacgctgaaa cggctatggc ccctaagcca
     3181 tttgaagcag gtaagagtgt cgttccacct tcaggtaaag ttattggtac caaagaactc
     3241 cagttaatgg ttgaagcttc tttagacggt tggctaacaa cgggccgttt taatgacgct
     3301 tttgagaaaa aactaggcga gtatttgggc gttccttatg ttctgactac aacttctggc
     3361 tcttcagcca acttattggc tttgaccgcg ctgacctcac ctaaattagg ggtacgggcg
     3421 ttgaagccag gtgacgaagt tattactgtt gccgcaggtt ttccaaccac agtaaaccca
     3481 actattcaga atgggttaat tcctgtcttt gttgatgttg atattccaac ttacaatgta
     3541 aatgctagcc tgattgaagc ggcggttagt gataaaacca aagctattat gattgcccac
     3601 acattaggta atctattcga tctagctgaa gttcgccgag tagctgataa atataacctg
     3661 tggttaattg aagactgctg cgatgcgttg ggttccacct acgatggaaa aatggctggt
     3721 acatttggcg atattggtac cgttagcttc tatcccgctc atcatatcac catgggtgaa
     3781 ggtggggcgg tatttacaca atcggcggaa ctgaagagta tcatcgaatc tttccgtgat
     3841 tggggtcgtg attgttattg tgctccaggc tgtgacaaca catgtaaaaa gcgtttcggc
     3901 cagcaacttg gctctttacc attcggttat gatcataaat atacttattc ccatttaggc
     3961 tataacctaa aaatcacaga tatgcaggct gcctgtggtt tggcgcaact agagcgcata
     4021 gaagagtttg ttgaaaaacg taaagctaac tttaaatacc ttaaagacgc actccaatct
     4081 tgcgctgact ttcttgagtt accagaagcg actgaaaatt cagatccatc atggtttggt
     4141 tttcctatca ctctgaaaga agatagcgga gttagccgca ttgatctggt taaattcctt
     4201 gatgaagcta aagtgggaac tcgcctacta tttgccggta atttaactcg ccagccgtat
     4261 ttccatgatg tgaaataccg tgttgttggt gaattgacaa acaccgatag aattatgaat
     4321 caaactttct ggattggtat ttacccaggc ctgacacatg atcatttgga ttatgtcgtg
     4381 agtaagtttg aagagttctt tggtttgaat ttttaacagg agcaaggagg caacactgcc
     4441 tctttttttt atatgaaaat tcttattacc ggcgttagcg gttatttggg gagccaatta
     4501 gccaatgctt taatgctaga gcatgaagtt gcgggaactg tgcgtgctgg ttctgtatgt
     4561 aatcgcatca ctgatattgg taatgttaat ttaattaatg ttactgacag tggctggata
     4621 gataaggttt tgtcattttc tcctgatgtg gttattaata ctgtagcatt atatggaagg
     4681 aaaggagagt tactttcaga gctggttgat gccaatattc aatttccatt acgtatatta
     4741 gaaatgttag tttcaacagg aaaaggcttg ttttttcagt gcggaacatc tctacctgcg
     4801 gatgttagtc aatacgcttt aactaaaaat caattcactg agcttgccag agaatattgc
     4861 aataaattta gtggtaaatt tatagagtta aaattagaac atttttttgg tccttttgat
     4921 gattcaacta aatttacaac ttatgtaatc aatagttgta gaagtcatag tgacctaaaa
     4981 ttgacagccg gcttacaacg ccgtgatttt atttatatta atgatcttat caacgctttc
     5041 aaaattatga tttcaaaatc agagagtcta atttcaggcg aaagtatttc cattgggtcc
     5101 ggtcatgctg tcacgataaa agaatttgta gaaactgtcg caaagatgac aagttaccaa
     5161 ggcaatctac agtttggtgc aatccctact agagagaatg aattgatgta tagctgtgca
     5221 tcattggcga gaatacagga actcggttgg ttgtgccaat attcattaaa tagtgcaatt
     5281 aaagatacac taaacagaat gcgggtctga atggatatga aattttgtaa aaaccgttat
     5341 atcaatacag tcattttagg ggcaggcgtt gcggggttag gtgcagctct gaaagcccgt
     5401 gaagtaaata ttgaatatga aatttttgaa gcaaaaacat ctgcgggtgg tttgttagac
     5461 aattttgtca ttgatggata tcgttttgat aatgcagttc atcttagttt tgctacagaa
     5521 gagaaagtaa gagatgtttt tgatagaaca ccttatttct ctcattctcc agatgctgta
     5581 aattttgaaa cagataagtg gttaaaacat ccagtgcaga ataaccttta tcctcttcct
     5641 gcaattgaga aagtcacact cattgagtcc ctgattcatc gtcctgagag tgagcttgct
     5701 gataactacg aatcttggtt aattcaccag tatggtaatg aaattgccaa gcgataccct
     5761 atgcgttata cacggaaata ttggcagtgt aatgcgaatg aactatcggt tagttggatt
     5821 ggtaatcgtc tacggcgagc taagctgtca gaaatattat atggcgcatt cactgatgat
     5881 actcctaatg attattatgc aaaagaaatg cgttatccca aaaaaggagg gtttaaatct
     5941 tttattcaac ctcttataga tgagagcatt attaactata attatgaggt tactgagatt
     6001 gacttatctg ggaagactat caaattctct aatggagtca taatcagtta tgaaaattta
     6061 ataaatacat taccactacc actgtttatt gagttttgtg gagctaatgt acctacaagc
     6121 gtcaaaaaat ccgcaagtaa gttaggggca acatcattag atctaatatc tgttggcttc
     6181 aacaagtcta tcattaaaga tttatggttt tatatctatg atgaagatat ttatgcaagt
     6241 cgcgcatatt ctccctctgt taaatcatcg gataatgttc ctgacggttg cagttcgtta
     6301 cagtttgaaa tttataatcc cgggagagat agccagtata ctgtacagga attgaaagac
     6361 aatgttattt atgcaatgaa aaaaatggga gttgcaaata atgaagatat tgttttcttg
     6421 catcacaagc gtctcccatg gggtaatgtt gtattcaaaa aagatatgga aaagtatagg
     6481 gatattgttc gagaatacat ttttgacaat caagtgaaaa gtgtaggacg ttttggtgaa
     6541 tgggattatt tatggagtaa tcagagtttt cttagtggat atagttcaat ttaataattt
     6601 aataatttaa taatttaata attaaaagtt aaaagttaaa agttaaaagt taaaagttaa
     6661 aagttaaaag ttaaaagtta aaagttaaaa gttaaaagtt aaaagttaaa agttaaaagt
     6721 taatatacca tgattaattt tctttaaagt taaaaataaa taattgcagg ctaaaatgag
     6781 aataaattat caaatggtat gggggttatt aaatcaagga tgtaatatat tcattccatt
     6841 tgtaataatg tttatgtctt ataagtatct ccccttagaa atggctagtg tatgggttat
     6901 attcttatcg atgatatcac taattacttt gtttgatttt ggtttgtcac cagcaatagt
     6961 cagaaatgtt agctatgtga tatctggagc gcaaaatcta gttaaaagag gaatagatga
     7021 tattattata aaagatgtga tatcctaccc tcttttatct agattgttat ttgatataaa
     7081 acggatttat ttatacctat ctctaatagc atttttcatt atagtcattg gtggtctttg
     7141 gtacttttat tatatatcac ctctggatat aaaaatagaa gttgcatatt cttgggtttt
     7201 attctcaagt gcgttaatta taaatcttat ttacttatat tacgttcctg tcttaactgg
     7261 tttgggtgaa attgaaaatt cttataaagc aaatgttttt gggagaataa tttggttttt
     7321 tttaagcttg ctggttttta ttttttcacc atcaatatta ttattatctc tatcttttgt
     7381 tttttctgtg tttatcaata gatatttatg ctattttttt tatattagaa attcgcatgt
     7441 aaaagctatt gataagacag aaatggataa aaaatccacg gtaccattta ttggtcacaa
     7501 tgcggccaag ttgggggtgg taagtctagg ttcattttta ataaatagat caactacttt
     7561 gattgtaggc attgtttgcc ctatcgtcac tgctggtcaa tttgtactaa gtatgcaggt
     7621 tttctttgct ttaatggcta taagtaatat tttattaagt ataaaaatcc ctgaaatatc
     7681 gcaggccgta gccaaaaggg aacactacac tgtaaagatt ctgatatata aagtggttgc
     7741 tttctcttcg agtatttatc tcttgggatt tgtaacattt ttaatcttgg cagaatatgt
     7801 acttcctacg attggagtga gtttatcatt tctcccactc gactaccttc tcattcttgg
     7861 attaatctat tttttagaaa tgaatcactc catttgcgcc acaataataa ccagtaaaaa
     7921 taatgtccca ttcgtttttg catcgttatt ttctggtgga ctgataatat tattatccat
     7981 aatattatca gtccatttta aatatggtgt ggtcggattg attttggctc aaggaattgt
     8041 ccagttgatg tataataatt ggaagtggcc attaatggtt tatagtgaat tcattaaaaa
     8101 taatatagag gataggtgat aataccttta tgaaaagtaa tattataatt gataatagta
     8161 actcagatga tgttctactg actatagcaa tacccacata taagagattt ggtttgttaa
     8221 aggaaacact aaaaagtgta ttttcactgg aatttaatat tccagtagaa gtaattgtcg
     8281 ttgataacga tcctgaacat cctgaattag tgttatcaga aatggcagag tttgaacgtt
     8341 atgattttat atattataaa aatatagaaa actatgggat gttcggcaat tggaatcaat
     8401 gcttgaattt ggggagaggg aagttaatta ctatattaca tgatgatgat ctattatgtg
     8461 ctaactttcc tcgtgagtta gatcggttct taaaagaata tagttgtcat gatgatattc
     8521 cgttgatagg ctttgggcat tatttattgg atcaaagaaa aagtgaagat aaagtcaata
     8581 aaaatatttt atataaaata agtaaaaaaa tatttaatgc tttcagaaaa tatataataa
     8641 agccaaaggt ggtttctata acattagatg aaattttttg gggaaatata ttttgtggta
     8701 cacttggtgt tgtgatggac aggaataagg cgttatccat ttcaggcttc gatgaaaaaa
     8761 actaccctgt cagtgattat gatttttgga ttaggtggat tcaaaaatat ggaccaataa
     8821 aatataacaa aactaaagta tcctattata gaattctcga caatgaaagt atgagaccag
     8881 acgtcatttc aaatttcata aaaaaaactt atgagttaag gttgatgatg attaaagaaa
     8941 cacctttatt agttaatcaa gaaagtaatg ctataaattt gaaaaaactt gatgaatact
     9001 catttaatgt taactggagt cgggaggggg attttaatct cggtatatta gatactgtta
     9061 attacattta tattaaaatt aagtgtattt cttgtaagta ttttagtttt tggttacatt
     9121 aaaaattttc tttgaatgag tttttataat gatattttga ccattacgaa tattaggtta
     9181 tataatataa tcgaatattc tctttataat agaattataa agaagcatgc ccaataagac
     9241 ggacttcatc caaggaataa aagtaaatgg agatgtattt tattgtactg aaaaataatt
     9301 gaatatcctc aatgacaata aagagctaat tattactaga taaataaaaa atatatgccg
     9361 gtgagtattg aatataactg attttatgtc acaagaagat catcactttt cgctatgaag
     9421 atgtttatta ctggaatgca aaaaattgaa cttgaatgcg ccttcacaac ttcagttgtg
     9481 ataagcagat ttgtgattgc atcaaaactg ttattcttac ttttgaaggc tgatcttcgg
     9541 ctatgattgt gcaggctctg cgtcttcatt aaaccacggt aaccatcata tccatgagtt
     9601 cgtcaataaa tgcaaactca aatctgaaaa tggcggtttt aacagcctgc acaatgttgg
     9661 aatatttcag gcatgaacaa atggctacac tgtcatggtt ttacctataa agaactggtc
     9721 ggaatttcgc ataaatccat ctcattgtcg atagagcttg atataacaaa actcaattgg
     9781 ctaagaactg ggcattcgtc accaagatca aactgcatta tctgtcgcct tacagcccaa
     9841 tctgaatgcg atagagcgat tgtggaaagt gatgaaagaa tataagcgga ataatcgata
     9901 ctttggaaaa cgaatgattt tcgctgaacg agatacaaat ttttcagcac aacgattcct
     9961 gaaatagcag acttcttgtc gtccagaatt aacgatgatt tttaggtgct caaaccagca
    10021 tcttgaggat cattgggtat atactctaat aataacttat tataaaacgt tttttttgaa
    10081 aatagctata attttatttt tcttaaaaag caagcgaaat atagatggga tttaaatgaa
    10141 tattttaatt gtatatttag gccggaaagg tggtggcgca cactacacat atgaattagt
    10201 taatgaatta tcgaagaaaa cgaatgtgtc tttattagta tctaagcaag cagagaatat
    10261 taagtcttat gaaagtctaa atatatcact caatactata aatacattca atggtatgtt
    10321 ttcatttata ctctcaagct ttaaattgcc atttataaaa aataaaataa agaaaattat
    10381 tttagatgaa aagatagata tagtcatatc tacaatgaca catgtatgga atggttttat
    10441 ttttactcca aattttatga tgaaaatacc atatatattg acgatccatg atgctgtacc
    10501 tcattcagga gaggggaact ttattttaaa tttactcaac aataaggata taaaaaatgc
    10561 gaatgcatat atcgcattga ctgaacatgt caagaatcaa tttattaata tttatggaga
    10621 taagaaggat atatgcattt tgccattggg atcgttcaat tttaaaagtg gcgagataaa
    10681 aagttggtgt ggtgttaggc cattacggat tctattcttt ggtagaatac atgagtataa
    10741 aggcattgat ttgctattag actctatgat tattttacag gaaaaatatg atctagagtt
    10801 atccatttat ggacaaggcg atctttctga ttatgttgat aaaattgatg taataaaaaa
    10861 aataaatatt gaaaaccgat ggattggtga ttctgaagtt ggtgatatat tacaggcaca
    10921 tgatgtatgt gttataccgt ataaggatgc tagccaatct ggtgttatac ctgttgcaca
    10981 atctgctgga cttcctacga ttgtaaatcc tgtcgatgga ttaattgagc agatagaaaa
    11041 agataaaact agcttagtca cagatagggt cgactcagtt tcattagctt tatccataga
    11101 gaaaataatt aaaaatccag agttagtgaa taaattatct ataggttcac tagaatatgc
    11161 atccagaaaa ttaagttggg ttcctattgt taataaatta attacttata gtaaagaaac
    11221 tttaaatagt agtgacagat cctagtttta tcattaagta atagagtgag ttataagatg
    11281 tatattctat ttttagcgtt atataatata ttgagcttaa atatatgcta tataaaaaag
    11341 aatttattct actaatatta gtcaaggtgt tgttctcgtt tttcgctttt tttatatata
    11401 gtaatttttc ccaacttggg gactctaata gatatttaaa tgcaacactt aattttaata
    11461 acattctgga tagaactcaa tttgtagata atacgtttgc ttttctaaag tatgtaatgt
    11521 ctagttcatt attagttaat atttctatat ctgttctatt cggttattca tttttctatg
    11581 tttttaaaga tgttcttatt tttgtagata aaaaattatt atatatgtct ttccttcttc
    11641 caagttttca aatttggaca agcgttgcag ggaaagaaat tattgctgtg ataggattcc
    11701 ttttttttat aaagtgggtc ataaatattc aatttggcag ggataatcgt atacattatc
    11761 ttgttatagg tattttattc ggagtttttc ttaggccaca ttatggtatt gcttatattt
    11821 atcttgctat cagcgctatt attttaagta gaataaaatt cagagtattc tccaatgggt
    11881 tttatgtgtt gtcattgttt atcatagcta taatgttgtt tcttgtgtta gcgttaacag
    11941 tgaatatttg gagtgcgcag ttcttatcag ttttggatac tattgaaggc tattttttat
    12001 cctatgatgc ctctaattct aatagatatg atatcgagtg gggaacaatt tcagactatt
    12061 tttataatat aacatggggt ttttttattt caattattgg gcctacttta aatgaaacac
    12121 tcaatcgagt ggtttatctc ccattcttta tagaaggtat tttaagtttt atattaatga
    12181 ttgtcatatc ttatcgttta tataaatcga ctaatgaaaa tgtattatat agaaagttat
    12241 tttacttttc ttttcttccg gcacttatca tcatattaat gattcattat ccttttggac
    12301 tttttaatcc aggatctgcg ataagatata agcaaaacat tactccattg atatactttt
    12361 atccattact aatgctggca tgtattaata aatataaggt taagggatag tgcggtattt
    12421 ttatcgagaa aaattgattt atatttttct gtgtgggaat attatttact ctcttctctt
    12481 aataagatga gttgggattt taatgtcgat ttaattagtg tattggtctt tatattttta
    12541 ggctgaatgg gtatgagttt aattaggccc tgatatgtta ttttttggtt ggttaaaatg
    12601 aaacttaaga aaatacttct ttgcggtaat agttcatggt ctatgtataa ttttcgtttg
    12661 ggtgttatta aatttttaat ttctaatcaa tattctgttg ttattttagc tccaagagat
    12721 gattattcag ataagctaat atctattggt tgcaagttca tagatataaa cctgtctgca
    12781 caaggggtca atcctttcaa tgaattaaag tttttatttt ctttagtttc aatttacaga
    12841 gaagagaaac cagatttcat tattaactat acaattaaac ccaatatata tggatctttg
    12901 gcttcaaaag taaccaatat tccatcaata gctataacta cgggactcgg ttttgttttt
    12961 acacgtaaaa gtatagtgtc ttttttcgca aagctattat ataaaatagc tctatcttgt
    13021 tgtcaagaag tttggttttt aaatagtgat gatcaagacg tttttttgcg taaaaatatt
    13081 gtaaataaga ataagacaaa aatactctac agtgaaggaa ttgatgtaac tcatttttcg
    13141 ccaaggaaaa gaaatgatca tcatgatgaa gatacttttt gctttttact ggtagcaagg
    13201 atgttacggg ataaaggagt acctgagttt gtatctgctg ccagaattat taagaagaaa
    13261 tatcctaatg tatcttttcg tctattagga ttttgtgatg tagaaaatcc tagtgcgatt
    13321 actcgtagtg aaattgattc atgggttaat gaaggggttg tcgaatactt aggtgtaacc
    13381 gatgatgtta gacaatatat cgctgattcc cagtgtattg tattaccctc atcatataga
    13441 gaaggaattc ctcgaatttt aatggaggcg gcatcaatgg ctaaaccggt gataacaact
    13501 aataatgtag gatgccggga agttattctt gatgaagtaa ccggatatct ttgtgaagtt
    13561 aataatgtag actctctggt ttctgcatgt gaaaaattgc ttagtttaga tgaggcccag
    13621 attattgata tgggaaaaaa aggacgaaaa cttgtcgagg aaaaattttc tgaagaaaag
    13681 ataatctcac aatattctga atgcataaat tattatttaa tagaaaaatc aattaaatag
    13741 ataccccgct gagatataaa atatattatt tgtcaatgac gatctatatt tttatttgtt
    13801 tttttgcatt ttcctttaat tttttatggt taaatttttt aatcattctt acatatgtcg
    13861 atataataag tagtggtttt tcccattggc tgttaaagtg gttttattaa ttttttttaa
    13921 aatcgatgat attggctgta aaaatataac ctataggttt ttatatgaca aaggtgttta
    13981 tattaggttc caacggctat attggtaata atttaatgga gtcattgtgt gataatattg
    14041 aagtcattac tgttgggaga agtaatgcgg atatttatat aaatcttgag tctgacgatt
    14101 ttcaatcttt attaaataag gtggaattta aagataccgt tattttcctg tcagcaatat
    14161 catcaccaga tgaatgtaat aataactacg attattcata taaaataaat gttaaaaata
    14221 cgatttctct aatatctttg cttttggcta aaaatgtaag agtgatgttt tcatccagcg
    14281 atgcggtttt tggtgcaact cagaatttat gtgatgaaaa ttctgaaaaa aaaccatttg
    14341 gaaaatatgg agaaatgaag tccgaggtag aagactactt tacattagag gatgattttt
    14401 ttgtcgtaag attttcttat gttttaggga ggaatgataa gttttctatg atgattaaag
    14461 aattttatga gcaaggtaaa atacttgatg tttttgatgg gttcgaaaga aatgttattt
    14521 caataaacga tgtgactgca ggcataaaaa atatcatatg tgattgggat agtatcaaaa
    14581 caagaatagt gaatttttca gggaacgaat tagtaagtag acaagatatt gttaacgctc
    14641 tagttaaaga gaaatattta aatttgaaat ataagtttac agcggccccc gagagtttct
    14701 gggtaggaag acccaaaaaa attcatacca aaagtaacta tttagaatcg atattgaata
    14761 gaaagcttga gtcatatctg gaagtaatta aggaataaat atgaataatg ttttaattac
    14821 aggttttaca ggacaagtag gatcgcagtt agctgattat attttagaaa ataccgatga
    14881 tcacgttatt ggcatgatgc gctggcaaga gtcgatggat aacatctatc atcttactga
    14941 tagaattaat aaaaaagatc gaatttcaat acaatatgct gaccttaatg atttaatgtc
    15001 attatataat cttattgata ctgtaaggcc aaaattcatt tttcacctgg ctgctcaatc
    15061 ttttccgcgt acttcatttg atattccaat tgaaacgctt caaacaaata ttataggtac
    15121 tgctaatcta ttagagtgta tcagaaaact gaaacaacaa gatggatacg atcccgttgt
    15181 gcatgtgtgt tcttctagtg aagtatatgg cagggctaaa gttggtgagg cattaaatga
    15241 agatactcaa tttcatggtg caagccccta tagtatcagt aaaattggta ctgactacct
    15301 agggcaattc tacggtgaag catatggtat tagaactttt gtgactcgaa tggggacgca
    15361 tacaggacct cgtcgtagtg atgttttttt tgaaagtact gtagctaagc agattgctct
    15421 aattgaggct ggacatcaag agcctaaatt gaaagtaggg aatcttgcta gcgttaggac
    15481 tttccaagat gctcgagatg cagtccgtgc ttattatctg ttagcacttg aaagtggaaa
    15541 aggaaatata cccaatggag aagtatttaa tattgcaggt gatgaagcat tcaagctacc
    15601 tgaagttatt gaactacttt taagttttag tacacgaaat gatatagagg tagtgacgga
    15661 taccgatcgt ttgagaccta ttgatgcaga ttatcaaatg tttgatagca caaaaattaa
    15721 gtcatatatc aactggaaac ctgaaattaa ggctgctgat atgttcagag acttgctcca
    15781 acactggaga aatgaaattg catcaggtcg cattccatta aatcgctaat cttagggcat
    15841 tagtttatga aaataagaag taaagctcct ctacgtttag ggatagctgg tggtgggacg
    15901 gatgtatcac catacagtga tacctttggt ggttgtgttc ttaatgcaac aattaatatg
    15961 tatgcttatg catatattga tgatgaatta gatgaaaaca aggttatatt tgaggctgcc
    16021 gatcttggtt taagagagga aataaacctt gataaagaaa taaatataga aggtcaatta
    16081 aagctacata gggctgtata tctacgcgtg atgaaagatt actttggtgg agaattaaag
    16141 cctattagaa ttattacgca ctcagatgca cccgcaggaa gcgggcttgg ttcttcttca
    16201 accgttgtag tgtcaatgct agaagggtta cgtcagatgt attctcttcc tcttggtgaa
    16261 tatgatttag cgcaattagc atttaagatt gaacgagttg actgtggact ctctggaggc
    16321 aaacaggatc agtatgctgc tacctttggt ggttttaatt ttatggagtt ttacaaatgc
    16381 aatcgagtta tcgtaaatcc gttaagaatc cgtagatata tcattaacga acttgaatca
    16441 tctttgatac tatattttac aggagcatca agagattccg caaaaatcat taatgaacaa
    16501 atcaaatcat tagaggaaaa gaaaggttct aaacttgagg caatgcatag agtaaaagag
    16561 tctgcttata aaataaaaga atatttgctt aagtctgata tagatgctat gtcatctacc
    16621 tttcttgatg catggagaag caagaaggaa acatcatctt caataacaaa tcctatgatt
    16681 gaggaaattg agatggagat attcaatatt ggtgctaagt ctatgaaagt atctggcgca
    16741 ggtggtggag gatttatgat gatatttgtt gaacccgaga aaaaacatat tgtagaaaat
    16801 aaacttaaag cgtttggtgg tgaagtatat aagtttcagt ttgttgaaga gggagcatat
    16861 tcatggacaa tttaaattat attcaaaaat atttggaaaa tagcatctcc gttaaaagaa
    16921 cgttacaaga gtcaaaggag gttttagagc aagtttctct agtcactgat ttaataatag
    16981 aagcatatag aaatggtaat aaggtgattc ttgctggtaa cggtggtagt gcggcagatt
    17041 ctcagcatat tgctgctgaa tttgtaagtc gttttttctt tgaccgtcca ggtttgccag
    17101 cgatggctct aacaactgac acatcaatgt tgactgcaat tggaaatgat tatggttttg
    17161 ataaactgtt ttcacgacag ctacaggcac aaagtaggcc tggcgatgta tttatcggaa
    17221 ttagcacatc tggtaattcc gaaaatataa tcaatgcaat gaaactgact aaagagcttg
    17281 gtgtaacgag tgttgcttta tgtggtgaaa gtggaaaatt gaaagaaata gttgattatt
    17341 ctattaatgt accatcaaaa ataacacctt atattcaaga atgtcatatt tgtattggtc
    17401 atatgatttg tgcaattgtt gaaaaagtaa tttttgggtc ggaagataat taatatgtat
    17461 gatgtggtca ttttagccgg tggacttggg actagattaa aaagtgttag tggtgacatt
    17521 cctaagccta tggtggatat ttctggaaaa ccttttttgt atagacttat ggaatacctt
    17581 gaagatcagg gggtacaaag aataatttta tccttatcat ataaagcaga ttatattatt
    17641 gatagcgtta tcaaagacaa tccggttaat agcaaagtcg attttattat tgaaaatgaa
    17701 cctttaggga caggtggagc aataaaaaat gcttgtaaat atattgaggc aagcaagttt
    17761 atagttatca atggtgatac ttattgtgaa cttgattata aaaaattcat agagtcttca
    17821 cttgattcag atttacaaat atccggagtt gaagttgacg atgtttgtag atacggtagt
    17881 ttagatattg accatgattt tcatgtaaac tctatcgttg aaaaaggtcg tcaggggaca
    17941 ggaattatta atagtggtac ttatatacta tctaaaaaaa tcattgagga ttatcctcat
    18001 gataaattct cttttgagct tgatttttta cctaaattca ctggtgtctt taaggcattt
    18061 gttactaaag catatttcat tgatataggg atacctgaag actattataa agcatgtgag
    18121 aaatttaaat gaaaattgca tttttagatc gcgacggtgt aattaataaa gaagtgaatt
    18181 atctttataa gatagatgat tttgttttta cacctaattg tattgacggg ttaagaaggc
    18241 ttagggaaaa aaattttgaa atcgtaatta tcacaaatca ggctggcatt gccaaagggt
    18301 tttatagtgt cgatgactat aatgatctta cgttttggta cagagaaaaa ctgctatctt
    18361 atggagtaga tatattagat attttatatt gtcctcatca tccaaatgga tgtgtccctg
    18421 agtatagtat tgagtgtaac tgccgtaaac cgaaaacagg tttacttgag gaggtggcaa
    18481 aaaagtatca aattgatata aaagaatcaa ttttggttgg tgataaacaa agtgatttaa
    18541 acgctggtat tagtttcggc atatcaaaag tctatctagt tgaaactggg cacaaaattc
    18601 caaaagaaaa ctacaaaaaa tatcacgtgt attctgattt atcatgtatc ccattatgaa
    18661 aaaataagtc atatcactat gcctactcat actcacactt tgatgagttt tttttgggga
    18721 gaaatataaa gctgatttta taaactatta gatgtttttt agtggcatct gtatttttca
    18781 atatcggtta ttgcgggtta ctacttcgtt taagagaaaa tataaactgg ctgcttaata
    18841 atgaagctgg attttttaac caatctacat ttttacgaat gagctaatta tgaatgtaca
    18901 gtatgatttc tctgaggcac atgtttaacg ggttatgtaa tatattgatg aattatctta
    18961 aatgtttact tgctctattg gtgtcaataa ctcaccccat ttacatctgt aaccagaaaa
    19021 ataatattcc tccttgtgtg gtgttacatt ttgctagcct tttaggctac agttagcgct
    19081 agttttaggg tttaagttaa tataaactta cgtagatata caggtaatac tcaatgagta
    19141 ataaacaggc acgaagtaac cttgatagtc caataccgaa taactatgat ttttcaaatg
    19201 tatcttcttc aagaaatgaa attgatctct ttgaaatttt tggtgttgta tttaaatcaa
    19261 agttcaagat aatattaata acactatttt tcttaattag tggtttagtg gtctcatata
    19321 tcctccccca aaaatggaca agcactgcaa taatagctct tcctggtgat gagcaagttc
    19381 aagttctgga tgaactaatc acaaatctga ccgtgcttga tataaaggtt gatgtgagtg
    19441 ctaattattt gctgtcaaca ttcaaacaaa atttcgattc tcaagatctc cgtgaacaat
    19501 atttagtaaa tactaattac tttaaacgtt tgatgaagaa taatccagaa gatggtttgg
    19561 ataaaagagc gttaatagag cgaatcgtaa atgaaaatat ttcttcggtt aacccattga
    19621 aagataaaac cgagggtgaa aatgaatatc gctattataa attatcatat agtgcaagca
    19681 caccgacaga cgctcgtgac ttgttgcaag gctctattaa ctatgtaaat accatcgtta
    19741 atgctgatgt tttccgaaaa atacagcgag cagtggattt agccaagggt atcggtacag
    19801 ataaatactc tatggaatta ttgaaagcta gaaataacca aaaagttaaa attgagcgct
    19861 taaggtatgc ttcttctatc gctgatgccg caggcgtaaa aaaaccagtt tacagcaatg
    19921 gctcagccat tagtgatgat ccagacttcc ctattactat gggatccgat gcgctgaacc
    19981 gtaaactgga aatagagaag tcagttatcg acctggcttc aatcaatact gaacttctaa
    20041 accgtaagtt gtatttggat aaattaaata ggttagaaat tcctaatgtt aatattgtgc
    20101 catttaaata tttgcaacag ccaacggaac ccactaaaag agatgcccct aagcgcgcat
    20161 tgattgtgat tctgtttgcc ctggtcggtc ttatgggttc tgtcggtttt gttttagttg
    20221 agcactttgt gcgtgaacgg aagcgagaag aagaggggct taagctctct caaactaagg
    20281 aataggtttt aaacgaattt atctaacggc tgggtgaggt ttctcatctg gccgttctgt
    20341 tttatcgctc tgtattattt tactattttt ccgtttttaa gttagctgct actatttgct
    20401 tgtaactaat tcccctgcat tatgcttccc agcaaccctt atgctaaaat tcgttatctt
    20461 ttcatcgcta gatttttaac tcaaaacaat gaaatttcct ggtaagcgca a
//
