LOCUS       AF461770               20125 bp    DNA     linear   BCT 24-JUL-2016
DEFINITION  Yersinia pseudotuberculosis serogroup IIA O-antigen gene cluster,
            complete sequence.
ACCESSION   AF461770 L01777
VERSION     AF461770.1
KEYWORDS    .
SOURCE      Yersinia pseudotuberculosis
  ORGANISM  Yersinia pseudotuberculosis
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Yersiniaceae; Yersinia.
REFERENCE   1  (bases 1 to 20125)
  AUTHORS   Kessler,A.
  TITLE     The 3,6 dideoxyhexose pathway genes of Yersinia pseudotuberculosis
            serogroup IIA
  JOURNAL   Thesis (1993) Department of Microbiology, University of Sydney,
            Australia
REFERENCE   2  (bases 1 to 8845)
  AUTHORS   Kessler,A.C., Haase,A. and Reeves,P.R.
  TITLE     Molecular analysis of the 3,6-dideoxyhexose pathway genes of
            Yersinia pseudotuberculosis serogroup IIA
  JOURNAL   J. Bacteriol. 175 (5), 1412-1422 (1993)
   PUBMED   8444803
REFERENCE   3  (bases 1 to 20125)
  AUTHORS   Hobbs,M. and Reeves,P.R.
  TITLE     The JUMPstart sequence: a 39 bp element common to several
            polysaccharide gene clusters
  JOURNAL   Mol. Microbiol. 12 (5), 855-856 (1994)
   PUBMED   8052136
REFERENCE   4  (bases 1 to 20125)
  AUTHORS   Liu,D., Lindqvist,L. and Reeves,P.R.
  TITLE     Transferases of O-antigen biosynthesis in Salmonella enterica:
            dideoxyhexosyltransferases of groups B and C2 and acetyltransferase
            of group C2
  JOURNAL   J. Bacteriol. 177 (14), 4084-4088 (1995)
   PUBMED   7541787
REFERENCE   5  (bases 1 to 20125)
  AUTHORS   Hobbs,M. and Reeves,P.R.
  TITLE     Genetic organisation and evolution of Yersinia pseudotuberculosis
            3,6-dideoxyhexose biosynthetic genes
  JOURNAL   Biochim. Biophys. Acta 1245 (3), 273-277 (1995)
   PUBMED   8541300
REFERENCE   6  (bases 1 to 20125)
  AUTHORS   Reeves,P.R., Hobbs,M., Valvano,M.A., Skurnik,M., Whitfield,C.,
            Coplin,D., Kido,N., Klena,J., Maskell,D., Raetz,C.R. and Rick,P.D.
  TITLE     Bacterial polysaccharide synthesis and gene nomenclature
  JOURNAL   Trends Microbiol. 4 (12), 495-503 (1996)
   PUBMED   9004408
REFERENCE   7  (bases 1 to 20125)
  AUTHORS   Pacinelli,E., Wang,L. and Reeves,P.R.
  TITLE     Relationship of Yersinia pseudotuberculosis O antigens IA, IIA, and
            IVB: the IIA gene cluster was derived from that of IVB
  JOURNAL   Infect. Immun. 70 (6), 3271-3276 (2002)
   PUBMED   12011023
REFERENCE   8  (bases 1 to 20125)
  AUTHORS   Hobbs,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-FEB-1993) Department of Microbiology, University of
            Sydney, Building G08, Sydney, NSW 2006, Australia
REFERENCE   9  (bases 1 to 20125)
  AUTHORS   Pacinelli,E., Wang,L. and Reeves,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2001) Microbiology, University of Sydney, Sydney,
            NSW 2006, Australia
  REMARK    Nucleotide and amino acid sequences updated by submitter
COMMENT     On Sep 26, 2002 this sequence version replaced L01777.1.
FEATURES             Location/Qualifiers
     source          1..20125
                     /organism="Yersinia pseudotuberculosis"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:633"
                     /note="serogroup: IIA"
     gene            <1..235
                     /gene="hemH"
     CDS             <1..235
                     /gene="hemH"
                     /codon_start=2
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="AAB49397.1"
                     /translation="TPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREF
                     FLHAGGEKFEYIPALNDDEGHIALLEQLIRHNI"
     mobile_element  1..10009
                     /note="remnants of an IS related to IS630"
                     /mobile_element_type=insertion sequence:IS630-like
     misc_feature    586..623
                     /note="JUMPstart"
                     /citation=[3]
     gene            833..1822
                     /gene="ddhD"
     CDS             833..1822
                     /gene="ddhD"
                     /note="DdhD; formerly known as rfbI"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-6-deoxy-delta-3,4-glucoseen reductase"
                     /protein_id="AAB49398.1"
                     /translation="MSLNVKLHPSGIIFTSDGTSTILDAALDSNIHIEYSCKDGTCGS
                     CKAILISGEVDSAENTFLTEEDVAKGAILTCCSKAKSDIELDVNYYPELSHIQKKTYP
                     CKLDSIEFIGEDIAILSLRLPPTAKIQYLAGQYIDLIINGQRRSYSIANAPGGNGNIE
                     LHVRKVVNGVFSNIIFNELKLQQLLRIEGPQGTFFVREDNLPIVFLAGGTGFAPVKSM
                     VEALINKNDQRQVHIYWGMPAGHNFYSDIANEWAIKHPNIHYVPVVSGDDSTWTGATG
                     FVHQAVLEDIPDLSLFNVYACGSLAMITAARNDFINHGLAENKFFSDAFVPSK"
     repeat_region   1822..1839
                     /rpt_type=inverted
     gene            1848..2633
                     /gene="ddhA"
     CDS             1848..2633
                     /gene="ddhA"
                     /note="DdhA; formerly known as rfbF"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-P-cytidylyltransferase"
                     /protein_id="AAB49399.1"
                     /translation="MEIQVKAVILAGGLGTRLSEETVVKPKPMVEIGGKPILWHIMKL
                     YSSYGINDFVICCGYKGYVIKEYFANYFMHMSDITFCMRDNEMIVHQKRVEPWNVTLV
                     DTGEDSMTGGRLRRVKDYVKDDEAFCFTYGDGVSDVNIAELIEFHKSHGKQATLTATY
                     PPGRFGALDIKDKQVRSFKEKPKGDGALINGGYFVLSPKVIDLIDGDKSTWEQEPLMT
                     LAAQGELMAFEHAGFWQPMDTLRDKIYLHELWEEGRAPWKVWE"
     gene            2536..3711
                     /gene="ddhB"
     CDS             2536..3711
                     /gene="ddhB"
                     /note="DdhB; formerly known as rfbG"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose-4,6-dehydratase"
                     /protein_id="AAN23079.1"
                     /translation="MPVSGSQWIRCVTRFICMNYGKKAGHLGRYGNNKMINNSFWQGK
                     RVFVTGHTGFKGGWLSLWLQTMGATVKGYSLAPPTVPSLFETARVADGMQSEIGDIRD
                     QNKLLEAIREFQPEIVFHMAAQPLVRLSYSEPVETYSTNVMGTVYLLEAIRHVGGVKA
                     VVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYRNSFFNPANYGQH
                     GTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPVIIRNPHAIRPWQHVLEPLSGY
                     LLLAQKLYTDGAEYAEGWNFGPNDADATPVKNIVEQMVKYWGEGASWQLDGNAHPHEA
                     HYLKLDCSKAKMQLGWHPRWTLNTTLEYIVGWHKNWLSGTDMHEYSITEINNYMNTK"
     gene            3729..5042
                     /gene="ddhC"
     CDS             3729..5042
                     /gene="ddhC"
                     /note="DdhC; formerly known as rfbH"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-4-keto-6-deoxy-D-glucose-3-dehydrase"
                     /protein_id="AAB49401.1"
                     /translation="MSQEELRQQIAELVAQYAETAMAPKPFEAGKSVVPPSGKVIGTK
                     ELQLMVEASLDGWLTTGRFNDAFEKKLGEYLGVPYVLTTTSGSSANLLALTALTSPKL
                     GVRALKPGDEVITVAAGFPTTVNPTIQNGLIPVFVDVDIPTYNVNASLIEAAVSDKTK
                     AIMIAHTLGNLFDLAEVRRVADKYNLWLIEDCCDALGSTYDGKMAGTFGDIGTVSFYP
                     AHHITMGEGGAVFTQSAELKSIIESFRDWGRDCYCAPGCDNTCKKRFGQQLGSLPFGY
                     DHKYTYSHLGYNLKITDMQAACGLAQLERIEEFVEKRKANFKYLKDALQSCADFLELP
                     EATENSDPSWFGFPITLKEDSGVSRIDLVKFLDEAKVGTRLLFAGNLTRQPYFHDVKY
                     RVVGELTNTDRIMNQTFWIGIYPGLTHDHLDYVVSKFEEFFGLNF"
     repeat_region   5056..5071
                     /rpt_type=inverted
     gene            5082..5933
                     /gene="abe"
     CDS             5082..5933
                     /gene="abe"
                     /note="Abe; formerly known as rfbJ"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-abequose synthase"
                     /protein_id="AAB49402.1"
                     /translation="MRIVLTGGSGYIGSSLTPVLIKKYGRVYNIGRNTISEVSINGSK
                     EYCEFTYESLFDSLVELSPDLVINLAAGYYNDSGAPDLNVIDGNLKIPFIILEYFKSC
                     NYGRFINIGSYWEFSCSGRGVKGVNPYGIIKSTVRRLLDYYSKYNVIYTNLILYGSYG
                     DNDHRGKIVDCIIDAVNSNETLKLSPGEQKLNLVYIDDIIEAILYIVSSDNGQYDNET
                     LSIYTPTEHTVKEIVCFINEIKDNNLSLGGGRYRNDEVMAPDYKYRNIFHAKDKLKEY
                     ITSKIKK"
     misc_feature    6443..6754
                     /note="part of non-functional tyv gene which has
                     accumulated numerous mutations"
     CDS             6755..7375
                     /note="non-functional gene; orf6.8; remaining coding
                     sequence of mutated non-functional tyv gene"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
     gene            7407..8720
                     /gene="wzx"
     CDS             7407..8720
                     /gene="wzx"
                     /note="putative O antigen export protein; Wzx; previously
                     called rfbX and orf7.4; TTG initiation codon"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="AAB49403.1"
                     /translation="MRVPTHIIVAASAWGSRLVSIFIQFYSIKILLDLLGTEGYAVFT
                     VIGSLVGWFLLADFGLGNSLQNQISYRRANHQEYQDLVLSAVIAIIPIFILFIILILT
                     LSPYISEFLLGGFDFLNNNQRSNIFKVASFIFLTTSIGNLAYKIWFSEHKGWVSNIIP
                     ALSSIVGLVFLMRLPSDGSNISEDIIFSIYCFYIPAAFFGVISTLFKVIPYLKCKNFL
                     NKLTLYTLIKNGGGFFLFSVLSALVLQVDYIVMSQTLVERDLVTYNIMSKTFGLINFI
                     YAALLQSLWPVCAEASSKLRFDNFYKIEKKYISFGFIIVIASSFVIFLLKDFIVNILA
                     PGKDFYFPISLIILFSFYQVVRVWTDTYAMFLMSIGKLKPLWISVPFQAVLSGSLQWV
                     GAVNYGLVGLLCGLIASFLITVSWWLPFSFRSTVDRIVKDKRLDE"
     gene            8713..9750
                     /gene="wbyA"
                     /gene_synonym="orf8.7"
     CDS             8713..9750
                     /gene="wbyA"
                     /gene_synonym="orf8.7"
                     /note="WbyA"
                     /citation=[5]
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAB49404.1"
                     /translation="MSNIKISFCIPTYNRSELLSELIESIVSQCKNRNDIEICISDNA
                     SSDNTSEMIAKWKESTDTPIVYQVNKENIGPDRNYLAAVDLASGEYCWLFGSDDRLLS
                     DAIIKMDEHINEGHDIYIVDRIECDFNMKPFSHRTWMSTGSKLYNTSKRTDLIEYFNN
                     SYAVGAVFSYLSSIIVKRSRWNRVKFNPKFIGSCYAHVFYLLDIVNNGAELKYVKSAF
                     VLSRGGNDSFAANGLIKRIEIDFDGYFLLGNEFFSNDFYLNSKFKAILLKEHPVIHTC
                     IKTAMIGEFQDLNKIKRFYIELGIAPYYVSIIYFFKPIYQLANKMKLSFFYKKLRKKI
                     TFKKGSFNSID"
     gene            9785..10894
                     /gene="wbyB"
                     /gene_synonym="orf9.8"
     CDS             9785..10894
                     /gene="wbyB"
                     /gene_synonym="orf9.8"
                     /note="WbyB"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAN23080.1"
                     /translation="MNILIVYLGRKGGGAHYTYELVNELSKKTNVSLLVSKQAENIKS
                     YESLNISLNTINTFNGMFSFILSSFKLPFIKNKIKKIILDEKIDIVISTMTHVWNGFI
                     FTPNFMMKIPYILTIHDAVPHSGEENFILNLLNNKDIKNANAYIALTEHVKNQFINIY
                     GDKKDICILPLGSFNFKSGEIKSWCGVRPLRILFFGRIHEYKGIDLLLDSMIILQEKY
                     DLELSIYGQGDLSDYVDKIDVIKKINIENRWIGDSEVGDILQAHDVCVIPYKDASQSG
                     VIPVAQSAGLPTIVNPVDGLIEQIEKDKTSLVTDRVDSVSLALSIEKIIKNPELVNKL
                     SIGSLEYASRKLSWVPIVNKLITYSKETLNSSDRS"
     gene            10974..12059
                     /gene="wzy"
     CDS             10974..12059
                     /gene="wzy"
                     /note="Wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="AAN23078.1"
                     /translation="MLYKKEFILLILVKVLFSFFAFFIYSNFSQLGDSNRYLNATLNF
                     NNILDRTQFVDNTFAFLKYVMSSSLLVNISISVLFGYSFFYVFKDVLIFVDKKLLYMS
                     FLLPSFQIWTSVAGKEIIAVIGFLFFIKWVINIQFGRDNRIHYLVIGILFGVFLRPHY
                     GIAYIYLAISAIILSRIKFRVFSNGFYVLSLFIIAIMLFLVLALTVNIWSAQFLSVLD
                     TIEGYFLSYDASNSNRYDIEWGTISDYFYNITWGFFISIIGPTLNETLNRVVYLPFFI
                     EGILSFILMIVISYRLYKSTNENVLYRKLFYFSFLPALIIILMIHYPFGLFNPGSAIR
                     YKQNITPLIYFYPLLMLACINKYKVKG"
     gene            12247..13380
                     /gene="wbyC"
     CDS             12247..13380
                     /gene="wbyC"
                     /note="WbyC"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AAN23070.1"
                     /translation="MKLKKILLCGNSSWSMYNFRLGVIKFLISNQYSVVILAPRDDYS
                     DKLISIGCKFIDINLSAQGVNPFNELKFLFSLVSIYREEKPDFIINYTIKPNIYGSLA
                     SKVTNIPSIAITTGLGFVFTRKSIVSFFAKLLYKIALSCCQEVWFLNSDDQDVFLRKN
                     IVNKNKTKILYSEGIDVTHFSPRKRNDHHDEDTFCFLLVARMLRDKGVPEFVSAARII
                     KKKYPNVSFRLLGFCDVENPSAITRSEIDSWVNEGVVEYLGVTDDVRQYIADSQCIVL
                     PSSYREGIPRILMEAASMAKPVITTNNVGCREVILDEVTGYLCEVNNVDSLVSACEKL
                     LSLDEAQIIDMGKKGRKLVEEKFSEEKIISQYSECINYYLIEK"
     gene            13614..14447
                     /gene="dmhB"
     CDS             13614..14447
                     /gene="dmhB"
                     /note="DmbH"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23071.1"
                     /translation="MTKVFILGSNGYIGNNLMESLCDNIEVITVGRSNADIYINLESD
                     DFQSLLNKVEFKDTVIFLSAISSPDECNNNYNYSYKINVKNTISLISLLLAKNVRVMF
                     SSSDAVFGATQNLCDENSEKKPFGKYGEMKSEVEDYFTLEDDFFVVRFSYVLGRNDKF
                     SMMIKEFYEQGKILDVFDGFERNVISINDVTAGIKNIICDWDSIKTRIVNFSGNELVS
                     RQDIVNALVKEKYLNLKYKFTAAPESFWVGRPKKIHTKSNYLESILNRKLEPYLEVIK
                     E"
     gene            14450..15478
                     /gene="dmhA"
     CDS             14450..15478
                     /gene="dmhA"
                     /note="DmhA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23072.1"
                     /translation="MNNVLITGFTGQVGSQLADYILENTDDHVIGMMRWQESMDNIYH
                     LTDRINKKDRISIQYADLNDLMSLYNLIDTVRPKFIFHLAAQSFPRTSFDIPIETLQT
                     NIIGTANLLECIRKLKQQDGYDPVVHVCSSSEVYGRAKVGEALNEDTQFHGASPYSIS
                     KIGTDYLGQFYGEAYGIRTFVTRMGTHTGPRRSDVFFESTVAKQIALIEAGHQEPKLK
                     VGNLASVRTFQDARDAVRAYYLLALESGKGNIPNGEVFNIAGDEAFKLPEVIELLLSF
                     STRNDIEVVTDTDRLRPIDADYQMFDSTKIKSYINWKPEIKAADMFRDLLQHWRNEIA
                     SGRIPLNR"
     gene            15496..16524
                     /gene="hddA"
     CDS             15496..16524
                     /gene="hddA"
                     /note="HddA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23073.1"
                     /translation="MKIRSKAPLRLGIAGGGTDVSPYSDTFGGCVLNATINMYAYAYI
                     DDELDENKVIFEAADLGLREEINLDKEINIEGQLKLHRAVYLRVMKDYFGGELKPIRI
                     ITHSDAPAGSGLGSSSTVVVSMLEGLRQMYSLPLGEYDLAQLAFKIERVDCGLSGGKQ
                     DQYAATFGGFNFMEFYKCNRVIVNPLRIRRYIINELESSLILYFTGASRDSAKIINEQ
                     IKSLEEKKGSKLEAMHRVKESAYKIKEYLLKSDIDAMSSTFLDAWRSKKETSSSITNP
                     MIEEIEMEIFNIGAKSMKVSGAGGGGFMMIFVEPEKKHIVENKLKAFGGEVYKFQFVE
                     EGAYSWTI"
     gene            16512..17102
                     /gene="gmhA"
     CDS             16512..17102
                     /gene="gmhA"
                     /note="GmhA"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23074.1"
                     /translation="MDNLNYIQKYLENSISVKRTLQESKEVLEQVSLVTDLIIEAYRN
                     GNKVILAGNGGSAADSQHIAAEFVSRFFFDRPGLPAMALTTDTSMLTAIGNDYGFDKL
                     FSRQLQAQSRPGDVFIGISTSGNSENIINAMKLTKELGVTSVALCGESGKLKEIVDYS
                     INVPSKITPYIQECHICIGHMICAIVEKVIFGSEDN"
     gene            17104..17781
                     /gene="hddC"
     CDS             17104..17781
                     /gene="hddC"
                     /note="HddC"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23075.1"
                     /translation="MYDVVILAGGLGTRLKSVSGDIPKPMVDISGKPFLYRLMEYLED
                     QGVQRIILSLSYKADYIIDSLIKDNPVNSKVDFIIENEPLGTGGAIKNACKYIEASKF
                     IVINGDTYCELDYKKFIESSLDSDLQISGVEVDDVCRYGSLDIDHDFHVNSIVEKGRQ
                     GTGIINSGTYILSKKIIEDYPHDKFSFELDFLPKFTGVFKAFVTKAYFIDIGIPEDYY
                     KACEKFK"
     gene            17778..18308
                     /gene="gmhB"
     CDS             17778..18308
                     /gene="gmhB"
                     /note="GmhB"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 6-deoxy-D-mannoheptose pathway protein"
                     /protein_id="AAN23076.1"
                     /translation="MKIAFLDRDGVINKEVNYLYKIDDFVFTPNCIDGLRRLREKNFE
                     IVIITNQAGIAKGFYSVDDYNDLTFWYREKLLSYGVDILDILYCPHHPNGCVPEYSIE
                     CNCRKPKTGLLEEVAKKYQIDIKESILVGDKQSDLNAGISFGISKVYLVETGHKIPKE
                     NYKKYHVYSDLSCIPL"
     gene            18783..19934
                     /gene="wzz"
     CDS             18783..19934
                     /gene="wzz"
                     /note="Wzz"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant-like protein"
                     /protein_id="AAN23077.1"
                     /translation="MSNKQARNNLDNPMPNNYDFSNVSSSRNEIDLFEIFGVVFKSKF
                     KIILITLFFLISGLVVSYILPQKWTSTAIIALPGDEQVQVLDELITNLTVLDIKVDVS
                     ANYLLSTFKQNFDSQDLREQYLVNTNYFKRLMKNNPEDGLDKRALIERIVNENISSVN
                     PLKDKTEGENEYRYYKLSYSASTPTDARDLLQGSINYVNTIVNADVFRKIQRAVDLAK
                     GIGTDKYSMELLKARNNQKVKIERLRYASSIADAAGVKKPVYSNGSAISDDPDFPITM
                     GSDALNRKLEIEKSVIDLASINTELLNRKLYLDKLNRLEIPNVNIVPFKYLQQPTEPT
                     KRDAPKRALIVILFALVGLMGSVGFVLVEHFVRERKREEEGLKLSQTKE"
BASE COUNT     6400 a   2936 c   3970 g   6819 t
ORIGIN
        1 gacaccttat accgatgaaa ccctaaaaag tttaccttct caaggcgtta agcatattca
       61 gcttatttgc ccaggtttct ctgccgattg tctggaaact ctggaagaaa taaaagagca
      121 aaatcgagag tttttcttgc atgcgggcgg agagaagttt gaatacatcc cagcattgaa
      181 tgacgacgag gggcatattg ccctgttaga acagttaatt cgacataata tataatcgct
      241 gctaaacatt acatcttttg gtagtttatc acactcaaaa atttcacatt ttcaatccaa
      301 tgaagagtca gtaaaaaata taaatagtgg gtaaaatgtt gtcgtggtta gtatttgttc
      361 attttgatct gatctcttta tcaaatagaa catgatgtac atcacatctc tcttgtaata
      421 tagggatata agtacgatta ttagcacgaa attttgggtt tttatgtcat agggtgctta
      481 acttaactta catctgtaat ttcggaatgc tccgacacct gttttaggta aaagcgcgta
      541 ccttcaaggc cctgttatgg ttgtagacct aaagcttcat atcaccagtg cattggtagc
      601 tgtaagccaa gggcggtagc gtggggggga tagaacccca atagttgcct tttactctgg
      661 aaccggcagg aagaagacct tctacaattt tttactttag tgatttttaa ccgtacttct
      721 ttatcaaaaa ttatttgctt ttttgtttct attttagtca ctgaattttt ttgacttaag
      781 tttgtattga gtacgtctaa taaaccttac ataatatatt tggacttatt ttatgtcatt
      841 aaatgttaag ctgcatccat caggtattat ttttacttcc gatggaacat ctacaatatt
      901 agatgcggct ctggatagta atatacatat tgaatacagc tgcaaagatg gaacctgtgg
      961 ttcttgtaag gcaatattga tttctggtga agtagacagt gcggaaaata cctttttaac
     1021 tgaggaagat gttgctaaag gtgcaatcct cacttgttgc tctaaggcta aatctgatat
     1081 tgagttagat gttaattatt atccagagtt aagtcatata caaaaaaaaa cttatccatg
     1141 taaattagat agcattgaat ttattggtga agatattgcc attctctcct tacgtttgcc
     1201 accaacggcc aaaatacagt atctggcggg ccaatacatt gatttaatta ttaatggaca
     1261 gcgccgtagt tactctattg ctaatgctcc aggtggtaat ggcaatatcg aattacacgt
     1321 acgtaaagtt gttaatggtg tattcagcaa catcattttt aatgagttaa aattacagca
     1381 acttttacga attgaaggtc ctcaagggac ctttttcgtt cgtgaagata atctccctat
     1441 tgtttttctt gctggtggaa caggttttgc accagtgaaa tcaatggttg aggcgttgat
     1501 caataaaaat gaccaacggc aggttcatat ctattgggga atgccagcag ggcataattt
     1561 ctattctgac attgccaatg agtgggctat aaaacaccct aacattcatt atgtgcctgt
     1621 tgtatcaggc gatgatagta cttggaccgg agccactggt tttgtacatc aagcggtgct
     1681 tgaagatata cccgatctca gcttatttaa tgtttatgcc tgtggttcat tagcgatgat
     1741 tactgctgct cgtaatgatt tcatcaatca tggattagct gaaaataaat ttttctctga
     1801 tgcctttgtg ccatcaaaat aactttgaga gatcaaagta atacgtaatg gagattcaag
     1861 tgaaagcagt cattttggcc ggaggccttg gaacccgtct tagtgaagag accgtagtaa
     1921 aaccaaaacc aatggtagag attggtggga agcctattct ctggcatatt atgaaacttt
     1981 actcttctta tggcatcaat gatttcgtta tttgctgtgg ttataaaggc tatgtcatta
     2041 aagaatattt tgcgaattac tttatgcaca tgtcggatat taccttctgc atgcgtgata
     2101 atgaaatgat agtacaccaa aagcgagtcg aaccctggaa tgtcacgtta gtagacaccg
     2161 gcgaagattc tatgaccggt ggccgactga ggcgtgtaaa agattacgtc aaagacgatg
     2221 aggctttctg tttcacctat ggtgatggtg tgagtgacgt caatattgct gaattaattg
     2281 aattccataa gagccacggc aagcaagcca cattaacggc aacctatccc ccaggccgtt
     2341 ttggtgcgct ggatattaaa gataaacaag tacgtagttt taaagaaaaa ccaaaaggcg
     2401 atggcgcatt gatcaacggc ggttattttg ttttgtcgcc taaagttatc gatctgatcg
     2461 atggtgataa atctacttgg gagcaggaac ctttaatgac attagctgcg cagggggagt
     2521 tgatggcgtt tgaacatgcc ggtttctggc agccaatgga tacgttgcgt gacaagattt
     2581 atctgcatga actatgggaa gaaggcaggg caccttggaa ggtatgggaa taacaaaatg
     2641 attaataata gtttctggca aggtaaacgg gtttttgtaa caggccatac tgggtttaaa
     2701 ggtggctggt tgagtttatg gttgcaaacc atgggggcaa cggtaaaagg ttactctttg
     2761 gcccccccca cggtgcctag cctatttgag accgcacgag ttgccgacgg gatgcaatcg
     2821 gaaatcggtg atattcgtga tcaaaacaaa ttattagaag caatccgcga attccaacca
     2881 gaaattgttt tccacatggc tgctcagcca ctggtccgtc tatcctattc cgaacccgtt
     2941 gaaacctact cgacgaatgt tatgggtacc gtttatttac tggaagctat tcgccatgtt
     3001 ggtggcgtca aagcggtggt caatatcacc agtgataaat gctacgataa taaagagtgg
     3061 atctggggct atcgcgaaaa tgaagcgatg ggggggtatg atccttactc caacagtaaa
     3121 ggttgtgcgg aattagtgac gtcatcctac cgtaattcgt tcttcaatcc agcgaactat
     3181 ggccagcatg gcactgccgt agcgacagtg cgtgcgggta atgtcatcgg tggtggcgat
     3241 tgggcattgg atcgcatcgt tccagatatt cttcgggcgt ttgaacagtc ccaaccagtg
     3301 attattcgca acccacatgc cattcgccca tggcagcatg tgttggagcc tttgtcgggt
     3361 tatttgctgt tggcacagaa gttatatact gacggtgctg aatatgccga aggttggaac
     3421 tttggtccta acgatgctga tgctactcca gtaaaaaaca ttgttgaaca aatggtgaaa
     3481 tattggggag agggtgcaag ctggcaatta gatggcaatg ctcaccctca tgaagctcat
     3541 tatctgaaac tggattgttc aaaagctaaa atgcaacttg gctggcatcc tcgctggacc
     3601 ttgaatacta cgctcgaata tattgtgggc tggcacaaga actggttatc aggcacagat
     3661 atgcatgaat acagtattac tgaaattaat aattacatga acactaaatg atttgaggtc
     3721 atagataaat gagtcaagaa gaattacgtc aacagattgc tgagctggtt gctcagtacg
     3781 ctgaaacggc tatggcccct aagccatttg aagcaggtaa gagtgtcgtt ccaccttcag
     3841 gtaaagttat tggtaccaaa gaactccagt taatggttga agcttcttta gacggttggc
     3901 taacaacggg ccgttttaat gacgcttttg agaaaaaact aggcgagtat ttgggcgttc
     3961 cttatgttct gactacaact tctggctctt cagctaactt attggctttg accgcgctga
     4021 cctcacctaa attaggggta cgggcgttga agccaggtga cgaagttatt actgttgccg
     4081 caggttttcc aaccacagta aacccaacta ttcagaatgg gttaattcct gtctttgttg
     4141 atgttgatat tccaacttac aatgtaaatg ctagcctgat tgaagcggcg gttagtgata
     4201 aaaccaaagc tattatgatt gcccatacat taggtaatct attcgatcta gctgaagttc
     4261 gccgagtagc tgataaatat aacctgtggt taattgaaga ctgctgcgat gcgttgggtt
     4321 ccacctacga tggaaaaatg gctggtacat ttggcgatat tggtaccgtt agcttctatc
     4381 ccgctcatca tatcaccatg ggtgaaggtg gggcggtatt tacacaatcg gcggaactga
     4441 agagtatcat cgaatctttc cgtgattggg gtcgtgattg ttattgtgct ccaggctgtg
     4501 acaacacatg taaaaagcgt ttcggccagc aacttggctc tttaccattc ggttatgatc
     4561 ataaatatac ttattcccat ttaggctata acctaaaaat cacagatatg caggctgcct
     4621 gtggtttggc gcaactagag cgcatagaag agtttgttga aaaacgtaaa gctaacttta
     4681 aataccttaa agacgcactc caatcttgcg ctgactttct tgagttacca gaagcgactg
     4741 aaaattcaga tccatcatgg tttggtttcc ctatcactct gaaagaagat agcggagtta
     4801 gccgcattga tctggttaaa ttccttgatg aagctaaagt gggaactcgc ctactatttg
     4861 ccggtaattt aactcgccag ccgtatttcc atgatgtgaa ataccgtgtt gttggtgaat
     4921 tgacaaacac cgatagaatt atgaatcaaa ctttctggat tggtatttac ccaggcctga
     4981 cacatgatca tttggattat gttgtgagta agtttgaaga gttctttggt ttgaattttt
     5041 aatctaacat ggttggccag tgaatactgg ctaataataa aatgagaata gttctgactg
     5101 gaggaagcgg ctatatcggt agctccctca cacctgtatt aataaaaaaa tatggtcgag
     5161 tatataatat tggcagaaat accataagtg aagtatcaat taatggtagt aaggaatatt
     5221 gtgaattcac gtatgaatca ttgtttgact ctttagttga actatcacct gacctagtta
     5281 ttaatttggc tgctggatat tataatgata gtggtgctcc agacttaaat gtgattgatg
     5341 ggaatttaaa aatacctttt attatattgg aatattttaa aagttgtaat tatgggcgat
     5401 tcattaacat tggtagttac tgggagttta gctgttctgg cagaggcgtt aaaggtgtaa
     5461 atccttatgg aataataaaa tcgacagtta gaaggctgtt agattattat tcaaaatata
     5521 atgtgatata cacaaattta atattatatg gttcatatgg tgataatgat catcgaggta
     5581 aaatagttga ctgcattata gatgcagtta actccaatga aactctaaag ttatcaccag
     5641 gtgagcaaaa actaaatcta gtttacattg atgatataat tgaggcgatt ttatacatag
     5701 tatcatctga caatggacaa tatgataatg aaacattatc aatttacact cccactgaac
     5761 atacagtaaa agagattgtt tgttttataa atgaaatcaa agataacaat ctatcattag
     5821 gaggtggaag gtatagaaat gatgaggtaa tggctcctga ttataaatat agaaatattt
     5881 ttcatgctaa agataaattg aaagaatata tcacctctaa aataaaaaaa taatatattt
     5941 ttttgtgttg aatttttttg ttatttaaat atattcttga tgcattttac cccaatgcct
     6001 aagtatataa taggtgcaac cagcacatgg gaattagctg ttcagtagtt accacaacga
     6061 acggtagcta aggtttctgg ctatgatctc aggcagctcc tgctataacc gttcaatatg
     6121 gttgacctat ggcgagtaag ttatttgata aataaaaata aatacagggt taccccttaa
     6181 tcagggatgc tctccacaac ttttatggat aatgtagtta tcaacaataa atgttatggt
     6241 tcttgcacac cgatatgtat tcttaagatg ctgcaatgta ttgataaata aagctgagtt
     6301 tttgctgttt ccgccaacgt aataatctgg tgtactagtg atgaatatgc acaaaagaga
     6361 gttctactcg ttgactgtgt cacctggtga agcaccagat ggtggtgagt ctgtaggtat
     6421 ggttctggtc gcgagatagt ttaaatgatc gtttctgatg atttttctca ctatgagata
     6481 acctaaagtt attacaatta ttcggagact ttttccatgt acattatgat attttaaata
     6541 gaaatgatgt tactagacta attcgggaat ttaagtccga tgaccttttc catctcacta
     6601 gttaagttgc aatgacgaca tctattgata atccatcaag tggatttcaa cgttaatgtc
     6661 agtggggaat ttaatcttct cgaagtaata catgtattta atcttgaatg tagctttatt
     6721 tttcttcata aattaggtat atcaggattt ataacagttc ccacatcgag aaaccgagag
     6781 gcgctatgag tgtatcgaaa tgccagatgg atttgatgag agcacgcagc taactttcca
     6841 ttctccttat ggttgctcta aaggtgctgc ggatcagtat atgctagatt atgcacgtat
     6901 atatgggctc aaaactgttg tttttcgtca ttcctcaatg tatggcggtc gtcaattttc
     6961 gacatatgat caaggctggg ttgggtggtt ttgtcagaaa gctatagaag cgagtcgagg
     7021 tgttaatagc ccattcacta tttcgggtaa tgggaagcaa gttcgagatg ttttacatgc
     7081 ggaagacatc atctcacttt atttctcaac gctatctaac ttagaacgtg ttaaaggtaa
     7141 tgcatttaat attggtggta caattgagca tagcctatct ttacttgagt tattctcttt
     7201 actagaaaaa tatacagaaa cagagttaaa atatacgaga ataccagtaa gggaaagtga
     7261 ccagaaagta tttgtggcaa atataaataa aatatcagag agtactggtt ggattccaaa
     7321 agtgtcatct gaaagtggca taaaaattat gcttgattgg gttgaaactg tttaaaatat
     7381 agttctttag tggagtttaa aattaattgc gggtacctac acatataata gttgcagcaa
     7441 gtgcatgggg gagtcggtta gtatctatat ttatccaatt ttatagtatt aaaattttat
     7501 tggatctatt gggtacggaa ggatatgctg tttttaccgt tattggtagc ctagttggtt
     7561 ggttcctgct tgcggatttt ggtctcggta atagccttca gaatcaaata tcatatagga
     7621 gagcaaatca tcaagaatat caagatttag ttttatctgc agtaatagct ataataccta
     7681 tttttatttt attcataatt ttaatattaa cactgtcacc ttatatatct gagttcctcc
     7741 ttggtggatt tgatttttta aacaacaatc agagaagcaa tatatttaaa gtggcatctt
     7801 ttattttctt aactacatcc attggtaatt tagcatataa aatatggttt tcagagcata
     7861 aaggatgggt ttctaatata atccccgcat tatcatctat tgttggactc gtttttttga
     7921 tgagactacc atctgatgga agcaatatta gtgaagatat tattttttct atttattgtt
     7981 tttatattcc agctgcattt tttggtgtaa tatctacttt atttaaagtc ataccttatt
     8041 taaaatgtaa aaatttttta aataagttga cactttatac tctaataaaa aatggaggcg
     8101 gttttttcct atttagtgta ctatcggcac ttgtacttca agttgactac attgttatgt
     8161 cacagacgtt agtagaaaga gatttagtaa cgtataacat aatgagtaaa acttttggtt
     8221 taattaactt catatatgcg gctttattgc aatcactttg gcctgtatgt gcagaggcaa
     8281 gttcaaaact aaggtttgat aatttttata aaatagaaaa aaaatatata tcgtttggtt
     8341 ttattattgt tattgcaagt tcatttgtta tttttttatt aaaagacttt attgtaaata
     8401 tactcgcacc tggaaaagac ttctatttcc ctattagttt gattatattg ttttcctttt
     8461 atcaagtggt aagggtgtgg actgatacat atgctatgtt tctcatgagt attggtaaat
     8521 taaaaccact ctggattagt gttccctttc aagctgtatt aagtggttca cttcaatggg
     8581 ttggtgcagt aaattatggt ttggtaggat tactttgtgg attaatagca tccttcttaa
     8641 ttaccgtttc atggtggttg cctttcagtt ttcgatctac agtagataga atagttaagg
     8701 acaaacgttt agatgagtaa tattaaaata tcattttgta ttcctacgta taatcgttct
     8761 gagttattat cagaactaat tgaaagtatt gtttcacaat gtaaaaatag aaatgatatt
     8821 gaaatatgta tttcagataa tgcatcttca gataatacat ctgaaatgat tgctaaatgg
     8881 aaagagagta ctgacactcc aatagtttat caagtaaata aggaaaatat tgggccagat
     8941 agaaattatc ttgctgccgt agacttggct tctggtgaat attgttggtt gtttggtagt
     9001 gatgatagat tgctatctga tgcaataatt aaaatggatg aacatatcaa tgaaggacat
     9061 gatatctata tcgtagatag gatagaatgc gattttaata tgaagccatt tagtcacaga
     9121 acgtggatga gcacgggtag taaattatat aatacatcta aacgaactga tttaattgag
     9181 tacttcaata atagttatgc agtgggtgcg gtatttagtt acctaagctc tattatagtg
     9241 aagcgaagtc gatggaatag agtaaaattt aatcctaaat ttataggtag ttgttatgca
     9301 catgtttttt atttattaga tatagttaat aatggtgccg agcttaaata tgtgaagtct
     9361 gcatttgttc tttcaagagg gggaaatgat agttttgctg ctaatggatt aataaaaaga
     9421 attgaaattg atttcgatgg ttatttttta ttagggaatg aatttttttc taatgatttt
     9481 tatttgaatt caaagttcaa agctattctt cttaaagaac atcctgttat tcacacctgt
     9541 attaaaactg ctatgatagg cgaatttcaa gatttaaata aaattaagag gttttatatt
     9601 gagctaggta tagcacctta ttatgttagt attatttatt tttttaagcc tatatatcaa
     9661 ttggcaaata aaatgaaatt atcttttttt tataaaaaac tacgaaaaaa aataactttc
     9721 aagaaaggta gttttaattc tatagattaa attaattaat aataaagttc agagtgaaaa
     9781 ataaatgaat attttaattg tatatttagg ccggaaaggt ggtggcgcac actacacata
     9841 tgaattagtt aatgaattat cgaagaaaac gaatgtgtct ttattagtgt ctaagcaagc
     9901 agagaatatt aagtcttatg aaagtctaaa tatatcactc aatactataa atacattcaa
     9961 tggtatgttt tcatttatac tctcaagctt taaattgcca tttataaaaa ataaaataaa
    10021 gaaaattatt ttagatgaaa agatagatat agtcatatct acaatgacac atgtatggaa
    10081 tggttttatt tttactccaa attttatgat gaaaatacca tatatattaa cgatccatga
    10141 tgctgtacct cattcaggag aggagaactt tattttaaat ttactcaaca ataaggatat
    10201 aaaaaatgcg aatgcatata tcgcattgac tgaacatgtc aagaatcaat ttattaatat
    10261 ttatggagat aagaaggata tatgcatttt gccattggga tcgttcaatt ttaaaagtgg
    10321 cgagataaaa agttggtgtg gtgttaggcc attacggatt ctattctttg gtagaataca
    10381 tgagtataaa ggcattgatt tgctattaga ctctatgatt attttacagg aaaaatatga
    10441 tctagagtta tccatttatg gacaaggcga tctttctgat tatgttgata aaattgatgt
    10501 aataaaaaaa ataaatattg aaaaccgatg gattggtgat tctgaagttg gtgatatatt
    10561 acaggcacat gatgtatgtg ttataccgta taaggatgct agccaatctg gtgttatacc
    10621 tgttgcacaa tctgctggac ttcctacgat tgtaaatcct gtcgatggat taattgagca
    10681 gatagaaaaa gataaaacta gcttagtcac agatagggtc gactcagttt cattagcttt
    10741 atccatagag aaaataatta aaaatccaga gttagtgaat aaattatcta taggttcact
    10801 agaatatgca tccagaaaat taagttgggt tcctattgtt aataaattaa ttacttatag
    10861 taaagaaact ttaaatagta gtgacagatc ctagttttat cattaagtaa tagagtgagt
    10921 tataagatgt atattctatt tttagcgtta tataatatat tgagcttaaa tatatgctat
    10981 ataaaaaaga atttattcta ctaatattag tcaaggtgtt gttctcgttt ttcgcttttt
    11041 ttatatatag taatttttcc caacttgggg actctaatag atatttaaat gcaacactta
    11101 attttaataa cattctggat agaactcaat ttgtagataa tacgtttgct tttctaaagt
    11161 atgtaatgtc tagttcatta ttagttaata tttctatatc tgttctattc ggttattcat
    11221 ttttctatgt ttttaaagat gttcttattt ttgtagataa aaaattatta tatatgtctt
    11281 tccttcttcc aagttttcaa atttggacaa gcgttgcagg gaaagaaatt attgctgtga
    11341 taggattcct tttttttata aagtgggtca taaatattca atttggcagg gataatcgta
    11401 tacattatct tgttataggt attttattcg gagtttttct taggccacat tatggtattg
    11461 cttatattta tcttgctatc agcgctatta ttttaagtag aataaaattc agagtattct
    11521 ccaatgggtt ttatgtgttg tcattgttta tcatagctat aatgttgttt cttgtgttag
    11581 cgttaacagt gaatatttgg agtgcgcagt tcttatcagt tttggatact attgaaggct
    11641 attttttatc ctatgatgcc tctaattcta atagatatga tatcgagtgg ggaacaattt
    11701 cagactattt ttataatata acatggggtt tttttatttc aattattggg cctactttaa
    11761 atgaaacact caatcgagtg gtttatctcc cattctttat agaaggtatt ttaagtttta
    11821 tattaatgat tgtcatatct tatcgtttat ataaatcgac taatgaaaat gtattatata
    11881 gaaagttatt ttacttttct tttcttccgg cacttatcat catattaatg attcattatc
    11941 cttttggact ttttaatcca ggatctgcga taagatataa gcaaaacatt actccattga
    12001 tatactttta tccattacta atgctggcat gtattaataa atataaggtt aagggatagt
    12061 gcggtatttt tatcgagaaa aattgattta tatttttctg tgtgggaata ttatttactc
    12121 tcttctctta ataagatgag ttgggatttt aatgtcgatt taattagtgt attggtcttt
    12181 atatttttag gctgaatggg tatgagttta attaggccct gatatgttat tttttggttg
    12241 gttaaaatga aacttaagaa aatacttctt tgcggtaata gttcatggtc tatgtataat
    12301 tttcgtttgg gtgttattaa atttttaatt tctaatcaat attctgttgt tattttagct
    12361 ccaagagatg attattcaga taagctaata tctattggtt gcaagttcat agatataaac
    12421 ctgtctgcac aaggggtcaa tcctttcaat gaattaaagt ttttattttc tttagtttca
    12481 atttacagag aagagaaacc agatttcatt attaactata caattaaacc caatatatat
    12541 ggatctttgg cttcaaaagt aaccaatatt ccatcaatag ctataactac gggactcggt
    12601 tttgttttta cacgtaaaag tatagtgtct tttttcgcaa agctattata taaaatagct
    12661 ctatcttgtt gtcaagaagt ttggttttta aatagtgatg atcaagacgt ttttttgcgt
    12721 aaaaatattg taaataagaa taagacaaaa atactctaca gtgaaggaat tgatgtaact
    12781 catttttcgc caaggaaaag aaatgatcat catgatgaag atactttttg ctttttactg
    12841 gtagcaagga tgttacggga taaaggagta cctgagtttg tatctgctgc cagaattatt
    12901 aagaagaaat atcctaatgt atcttttcgt ctattaggat tttgtgatgt agaaaatcct
    12961 agtgcgatta ctcgtagtga aattgattca tgggttaatg aaggggttgt cgaatactta
    13021 ggtgtaaccg atgatgttag acaatatatc gctgattccc agtgtattgt attaccctca
    13081 tcatatagag aaggaattcc tcgaatttta atggaggcgg catcaatggc taaaccggtg
    13141 ataacaacta ataatgtagg atgccgggaa gttattcttg atgaagtaac cggatatctt
    13201 tgtgaagtta ataatgtaga ctctctggtt tctgcatgtg aaaaattgct tagtttagat
    13261 gaggcccaga ttattgatat gggaaaaaaa ggacgaaaac ttgtcgagga aaaattttct
    13321 gaagaaaaga taatctcaca atattctgaa tgcataaatt attatttaat agaaaaataa
    13381 attaaataga taccccgctg agatataaaa tatattattt gtcaatgaca ctctatattt
    13441 ttatttgttt ttttgcattt tcctttaatt ttttatggtt aaatttttta atcattctta
    13501 catatgttga tataataagt agtggttttt cccattggct gttaaagtgg ttttattaat
    13561 tttttttaaa atcgatgaca ttggctgtaa aaatataacc tataggtttt tatatgacaa
    13621 aggtgtttat attaggttcc aacggctata ttggtaataa tttaatggag tcattgtgtg
    13681 ataatattga agtcattact gttgggagaa gtaatgcgga tatttatata aatcttgagt
    13741 ctgacgattt tcaatcttta ttaaataagg tggaatttaa agataccgtt attttcctgt
    13801 cagcaatatc atcaccagat gaatgtaata ataactacaa ttattcatat aaaataaatg
    13861 ttaaaaatac gatttctcta atatctttgc ttttggctaa aaatgtaaga gtgatgtttt
    13921 catccagcga tgcggttttt ggtgcaactc agaatttatg tgatgaaaat tctgaaaaaa
    13981 aaccatttgg aaaatatgga gaaatgaagt ccgaggtaga agactacttt acattagagg
    14041 atgatttttt tgtcgtaaga ttttcttatg ttttagggag gaatgataag ttttctatga
    14101 tgattaaaga attttatgag caaggtaaaa ttcttgatgt ttttgatggg ttcgaaagaa
    14161 atgttatttc aataaacgat gtgactgcag gcataaaaaa tatcatatgt gattgggata
    14221 gtatcaaaac aagaatagtg aatttttcag ggaacgaatt agtaagtaga caagatattg
    14281 ttaacgctct agttaaagag aaatatttaa atttgaaata taagtttaca gcggcccccg
    14341 agagtttctg ggtaggaaga cccaaaaaaa ttcataccaa aagtaactat ttagaatcga
    14401 tattgaatag aaagcttgag ccatatctgg aagtaattaa ggaataaata tgaataatgt
    14461 tttaattaca ggttttacag gacaagtagg atcgcagtta gctgattata ttttagaaaa
    14521 taccgatgat cacgttattg gcatgatgcg ctggcaagag tcgatggata acatctatca
    14581 tcttactgat agaattaata aaaaagatcg aatttcaata caatatgctg accttaatga
    14641 tttaatgtca ttatataatc ttattgatac tgtaaggcca aaattcattt ttcacctggc
    14701 tgctcaatct tttccgcgta cttcatttga tattccaatt gaaacgcttc aaacaaatat
    14761 tataggtact gctaatctat tagagtgtat cagaaaactg aaacaacaag atggatacga
    14821 tcccgttgtg catgtgtgtt cttctagtga agtatatggc agggctaaag ttggtgaggc
    14881 attaaatgaa gatactcaat ttcatggtgc aagcccctat agtatcagta aaattggtac
    14941 tgactaccta gggcaattct acggtgaagc atatggtatt agaacttttg tgactcgaat
    15001 ggggacgcat acaggacctc gtcgtagtga tgtttttttt gaaagtactg tagctaagca
    15061 gattgctcta attgaggctg gacatcaaga gcctaaattg aaagtaggga atcttgctag
    15121 cgttaggact ttccaagatg ctcgagatgc agtccgtgct tattatctgt tagcacttga
    15181 aagtggaaaa ggaaatatac ccaatggaga agtatttaat attgcaggtg atgaagcatt
    15241 caagctacct gaagttattg aactactttt aagttttagt acacgaaatg atatagaggt
    15301 agtgacggat accgatcgtt tgagacctat tgatgcagat tatcaaatgt ttgatagcac
    15361 aaaaattaag tcatatatca actggaaacc tgaaattaag gctgctgata tgttcagaga
    15421 cttgctccaa cactggagaa atgaaattgc atcaggtcgc attccattaa atcgctaatc
    15481 ttagggcatt agtttatgaa aataagaagt aaagctcctc tacgtttagg gatagctggt
    15541 ggtgggacgg atgtatcacc atacagtgat acctttggtg gttgtgttct taatgcaaca
    15601 attaatatgt atgcttatgc atatattgat gatgaattag atgaaaacaa ggttatattt
    15661 gaggctgccg atcttggttt aagagaggaa ataaaccttg ataaagaaat aaatatagaa
    15721 ggtcaattaa agctacatag ggctgtatat ctacgtgtga tgaaagatta ctttggtgga
    15781 gaattaaagc ctattagaat tattacgcac tcagatgcac ccgcaggaag cgggcttggt
    15841 tcttcttcaa ccgttgtagt gtcaatgcta gaagggttac gtcagatgta ttctcttcct
    15901 cttggtgaat atgatttggc gcaattagca tttaagattg aacgagttga ctgtggactc
    15961 tctggaggca aacaggacca gtatgctgct acctttggtg gttttaattt tatggagttt
    16021 tacaaatgca atcgagttat cgtaaatccg ttaagaatcc gtagatatat cattaacgaa
    16081 cttgaatcat ctttgatact atattttaca ggagcatcaa gagattccgc aaaaatcatt
    16141 aatgaacaaa tcaaatcatt agaggaaaag aaaggttcta aacttgaggc aatgcataga
    16201 gtaaaagaat ctgcttataa aataaaagaa tatttgctta agtctgatat agatgctatg
    16261 tcatctacct ttcttgatgc atggagaagc aagaaggaaa catcatcttc aataacaaat
    16321 cctatgattg aggaaattga gatggagata ttcaatattg gtgctaagtc tatgaaagta
    16381 tctggcgcag gtggtggggg atttatgatg atatttgttg aacccgagaa aaaacatatt
    16441 gtagaaaata aacttaaagc gtttggtggt gaagtatata agtttcagtt tgttgaagag
    16501 ggagcatatt catggacaat ttaaattata ttcaaaaata tttggaaaat agcatctccg
    16561 ttaaaagaac gttacaagag tcaaaggagg ttttagagca agtttctcta gtcactgatt
    16621 taataataga agcatataga aatggtaata aggtgattct tgctggtaac ggtggtagtg
    16681 cggcagattc tcagcatatt gctgctgaat ttgtaagtcg ttttttcttt gaccgtccag
    16741 gtttgccagc gatggctcta acaactgaca catcaatgtt gactgcaatt ggaaatgatt
    16801 atggttttga taaactgttt tcacgacagc tacaggcaca aagtaggcct ggcgatgtat
    16861 ttatcggaat tagcacatct ggtaattccg aaaatataat caatgcaatg aaactgacta
    16921 aagagcttgg tgtaacgagt gttgctttat gtggtgaaag tggaaaattg aaagaaatag
    16981 ttgattattc tattaatgta ccatcaaaaa taacacctta tattcaagaa tgtcatattt
    17041 gtattggtca tatgatttgt gcaattgttg aaaaagtaat ttttgggtcg gaagataatt
    17101 aatatgtatg atgtggtcat tttagccggt ggacttggga ctagattaaa aagtgttagt
    17161 ggtgacattc ctaagcctat ggtggatatt tctggaaaac cttttttgta tagacttatg
    17221 gaataccttg aagatcaggg ggtacaaaga ataattttat ccttatcata taaagcagat
    17281 tatattattg atagccttat caaagacaat ccggttaata gcaaagtcga ttttattatt
    17341 gaaaatgaac ctttagggac aggtggagca ataaaaaatg cttgtaaata tattgaggca
    17401 agcaagttta tagttatcaa tggtgatact tattgtgaac ttgattataa aaaattcata
    17461 gagtcttcac ttgattcaga tttacaaata tccggagttg aagttgacga tgtttgtaga
    17521 tacggtagtt tagatattga ccatgatttt catgtaaact ctatcgttga aaaaggtcgt
    17581 caggggacag gaattattaa tagtggtact tatatactat ctaaaaaaat cattgaggat
    17641 tatcctcatg ataaattctc ttttgagctt gattttttac ctaaattcac tggtgtcttt
    17701 aaggcatttg ttactaaagc atatttcatt gatataggga tacctgaaga ctattataaa
    17761 gcatgtgaga aatttaaatg aaaattgcat ttttagatcg cgacggtgta attaataaag
    17821 aagtgaatta tctttataag atagatgatt ttgtttttac acctaattgt attgacgggt
    17881 taagaaggct tagggaaaaa aattttgaaa tcgtaattat cacaaatcag gctggcattg
    17941 ccaaagggtt ttatagtgtc gatgactata atgatcttac gttttggtac agagaaaaac
    18001 tgctatctta tggagtagat atattagata ttttatattg tcctcatcat ccaaatggat
    18061 gtgtccctga gtatagtatt gagtgtaact gccgtaaacc gaaaacaggt ttgcttgagg
    18121 aggtggcaaa aaagtatcaa attgatataa aagaatcaat tttggttggt gataaacaaa
    18181 gtgatttaaa cgctggtatt agtttcggca tatcaaaagt atatctagtt gaaactgggc
    18241 acaaaattcc aaaagaaaac tacaaaaaat atcacgtgta ttctgattta tcatgtatcc
    18301 cattatgaaa aaataagtca tatcactatg cctactcata ctcacacttt gatgagtttt
    18361 ttttggggag aaatataaag ctgattttat aaactattag atgtttttta gtggcatctg
    18421 tatttttcaa tatcggttat tgcgggttac tactttgttt aagagaaaat ataaactggc
    18481 tgcttaataa tgaagctaga ttttttaacc aatctacatt tttacgaatg agctaattat
    18541 gaatgtacag tatgatttct ctgaggcaca tgtttaacgg gttatgtaat atattgatga
    18601 attatcttaa atgtttactt gctctattgg tgtcaataac tcaccccatt tacatctgta
    18661 accagaaaaa taatattcct ccttgtgtgg tgttacattt tgctagcctt ttaggctaca
    18721 gttagcgcta gttttagggt ttaagttaat ataaacttac gtagatatat aggtaatact
    18781 caatgagtaa taaacaggca cgaaataacc ttgataaccc aatgccgaat aactatgatt
    18841 tttcaaatgt atcttcttca agaaatgaaa ttgatctctt tgaaattttt ggtgttgtat
    18901 ttaaatcaaa gttcaagata atattaataa cactattttt cttaattagt ggtttagtgg
    18961 tctcatatat cctcccccaa aaatggacaa gcactgcaat aatagctctt cctggtgatg
    19021 agcaagttca agttctggat gaactaatca caaatctgac cgtgcttgat ataaaggttg
    19081 atgtgagtgc taattatttg ctgtcaacat tcaaacaaaa tttcgattct caagatctcc
    19141 gtgaacaata tttagtaaat actaattact ttaaacgttt gatgaagaat aatccagaag
    19201 atggtttgga taaaagagcg ttaatagagc gaatcgtaaa tgaaaatatt tcttcggtta
    19261 acccattgaa agataaaacc gagggtgaaa atgaatatcg ctattataaa ttatcatata
    19321 gtgcaagcac accgacagac gctcgtgact tgttgcaagg ctctattaac tatgtaaata
    19381 ccatcgttaa tgctgatgtt ttccgaaaaa tacagcgagc agtggattta gccaagggta
    19441 tcggtacaga taaatactct atggaattat tgaaagctag aaataaccaa aaagttaaaa
    19501 ttgagcgctt aaggtatgct tcttctatcg ctgatgccgc aggcgtaaaa aaaccagttt
    19561 acagcaatgg ctcagccatt agtgatgatc cagacttccc tattactatg ggatccgatg
    19621 cgctgaaccg taaactggaa atagagaagt cagttatcga cctggcttca atcaatactg
    19681 aacttctaaa ccgtaagttg tatttggata aattaaatag gttagaaatt cctaatgtta
    19741 atattgtgcc atttaaatat ttgcaacagc caacggaacc cactaaaaga gatgccccta
    19801 agcgcgcatt gattgtgatt ctgtttgccc tggtcggtct tatgggttct gtcggttttg
    19861 ttttagttga gcactttgtg cgtgaacgga agcgagaaga agaggggctt aagctctctc
    19921 aaactaagga ataggtttta aacgaattta tctaacggct gggtgaggtt tctcatctgg
    19981 ccgttctgtt ttatcgctct gtattatttt actatttttc cgtttttaag ttagctgcta
    20041 ctatttgctt gtaactaatt cccctgcatt atgcttccca gcaaccctta tgctaaaatt
    20101 cgttatcttt tcatcgctag atttt
//
